CN1203077A - Method for getting roborant and anti-senile of man and buck - Google Patents
Method for getting roborant and anti-senile of man and buck Download PDFInfo
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- CN1203077A CN1203077A CN 98111396 CN98111396A CN1203077A CN 1203077 A CN1203077 A CN 1203077A CN 98111396 CN98111396 CN 98111396 CN 98111396 A CN98111396 A CN 98111396A CN 1203077 A CN1203077 A CN 1203077A
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- total isoflavone
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Abstract
An anti-sanility method for making male animal or man robuster features that total isoflavone thas is not hormonal medicine is orally taken or injected by 0.3-100 mg every day for one kg of body weight for 1-3 months, resulting in increasing body weight by 8-20%, muscle weight by 5-10%, testis weight by 10-30%, serum testosterone content by 20-50%, growth hormone content by 10-20% and activity of SOD, and decreasing the oxidation lipoid in serum and liver by 45% and 20%. Its advantages are no specificity, low cost and wide adaptable range.
Description
The invention belongs to the strong and defying age technology of promotion humans and animals, belong to the using method of non-hormone medicine, be exclusively used in male and buck, strengthen male characteristic, make the weightening finish of genitals and muscle, SOD is active to raise, lipid peroxide decline.
Slow down aging, health invigorating are the inevitable requirements that the modern adapts to the modern life of high strength, high rhythm; Strengthen reproduction of male animal organ function, promote that muscle growth is the basic demand of male's physical work and breeding poultry and rare animal selection-breeding, fully excavate the buck internal potential of growing fast, seeking non-hormone specificity buck growth promoter also is the pursuit that animal husbandry is produced meat.
At present, in the prior art, usability hormone weighting agent promotes growth of animals or poultry, has meat Chinese medicine residue problem both at home and abroad; Oral steroid hormone also is that human non-disease treatment is abstained from.Injection growth hormone cost height uses inconvenient.In actual life, all can't be applied.Pharmaceutical grade daidzein or total isoflavone are usually used in treating headache, dizziness, dizzy, the tinnitus that hypertension causes as medicine, and angina pectoris is had the obvious treatment effect, and recent sudden deafness is had better effects.Not seeing has this medicine to be used to promote male and the strong and antidotal report of buck.List of references is seen state medical sci-tech publishing house in 1988 12 months " national medical product complete works " p.1127, and People's Health Publisher in March nineteen ninety " Natural Medicine Chemistry " P.277.
The purpose of this invention is to provide a kind of simply, reliably, use the method for non-hormone, natural materials, can make male and reproduction of male animal system enhancement, muscle growth, slow down aging improve the benefit of Production of Livestock and Poultry.
Technical scheme provided by the present invention is as follows:
Strong and the antidotal method of male of a kind of promotion buck, it is characterized in that, use daidzein or total isoflavone or both mixture to press 0.3-100mg/Kg.B.W. dosage, be that animal or male's per kilogram of body weight are used 0.3-100 milligram total isoflavone every day, adopt injection or oral methods.
Strong and the antidotal method of above-mentioned promotion male and buck can be that animal is adopted injection or oral methods, and the male adopts oral methods, and is oral better.Used total isoflavone is daidzein, genistein, U.S. soap isoflavone, formononetin or for wherein with the mixture of any ratio, any combination, it can be pharmaceutical grade, also can be natural plant extract, natural total isoflavone can extract from leguminous plant, and extracting method also is public already technology.
The structural formula of chemical compound involved in the present invention is:
The inventor finds according to neuroendocrinology research and serial buck contrast and experiment, daidzein or total isoflavone raise male and buck endogenous testosterone and level of growth hormone, cause testicualr development, muscle growth and SOD rising, lipid peroxide to descend, thereby promote the body weightening finish, slow down aging.Use natural total isoflavone extract (daidzein, genistein, U.S. soap isoflavone, formononetin), press 0.3-100mg/Kg.B.W dosage, be that the once oral or injection 0.3-100mg total isoflavone of per kilogram of body weight is used for buck, feeding and management method routinely, animal can be improved weightening finish 8-20% after 1-3 month, the muscle weightening finish improves 5-10%, the cockscomb weightening finish improves 20-60%, the testis weightening finish improves 10-30%, serum testosterone content improves 20-50%, growth hormone content improves 10-20%, SOD (superoxide dismutase) activity increases, lipid peroxide descends 45% and 20% in serum and the liver, and the oral above-mentioned same dose of male reaches strong and the defying age purpose equally.Total isoflavone is non-hormone, natural materials, by inducing and increase Endogenous Hormones, rather than replaces endogenous hormones and promotes the buck muscle growth, and is nontoxic, have no side effect.Present technique does not have the species specificity, and technology is simple and reliable, and cost of drugs is low, and it is wide to be suitable for animal range, has good economic benefit.
Embodiment 1: add daidzein (0.5-5mg/Kg.B.W.) male chicken (15 plumage) of feeding in the daily ration, and cockscomb weightening finish 63.9% (P＜0.05), testis weightening finish 34.2% (0.05＜P＜0.1) blood testosterone levels improves 70% (P＜0.01).
Embodiment 2: male rat (14) the daidzein 30mg/kg.B.W. daily gain of feeding every day improves 14.7% (P＜0.05), lower limb flesh is brought up again high by 10.11% (P＜0.01), the buck testosterone concentration improves 70% (P＜0.01), and growth hormone content improves 18.1% (P＜0.05).
Embodiment 3: add the 5-10mg/Kg.b.w. daidzein meat male chicken of red cloth sieve (42 plumage) of feeding in the daily ration, daily gain improves 10.1% (P＜0.01), chest muscle and lower limb flesh improve 6.5% (P＜0.05) and 7.2% (P＜0.05) heavily respectively, and the blood testosterone concentration improves 10.0% (P＜0.05).
The only male normal mouse of embodiment 4:15 (4 week age) the daidzein 10-15mg/Kg.B.W. that feeds, thymus, liver and brain lipid peroxide content reduce 8-13% (P＜0.05), SOD 11% (P＜0.05) of rising.
The only male aged mouse of embodiment 5:20 (16 monthly age), the mice daidzein 40-60mg/Kg.B.W. that feeds, thymus is brought up again high by 124.2%, and liver lipid peroxidation content reduces by 16.9%, and serum lipid peroxide content reduces by 34.8%.
Embodiment 6:28 male rat subcutaneous injection every day daidzein 80-95mg/Kg.B.W., daily gain improves 12.8% (P＜0.05), lower limb flesh is brought up again high by 10.1% (P＜0.01), the buck testosterone concentration improves 40% (P＜0.01), and growth hormone content improves 12.1% (P＜0.05).
Embodiment 7: add daidzein (55-60mg/Kg.B.W.) male chicken (15 plumage) of feeding in the daily ration, and cockscomb weightening finish 65% (P＜0.05), testis weightening finish 36% (0.05＜P＜0.1) blood testosterone levels improves 75% (P＜0.01).
Embodiment 8: add the 30-40mg/Kg.b.w. daidzein meat male chicken of red cloth sieve (40 plumage) of feeding in the daily ration, daily gain improves 12.3% (P＜0.01), chest muscle and lower limb flesh improve 7.5% (P＜0.05) and 7.2% (P＜0.05) heavily respectively, and the blood testosterone concentration improves 10.5% (P＜0.05).
The only male normal mouse of embodiment 9:15 (4 week age) the daidzein 40-50mg/Kg.B.W. that feeds, thymus, liver and brain lipid peroxide content reduce by 14% (P＜0.05), SOD 12% (P＜0.05) of rising.
The only male aged mouse of embodiment 10:15 (15 monthly age), the mice daidzein 85-90mg/Kg.B.W. that feeds, thymus is brought up again high by 120.2%, and liver lipid peroxidation content reduces by 15.9%, and serum lipid peroxide content reduces by 36.8%.
In the above-described embodiments, replace daidzein respectively with genistein, U.S. soap isoflavone, formononetin, perhaps that total isoflavone is included daidzein, genistein, U.S. soap isoflavone, four kinds of material lists of formononetin are used, the effect that all reaches same of using with any ratio, any combination, used total isoflavone can be a pharmaceutical grade, also can be natural extract; The medication of the foregoing description, employing is injected or is fed respectively, and this all is that those of ordinary skill can be accomplished.In addition, the dosage of the foregoing description also is according to approximately giving according to above dosage after the those of ordinary skill estimation animal weight, do not need every animal accurately to weigh in and dose, implementing conveniently.
According to above-mentioned zoopery result, pharmaceutical grade total isoflavone and natural total isoflavone itself are again pure natural, the non-hormone medicines of treatment disease, can infer, and the male uses by this method, reach effect same, this also is that those of ordinary skill can be expected and accomplish.
Claims (9)
1. one kind promotes the strong and antidotal method of male of buck, it is characterized in that, uses total isoflavone to press 0.3-100mg/Kg.B.W. dosage, and promptly animal or male's per kilogram of body weight are used 0.3-100 milligram total isoflavone every day, adopt injection or oral methods.
2. the strong and antidotal method of promotion male according to claim 1 and buck is characterized in that the male adopts oral methods.
3. the strong and antidotal method of promotion male according to claim 1 and 2 and buck is characterized in that, used total isoflavone is daidzein, genistein, U.S. soap isoflavone or formononetin and composition thereof.
4. the strong and antidotal method of promotion male according to claim 1 and 2 and buck is characterized in that used total isoflavone is a pharmaceutical grade.
5. the strong and antidotal method of promotion male according to claim 3 and buck is characterized in that used total isoflavone is a pharmaceutical grade.
6. the strong and antidotal method of promotion male according to claim 1 and 2 and buck is characterized in that used total isoflavone is a natural plant extracts.
7. the strong and antidotal method of promotion male according to claim 3 and buck is characterized in that used total isoflavone is a natural plant extracts.
8. the strong and antidotal method of promotion male according to claim 4 and buck is characterized in that used total isoflavone is a natural plant extracts.
9. the strong and antidotal method of promotion male according to claim 5 and buck is characterized in that used total isoflavone is a natural plant extracts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98111396A CN1126542C (en) | 1998-07-07 | 1998-07-07 | Method for getting roborant and anti-senile of man and buck |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98111396A CN1126542C (en) | 1998-07-07 | 1998-07-07 | Method for getting roborant and anti-senile of man and buck |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1203077A true CN1203077A (en) | 1998-12-30 |
| CN1126542C CN1126542C (en) | 2003-11-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98111396A Expired - Fee Related CN1126542C (en) | 1998-07-07 | 1998-07-07 | Method for getting roborant and anti-senile of man and buck |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006091187A1 (en) * | 2005-02-22 | 2006-08-31 | Landauer Michael R | Isoflavonoids for preventing radiation- and chemotherapy- induced weight loss |
| CN104523733A (en) * | 2014-12-16 | 2015-04-22 | 同济大学 | Pharmaceutical composition with anti-aging effect |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5523087A (en) * | 1995-02-15 | 1996-06-04 | Bio-Virus Research Incorporated | Pharmaceutical compositions for the treatment of diabetic male sexual dysfunction |
-
1998
- 1998-07-07 CN CN98111396A patent/CN1126542C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006091187A1 (en) * | 2005-02-22 | 2006-08-31 | Landauer Michael R | Isoflavonoids for preventing radiation- and chemotherapy- induced weight loss |
| CN104523733A (en) * | 2014-12-16 | 2015-04-22 | 同济大学 | Pharmaceutical composition with anti-aging effect |
| CN104523733B (en) * | 2014-12-16 | 2017-04-12 | 同济大学 | Pharmaceutical composition with anti-aging effect |
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| Publication number | Publication date |
|---|---|
| CN1126542C (en) | 2003-11-05 |
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