CN1209150C - Shizi oil - Google Patents
Shizi oil Download PDFInfo
- Publication number
- CN1209150C CN1209150C CN 03119195 CN03119195A CN1209150C CN 1209150 C CN1209150 C CN 1209150C CN 03119195 CN03119195 CN 03119195 CN 03119195 A CN03119195 A CN 03119195A CN 1209150 C CN1209150 C CN 1209150C
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- CN
- China
- Prior art keywords
- oil
- oleum
- medicine
- pharmaceutical preparation
- shizi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000003814 drug Substances 0.000 claims abstract description 30
- 239000003921 oil Substances 0.000 claims abstract description 30
- 235000019198 oils Nutrition 0.000 claims abstract description 30
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 11
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 11
- 208000003251 Pruritus Diseases 0.000 claims abstract description 7
- 241000255925 Diptera Species 0.000 claims abstract description 5
- 210000004369 blood Anatomy 0.000 claims abstract description 5
- 239000008280 blood Substances 0.000 claims abstract description 5
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims abstract description 4
- 235000019477 peppermint oil Nutrition 0.000 claims abstract description 4
- 229940079593 drug Drugs 0.000 claims description 8
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims description 5
- 229940025250 camphora Drugs 0.000 claims description 5
- 239000010238 camphora Substances 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- 206010007247 Carbuncle Diseases 0.000 claims description 4
- 230000000202 analgesic effect Effects 0.000 claims description 4
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 3
- 210000000629 knee joint Anatomy 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 claims description 2
- 229940040145 liniment Drugs 0.000 claims description 2
- 239000000865 liniment Substances 0.000 claims description 2
- 208000026435 phlegm Diseases 0.000 claims description 2
- 239000006187 pill Substances 0.000 claims description 2
- 239000002574 poison Substances 0.000 claims description 2
- 231100000614 poison Toxicity 0.000 claims description 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 8
- 208000002193 Pain Diseases 0.000 abstract description 17
- 230000008961 swelling Effects 0.000 abstract description 7
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 abstract 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 2
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 2
- 229940116229 borneol Drugs 0.000 abstract 2
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 2
- 229940041616 menthol Drugs 0.000 abstract 2
- GRWFGVWFFZKLTI-UHFFFAOYSA-N α-pinene Chemical compound CC1=CCC2C(C)(C)C1C2 GRWFGVWFFZKLTI-UHFFFAOYSA-N 0.000 abstract 2
- GRWFGVWFFZKLTI-IUCAKERBSA-N 1S,5S-(-)-alpha-Pinene Natural products CC1=CC[C@@H]2C(C)(C)[C@H]1C2 GRWFGVWFFZKLTI-IUCAKERBSA-N 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 241000779819 Syncarpia glomulifera Species 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- MVNCAPSFBDBCGF-UHFFFAOYSA-N alpha-pinene Natural products CC1=CCC23C1CC2C3(C)C MVNCAPSFBDBCGF-UHFFFAOYSA-N 0.000 abstract 1
- 239000010495 camellia oil Substances 0.000 abstract 1
- 229960000411 camphor oil Drugs 0.000 abstract 1
- 239000010624 camphor oil Substances 0.000 abstract 1
- 239000010634 clove oil Substances 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 239000001739 pinus spp. Substances 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 229940036248 turpentine Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 description 4
- 206010023232 Joint swelling Diseases 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 206010003399 Arthropod bite Diseases 0.000 description 2
- 208000006877 Insect Bites and Stings Diseases 0.000 description 2
- 208000025747 Rheumatic disease Diseases 0.000 description 2
- 208000026137 Soft tissue injury Diseases 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000000552 rheumatic effect Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000012850 discrimination method Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 238000002558 medical inspection Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to Shizi oil. The present invention is medicine which relieves inflammation, alleviates pain, expels wind and removes blood stasis and is used for the toxin and the injury of mosquitoes, itchy skin, windphlegm patellar tumefaction, pimple painful swelling and innominate painful swelling. The medicine of the present invention is composed of peppermint oil, spirit of turpentine, camphor oil, borneol, clove oil and menthol. The menthol and the borneol of the eight kinds of medicine are dissolved in each medicine oil of a prescription, and 1000 ml of tea oil is added in the medicine oil so as to be evenly mixed and filtered; thus, the Shizi oil can be obtained. The present invention contains alpha-pinene (C10H16) which is equal to or larger than 24.5.0%(g/g).
Description
The present invention relates to a kind of anti-inflammatory analgetic, the blood stasis removing function of dispeling the wind is used for the mosquito poison and hinders, skin pruritus, and wind-phlegm crane knee joint, minor carbuncle swells and ache, the medicine of nameless gall.The invention still further relates to the preparation method of this medicine, the invention reside in provides a kind of scientific matching of the best method, has formulated this drug quality discrimination method.
Another object of the present invention has provided the preparation method of Shizi oil.
To achieve these goals, the present invention takes following technical scheme:
Medicine of the present invention is to be made by following component:
Prescription: Oleum menthae 40ml～60ml Oleum Terebinthinae 300ml～400ml
Oleum Camphora 150ml～250ml Borneolum Syntheticum 40g～60g
Oleum Caryophylli 80ml～120ml Mentholum 5g～15g
The best proportioning of medicine of the present invention is:
Prescription: Peppermint Oil 50 ml Oleum Terebinthinae 350ml
Oleum Camphora 190 Borneolum Syntheticum 50g
Oleum Caryophylli 100ml Mentholum 10g
Technical scheme of the present invention is to grope according to clinical experiment for many years, has found a kind of matching method of treatment effect the best, and has formulated the authentication method of this medicine.
More than eight flavors, get Mentholum, Borneolum Syntheticum and be dissolved in each medicine oil of prescription, add Oleum Camelliae again to 1000ml, mixing filters, promptly.This product contains australene (C
10H
16) must not be less than one of method that 24.5.0% (g/g) makes medicine of the present invention with above-mentioned each component and be:
Prescription: Peppermint Oil 50 ml Oleum Terebinthinae 350ml
Oleum Camphora 190 Borneolum Syntheticum 50g
Oleum Caryophylli 100ml Mentholum 10g
1, branch is got the medicine oil of respectively distinguishing the flavor of, and is qualified according to the legal medicine standard test.
2, above eight flavors are got Mentholum, Borneolum Syntheticum and are dissolved in each medicine oil of prescription, add Oleum Camelliae again to 1000ml, and mixing filters, promptly.
Embodiment 2:
The proportioning raw material according to 2000 editions two-shift system agent of Chinese Pharmacopoeia standard, is made liniment, externally used paste, medicated wine, oil preparation, drop pill, smears as stated above.
Shizi oil is a kind of blood stasis removing that dispels the wind that Hong Kong and south east asia are commonly used, the medicine of anti-inflammatory analgetic, and Mi Shen is liked by the patient for many years.From in JIUYUE, 2000 to 2002 year November, the inventor entrusts Zhuhai City institute of traditional Chinese medicine respectively, Guangzhou institute of traditional Chinese medicine, Shenzhen institute of traditional Chinese medicine, how tame clinical units such as Shantou institute of traditional Chinese medicine carry out clinical observation on the therapeutic effect to Shizi oil, and selected case all is the loyal person that is in hospital, and suffer from minor carbuncle through medical inspection respectively with diagnosis and swell and ache, skin pruritus, the caused red and swollen heat pain symptom of mosquito bite and insect bite; Wherein suffer from rheumatic ostalgia patient 256 people, suffer from bones and muscles pain patient 245 people, loyal minor carbuncle swells and ache patient 242 people, suffers from skin pruritus patient 182 people, suffers from mosquito caused red and swollen heat pain patient 150 people that bite.
Table 1 Shizi oil clinical observation on the therapeutic effect catalog
By the Shizi oil clinical case is analyzed, prove that Shizi oil is at treatment rheumatic ostalgia, nameless gall, skin pruritus, symptom determined curative effects such as the caused red and swollen heat pain of mosquito bite and insect bite.
Model case:
1, patient Lee * *, the man, 57 years old, March calendar year 2001, Guangzhou City Traditional Chinese Medicine Hospital's orthopaedics was gone to a doctor, foot has been turned round during the readme walking along the street, existing ankle swelling pain, and through X-ray examination, the end sees that bone is unusual, preliminary card is disconnected to be soft tissue injury, and through using grand sharp board Shizi oil 3 days, pain and swelling obviously alleviates.Suggestion continues to use Shizi oil about one week, has a rest three days.
2, patient Lee * *, the man, 57 years old, August calendar year 2001, Guangzhou City Traditional Chinese Medicine Hospital's orthopaedics was gone to a doctor, and the readme cervical vertebra ache through X-ray examination, sees that vertebra length has bony spur, and preliminary card is disconnected to be cervical vertebra bony spur, and through using grand sharp board Shizi oil 5 days, pain obviously alleviates.Suggestion continues to use Shizi oil.
3, patient woods * *, the man, 64 years old, Guangzhou City Traditional Chinese Medicine Hospital's orthopaedics prescription on individual diagnosis in January calendar year 2001 orthopaedics was gone to a doctor, pain around the readme lumbar vertebra reaches through X-ray examination, is seen the lumbar intervertebral disc dystopy, preliminary card is disconnected asks that for lumbar vertebra dish is outstanding, and through using grand sharp board Shizi oil 5 days, pain obviously alleviates.Suggestion continues to use Shizi oil.
4, the patient opens * *, the man, and 46 years old, Shantou City in April calendar year 2001 hospital of traditional Chinese hospital's orthopaedics was gone to a doctor, and readme ankle swelling pain through X-ray examination, does not see that bone is unusual, and preliminary card is disconnected does not fully recover for soft tissue injury,
5, patient Jiang * *, the woman, 28 years old, in JIUYUE, 2002 came Guangzhou City Traditional Chinese Medicine Hospital's department of dermatologry to go to a doctor, and go out weekend, and bitten by mosquito in many places such as extremity and face, swelling pain, skin pruritus, through using grand sharp board Shizi oil 3 days, pain and swelling obviously alleviates.Suggestion continues to use Shizi oil about 3 days.
6, grandson patient * *, the woman, 45 years old, Zhuhai City's in March, 2002 hospital of traditional Chinese hospital's surgery was gone to a doctor, 1.8 centimetres of left and right sides furuncles of the long diameter of cervical region, swelling pain, through using grand sharp board Shizi oil 3 days, pain and swelling obviously alleviates and diminishes.Suggestion continues to use Shizi oil about 3 days.
7, the patient is permitted * *, the man, 61 years old, went to a doctor in the hospital of traditional Chinese hospital, Zhuhai City's in October, 2000, and readme knee joint swelling pain for many years, overcast and rainy increasing the weight of, accelerate the rheumatoid factor positive, the arthralgia that preliminary card breaks and causes for rheumatism through the examination erythrocyte sedimentation rate, through using grand sharp board Shizi oil three days, pain obviously alleviates.The grand sharp board Shizi oil of suggestion life-time service.
Claims (6)
1, a kind of energy anti-inflammatory analgetic, the pharmaceutical preparation of the blood stasis removing that dispels the wind is characterized in that it is the pharmaceutical preparation of making according to following prescription with following raw material:
Oleum menthae 40ml～60ml Oleum Terebinthinae 300ml～400ml
Oleum Camphora 150ml～250ml Borneolum Syntheticum 40g～60g
Oleum Caryophylli 80ml～120ml Mentholum 5g～15g
Above Six-element is got Mentholum, Borneolum Syntheticum and is dissolved in each medicine oil of prescription, adds Oleum Camelliae again to 1000ml, and mixing filters, promptly.
2, pharmaceutical preparation according to claim 1, wherein the optimum formula proportioning of each raw material is:
Peppermint Oil 50 ml Oleum Terebinthinae 350ml
Oleum Camphora 190ml Borneolum Syntheticum 50g
Oleum Caryophylli 100ml Mentholum 10g.
3, pharmaceutical preparation according to claim 1 and 2 is characterized in that said medicine is: liniment, externally used paste, medicated wine, oil preparation, drop pill, smears.
4, pharmaceutical preparation according to claim 1 and 2 is characterized in that the preparation method of said pharmaceutical preparation is: above Six-element, and get Mentholum, Borneolum Syntheticum and be dissolved in each medicine oil of prescription, add Oleum Camelliae again to 1000ml, mixing filters, that is,
This product contains α one pinene C
10H
16Must not be less than 24.5% by mass.
5, pharmaceutical preparation according to claim 1 and 2 is characterized in that said pharmaceutical preparation has anti-inflammatory analgetic, the effect of the blood stasis removing that dispels the wind, and is used for that mosquito poison wound, skin pruritus, wind-phlegm crane knee joint, minor carbuncle swell and ache, nameless gall.
6, according to claim 1 or 2 above pharmaceutical preparatioies, crude drug wherein should be country legal drug standard or corresponding medicinal standard.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03119195 CN1209150C (en) | 2003-03-18 | 2003-03-18 | Shizi oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03119195 CN1209150C (en) | 2003-03-18 | 2003-03-18 | Shizi oil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1443564A CN1443564A (en) | 2003-09-24 |
| CN1209150C true CN1209150C (en) | 2005-07-06 |
Family
ID=27815008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03119195 Expired - Fee Related CN1209150C (en) | 2003-03-18 | 2003-03-18 | Shizi oil |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1209150C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103099892B (en) * | 2013-01-09 | 2015-04-29 | 张大雷 | Plaster for treating arthralgia and myalgia |
| CN104623601B (en) * | 2015-02-04 | 2018-02-13 | 北京全净通一科技有限公司 | A kind of exterior-applied antalgic finish and preparation method |
| CN104800722B (en) * | 2015-04-16 | 2018-08-28 | 中国热带农业科学院热带生物技术研究所 | A kind of pharmaceutical composition, preparation and preparation method thereof |
| CN108853295A (en) * | 2018-07-27 | 2018-11-23 | 龚海辉 | This external prescription of a kind of network honeysuckle stem and preparation method thereof |
| CN108653447A (en) * | 2018-08-16 | 2018-10-16 | 江西省仁聚堂药业有限公司 | A kind of preparation method of Chinese herbal formula |
| CN113082118A (en) * | 2021-04-14 | 2021-07-09 | 郭佳嵘 | Tea oil mint paste and preparation method thereof |
-
2003
- 2003-03-18 CN CN 03119195 patent/CN1209150C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1443564A (en) | 2003-09-24 |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20090116 Address after: Jinding Industrial Park, Jinfeng West Road, Zhuhai, Guangdong Patentee after: Zhuhai Hongli Pharmaceutical Co., Ltd. Address before: Hongli pharmaceutical factory, Jinfeng West Road, Jinding Industrial Zone, Tang Town, Zhuhai, Guangdong Patentee before: Peng Shaoming |
|
| ASS | Succession or assignment of patent right |
Owner name: ZHUHAI HONGLI PHARMACY CO., LTD. Free format text: FORMER OWNER: PENG SHAOMING Effective date: 20090116 |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20050706 Termination date: 20180318 |
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| CF01 | Termination of patent right due to non-payment of annual fee |