CN1254250C - Chinese medicine for treating eye diseases and its prepn process - Google Patents
Chinese medicine for treating eye diseases and its prepn process Download PDFInfo
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- CN1254250C CN1254250C CNB021029784A CN02102978A CN1254250C CN 1254250 C CN1254250 C CN 1254250C CN B021029784 A CNB021029784 A CN B021029784A CN 02102978 A CN02102978 A CN 02102978A CN 1254250 C CN1254250 C CN 1254250C
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Abstract
The present invention relates to a traditional Chinese medicine, particularly to a traditional Chinese medicine eye drop for treating eye diseases and a preparation method thereof. The traditional Chinese medicine is mainly prepared by making sesame oil, scorpions, centipedes and earthworms into drops by using special technology. Through clinical observation, the traditional Chinese medicine has a wide medicine treating range and can treat ceratonosus, iritis and secondary glaucoma. Through clinical practices for scores of years, the traditional Chinese has the effective rate of 100%, the cure rate of 96% and the rest rate of 4%. The present invention is prepared into drops by using traditional Chinese medicines by aiming at the characteristics of various intractable eye diseases, and the traditional Chinese medicine has optimum curative effect on treating various intractable diseases in ophthalmology department. After long term clinical observation, the traditional Chinese medicine has the advantages of no poison, no side effect and no generation of drug tolerance.
Description
Technical field
The present invention relates to Chinese medicine, particularly relate to a kind of Chinese medicine eye drop of oculopathy and preparation method of this medicine for the treatment of.
Background technology
According to the data introduction, keratopathy is one of our times three big diseases causing blindnesses, the whole world has millions of because of the blind patient of keratitis approximately, such as, the developed country U.S. has 50,000 people morbidity approximately, suffer from about 400,000 people of keratopathy, other developing country's prevalence is higher, and the annual impetus that growth is all arranged.The Western medicine preparation of the treatment keratopathy that present domestic extension is used, as: Runshu eye drops, the clean eye drop of profit etc., these Western medicine preparations, what antimicrbial power was strong can not antiviral, and the effective medicine of antiviral can not antibiotic or anaerobe resistant and other pathogenic microorganism.And when bacterial inflammation infects clinically, often when Abwehrkraft des Koepers is low, also join simultaneously and viral infection.Therefore the Western medicine eye drop does not possess dual nature.The keratitis patient often needs with the multiple eye drop of time point clinically.The patient that the typical case is serious, as: keratitis, corneal ulcer disease etc. often need to make good use of simultaneously several eye drops.In addition, along with human genome project's breakthrough and developing rapidly of high-tech product, introduce a kind of " Bei Fushu " eye drop according to interrelated data, this eye drop is to be considered to reasonable a kind of new drug at present, its treatment ocular injury curative effect is better, but the treatment for keratitis still needs to use ability effectively simultaneously with antibiotic and antiviral drugs, and its effective percentage is 57.1%.Still have a following several difficult problem that needs solution so be used for the treatment of the Western medicine preparation of keratitis and corneal ulcer at present:
Because the anatomical physiology characteristic of eyes, lachrymal gland are at the secretion tear that does not stop, eyes are in the suitable order motion that does not stop, with cleaning cornea and protection cornea.Even act on stronger eye drop, also can be diluted very soon and lessen the curative effect by tear.
The anatomical physiology characteristic of eyes has determined an eye drop to go into the conjunctiva bundle promptly to be inhaled fairly along lacrimal ductule tear bundle and drain after 10-12 minute by puncta, be difficult in and keep concentration medicine in the conjunctiva bundle for a long time.
Cornea requires to have the specific drugs that molecular weight is little, permeability is strong and have two dissolubilities of water solublity and fat melting coexistence.
The no blood vessel of cornea itself, the conveying of blood supply and nutrient substance will be leaned on blood capillary on every side, and tear and aqueous humor are supplied with.
At present keratopathy is one of our times three big diseases causing blindnesses, if it is millions of because of the keratopathy patient that loses one's sight recovers lost eyesight, by no means easy to only depend on corneal transplantation to solve.At first being the shortage of donor, secondly is the puzzlement of immunological rejection and the inevitable property of the many complication of postoperative.
Summary of the invention:
The object of the invention provides a kind of Chinese medicine drop with the multiple ophthalmology persistent ailment of treatment according to the defective that exists in the above prior art.
Another object of the present invention provides the preparation method of Chinese medicine drop.
The object of the invention realizes being made by following drug component (weight proportion):
(consumption is a weight portion) that medicine of the present invention is made by following component:
Oleum sesami 400～1000, Scorpio 2～36, Scolopendra 2～30, Pheretima 2～30.
The formula optimization weight proportion scope of preparation medicine of the present invention is:
Oleum sesami 500～1000, Scorpio 2～34, Scolopendra 2～28, Pheretima 2～25.
The optimum weight proportioning of preparation medicine of the present invention is:
Oleum sesami 500, Scorpio 30, Scolopendra 26, Pheretima 20.
Above-mentioned each component is made medicine production method of the present invention is:
Weight proportion by described medicine of the present invention, Scolopendra, Pheretima oven dry back grinding are put into Oleum sesami together with Scorpio, stir, under 20～23 ℃ of temperature environments, placed about 48 days, again under 15～18 ℃ of temperature environments, placed about 60 days, after filtration, high temperature sterilize, survey pH value 7～7.5, sterilization stores;
The present invention utilizes pure prepared from traditional Chinese medicines to form, and its compound traditional Chinese medical science medicament for the eyes preparation is theoretical.Because traditional Chinese medical science requirement in the process for preparation of medicament for the eyes drop must have the medicine mother, and Chinese medicine drop medicine mother's selection is crucial, and it is different from Western medicine collyrium solvent.The traditional Chinese medical science selects the medicine mother must promptly give shape, and Oleum sesami is the key medicine that cures mainly this disease simply, and it has effects such as antiviral, antibiotic, anticorrosion, pain relieving.Secondly it meets the physiological characteristics of cornea, has two dissolubilities: 1, be easy to see through corneal epithelium.2, have fat-solublely again, be easy to see through the cornea essential layer.From clinical observation, Drug therapy of the present invention is in extensive range, not only can treat keratopathy, can also treat iridocyclitis, secondary glaucoma.Through the clinical practice of decades, observe its effective percentage 100%, cure rate 96%, remaining is 4% years old.
At the characteristics of many intractable ophthalmics, the main sharp Chinese medicine configuration of the present invention forms drop, has obtained optimum curative effect in the multiple persistent ailment of treatment ophthalmology.Through long-term clinical observation, nontoxic, have no side effect, do not produce drug resistance.
The specific embodiment
Below by specific embodiment feature of the present invention and correlation technique feature are described in further detail:
The optimum weight proportioning of preparation medicine of the present invention is:
Oleum sesami 500, Scorpio 30, Scolopendra 26, Pheretima 20.
Above-mentioned each component is made medicine production method of the present invention is:
Weight proportion by described medicine of the present invention, Scolopendra 26g, Pheretima 20g oven dry back grinding is put into the 500ml Oleum sesami together with Scorpio 30g, stir, under 20～23 ℃ of temperature environments, placed about 48 days, again under 15～18 ℃ of temperature environments, placed about 60 days, after filtration, high temperature sterilize, survey pH value 7～7.5, sterilization gets final product;
Now typical clinical is reported as follows:
Example 1: anaerobe knot keratitis:
In x, woman, 72 years old, the Mongols, retired veteran cadre.Just precious in May, 1999, the main suit: right eye, secretions are extremely many, and half a year is surplus.History of present illness: the patient in November, 98 right eye red, secretions is extremely many, i.e. starting point chloromycetin, Margarita collyrium.Once locate just treasure in Shenzhen Futian hospital ophthalmology, city's hospital ophthalmology, central hospital's ophthalmology, Shenzhen Inst Eye Res etc., all be diagnosed as conjunctivitis.And do irrigation of lacrimal passage, unobstructed lacrimal passage.Do the conjunctiva antibacterial culturing, do not turn out antibacterial.Multiple antibiotics collyrium such as clean are relaxed, moistened to frequent always strong benzyloxy Flucloxacillin of point and profit.May 11 when asking expert's diagnosis and treatment in Beijing Tongren Hospital, still was diagnosed as conjunctivitis by way of Beijing, and medication is the same.May 14 went to a doctor to Inner Mongol Affiliated Hospital ophthalmology, was diagnosed as knot keratitis, some ACT collyrium and ciprofloxacin collyrium, unsatisfactory curative effect.So came to go to a doctor May 19, look into right eye: 0.6, left eye: 0.5, right eye is margo palpebrae and inside and outside this red swelling of the skin of order up and down, and the dense sexual secretion of a large amount of yellow green thickness is seen in the conjunctiva mixed congestion in the conjunctiva bundle.Abnormal flavour is arranged, and interior order portion can occur a yellow green thick secretions in per 2 minutes and pile up.The upper and lower lacrimal point in compressing tear bundle district does not have pyorrhea.Fluorescent dyeing is painted, the visible canescence inflammatory infiltration district of cornea of right eye central authorities.KP (-), room (-), crystal is the radial muddiness of inhomogeneous canescence.Optical fundus (-), left eye lenticular opacity than right eye for very.Seal is examined: 1, right eye knot keratitis.2, right eye blepharitis.3, bicrystal muddiness behind all eye dripping medicines before stopping, twice of conjunctiva bundle normal saline flushing, is put Chinese medicine drop of the present invention every day and is observed.5 days relief angle membrane-like of medication treatment are soaked into district's complete obiteration, and fluorescent dyeing is not painted.The conjunctival secretion color is light, and amount reduces gradually.May 28, unexpected secretions increased once more, especially as treatment at the beginning.Conjunctival congestion is obvious, cornea (-).So question closely medical history repeatedly: patient's readme was once wiped the examination eyes with saliva at that time because of there is the thick secretions adhesion on the eye limit on 25th.Recall in many ill half a year, the memory of wiping the examination eyes with saliva 5～6 times was once arranged, think that saliva is the cleanest.Consider to analyze: it is all invalid 1, to have used up all antibiotics collyrium in half a year.2, accept do not using under the situation of any other medicines in the treatment of Chinese medicine drop, cornea only depends on puts medicine once a day, i.e. recovery from illness in 5 days.Illustrate that the Chinese medicine drop is sure to this patient's curative effect.3, occurred the inducement that also useful repeatedly saliva is wiped the examination eyes suddenly in treatment, having illustrated not only needs strong medicine, also illustrate this patient by generally not susceptible antibacterial infect.4, once did the medical history that antibacterial is not turned out antibacterial in Shenzhen.So analyzing and diagnosing is an anaerobe knot keratitis.Further diagnosis was handled by anaerobe in back 30 days immediately: 1, twice usefulness metronidazole liquid flushing morning and afternoon every day conjunctiva bundle is twice.2, putting Chinese medicine drop of the present invention once a day observes.3, metronidazole 2#3 time/day oral, symptom obviously alleviates two days later, still changes into putting the Chinese medicine drop once a day and observing, treated altogether 50 days, the drug withdrawal of thoroughly fully recovering, follow-up study 6 months, not repeatedly.
Example 2: herpes simplex keratitis
Patient Zhu xx, the woman, 45 years old, the workman went to a doctor the main suit on 9th in December in 2000: year surplus the eyes erythralgia ten.History of present illness: right eye is red suddenly from 87 years, pain promptly is diagnosed as viral keratitis, treats with keratitis always.Nearly 2 years eyes are alternately red repeatedly, bitterly, through various treatments, unsatisfactory curative effect, frequently outbreak repeatedly recently.The general chance when flu, fatigue, menstrual period and oil smoke stimulate recurred.So come to go to a doctor, look into right eye: 0.9, left eye 0.8, cornea is inflammatory infiltration edema KP (-) around 12～5 visible semiarc shape cornea canescence holostrome muddinesses in position in the mixed congestion of fluorescence staining left eye bulbar conjunctiva, limbus of corneae, focus, the room dodges (-), PLR spirit.9～5 muddy districts of the irregular lamellar of the visible canescence in position in the edge of cornea of right eye top.Surrounding tissue infiltration edema is obvious.Bicrystal cortex is seen canescence point-like muddiness, and vitreous body is seen cotton-shaped mixing, and seal is examined: 1, two herpes simplex keratitises.2, lenticular opacity ou.3, left vitreous opacity is disposed, 1, stop using before all medicines; 2, eyes twice Chinese medicine drop of the present invention every day observed; December further consultation on the 10th: conscious some medicine right eye mill pain symptom obviously alleviates, and left eye mill pain increases the weight of.Look into the left eye bulbar conjunctiva with congested, limbus of corneae place focus is thin out, and infiltration district, 5 positions expanded range is soaked into and deepened, and all the other limbus of corneae place focuses are thin out.The right eye focus does not have obvious change, disposes.Eyes are still ditto put Chinese medicine of the present invention and are observed.From twice Chinese medicine of the present invention December in 2000 in August 9 days～calendar year 2001 this every day in stage,, just alleviate gradually though the old complaint kitchen range, still has new focus and constantly occurs when meeting flu and other inducement in absorption, thin out gradually.Old focus is absorbing thin outly gradually after August, does not occur new focus again; Change and put Chinese medicine of the present invention once a day; This shows that the self-resistance of keratitis and body has certain relation, thus since February 20 to 1 of patient's intramuscular injection gamma globulin, append 1 behind the two weeks.Confirmed a theory through clinical observation once more, from producing antibody after the resistance enhancing at eye needs 70 days; So the patient of every trouble keratopathy of a specified duration also will strengthen patient's self resistance except with this strong continual while of Chinese medicine drop, though otherwise old focus can cure, but new focus may appear at any time.This patient in November 20 fluorescence staining not painted, do not had any symptom, various inducements such as cold and high fever all do not have any discomfort to eyes.But on cornea, still have 3 lamellar speckles.According to clinical observation, Chinese medicine drop of the present invention can remove speckle, so continue some Chinese medicine drop of the present invention.In further consultation on January 20 in 2002, two corneas were as excellent as before, and any ill vestige is stayed at the end, the drug withdrawal of thoroughly fully recovering.Example 3: herpes simplex keratitis corneal ulcer:
Patient king xx, man, 30 years old, Han nationality, teacher.The main suit:, right eye is red, two more than ten years of pain, history of present illness: the patient is during from 9 years old, and right eye is red, bitterly, goes to a doctor at Inner Mongol hospital ophthalmology, Affiliated Hospital's ophthalmology and city's hospital ophthalmology always, all is diagnosed as viral keratitis.And treat with keratitis always.The various collyrium of partial points, subconjunctival injection, the systemic vein drop, oral Chinese medicine decoction and local acupuncture etc., curative effect is all not good, and the state of an illness increases the weight of gradually, so come to go to a doctor.On inspection, grow normally the nutrition extreme difference, have a delicate constitution, spirit is fragile, 35 kilograms of body weight, height 165cm, right vision light sensation at the moment, left vision 0.2, the mixed congestion of right eye bulbar conjunctiva ++ ++, fluorescence staining, large-area colouring, cornea has 8mm approximately, large tracts of land virus is invaded the district, and only visible edge of cornea has 1mm normal structure still approximately.The funnel-form large tracts of land ulcer surface of the visible about 4 * 5mm of cornea central authorities of pathological changes.The bottom of funnel is profound, the cornea rear wall as thin as a wafer, the ulcer central authorities of funnel-like have filled glistening sand and pitch-black foreign bodies such as cinder.Substrate is too thin, (can't take out foreign body) large tracts of land ulcer surface tiltedly in the below connect little slightly shallow about a 2 * 2cm of ulcer surface, cornea edema extremely around the ulcer surface is organized crisply, surface irregularity, inflammatory infiltration are very serious.Eye inner tissue peeps to go into.Left eye is looked far unclear, wears 375 degree glasses for the myopia.Seal is examined: 1, right eye herpes simplex keratitis.2, close companion's large tracts of land deep layer ulcer.3, may bore a hole at any time, dispose.All eye dripping medicines before stopping.Right eye point medicine Chinese medicine of the present invention drop is observed.Simple eye aseptic wrapping.Further consultation on October 30: no any discomfort sense behind the right eye point medicine, pain is more preceding obviously to be alleviated, on inspection: the mixed congestion of right eye bulbar conjunctiva, foreign bodies such as sand in the cornea central authorities large tracts of land ulcer surface depression and cinder all disappear, funnel shoals, and the reparation of ulcer surface lower edge shoals, and is slope (when foreign body may move along order at any time, brushed out ulcer surface), below aphtha face reparation shoals.Right eye is still ditto put Chinese medicine drop of the present invention and is observed.Further consultation on November 1: readme right eye mill pain obviously alleviates.On inspection: the same mixed congestion of right eye bulbar conjunctiva, corneal infiltration district edema obviously alleviates, and the more preceding reparation of cornea central authorities' ulcer surface shoals.Interior below aphtha face is repaired flat substantially.1, right eye is still put the observation of Chinese medicine drop.2, consider that the patient is ill too of a specified duration, body lower for the resistance, thus 2 of intramuscular injection placenta interstitial fluids, 1 time/day, but because of the patient has a delicate constitution, collapse during intramuscular injection, so drug withdrawal.The patient during receiving treatment from November heavy cold hyperpyrexia on the 3rd first quarter moon surplus.Use up the whole bag of tricks treatment.Corneal ulcer the first time occurs repeatedly to April 8 calendar year 2001, has successively occurred three times altogether repeatedly.New ulcer appears when running into inducements such as overtired and excess eye-using and, and, append 1 behind the first quarter moon 1 of intramuscular injection gamma globulin by the end of December.March and for it searches out Medulla Bovis seu Bubali fully nutrient 3 boxes, take after mixing it with water 2 bags of every days, building up resistance, and make its benefit beef or mutton soup, eat seafoods such as various high protein materials and fish, shrimp.After June calendar year 2001, the whole body resistance obviously improves, and the eye subjective symptoms disappears, and identifies oneself to fully recover.JIUYUE further consultation on the 15th: right vision index/1 meter, the right eye fluorescence staining is not painted, and bulbar conjunctiva does not have hyperemia, and cornea does not have edema and inflammatory infiltration, and edge of cornea portion focal zone is transparent, can peep tissues such as iris, the only visible greyish white mottle of cornea central authorities' focal zone.Further consultation on November 22: conscious eyes have uncomfortable sensation when looking thing, the right eye haplopia does not have any discomfort, identify oneself to cure completely, mood and good, right eye index/3 meter on inspection, left eye 0.2, the right eye bulbar conjunctiva does not have hyperemia, the complete obiteration of corneal infiltration edema, the cornea focus is repaired fully, is greyish white mottle nebula after the most outmoded the darkest ulcer reparation, and all the other positions are light greyish white inhomogeneous muddy district, may be seen indistinctly bright zone, anterior chamber, iris pupil is high-visible, and the optical fundus is normal.Right abtorsion-10 degree, left eye is disposed.Still continue some Chinese medicine drop of the present invention so that speckle is thoroughly eliminated.By nearly 1 year treatment, the healing of corneal inflammation has had a new understanding, the keratitis recovery from illness of past clinical diagnosis, in fact just the state of an illness temporarily is under control, and symptom has obtained alleviation, and practice confirms, the recovery from illness of real clinical diagnosis, be not only the not painted of fluorescence staining, and should be the complete obiteration of subjective symptoms, can not recur under any inducement.The complete obiteration of clinical examination nebula, as excellent as before, when observing no any change, long-time medication can diagnose the keratitis recovery from illness as needing for the speckle nebula, just can not occur repeatedly at this moment.
Example 4: secondary glaucoma ou
The patient, Si Qinbilige, the man, 35 years old, the Mongols, go to a doctor the main suit July 30 calendar year 2001: red, the distending pain of right eye, companion's headache, blurring of vision is surplus January.History of present illness: left eye is accompanied visual deterioration in May, 91 because of red, pain, promptly at Xilinhot City hospital row left eye operation for glaucoma, Postoperative visual acuity 0.2, still often red, bitterly, the eyeball distending pain, it is all high once arrive Inner Mongol hospital ophthalmology survey intraocular pressure several times.Make its clothes intraocular pressure lowering medicine keep.Before one month, right eye is red, pain is accompanied headache, eyeball distending pain.Blurring of vision, and oral ocular hypotensive agents thing, put that vision still obviously descends behind the various collyrium, symptom increases the weight of day by day, so come to go to a doctor, on inspection: the right eye index/at the moment, left eye light sensation/, survey intraocular pressure ou at the moment, 5.5/2=28.97mm Hg, the right eye bulbar conjunctiva is chronic mixed congestion, and the anterior chamber is shallow, the about 1/3ck of peripheral anterior chamber.The room sudden strain of a muscle+, iris texture is unclear, tissue looseness, there is the adhesion fully of needle point size only visible 10 positions of pupil neck, and all the other are all posterior synechiaes everywhere.Crystal is prenex to be hidden by a large amount of brown free pigments and fibrous exudation canescence film sample thing.Whole iris is Peng Long forward, and the optical fundus is peeped to be gone into.Seal is examined: 1, two secondary glaucomas.2, old iridocyclitis ou.3, two aftercataracts are disposed.Stop acetazolamide 250mgFid p.o.All eye dripping medicines before stopping.Eyes qd every day point Chinese medicine drop of the present invention is observed.Further consultation on July 31, the main suit: eyes distending pain and the complete obiteration of headache symptom, eyes are red before to be alleviated.On inspection: the right eye mixed congestion+, the anterior chamber is still shallow, the about 1/2ck of peripheral anterior chamber, and pupillary margin luminous reflectance motion in 10 positions of right eye is obvious, the room sudden strain of a muscle+, all the other are roughly the same.Left eye is roughly the same, disposes.Eyes are still ditto put the Chinese medicine drop and are observed.Further consultation on August 4: the eyes treatment is after 5 days, and the main suit: conscious eyes do not have any discomfort sense, and eyes are comfortable behind the some Chinese medicine drop of the present invention, and it is clear than before that right eye is looked thing.Vision right exponent/rice, the left eye light sensation/at the moment, eyes are pressed 5.5/5=17.30mmHg on inspection: the right eye bulbar conjunctiva is slightly congested, and cornea is clear, and iris texture is still clear, tissue looseness, smooth.Pupil is adhesion place enlarged areas 10-11 point position not.Visible needle point size place, other 2 positions pupillary margin has the movable sign of luminous reflectance.Prenex free pigment of crystal and fiber ooze out film and obviously absorb.Fang Qianqing, the room dodges and disappears the more preceding raising of vision.Left eye does not have hyperemia, and cornea is clear, and the anterior chamber obviously deepens.Iris is smooth, no Peng Long.12 position iris undercut mouths are clear, are the about 1 * 2mm of irregular vertical bar shape, pile up free pigment between mouthful and obviously absorb.It is evenly muddy that crystal is porcelain white, disposes.1, eyes are still put Chinese medicine drop observation of the present invention.2, periodic review.December further consultation on the 1st: eyes do not have any discomfort sense, and it is clear that right eye is looked thing, can see TV clearly.Point of interruption medicine voluntarily before more than 20 day.Have an eyesight test 0.5, left sensitization/at the moment, cornea of right eye is still clear, and (-), the room dodges (-), and anterior chamber's depth is normal, and iris is smooth, pupil 10-11.30 point position luminous reflectance sensitivity, 2 position pupillary margins have slight luminous reflectance motion sign.Still popularity posterior synechiae of remainder.The prenex surface fiber of crystal oozes out film and free pigment absorbs fully.Crystal is still transparent.Left eye does not have hyperemia, and anterior chamber's depth is normal, and iris is smooth, pupil extensive adhesion locking.The prenex free pigment of crystal absorbs.Crystal is uniformity porcelain white.12 irregular iris otch in position are met personally the small-amount free pigment, dispose.1, eyes are still put Chinese medicine drop observation of the present invention; 2, periodic review; 3, note avoiding long-time, in order to avoid excessively cause the iridocyclitis recurrence with eye with eye.
Claims (3)
1, a kind of Chinese medicine for the treatment of oculopathy, it is characterized in that it is made by described method by the following weight proportion raw material: get Oleum sesami 400～1000, Scorpio 2～36, Scolopendra 2～30, Pheretima 2～30, Scolopendra, Pheretima oven dry back are ground with golden scorpion 30g and put into Oleum sesami simultaneously, stir, under 20～23 ℃ of temperature environments, placed 48 days, under 15～18 ℃ of temperature environments, placed 60 days again, after filtration, high temperature sterilize, surveying pH value is 7～7.5, gets final product.
2, Chinese medicine according to claim 1 is characterized in that the weight proportion of each raw material is: Oleum sesami 500～1000, Scorpio 2～34, Scolopendra 2～28, Pheretima 2～25.
3, Chinese medicine according to claim 1 is characterized in that the weight proportion of each raw material is: Oleum sesami 500, Scorpio 30, Scolopendra 26, Pheretima 20.
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| CNB021029784A CN1254250C (en) | 2002-02-08 | 2002-02-08 | Chinese medicine for treating eye diseases and its prepn process |
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| CNB021029784A CN1254250C (en) | 2002-02-08 | 2002-02-08 | Chinese medicine for treating eye diseases and its prepn process |
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| CN1254250C true CN1254250C (en) | 2006-05-03 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101675939B (en) * | 2008-09-16 | 2012-04-04 | 谭振花 | Traditional Chinese medicine eye drops for treating keratitis |
| CN103768113A (en) * | 2012-10-17 | 2014-05-07 | 方山玉 | Method for preparing traditional Chinese medicine eye drops for treating cataract |
| CN104491225A (en) * | 2014-12-19 | 2015-04-08 | 公慧敏 | Traditional Chinese medicine eye drop for treating keratoconjunctivitis sicca and preparation method thereof |
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