CN1325013C - Method for measuring general quality parameter of hairs - Google Patents

Method for measuring general quality parameter of hairs Download PDF

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CN1325013C
CN1325013C CNB991119711A CN99111971A CN1325013C CN 1325013 C CN1325013 C CN 1325013C CN B991119711 A CNB991119711 A CN B991119711A CN 99111971 A CN99111971 A CN 99111971A CN 1325013 C CN1325013 C CN 1325013C
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hair
stem
growth
optical recording
zone
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CN1267501A (en
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宋努·阿蒙西里巴尼猜
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1072Measuring physical dimensions, e.g. size of the entire body or parts thereof measuring distances on the body, e.g. measuring length, height or thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/448Hair evaluation, e.g. for hair disorder diagnosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N2021/8444Fibrous material

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Abstract

A method of measuring hair quality in a predefined area of the scalp. The method addresses the preparation of the scalp and the process for measuring the density, the size of hair shaft, the length of each hair growing out from the area. A video capture device capable of storing images transferred from a camera, computer hardware and software capable of archiving the images and measuring the size and length of each hair shaft in the images. A method of dying hair shafts combined with above image processing techniques will provide measure of almost every phases of hair cycle. The end result will be the statistical data of the ratio of growing hairs and non-growing hairs with the average of hair growth rates and other data such as the maximum and minimum growth rate, the standard error, the variance etc.

Description

The measuring method of general quality parameter of hairs
Technical field
The present invention relates to measure the method for multiple hair mass parameter, described parameter is for example for sending out diameter, the growth rate of each stem, the total time in each stage of growth cycle of hair of stem.Described method can be carried out repeatedly, and observing the dynamic change of these parameters, thereby this method can be used to study the variation of these hair parameters that cause owing to food, medicine, specific products, activity and custom.
Background technology
The problem of hair and disease, particularly chaeta, hair are sparse, all are very general in humans and animals.The thinning thin estimation of chaeta and hair may be because the many special variation of growth cycle of hair causes.If not the set out function of stem of executive chairman of the chaeta of very high percentage ratio and hair is arranged on the body part of being concerned about, then those chaetas and hair are in stopping of hair cycles or catagen phase.The hair that stops will to come off very soon, and in this stage, if shaving should the zone, then chaeta and hair are with no longer further growth.The stem that the hair follicle president who stays after a stem comes off makes new advances, a stem quantity of unit are will reduce if this process time is long, and cause at this place's formation white space.In another case, if new hair can grow immediately, but that new hair generate to be sent out the speed of stem is quite slow, and then new hair can not be complementary with normal hair on every side on length, thereby the hypotrichosis that seems.It is dense or sparse that the size of sending out stem determines that also hair looks like, because thicker to send out stem better to the little stem of reflection of light and absorptance diameter according to the color of hair.Each hair follicle produces simultaneously more than an ability of sending out stem will make that also the amount in certain zone is more.
Should measure in the growth stage of hair cycle about all parameters of sending out stem that bear.The stable growth rate of each stem is also extremely important along cunning, glossiness hair for acquisition.At last, come off and during stop phase before finishing the whole cycle, will determine the total duration of growth stage when hair stops growing and turns back to.Any persistent period that may force the dormant factor of root of hair all will shorten this growth stage, and increase automatically enters the number of the hair of above-mentioned stop phase.
Can measure sending out stem and not growing or carry out the percentage ratio of a stem of growth of growth if there is any method in common, so that calculate the approximate time that from empty hair follicle, grows new hair, and measure in all growths and send out the ratio of sending out stem that is bearing in the stem, calculate the sum of hair density in the given area, all send out the size and all changes of last these parameters of monitoring in the whole time-continuing process in growth period, withholding period and the stage of coming off of stem in observed unit area in measurement, and then the result of these data will make many people be benefited.The doctor can distinguish the problem of human hair more accurately according to the pathophysiology basis.The veterinary will know the quality of the fur that how to improve intact animal and infected animal.The food and medicine industry can adopt this method to study multiple possible food supplement, medical herbs goods and medicine may influence the hair of various certain quality in the whole cycle.Carefully multiple factor and effect clearly and different tasks are combined, can significantly strengthen the effect that makes fur, hair etc. healthy.This method also can be used to differentiate the humans and animals negative interaction of other food, product, medicine, activity and custom in daily life, and these information will help relevant industry improvement and improve the quality of its product, so that be of value to consumer.Government can utilize this method examination hair caring with hair care product and hair setting device, so that protection people's safety and interests.Yet, in fact, also do not have to have at present the method for described function.
At present the method that can obtain that adopts can calculate growing send out the percentage ratio of stem with respect to the part of not growing, but this method requires to shave off the hair of detected part and observed after several days.This method can not be used to not shave the zone of hair, and is not used to obtain any conclusion of persistent period of the growth cycle of hair of relevant necessity of mentioning as leading portion.In addition, can not measure and be recorded in any change of sending out diameter stem size and rate of growth in the growth course of same stem.
Though also can obtain the measuring method of hair density by the special arrangement that obtains the photo that is used for artificial counting or image, this method can not provide the information how hair density changes.
Exactly, the dynamic change of all parameters of hair in the whole life can not critically be observed and be recorded in to all obtainable methods all.
In addition, all obtainable methods do not have actual help to daily basic application, and the people who wants actual these methods of employing in medical department is benefited.
Summary of the invention
The present invention proposes a kind of hair method for quality that is used to measure, and this method may further comprise the steps:
A. identify a selected skin or an area of scalp, preferably the hair mass measurement need be carried out to this zone in a zone that comprises the calm labelling of a pigment;
B. one first optical recording is carried out in this zone, so that with its original state of file record;
C. bleach or dye the stem of sending out in the described selection area;
D. after step b and step c in succession,, described selection area is carried out a final optical recording through a predetermined waiting time;
E. handle the data that get from described first optical recording and final optical recording, so that determine the change of hair parameter.
Preferably, described hair parameter is the number of hairs of the hair density in described selection area, growth and not growth, the stem quantity sending out diameter stem and/or grow from scalp.
Preferably, after described step e, carry out following another step:
F. number go out and measure painted with uncoloured stem with send out point so that calculate hair growth.
Preferably, step a to e or step a to f repeat at least once by one month, two months, the interval of half a year or 1 year separately.
Preferably, be used to measure the hair mass parameter by the colored segment of described method generation and the alternately band of natural color segment.
Preferably, after the step c, described selection area is carried out one second optical recording, painted state fully for confirmation.
Preferably, after the step f, pick out the not hair of growth, so that set the time point that root of hair fluffs or soon comes off, and the date selected in record.
Preferably, described selection area identifies by the device that uses machinery and/or the described zone of electronic marker.
Preferably, described staining procedure uses fluorescent dye.
Preferably, a device that can mate an old image and an image that obtains recently automatically is used to store all optical recordings.
Preferably, the optical recording of described acquisition is stored and files, so that they can be retrieved, is used for further statistical computation.
Preferably, the result of described step a to f also is used to determine the influence to the hair quality of food, medicine, product, device, activity and the custom of any kind.
Preferably, the final optical recording at selection area described in the steps d carried out after 1 to 7 day.
The present application a kind of new method that is used for measuring in the required most parameters of the total quality of observed zone appraiser and animal hair.This new invention will provide following result:
1. the hair of not growing in measured zone is with respect to the accurate percentage ratio of the hair of growth.
2. roughly the interval of each hair follicle between the early stage mark picture of alopecia point and regeneration New Development stem apex end.
3. on any point of its whole life, produce the speed of single stem every day.
4. the diameter dimension of each stem relevant with the data in the 3rd.
5. entered and left the number of hairs of stop phase in every month.
6. single hair since first day up to the whole growth persistent period that surpasses till entering stop phase.
7. hair rests on the not total time of growth stage before coming off.
8. can obtain rudiment activity in each hair follicle more than the hair follicle of one stem.
9. in the 8th hair follicle of being mentioned, the dynamic change of each stem parameter.
All results all can be recorded and retrieve, so that further carry out statistical computation and comparison, thereby understand many in the effect for factor known and unknown aspect the health of hair and the quality of food, medicine, hair care product, activity and custom.
Description of drawings
Fig. 1 is illustrated in the little infringement (P) that identifies in the detection zone.
Fig. 2 illustrates single hair and compares over time with the real image of impact point.
Fig. 3 illustrates the hair with natural hair color that grows from the skin of being studied.
Fig. 4 illustrates color segment and the natural hair color band of the sending out stem that are colored and alternates.
The specific embodiment
The privileged sites that are used as the skin of object of study on long crinite body part preferentially select those that infringement of nature pigmentation, for example nevus, mole, lentigo, ketatosis seborrheica, telangiectatic zone are arranged.Each when we need check the variation of all hair mass parameters, can determine the position that these infringements are regional at an easy rate.As shown in Figure 1, the little infringement (P) that is easy to discern in detection zone also can help to demarcate the particular location of each hair follicle.This simple technology will provide good chance for the observer observes each stem that is determined in the time that hair is measured special variation.
Need not any preserved skin operation in advance, only with natural labelling as indicating accurately, can provide the information of hair density, hair dimension and the single hair of rough estimate to compare and whether grow over time, as shown in Figure 2 with the real image of impact point.Hair follicle 1 shows from improving the New Development point that stem bears of sending out of growth.Hair follicle 2 shows the previous disappearance of sending out stem.Hair follicle 3 shows the variation of sending out the diameter stem size.
Adopt this natural labelling as simple and attempt effectively labelling is not noted as yet and introduce practice for above-mentioned advantage.Yet, do not have under any native labelled situation, and though be scalp overlook photo or lateral photo all is used as layout, to identify detected approximate location.Because the many more accuracies that obtain in the step that adopts elementary statistics calculating to analyze of data are high more, select several regions to detect.
Method of the present invention also comprises a simple coloring hairs step.Employing is easy to the varicolored cream rinse and the bleaching liquid that find in the supermarket, use on a small quantity in the per unit measured zone, and for example consumption is 0.3ml.Selected stain with particular color (brown, blueness, green, redness etc.) (as the back will be described in detail, definite time will by calibration in advance) after applying about 1 hour makes and sends out stem by permanent stain.Clean or clean simply this zone with shampoo then.Observe the zone that is colored by electronic image pickup device with enough amplifications.Last step is all stems to be carried out the decolouring (according to different stain brands and color the precise time of decolouring step being calibrated is useful equally) of success at the point that a stem grows from skin.
Behind the twenty four hours to one 168 hours (1-7 days), under video camera, observe the same area, and image is caught in person's observation according to the observation.Adjust the angle of video camera, when all hairs around the labelling on the new images have the similar orientation of orientation on the previous image with storage when detecting for the first time till.
In Fig. 3 of expression new images, the hair that has some from the skin of being studied, to grow with natural hair color, shown at hair follicle label 1,2,3, they have different length.Many hairs also have the color of catching as the stain of seeing by selecting for use (hair follicle label 4 and 5) when the dyeing stage finishes.Can write down the percentage ratio of growth hair and the hair of not growing from these data, in order to do further comparison.
In order to calculate the growth rate of each stem, must measure the length of each stem singly with normal color development.According to the record video camera amplification and finish the time point of staining procedure and, these data carried out mathematical calculation being colored the total amount of the interval between the time point of measuring once more in the zone.This can manually or automatically be carried out by preprepared tabulation or the mathematical routine that comprises the result of known formula, and wherein said formula can be found actual rate of growth.The tested length that this productivity ratio equals to obtain from image (millimeter or inch) is divided by magnification factor and time slot (by the hour or day record).The data that obtain are introduced maximum, minima, mode, the intermediate value of the whole region growing rate within standard deviation that can draw in the actual normal statistics calculating.This value and different time are compared from other value that the same area obtains, or compare, so that draw the conclusion whether the hair growth rate has significant change with the value that obtains from zones of different.
The persistent period of the dynamic change of following the tracks of each hair of not growing between the day that it comes off when being given in stop phase and beginning and they come off.This time interim, adopt artificial technology or device gently to spur these hairs, at length write down the time point that root of hair gets loose and prepares to drop.Become emptyly in case there has not been hair in the hair follicle, continue to follow the tracks of this point, so that observe when just beginning to grow hair follicle at the tip of new hair.The interval that the tip-growth of observation hair is come out goes on record and is used for representing the total time of hair cycle in this stage.
In this stage, as described below, the present invention has another advantage.After detecting with the data of collecting the hair percentage ratio of not growing, by checking the minimizing quantity at previous painted the stem in the junction of sending out stem and skin, the observer can observe the progress that this percentage ratio changes weekly.The minimizing number of the dyed hair of mentioning in last should equal the quantity of detected regional alopecia.Yet the dyed hair that stays is not represented the sum that stops hair in this zone, because on any time in this observation step, some among the stem that is unstained may stop growing.This observation has only provided had also retaining or come off before newly detecting for how many hairs that stop in last time observing.This information will help explanation to test from new dyeing to obtain how many hairs of not growing and enter the result of the fact of stop phase recently.
Observe by carrying out this class, can quite accurately measure the dynamic change that hair entered and left stop phase.The hair total amount that enters stop phase in a specific time range is extremely important for further analysis.So can illustrate in greater detail the independent percentage ratio of the hair of not growing in this zone of monitoring on the time point in office by the step that adopts this method.This technical step can provide following result:
1. enter and leave the dynamic change of the hair of stop phase.
2. if increase for the number of hairs that is in stop phase, whether the number of hairs that then enters stop phase more, or leave stop phase hair quantity whether still less, provide correct answer.
3. provide as in the quantity of the hair that leaves or come off as shown in the x axle with as the holography demonstration of the frequency of the hair that comes off in this zone as shown in the y axle.
Can not obtain total benefit in the past, and can realize this simple invention at these benefits without any prior art according to this simple staining technique of the present invention.The present invention can find that not only approximate time and the empty hair follicle from the halt of hair growth to the hair cycle of separation point grows the required time of New Development point, also have measurement and begun to the function of total growth time of its day that stops growing by the date that grows the hair follicle under its skin from the New Development point, this stage is another important stage in whole cycle of each hair.
Select varicolored hair dye, the order of record color and the definite date that is intended for use in this step of the present invention.To send out stem dyeing as in the previous paragraph, in these hair follicles, some new hairs that just entering growth stage will grow the tip from the New Development hair follicle that forms again.Described color will be dyed on the stem of old hair and on the point of new hair.When a point is colored, dyes in the color of sending out on the point and will inform the observer.The shades of colour that is adopted will have its oneself dat recorder.Therefore, according to based on the regulation from the width of the stem section measuring for the first time the situation of the rate of growth that obtains and be colored at every turn, every month, per two months, per season or every half a year dye to same zone.
But each dyeing must be adopted as the color sequences of the plan of entire method preparation, and each stain should be separated enough distances by the natural hair color of a stem at least.Along with effectively carrying out of step, in Fig. 4, the color segment of sending out stem that is colored will alternate with the natural hair color band significantly.By the similar step of dual-staining and wait periodically according to plan, any hair that comes off will have the artificial color zebra shape striped alternate with natural color on the whole length of hair.Artificial color will be according to plan seriatim (I, II, III, IV, V and VI) be arranged in the gamut of hair.Collect all hairs that point is colored, from putting 1 to putting 2, putting 2 to putting 3, putting 3 to each natural color segment of ground, root of hair end measurement.No matter how many sections are arranged on each hair sample, this measurement all will be from first section end that lasts till root of hair always.Hair A has the color that six sections quilts dye to be had from color I to color VI, and hair B has only three sections to dye the color that has from color III to color VI.To provide the persistent period that its growth is spent by the point 1 of the rate of growth timing of this section and the distance of putting between 2.Simply all are calculated the date addition that obtains from each section and will roughly provide total growth persistent period of particular hair.
In a diverse ways, painted hair stops growing in case send out sharp, then cuts off this hair and is used for similar measurement, to provide the clearer and more definite time of the growth stage that does not comprise the total time that stops.Nature, in the same area, the asynchronism(-nization) that each new hair grows.Yet, have the hair of equally sending out color sharp and be assumed to be at one time and grow.Each hair group that representative grows out from the same area different time on the color theory at each hair tip.Further relatively whether the persistent period of each hair group growth will be for having the improvement of any hair quality relevant with the total duration of growth to provide valuable opinion.
The present invention who produces unique hair specimen of the described total duration that is used for measuring growth will help to state clearly the information that obtains from second section step formerly of mentioning.Never the someone proposed similar techniques, to be provided at the possibility of research hair quality under this yardstick.
In order to catch the image that all are mentioned, electronic image pickup apparatus is used to obtain static electronic image as A71-50N Scalar ccd scanner (Tokyo yoyogi shibuya-ku 3-28-6 Scalar company).The asymmetric digital video of passing through 5.0 editions then generates catcher (AsymetrixDigital Video Producer Capture, (WWWW.asymetrix.com) or Aver (AverMedia Technologies Inc) converts this still image to Microsoft's Window bitmap mapping program (Microsoft window bitmap paint program).Window 3.11 and window95 all can be used to memory image.Then, this image can be preserved and extract again by filing, in order to data are studied.Statistical analysis program, for example SPSS program (SPSS.co) is used to calculate.

Claims (9)

1. be used to measure the hair method for quality, this method may further comprise the steps:
A. identify a selected skin or an area of scalp, preferably the hair mass measurement need be carried out to this zone in a zone that comprises the calm labelling of a pigment;
B. one first optical recording is carried out in this zone, so that with its original state of file record;
C. bleach or dye the stem of sending out in the described selection area;
D. after step b and step c in succession,, described selection area is carried out a final optical recording through a predetermined waiting time;
E. handle the data that get from described first optical recording and final optical recording, so that determine the change of hair parameter.
2. method according to claim 1 is characterized in that, described hair parameter is the number of hairs of the hair density in described selection area, growth and not growth, the stem quantity sending out diameter stem and/or grow from scalp.
3. method according to claim 1 is characterized in that, after described step e, carries out following another step:
F. number go out and measure painted with uncoloured stem with send out point so that calculate hair growth.
4. method according to claim 3 is characterized in that, is used to measure the hair mass parameter by the colored segment of described method generation and the alternately band of natural color segment.
5. method according to claim 1 is characterized in that, after the step c, described selection area is carried out one second optical recording, painted state fully for confirmation.
6. method according to claim 3 is characterized in that, after the step f, picks out the not hair of growth, so that set the time point that root of hair fluffs or soon comes off, and the date selected in record.
7. method according to claim 1 is characterized in that the optical recording of described acquisition is stored and files, so that they can be retrieved, is used for further statistical computation.
8. method according to claim 3 is characterized in that, the result of described step a to f also is used to determine the influence to the hair quality of food, medicine, product, device, activity and the custom of any kind.
9. method according to claim 1 is characterized in that, carries out after 1 to 7 day at the final optical recording of selection area described in the steps d.
CNB991119711A 1999-03-22 1999-08-05 Method for measuring general quality parameter of hairs Expired - Fee Related CN1325013C (en)

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AU (1) AU767902B2 (en)
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CN1267501A (en) 2000-09-27
AU767902B2 (en) 2003-11-27
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TW422688B (en) 2001-02-21
US6389150B1 (en) 2002-05-14
AU4748299A (en) 2000-10-05

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