CN1325018C - Cardiac muscle and skeletal muscles physiologically electrical signal data gathering and signal handling system - Google Patents
Cardiac muscle and skeletal muscles physiologically electrical signal data gathering and signal handling system Download PDFInfo
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- CN1325018C CN1325018C CNB2004100011591A CN200410001159A CN1325018C CN 1325018 C CN1325018 C CN 1325018C CN B2004100011591 A CNB2004100011591 A CN B2004100011591A CN 200410001159 A CN200410001159 A CN 200410001159A CN 1325018 C CN1325018 C CN 1325018C
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Abstract
The present invention relates to a cardiac muscle and skeletal muscle physiological electrical signal data gathering and signal handling system which is used for a preclinical medicine experiment and research. The present invention is characterized in that the system comprises an electric stimulator, a signal isolator, an averaging instrument, an oscillograph, a data gathering A/D transfer card and a microcomputer, wherein the oscillograph conveys output analogue quantity to the A/D transfer card after pre-amplifying an input electrical signal so that the output analogue quantity is gathered and handled by the computer; when an experiment waveform and data are gathered in real time by the hardware equipment of the computer and the data gathering A/D transfer card, the gathering, the record, the storage, the handling and the display of the waveform and the data are finished by system application software, and an analysis and inference result are given. The present invention has the advantage that the system has large reference value for medicine diagnosis, electrolyte influence and the like by an analysis result of a myoelectric electrical signal waveform. A skeletal muscle electrical signal has large reference value for the processing and the treatment of skeletal muscle injury.
Description
Technical field
The invention belongs to preclinical medicine and detect the automated information technical field, data acquisition of a kind of myocardium skeletal muscle electro-physiological signals and signal processing system particularly are provided, be used for preclinical medicine experiment and research.
Background technology
In the basic medical research process, research worker use preclinical medicine experimental apparatus is carried out real-time waveform detection and demonstration to cardiac muscle, the skeletal muscle electro-physiological signals of laboratory animal, but can not gather, store and handle these signals, therefore can't carry out real time record to experimental waveform, also can't carry out deep research and analysis waveform.
Now, the display recorder device on the market is a lot, as: nixie display, automatic-balance type recorder, pen gauche form monitor, oscillograph, tape recorder etc.Wherein, oscillographic frequency response range is the widest, is best suited for to carry out the signal observation.Yet the research that oscillograph can not be preserved data or figure after getting off to be provided with is used.Tape recorder is compared with other recording equipment very wide frequency response range and lower signal distortion, and the signal of record can be reset by oscillograph, but to signal can't accurately preserve, comparison and rapid analysis.In recent years Kuai Sufazhan computer technology provides instrument very easily for electrophysiologic study.At present, China has produced SMUP-PC type bio signal processing system and NSA-3 type medical signals processing system, but its price is very high, and can't with the supporting use of the existing complete experimental instrument and equipment of medical research unit.
Current, the Computer Applied Technology high speed development, utilizing computer that cardiac muscle, the skeletal muscle electro-physiological signals of laboratory animal are carried out real-time data acquisition, demonstration and storage, and data are analyzed and handled, is medical research inevitable development trend and basic medical research personnel's urgent needs.
Summary of the invention
The objective of the invention is to: a kind of system that is used for data acquisition of myocardium skeletal muscle electro-physiological signals and signal processing is provided, realizes real time record experimental waveform.
The present invention is made up of electrostimulator, signal isolator, averaging device, oscillograph, data acquisition A/D transition card, microcomputer.After wherein oscillograph carries out preposition amplification to input electrical signal, will export analog quantity and deliver to conversion A/D card, for computer acquisition and processing.When experimental waveform and data being gathered in real time by computer, data acquisition A/hardware devices such as D transition card, finish collection, record, storage, processing, demonstration by the system software of developing voluntarily, and provide and analyze and inferred results waveform and data.
The purpose of system software design is startup and the control that realizes the A/D transition card, collection is from the signal of telecommunication (carrying out preposition amplification through oscillograph earlier) of organism, the signal of telecommunication of gathering is shown synchronously, to the digital quantity after the conversion store, reproduction and computing.Native system is easy to operate, and signal graph shows accurately, can calculate the interval or the value of heart rate (electrocardiosignal) and each waveform.
System software will calculate the cycle time of each electrocardiosignal.The maximum characteristics of electrocardiosignal are that one precipitous " point " arranged in each cycle, and the interval between two " points " is exactly a cardiac electrical cycle.For these " points " of detecting from a series of signal, the time sum that occurs with a plurality of " point " can obtain an average cardiac electrical cycle divided by the number of " point ".See Fig. 6
Because the electrocardiosignal of various animals there are differences, so should be judged according to practical situation by the technical staff when analytical calculation, chooses calculating parameter.After selecting needed numerical value, program is calculated according to user-selected content and is shown.During specific implementation, earlier single cycle EGC pattern is presented on the certain window, allow the user to its convergent-divergent, move to the best image situation.When the user selected to begin to calculate, computer prompting input earlier sign so that describe the content of preparing the numerical value that calculates, was judged the relative distance of user with mouse selected and two positions clicking on figure then, to vertical coordinate, calculates the voltage height; To abscissa, calculate the time size.See Fig. 7
The invention has the advantages that: by the analysis to myocardium electro-physiological signals activity inventory, the rhythm and pace of moving things that can understand heart changes and the conduction situation, and diagnosis atrium, ventricle increase and myocardial infarction, ischemia, strain are had sure value.The analysis result of myocardial electrical signals waveform has bigger reference value to diagnostic medicine and electrolyte influence etc.The skeletal muscle signal of telecommunication has very big reference value to Skeletal muscle injury and processing, treatment.
The present invention is a data collection and signal processing system, and the application software of Yan Zhikaifaing can be realized following function in data acquisition and processing procedure voluntarily:
1. have the good man-machine interaction interface, make things convenient for the technical staff to use;
2. can show bioelectrical signals numerical value and curve in real time;
3. can store signal and data, can show, store and print graph curve;
4. the Based Intelligent Control expert system software by developing voluntarily can realize that signal analysis, waveform comparison and result infer.
Description of drawings
Fig. 1 is the hardware configuration sketch map of system of the present invention.
Fig. 2 is a systems soft ware framework sketch map of the present invention.Dotted portion is an addition Item.
Fig. 3 is real time system control figure of the present invention.Pick off: be a kind of non-electric physical quantity to be converted to the device of electric weight (voltage or electric current), just can convert temperature value to corresponding voltage signal as measuring temperature pick off thermocouple commonly used.The pick off that has is not directly to export electric weight, but converts non-electric physical quantity to corresponding resistance, changes in capacitance, as critesistor, can be used to measure temperature yet, uses as temperature sensor.
Amplifier: the input voltage range of A/D converter is a constant normally, and as 8 ADC0809 chip, its input voltage is 0-5V.Therefore and the amplitude of different signal of sensor has nothing in common with each other, and what have is very faint, needs carry out processing such as signal amplification through the signal processing link, makes to be added to input voltage on the A/D converter and defeated people's scope of A/D converter adapts.
Wave filter: be a kind ofly can allow a part of frequency signal pass through smoothly, and the signal of another part frequency is subjected to the electronic installation than high attenuation.For the signal that obtains from the scene, all be superimposed with various interfering signals usually, in order to prevent the influence of interfering signal, can use wave filter that interfering signal is filtered to the A/D transformation process.
Sampling hold circuit: in the A/D transformation process, because the input analogue signal is a continually varying, A/D finishes once to change then needs the regular hour, is exactly the conversion time of A/D during this period of time.Different principle realizes A/D converter required conversion time is different, and for fast-changing defeated people's signal, the time of A/D conversion just seems longer relatively, if do not take measures, then can cause bigger transformed error.For the precision that guarantees to change, must adopt sampling hold circuit, during sampling, the output of circuit is followed the variation of input voltage and is changed; During maintenance, the value the when output of circuit remains the sampling end is constant, up to entering sample states once more.Utilize sampling hold circuit just can guarantee to keep the big or small constant of the defeated people's signal of sampling in the A/D transition period, thus the transformed error of having avoided the variation because of input signal to cause.
Low-pass filtering: be used for filtering interfering and unnecessary signal.
Variable connector: be used for the output that timesharing connects each pick off, keep chip to use a sampling, A/D converter is sampled multi-analog timesharing ground and is changed.
A/D converter: analog quantity is converted to the digital quantity that calculates the function reception.
Microcomputer: the digital quantity that A/D is converted to carries out computing and processing.
D/A converter: digital quantity is become analog quantity.
Power amplifier: the driving force that is used for improving D/A output analog quantity.
Execution unit: be used for realizing control to the scene.
The interface signal that analog-digital converter is relevant with external equipment is the analogue signal of input.In the practical application circuit, this part circuit can add corresponding treatment circuit according to signal that peripheral hardware provided and A/D converter to the requirement of input signal.
Fig. 4 is a typical analog quantity input structure block diagram of the present invention.
Fig. 5 is a typical connection mode number converter sketch map of the present invention.The input of the analog-digital converter among the figure links to each other with external equipment, and output links to each other with CPU, and is connected to control corresponding line and condition line.
In order to realize data acquisition and input, corresponding analog signal processing circuit and input channel latch and correspondent control circuits must be arranged in the analog digital conversion interface.In order to realize the output of signal, also corresponding data output register must be arranged in the analog digital conversion interface, be convenient to the result that computer reads conversion.
Fig. 6 is a cardiac electrical cycle signal measured drawing of the present invention.
Fig. 7 is standard cardioelectric figure of the present invention and each several part name.
Fig. 8 is a data acquisition sketch map of the present invention.
Fig. 9 is a graphical data display window sketch map of the present invention.
Figure 10 is that Flame Image Process of the present invention shows sketch map.
Figure 11 is the calculating sketch map of numerical value of the present invention.
Claims (2)
1, data acquisition of a kind of myocardium skeletal muscle electro-physiological signals and signal processing system are made up of electrostimulator, signal isolator, averaging device, oscillograph, data acquisition A/D transition card, microcomputer; After wherein oscillograph carries out preposition amplification to input electrical signal, to export analog quantity and deliver to the A/D transition card, for computer acquisition and processing, when experimental waveform and data being gathered in real time by computer, data acquisition A/D transition card hardware device, finish collection, record, storage, processing, demonstration by system software, and provide and analyze and inferred results waveform and data; It is characterized in that: system software is realized startup and the control to the A/D transition card, gathers the signal of telecommunication from organism, the signal of telecommunication of gathering is shown synchronously, to the digital quantity after the conversion store, reproduction and computing; System software will calculate the cycle time of each electrocardiosignal, the maximum characteristics of electrocardiosignal are that one precipitous " point " arranged in each cycle, interval between two " points " is exactly a cardiac electrical cycle, for these " points " of from a series of signal, detecting, the time sum that occurs with a plurality of " point " can obtain an average cardiac electrical cycle divided by the number of " point "; When analytical calculation, should judge according to practical situation, choose calculating parameter by the technical staff, select needed numerical value after, program is calculated according to user-selected content and is shown.
2, according to the described system of claim 1, it is characterized in that: during specific implementation, earlier single cycle EGC pattern is presented on the certain window, allow the user to its convergent-divergent, move to the best image situation; When the user selected to begin to calculate, computer prompting input earlier sign so that describe the content of preparing the numerical value that calculates, was judged the relative distance of user with mouse selected and two positions clicking on figure then, to vertical coordinate, calculates the voltage height; To abscissa, calculate the time size.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100011591A CN1325018C (en) | 2004-02-02 | 2004-02-02 | Cardiac muscle and skeletal muscles physiologically electrical signal data gathering and signal handling system |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2004100011591A CN1325018C (en) | 2004-02-02 | 2004-02-02 | Cardiac muscle and skeletal muscles physiologically electrical signal data gathering and signal handling system |
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| Publication Number | Publication Date |
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| CN1557252A CN1557252A (en) | 2004-12-29 |
| CN1325018C true CN1325018C (en) | 2007-07-11 |
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| CNB2004100011591A Expired - Fee Related CN1325018C (en) | 2004-02-02 | 2004-02-02 | Cardiac muscle and skeletal muscles physiologically electrical signal data gathering and signal handling system |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1032287A (en) * | 1987-09-30 | 1989-04-12 | 中国人民解放军总医院 | Detect the apparatus and method of cardiac function by electricity irritation |
| US6360117B1 (en) * | 1999-05-24 | 2002-03-19 | Terry B. J. Kuo | Electrocardiogram signal collecting apparatus |
-
2004
- 2004-02-02 CN CNB2004100011591A patent/CN1325018C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1032287A (en) * | 1987-09-30 | 1989-04-12 | 中国人民解放军总医院 | Detect the apparatus and method of cardiac function by electricity irritation |
| US6360117B1 (en) * | 1999-05-24 | 2002-03-19 | Terry B. J. Kuo | Electrocardiogram signal collecting apparatus |
Non-Patent Citations (1)
| Title |
|---|
| 微机胜利多导记录处理仪的研制与应用 杨殿阁等，河北医学院学报，第16卷第3期 1995 * |
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