CN1319496C - Transfusion apparatus for animal capable of ratating in 360 deg - Google Patents

Transfusion apparatus for animal capable of ratating in 360 deg Download PDF

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Publication number
CN1319496C
CN1319496C CNB2004100845610A CN200410084561A CN1319496C CN 1319496 C CN1319496 C CN 1319496C CN B2004100845610 A CNB2004100845610 A CN B2004100845610A CN 200410084561 A CN200410084561 A CN 200410084561A CN 1319496 C CN1319496 C CN 1319496C
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China
Prior art keywords
transfusion
tube
central shaft
animal
rotatable
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Expired - Fee Related
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CNB2004100845610A
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Chinese (zh)
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CN1608600A (en
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秦环龙
丁在咸
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Shanghai Jiaotong University
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Shanghai Jiaotong University
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Abstract

The present invention relates to a 360-degree rotatable animal liquid transfusion device. A coaxial linked structure is formed from a multipurpose rotary bracket, a rotatable center shaft with a hole, and a flexible stainless steel transfusion tube, wherein the rotary bracket is connected with the rotatable center shaft with a hole, and the center shaft is fixed in a ball bearing seat. The fixing flat plate of the bearing seat is connected with the fixing flat plate of the transfusion device through bolts; the fixing flat plate of the transfusion device is fixed on an experimental animal cage. A transfusion silicon rubber tube penetrates through the inner hole of the rotatable center shaft with a hole and the flexible stainless steel transfusion tube to be connected with tube cavities of the tested animal's vein tube/digestion tube, etc. The transfusion device can easily and automatically move in the experimental cage in any direction along the tested animal under the action of the oily sealed ball bearing; the transmission of liquid is free from any influence. The present invention can study the animal medicine metabolism of small experimental animals under the dynamic conditions; the obtained relevant data is true and accurate and conforms to natural science rules.

Description

The rotatable liquids of animals infusion device of 360 degree
Technical field
The present invention relates to the rotatable liquids of animals infusion device of a kind of 360 degree, be used in laboratory environment, carrying out the scientific experiments of aspects such as biological nutrition, clinical pharmacy, belong to medical science and medical scientific research animal experiment technique at the experiment meiofauna.
Background technology
In a large amount of life medical researchs, medicine research and development and production process, laboratory animal is crucial subjects.But how to simulate the animal nature living environment under different experimental conditions; make tested animal under arm's length basis metabolism condition, be engaged in related science research; meet the laboratory animal welfare simultaneously; follow laboratory animal ethics; and the experimental data that provides true, accurate for this reason, meets scientific law, be the common hopes of pursuing of numerous researchers.Laboratory animal is in the experiment condition and lab space of regulation, by it being provided metastable feed, drinking-water, rest, drainage activity space, simulated animal nature life habit as far as possible, Animal nutrition absorbs to obtain meeting, the experimental data of pathology evolution process under the normal physiological processes of energy metabolism or the disease conditions.
Traditional animal infusion set generally all is that infusion set and acceptor are non-coaxial two parts, can not link simultaneously.And existing animal experiment method carries out the liquid infusion experiment of the outer nutrition of relevant enteral and other biological metabolism aspect normally under the condition to tested animal row general anesthesia or pressure Baoding, and therefore the deficiency of following several respects is arranged:
(1) under static conditions, tested animal is because of being anaesthetized or being whipped, and its basal metabolic rate descends, and the energy metabolism activity reduces, so that organism physiology, biochemical many relevant parameters change, and are difficult to tested animal life activity and the active real conditions of nutrient metabolism under the simulating natural condition.
(2) the liquid infusion device owing to can not do the circumference rotation, will inevitably make the connection flexible pipe be distorted, roll over flat distortion because of the activity of animal subject, so that liquid can not normally be input in the body of animal subject as being other soft methods of attachment of non-coaxial rotation.
(3) being suitable for relevant experimentation is limited in scope.
(4) be forced to Baoding as animal subject, must cause the abnormal change of this animal aspect spirit and behavior, even cause the body wound of the non-empirical factor of animal subject, also do not meet the ethical spirit of love laboratory animal and kind treatment laboratory animal.
Summary of the invention
The objective of the invention is at the deficiencies in the prior art, provide a kind of 360 degree rotatable liquids of animals infusion device, can carry out the liquid infusion experiment of vein or other histoorgan and not be subjected to the influence of arbitrary motion laboratory animal, for laboratory animal provides one can keep the autonomic activities ability, the laboratory environment of free relatively activity space is arranged.
For realizing such purpose, in the rotatable liquids of animals infusion device of 360 degree of the present invention's design, form coaxial linkage structure by multiduty runing rest, rotatable central shaft with holes and flexible rustless steel tube for transfusion, runing rest is with the central shaft disjunctor rotatable with holes that is fixed in the ball-bearing housing, the bearing block fixed flat planar is connected by bolt with the infusion device fixed flat planar, and the infusion device fixed flat planar is fixed on the laboratory animal cage tool.The transfusion silica gel tube passes the endoporus and the flexible rustless steel tube for transfusion of rotatable central shaft with holes, links to each other with tube chamber such as animal subject vein/digestive tube.Under the effect that contains the oil seal ball bearing, infusion device can be portable be made the autonomic movement of any direction with animal subject in experimental cage, and liquid is carried and is not affected.
Concrete structure of the present invention is formed and is comprised runing rest, rotatable central shaft with holes, contains the oil seal ball bearing, bearing block fixed flat planar, infusion device fixed flat planar and flexible rustless steel tube for transfusion.Runing rest serves many purposes, can be used for being connected with the liquid storage container or the transfusion instrument platform of apolegamy, runing rest is with rotatable central shaft disjunctor with holes, rotatable central shaft with holes passes cover in the ball bearing, and be fixed in the ball-bearing housing by the ball bearing overcoat, ball-bearing housing and bearing block fixed flat planar disjunctor, the bearing block fixed flat planar is connected by set bolt with the infusion device fixed flat planar, and the infusion device fixed flat planar is fixed on the corresponding laboratory animal cage tool by set bolt.Flexible rustless steel tube for transfusion is fixed on the bottom of rotatable central shaft with holes by tube for transfusion central shaft anchor tip, and communicate with the central shaft endoporus of rotatable central shaft with holes, the other end of flexible rustless steel tube for transfusion is fixed on one's body the animal subject by tube for transfusion animal end anchor tip and tube for transfusion animal end stator.
The liquid storage container of built-in test medicine or nutrient liquid is put in people's runing rest, and the transfusion silica gel tube passes the endoporus and the flexible rustless steel tube for transfusion of rotatable central shaft with holes, links to each other with tube chamber such as animal subject vein/digestive tube, and liquid is imported in the animal body.
Among the present invention; runing rest, rotatable central shaft with holes and flexible rustless steel tube for transfusion form coaxial linkage structure; flexible rustless steel tube for transfusion is imbued with rigidity and crooked flexible; certain extensibility is arranged; under the effect that contains the oil seal ball bearing; can be very portable in experimental cage, make the autonomic movement of any direction, and liquid is carried and is not affected, have rigidity and flexible rustless steel tube for transfusion more can be protected built-in transfusion silica gel tube with animal subject.
Runing rest among the present invention has many clocks purposes, can place liquid storage container, also can be connected with the transfusion instrument platform.Liquid storage container or transfusion instrument platform, multipurpose runing rest, central shaft tube for transfusion endoporus can hold 1~3 road infusion pipeline according to the experiment needs to be passed through.
The present invention is applicable to the small test animal to be the scientific research of the aspects such as clinical medicine, clinical pharmacy and biological nutrition medical science of object, also be applicable to the clinical and scientific research of aspects such as veterinary, Animal diseases diagnosis and treatment, wherein test the animals such as cat, rabbit, Cavia porcellus, avian species and rat that meiofauna comprises body weight≤3KG.
The present invention is novel, simple in structure and cost is cheap, infusion vessel or transfusion instrument platform total load head in apolegamy are under the situation of 2.5KG, tested laboratory animal can be made the voluntary movement of plane or vertical or circumferencial direction in transfusion cage tool, each class I liquid I that experiment is failed all can be imported in the animal subject body under the situation of no boosting or Micropump boosting safely, accurately.The present invention can continue under the dynamic condition, by connection to organs such as blood vessel, digestive tubes, experimental liquid is infused in the tested animal body, more true and meet the experimental data of natural physiology of animal and biological metabolism rule with the experiment infusion set that obtains more non-coaxial rotation.Patent device has obviously been improved the tested animal survival condition under the experiment condition, meets Laboratory Animal Facility and requires and the animal ethical spirit.Use apparatus of the present invention, can carry out the scientific research of aspects such as laboratory animal biological nutrition, clinical medicine, clinical pharmacy and bio-energy metabolism widely.
Description of drawings
Fig. 1 is the vertical view of stereochemical structure of the present invention.
Among Fig. 1,2. runing rest, 3. rotatable central shaft with holes, 4. central shaft endoporus, 9. bearing block fixed flat planar, 10. dull and stereotyped bolt hole, 11. infusion device fixed flat planars, 12. fixed bolt holes, 13. flexible rustless steel tube for transfusion, 14. tube for transfusion central shaft anchor tip, 15. tube for transfusion animals end anchor tip, 16. tube for transfusion animals end stator.
Fig. 2 is the upward view of stereochemical structure of the present invention.
Among Fig. 2,2. runing rest, 3. rotatable central shaft with holes, 4. central shaft endoporus, 6. overlap in the ball bearing, 10. dull and stereotyped bolt hole, 11. infusion device fixed flat planars, 12. fixed bolt holes, 13. flexible rustless steel tube for transfusion, 14. tube for transfusion central shaft anchor tip, 15. tube for transfusion animals end anchor tip, 16. tube for transfusion animals end stator.
Fig. 3 is a planar structure sketch map of the present invention.
Among Fig. 3,2. runing rest, 3. rotatable central shaft with holes, 4. central shaft endoporus, 5. ball bearing, 6. overlap in the ball bearing, 7. ball bearing overcoat, 8. ball-bearing housing, 9. bearing block fixed flat planar, 11. the infusion device fixed flat planar, 13. flexible rustless steel tube for transfusions, 14. tube for transfusion central shaft anchor tips.
The specific embodiment
Below in conjunction with accompanying drawing technical scheme of the present invention is further described.
Plan structure of the present invention mainly comprises runing rest 2, rotatable central shaft 3 with holes, bearing block fixed flat planar 9, infusion device fixed flat planar 11 and flexible rustless steel tube for transfusion 13 as shown in Figure 1.Multiduty runing rest 2 is used for being connected with the liquid storage container or the transfusion instrument platform of apolegamy, and runing rest 2 is with rotatable central shaft 3 disjunctors with holes, and rotatable central shaft 3 with holes is fixed in the ball-bearing housing with bearing block fixed flat planar 9 disjunctors.Flexible rustless steel tube for transfusion 13 is fixed on the bottom of rotatable central shaft with holes 3 by tube for transfusion central shaft anchor tip 14, and communicate with the central shaft endoporus 4 of rotatable central shaft 3 with holes, the other end of flexible rustless steel tube for transfusion 13 is fixed on one's body the animal subject by tube for transfusion animal end anchor tip 15 and tube for transfusion animal end stator 16.All have dull and stereotyped bolt hole 10 on bearing block fixed flat planar 9 and the infusion device fixed flat planar 11, bearing block fixed flat planar 9 overlays on the infusion device fixed flat planar 11, links to each other with infusion device fixed flat planar 11 by dull and stereotyped bolt hole 10 and set bolt.Also have fixed bolt hole 12 on the infusion device fixed flat planar 11, infusion device is fixed on corresponding laboratory animal (raising) the metabolic cage tool by fixed bolt hole 12 and set bolt.
Fig. 2 is the upward view of stereochemical structure of the present invention.As shown in Figure 2, runing rest 2 is with rotatable central shaft 3 disjunctors with holes, and rotatable central shaft 3 with holes passes the interior cover 6 of ball bearing and is fixed in the ball-bearing housing.Flexible rustless steel tube for transfusion 13 is fixed on the bottom of rotatable central shaft with holes 3 by tube for transfusion central shaft anchor tip 14, and communicate with the central shaft endoporus 4 of rotatable central shaft 3 with holes, the other end of flexible rustless steel tube for transfusion 13 is fixed on one's body the animal subject by tube for transfusion animal end anchor tip 15 and tube for transfusion animal end stator 16.All have dull and stereotyped bolt hole 10 on bearing block fixed flat planar 9 and the infusion device fixed flat planar 11, infusion device fixed flat planar 11 links to each other with bearing block fixed flat planar 9 by dull and stereotyped bolt hole 10 and set bolt, also has fixed bolt hole 12 on the infusion device fixed flat planar 11.
Fig. 3 is a planar structure sketch map of the present invention.
Among Fig. 3, as shown in Figure 3, runing rest 2 is with rotatable central shaft 3 disjunctors with holes, rotatable central shaft with holes 3 passes cover 6 in the ball bearing, and be fixed on 8 li of ball-bearing housings by ball bearing overcoat 7, contain oil seal ball bearing 5 in ball bearing, overlap 6 and ball bearing overcoat 7 between, ball-bearing housing 8 and bearing block fixed flat planar 9 disjunctors.Bearing block fixed flat planar 9 overlays on the infusion device fixed flat planar 11, and links to each other with infusion device fixed flat planar 11 by set bolt.Flexible rustless steel tube for transfusion 13 is fixed on the bottom of rotatable central shaft with holes 3 by tube for transfusion central shaft anchor tip 14, and communicate with the central shaft endoporus 4 of rotatable central shaft 3 with holes, the other end of flexible rustless steel tube for transfusion 13 will be fixed on one's body the animal subject.
Runing rest 2 among the present invention serves many purposes, and can place liquid storage container, also can be connected with the transfusion instrument platform.Liquid storage container or transfusion instrument platform, multipurpose runing rest, central shaft tube for transfusion endoporus can hold 1~3 road infusion pipeline according to the experiment needs to be passed through.
Among the present invention; runing rest 2, rotatable central shaft 3 with holes and flexible rustless steel tube for transfusion 13 form coaxial linkage structure; flexible rustless steel tube for transfusion 13 is imbued with rigidity and crooked flexible; certain extensibility is arranged; under the effect that contains oil seal ball bearing 5; can be very portable in experimental cage, make the autonomic movement of any direction, and liquid is carried and is not affected, have rigidity and flexible rustless steel tube for transfusion 13 more can be protected built-in transfusion silica gel tube with animal subject.

Claims (3)

1, the rotatable liquids of animals infusion device of a kind of 360 degree, it is characterized in that by runing rest (2), rotatable central shaft with holes (3) and flexible rustless steel tube for transfusion (13) form coaxial linkage structure, runing rest (2) is with rotatable central shaft with holes (3) disjunctor, rotatable central shaft with holes (3) passes cover (6) in the ball bearing, and be fixed on ball-bearing housing (8) lining by ball bearing overcoat (7), ball-bearing housing (8) and bearing block fixed flat planar (9) disjunctor, bearing block fixed flat planar (9) links to each other with infusion device fixed flat planar (11) by set bolt, have fixed bolt hole (12) on the infusion device fixed flat planar (11) and be fixed on the laboratory animal metabolic cage tool by set bolt, flexible rustless steel tube for transfusion (13) is fixed on the bottom of rotatable central shaft with holes (3) by tube for transfusion central shaft anchor tip (14), and communicate with the central shaft endoporus (4) of rotatable central shaft with holes (3), the other end of flexible rustless steel tube for transfusion (13) has tube for transfusion animal end anchor tip (15) and tube for transfusion animal to hold stator (16).
2, according to the rotatable liquids of animals infusion device of 360 degree of claim 1, it is characterized in that described runing rest (2) can place liquid storage container, also can be connected with the transfusion instrument platform.
3, according to the rotatable liquids of animals infusion device of 360 degree of claim 1, it is characterized in that described runing rest (2), central shaft endoporus (4) can hold 1~3 road infusion pipeline and pass through.
CNB2004100845610A 2004-11-25 2004-11-25 Transfusion apparatus for animal capable of ratating in 360 deg Expired - Fee Related CN1319496C (en)

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CNB2004100845610A CN1319496C (en) 2004-11-25 2004-11-25 Transfusion apparatus for animal capable of ratating in 360 deg

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CN1319496C true CN1319496C (en) 2007-06-06

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CN109044560B (en) * 2018-08-18 2020-12-29 安阳工学院 Animal doctor uses drencher

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900313A (en) * 1987-07-06 1990-02-13 Trustees Of The University Of Pennsylvania Mobile swivel and tether device for attachment to laboratory animals
US5816256A (en) * 1997-04-17 1998-10-06 Bioanalytical Systems, Inc. Movement--responsive system for conducting tests on freely-moving animals
CN2428110Y (en) * 1999-12-24 2001-05-02 上海医科大学附属华山医院 Rotary infusion device
CN2462882Y (en) * 2001-01-17 2001-12-05 屠伟峰 Continuous transfusion system
CN1142748C (en) * 1994-06-24 2004-03-24 株式会社津村 Adaptor for connector tubes to animal

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900313A (en) * 1987-07-06 1990-02-13 Trustees Of The University Of Pennsylvania Mobile swivel and tether device for attachment to laboratory animals
CN1142748C (en) * 1994-06-24 2004-03-24 株式会社津村 Adaptor for connector tubes to animal
US5816256A (en) * 1997-04-17 1998-10-06 Bioanalytical Systems, Inc. Movement--responsive system for conducting tests on freely-moving animals
CN2428110Y (en) * 1999-12-24 2001-05-02 上海医科大学附属华山医院 Rotary infusion device
CN2462882Y (en) * 2001-01-17 2001-12-05 屠伟峰 Continuous transfusion system

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