CN1372850A - Formula of body fluid supplementary liquid and preparation method thereof - Google Patents
Formula of body fluid supplementary liquid and preparation method thereof Download PDFInfo
- Publication number
- CN1372850A CN1372850A CN 01109064 CN01109064A CN1372850A CN 1372850 A CN1372850 A CN 1372850A CN 01109064 CN01109064 CN 01109064 CN 01109064 A CN01109064 A CN 01109064A CN 1372850 A CN1372850 A CN 1372850A
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- China
- Prior art keywords
- body fluid
- potassium
- supplementing liquid
- calcium
- sodium
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- 210000001124 body fluid Anatomy 0.000 title claims abstract description 57
- 239000010839 body fluid Substances 0.000 title claims abstract description 57
- 239000007788 liquid Substances 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 12
- 239000003792 electrolyte Substances 0.000 claims abstract description 12
- 239000011734 sodium Substances 0.000 claims abstract description 12
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 12
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000011575 calcium Substances 0.000 claims abstract description 9
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 9
- 150000001720 carbohydrates Chemical class 0.000 claims abstract description 6
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000011591 potassium Substances 0.000 claims abstract description 5
- 229910052700 potassium Inorganic materials 0.000 claims abstract description 5
- 239000000460 chlorine Substances 0.000 claims abstract description 4
- 229910052801 chlorine Inorganic materials 0.000 claims abstract description 4
- 150000003839 salts Chemical class 0.000 claims abstract 4
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims abstract 2
- 230000001502 supplementing effect Effects 0.000 claims description 26
- 230000018044 dehydration Effects 0.000 claims description 17
- 238000006297 dehydration reaction Methods 0.000 claims description 17
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 9
- 239000011780 sodium chloride Substances 0.000 claims description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 5
- 239000008103 glucose Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 229930091371 Fructose Natural products 0.000 claims description 4
- 239000005715 Fructose Substances 0.000 claims description 4
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 4
- 244000228451 Stevia rebaudiana Species 0.000 claims description 4
- 235000006092 Stevia rebaudiana Nutrition 0.000 claims description 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 4
- 229930006000 Sucrose Natural products 0.000 claims description 4
- 229960003975 potassium Drugs 0.000 claims description 4
- 239000005720 sucrose Substances 0.000 claims description 4
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 3
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 3
- CEYULKASIQJZGP-UHFFFAOYSA-L disodium;2-(carboxymethyl)-2-hydroxybutanedioate Chemical compound [Na+].[Na+].[O-]C(=O)CC(O)(C(=O)O)CC([O-])=O CEYULKASIQJZGP-UHFFFAOYSA-L 0.000 claims description 3
- 235000010241 potassium sorbate Nutrition 0.000 claims description 3
- 239000004302 potassium sorbate Substances 0.000 claims description 3
- 229940069338 potassium sorbate Drugs 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 239000001103 potassium chloride Substances 0.000 claims description 2
- 235000011164 potassium chloride Nutrition 0.000 claims description 2
- 239000001508 potassium citrate Substances 0.000 claims description 2
- 229960002635 potassium citrate Drugs 0.000 claims description 2
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 claims description 2
- 235000011082 potassium citrates Nutrition 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 claims description 2
- 239000000796 flavoring agent Substances 0.000 claims 3
- 235000019634 flavors Nutrition 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- KCROZBLSGFDMPS-UHFFFAOYSA-N [Ca].[Cl].[Na].[K] Chemical compound [Ca].[Cl].[Na].[K] KCROZBLSGFDMPS-UHFFFAOYSA-N 0.000 claims 2
- 235000013361 beverage Nutrition 0.000 claims 2
- 238000012163 sequencing technique Methods 0.000 claims 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- 235000015165 citric acid Nutrition 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 238000012859 sterile filling Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 25
- 230000000694 effects Effects 0.000 abstract description 5
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- 235000011194 food seasoning agent Nutrition 0.000 abstract 1
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- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 208000000112 Myalgia Diseases 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
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- 208000021760 high fever Diseases 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
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- 229910052760 oxygen Inorganic materials 0.000 description 2
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- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 2
- 235000010234 sodium benzoate Nutrition 0.000 description 2
- 239000004299 sodium benzoate Substances 0.000 description 2
- 235000011496 sports drink Nutrition 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
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- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 208000010444 Acidosis Diseases 0.000 description 1
- 208000009304 Acute Kidney Injury Diseases 0.000 description 1
- 102000004452 Arginase Human genes 0.000 description 1
- 108700024123 Arginases Proteins 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 206010059484 Haemodilution Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 206010022971 Iron Deficiencies Diseases 0.000 description 1
- WAEMQWOKJMHJLA-UHFFFAOYSA-N Manganese(2+) Chemical compound [Mn+2] WAEMQWOKJMHJLA-UHFFFAOYSA-N 0.000 description 1
- 206010027417 Metabolic acidosis Diseases 0.000 description 1
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- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
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- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 description 1
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- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a formula of a body fluid replenishing liquid and a preparation method thereof. The body fluid replenisher is prepared with the ratio of various main electrolytes in body fluid as reference standard, sodium, potassium, calcium and chlorine containing salt as main electrolyte, carbohydrate and seasoning as supplementary material and through scientific recipe. The body fluid replenisher can scientifically and safely replenish lost water and electrolyte for various people with water loss, thereby achieving the effects of health care and body building.
Description
Body fluid is not only the primary condition that life exists, and is the basic structure body of life structure.With regard to human, the part that constitutes our health is roughly as follows: protein accounts for 17%, and fat accounts for 14%, and carbohydrate accounts for 1.5%, mineral matters such as calcium account for 6%, and remaining 61.5% is body fluid, that is to say, 2/3 of body weight is a body fluid, and it is higher that the baby then contains body fluid volume, accounts for 80%.With regard to physiology, partes corporis humani's tissue is also mostly supported by body fluid.Human body we can say by body fluid and forms, vital movement even we can say with body fluid to be that media carries out, in case lack body fluid, life must finish.
Studies show that: various main electrolytical ratios are in the human plasma: sodium/potassium/calcium/chlorine=140/4/2.5/102; Various main electrolytical ratios are among the human sweat simultaneously: sodium/potassium/calcium/chlorine=130/3.5/2/110.This explanation human body has not only been lost a large amount of moisture content by perspire and has also been discharged various electrolyte in the human body fluid external.
The dehydration phenomenon that human body occurs can be divided three classes: hyperosmotic dehydration, hypotonic dehydration and isotonic dehydration.
1, the characteristics of hyperosmotic dehydration are that dehydration is greater than losing sodium.When hyperosmotic dehydration takes place animal, can feel thirsty, dehydration fever takes place in hypourocrinia, and the concentration of urine reduces, and the proportion that shows as urine reduces, and blood sodium and plasma protein concentration increase, and skin elasticity reduces, and metabolic acidosis might take place.Cause the reason of this dehydration generally to be: (1) subimbition; (2) a large amount of dehydrations and lose sodium (as vomiting, diarrhoea, high fever etc.) in a large number.Should note on the basis that keeps the skin wet, replenishing sodium and suitable potassium during treatment.
2, the characteristics of hypotonic dehydration are to lose sodium greater than dehydration.Such dehydration takes place, and the urine amount does not reduce at the beginning, and occur in brain and can cause that intracranial pressure raises, and with nervous symptoms, muscle weakness, slow in reacting, eyeball is recessed, skin is sent out wrinkle, generally lacks thirsty sense.Cause the reason of hypotonic dehydration to be: only to keep the skin wet after (1) massive blood loss, perspiration, vomiting, the diarrhoea and additional NaCl; (2) use thiazide diuretic for a long time, cause renal tubule that the heavily absorption of sodium is reduced.Treat very simply, replenish physiological saline and get final product, avoid additional glucose solution.
3, the characteristics of isotonic dehydration are that water and sodium equal proportion are lost.Show as blood pressure drops when serious, shock and acute renal failure change hyperosmotic dehydration into.Occurrence cause mainly also is that the digestive juice that vomiting, diarrhoea and intestinal obstruction cause is lost in a large number.Should import the electrolyte solution of low concentration during treatment.
Studies show that the moisture that human body replenishes will keep balance with the moisture that runs off.The major organs of human body loss moisture (also promptly needing the major organs of water): kidney: the 1-1.5L that daily urinates that is grown up, about baby 500mL; Lung: adult 250-350mL moisture is discharged by lung; Intestines: contain 75% moisture in the adult stool, with the moisture of stool discharge, every day about 100-200mL; Skin: the meeting loss large quantity of moisture of perspiring, the about 500mL of moisture that the adult is run off via skin; The digestion secretion: comprise pancreatic juice, gastric juice, saliva, intestinal juice, total amount is per day for adults " loss " 8L approximately, but it is gone back by the absorption of intestines wall most again.But if certain factors hamper this " again breathe " effect is arranged, diarrhoea for example then can be lost a large amount of intracellular fluids and caused serious dehydration.By the situation of water loss every day, human body can be extrapolated and at least daily 1800mL water need be replenished, about the about 1000mL of moisture that deduction food and food oxidation are produced, on average need to replenish the water of about 1000mL.But under diarrhoea or a large amount of situation of perspiring, can cause losing in a large number of body fluid.If the moisture that runs off reaches the 15-20% of body weight, physiological function just can stop.The child of one 10 kg body weight may lose a large amount of body fluid because of diarrhoea in the short time.Sportsman in contest also can lose a large amount of body fluid in the short time.At this moment, it is necessary replenishing sufficient body fluid.
The following principle of GPRS when replenishing body fluid: 1, yearningly can not be as unique sign of moisturizing, because when people feel thirsty, its water of losing has reached 2% of body weight; 2, all to replenish body fluid before, during and after the motion.3, can not mend pure water, can not mend the fruit juice of high concentration, and should replenish the body fluid supplementing liquid similar, thereby in order to avoid cause hemodilution to cause water intoxication to body fluid.
The formation that scientist has confirmed each element in the blood of human body is consistent with the formation of earth's crust interior element.This is will the chemical element in the surrounding environment to take in by drinking-water and food because of human body to participate in metabolism in the human body, makes interior chemical element of human body and the chemical element in the environment keep balance on a kind of ecology.The major physiological function of trace element in human body is: 1, play special active action in enzyme system.Some trace elements is the important component of plurality of enzymes in the body.In known enzyme, great majority all contain one or several metallic atom, and when losing trace meter in the enzyme molecule, the vigor of enzyme will be lost or descend; Again obtain these trace meters, it is normal that the vigor of enzyme just recovers.As the indispensable factor of vigor of enzyme, the still activator of enzyme that has.For example zinc ion can activate intestinal phosphatase enzyme and liver, kidney peroxidating ammonia enzyme, by insulin synthetic essential; Manganese ion can activate arginase, phosphatase, antelopeization enzyme and CHE etc.2, help hormone performance mediator body weight to want the effect of physiological function.3, common element is transported to whole body: trace elements iron is the important component of corpuscular hemoglobin, and hemoglobin takes oxygen in the histocyte to, just can not synthetic hemoglobin as iron deficiency, and oxygen just can't be carried, and histocyte just can not carry out eubolism.4, balance human body physiological function: trace element can be regulated osmotic pressure, ionic equilibrium and acid-base value in body fluid, to keep the human body normal physiological function.5, heredity: trace element can influence the metabolism of nucleic acid, and in experiment, scientist finds that vanadium, chromium, manganese, cobalt, copper, zinc, nickel etc. can influence the structure of the metabolism 6 of nucleic acid, participation vitamin: some trace element is the active part of vitamin.To we so important trace element have very major part need drink body fluid supplementing liquid to replenish.Now the pure water of selling on the market and many sports drinks can be in response to improper and cause water intoxication.
Discover, 65% to 70% of the about percentage of liveweight of water, and relatively stable in vivo.The cell membrane of human body cell is a pellicle, and water can free permeation, if drink is gone into a large amount of water, blood and interstitial fluid just replenish weighing apparatus and release, and osmotic pressure reduces, and water will be penetrated in the cell, makes cellular swelling and water intoxication takes place.Wherein the fastest with the brain cell reaction especially, in case cerebrocellular edema, the pressure of encephalic will increase, cause that dizzy brain rises, headache, vomiting, weak, eye-blurred, drowsiness, breathe slow down, the rhythm of the heart slows down, and then produces stupor, tic even threat to life when serious.During the generation water intoxication, excess moisture in the blood, the sodium chloride concentration in the blood descends, and the low blood sodium of the weighing apparatus property released occurs, and whole-body muscular pain or spasm appear in people's cognition.This phenomenon sportsman was often taken place in the latter half of match.
Water intoxication also often has generation in daily life, and just degree does not cause that gentlier people pay attention to.Especially during the broiling summer, after a large amount of perspirations of people, the electrolyte such as sodium salt in the body are also lost thereupon, do not supply salinity if drink plain boiled water this moment in a large number and jerk or muscle cramp pain will occur.The myalgia of arm, thigh and shank generally is the performance of slight water intoxication.Similar phenomenon usually takes place in the people of sportsman or participation vigorous exercise.
To carry out scientifically replenishing to body fluid.Now the pure water of selling on the market by elimination the water of many mineral matters and trace element, differ very big with the composition of body fluid.Replenishing body fluid with pure water does not only have benefit, can cause very big harm to health on the contrary.Many sports drinks, also the composition with body fluid differs greatly, and body fluid selects product for use as a supplement.
Purpose of the present invention will be invented a kind of body fluid supplementing liquid product exactly, the proportioning of its various electrolyte compositions is a normative reference with the various electrolyte proportionings of human body fluid, thereby can the science peace can replenish moisture content and the electrolyte of losing for various dehydration crowds in ground, thereby reach the effect of health body-building.
The people that body fluid supplementing liquid of the present invention is specially adapted to the sportsman or participates in vigorous exercise, not only can replenish because of the motion perspire and lose water and various main electrolyte because directly drink body fluid supplementing liquid of the present invention, and the jerk or the muscle cramp pain that occur in can preventing to move; Equally, body fluid supplementing liquid of the present invention also is specially adapted to because of various reasons (as acute diarrhea, high fever etc.) and the baby or the juvenile of dehydration, just can alleviate dehydration rapidly because directly drink body fluid supplementing liquid of the present invention, replenish the various main electrolyte lose, thereby avoided the misery brought because of transfusion.Simultaneously, very helpful to the dynamic equilibrium of keeping human body fluid because body fluid supplementing liquid of the present invention is to make with reference to the various electrolytical proportionings of human body fluid so it drinks not only safety but also science, thus also played the effect of health body-building.
The invention provides the example of following several body fluid supplementing liquid prescriptions:
Body fluid supplementing liquid prescription 1:
Prepare 1 liter of body fluid supplementing liquid, the addition of water and all cpds is as follows: pure water 966.4 grams, sodium chloride 2.11 grams, potassium citrate 1.9 grams, natrium citricum 0.64 gram, potassium sorbate 0.5 gram, calcium gluconae 0.45 gram, Sodium Benzoate 0.1 gram, glucose 20.5 grams, sucrose 15 grams, fructose 5.1 grams, citric acid 2 grams, STEVIA REBAUDIANA 0.1 gram.
Body fluid supplementing liquid prescription 2:
Prepare 1 liter of body fluid supplementing liquid, the addition of water and all cpds is as follows: pure water 964 grams, glucose 20.5 grams, sucrose 15 grams, fructose 5.1 grams, sodium chloride 3.5 grams, sodium acid carbonate 2.5 grams, citric acid 2 grams, potassium chloride 1.5 grams, STEVIA REBAUDIANA 0.1 gram, Sodium Benzoate 0.1 gram.
Details are as follows for body fluid supplementing liquid preparation method of the present invention:
The first step:,, successively join glucose, fructose, sucrose in the pure water according to the proportioning of above-mentioned body fluid supplementing liquid with being raw material through the strict pure water of handling;
Second step: after treating that above-mentioned three kinds of carbohydrate dissolve fully, successively add sodium chloride, natrium citricum, potassium sorbate, successively add calcium gluconae, STEVIA REBAUDIANA etc. then;
The 3rd step: after waiting whole compounds to dissolve fully, carry out filtration treatment;
The 4th step: adopt flash-sterilization method or the disinfection of high-temperature steam sterilization;
The 5th step: under aseptic condition, bottle.
Specify body fluid supplementing liquid of the present invention below in conjunction with Application Example:
Application Example one:
Three the repeatedly muscle cramp that latter half often occurs thigh and shank and pain of match that the football player is former.They do not know that to this be the performance of the water intoxication that causes owing to fluid infusion is improper.When these sportsmen had all drunk the body fluid supplementing liquid of being produced with body fluid supplementing liquid prescription 1 in pre-games and match after, they were in the muscle cramp and the pain that do not occur thigh and shank latter half again of match.
Application Example two:
Dewatering symptom has appearred in the children of 30 diarrhoea at second day that suffers from diarrhoea.These little patients behind the body fluid supplementing liquid of being produced with body fluid supplementing liquid prescription 2, he (she) all do not have to have eliminated the dehydration phenomenon through venous transfusion.
Claims (9)
1, a kind of body fluid supplementing liquid is characterized in that: with the various main electrolytical ratios of human body fluid is normative reference, is main electrolyte with the salt that contains sodium potassium calcium chlorine, is auxiliary material with carbohydrate and flavor enhancement, is mixed with through scientific formula to form.
2, the salt that contains sodium potassium calcium chlorine according to claim 1, it is characterized in that: it is a kind of mixture, wherein contains sodium chloride, potassium chloride, natrium citricum, potassium citrate, sodium acid carbonate, saleratus, calcium gluconae.
3, carbohydrate according to claim 1 is characterized in that: it is a kind of mixture, wherein contains glucose, fructose, sucrose, calcium gluconae, lactose, galactolipin.
4, flavor enhancement according to claim 1, it comprises following a kind of material at least: STEVIA REBAUDIANA, citric acid, potassium sorbate.
5, scientific formula according to claim 1 comprises the proportioning of various used main electrolyte and auxiliary material and it is joined the sequencing of vortex mixer.
6, the proportioning of various used main electrolytical molecular weight according to claim 5 is: sodium: potassium: calcium: chlorine=(130-150): (3-5): (2-3): (90-110).
7, the body fluid supplementing liquid of preparation indication of the present invention with the various raw materials used sequencings that join vortex mixer is: add carbohydrate earlier, add and contain main electrolytical salt, at last with flavor enhancement.
8, the body fluid supplementing liquid of preparation indication of the present invention behind various raw materials used mixings, can adopt normally used flash-sterilization method or high-temperature steam sterilization to handle, after sterile filling is made finished product.
9, body fluid supplementing liquid finished product according to claim 8 can be the body fluid supplementing liquid beverage that is used to prevent the sport type beverage that dewaters or is used for replenishing dehydration.
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|---|---|---|---|
| CN 01109064 CN1372850A (en) | 2001-02-28 | 2001-02-28 | Formula of body fluid supplementary liquid and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 01109064 CN1372850A (en) | 2001-02-28 | 2001-02-28 | Formula of body fluid supplementary liquid and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103535831A (en) * | 2013-10-22 | 2014-01-29 | 浙江小二黑食品有限公司 | Functional sports beverage |
| CN102824364B (en) * | 2012-08-15 | 2017-12-01 | 湖北凤凰白云山药业有限公司 | A kind of oral liquid of anti-dehydrating and its application |
-
2001
- 2001-02-28 CN CN 01109064 patent/CN1372850A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102824364B (en) * | 2012-08-15 | 2017-12-01 | 湖北凤凰白云山药业有限公司 | A kind of oral liquid of anti-dehydrating and its application |
| CN103535831A (en) * | 2013-10-22 | 2014-01-29 | 浙江小二黑食品有限公司 | Functional sports beverage |
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