CN1326992C - 提高慢病毒感染的细胞培养物的细胞密度的组合物和方法 - Google Patents
提高慢病毒感染的细胞培养物的细胞密度的组合物和方法 Download PDFInfo
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- CN1326992C CN1326992C CNB028096002A CN02809600A CN1326992C CN 1326992 C CN1326992 C CN 1326992C CN B028096002 A CNB028096002 A CN B028096002A CN 02809600 A CN02809600 A CN 02809600A CN 1326992 C CN1326992 C CN 1326992C
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
实验组 | 抗生素浓度(μg/mL) | 第0天(细胞/mL) | 第1天 | 第2天 | 第3天 | 第4天 | 第 5天 |
对照 | N/A | 3.0×105 | 3.6×105 | 5.5×105 | 1.0×106 | 1.2×106 | 1.2× |
庆大霉素 | 30μg/mL | 3.0×105 | 2.4×105 | 3.2×105 | 6.5×105 | 1.1×106 | 1.1× |
新霉素 | 30μg/mL | 3.0×105 | 4.7×105 | 7.8×105 | 1.2×106 | 1.3×106 | 1.8× |
多粘菌素B | 30μg/mL | 3.0×105 | 2.9×105 | 4.6×105 | 5.8×105 | 6.6×105 | 6.6× |
多粘菌素 B+ 新霉素 | 30μg/mL+30μg/mL | 3.0×105 | 2.9×105 | 5.0×105 | 7.0×105 | 7.7×105 | 7.8× |
Claims (37)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29009601P | 2001-05-10 | 2001-05-10 | |
US60/290,096 | 2001-05-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1514734A CN1514734A (zh) | 2004-07-21 |
CN1326992C true CN1326992C (zh) | 2007-07-18 |
Family
ID=23114512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB028096002A Expired - Lifetime CN1326992C (zh) | 2001-05-10 | 2002-05-03 | 提高慢病毒感染的细胞培养物的细胞密度的组合物和方法 |
Country Status (25)
Country | Link |
---|---|
US (1) | US7160721B2 (zh) |
EP (2) | EP1385540B1 (zh) |
JP (1) | JP4283544B2 (zh) |
KR (1) | KR20040029981A (zh) |
CN (1) | CN1326992C (zh) |
AT (1) | ATE521364T1 (zh) |
AU (1) | AU2002342568B2 (zh) |
BG (1) | BG108315A (zh) |
BR (1) | BR0209482A (zh) |
CA (1) | CA2446131C (zh) |
CY (1) | CY1112123T1 (zh) |
CZ (1) | CZ20033046A3 (zh) |
DK (1) | DK1385540T3 (zh) |
ES (1) | ES2369846T3 (zh) |
HR (1) | HRP20030974A2 (zh) |
HU (1) | HUP0400283A2 (zh) |
MX (1) | MXPA03010208A (zh) |
NO (1) | NO20034961L (zh) |
NZ (1) | NZ529326A (zh) |
PL (1) | PL373847A1 (zh) |
PT (1) | PT1385540E (zh) |
SI (1) | SI1385540T1 (zh) |
WO (1) | WO2002091994A2 (zh) |
YU (1) | YU88703A (zh) |
ZA (1) | ZA200309556B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10920483B2 (en) | 2018-10-25 | 2021-02-16 | Mark Mutchnik | Window seal for preventing water penetration |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4215107A (en) * | 1978-12-29 | 1980-07-29 | Merck & Co., Inc. | Parainfluenza virus vaccine and its preparation |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57194787A (en) * | 1981-05-28 | 1982-11-30 | Ajinomoto Co Inc | Culture medium for animal cell |
US6107077A (en) | 1987-08-26 | 2000-08-22 | Yamamoto; Janet K. | Feline lymphoid cell lines capable of producing FIV for FIV diagnostics and vaccines |
AU640511B2 (en) * | 1990-07-30 | 1993-08-26 | Pharmacia & Upjohn Company | Hexa-n-(o-hydroxybenzyl) neomycin b for inhibiting human retroviruses and for the treatment of aids |
US5534408A (en) * | 1993-09-24 | 1996-07-09 | University Of Massachusetts Medical Center | 2-deoxystreptamine aminoglycoside inhibition of HIV RRE/Rev binding |
WO1994009792A1 (en) * | 1992-10-23 | 1994-05-11 | University Of Massachusetts Medical Center | Small molecule inhibition of rna/ligand binding |
ATE365049T1 (de) | 1994-05-10 | 2007-07-15 | Wyeth Corp | Abgeänderter, verbesserter brsv lebend- impfstoff |
IL163873A0 (en) | 1995-08-25 | 2005-12-18 | Univ Florida | Il-2 independent feline derived T cell |
-
2002
- 2002-05-03 ES ES02769679T patent/ES2369846T3/es not_active Expired - Lifetime
- 2002-05-03 AU AU2002342568A patent/AU2002342568B2/en not_active Expired
- 2002-05-03 YU YU88703A patent/YU88703A/sh unknown
- 2002-05-03 CZ CZ20033046A patent/CZ20033046A3/cs unknown
- 2002-05-03 PT PT02769679T patent/PT1385540E/pt unknown
- 2002-05-03 CN CNB028096002A patent/CN1326992C/zh not_active Expired - Lifetime
- 2002-05-03 DK DK02769679.8T patent/DK1385540T3/da active
- 2002-05-03 HU HU0400283A patent/HUP0400283A2/hu unknown
- 2002-05-03 CA CA2446131A patent/CA2446131C/en not_active Expired - Lifetime
- 2002-05-03 MX MXPA03010208A patent/MXPA03010208A/es active IP Right Grant
- 2002-05-03 WO PCT/US2002/014271 patent/WO2002091994A2/en active Search and Examination
- 2002-05-03 EP EP02769679A patent/EP1385540B1/en not_active Expired - Lifetime
- 2002-05-03 BR BRPI0209482-7A patent/BR0209482A/pt not_active IP Right Cessation
- 2002-05-03 EP EP10183838A patent/EP2298343A1/en not_active Withdrawn
- 2002-05-03 JP JP2002588913A patent/JP4283544B2/ja not_active Expired - Lifetime
- 2002-05-03 KR KR10-2003-7014613A patent/KR20040029981A/ko not_active Application Discontinuation
- 2002-05-03 AT AT02769679T patent/ATE521364T1/de active
- 2002-05-03 SI SI200230960T patent/SI1385540T1/sl unknown
- 2002-05-03 PL PL02373847A patent/PL373847A1/xx not_active Application Discontinuation
- 2002-05-03 NZ NZ529326A patent/NZ529326A/en not_active IP Right Cessation
- 2002-05-07 US US10/140,172 patent/US7160721B2/en not_active Expired - Lifetime
-
2003
- 2003-11-05 BG BG108315A patent/BG108315A/bg unknown
- 2003-11-07 NO NO20034961A patent/NO20034961L/no not_active Application Discontinuation
- 2003-11-24 HR HR20030974A patent/HRP20030974A2/hr not_active Application Discontinuation
- 2003-12-09 ZA ZA200309556A patent/ZA200309556B/xx unknown
-
2011
- 2011-09-23 CY CY20111100925T patent/CY1112123T1/el unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4215107A (en) * | 1978-12-29 | 1980-07-29 | Merck & Co., Inc. | Parainfluenza virus vaccine and its preparation |
Also Published As
Publication number | Publication date |
---|---|
CY1112123T1 (el) | 2015-11-04 |
PT1385540E (pt) | 2011-10-21 |
EP1385540A4 (en) | 2004-12-01 |
ATE521364T1 (de) | 2011-09-15 |
WO2002091994A2 (en) | 2002-11-21 |
MXPA03010208A (es) | 2004-03-10 |
DK1385540T3 (da) | 2011-10-24 |
KR20040029981A (ko) | 2004-04-08 |
JP2005508139A (ja) | 2005-03-31 |
NZ529326A (en) | 2006-09-29 |
CA2446131C (en) | 2013-07-02 |
HRP20030974A2 (en) | 2004-02-29 |
YU88703A (sh) | 2006-05-25 |
BR0209482A (pt) | 2007-01-02 |
WO2002091994A3 (en) | 2003-05-08 |
AU2002342568B2 (en) | 2007-11-01 |
CZ20033046A3 (en) | 2004-03-17 |
ES2369846T3 (es) | 2011-12-07 |
SI1385540T1 (sl) | 2011-10-28 |
CA2446131A1 (en) | 2002-11-21 |
ZA200309556B (en) | 2005-02-23 |
HUP0400283A2 (en) | 2007-08-28 |
NO20034961D0 (no) | 2003-11-07 |
NO20034961L (no) | 2003-12-01 |
EP2298343A1 (en) | 2011-03-23 |
PL373847A1 (en) | 2005-09-19 |
US7160721B2 (en) | 2007-01-09 |
CN1514734A (zh) | 2004-07-21 |
JP4283544B2 (ja) | 2009-06-24 |
EP1385540A2 (en) | 2004-02-04 |
US20020197714A1 (en) | 2002-12-26 |
EP1385540B1 (en) | 2011-08-24 |
BG108315A (bg) | 2005-03-31 |
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