CN1299640C - Bioelectrical detection circuit - Google Patents

Bioelectrical detection circuit Download PDF

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Publication number
CN1299640C
CN1299640C CNB2004100727898A CN200410072789A CN1299640C CN 1299640 C CN1299640 C CN 1299640C CN B2004100727898 A CNB2004100727898 A CN B2004100727898A CN 200410072789 A CN200410072789 A CN 200410072789A CN 1299640 C CN1299640 C CN 1299640C
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China
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bioelectrical
differential amplifier
common
parallel
circuit
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Expired - Fee Related
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CNB2004100727898A
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Chinese (zh)
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CN1608585A (en
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林凌
李刚
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Tianjin University
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Tianjin University
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Abstract

The present invention discloses a bioelectrical detection circuit and a detection method thereof, which belongs to the field of bioelectrical detection. The present invention particularly relates to a bioelectrical measuring technique applied to a medical instrument. The bioelectrical detection circuit comprises electrodes, an input protective circuit, a parallel connection differential amplifier, a right leg driving circuit, a sigma-delta type analog-to-digital converter and a microprocessing unit (CPU), wherein the electrodes are orderly connected by a conducting wire to be used for collecting a bioelectrical signal; the input protective circuit has functions of overvoltage protection and simple wave filtration; the parallel connection differential amplifier is provided with a common mode driver. The bioelectrical detection circuit of the present invention simultaneously uses a high common mode rejection ratio of the parallel connection differential amplifier provided with the common mode driver, a high common mode rejection ratio of the sigma-delta type analog-to-digital converter and detection bioelectricity with high resolution and high quality. The present invention has the advantages of simple structure, no need of debugging, and good performance.

Description

Bioelectrical detection circuit
Technical field
The present invention relates to the bio electricity detection range, especially be applied in the bioelectric measurement technology on the Medical Instruments.
Background technology
Bioelectric detection has important use and is worth in medical research and clinical diagnosis.But because bioelectrical signals is faint, usually have various serious interfering signals again, many people are still in the research of detection method of carrying out bioelectrical signals and circuit.People such as Liu Song have proposed a kind of monitor ecg amplifier (health care equipment the 2nd phase of .1995,3~6), (High-quality recording of bio-electric events.Med.﹠amp such as A.C.MettingVan Riji; Bio.Eng.﹠amp; Comput., 1990, (Rapid recovery physiological preamplifier withoutAC coupling capacitor.Med.﹠amp such as 28:389-397, D.W.McRobbie; Bio.Eng.﹠amp; Comput., 1990, (I.A.Dotsinsky, et al., Multi-channel DC amplifier for a microprocessor electrocardiograph.Med.﹠amp such as 28:198-200; Bio.Eng.﹠amp; Comput., 1991,29:324-329) design of multiple bioelectrical signals detecting amplifier or circuit has been proposed also.Li Gangs etc. have proposed multiple bioelectric amplifier (a kind of design of low-noise preamplifier, Chinese medical apparatus magazine, the 13rd the 1st phase of volume, 1989:18-19; 12 lead the research of D/AC feedback-type ecg signal amplifier, Chinese journal of scientific instrument, the 21st the 5th phase of volume, pp124-126, in October, 2000; High-performance multichannel bioelectric amplifier, University Of Tianjin's journal, the 33rd the 5th phase of volume, in JIUYUE, 2000; High common mode rejection ratio preamplifier, Chinese patent, application number: 02129065.2).
There are problems such as complex structure, manufacturability difference and performance be still not ideal enough in varying degrees in above-mentioned various forms of bioelectric amplifier.
Summary of the invention
Technical problem to be solved by this invention is, overcome above-mentioned the deficiencies in the prior art, a kind of bioelectrical detection circuit based on ∑-Δ pattern number converter is provided, circuit is simple, dynamic range is big, input impedance is high, need not debugging, good manufacturability, excellent performance.
In order to solve the problems of the technologies described above be, bioelectrical detection circuit of the present invention comprises the electrode that is used to gather bioelectrical signals that connects successively by lead, have the input protection circuit of overvoltage protection and simple filter function, have differential amplifier in parallel, ∑-Δ pattern number converter that common mode drives and the microprocessor CPU that has the digital spectrum compensation program, is connected with driven-right-leg circuit between described electrode and the described differential amplifier in parallel; Described ∑-Δ pattern number converter is used for mimic bioelectrical signals is converted to high-resolution digital signal.
Described driven-right-leg circuit is made of operational amplifier A 4, resistance R 5, R6 and capacitor C 3, is used for the anti-phase driving public electrode of the common-mode signal of described differential amplifier in parallel, with further inhibition common-mode signal.
Described differential amplifier in parallel is made of operational amplifier A 1 and A2, the resistance R 1 of two similar resistance and R2 and operational amplifier A 3 constitute common-mode signal and extract drive circuit, and the output signal that common-mode signal is extracted drive circuit exports described driven-right-leg circuit to.Be connected with high pass filter between described differential amplifier in parallel and described ∑-Δ pattern number converter, high pass filter is made up of capacitor C 1 and C2, resistance R 3 and R4, is used to suppress the interference of polarizing voltage and baseline drift; The output signal of common-mode signal extraction drive circuit exports the resistance R 3 of described high pass filter, the common port of R4 in the described differential amplifier in parallel.
Compared with prior art, the present invention has following beneficial effect: (one) structure of the present invention very simply, need not debugging, excellent performance and manufacturability be fabulous; (2) because differential amplifier in parallel has infinitely-great common mode rejection ratio in theory when differential output, side circuit also has very high common mode rejection ratio, and adopting ∑-Δ pattern number converter also to have very high common mode rejection ratio with differential input, both constitute perfect cooperation like this; (3) between differential amplifier in parallel and ∑-Δ pattern number converter, add high pass filter, suppressed direct current and intrasonic interference such as polarizing voltage and baseline drift; (4) constitute common-mode signal by resistance R 1 and R2 and operational amplifier A 3 and extract drive circuit, can be very poor in the Circuit Matching precision, even their appearance value or resistance differ several times situation under can both guarantee very high common mode rejection ratio, reduced circuit to the requirement of components and parts with simplified technology.
Description of drawings
Fig. 1 is a bioelectrical detection circuit schematic diagram of the present invention;
Reference numeral:
1 is that electrode 2 is differential amplifier in parallel for the line 3 that leads for input protection circuit 4
5 is that ∑-Δ pattern number converter 6 is driven-right-leg circuit for microprocessor CPU 7
The specific embodiment
Below in conjunction with accompanying drawing the present invention is elaborated.
The embodiment one of bioelectrical detection circuit of the present invention:
As shown in Figure 1; bioelectrical detection circuit comprises electrode 1, the line 2 that leads, input protection circuit 3, have differential amplifier in parallel 4, ∑-Δ pattern number converter 5, microprocessor 6 and driven-right-leg circuit 7 that common mode drives, and above-mentioned building block connects successively by lead.Wherein electrode 1 is used to gather bioelectrical signals; input protection circuit 3 has overvoltage protection and simple filter function; differential amplifier in parallel with common mode driving constitutes differential amplifier in parallel by operational amplifier A 1 and A2; resistance R 1 and R2 and operational amplifier A 3 formation common-mode signals extraction drive circuits that two similar resistance are arranged; take out common-mode signal to differential high pass filter (respectively by C1 and R3; C2 and R4) common port drive, can avoid the interference of the asymmetric common mode variation mould that causes that is difficult to avoid between C2 and the R4 being introduced owing to C1 and R3 effectively.∑-Δ pattern number converter is used for mimic bioelectrical signals is converted to high-resolution digital signal, microprocessor (CPU) has the digital spectrum compensation program, be used for the digital signal of ∑-Δ pattern number converter output is carried out frequency compensation, to eliminate this unevenness in passband of ∑-Δ pattern number converter.Driven-right-leg circuit by operational amplifier A 4, R5 and R6 and C3 constitute with the anti-phase driving public electrode of common-mode signal, can further suppress common-mode signal.∑ of the present invention-Δ pattern number converter and microprocessor are integrated on one piece of chip.
Because differential amplifier in parallel has infinitely-great common mode rejection ratio in theory when differential output, side circuit also has very high common mode rejection ratio, and adopting ∑-Δ pattern number converter also to have very high common mode rejection ratio with differential input, both constitute perfect cooperation like this.In order to suppress direct current and intrasonic interference such as polarizing voltage and baseline drift, between differential amplifier in parallel and ∑-Δ pattern number converter, add by C1 and R3, the high pass filter that C2 and R4 constitute, generally require them should have high matching precision, could guarantee the common mode rejection ratio performance of circuit, and resistance R 1 and R2 and operational amplifier A 3 formation common-mode signals extraction drive circuits can be very poor at their matching precisions, even their appearance value or resistance differ several times situation under can both guarantee very high common mode rejection ratio, reduced circuit to the requirement of components and parts with simplified technology.

Claims (4)

1, a kind of bioelectrical detection circuit, it is characterized in that, it comprises the electrode that is used to gather bioelectrical signals that connects successively by lead, has the input protection circuit of overvoltage protection and simple filter function, has differential amplifier in parallel, ∑-Δ pattern number converter and microprocessor CPU that common mode drives, is connected with driven-right-leg circuit between described electrode and the described differential amplifier in parallel; Described ∑-Δ pattern number converter is used for mimic bioelectrical signals is converted to high-resolution digital signal.
2, a kind of bioelectrical detection circuit according to claim 1, it is characterized in that, described driven-right-leg circuit is made of operational amplifier A 4, resistance R 5, R6 and capacitor C 3, be used for the anti-phase driving public electrode of the common-mode signal of described differential amplifier in parallel, with further inhibition common-mode signal.
3, a kind of bioelectrical detection circuit according to claim 1, it is characterized in that, described differential amplifier in parallel is made of operational amplifier A 1 and A2, the resistance R 1 of two similar resistance and R2 and operational amplifier A 3 constitute common-mode signal and extract drive circuit, and the output signal that common-mode signal is extracted drive circuit exports described driven-right-leg circuit to.
4, a kind of bioelectrical detection circuit according to claim 2, it is characterized in that, between described differential amplifier in parallel and described ∑-Δ pattern number converter, be connected with high pass filter, high pass filter is made up of capacitor C 1 and C2, resistance R 3 and R4, is used to suppress the interference of polarizing voltage and baseline drift; The output signal of common-mode signal extraction drive circuit exports the resistance R 3 of described high pass filter, the common port of R4 in the described differential amplifier in parallel.
CNB2004100727898A 2004-11-18 2004-11-18 Bioelectrical detection circuit Expired - Fee Related CN1299640C (en)

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Application Number Priority Date Filing Date Title
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CN1299640C true CN1299640C (en) 2007-02-14

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Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101449970B (en) * 2008-12-29 2013-01-16 天津大学 Bioelectric amplifier
CN101889863B (en) * 2009-05-21 2013-06-19 深圳市理邦精密仪器股份有限公司 High-performance direct current amplification device for acquiring biological electric signals
CN103142397A (en) * 2013-02-03 2013-06-12 常熟柏宇医疗电子有限公司 Electromagnetic adsorption sputum excretion system with diode amplifier
CN103070759A (en) * 2013-02-03 2013-05-01 常熟柏宇医疗电子有限公司 Electromagnetic adsorption sputum excretion system with overvoltage protection and filtering integration circuit
CN103070770A (en) * 2013-02-03 2013-05-01 常熟柏宇医疗电子有限公司 Electromagnetic adsorption sputum excretion system with power tube
CN110786848B (en) * 2019-10-22 2022-03-15 天津大学 Single-channel acquisition amplifier for multiple physiological parameter signals
CN112994650A (en) * 2021-02-23 2021-06-18 青岛鼎信通讯股份有限公司 Differential signal common mode noise suppression device for power distribution terminal communication module

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4156430A (en) * 1975-10-08 1979-05-29 Hoffmann-La Roche Inc. Instrumentation for pacemaker diagnostic analysis
US5055843A (en) * 1990-01-31 1991-10-08 Analog Devices, Inc. Sigma delta modulator with distributed prefiltering and feedback
US5092341A (en) * 1990-06-18 1992-03-03 Del Mar Avionics Surface ecg frequency analysis system and method based upon spectral turbulence estimation
CN2363654Y (en) * 1999-01-19 2000-02-16 华南理工大学 Heart function parameter tester
CN1291465A (en) * 2000-08-02 2001-04-18 天津市四通新技术开发公司 Domestic electrocardiographic oscilloscope
CN2530301Y (en) * 2001-03-09 2003-01-08 北京卡迪欧医疗设备有限责任公司 Analyser for electrocardiosignal

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4156430A (en) * 1975-10-08 1979-05-29 Hoffmann-La Roche Inc. Instrumentation for pacemaker diagnostic analysis
US5055843A (en) * 1990-01-31 1991-10-08 Analog Devices, Inc. Sigma delta modulator with distributed prefiltering and feedback
US5092341A (en) * 1990-06-18 1992-03-03 Del Mar Avionics Surface ecg frequency analysis system and method based upon spectral turbulence estimation
CN2363654Y (en) * 1999-01-19 2000-02-16 华南理工大学 Heart function parameter tester
CN1291465A (en) * 2000-08-02 2001-04-18 天津市四通新技术开发公司 Domestic electrocardiographic oscilloscope
CN2530301Y (en) * 2001-03-09 2003-01-08 北京卡迪欧医疗设备有限责任公司 Analyser for electrocardiosignal

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