CN1307937C - Signal top searcher and searching method and application in blood pressure measurement - Google Patents
Signal top searcher and searching method and application in blood pressure measurement Download PDFInfo
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- 238000009530 blood pressure measurement Methods 0.000 title claims abstract description 24
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- 238000012360 testing method Methods 0.000 claims description 17
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Abstract
The present invention discloses a device for hunting the top end points of signals. The present invention comprises multiple operational amplifiers, multiple capacitors, resistors, variable resistors, diodes and transistors. The present invention can be used for measuring the top end points of ECG signals or PPG signals which are sent out by a human body, and the top end points can be used for measuring the blood pressure of the human body. Besides, the present invention also discloses a method for hunting the top end points of signals and the application of the method in blood pressure measurement thereof. The device of the present invention can be applied but not limited to a lossless type sphygmomanometer, a continuous sphygmomanometer and a non-wristlet air bag type sphygmomanometer, and the device aims to simplify late signal processing, such as the hunting procedures of the top end points of the signals. Therefore, some signal processors having relatively low calculation speed can be selected for signal analysis. Compared with the common signal processors, the present invention has low price and saves electricity; besides, because the procedures are simplified, the time for developing the processors is relatively reduced, and the cost benefits are greatly increased.
Description
Technical field
The present invention relates generally to signal measurement technique, particularly a kind of in blood pressure measurement, be used for searching human body provides such as the apparatus and method of the top point of the signal of ECG signal (ECG) or light change in volume trace signal (PPG) with and in the application of blood pressure measurement.
Background technology
Sphygomanometer now can be divided into damaged formula sphygomanometer and no damaged formula sphygomanometer two big classes.Because damaged formula sphygomanometer needs damaged patient's skin during measuring, cause bacterial infection and The blood streamed down easily.Therefore, for safety, the comfortable cause easily that reaches, general medical personnel and citizen are ready to adopt no damaged formula sphygomanometer to make the instrument of blood pressure measurement.
The damaged formula sphygomanometer of nothing now mainly comprises tone mensuration sphygomanometer (Tonometer), pulse sphygomanometer (Sphygmomanometer) and light change in volume sphygomanometer (Photoplethysmographic meter).
Tone is measured sphygomanometer and is utilized one group of pressure inductor to measure patient's blood pressure signal waveform, but because the price of the induction apparatus that is adopted in this method is higher and be subjected to the interference of measuring position easily, so unpopular on market.
The measuring method of pulse sphygomanometer has two kinds, is respectively auscultation (Auscultatory method) and vibratory drilling method (Oscillometric method).The auscultation ratio juris is to collect what is meant by Ke Shi sound (Korotkoff sounds).The vibration rule needs the help of wrist strap air bag to collect the pressure vibration signal.Its deficiency is in reusing the blood vessel pressurized that the pulse sphygomanometer can make the patient, and its accuracy is reduced, and is unfavorable for the continuous blood pressure measurement.
Light change in volume sphygomanometer mainly is divided into two kinds, and first kind of light change in volume sphygomanometer determined the variation of vessel inner blood volume by the variation of light, and finds out relative blood pressure thus.It is similar that this method supposition blood volume changes with blood pressure, but this hypothesis experimental results show that without strictness.Second kind of light change in volume sphygomanometer then utilized the relation between blood pressure and the pulse wave velocity (Pulsewave velocity).When increased blood pressure,, thereby pulse wave velocity is risen because the expansion of blood vessel causes the blood vessel hardening.Therefore, as long as find relation between pulse wave velocity and the blood pressure, just can measure patient's blood pressure.
Pulse wave velocity can be determined by pulse delivery time (Pulse Transit Time).The pulse delivery time then can be determined by the time difference of measuring ECG signal and light change in volume trace signal.Carry out the pulse delivery time when measuring in the time difference of utilizing ECG signal and light change in volume trace signal, common way is, the top point that adopts the top point of the R type ripple signal in the ECG signal and light change in volume trace signal is with respectively as the measurement basic point, and calculate the time difference between these two basic points, thereby determine the pulse delivery time.
There have been some instruments can utilize said method to carry out the measurement of pulse delivery time in the prior art.But, the shortcoming of these existing gauges is, it is used for carrying out the work that signal top point searches and is generally finished by the complex software program such as top point searching procedure, and the complex software program has higher requirement to signal processor, increased the development cost of whole instrument thus, and its development time is also longer.
Summary of the invention
Therefore, the present invention produces at above-mentioned shortcoming of the prior art, its objective is provides a kind of signal top point search device and method and the application in blood pressure measurement thereof, it can either make the signal top point search process in the blood pressure measurement process obtain simplifying, can also guarantee simultaneously to measure effectively the correct time that occurs as the signal top point of measuring basic point, and then utilize the lead time of measuring between the basic point as the reference index of measuring blood pressure.
To achieve these goals, described according to a first aspect of the invention, it provides a kind of signal top point search device, and this device comprises: input is used to import measured signal; The electric current steering detection circuit is used for exporting corresponding signal according to the input current direction of measured signal; Point testing circuit in top is used to detect the top point of measured signal, the amplitude of its output signal is maintained near the point of top as far as possible, and make its output signal be close to the direct current signal of certain amplitude; Amplitude regulating circuit, the amplitude that is used to regulate its input signal; The amplitude comparison circuit is used for the amplitude of its input signal is compared, and exports corresponding signal according to comparative result; On-off circuit is used for making under the control of control signal its signal that passes through to be switched on or to cut off; And outfan, be used for exporting signal to outside,
Wherein, measured signal is by described input, described top point testing circuit and described amplitude regulating circuit are input to an end of described amplitude comparison circuit, measured signal also is connected directly to the other end of described amplitude comparison circuit by described input, described amplitude comparison circuit compares the amplitude of two described input signals, and the control end that compare result signal is exported to described on-off circuit is with as its control signal, described on-off circuit is according to the control of this control signal, to export the outside to by described outfan from described input and via the signal of described electric current steering detection circuit input, perhaps cut off being connected of described electric current steering detection circuit and described outfan.
According to the present invention aspect first in described signal top point search device, is the square pulse signal by described electric current steering detection circuit by the signal that described on-off circuit exports described outfan to, and described square pulse signal has corresponding relation with the top point of described measured signal.
In an embodiment of the present invention, the trailing edge of described square pulse signal is corresponding to the top point of described measured signal.
In according to signal top point search device of the present invention, described measured signal is for reflecting the signal of human body physiological characteristics.
Described human body physiological characteristics signal can be an ECG signal.In this case, described input is connected to the induction apparatus of ECG signal, and the signal top point of described measurement device can be the top point of the R type ripple signal in the ECG signal at this moment.
Described human body physiological characteristics signal can also be a light change in volume trace signal.In this case, described input is connected to the induction apparatus of light change in volume trace signal, and the signal top point of described measurement device is the top point of light change in volume trace signal at this moment.
In an embodiment of the present invention, described top point testing circuit comprises first operational amplifier, second operational amplifier, diode and electric capacity,
Wherein, the in-phase input end of described first operational amplifier links to each other with the described input of described device, its inverting input links to each other with the inverting input and the outfan of described second operational amplifier, the outfan of described first operational amplifier is connected to the in-phase input end of described second operational amplifier by described diode, and the in-phase input end of described second operational amplifier is by described capacity earth.
In addition, in an embodiment of the present invention, the described outfan of described device can be connected with the external signal processor, is used for the output signal of described device is handled.
Described according to a second aspect of the invention, it provides a kind of said apparatus that utilizes to carry out the method that signal top point is searched, and this method may further comprise the steps: 1) import measured signal by the described input of described device; 2) utilize described electric current steering detection circuit to carry out electric current to measured signal and turn to detection, and export corresponding signal; And 3) from the signal of described electric current steering detection circuit output, select with the signal of the top spot correlation of measured signal and export this signal.
Described method further may further comprise the steps: the top point that 3-1) utilizes the described top point testing circuit detection measured signal of described device, the amplitude of its output signal is maintained near the point of top as far as possible, and make its output signal be close to the direct current signal of certain amplitude; 3-2) utilize the described amplitude regulating circuit of described device that the amplitude of the output signal of described top point testing circuit is regulated; 3-3) the described amplitude comparison circuit that utilizes described device compares the amplitude of the measured signal by the described input input amplitude with the output signal of described top point testing circuit, and the generation compare result signal; And 3-4) utilize described compare result signal described on-off circuit to be controlled, with conducting or cut off the signal of described electric current steering detection circuit to the described outfan output of described device as control signal.
Aspect second in the point searching method of described signal top according to the present invention, is the square pulse signal by described electric current steering detection circuit by the signal that described on-off circuit exports described outfan to, and described square pulse signal has corresponding relation with the top point of described measured signal.
In an embodiment of the present invention, the trailing edge of described square pulse signal is corresponding to the top point of described measured signal.
In according to signal of the present invention top point searching method, described measured signal is for reflecting the signal of human body physiological characteristics.
Described human body physiological characteristics signal can be an ECG signal.In this case, described input is connected to the induction apparatus of ECG signal, and the signal top point of described measurement device can be the top point of the R type ripple signal in the ECG signal at this moment.
Described measured signal can also be a light change in volume trace signal.In this case, described input is connected to the induction apparatus of light change in volume trace signal, and the signal top point of described measurement device is the top point of light change in volume trace signal at this moment.
In addition, in an embodiment of the present invention, described method further comprises the step that external signal processor that utilization links to each other with the described outfan of described device is handled the output signal of described device.
Described according to a third aspect of the present invention, it provides a kind of equipment that utilizes said apparatus to carry out blood pressure measurement, and described equipment comprises: the first signal top point search device is used for the top point of the first human body biological characteristics signal is searched; Secondary signal top point search device is used for the top point of the second human body biological characteristics signal is searched; Signal processor, be used to write down respectively time origin from the top point search result signal of described first signal top point search device and described secondary signal top point search device, calculate the lead time between two time origins, and calculate blood pressure according to described lead time.
In the described equipment according to third aspect of the present invention, the described first human body biological characteristics signal can be ECG signal, and in this case, described top point is the top point of the R type ripple signal in the ECG signal.The described second human body biological characteristics signal is a light change in volume trace signal.
Described equipment can also comprise a display, is used to show the measurement result to blood pressure.
Described equipment also includes memory body, is used to preserve required parameter of calculating blood pressure and formula.
Described equipment also can comprise finger-impu system, is used to import the required parameter of calculating blood pressure.
Described according to a fourth aspect of the present invention, it provides a kind of method of utilizing said apparatus to carry out blood pressure measurement, said method comprising the steps of: 1) utilize the described first signal top point search device that the point of the top in the ECG signal is searched; 2) utilize described secondary signal top point search device that the top point of light change in volume trace signal is searched; 3) utilize described signal processor record respectively from the time origin of the top point search result signal of described first signal top point search device and described secondary signal top point search device, calculate the lead time between two time origins; And 4) calculate blood pressure by described signal processor according to described lead time.
In the described method, the described first human body biological characteristics signal can be ECG signal aspect the 4th according to the present invention, and in this case, described top point is the top point of the R type ripple signal in the ECG signal.The described second human body biological characteristics signal is a light change in volume trace signal.
Above-mentioned steps 4) further comprises in according to being kept at the parameter in the memory body and the step of formula calculating blood pressure.
Described method also can comprise the step that shows the blood pressure that calculates.
Described method also can comprise the step of input calculating blood pressure desired parameters.
The present invention can be applicable to but is not limited to not have damaged formula, and continous way and do not have wrist strap gasbag-type sphygomanometer is utilized the later stage signal processing that carries out such as signal top searching procedure owing to simplified, so its less demanding to signal processor.Compared with prior art, the not only lower and power saving of cost of the present invention, and, owing to program is simplified, thus the also minimizing relatively of its development time, thus increase cost benefit greatly.
Description of drawings
By following detailed explanatory note also with reference to the accompanying drawings, it is clearer that above-mentioned purpose of the present invention, feature and advantage will become, in following accompanying drawing:
Fig. 1 is the circuit structure diagram according to the described signal top point of embodiment of the invention search device;
Fig. 2 is the flow chart according to the described signal of embodiment of the invention top point searching method;
Fig. 3 is the signal waveforms in the embodiment of the invention;
Fig. 4 is the structured flowchart according to the described blood pressure measurement device of the embodiment of the invention;
Fig. 5 is the FB(flow block) according to the described blood pressure measuring method of the embodiment of the invention.
The explanation of preferred embodiment
Each embodiment of the present invention is elaborated below with reference to accompanying drawing.
At first with reference to figure 1 and Fig. 3 to describing according to the described signal top point of embodiment of the invention search device.
Fig. 1 is the circuit structure diagram according to the described signal top point of embodiment of the invention search device.Fig. 3 is the signal waveforms in the embodiment of the invention.As shown in Figure 1, this device comprises: input 110, be used for receiving inputted signal, and input signal can be from ECG signal or light change in volume trace signal, and its typical signal waveform is shown in 310 among Fig. 3; The electric current steering detection circuit 120 that links to each other with input 110, comprising operational amplifier U1, resistance R 1 and capacitor C 1, this circuit is used to respond to turning to of input current, thereby output square pulse signal, the type signal waveform of the square pulse signal of its output is shown in 340 among Fig. 3, because electric current steering detection circuit 120 turns to Shi Junhui output square pulse signal at each electric current, therefore can not represent the position (310 and 340 corresponding relation from Fig. 3 as can be seen) of the top point of input signal, search the top point so need add circuit in addition; The top point testing circuit 130 that links to each other with input 110, comprise two operational amplifier U2 and U3, diode D1 and capacitor C 2 in it, this circuit is used to detect the top point of input signal and the amplitude of its output signal is maintained near the point of top as far as possible, make its output signal be close to the direct current signal of certain amplitude, its typical signal output waveform is shown in 320 among Fig. 3; With the amplitude regulating circuit 140 that the outfan of top point testing circuit 130 links to each other, be provided with a variable resistance VR1 in it, in order to the amplitude of adjusting top point signal, thereby export a kind of direct current signal through the amplitude of accommodation, its type signal waveform is shown in 330; Amplitude comparison circuit 150, be provided with an operational amplifier U4 in it, two inputs of operational amplifier U4 link to each other with the outfan and the input 110 of amplitude regulating circuit 140 respectively, circuit 150 is used for comparing through the direct current signal of amplitude adjusted and the amplitude of input signal, if the amplitude of input signal is greater than the direct current signal through amplitude adjusted, then it will export the square pulse signal, otherwise, it will make its output head grounding (that is, making outfan keep low level); On-off circuit 160, be provided with transistor Q1 in it, the two poles of the earth vacuum D2 pipe and a kind of resistance R 2, the base stage of transistor Q1 links to each other with the control end as on-off circuit 160 with the outfan of amplitude comparison circuit 140 by resistance R 2, its grid links to each other with the outfan of circuit steering detection circuit 120, its emitter stage is connected to outfan 170 by diode D2, if the signal of amplitude comparison circuit 150 outputs is square pulse signal (high level), then on-off circuit 160 is with turn-on current steering detection circuit 120 and outfan 170, if the output head grounding of amplitude comparison circuit 150 (low level), then on-off circuit 160 will cut off being connected of electric current steering detection circuit 120 and outfan 170, like this, processing through on-off circuit 160, just square pulse filtering that can those and top point in the waveform 340 shown in Figure 3 is irrelevant, thus typical waveform shown in 350 formed; And outfan 170, it can send the signal such as square pulse signal 350 to external equipment (as signal processor) to do further processing.
What the inventor drew attention to is that though with the form of particular circuit configurations embodiments of the invention have been made explanation in the above description, these explanations should not be considered to limitation of the present invention.For the person of ordinary skill of the art, above-mentioned each circuit all can have multiple known implementation method.For example, at Willis J.Tompkins and John G.Webster, EDS, " SignalProcessing-Hardware versus Software " (signal processing-hardware and software), inDesign of Microcomputer-Based Medical Instrumentation, London, Prentice-Hall International, Inc., 1981; Sergio Franco, " Nonlinear Circuits " (nonlinear circuit), in Design with Operational Amplifiers and AnalogIntegrated Circuits-2
NdEdition, New York, The McGraw-Hill Companies, 1997 and M.J.Burke, " Low-power ECG amplifier/detector fordry-electrode heart rate monitoring " (the low power ECG amplifier/detector that is used for dried electrode rhythm of the heart), Medical ﹠amp; Biological Engineering ﹠amp; Computing, vol.32, pp.678-83 has just put down in writing the example of some specific implementations of above-mentioned each circuit in 1994 lists of references such as grade.
Next will be with reference to figure 1, Fig. 2 and Fig. 3 to describing according to the described signal of embodiment of the invention top point searching method.
Fig. 2 is the flow chart according to the described signal of embodiment of the invention top point searching method.As shown in Figure 2, at first, in step 210, measured signal is transfused to, and the measured signal of being imported can be from ECG signal or light change in volume trace signal, and its type signal waveform is shown in 310 among Fig. 3.Then, in step 220, measured signal is input to circuit steering detection circuit 120 (see figure 1)s, and in step 230, be subjected to electric current and turn to detection, along with electric current produces turning to as waveform 310, steering detection circuit 120 will correspondingly be exported the square pulse signal to on-off circuit 160, and its typical waveform is shown in 340.Because turning to all at each electric current, circuit steering detection circuit 120 can export the square pulse signal, therefore these signals can not be represented the position of the top point of input signal, so need do further filtration to these signals, with the irrelevant square pulse signal of filtering those and top point.Meanwhile, measured signal also is input to top point testing circuit 130, and in step 240, top point testing circuit 130 top point to measured signal detects, and output top point signal.Then, in step 250, the amplitude of the top point signal of top point testing circuit 130 outputs is subjected to the adjusting of amplitude regulating circuit 140, and is output to amplitude comparison circuit 150.In step 260, amplitude comparison circuit 150 to measured signal amplitude and the amplitude of the output signal of amplitude regulating circuit compare, and according to control signal of comparative result output.Circuit steering detection circuit 120 will correspondingly be communicated with under the control of this control signal or be cut off with outfan 170, specifically, if the amplitude of measured signal is greater than the amplitude of the output signal of amplitude regulating circuit, then on-off circuit 160 conductings, and then the output (step 270) of open circuit steering detection circuit, otherwise then on-off circuit cuts out, and then the output (step 280) of shut-off circuit steering detection circuit.At last, measurement signals (having the signal waveform shown in 350) is output to the external equipment (step 290) such as signal processor by outfan 170.
The purpose of above-mentioned steps 240 to 260 is for the irrelevant signal of filtering the square pulse signal of being exported from the electric current steering detection circuit those and top point.But those of ordinary skill in the art should be understood that the technological means of the non-top point signal of filtering is not limited in above-mentioned concrete grammar.For example, also can adopt low pass and high pass filter to carry out the method for filtering.Because ECG signal and light change in volume trace signal are in the only all procuratorial work of making top point of the present invention, its effective spectrum that applies to is greatly between 0.5 hertz to 30 hertz.And therefore the frequency spectrum of noise, can adopt low pass and high pass filter the noise-filtering of non-signal mostly near direct current or 50 hertz.But the design reference example of low pass and high pass filter such as following document: Sergio Franco, " ActiveFilters:Part I " (active filter: chapter 1), in Design with Operational Amplifiersand Analog Integrated Circuits-2
NdEdition, New York, The McGraw-HillCompanies, 1997.
Application in blood pressure measurement describes to device of the present invention below with reference to Fig. 4 and Fig. 5.
Fig. 4 is the structural representation block diagram according to the described blood pressure measurement device of the embodiment of the invention.As shown in Figure 4, a kind of according to blood pressure measurement device of the present invention mainly by two top of the present invention point measurement devices 430 and 440 and signal processor 450 form.Device 430 can be used for measuring its top point by the collected ECG signal of ECG signal induction apparatus 410, and exports the correct time of its top point to signal processor 450 with a reference index as blood pressure measurement.When determining the correct time of top point, the top point that can adopt the R type ripple signal in the ECG signal is as basic point.Circuit 440 of the present invention can be used for measuring the top point by the collected light change in volume trace signal of light change in volume trace signal induction apparatus 420, and exports the correct time of its top point to signal processor 450 with another reference index as blood pressure measurement.When determining the correct time of top point, the top point that can adopt light change in volume trace signal is as basic point.In addition, when adopting above-mentioned top point, can adopt the time location of the decline edgewise (seeing 360 among Fig. 3) of the square pulse signal that apparatus of the present invention export as the top point of input signal as the basic point of measurement blood pressure.The correct time of signal processor 450 use devices 430 and 440 collected signal top points is respectively as basic point, calculate two time differences between time origin, and utilize blood pressure and the corresponding dependency relation of pulse delivery time (that is above-mentioned time difference) to calculate blood pressure.Can comprise also that according to the described blood pressure measurement device of present embodiment for example: input keyboard 470 is used for to the required parameter of signal processor 450 manual input blood pressure measurements; Memory body 460 is used to store and carries out required parameter of blood pressure measurement and computing formula; And display 480, be used for reporting the result of blood pressure measurement to user or medical worker, or the like.Because these parts all are known to those skilled in the art, so repeat no more.
Fig. 5 is the FB(flow block) according to the described blood pressure measuring method of the embodiment of the invention.As shown in Figure 5, when utilization present device is as shown in Figure 4 carried out blood pressure measurement, in step 510, at first carry out the top detection algorithm, promptly, utilize 450 pairs of top pulses of signal processor to carry out computing, to calculate the top point time location of ECG signal and light change in volume trace signal with the top pulse 290 of light change in volume trace signal by circuit 430 of the present invention or 440 ECG signal of being exported.Then, in step 520, signal processor 450 according to the time difference between ECG signal and the light change in volume trace signal to determine the value of pulse delivery time.Next, in step 530, whether the sum of 450 pairs of pulse delivery times of signal processor reaches default value (for example 10) is made judgement.Use the single pulse delivery time to go to determine blood pressure can have many unsettled factors, thereby increase the error that blood pressure detects.Be based on the meansigma methods of 10 pulse delivery times in the present invention.Step 530 is to be repeated until that 10 pulse delivery times are detected.Next step, in step 540, signal processor 450 is transferred the equation of surveying earlier according to pushing up in internal memory 460, and the average pulse delivery time of utilizing step 530 to calculate, thereby calculates systolic pressure, mean pressure and diastolic pressure.At the decision systolic pressure, after mean pressure and the diastolic pressure, numerical value is sent to step 550.In step 550, if pressure value (for example systolic pressure is greater than 240mmHg) not in range of normal value, then processor 450 will send error message in step 560.The systolic pressure that calculates, mean pressure and diastolic pressure can be revealed by display 480, also can be transmitted to far-end by the communicator such as radio transmitting device so that further handle.Other if desired blood pressure measurement, then step 570 is with repeating step 510,520,530,540,550 and 560.
Claims (27)
1. signal top point search device comprises:
Input is used to import measured signal;
The electric current steering detection circuit is used for exporting corresponding signal according to the input current direction of measured signal;
Point testing circuit in top is used to detect the top point of measured signal, the amplitude of its output signal is maintained near the point of top as far as possible, and make its output signal be close to the direct current signal of certain amplitude;
Amplitude regulating circuit, the amplitude that is used to regulate its input signal;
The amplitude comparison circuit is used for the amplitude of its input signal is compared, and exports corresponding signal according to comparative result;
On-off circuit is used for making under the control of control signal its signal that passes through to be switched on or to cut off; And
Outfan is used for exporting signal to outside,
Wherein, measured signal is by described input, described top point testing circuit and described amplitude regulating circuit are input to an end of described amplitude comparison circuit, measured signal also is connected directly to the other end of described amplitude comparison circuit by described input, described amplitude comparison circuit compares the amplitude of two described input signals, and the control end that compare result signal is exported to described on-off circuit is with as its control signal, described on-off circuit is according to the control of this control signal, to export the outside to by described outfan from described input and via the signal of described electric current steering detection circuit input, perhaps cut off being connected of described electric current steering detection circuit and described outfan.
2. device according to claim 1, it is characterized in that, is the square pulse signal by described electric current steering detection circuit by the signal that described on-off circuit exports described outfan to, and described square pulse signal has corresponding relation with the top point of described measured signal.
3. device according to claim 2, it is characterized in that, when the ratio of the amplitude of the pairing described measured signal extreme point of the trailing edge of described square pulse signal and the amplitude of described measured signal top point equaled or exceeded predetermined ratio, the extreme point of this trailing edge correspondence of described square pulse signal was considered as the top point of described measured signal.
4. device according to claim 1 is characterized in that, described measured signal is for reflecting the signal of human body physiological characteristics.
5. device according to claim 4 is characterized in that, described human body physiological characteristics signal is an ECG signal.
6. device according to claim 5 is characterized in that described input is connected to the induction apparatus of ECG signal, and the signal top point of described measurement device is the top point of the R type ripple signal in the ECG signal at this moment.
7. device according to claim 4 is characterized in that, described human body physiological characteristics signal is a light change in volume trace signal.
8. device according to claim 7 is characterized in that described input is connected to the induction apparatus of light change in volume trace signal, and the signal top point of described measurement device is the top point of light change in volume trace signal at this moment.
9. device according to claim 1 is characterized in that, described top point testing circuit comprises first operational amplifier, second operational amplifier, diode and electric capacity,
Wherein, the in-phase input end of described first operational amplifier links to each other with the described input of described device, its inverting input links to each other with the inverting input and the outfan of described second operational amplifier, the outfan of described first operational amplifier is connected to the in-phase input end of described second operational amplifier by described diode, and the in-phase input end of described second operational amplifier is by described capacity earth.
10. device according to claim 1 is characterized in that, the described outfan of described device is connected to a signal processor, and this signal processor is used for the output signal of described device is handled.
11. one kind is utilized the described device of claim 1 to carry out the method that signal top point is searched, may further comprise the steps:
1) imports measured signal by the described input of described device;
2) utilize described electric current steering detection circuit to carry out electric current to measured signal and turn to detection, and export corresponding signal; And
3) from the signal of described electric current steering detection circuit output, select with the signal of the top spot correlation of measured signal and export this signal.
12. method according to claim 11 is characterized in that described step 3) further may further comprise the steps:
3-1) utilize the described top point testing circuit of described device to detect the top point of measured signal, the amplitude of its output signal is maintained near the point of top as far as possible, and make its output signal be close to the direct current signal of certain amplitude;
3-2) utilize the described amplitude regulating circuit of described device that the amplitude of the output signal of described top point testing circuit is regulated;
3-3) the described amplitude comparison circuit that utilizes described device compares the amplitude of the measured signal by the described input input amplitude with the output signal of described top point testing circuit, and the generation compare result signal; And
3-4) utilize described compare result signal described on-off circuit to be controlled, with conducting or cut off the signal of described electric current steering detection circuit to the described outfan output of described device as control signal.
13. method according to claim 12, it is characterized in that, is the square pulse signal by described electric current steering detection circuit by the signal that described on-off circuit exports described outfan to, and described square pulse signal has corresponding relation with the top point of described measured signal.
14. method according to claim 13, it is characterized in that, when the ratio of the amplitude of the pairing described measured signal extreme point of the trailing edge of described square pulse signal and the amplitude of described measured signal top point equaled or exceeded predetermined ratio, the extreme point of this trailing edge correspondence of described square pulse signal was considered as the top point of described measured signal.
15. method according to claim 11 is characterized in that, described measured signal is for reflecting the signal of human body physiological characteristics.
16. method according to claim 15 is characterized in that, described human body physiological characteristics signal is an ECG signal.
17. method according to claim 16 is characterized in that, described input is connected to the induction apparatus of ECG signal, and the signal top point of described measurement device is the top point of the R type ripple signal in the ECG signal at this moment.
18. method according to claim 15 is characterized in that, described measured signal is a light change in volume trace signal.
19. method according to claim 18 is characterized in that, described input is connected to the induction apparatus of light change in volume trace signal, and the signal top point of described measurement device is the top point of light change in volume trace signal at this moment.
20. method according to claim 11 is characterized in that the step that external signal processor that described method comprises that further utilization links to each other with the described outfan of described device is handled the output signal of described device.
21. an equipment that utilizes the described device of claim 1 to carry out blood pressure measurement comprises:
The first signal top point search device is used for the top point of the first human body biological characteristics signal is searched;
Secondary signal top point search device is used for the top point of the second human body biological characteristics signal is searched; And
Signal processor, be used to write down respectively time origin from the top point search result signal of described first signal top point search device and described secondary signal top point search device, calculate the lead time between two time origins, and calculate blood pressure according to described lead time.
22. equipment according to claim 21 is characterized in that, the described first human body biological characteristics signal is an ECG signal.
23. equipment according to claim 22 is characterized in that, described top point is the top point of the R type ripple signal in the described ECG signal.
24. equipment according to claim 21 is characterized in that, the described second human body biological characteristics signal is a light change in volume trace signal.
25. equipment according to claim 21 is characterized in that, described equipment also comprises a display that is connected with described signal processor, is used to show the measurement result to blood pressure.
26. equipment according to claim 21 is characterized in that, described equipment also includes memory body, is used to preserve required parameter of calculating blood pressure and formula.
27. equipment according to claim 21 is characterized in that, described equipment also comprises finger-impu system, is used to import the required parameter of calculating blood pressure.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031366597A CN1307937C (en) | 2003-05-22 | 2003-05-22 | Signal top searcher and searching method and application in blood pressure measurement |
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| CNB031366597A CN1307937C (en) | 2003-05-22 | 2003-05-22 | Signal top searcher and searching method and application in blood pressure measurement |
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| CN1548006A CN1548006A (en) | 2004-11-24 |
| CN1307937C true CN1307937C (en) | 2007-04-04 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1985750B (en) * | 2005-12-21 | 2011-03-23 | 深圳迈瑞生物医疗电子股份有限公司 | Pulse wave detecting method and device by means of cardiac symbol signal |
| WO2009125811A1 (en) * | 2008-04-09 | 2009-10-15 | 旭化成株式会社 | Blood pressure estimating device and blood pressure estimating method |
| US10758143B2 (en) | 2015-11-26 | 2020-09-01 | Huawei Technologies Co., Ltd. | Blood pressure parameter detection method and user equipment |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86102111A (en) * | 1985-04-01 | 1987-02-04 | 耐尔科公司 | Detect improving one's methods and installing of light pulse |
| JPH0489029A (en) * | 1990-08-02 | 1992-03-23 | Sony Corp | Blood pressure measuring device |
| JPH08583A (en) * | 1994-06-22 | 1996-01-09 | Minolta Co Ltd | Apparatus for monitoring pulse wave transmission time |
-
2003
- 2003-05-22 CN CNB031366597A patent/CN1307937C/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86102111A (en) * | 1985-04-01 | 1987-02-04 | 耐尔科公司 | Detect improving one's methods and installing of light pulse |
| JPH0489029A (en) * | 1990-08-02 | 1992-03-23 | Sony Corp | Blood pressure measuring device |
| JPH08583A (en) * | 1994-06-22 | 1996-01-09 | Minolta Co Ltd | Apparatus for monitoring pulse wave transmission time |
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| CN1548006A (en) | 2004-11-24 |
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