CN1240712C - Method of preparing tyrosine-serine-leucine tripeptide - Google Patents
Method of preparing tyrosine-serine-leucine tripeptide Download PDFInfo
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- CN1240712C CN1240712C CN 03117845 CN03117845A CN1240712C CN 1240712 C CN1240712 C CN 1240712C CN 03117845 CN03117845 CN 03117845 CN 03117845 A CN03117845 A CN 03117845A CN 1240712 C CN1240712 C CN 1240712C
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- 238000000034 method Methods 0.000 title claims abstract description 27
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- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 10
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims abstract description 8
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- NPZTUJOABDZTLV-UHFFFAOYSA-N hydroxybenzotriazole Substances O=C1C=CC=C2NNN=C12 NPZTUJOABDZTLV-UHFFFAOYSA-N 0.000 claims description 12
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
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- FHOAKXBXYSJBGX-YFKPBYRVSA-N (2s)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid Chemical compound CC(C)(C)OC(=O)N[C@@H](CO)C(O)=O FHOAKXBXYSJBGX-YFKPBYRVSA-N 0.000 claims description 6
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- 241000196324 Embryophyta Species 0.000 description 12
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 12
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- Peptides Or Proteins (AREA)
Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 03117845 CN1240712C (en) | 2003-05-09 | 2003-05-09 | Method of preparing tyrosine-serine-leucine tripeptide |
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CN 03117845 CN1240712C (en) | 2003-05-09 | 2003-05-09 | Method of preparing tyrosine-serine-leucine tripeptide |
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CN1513871A CN1513871A (en) | 2004-07-21 |
CN1240712C true CN1240712C (en) | 2006-02-08 |
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CN 03117845 Expired - Fee Related CN1240712C (en) | 2003-05-09 | 2003-05-09 | Method of preparing tyrosine-serine-leucine tripeptide |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2011524340A (en) * | 2008-05-21 | 2011-09-01 | ニュー・ワールド・ラボラトリーズ・インコーポレイテッド | Selective caspase inhibitors and uses thereof |
US9045524B2 (en) | 2009-05-21 | 2015-06-02 | Novagenesis Foundation | Selective caspase inhibitors and uses thereof |
CN101906136B (en) * | 2009-06-02 | 2012-12-12 | 首都医科大学 | Amino acid-(3,4-dyhydroxy-Phe)-Ser-Leu false peptide, and synthesizing method and application thereof |
ES2665301T3 (en) | 2011-04-15 | 2018-04-25 | Genesis Technologies Limited | Selective cysteine prorease inhibitors and their uses |
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Owner name: KANGZHE PHARMACEUTICAL INDUSTRY CO., LTD., SHENZH Free format text: FORMER OWNER: YITAI MEDICINE RESEARCH (SHENZHEN) CO., LTD. Effective date: 20040430 |
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C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20040430 Address after: Guangdong Shenzhen Futian District Bagua three road deep medicine building on the east side of the two building Applicant after: Kangzhe Pharmaceutical Industry Co., Ltd., Shenzhen Address before: Room 301-304, deep medicine building, Bagua Road, Shenzhen, Guangdong three, China Applicant before: Yitai Medicine Research (Shenzhen) Co., Ltd. |
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060208 Termination date: 20210509 |
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CF01 | Termination of patent right due to non-payment of annual fee |