CN1442149A - External use film forming powder for eliminating wound surface inflammation - Google Patents

External use film forming powder for eliminating wound surface inflammation Download PDF

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Publication number
CN1442149A
CN1442149A CN 03112124 CN03112124A CN1442149A CN 1442149 A CN1442149 A CN 1442149A CN 03112124 CN03112124 CN 03112124 CN 03112124 A CN03112124 A CN 03112124A CN 1442149 A CN1442149 A CN 1442149A
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CN
China
Prior art keywords
film forming
water
forming powder
wound
wound surface
Prior art date
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Pending
Application number
CN 03112124
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Chinese (zh)
Inventor
陈延龙
张瑞琛
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Individual
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Individual
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Publication date
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Priority to CN 03112124 priority Critical patent/CN1442149A/en
Publication of CN1442149A publication Critical patent/CN1442149A/en
Pending legal-status Critical Current

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Abstract

An inflammation-relieving filming powder for injury wound contains polyvinyl pyrrolidone iodine (0.5-10 wt. portions) and water-soluble chitosan (10-300 portions). Its advantage is high healing speed.

Description

Wound wound surface antiinflammatory film forming powder
Technical field
The present invention relates to wound wound surface antiinflammatory film forming powder compound formulation technical field.
Background technology
At present, be used for the medicine of traumatic surface antiinflammatory clinically, all exist and to form protecting film and to cause the problem that antibacterial efficacy is relatively poor, healing speed is slower wound surface.
Clinically, povidon iodine is the complex that polyethylene adjoins pyrrolidone and iodine, it is macromolecule carrier medicament, it separates out iodine in water, maybe when touching skin or mucosa, can decompose the effect that slowly discharges iodine and play sterilization and killing microorganisms gradually, have efficient and broad-spectrum bactericidal action, antibacterial, fungus and virus are all had the very strong ability of killing and Disinfection Effect.
Clinical research proves that water-soluble chitosan promotes that wound healing effect is better.Water-soluble chitosan contact and protection wound can form a skim; have good oxygen permeability, strong absorptive and slow enzyme (lysozyme) degradability etc.; it has following characteristics: one, good moisture-absorbing moisture-keeping function; keeping humidity of skin is the most basic condition that makes skin regeneration, and contains a plurality of hydrophilic group in the molecule of water-soluble chitosan, and molecule space is big; can be in conjunction with a large amount of moisture content; water absorption, water-retaining property are all very strong, and have high viscosity, permeability and lubrication.Two, good anti-inflammation is arranged, kill the function of pathogenic bacterium, can prevent to produce dermatosis.Contain in the chitinous molecular structure amido (--NH2) group, it has bactericidal action, again the Acidity of Aikalinity of scalable skin surface.The normal pH value of blood is 7.3, is acid in case reduce, and then is pursued by countless ailments and afflictions.And chitinous pH value is 7.4, and just in time the tart body fluid pH value of adjustable band moves to alkalescence.Chitin can suppress or kill many harmful pathogen.Three, filming performance is good: water-soluble chitosan dissolves in weak acid, CM-CT, and the CM-CTS water soluble forms viscous liquid.This liquid and skin, hair have stronger affinity and form film, and its film does not have rejection, and permeability is good, and is transparent, smooth, and can prevent dust, antistatic, easy cleaning, biodegradable, absorb.Four, have reproducibility, prevent skin oxidation and aging, chitin molecule, have amido (--NH2) group, can block the injury of radical pair Skin Cell, reduce the generation of lipid peroxide, reduce the deposition of pigment, it is white, healthy to help skin, the aging course of delaying skin.
Summary of the invention
The purpose of this invention is to provide a kind of wound wound surface antiinflammatory film forming powder compound formulation, it can solve prior art and exist and can't form protecting film and cause the problem that antibacterial efficacy is relatively poor, healing speed is slower wound surface.
The objective of the invention is to be achieved through the following technical solutions: wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 0.1-10 water-soluble chitosan 10-300
For further realizing also being achieved through the following technical solutions purpose of the present invention: described wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 0.4-9 water-soluble chitosan 20-250
Described wound wound surface antiinflammatory film forming powder, it comprises that following component is (with weight 0.9-1.2
Povidon iodine 0.8-8 water-soluble chitosan 40-200
Described wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 1.5-7.5 water-soluble chitosan 50-180
Described wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 2-7 water-soluble chitosan 60-160
Described wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 3-7 water-soluble chitosan 70-130
Described wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 3.5-6.5 water-soluble chitosan 80-120
Described wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 4-6 water-soluble chitosan 90-105
Described wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 4.5-5.5 water-soluble chitosan 90-99
Described wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 5 water-soluble chitosans 95
The beneficial effect that the present invention can produce: because of it by being micropowder with povidon iodine and water-soluble chitosan scientific composition; the povidon iodine molecular energy is entrenched in the aqueous chitosan molecule structure; it not only can suppress traumatic surface and infect; and can on traumatic surface, form protecting film rapidly simultaneously to prevent traumatic infection; improve the antibacterial efficacy of povidon iodine greatly with this, and quickened the healing of wound surface greatly.The present invention is widely used in the clinical burn wound etc. that can externally injure curative effect preferably.
The specific embodiment
Embodiment 1
Get povidon iodine 1Kg water-soluble chitosan 120Kg
The mixing pack after the known technology micronization is pulverized of above-mentioned prescription gets final product.
Embodiment 2
Get povidon iodine 3Kg water-soluble chitosan 70Kg
The mixing pack after the known technology micronization is pulverized of above-mentioned prescription gets final product.
Embodiment 3
Getting the mixing pack after the known technology micronization is pulverized of the above-mentioned prescription of povidon iodine 5Kg water-soluble chitosan 95Kg gets final product.
The technology that the present invention does not describe in detail partly is known technology.

Claims (10)

1, wound wound surface antiinflammatory film forming powder, it comprises following component (in weight portion):
Povidon iodine 0.1-10 water-soluble chitosan 10-300
2, wound according to claim 1 wound surface antiinflammatory film forming powder, it is characterized in that: it comprises following component (in weight portion):
Povidon iodine 0.4-9 water-soluble chitosan 20-250
3, wound according to claim 1 wound surface antiinflammatory film forming powder, it is characterized in that: it comprises following component (in weight portion):
Povidon iodine 0.8-8 water-soluble chitosan 40-200
4, wound according to claim 1 wound surface antiinflammatory film forming powder, it is characterized in that: it comprises following component (in weight portion):
Povidon iodine 1.5-7.5 water-soluble chitosan 50-180
5, wound according to claim 1 wound surface antiinflammatory film forming powder, it is characterized in that: it comprises following component (in weight portion):
Povidon iodine 2-7 water-soluble chitosan 60-160
6, wound according to claim 1 wound surface antiinflammatory film forming powder, it is characterized in that: it comprises following component (in weight portion):
Povidon iodine 3-7 water-soluble chitosan 70-130
7, wound according to claim 1 wound surface antiinflammatory film forming powder, it is characterized in that: it comprises following component (in weight portion):
Povidon iodine 3.5-6.5 water-soluble chitosan 80-120
8, wound according to claim 1 wound surface antiinflammatory film forming powder, it is characterized in that: it comprises following component (in weight portion):
Povidon iodine 4-6 water-soluble chitosan 90-105
9, wound according to claim 1 wound surface antiinflammatory film forming powder, it is characterized in that: it comprises following component (in weight portion):
Povidon iodine 4.5-5.5 water-soluble chitosan 90-99
10, wound according to claim 1 wound surface antiinflammatory film forming powder, it is characterized in that: it comprises following component (in weight portion):
Povidon iodine 5 water-soluble chitosans 95
CN 03112124 2003-04-09 2003-04-09 External use film forming powder for eliminating wound surface inflammation Pending CN1442149A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 03112124 CN1442149A (en) 2003-04-09 2003-04-09 External use film forming powder for eliminating wound surface inflammation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 03112124 CN1442149A (en) 2003-04-09 2003-04-09 External use film forming powder for eliminating wound surface inflammation

Publications (1)

Publication Number Publication Date
CN1442149A true CN1442149A (en) 2003-09-17

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 03112124 Pending CN1442149A (en) 2003-04-09 2003-04-09 External use film forming powder for eliminating wound surface inflammation

Country Status (1)

Country Link
CN (1) CN1442149A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100353932C (en) * 2004-03-22 2007-12-12 集美大学 Composite type superoxide anion free radical scavenger and its preparation method
CN105560271A (en) * 2016-03-04 2016-05-11 深圳市阳光百度生物科技发展有限公司 Chitosan povidone-iodine solution and manufacturing technologythereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100353932C (en) * 2004-03-22 2007-12-12 集美大学 Composite type superoxide anion free radical scavenger and its preparation method
CN105560271A (en) * 2016-03-04 2016-05-11 深圳市阳光百度生物科技发展有限公司 Chitosan povidone-iodine solution and manufacturing technologythereof

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