CN1340331A - 钛表面修饰人工晶体的方法及其产品 - Google Patents
钛表面修饰人工晶体的方法及其产品 Download PDFInfo
- Publication number
- CN1340331A CN1340331A CN 00122851 CN00122851A CN1340331A CN 1340331 A CN1340331 A CN 1340331A CN 00122851 CN00122851 CN 00122851 CN 00122851 A CN00122851 A CN 00122851A CN 1340331 A CN1340331 A CN 1340331A
- Authority
- CN
- China
- Prior art keywords
- titanium
- intraocular lenses
- iol
- artificial
- artificial intraocular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000010936 titanium Substances 0.000 title claims abstract description 51
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 title claims abstract description 49
- 229910052719 titanium Inorganic materials 0.000 title claims abstract description 49
- 238000000034 method Methods 0.000 title claims abstract description 23
- 239000013078 crystal Substances 0.000 title claims abstract description 12
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 9
- 229910052786 argon Inorganic materials 0.000 claims abstract description 8
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 8
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 8
- 230000008021 deposition Effects 0.000 claims abstract description 7
- 238000010884 ion-beam technique Methods 0.000 claims abstract description 7
- 125000001153 fluoro group Chemical group F* 0.000 claims abstract description 6
- 125000004433 nitrogen atom Chemical group N* 0.000 claims abstract description 4
- 125000004430 oxygen atom Chemical group O* 0.000 claims abstract description 4
- 229910052751 metal Inorganic materials 0.000 claims description 9
- 239000002184 metal Substances 0.000 claims description 9
- 239000012528 membrane Substances 0.000 claims description 5
- 239000000956 alloy Substances 0.000 abstract description 5
- 229910045601 alloy Inorganic materials 0.000 abstract description 5
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 12
- 239000004926 polymethyl methacrylate Substances 0.000 description 12
- 239000007943 implant Substances 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 6
- 210000003714 granulocyte Anatomy 0.000 description 6
- 210000002540 macrophage Anatomy 0.000 description 6
- 229910052731 fluorine Inorganic materials 0.000 description 5
- 230000002980 postoperative effect Effects 0.000 description 5
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 4
- 210000002950 fibroblast Anatomy 0.000 description 4
- 229960002897 heparin Drugs 0.000 description 4
- 229920000669 heparin Polymers 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 230000009977 dual effect Effects 0.000 description 2
- 210000000871 endothelium corneal Anatomy 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000011737 fluorine Substances 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 206010023683 lagophthalmos Diseases 0.000 description 2
- 238000004445 quantitative analysis Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 208000005422 Foreign-Body reaction Diseases 0.000 description 1
- 241001062009 Indigofera Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 208000029091 Refraction disease Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 201000010814 Synostosis Diseases 0.000 description 1
- 102000004887 Transforming Growth Factor beta Human genes 0.000 description 1
- 108090001012 Transforming Growth Factor beta Proteins 0.000 description 1
- 102000009618 Transforming Growth Factors Human genes 0.000 description 1
- 108010009583 Transforming Growth Factors Proteins 0.000 description 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 1
- 206010046851 Uveitis Diseases 0.000 description 1
- 235000009392 Vitis Nutrition 0.000 description 1
- 241000219095 Vitis Species 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004430 ametropia Effects 0.000 description 1
- 210000002159 anterior chamber Anatomy 0.000 description 1
- 210000001742 aqueous humor Anatomy 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000005779 cell damage Effects 0.000 description 1
- 208000037887 cell injury Diseases 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 206010014801 endophthalmitis Diseases 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 230000003328 fibroblastic effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000003448 neutrophilic effect Effects 0.000 description 1
- 231100001083 no cytotoxicity Toxicity 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 208000014733 refractive error Diseases 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 102000003390 tumor necrosis factor Human genes 0.000 description 1
Images
Landscapes
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 00122851 CN1340331A (zh) | 2000-08-30 | 2000-08-30 | 钛表面修饰人工晶体的方法及其产品 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 00122851 CN1340331A (zh) | 2000-08-30 | 2000-08-30 | 钛表面修饰人工晶体的方法及其产品 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1340331A true CN1340331A (zh) | 2002-03-20 |
Family
ID=4589363
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 00122851 Pending CN1340331A (zh) | 2000-08-30 | 2000-08-30 | 钛表面修饰人工晶体的方法及其产品 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1340331A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100424225C (zh) * | 2004-03-04 | 2008-10-08 | 韩国原子力研究所 | 通过离子注入和热处理制备有色金刚石的方法 |
-
2000
- 2000-08-30 CN CN 00122851 patent/CN1340331A/zh active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100424225C (zh) * | 2004-03-04 | 2008-10-08 | 韩国原子力研究所 | 通过离子注入和热处理制备有色金刚石的方法 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4718905A (en) | Haptic element using ion beam implantation for an intraocular lens | |
Karesh et al. | High-density porous polyethylene (Medpor) as a successful anophthalmic socket implant | |
US7083646B2 (en) | Surface modification of functional group-containing intraocular lenses | |
Linnola | Sandwich theory: bioactivity-based explanation for posterior capsule opacification | |
CN1035822C (zh) | 可润湿的聚硅氧烷水凝胶组合物及它们的制备方法和用途 | |
EP2067453B1 (en) | Keratoprosthesis | |
RU2114579C1 (ru) | Протез для субэпителиальной имплантации | |
CN1101780A (zh) | 预防继发性白内障的方法和手段 | |
CN1246070A (zh) | 眼内透镜及一体型眼内透镜的制造方法 | |
Hicks et al. | Clinical results of implantation of the Chirila keratoprosthesis in rabbits | |
CN105879115A (zh) | 一种牙科种植体及其表面制备方法 | |
US8344042B2 (en) | Biodegradable synthetic bone composites | |
Caldwell | The soft keratoprosthesis. | |
US20210187161A1 (en) | Medical device comprising graphene coating | |
Buchen et al. | Assessing intraocular lens calcification in an animal model | |
CN210384490U (zh) | 一种骨缺损的修复装置 | |
CN107007879A (zh) | 一种活性人工角膜及其制备方法 | |
CN1181803C (zh) | 诱导成骨生物活性人工牙根种植体材料及其制备方法 | |
JPS63192438A (ja) | 経角膜移植用人工角膜およびその製造方法 | |
CN1340331A (zh) | 钛表面修饰人工晶体的方法及其产品 | |
WO1988002622A1 (en) | Collagen-hydrogel lens for promoting epithelial cell growth | |
CN111729130B (zh) | 一种生物抗污性能优异的人工晶状体涂层及其制备方法 | |
León et al. | Coralline hydroxyapatite keratoprosthesis in rabbits | |
Purdy | Oculoplastic and orbital applications of porous high-density polyethylene implants | |
CN110025402B (zh) | 含生物材料的人工角膜 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
ASS | Succession or assignment of patent right |
Owner name: TIANJIN TEDA BIOLOGY TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: GU HANQING Effective date: 20020628 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20020628 Address after: 300457 TEDA The Heart of Pai, Third Street, 16 economic and Technological Development Zone, Tianjin Applicant after: Tianjin TEDA biological Polytron Technologies Inc Address before: 300457 Tianjin City Fifth Street, economic and Technological Development Zone Taihua Road No. 12 7 floor Applicant before: Gu Hanqing |
|
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |