CN1480111A - Individualized artificial half joint substitute and its preparing method - Google Patents

Individualized artificial half joint substitute and its preparing method Download PDF

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Publication number
CN1480111A
CN1480111A CNA031343759A CN03134375A CN1480111A CN 1480111 A CN1480111 A CN 1480111A CN A031343759 A CNA031343759 A CN A031343759A CN 03134375 A CN03134375 A CN 03134375A CN 1480111 A CN1480111 A CN 1480111A
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China
Prior art keywords
artificial
substitute
demifacet
bone
individuation
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CNA031343759A
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CN1267068C (en
Inventor
李涤尘
王臻
孙明林
卢秉恒
张虎
腾勇
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Xian Jiaotong University
Fourth Military Medical University FMMU
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Xian Jiaotong University
Fourth Military Medical University FMMU
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Priority to CN 03134375 priority Critical patent/CN1267068C/en
Publication of CN1480111A publication Critical patent/CN1480111A/en
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Abstract

A substitute of personalized artificial semi-facies articularis is composed of semi-articulation body, bioconnector, connecting pile for intramedullary needle, and locator for operation. An artificial articulation is prepared through CT scanning to articulation of patient, image processing, 3D reconfigurating by software, designing semi-articulation body, designing said bioconnector, connecting pile and locating die, fast shaping to obtain prototype, precise fusion casting, and assembling.

Description

Individuation artificial demifacet substitute preparation method and artificial semiarthrosis substitute thereof
One, technical field
The present invention relates to the osteoarthrosis reparation of medical industry.
Two, background technology
The artificial joint substitute that prior art is used has dual mode: a kind of method is a bilateral total replacement artificial joint, it has excised offside does not still have impaired articular surface, increased range of operation, be unfavorable for postoperative rehabilitation and functional rehabilitation, particularly for budding adolescent patient, the destruction to epiphysis that osteotomy causes has been destroyed the developmental capacity of limbs; Another kind method is to use allogenic bone transplantation, and its existence operation posterior articular facet necrosis and articular surface matching are poor, thereby influences the problem of joint function recovery.Above method all is difficult to solve the individuation displacement.
Three, summary of the invention
Goal of the invention of the present invention provides a kind of computer-aided design (CAD) and rapid shaping (Rapid Prototyping) technology utilized, according to patient CT graphical design and the artificial demifacet substitute of manufacturing individuation preparation method.
Another goal of the invention of the present invention provides the artificial demifacet substitute of individuation.
The invention provides locator for operation at the artificial demifacet substitute of above individuation.
The technical scheme that realizes goal of the invention is to solve like this: the artificial demifacet substitute of individuation preparation method is undertaken by following step successively:
A, utilize the patient to perfect the side joint to carry out CT scan, obtain the osseous tissue view data;
B, utilize image processing techniques, pictorial data is carried out mirror symmetry processing, the difference of gray scale in the CT image is carried out image segmentation according to soft tissue and sclerotin, extracts outline data, obtains articular cartilage and bone contours data;
C, with the bone outline data that obtains, import anti-software or the CAD software asked and carry out joint surface of bone three-dimensionalreconstruction;
D, biological adapter of design and intramedullary needle connection stake on the surface of bone of joint;
E, according to the artificial demifacet of designed individuation, the design of the localizer that undergos surgery and manufacturing;
F, the cad model that designs is changed into the rapid shaping file format, be prepared into the prototype of artificial demifacet substitute with rapid shaping technique;
G, prototype is implemented post processing, accurate fusible pattern casting is prepared into artificial semiarthrosis substitute;
H, the artificial semiarthrosis of whole assembling.
The invention provides the substitute Therapeutic Method of one-sided articular surface, only change impaired one-sided articular surface, and its impaired preceding articular surface of the outer surface of articular surface substitute is identical, realized the matched motion of substitute and offside articular surface.In the syndeton of the inner surface of articular surface substitute, biological adapter is installed on the face is connected stake with intramedullary needle.Biological adapter is the cylindrical drum parallel with the intramedullary needle direction, has the aperture of 4-6mm around the tube, wherein will insert from body spongy bone or artificial bio-membrane's material.Intramedullary needle connection stake is a cylinder table on the inner surface, be the taper hole of self-locking Morse's taper for tapering in the cylinder table, definite method of its direction is: get the maximum cross-section and the smallest cross-sectional of patient's femur respectively, connect the center of two sections, this direction be intramedullary needle connects the direction of stake; Intramedullary needle connects stake and will be connected with the intramedullary needle of installation in the operation.Be the installation of assurance operation articular surface substitute, the locator for operation of invention articular surface substitute, its structure comprises positioning module and clamp device.Positioning module is the rapid shaping spare of datum level with the curved surface of articular surface, and three locating holes are wherein arranged, respectively corresponding intramedullary needle and biological adapter direction and size.Locator for operation comprises by the pedestal of clamp device, bottom end clip and top anchor clamps and forming that stationary positioned mould and reparation bone are convenient to operation technique.
The present invention compares with total joint replacement commonly used at present, has not only solved individual coupling manufacturing issue, and having kept offside does not simultaneously have impaired articular surface, has reduced range of operation, is beneficial to postoperative rehabilitation and functional rehabilitation.Particularly, reduced the destruction that osteotomy causes, at utmost the developmental capacity of limb preservation to epiphysis for budding adolescent patient.Whole system all adopts Rapid Manufacturing Technology, for needs such as wound at short notice the case of operative treatment temporal guarantee is provided.Biological adapter can realize that with medullar nail system prosthese is connected with the biological of host bone, late complications such as minimizing is loosening, pain.Be applicable to the normal semiarthrosis damage of offside articular surface patient, comprise that the demifacet that a variety of causes such as wound, tumor, arthritis cause destroys the case that need carry out the prosthetic replacement.Can carry out the design and the manufacturing of individuation according to each patient's different degree of impairments.
The artificial semiarthrosis substitute of bionical individuation has following characteristics: 1. intraarticular is worn two biological adapters, and is built-in from skeletal growth factors such as body bone and BMP, FGF, TGF during operation, plays the biological fixation articular surface.2. the artificial joint face is an outer surface with patient's Ipsilateral articular cartilage outer surface profile.Inner surface is decided because of the difference of performing the operation, and can be the allograph bone outer surface, also can be that operation is revised from body bone outer surface.3. artificial joint combines with intramedullary needle.4. individuation manufacturing.This design and manufacturing can reach the optimum matching of artificial joint face and patient's normal side articular surface.
Propose at the artificial semiarthrosis substitute of individuation, it is poor to solve allogenic bone transplantation operation posterior articular facet necrosis and articular surface matching, thereby influences the problem of joint function recovery.What propose utilizes modern computer and engineering technology, according to the artificial demifacet manufacture method of individuation of the alternate articular surface shape of patient CT copying image.The articular surface that produces with this kind method is used with big section allograph bone or from the body bone, to solve the problem of joint cartilage in the one-sided transplant operation of allograph bone.Can obtain the ideal physiology of articular surface rebuilds and the later stage excellent function.
Four, description of drawings
Fig. 1 is preparation flow figure of the present invention;
Fig. 2 is an intraarticular surface texture sketch map;
Fig. 3 is a joint outer surface structure sketch map;
Fig. 4 is the locator for operation structural representation.
Five, the specific embodiment
Accompanying drawing is wherein a kind of embodiment of the present invention.
Below in conjunction with accompanying drawing content of the present invention is described further:
With reference to shown in Figure 1, flow chart is preparation method of the present invention, is undertaken by following step successively:
A, utilize the patient to perfect the side joint to carry out CT scan, obtain the osseous tissue view data;
B, utilize image processing techniques, pictorial data is carried out mirror symmetry processing, the difference of gray scale in the CT image is carried out image segmentation according to soft tissue and sclerotin, extracts outline data, obtains articular cartilage and bone contours data;
C, with the bone outline data that obtains, import anti-software or the CAD software asked and carry out joint surface of bone three-dimensionalreconstruction;
D, biological adapter of design and intramedullary needle connection stake on the surface of bone of joint are to improve the fastness that prosthese is installed in human body;
E, according to the artificial demifacet of designed individuation, the design of the localizer that undergos surgery and manufacturing;
F, the cad model that designs is changed into the rapid shaping file format, be prepared into the prototype of artificial demifacet substitute with rapid shaping technique;
G, prototype is implemented post processing, accurate fusible pattern casting is prepared into artificial semiarthrosis substitute;
H, the artificial semiarthrosis of whole assembling.
Rapid shaping technique is a kind of emerging digitized manufacturing technology, under the control of computer, according to data such as the cad model of object or CT, by the accumulation molding of material, makes the prototype of arbitrary structures fast.The characteristics of rapid shaping technique are the production that is particularly suitable for labyrinth object, single-piece or small lot object.Combine with CT at medical domain,, can realize that biological substitution thing individuation such as joint makes fast at the accurately individuation specific (special) requirements of coupling of one-sided articular surface.
Fig. 2, Fig. 3, shown in Figure 4, individuation demifacet substitute comprise by semi-articulation body 4, biological adapter 1, intramedullary needle connection stake 3 and locator for operation and forming.Individuation demifacet substitute is the metal material manufacturing.Biological adapter 1 is installed on the syndeton of the inner surface 2 of semi-articulation body 4 substitutes is connected stake 3 with intramedullary needle, it is the cylindrical drum parallel with the intramedullary needle direction that biological adapter 1 is provided with its structure, have the aperture of 4-6mm around the tube, wherein will insert from body spongy bone or artificial bio-membrane's material.Intramedullary needle connection stake 3 is cylinder tables on the inner surface 2, be the taper hole of self-locking Morse's taper (3 °) for tapering in the cylinder table, definite method of its direction is: the maximum cross-section and the smallest cross-sectional of getting patient's femur respectively, the center that connects two sections, this direction be intramedullary needle connects the direction of stake 3; Intramedullary needle connects stake 3 and will be connected with the intramedullary needle of installation in the operation.Be the installation of assurance operation articular surface substitute, the locator for operation of invention articular surface substitute, its structure comprises positioning module and clamp device.Positioning module 12 is the rapid shaping spare of datum level with the curved surface of articular surface, three locating holes are wherein arranged, be respectively intramedullary needle sight hole 5 and biological adapter sight hole 6, clamp device is made up of pedestal 9, bottom end clip 10 and top anchor clamps 11, be used for fixing positioning module 12 and be repaired bone 8, the curved surface of positioning module 12 is identical with articular surface curved surface 7 on being repaired bone 8.

Claims (6)

1, the artificial demifacet substitute of individuation preparation method is characterized in that the artificial demifacet substitute of individuation preparation method undertaken by following step successively:
A, utilize the patient perfect the side joint carry out (CT) scanning, obtain the osseous tissue view data;
B, utilize image processing techniques, pictorial data is carried out mirror symmetry processing, the difference of gray scale in (CT) image is carried out image segmentation according to soft tissue and sclerotin, extracts outline data, obtains articular cartilage and bone contours data;
C, with the bone outline data that obtains, import counter ask software or (CAD) software carry out joint surface of bone three-dimensionalreconstruction;
D, biological adapter of design and intramedullary needle connection stake on the surface of bone of joint;
E, according to the artificial demifacet of designed individuation, the design of the localizer that undergos surgery and manufacturing;
F, (CAD) model conversation that will design become the rapid shaping file format, are prepared into the prototype of artificial demifacet substitute with rapid shaping technique;
G, prototype is implemented post processing, accurate fusible pattern casting is prepared into artificial semiarthrosis substitute;
H, the artificial semiarthrosis of whole assembling.
2, the artificial demifacet substitute of individuation according to claim 1 preparation method is characterized in that only changing impaired one-sided articular surface, and the outer surface of articular surface substitute is identical with impaired preceding articular surface.
3, the artificial demifacet substitute of the described individuation of a kind of realization claim 1, it is characterized in that described artificial demifacet (4) substitute is the articular surface substitute of simulation simulation of human body, comprise a semi-articulation body (4) and inner surface (2), the locator for operation that biological adapter (1), intramedullary needle connect stake (3) and fixedly be repaired bone (8) is installed on the syndeton face of inner surface (2).
4, the artificial demifacet substitute of individuation according to claim 3, it is characterized in that based on described biological adapter (1), its structure is the cylindrical drum parallel with the intramedullary needle direction, has the aperture of 4-6mm around the tube, wherein will insert from body spongy bone or artificial bio-membrane's material.
5, the artificial demifacet substitute of individuation according to claim 3, it is characterized in that connecting stake (3) based on described intramedullary needle is a cylinder table on the inner surface (2), be the taper hole of self-locking Morse's taper for tapering in the cylinder table, definite method of its direction is: the maximum cross-section and the smallest cross-sectional of getting patient's femur respectively, the center that connects two sections, this direction be intramedullary needle connects the direction of stake (3); Intramedullary needle connects stake (3) and will be connected with the intramedullary needle of installation in the operation.
6, a kind of locator for operation that realizes that the artificial demifacet substitute of individuation is installed, it is characterized in that described locator for operation, its structure comprises positioning module (12) and clamp device, positioning module is the rapid shaping spare of datum level with the curved surface of articular surface, three locating holes are wherein arranged, respectively corresponding intramedullary needle and biological adapter direction and size; Clamp device by pedestal (9) be connected with bottom end clip (10), bottom end clip (10) is connected with top anchor clamps (11), top anchor clamps (11) stationary positioned moulds (12) and repair bone (8), the curved surface of positioning module 12 is identical with articular surface curved surface 7 on being repaired bone 8.
CN 03134375 2003-07-08 2003-07-08 Individualized artificial half joint substitute and its preparing method Expired - Fee Related CN1267068C (en)

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Cited By (23)

* Cited by examiner, † Cited by third party
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CN100528103C (en) * 2007-08-14 2009-08-19 西安交通大学 Bionic artificial semi-joint body and manufacturing technique thereof
CN100588379C (en) * 2008-06-26 2010-02-10 上海交通大学 Preparation of artificial joint prosthesis with partially controllable porous structure
CN101879086A (en) * 2010-06-22 2010-11-10 中国人民解放军第三军医大学第一附属医院 Fabrication method for fracture fixator
CN101396291B (en) * 2007-09-24 2010-12-08 上海交通大学医学院附属第九人民医院 Manufacture method of guide entity of individual mandibular angle hypertrophy operation
CN102048597A (en) * 2009-10-30 2011-05-11 德普伊产品公司 Prosthesis with modular extensions
CN102724934A (en) * 2009-11-04 2012-10-10 康复米斯公司 Patient-adapted and improved orthopedic implants, designs and related tools
CN103656760A (en) * 2013-12-09 2014-03-26 广西大学 Method for preparing individual porous thyroid cartilage support
CN103989541A (en) * 2014-05-19 2014-08-20 西安交通大学 Method for manufacturing high-strength composite bone and cartilage support with complex molded surface
CN104780872A (en) * 2012-09-21 2015-07-15 康复米斯公司 Methods and systems for optimizing design and manufacture of implant components using solid freeform fabrication
US9308091B2 (en) 2001-05-25 2016-04-12 Conformis, Inc. Devices and methods for treatment of facet and other joints
US9333085B2 (en) 2001-05-25 2016-05-10 Conformis, Inc. Patient selectable knee arthroplasty devices
CN105666762A (en) * 2016-03-01 2016-06-15 贵州师范大学 Manufacturing method of individual hip joint holder die
US9387079B2 (en) 2001-05-25 2016-07-12 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US9387083B2 (en) 2013-01-30 2016-07-12 Conformis, Inc. Acquiring and utilizing kinematic information for patient-adapted implants, tools and surgical procedures
US9408686B1 (en) 2012-01-20 2016-08-09 Conformis, Inc. Devices, systems and methods for manufacturing orthopedic implants
US9495483B2 (en) 2001-05-25 2016-11-15 Conformis, Inc. Automated Systems for manufacturing patient-specific orthopedic implants and instrumentation
US9603711B2 (en) 2001-05-25 2017-03-28 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
CN106725849A (en) * 2017-01-17 2017-05-31 武汉大学 A kind of fast conversion method of operation on mandible titanium plate osteotomy guide plate locus
US9775680B2 (en) 2001-05-25 2017-10-03 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
CN107334565A (en) * 2010-08-25 2017-11-10 史密夫和内修有限公司 Scanned in operation for implant optimization
CN108348340A (en) * 2015-09-30 2018-07-31 捷迈有限公司 Patient's particular instrument and method for patella surface prosthetic
US10085839B2 (en) 2004-01-05 2018-10-02 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
CN110090100A (en) * 2019-05-31 2019-08-06 攀枝花学院 The 3D printing production method of arm fracture fixing apparatus and arm fracture fixing apparatus

Cited By (32)

* Cited by examiner, † Cited by third party
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US9333085B2 (en) 2001-05-25 2016-05-10 Conformis, Inc. Patient selectable knee arthroplasty devices
US9308091B2 (en) 2001-05-25 2016-04-12 Conformis, Inc. Devices and methods for treatment of facet and other joints
US9439767B2 (en) 2001-05-25 2016-09-13 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US9387079B2 (en) 2001-05-25 2016-07-12 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US9775680B2 (en) 2001-05-25 2017-10-03 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US9495483B2 (en) 2001-05-25 2016-11-15 Conformis, Inc. Automated Systems for manufacturing patient-specific orthopedic implants and instrumentation
US9603711B2 (en) 2001-05-25 2017-03-28 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US10085839B2 (en) 2004-01-05 2018-10-02 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
CN100528103C (en) * 2007-08-14 2009-08-19 西安交通大学 Bionic artificial semi-joint body and manufacturing technique thereof
CN101396291B (en) * 2007-09-24 2010-12-08 上海交通大学医学院附属第九人民医院 Manufacture method of guide entity of individual mandibular angle hypertrophy operation
CN100588379C (en) * 2008-06-26 2010-02-10 上海交通大学 Preparation of artificial joint prosthesis with partially controllable porous structure
CN102048597A (en) * 2009-10-30 2011-05-11 德普伊产品公司 Prosthesis with modular extensions
CN102048597B (en) * 2009-10-30 2015-11-25 德普伊产品公司 There is the prosthese of modular extensions
CN102724934A (en) * 2009-11-04 2012-10-10 康复米斯公司 Patient-adapted and improved orthopedic implants, designs and related tools
CN101879086A (en) * 2010-06-22 2010-11-10 中国人民解放军第三军医大学第一附属医院 Fabrication method for fracture fixator
CN107334565A (en) * 2010-08-25 2017-11-10 史密夫和内修有限公司 Scanned in operation for implant optimization
US9408686B1 (en) 2012-01-20 2016-08-09 Conformis, Inc. Devices, systems and methods for manufacturing orthopedic implants
US10456261B2 (en) 2012-01-20 2019-10-29 Conformis, Inc. Devices, systems and methods for manufacturing orthopedic implants
US11419726B2 (en) 2012-01-20 2022-08-23 Conformis, Inc. Systems and methods for manufacturing, preparation and use of blanks in orthopedic implants
CN104780872A (en) * 2012-09-21 2015-07-15 康复米斯公司 Methods and systems for optimizing design and manufacture of implant components using solid freeform fabrication
CN104780872B (en) * 2012-09-21 2017-04-05 康复米斯公司 The method and system of the design and manufacture of optimization implant component is manufactured using free entity
US9849019B2 (en) 2012-09-21 2017-12-26 Conformis, Inc. Methods and systems for optimizing design and manufacture of implant components using solid freeform fabrication
US9681956B2 (en) 2013-01-30 2017-06-20 Conformis, Inc. Acquiring and utilizing kinematic information for patient-adapted implants, tools and surgical procedures
US9387083B2 (en) 2013-01-30 2016-07-12 Conformis, Inc. Acquiring and utilizing kinematic information for patient-adapted implants, tools and surgical procedures
CN103656760A (en) * 2013-12-09 2014-03-26 广西大学 Method for preparing individual porous thyroid cartilage support
CN103989541A (en) * 2014-05-19 2014-08-20 西安交通大学 Method for manufacturing high-strength composite bone and cartilage support with complex molded surface
CN103989541B (en) * 2014-05-19 2016-04-27 西安交通大学 There is the preparation method of the high strength composite bone cartilage frame of complex profile
CN108348340A (en) * 2015-09-30 2018-07-31 捷迈有限公司 Patient's particular instrument and method for patella surface prosthetic
US10874408B2 (en) 2015-09-30 2020-12-29 Zimmer, Inc Patient-specific instrumentation for patellar resurfacing surgery and method
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CN106725849A (en) * 2017-01-17 2017-05-31 武汉大学 A kind of fast conversion method of operation on mandible titanium plate osteotomy guide plate locus
CN110090100A (en) * 2019-05-31 2019-08-06 攀枝花学院 The 3D printing production method of arm fracture fixing apparatus and arm fracture fixing apparatus

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