CN1442111A - High resolution detecting system for detecting finger tip pulse wave by photoelectric detecting frequency spectrum method - Google Patents
High resolution detecting system for detecting finger tip pulse wave by photoelectric detecting frequency spectrum method Download PDFInfo
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- CN1442111A CN1442111A CN03119646A CN03119646A CN1442111A CN 1442111 A CN1442111 A CN 1442111A CN 03119646 A CN03119646 A CN 03119646A CN 03119646 A CN03119646 A CN 03119646A CN 1442111 A CN1442111 A CN 1442111A
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Abstract
A high-resolution finger-end pulse wave detecting system with photoelectric detection and spectrum analysis has a probe containing two types of LEDs as light source, a photoelectric diodes as detecting element and a detecting host circuit composed of system amplifier circuit and data acquisition circuit. When a finger is positioned between light source and detector, the pulse wave signals are acquired under the control of computer and the data is analyzed by the spectrum analysis method.
Description
Affiliated field:
The invention belongs to the medical physics field, relate to a kind of instrument that detects and analyze physiological parameter.
Background technology:
Contain a large amount of useful informations in the human pulse ripple about human health status.The define method of pulse wave characteristic quantity has a variety of, for example uses the parameter of K value as pulse wave, is exactly a kind of effective define method.Referring to Fig. 1,
The definition of K value is as follows:
(Pn is the maximum of waveform in the formula, and Pd is the minimum of waveform, the DC component of Pm waveform.)
K value size has reflected human vas wall elasticity quality and Peripheral resistance size.Along with people's age, cardiovascular situation difference, the K value can change, generally between 0.3-0.5.
Detecting the direct or indirect method of pulse wave mainly contains following several:
1. contact tonometry: the traditional Chinese medical science is felt the pulse and is just belonged to this method in essence.The pulse wave detector of design is simple in structure though simulation is felt the pulse, and capacity of resisting disturbance is very poor.Because the working pressure pick off is as probe, in measuring process, be subjected to the influence of limb motion easily, and the probe applied pressure can change the form of pulse wave, the precision of measurement and resolution are reduced greatly.
2. bridge measurement method: human body resistance will change in the pulse wave propagate process.With the brachium pontis of human body resistance, by the non-equilibrium voltage detecting pulse wave between the measuring bridge bridge circuit as electric bridge.This measuring method is subjected to the influence of external electromagnetic field and contact resistance very big, can only rely on good shielding condition to improve precision.The signal that obtains in the actual measurement is the stack of pulse wave signal and the human body other biological signal of telecommunication (as electrocardio) often.
3. laser or ultrasonic doppler measurements method: utilizing the Doppler effect movement velocity of perception hemocyte and blood vessel wall respectively, measure pulse wave indirectly, is the reasonable measuring method of a kind of effect; But need costliness, huge apparatus, general entity and individual are beyond affordability.
4. photoelectric measurement method: according to lambert-Bill (Lambert-Beer) rule, change the long-pending variation of reflection vessel cross-sections, measure pulse wave indirectly by the light intensity that sees through finger tip.This method physical image is clear, and equipment is simple, the precision height, and capacity of resisting disturbance is strong, is convenient to measure and extends to general family use.
Goal of the invention:
As fully visible, present pulse wave detector often exists that poor anti jamming capability, resolution are low, the shortcoming of data poor repeatability, therefore stress the measurement of arteries and veins rule mostly, or have only the blood oxygen saturation of measurement individual event function, thereby limited the application of this outstanding medical measurement method greatly.
The present invention is directed to the problems referred to above, Photoelectric Detection and frequency spectrum analysis method are adopted in design.Adopt the probe of particular design, use the photodiode detection signal.By data acquisition and amplification system, cooperate independently developed data collection and analysis software based on sound card.Adopt the method for spectrum analysis that pulse wave is carried out high resolution detection and processing.When extracting fingertip pulse wave, can also measure this important physical parameter of blood oxygen saturation.The technical scheme of invention:
The detection system of the present invention's design comprises probe, detects main frame, computer (notebook or desk computer).One of built-in computer sound card comprises the special-purpose software that signal is handled simultaneously.
1. pop one's head in: adopt the transmission-type photoelectric detecting method, as light source, photodiode is done detector with two kinds of light emitting diodes, during measurement finger is placed in the middle of light source and the detector.The frame for movement of probe mainly is made up of light source, detector, base and regulating shaft, this four part of outer housing referring to Fig. 2.Main body adopts aluminum, and base adopts copper product, and the connection between the each several part is all finished by standard screw, nut.Detector adopts the related PIN photodiode of Chinese invention patent application 01123428.8.Light source, the detector of probe distribute referring to Fig. 3, and wherein Fig. 3 (a) is the Lights section, is made of the explorer portion that Fig. 3 (b) is made up of photodiode (PD) and protective cover thereof HONGGUANG and each two of two kinds of light emitting diodes of infrared light (LED).
Structure and effect to each several part is respectively described below below:
A. the Lights section [1]: effect is fixing required light source.Its primary structure is a groove [15], in order to the fixing wiring board of corresponding size [17], and leaves electric wire in the bottom portion of groove design and connects the hole, to introduce soldered wires.Can add the light emitting diode of various different capacities, different wave length, different arrangement modes by actual needs in the circuit board, constitute required light source; Fixing between wiring board and the groove by standard screw [9].
B. explorer portion [2]: effect is fixing required detector.Primary structure also is the wiring board [14] that embeds corresponding size by groove [16], and the while welds detector [2] in the circuit board and forms.Have not together with the Lights section; consider the life-span that prolongs detector; finger and detector surface repeated friction when avoiding measuring are simultaneously in order to reduce noise and because the influence that human body limb movement causes, the present invention has designed a detector protective cover [13] double as diaphragm.Fixing between protective cover, wiring board and the groove is also fixing by standard screw [9].The distribution of light source and detector is referring to Fig. 3, and Fig. 3 (a) is the Lights section, is made up of HONGGUANG and each two of two kinds of light emitting diodes of infrared light (LED); Fig. 3 (b) is an explorer portion, is made up of photodiode (PD) and protective cover double as diaphragm (DIA) thereof.Protective cover is above photodiode.
C. base and regulating shaft part: being the skeleton of whole probe apparatus, also is the core that connects each several part, simultaneously whole device has been played fixation.[4] be the support foot of base, its quality is relatively large, and this is in order to make whole probe stationary, to have satisfied this kind micrometering amount simultaneously and required immobilized relatively specific (special) requirements.The regulating shaft that links to each other with base [5] is made by copper product, is designed to helicitic texture [12].Altitude mixture control nut [6], hold-down nut [7] and the spring [8] in addition that match with it simultaneously are to finish measuring the adjustment of main body and datum plane relative position.
D. cover part [3]: this part is not only protected the core of probe, has also shielded the extraneous veiling glare that influence test result simultaneously, and makes the integral body of popping one's head in more simply attractive in appearance.The assembling of each several part is as shown in the figure:
A. at first will test required light source [1] and detector [2] is welded on the light source wiring board [17] and detector lines plate [14] that is complementary with the design size size;
B. utilize diagram standard screw [9] light source wiring board [17] to be fixed among the groove [15] of the Lights section;
C. utilize diagram standard screw [9] that protective cover [13] is fixed on the detector lines plate [14];
D. utilize diagram standard screw [9] detector lines plate [14] to be fixed among the groove [16] of explorer portion;
E. the wiring board lead-in wire is put in order, so that it does not influence next step assembling;
F. the Lights section is docked with explorer portion: the Lights section [15] is last, explorer portion [16] infra, and the two groove is relative, should make two parts carry out interlock according to the notch that designs during butt joint, so that the two reaches the fixed purpose of lucifuge after engaging;
The screw [6] of the vertical height of G. adjusting that indicates among the figure being popped one's head in is screwed on the regulating shaft [5] of base;
H. the order that installs according to light source and detector set, light source overlapped the hole heart of reserving the regulating shaft of base at last, detector infra;
I. spring [8] was overlapped the regulating shaft [5] of base;
J. hold-down nut [7] is screwed in the top of base regulating shaft;
K. anticreep screw [10] is screwed in light source and detector association side chute place, so that the two is unlikely to separately; Note not twisting tension, should leave certain adjusting space;
L. outer housing [3] is overlapped on the probe of finishing in front, and as shown in the figure, be fixed on the probe with fixed screw [11].
2. detection host circuit: comprise system's amplifying circuit and data acquisition circuit two parts.Wherein data acquisition circuit adopts the data collecting system based on computer sound card; System's amplifying circuit is made up of low pass filter, 2000 multiple proportions example amplifying circuit, peaker circuit, data acquisition circuit etc.The circuit block diagram of detection system is referring to Fig. 4, and P is a probe circuit, and L.P is a low pass filter, and M.A is a main amplifier, and A.A is a booster amplifier, and D.A is a data collecting system, and W is an oscillograph, and C is a computer, and D is the differential control circuit.
(1) low pass filter: adopt the active voltage-controlled low pass filter of second order, core parts are OP07 integrated operational amplifiers, and by 10 hertz of frequencies, Q-value is 20～30.
(2) main amplifier: core is 2000 multiple proportions examples operational amplifiers, is made up of two OP07 integrated circuits, cooperates some peripheral circuits, finishes master to the signal work of knocking off.Because amplification is very big, forms self-oscillation easily, can add negative feedback shunt capacitance weakening shake.
(3) booster amplifier: the scale operation amplifier of increase in order to adapt to the different measuring position, amplification is adjustable.When general measure, amplification can be adjusted to 1; When the weak signal position is measured, then amplification can be strengthened.
(4) differential control circuit: in pulse wave monitoring system in the past,, generally all be to adopt the method for gathering post processing earlier because the artifact that human motion produces is an open question for a long time.Because the motion artifact signal is sometimes than the big manyfold of primary signal,, make the acquisition system cisco unity malfunction to such an extent as to exceed acquisition range.Therefore we adopt the differential control circuit, with peaker pseudo-difference signal are highlighted earlier, pass through the low-pass filtering elimination again.
(5) data acquisition circuit: adopt the related data collecting system of Chinese invention patent application 03100490.3 based on computer sound card.Its ultimate principle is processing such as the very low signal of frequency that sound card can not directly be gathered generates through copped wave, double-side band and waveform is compound, becomes AC signal completely, is very easily with the such signal of sound card collection.
3. software section: be integrated with functional modules such as data acquisition, analysis, preservation, printing, utilize the means of spectrum analysis that pulse wave is handled, can measure the rhythm of the heart, K value and blood oxygen saturation.Beneficial effect:
The present invention can carry out the scientific research of relevant human pulse ripple for medical physics research department, can be used for Clinical detection, also can be used for family health care monitoring etc.This detection system has the following advantages:
1. resolution height can clearly reflect the nuance of pulse wave;
2. the employing photoelectric detection method is harmless to human body, and is simple;
3. detection sensitivity height, capacity of resisting disturbance is strong, the data good reproducibility;
4. adopt the data collecting system based on computer sound card, low price helps reducing cost;
5. measuring ability is strong, a tractor serves several purposes;
6. the instrument volume is little, can connect machine with notebook computer, and the scene of being easy to carry is detected.
Description of drawings:
Fig. 1 pulse wave K value implication sketch map
Fig. 2 frame for movement sketch map of popping one's head in
| The explanation of probe sketch map each several part | |||||
| ????1 | Light source | ????2 | Detector | ????3 | Outer housing |
| ????4 | The base support foot | ????5 | The altitude mixture control axle | ????6 | The altitude mixture control nut |
| ????7 | Hold-down nut | ????8 | Spring | ????9 | Standard screw (fixing) |
| ????10 | The anticreep screw | ????11 | The outer housing fixed screw | ????12 | The regulating shaft screw thread |
| ????13 | The detector protective cover | ????14 | The detector lines plate | ????15 | The Lights section groove |
| ????16 | The probe portion groove | ????17 | The light source wiring board | ||
Fig. 3 probe light source, detector distribution schematic diagram
Fig. 4 detects the host circuit block diagram
Fig. 5 complete machine pictorial diagram
Fig. 6 software interface figure
Fig. 7 experimental result picture---young student, the man, about 20 years old, healthy.
Fig. 8 experimental result picture---young student, the woman about 20 years old, suffered from myocarditis.
Fig. 9 experimental result picture---middle-aged male, one's mid-30s, healthy.
Figure 10 experimental result picture---elderly men is about 70 years old.
The same experimenter of Figure 11 experimental result picture---Fig. 9 measured at interval in one month once more
Embodiment:
When making probe, at first process the various piece of probe, combine then.The probe outer housing carries out black and sprays paint.Probe is inner to use the black sponge to fill, and plays lucifuge and buffered effect.In force, should note following some:
(1) Tan Tou the Lights section can be relative movable with explorer portion: the size according to tested person's finger is regulated automatically, is unlikely to too tight or too loose.Utilize probe self deadweight, make the optimum measurement state that reaches that contacts between finger and light source, the detector;
(2) vertical height of probe segment can be regulated: utilize the adjusting nut on the base regulating shaft, according to tested person's actual height, pushing, posture the height of probe is adjusted, mainly be to make tested person's measurement hands be in functional position, substantially loosen, such measurement result is scientific and effective more;
Should reduce moving of tested limbs when (3) measuring: because the particularity of measuring object requires the measured to remain static as far as possible as far as possible; Therefore the base of probe has certain mass, can firm preferably tested limbs.
(4) just can realize with common printed on both sides wiring board during circuit production.Integrated circuit can adopt OP07, and resistance adopts the carbon resistance of 1/16w, adopts the little metalfilmresistor of temperature coefficient individually.Electric capacity adopts general small-sized porcelain electric capacity to get final product.Transmission line adopts 4 core shielded cables.Power supply employing ± 12V power supply, no specific (special) requirements.
(5) during instrument testing, with the signal input part short circuit, the differential control circuit is shut, the amplification of auxiliary amplifying circuit is adjusted to 1, sinusoidal ac signal with 6 hertz of signal source generations, 10mv, begin debugging from final stage, making output signal is the sine wave of standard, and can't see till the tangible self-oscillation.Make the same parameter triangular wave then into,,, the instrument testing success is described if output also is sinusoidal wave substantially from the front end input.
When using this detection system to measure, the experimenter should keep health motionless as far as possible, calmly, and eupnea.Regulate the lifting bolt on the probe, make subject perception the most comfortable.Should regulate the amplification and the level that detect main frame, to adapt to the requirement of specific acquisition system.Acquisition time is got and was advisable in 20～30 seconds.
Actual measurement can be carried out according to the following steps:
(1) opens the on and off switch that detects main frame earlier, and be changed to the amplification of amplifier minimum.
(2) open computer again, move special-purpose monitoring system software.
(3) forefinger is put into probe, regulate amplification and waveform translation knob gradually, output signal is exaggerated in the acquisition range of acquisition system as much as possible, the signal that obtains like this, its resolving power is the highest.Loosen then, regulate the position of finger and the height of light source, till imperceptible compressing.Instrument is provided with external oscillograph monitor port, can external oscillograph to monitor wave form varies.
(4) configure acquisition time and sample rate, begin to gather (generally get and be advisable in 10 seconds to 20 seconds).If in gatherer process, finger has motion significantly, answers repeated acquisition.
(5) after collection finished, Automatic Program calculated the K value, the FFT conversion of the rhythm of the heart and waveform.
(6) preserve data, handle for later analysis.Several routine measurement reports are referring to experimental result picture:
(1) Fig. 7 is a young student, and the man is healthy about 20 years old, K=0.32, the rhythm of the heart=94.5;
(2) Fig. 8 is a young student, and the woman about 20 years old, suffered from myocarditis, K=0.55, the rhythm of the heart=56.0;
(3) Fig. 9 is a middle-aged male, and one's mid-30s is healthy, K=0.43, the rhythm of the heart=92.5;
(4) Figure 10 is an elderly men, about 70 years old, and K=0.53, the rhythm of the heart=78;
(5) Figure 11 and Fig. 9 are same experimenter, twice measurement one month at interval, and purpose is to carry out the repeatability check.
From measurement result as can be seen, many details compositions of pulse wave obviously embody, and repeatability is fine.
Claims (6)
1. fingertip pulse wave detection system, comprise probe, detect main frame, computer and software section, probe adopts the transmission-type photoelectric detecting method to detect the variation of fingertip pulse wave, it is characterized in that: the inner light emitting diode with two kinds of different wave lengths of probe is as light source, use photodiode to do detector, during measurement finger is placed in the middle of light source and the detector; Detect host circuit and comprise system's amplifying circuit and data acquisition circuit two parts; By the collection of computer control signal, use special-purpose software that image data is analyzed, utilize the means of spectrum analysis that pulse wave signal is handled.
2. the fingertip pulse wave detection system based on the Photoelectric Detection spectrum analysis according to claim 1 is characterized in that: probe mainly is made up of light source, detector, base and regulating shaft, outer housing four parts; The Lights section at groove upper fixed line road plate, welds light emitting diode by standard screw in the circuit board; Detector comprises photodiode and protective cover thereof; The cover part of probe has shielded extraneous veiling glare; Base plays fixed effect to whole device, and the regulating shaft that links to each other with base is a helicitic texture, adjusts measuring main body and datum plane relative position; The Lights section is last during connection, the explorer portion infra, and the two groove is relative, and two-part notch carries out interlock so that lucifuge during butt joint, on the probe that the outer housing cover is finished in front.
3. the fingertip pulse wave detection system based on the Photoelectric Detection spectrum analysis according to claim 2 is characterized in that: detector adopts the related PIN photodiode of Chinese invention patent application 01123428.8; Detector is provided with protective cover double as diaphragm, 1 centimetre of the aperture of the diaphragm; Protective cover is made with metal material, and both sides are screwed, and plays protection and shields interferential effect.
4. the fingertip pulse wave detection system based on the Photoelectric Detection spectrum analysis according to claim 1 is characterized in that: the signal amplification circuit that detects host circuit is made up of low pass filter, 2000 multiple proportions example amplifying circuit, peaker etc.; Wherein the core parts of low pass filter are OP07 integrated operational amplifiers; 2000 multiple proportions example operational amplifier is made up of two OP07 integrated circuits; The differential control circuit constitutes active differentiator by OP07, by with signal differentiation, gives prominence to the motion artifact signal, passes through low-pass filtering elimination artifact again.
5. the fingertip pulse wave detection system based on the Photoelectric Detection spectrum analysis according to claim 1 is characterized in that: the data acquisition circuit that detects host circuit partly adopts the related data collecting system based on computer sound card of Chinese invention patent application 03100490.3; Generate and processing such as waveform is compound by copped wave, double-side band, the very low signal of frequency that common sound card can not directly be gathered becomes the pure AC signal that sound card can be gathered; Its core parts are two CD4067 and 4 circuit that OP07 forms.
6. the fingertip pulse wave detection system based on the Photoelectric Detection spectrum analysis according to claim 1 is characterized in that: software section utilizes the means of spectrum analysis that pulse wave is handled, and measures the rhythm of the heart, pulse wave K value and oximetry value.
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| Application Number | Priority Date | Filing Date | Title |
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| CN031196462A CN1216567C (en) | 2003-03-19 | 2003-03-19 | High resolution detecting system for detecting finger tip pulse wave by photoelectric detecting frequency spectrum method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN031196462A CN1216567C (en) | 2003-03-19 | 2003-03-19 | High resolution detecting system for detecting finger tip pulse wave by photoelectric detecting frequency spectrum method |
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| CN1216567C CN1216567C (en) | 2005-08-31 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1317994C (en) * | 2004-05-21 | 2007-05-30 | 天津大学 | Time-domain light-deivisding differential wavelength spectro meter for detecting artery blood content and detection method thereof |
| CN1319487C (en) * | 2004-05-21 | 2007-06-06 | 天津大学 | Airspace light-diving differential wavelength spectro meter for detecting artery blood content and detection method thereof |
| CN101317756B (en) * | 2007-06-06 | 2010-12-01 | 索尼株式会社 | Apparatus for obtaining pulse bio-information and method thereof |
| CN102389299A (en) * | 2010-07-14 | 2012-03-28 | 罗姆股份有限公司 | Plethysmogram sensor |
-
2003
- 2003-03-19 CN CN031196462A patent/CN1216567C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1317994C (en) * | 2004-05-21 | 2007-05-30 | 天津大学 | Time-domain light-deivisding differential wavelength spectro meter for detecting artery blood content and detection method thereof |
| CN1319487C (en) * | 2004-05-21 | 2007-06-06 | 天津大学 | Airspace light-diving differential wavelength spectro meter for detecting artery blood content and detection method thereof |
| CN101317756B (en) * | 2007-06-06 | 2010-12-01 | 索尼株式会社 | Apparatus for obtaining pulse bio-information and method thereof |
| CN102389299A (en) * | 2010-07-14 | 2012-03-28 | 罗姆股份有限公司 | Plethysmogram sensor |
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| CN1216567C (en) | 2005-08-31 |
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