CN1299718C - Medicine for treating cardio-cerebral vascular disease and its preparing method - Google Patents
Medicine for treating cardio-cerebral vascular disease and its preparing method Download PDFInfo
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- CN1299718C CN1299718C CNB2005100513959A CN200510051395A CN1299718C CN 1299718 C CN1299718 C CN 1299718C CN B2005100513959 A CNB2005100513959 A CN B2005100513959A CN 200510051395 A CN200510051395 A CN 200510051395A CN 1299718 C CN1299718 C CN 1299718C
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Abstract
The present invention discloses a medicine for treating cardiovascular/cerebrovascular diseases. The present invention is composed of glossy ganoderma, tuckahoe, hirudo, peach kernels, tree peony bark, herba cistanches, dogwood fruits, RADIX MORINDAE OFFICINALIS, astragalus roots and sallow thorn oil. The present invention has the functions of activating the blood circulation to dissipate blood stasis, nourishing the liver and kidney, reducing blood lipid, clearing oxyradicals and improving myocardial ischemia, has no stimulation to gastrointestinal tracts, has obvious improving effects on renal functions, and is a medicine for treating both manifestations and root causes of diseases, which is suitable for any patient who has the cardiovascular/cerebrovascular diseases.
Description
Technical field:
The present invention relates to a kind of medicine for the treatment of cardiovascular and cerebrovascular disease and preparation method thereof, belong to technical field of Chinese medicines.
Background technology:
Cardiovascular and cerebrovascular disease is first killer of harm humans health, data show according to World Health Organization's announcement, cardiovascular and cerebrovascular disease has become first killer of harm humans health, at present, China has 1.1 hundred million people to suffer from cardiovascular and cerebrovascular diseases such as hypertension, arteriosclerosis approximately, and 6,000 ten thousand people suffer from coronary heart disease, and 7,000 ten thousand people suffer from cerebral infarction or cerebral hemorrhage, philtrum more than 40 years old has 57% people to suffer from various degree cardiovascular and cerebrovascular disease approximately.And cardiovascular and cerebrovascular disease (as apoplexy, cerebral hemorrhage, heart infarction, coronary heart disease) premorbid has the characteristics of high mortality, high relapse rate, high disability rate concurrently without any sign, brings huge misery for countless families.
The Chinese medicine for the treatment of cardiovascular and cerebrovascular disease in the market is too many, all exists treatment time long, and some medicine need be taken all the life, cure rate is low, and easily recurrence has the zest effect to gastrointestinal function, their mechanism of action all is at its treatment of conditions, and its cause of disease is not taked conditioning and treating.
Summary of the invention
Theory of Chinese medical science thinks that the true cause of cardiovascular and cerebrovascular disease morbidity is the vigour loss, and cardiovascular and cerebrovascular disease is not common disease, but a kind of naturally-aged symptom that the loss of human body vigour causes, therefore replenishing vigour is the only way.In order to overcome the deficiency of the existing medicine in market to the treatment cardiovascular and cerebrovascular disease, in order to make the more cardiovascular and cerebrovascular disease patient can rehabilitation, the inventor is based on theory of Chinese medical science, from Chinese crude drug, chosen have invigorate blood circulation, Chinese crude drug that blood stasis dispelling nourishing the liver and kidney, blood fat reducing are removed the oxyradical effect, make medicine of the present invention.
The objective of the invention is to disclose a kind of Chinese medicinal components for the treatment of the medicine of cardiovascular and cerebrovascular disease.
Another object of the present invention is to provide the preparation method of this medicine.
Medicine of the present invention is chosen 10 kinds of Chinese medicines and is made up, and these 10 kinds of Chinese medicines are made up of Ganoderma lucidum seu Japonicum, Poria, Hirudo, Semen Persicae, Cortex Moutan, Herba Cistanches, Fructus Corni, Radix Morindae Officinalis, the Radix Astragali and Oleum Hippophae.
The inventor has determined that the amount ranges of each component of medicine of the present invention is as follows through constantly groping:
Ganoderma lucidum seu Japonicum 10g-150g, Poria 8g-90g, Hirudo 5g-90g, Semen Persicae 10g-120g, Cortex Moutan 6g-80g, Radix Morindae Officinalis 12g-100g, Herba Cistanches 15g-120g, Radix Astragali 15g-180g, Oleum Hippophae 15g-200g, Fructus Corni 15g-150g.
Wherein the preferred amount ranges of each component is: Ganoderma lucidum seu Japonicum 20g-120g, Poria 15g-75g, Hirudo 15g-70g, Semen Persicae 25g-100g, Cortex Moutan 15g-70g, Radix Morindae Officinalis 20g-80g, Herba Cistanches 20g-100g, Radix Astragali 30g-150g, Oleum Hippophae 25g-150g, Fructus Corni 20g-120g.
Wherein the optimum amount scope of each component is: Ganoderma lucidum seu Japonicum 60g-115g, Poria 35g-60g, Hirudo 45g-70g, Semen Persicae 50g-90g, Cortex Moutan 45g-70g, Radix Morindae Officinalis 40g-65g, Herba Cistanches 60g-70g, Radix Astragali 65g-120g, Oleum Hippophae 50g-90g, Fructus Corni 50g-90g.
Wherein the optimum amount of each component is: Ganoderma lucidum seu Japonicum 100g, Poria 50g, Hirudo 65g, Semen Persicae 80g, Cortex Moutan 65g, Radix Morindae Officinalis 65g, Herba Cistanches 70g, Radix Astragali 90g, Oleum Hippophae 80g, Fructus Corni 80g.
The preparation method of medicine of the present invention is as follows:
(1), with described Ganoderma lucidum seu Japonicum, Poria, Hirudo, Semen Persicae, Cortex Moutan, Radix Morindae Officinalis, Herba Cistanches, the Radix Astragali, Fructus Corni, pulverize, through the screening of 180 order square-bottomed bamboo baskets, collect medicated powder then, carry out irradiation sterilization with cobalt-60 gamma ray;
(2), Oleum Hippophae sneaked in the step 1 in the medicated powder of collecting stir evenly, fill capsule, carry out irradiation sterilization with cobalt-60 gamma ray, bottle.
10 kinds of Chinese medicines of choice of drug of the present invention:
Ganoderma property of medicine tepor, sweet in the mouth, the effect that nourishing blood to tranquillize the mind, invigorating the spleen and regulating the stomach are arranged, its main component triterpenes can suppress cholesterol absorption, and rate-limiting enzyme 3 hydroxyls 3 methyl glutaryl coenzyme A reductases in the inhibition cholesterol building-up process, and it is synthetic therefore to suppress cholesterol, can also reduce and contain blood viscosity and plasma viscosity, the blood flow when making cardiovascular and cerebrovascular disease is learned obstacle and is improved;
Poria is flat, slightly sweet flavor, and the effect of promoting diuresis to eliminate damp pathogen, invigorating spleen and reinforcing stomach, mind tranquilizing and the heart calming is arranged;
Hirudo property is flat, salty in the mouth is bitter, and the effect of removing blood stasis, blood fat reducing is arranged, and its main component hirudin can suppress hematoblastic hypertrophy in the blood, thereby reduces whole blood viscosity;
Semen Persicae is flat, sweet-bitter flavor, and the effect of blood circulation promoting and blood stasis dispelling, laxation relieving constipation is arranged, and contained Semen Armeniacae Amarum glycoside, emulsin etc. have anticoagulant and more weak haemolysis, and blood volume retardance, the capable obstacle of blood are had the improvement effect, energy cerebral blood flow increasing amount;
Cortex Moutan cold nature, bitter in the mouth suffering have clearing away heat and cooling blood, removing heat from blood to move back the effect of steaming, promoting blood circulation to remove blood stasis;
Warm in nature, the sweet-salty of Herba Cistanches has the effect of reinforcing the kidney and supporting YANG, loosening bowel to relieve constipation, and contained micro-alkaloid etc. have obvious hypotensive effect and study of anti-atherogenic effect;
Fructus Corni slightly warm in nature, sour in the mouth have liver and kidney tonifying, the astringent or styptic treatment for spontaneous sweating effect of convergence, and its main component Saponin, malic acid, tartaric acid etc. have the diuresis hypotensive effect;
The Radix Morindae Officinalis slightly warm in nature, acrid in the mouth, sweet has the effect of reinforcing the kidney and supporting YANG, expelling wind and removing dampness, and contained flavone compound has effect of corticoid sample and study of anti-atherogenic effect;
Warm in nature, the sweet in the mouth of the Radix Astragali has the effect of all empty deficiencies, beneficial vigour, strong taste, the hemopoietic of invigorating blood circulation, and its contained astragalus polysaccharides can increase immunologic function, protection cardiovascular system, and astragalus saponin 1 has the effect of blood pressure lowering;
Warm in nature, the sour-puckery flavor of Oleum Hippophae, the effect that promoting blood circulation to remove blood stasis, eliminating phlegm and stopping cough, relieving dyspepsia are arranged, its main component Fructus Hippophae flavone has the effect that improves oxyradical in body immunity, defying age, the removing human body, can suppress cholesterol absorption, improve cardiac muscle, improve the resistance of cardiac muscle, increase coronary blood-flow volume, improve myocardium microcirculation ischemia, anticoagulant, prevent thrombosis, blood fat reducing alleviates the arteriosclerosis degree.
Medicine of the present invention is a monarch drug with Herba Cistanches, Radix Morindae Officinalis, the Fructus Corni that invigorating the liver and kidney, the smart effect of benefit are arranged; So that oxyradical in blood circulation promoting and blood stasis dispelling, blood fat reducing, blood pressure lowering, the removing human body, anticoagulant, the Ganoderma lucidum seu Japonicum of reduction whole blood viscosity effect, Hirudo, Semen Persicae, Cortex Moutan, Oleum Hippophae to be arranged is ministerial drug; With the Poria that promoting diuresis to eliminate damp pathogen, invigorating spleen and reinforcing stomach, mind tranquilizing and the heart calming, regulating fluid apssage effect are arranged is messenger drug; The Radix Astragali with the first effect of useful essence is an adjuvant drug.
No a kind of medicine that takes stopgap measures and effect a permanent cure in the medicine of at present numerous treatment cardiovascular and cerebrovascular diseases on the market, the effect that this medical instrument has nourishing the liver and kidney, blood fat reducing, blood circulation promoting and blood stasis dispelling, improves myocardial ischemia, softens arterial sclerosis, function by conditioning internal organs nourishing the liver and kidney, balance patient's negative and positive, treat cardiovascular and cerebrovascular disease and reach effect and the medicine of the present invention that effects a permanent cure that take stopgap measures gastrointestinal tract is had no stimulation, the improvement to renal function has obvious effect in addition.
The specific embodiment
Below by testing the beneficial effect that example illustrates that medicine of the present invention (to call " heart and brain return heart-soothing capsule " in the following text) is had, this test example is the clinical efficacy test of medicine of the present invention
[test example]
1, physical data
Accept patient's 300 examples for medical treatment, wherein each 100 example of apoplexy patient, heart patient and hyperlipidemia patient.
2, diagnostic criteria
The apoplexy patient: the sound words are unfavorable, hemianesthesia is unable, row foot difficulty.
Heart disease patient's (various coronary heart disease): cardiopalmus, breathe hard, uncomfortable in chest, chest pain, insomnia and dreamful sleep.
Hyperlipidemia patient: dizzy, headache.
3, Therapeutic Method
Oral, three times on the one, one time three to five or follow the doctor's advice, empty clothes, one month is a course of treatment.
4, efficacy assessment standard
Apoplexy patient's various transference cures are for curing.
Heart disease patient's electrocardiogram, kinetocardiography are normally for curing.
The liquefaction of hyperlipidemia patient menses is tested, and blood fat is reduced to normal value for curing.
5, therapeutic outcome
300 patients take heart and brain and returned heart-soothing capsule three months, and therapeutic outcome is as follows:
Early stage apoplexy patient, effective percentage 100%, cure rate 90.2%;
Apoplexy patient more than 2 years, effective percentage 100%, cure rate 67.8%;
The heart disease patient, effective percentage 100%, cure rate 88.7%;
The hypertensive patient, effective percentage 100%, cure rate 91.4%.
The preparation of medicine of the present invention is described by the following examples.
[embodiment]
(1), takes by weighing Ganoderma lucidum seu Japonicum 100g, Poria 50g, Hirudo 65g, Semen Persicae 80g, Cortex Moutan 65g, Radix Morindae Officinalis 65g, Herba Cistanches 70g, Radix Astragali 90g, Oleum Hippophae 80g, Fructus Corni 80g;
(2), 9 kinds of Chinese medicines except that Oleum Hippophae in (1) are pulverized, with the screening of 180 order square-bottomed bamboo baskets, collection medicated powder carries out irradiation sterilization with cobalt-60 gamma ray;
(3), Oleum Hippophae is sneaked in the medicated powder in the step (2), fully stir evenly, fill capsule, carry out irradiation sterilization with cobalt-60 gamma ray, bottling.
Claims (5)
1, a kind of medicine for the treatment of cardiovascular and cerebrovascular disease is characterized in that the raw material composition of making effective ingredient is by weight ratio: Ganoderma lucidum seu Japonicum 10g-150g, Poria 8g-90g, Hirudo 5g-90g, Semen Persicae 10g-120g, Cortex Moutan 6g-80g, Radix Morindae Officinalis 12g-100g, Herba Cistanches 15g-120g, Radix Astragali 15g-180g, Oleum Hippophae 15g-200g, Fructus Corni 15g-150g.
2, a kind of medicine for the treatment of cardiovascular and cerebrovascular disease according to claim 1, wherein the weight proportion of each crude drug is: Ganoderma lucidum seu Japonicum 20g-120g, Poria 15g-75g, Hirudo 15g-70g, Semen Persicae 25g-100g, Cortex Moutan 15g-70g, Radix Morindae Officinalis 20g-80g, Herba Cistanches 20g-100g, Radix Astragali 30g-150g, Oleum Hippophae 25g-150g, Fructus Corni 20g-120g.
3, a kind of medicine for the treatment of cardiovascular and cerebrovascular disease according to claim 1, wherein the weight proportion of each crude drug is: Ganoderma lucidum seu Japonicum 60g-115g, Poria 35g-60g, Hirudo 45g-70g, Semen Persicae 50g-90g, Cortex Moutan 45g-70g, Radix Morindae Officinalis 40g-65g, Herba Cistanches 60g-70g, Radix Astragali 65g-120g, Oleum Hippophae 50g-90g, Fructus Corni 50g-90g.
4, a kind of medicine for the treatment of cardiovascular and cerebrovascular disease according to claim 1, wherein the weight proportion of each crude drug is: Ganoderma lucidum seu Japonicum 100g, Poria 50g, Hirudo 65g, Semen Persicae 80g, Cortex Moutan 65g, Radix Morindae Officinalis 65g, Herba Cistanches 70g, Radix Astragali 90g, Oleum Hippophae 80g, Fructus Corni 80g.
5, the described a kind of preparation method for the treatment of the medicine of cardiovascular and cerebrovascular disease of claim 1, it is made up of following steps:
(1), with described Ganoderma lucidum seu Japonicum, Poria, Hirudo, Semen Persicae, Cortex Moutan, Radix Morindae Officinalis, Herba Cistanches, the Radix Astragali, Fructus Corni, pulverize, through the screening of 180 order square-bottomed bamboo baskets, collect medicated powder then, carry out irradiation sterilization with the gamma ray of cobalt-60;
(2), Oleum Hippophae sneaked in the step 1 in the medicated powder of collecting stir evenly, fill capsule, carry out irradiation sterilization with the gamma ray of cobalt-60, bottle.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2005100513959A CN1299718C (en) | 2005-03-10 | 2005-03-10 | Medicine for treating cardio-cerebral vascular disease and its preparing method |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2005100513959A CN1299718C (en) | 2005-03-10 | 2005-03-10 | Medicine for treating cardio-cerebral vascular disease and its preparing method |
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| CN1682996A CN1682996A (en) | 2005-10-19 |
| CN1299718C true CN1299718C (en) | 2007-02-14 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105076586A (en) * | 2014-05-15 | 2015-11-25 | 钱如力 | A Polypeptide lucid ganoderma tea and preparation method thereof |
| CN106350224A (en) * | 2016-08-31 | 2017-01-25 | 镇雄县益雄药业有限公司 | Compound blood pressure reducing peony oil |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1224614A (en) * | 1998-01-24 | 1999-08-04 | 倪德贵 | Medicine for preventing and curing cardiac and cerebral vascular diseases and its preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1224614A (en) * | 1998-01-24 | 1999-08-04 | 倪德贵 | Medicine for preventing and curing cardiac and cerebral vascular diseases and its preparation |
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