CN1444031A - Full-automatic miniature bio-chemical analysis sample chamber - Google Patents

Full-automatic miniature bio-chemical analysis sample chamber Download PDF

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Publication number
CN1444031A
CN1444031A CN 03117657 CN03117657A CN1444031A CN 1444031 A CN1444031 A CN 1444031A CN 03117657 CN03117657 CN 03117657 CN 03117657 A CN03117657 A CN 03117657A CN 1444031 A CN1444031 A CN 1444031A
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CN
China
Prior art keywords
sample
full
lenticule
control system
sample chamber
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Pending
Application number
CN 03117657
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Chinese (zh)
Inventor
温志渝
陈刚
温中泉
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Chongqing University
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Chongqing University
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Publication date
Application filed by Chongqing University filed Critical Chongqing University
Priority to CN 03117657 priority Critical patent/CN1444031A/en
Publication of CN1444031A publication Critical patent/CN1444031A/en
Pending legal-status Critical Current

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Abstract

The present invention relates to a fully-automatic miniature bio-chemical analysis sample chamber, it is formed from lighting system, sample control system, temperature control system and optical coupling system, and integrally placed in a shell body, in which the sample control system includes a sample cell and a micropump, said micropump is connected with sample cell by means of inlet pipe and outlet pipe for making dynamic sample addition, the temperature control system is formed from semiconductor temperature regulator and temperature control circuit, and is positioned nearby sample cell for implementing constant temperature of sample cell. The invention can be matched with existent fiber-optical spectrograph, and can be extensively used in several fields of bio-chemistry, clinical medicine and others.

Description

Full-automatic miniature biochemical analysis sample chamber
Technical field
The invention belongs to technical field of analytical instruments, particularly relate to a kind of full-automatic miniature biochemical analysis sample chamber.
Background technology
In the prior art, the used sample chamber of micro fiber spectrometer does not have constant temperature system, and conventional sample chamber does not have the function of dynamic replacing sample yet.Can not solve the biochemistry detection that some need constant temperature, and owing to can't dynamically change sample, thereby can't carry out real-time detection the detected object that material composition and content of material change at any time.
Summary of the invention
The full-automatic miniature biochemical analysis sample chamber that a kind of constant temperature, amount of samples are few, cost is low that provides is provided at the deficiencies in the prior art.
The present invention comes to be realized by the following technical programs: full-automatic miniature biochemical analysis sample chamber, and it is made of illuminator, sample control system, optically coupled system, and integral body places in the shell.Wherein the sample control system comprises sample cell, Micropump, and Micropump connects sample cell by the turnover pipeline, and sample is implemented dynamic sample introduction.
The present invention also is provided with temperature control system, is made up of conductor temperature regulator and temperature control circuit, is positioned near the sample cell, realizes the constant temperature of sample cell.
Optically coupled system of the present invention comprise be positioned on the light path and be positioned at sample cell after lenticule and by its optical fiber that picks out, the output light of optical fiber can detect for the absorption spectrum that fiber spectrometer carry out material.
Illuminator of the present invention comprises concave mirror, light source and lenticule, and light source is between concave mirror and lenticule.Further improve under the situation of pale pinkish purple efficient at need, collimation lens, convergent lens can also also be set behind light source, again lenticule be set and connect another lenticule by optical fiber.Owing in native system, adopted micro-optical component, therefore the volume of total system reduced greatly.Make also corresponding the reducing of the amount of getting of required detection material simultaneously.
Adopt the technical program, can realize of the full-automatic dynamically replacing of biochemical spectral analysis sample chamber to sample, it has characteristics such as volume is little, constant temperature, amount of samples is few, cost is low, can be supporting with existing fiber spectrometer, be widely used in various fields such as biological chemistry, clinical medicine, legal medical expert's criminal investigation, environmental science, modern field operations and national defence.
Description of drawings
Fig. 1 is a structural representation of the present invention;
Fig. 2 is the configuration diagram of another embodiment of the present invention.
Embodiment
The shown component names of accompanying drawing is as follows: 1, concave mirror 2, light source 3, lenticule 4, sample cell 5, Micropump 6, lenticule 7, optical fiber 8, conductor temperature regulator 9, temperature control circuit 10, shell 11, collimation lens 12, convergent lens 13, lenticule 14, optical fiber
Embodiment 1: as shown in Figure 1, concave mirror 1 among the present invention, light source 2, lenticule 3 constitute illuminators, be positioned at sample cell 4 before.Sample cell 4, Micropump 5 constitute the sample control system, and Micropump connects sample cell by the turnover pipeline.Lenticule 6, optical fiber 7 are formed optically coupled system, the output light signal.The temperature control system that is made of conductor temperature regulator 8, temperature control circuit 9 is set near sample cell 4.Above-mentioned all parts all are arranged in the sample chamber shell 10.Its principle of work is as follows: the light that sends by light source 2 through concave mirror 1 reflection after, by becoming parallel beam behind lenticule 3 collimations, after the absorption of sample in this parallel beam process sample cell 4, be coupled in the optical fiber 7 by lenticule 6, the output light of optical fiber 7 can carry out the absorption spectrum detection of material for fiber spectrometer.In testing process, can implement dynamic sample introduction, and start temperature control circuit 9 control conductor temperature regulators 8, realize the constant temperature of sample cell by 5 pairs of samples of Micropump.
Embodiment 2, referring to Fig. 2, in this example, are to have added a kind of element that is used for optically-coupled before lenticule 3, comprise collimation lens 11, convergent lens 12, lenticule 13 and optical fiber 14.The light that is sent by light source 1 luminous energy becomes directional light through collimating mirror 10, is converging on the lenticule 12 by converging mirror 11, and is being coupled into optical fiber 13 by lenticule 12, and lenticule 3 will enter sample cell 4 behind the optical alignment of optical fiber 13 outgoing.This design can improve the efficient of optically-coupled greatly.

Claims (5)

1, a kind of full-automatic miniature biochemical analysis sample chamber, it is made of illuminator, sample control system, optically coupled system, integral body places in the shell (10), it is characterized in that the sample control system comprises sample cell (4), Micropump (5), Micropump (5) connects sample cell (4) by the turnover pipeline.
2, full-automatic miniature biochemical analysis according to claim 1 sample chamber is characterized in that it also is provided with temperature control system, is made up of conductor temperature regulator (8) and temperature control circuit (9).
3, full-automatic miniature biochemical analysis according to claim 1 and 2 sample chamber, it is characterized in that optically coupled system comprise be positioned on the light path and be positioned at sample cell after lenticule (6) and by its optical fiber that picks out (7).
4, full-automatic miniature biochemical analysis according to claim 1 and 2 sample chamber is characterized in that illuminator comprises concave mirror (1), light source (2) and lenticule (3), and light source (2) is positioned between concave mirror (1) and the lenticule (3).
5, full-automatic miniature biochemical analysis according to claim 4 sample chamber is characterized in that also being provided with collimation lens (11), convergent lens (12) behind the light source (2), again lenticule (13) is set and connects another lenticule (3) by optical fiber (14).
CN 03117657 2003-04-09 2003-04-09 Full-automatic miniature bio-chemical analysis sample chamber Pending CN1444031A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 03117657 CN1444031A (en) 2003-04-09 2003-04-09 Full-automatic miniature bio-chemical analysis sample chamber

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 03117657 CN1444031A (en) 2003-04-09 2003-04-09 Full-automatic miniature bio-chemical analysis sample chamber

Publications (1)

Publication Number Publication Date
CN1444031A true CN1444031A (en) 2003-09-24

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CN 03117657 Pending CN1444031A (en) 2003-04-09 2003-04-09 Full-automatic miniature bio-chemical analysis sample chamber

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CN (1) CN1444031A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100373151C (en) * 2005-01-13 2008-03-05 上海众毅工业控制技术有限公司 Laser Raman sample pool for gas analysis
CN102175607A (en) * 2011-01-19 2011-09-07 重庆大学 Small-sized multifunctional sample detection room
CN102866110A (en) * 2012-09-13 2013-01-09 北京利德曼生化股份有限公司 Biochemical analyzer optical system with reflection collecting lens
CN105121019A (en) * 2013-03-15 2015-12-02 伊鲁米那股份有限公司 System and method for generating or analyzing a biological sample
CN106443075A (en) * 2016-12-09 2017-02-22 南京大学 Temperature control system and temperature control sample stage for atomic force microscope
CN108225917A (en) * 2018-01-18 2018-06-29 重庆大学 A kind of adjustable two-way synchronous compression experiment home position observation device of ratio

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100373151C (en) * 2005-01-13 2008-03-05 上海众毅工业控制技术有限公司 Laser Raman sample pool for gas analysis
CN102175607A (en) * 2011-01-19 2011-09-07 重庆大学 Small-sized multifunctional sample detection room
CN102175607B (en) * 2011-01-19 2012-07-25 重庆大学 Small-sized multifunctional sample detection room
CN102866110A (en) * 2012-09-13 2013-01-09 北京利德曼生化股份有限公司 Biochemical analyzer optical system with reflection collecting lens
CN105121019A (en) * 2013-03-15 2015-12-02 伊鲁米那股份有限公司 System and method for generating or analyzing a biological sample
CN106443075A (en) * 2016-12-09 2017-02-22 南京大学 Temperature control system and temperature control sample stage for atomic force microscope
CN108225917A (en) * 2018-01-18 2018-06-29 重庆大学 A kind of adjustable two-way synchronous compression experiment home position observation device of ratio

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