CN1327852A - Chinese medicine for treating coronary heart disease, reducing blood fat and improving sleep and its preparing process - Google Patents
Chinese medicine for treating coronary heart disease, reducing blood fat and improving sleep and its preparing process Download PDFInfo
- Publication number
- CN1327852A CN1327852A CN 01119823 CN01119823A CN1327852A CN 1327852 A CN1327852 A CN 1327852A CN 01119823 CN01119823 CN 01119823 CN 01119823 A CN01119823 A CN 01119823A CN 1327852 A CN1327852 A CN 1327852A
- Authority
- CN
- China
- Prior art keywords
- medicine
- heart disease
- coronary heart
- blood fat
- folium ginkgo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
A Chinese medicine for treating coronary heart disease, reducing blood fat and improving sleep is prepared from gingko leaf and ganoderma.
Description
The present invention relates to a kind of medicine for the treatment of coronary heart disease, blood fat reducing, improvement sleep, particularly relate to a kind of Chinese medicine and preparation method thereof with above-mentioned effect.
At present gingko leaf preparation is in pharmacy industry with health products trade is existing uses widely, and most of gingko leaf preparation is an one-component, and in the Folium Ginkgo extract general flavone content about 24%.Folium Ginkgo has good prospect in the treatment of numerous disease, the ginkgo leaf compound preparation that exploitation has blood fat reducing, improve sleep is still rare.
The object of the invention be to provide a kind of evident in efficacy, high Chinese medicine of Ginkgo total flavones content and preparation method thereof has no side effect.
Technical solution of the present invention is achieved in that
Folium Ginkgo 10-30 weight portions
Ganoderma 2-10 weight portions
With the above-mentioned raw materials medicine routinely technology make any acceptable drug clinically.The ginkgo leaf powder of material medicine can also be broken into coarse powder (crossing 20 mesh sieves), decoct three times with the aqueous solution that contains 1-2% antioxidant, each water consumption is 10-15 times, decocting time was respectively 1-2 hours, merge three times the decocting liquid medicinal liquid, by macroporous resin adsorption, adsorption column is with 50～90% alcohol desorptions, eluent reclaims ethanol, is condensed into thick paste; Ganoderma decocting in water three times, each 1 one 2 hours, medicinal liquid is merged, filters, is concentrated into thick paste, to mix with the Folium Ginkgo thick paste, spray drying is made clinical acceptable forms.
Antioxidant described in the inventive method can be sodium pyrosulfite, vitamin C or sodium sulfite; The antioxidant concentration of aqueous solution is 0.5%; The height of macroporous resin column and the ratio of diameter are 4 one 15.
Medicine of the present invention has the effect of treatment coronary heart disease, blood fat reducing, improvement sleep through laboratory observation.Experimental result shows that medicine of the present invention has coronary artery dilator, increases coronary flow, improves myocardial ischemia, reduces myocardial oxygen consumption, and blood lipid regulation reduces blood cholesterol levels, improves the effect of sleep quality;
Medicine of the present invention detects through effective component and shows, Ginkgo total flavones content＞20mg in the unit formulation of suitable crude drug 10g, and the state-promulgated pharmacopoeia standard only is＞9.6mg.
Embodiment 1: Folium Ginkgo 10kg, Ganoderma 2kg, clean, oven dry, pulverize (crossing 20 mesh sieves), decoct three times with the aqueous solution that contains 0.5% sodium pyrosulfite, each water consumption is respectively 12,10,10 times, decocting time was respectively 1,1.5,1.5 hour, merged three times decocting liquid, adsorbed by macroporous resin D101, the post height is 4 with the column diameter ratio, adsorption column 70% alcohol desorption, eluent reclaims ethanol, is condensed into thick paste; Ganoderma decocting in water three times was respectively 2,1,1 hours at every turn, and medicinal liquid is merged, filters, is concentrated into thick paste, mixed with the Folium Ginkgo thick paste, and spray drying is made capsule, every suitable crude drug 10g.Embodiment 2: Folium Ginkgo 10kg, and Ganoderma 5kg, Folium Ginkgo is pulverized, with containing 0.7% sodium sulfite decocting in water 3 times, the 1st time 1.5 hours, the 2nd, 3 time each 1 hour, 3 times water cooking liquid merged, and filters, filtrate is used 75% ethanol elution with macroporous adsorbent resin AB-8 absorption, and eluent reclaims ethanol, concentrates; Ganoderma is used decocting in water 3 times, and the 1st time 2 hours, the 2nd, 3 time each 1 hour.3 times decocting liquid merges, and filters, and filtrate is concentrated into thick paste, merge with above-mentioned Folium Ginkgo concentrated solution, and spray granulation, packing, every bag is equivalent to crude drug 10g.
Claims (7)
1, a kind of medicine for the treatment of coronary heart disease, blood fat reducing, improvement sleep is characterized in that this medicine made by following bulk drugs:
Folium Ginkgo 10-30 Ganodermas 2-10
2, medicine as claimed in claim 1 is characterized in that this medicine is by descending bulk drugs to make:
Folium Ginkgo 10 Ganodermas 5
3, a kind of preparation method for the treatment of the medicine of coronary heart disease, blood fat reducing, improvement sleep, it is characterized in that this method is: Folium Ginkgo coarse powder 10-30 weight portions, with the aqueous solution of 1-2% antioxidant of 10-15 times of amounts, respectively heated and boiled, stir and extract three times, each extraction time is 1-2 hours, remove medicinal residues, merge three times medicinal liquid, filter, filtrate is crossed macroporous adsorptive resins, use the triplication water washing, reuse 60-90% ethanol elution, eluent concentrates; Decocting in water three times of Ganoderma 2-10 weight portions, each extraction time is 1-2 hours, and collecting decoction filters, and filtrate is concentrated into thick paste, merges with above-mentioned Folium Ginkgo concentrated solution, and spray drying is made any clinical acceptable forms that contains suitable raw medicinal herbs 10g.
4, a kind of preparation method for the treatment of the medicine of coronary heart disease, blood fat reducing, improvement sleep as claimed in claim 3, it is characterized in that this method is: Folium Ginkgo coarse powder 10kg, aqueous solution with 1-0.7% antioxidant of 12 times of amounts, heated and boiled, stirring are extracted three times respectively, extraction time is 1 hour for the first time, it is 1.5 hours for the second time, be 1.5 hours for the third time, remove medicinal residues, merge three times medicinal liquid, filter, filtrate is crossed macroporous adsorptive resins, use the triplication water washing, reuse 70% ethanol elution, eluent concentrates; Ganoderma is used decocting in water three times, and each extraction time was respectively 2,1,1 hours, and collecting decoction filters, and filtrate is concentrated into thick paste, merges with above-mentioned Folium Ginkgo concentrated solution, and spray drying is made the capsule that contains suitable raw medicinal herbs 10g.
5, as claim 3 or 4 described a kind of preparation methoies for the treatment of the medicine of coronary heart disease, blood fat reducing, improvement sleep, it is characterized in that the antioxidant in this method can be sodium pyrosulfite, vitamin C or sodium sulfite; The antioxidant concentration of aqueous solution is 0.5%.
6, as claim 3 or 4 described a kind of preparation methoies for the treatment of the medicine of coronary heart disease, blood fat reducing, improvement sleep, it is characterized in that the height of the macroporous resin column in this method and the ratio of diameter are 4-15.
7, a kind of preparation method for the treatment of the medicine of coronary heart disease, blood fat reducing, improvement sleep as claimed in claim 6 is characterized in that the height of the macroporous resin column in this method and the ratio of diameter are 4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011198230A CN1161146C (en) | 2001-06-29 | 2001-06-29 | Chinese medicine for treating coronary heart disease, reducing blood fat and improving sleep and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011198230A CN1161146C (en) | 2001-06-29 | 2001-06-29 | Chinese medicine for treating coronary heart disease, reducing blood fat and improving sleep and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1327852A true CN1327852A (en) | 2001-12-26 |
| CN1161146C CN1161146C (en) | 2004-08-11 |
Family
ID=4663738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011198230A Expired - Fee Related CN1161146C (en) | 2001-06-29 | 2001-06-29 | Chinese medicine for treating coronary heart disease, reducing blood fat and improving sleep and its preparing process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1161146C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904891A (en) * | 2010-07-27 | 2010-12-08 | 成都天宇联盟医药科技有限责任公司 | Ginkgo leaf pills and preparation method thereof |
-
2001
- 2001-06-29 CN CNB011198230A patent/CN1161146C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904891A (en) * | 2010-07-27 | 2010-12-08 | 成都天宇联盟医药科技有限责任公司 | Ginkgo leaf pills and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1161146C (en) | 2004-08-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1292704A (en) | Ginkgo leaves composition and preparation method and uses | |
| CN102423352B (en) | Preparation method of Chinese medicinal granules for treating cardio-cerebrovascular diseases | |
| WO2011079410A1 (en) | Medicinal composition including sunflower extract, preparative method and use thereof | |
| CN1484529A (en) | Gusuibu extracts for trvating osteoporosis and method for extracting same | |
| KR101052574B1 (en) | Method for preparing an extract fraction with enhanced ginsenosides Rg1 or Rb1 from ginseng | |
| CN101716198B (en) | Method for preparing total ginkgo flavone glycosides slow-release capsules by applying attapulgite | |
| CN1161146C (en) | Chinese medicine for treating coronary heart disease, reducing blood fat and improving sleep and its preparing process | |
| CN103372034A (en) | Preparation method of ginkgo biloba extract | |
| CN1173724C (en) | Systemic separation process and prepn of ginkgetin, ginkgolide and bilobalide | |
| CN100444849C (en) | New use of tribulus terrestris extraction | |
| CN1058158C (en) | Single or compound preparation made from ginkgo leaf and plant contg. saponin for prevention and treatment of heart and brain vascular diseases | |
| CN102626427B (en) | Ginkgo dipyridamole composition and preparation method of preparation thereof | |
| CN1136004C (en) | Chinese medicine for relieving fatigue and resisting oxygen lack and its preparing process | |
| CN107468761B (en) | A kind of Preparation method and use of glossy privet fruit total triterpenic acid extract | |
| CN1297277C (en) | Laminaran granule and its preparation technology | |
| CN101015596A (en) | Chinese patent drug for curing angiocardiopathy and cerebrovascular disease and its preparing method | |
| CN111407836A (en) | A compound wine with blood pressure lowering, blood lipid reducing, and blood sugar lowering effects, and its preparation method | |
| CN102000126B (en) | Ginkgo flavone tablet and preparation method thereof | |
| CN108186773A (en) | A kind of Weight-lossing hypolipemic medicine preparation and preparation method thereof | |
| CN1080863A (en) | A kind of health medicine compositions of relieving the effect of alcohol | |
| CN1048875C (en) | Preparation method of instant powder for tracheitis | |
| CN1887309B (en) | Extraction of effective red sage components for preventing and treating osteoporosis and depression | |
| CN1695674A (en) | Health protection medicine of Chinese traditional medicine for decreasig high blood pressure and complicating disease and its prepn. method | |
| CN103977163B (en) | Medicinal composition with myocardial ischemia resisting effect, preparation method and application thereof | |
| CN101411778A (en) | Chinese medicine effective component composition and method for preparing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Sichuan Kechuang Medicine Group Co., Ltd. Assignor: Xinshiji Science and Technology Co., Ltd., Chengdu Contract record no.: 2010510000020 Denomination of invention: Chinese medicine for reducing blood fat and improving sleep and preparation method thereof Granted publication date: 20040811 License type: Exclusive License Open date: 20011226 Record date: 20100512 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20040811 Termination date: 20160629 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |