CN1283262C - Dry scorpion venom powder and its preparation - Google Patents

Abstract

The present invention relates to dry scorpion venom powder and a preparing method thereof. Firstly, healthy scorpions with good quality are selected and then preheated at 25 to 35 DEG C, and before extraction, physiological saline is used for moistening. Secondly, the scorpions are arranged on venom extracting devices in order in an aseptic constant temperature room, electricity is supplied to make the scorpions discharge venom, and the venom is collected and then treated. Finally, post-treatment is carried out in an aseptic room, crystals in the shape of a needle cylinder are formed and then are tested, and after split charging in vacuum according to bottom/gram, the crystals are lyophilized. The dry scorpion venom powder is refrigerated at the constant temperature of-5 DEG C for spare use and can be stored for a long term. The present invention provides dry scorpion venom powder with the advantages of extraction of pure original venom, large extraction quantity and long-stem storage and also provides a method for preparing the dry scorpion venom powder.

Description

The preparation method of scorpion venom dry powder

Technical field: the preparation method that the present invention relates to a kind of scorpion venom dry powder.

Background technology: at present, scorpion venom is mainly used in biological preparation and the bio-pharmaceuticals, or carry out deep processing as raw material and batching etc., and obtain pharmaceutical formulation and clinical practice, especially effect is remarkable in the treatment difficult miscellaneous diseases, because being widely used of scorpion venom, consumption is big, is that the present scorpion venom extractive technique of China can't satisfy, in addition, the venom that extracts exists with liquid form mostly at present, can not long preservation.

Summary of the invention: in order to solve the problem of above-mentioned existence, the invention provides that the former poison of a kind of extraction is pure, extracted amount is big, and the preparation method of scorpion venom dry powder that can long preservation.

Concrete technical scheme is as follows: a kind of preparation method of scorpion venom dry powder, and it may further comprise the steps:

1. screening: screen healthy fine Scorpio, preheating under 25 ℃-35 ℃ condition is used the normal saline dewing before extracting;

2. extract: be extracted in that sterile constant-temperature is indoor to carry out, Scorpio be emitted on to carry in order to give electricity on the malicious equipment, make Scorpio discharge venom, handle after the collection.

3. post processing: post processing is carried out in sterilizing room, forms pin column crystallization body and tests, by lyophilizing after the packing of every bottle/gram vacuum;

4. cold preservation: it is standby to carry out constant temperature cold preservation under-5 ℃, can long preservation.

The present invention has the following advantages:

1, adopt the micro-electrical stimulation means under aseptic condition, make its toxin expelling, the poison amount is big, and former poison is pure.

2, can long preservation.

3, contain rich in amino acid, see following table for details:

Amino acid analysis
			Project	Unit	The result
Aspartic acid ASP	mg/100g	4649
			Threonine THR	mg/100g	1527
Serine SER	mg/100g	980
			Glutamic acid GLU	mg/100g	2045
Glycine GLY	mg/100g	1907
			Alanine ALA	mg/100g	1487
Cystine CYS	mg/100g	666
			Valine VAL	mg/100g	2374
Methionine MET	mg/100g	415
			Isoleucine ILE	mg/100g	890
Leucine LEU	mg/100g	1188
			Tyrosine TYR	Mg/100g	1740
Phenylalanine PHE	mg/100g	1047
			Lysine LYS	mg/100g	2960
Ammonia NH3	mg/100g	175
			Histidine HIS	mg/100g	511
Arginine ARG	mg/100g	1821
			Proline PRO	mg/100g	1230
Total amino acid content	mg/100g	27612

The specific embodiment:

Embodiment: a kind of scorpion venom dry powder and preparation method thereof, it may further comprise the steps:

1, screening: screen healthy fine Scorpio, preheating under 25 ℃-35 ℃ condition is used the normal saline dewing before extracting;

2, extract: be extracted in that sterile constant-temperature is indoor to carry out, Scorpio be emitted on to carry in order to give electricity on the malicious equipment, make Scorpio discharge venom, handle after the collection.

3, post processing: post processing is carried out in sterilizing room, forms pin column crystallization body and tests, by lyophilizing after the packing of every bottle/gram vacuum;

4, cold preservation: it is standby to carry out constant temperature cold preservation under-5 ℃, can long preservation.

Claims (1)

1, a kind of preparation method of scorpion venom dry powder is characterized in that it may further comprise the steps:

1. screening: screen healthy fine Scorpio, preheating under 25 ℃-35 ℃ condition is used the normal saline dewing before extracting;

2. extract: be extracted in that sterile constant-temperature is indoor to carry out, Scorpio be emitted on to carry in order to give electricity on the malicious equipment, make Scorpio discharge venom, handle after the collection;

3. post processing: post processing is carried out in sterilizing room, forms pin column crystallization body and tests, by lyophilizing after the packing of every bottle/gram vacuum;

4. cold preservation: it is standby to carry out constant temperature cold preservation under-5 ℃, can long preservation.