CN1190000A - Efficient difluoric antiseptic toothpaste - Google Patents
Efficient difluoric antiseptic toothpaste Download PDFInfo
- Publication number
- CN1190000A CN1190000A CN97105074A CN97105074A CN1190000A CN 1190000 A CN1190000 A CN 1190000A CN 97105074 A CN97105074 A CN 97105074A CN 97105074 A CN97105074 A CN 97105074A CN 1190000 A CN1190000 A CN 1190000A
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- pure
- efficient
- difluoric
- tooth
- antiseptic
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Abstract
The present invention relates to composition containing fluoride and the antiseptic toothpaste uses sodium fluoride and sodium fluorophosphate as caries preventing agent, Yujiechun as antiseptic, zeolite powder as friction agent. The said toothpaste can fluorate tooth apatite to form apatite fluorie, remineralize decalcificated tooth tissue and resist acid erosion a caries efficiently; and it can control the formation of tooth patches without affecting ecological environment of oral cavity. It has several functions of preventing caries and periodontitis, cleaning tooth and keeping oral cavity clean.
Description
The invention belongs to dressing and use the preparation field, particularly a kind of preparation that contains fluorine compounds.
Oral disease comprises dental caries (tooth cavity), dental plaque, gingivitis and odontoseisis, uses fluoride and can reduce the tooth tooth cavity, but powerless to gingivitis and periodontal, and have the problem that makes loss of tooth.The various toothpaste that existing market is produced, be the individual event medicated toothpaste, do not contain pure as jade pure in two fluorine (sodium fluoride and sodium monofluorophosphate) toothpaste, zeolite powder, pure as jade pure MP (2,4,4 '-three chloro-2 '-dihydroxy diphenyl ether) be a kind of non-ionic broad-spectrum antimicrobial agent, it is efficient, low toxicity is without the Liver and kidney metabolism, the effect extremely that presses down for the exclusive excellence of pathogenic bacterium in the oral cavity, and zeolite powder has stable fluorine effect, the friction valve height, the effect that attrition value is low, therefore use the individual event medicated toothpaste, the patient who the trouble gingivitis is suffered from simultaneously dental caries again can not meet the demands, and it is very inconvenient that its self health care is selected.
The purpose of this invention is to provide a kind of toothpaste that contains preventing decayed tooth, anti-plaque multiple efficacies.
The object of the present invention is achieved like this: a kind of efficient difluoric antiseptic toothpaste is characterized in that key component is (percentage by weight):
Sodium fluoride 0.10～0.20 sodium monofluorophosphate 0.5～1.0 is pure as jade by pure 0.2～0.4
Zeolite powder 40.00～50.00
Preparation technology of the present invention: at first select materials, measure by mentioned component, in blending tank, dissolve pure as jade pure with propylene glycol, with water and milkization, feed intake by prescription,, add zeolite powder afterwards and mediate, mix and stir with about 48 hours of carboxylic cellulose formiate dissolving glue, ageing, grind and three times repeatedly with colloid mill, make it to form the mastic of mix homogeneously exquisiteness, with the vacuum pump degassing, measure tubulature, tube sealing, vanning with filling machine after the quality inspection then.
The present invention's host of filling a prescription selects for use two fluorine (sodium fluoride and sodium monofluorophosphate) to do caries preventive agent, the pure as jade pure antibacterial of doing, zeolite powder is made abrasive, can fluoridize tooth body apatite and form fluor-apatite, promote the remineralization of decalcification tissue of tooth function, has efficient antiacid erosion preventing decayed tooth usefulness, and can not influence under the ecological environment of oral cavity, efficiently control dental plaque and form, have the effectiveness of brightening, its mastic friction value height, attrition value are low, having absorption and ion exchange effect, can stablize fluorine and imitate, is caries prevention, periodontal disease, cleaning teeth is promoted the multi-efficiency toothpaste of oral cavity health.
Experimental data of the present invention is as follows:
1. antibacterial experiment (in vitro carrying out) with agar diffusion method
Suppress streptococcus 18.75～37.5
Suppress staphylococcus 4.7～9.4
2. antiplaque experiment
Antiplaque index 0.30
3. fluorine stability is measured
Development under long-term fluoride stability is measured＞800～1000P.P.M
4. mastic friction valve
Mastic friction valve 1.5～2.0
Embodiment:
Present embodiment select for use sodium fluoride, sodium monofluorophosphate with antiacid erosion, caries prevention promote tooth body remineralization, with pure as jade pure anti-plaque, the whitening effect of reaching, select Chile saltpeter and Borax for use in case dentin acid cold, desensitize, reach antiinflammatory, hemostatic purpose, adopt carbamide can eliminate halitosis, propylene glycol and sorbitol can make mastic preserve moisture, the carboxylic cellulose formiate is adjusted mastic viscosity, and zeolite powder is used to clean the teeth, anti-tartar.The present invention batching determines according to pure as jade pure consumption, and when pure as jade pure content is 3.0%, other weight percentages of components is:
Sodium fluoride 0.14 sodium monofluorophosphate 0.76 is pure as jade by pure 0.30
Chile saltpeter 2.00 Boraxs 0.20 carbamide 1.5
Propylene glycol 3.00 sorbitol 12.00 carboxymethyl celluloses 1.20
Sodium lauryl sulfate 2.50 silicon dioxide 2.50 essence 1.10
Saccharin sodium 0.25 zeolite powder 42.5 water 30.05
During making, at first select materials, measure by mentioned component, in blending tank, dissolve with propylene glycol pure as jade pure, with water and milkization.Feed intake by prescription,, add zeolite powder afterwards and mediate, mix and stir with about 48 hours of carboxylic cellulose formiate dissolving glue, ageing, grind and three times repeatedly with colloid mill, make it to form the mastic of mix homogeneously exquisiteness, with the vacuum pump degassing, measure tubulature, tube sealing, vanning with filling machine after the quality inspection then.
Claims (3)
1. efficient difluoric antiseptic toothpaste is characterized in that key component is (percentage by weight):
Sodium fluoride 0.10～0.20 sodium monofluorophosphate 0.5～1.0 is pure as jade by pure 0.2～0.4
Zeolite powder 40.00～50.00
2. efficient difluoric antiseptic toothpaste according to claim 1 is characterized in also containing following component (percentage by weight):
Propylene glycol 2.00～3.00 sorbitol 10.0～20.0 carboxymethyl celluloses 1.0～1.5
Water 25.00～35.00
3. efficient difluoric antiseptic toothpaste according to claim 1 and 2, its preparation technology is: at first select materials, measure by mentioned component, in blending tank, dissolve pure as jade pure with propylene glycol, with water and milkization, feed intake by prescription, with about 48 hours of carboxylic cellulose formiate dissolving glue, ageing, adding zeolite powder afterwards mediates, mixes and stir, grind and three times repeatedly with colloid mill, make it to form behind the mastic of mix homogeneously, after quality inspection, measure tubulature, tube sealing, vanning with filling machine with the vacuum pump degassing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97105074A CN1190000A (en) | 1997-02-03 | 1997-02-03 | Efficient difluoric antiseptic toothpaste |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97105074A CN1190000A (en) | 1997-02-03 | 1997-02-03 | Efficient difluoric antiseptic toothpaste |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1190000A true CN1190000A (en) | 1998-08-12 |
Family
ID=5167635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97105074A Pending CN1190000A (en) | 1997-02-03 | 1997-02-03 | Efficient difluoric antiseptic toothpaste |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1190000A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100438851C (en) * | 2002-12-13 | 2008-12-03 | 宝洁公司 | Method of enhancing fluoridation and mineralization of teeth |
| CN111518636A (en) * | 2020-05-20 | 2020-08-11 | 张孙玮 | Portable solid cleaning composition and preparation method thereof |
-
1997
- 1997-02-03 CN CN97105074A patent/CN1190000A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100438851C (en) * | 2002-12-13 | 2008-12-03 | 宝洁公司 | Method of enhancing fluoridation and mineralization of teeth |
| CN111518636A (en) * | 2020-05-20 | 2020-08-11 | 张孙玮 | Portable solid cleaning composition and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |