CN118345101A - 用于用抗bcma免疫治疗来治疗癌症的组合物和方法 - Google Patents

用于用抗bcma免疫治疗来治疗癌症的组合物和方法 Download PDF

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Publication number
CN118345101A
CN118345101A CN202410367847.7A CN202410367847A CN118345101A CN 118345101 A CN118345101 A CN 118345101A CN 202410367847 A CN202410367847 A CN 202410367847A CN 118345101 A CN118345101 A CN 118345101A
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car
cell
cells
seq
cancer
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Chinese (zh)
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迪娜·施奈德
朱忠玉
博罗·德罗普利奇
庞·科·武
利亚·玛丽·阿拉班扎
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Lentigen Technology Inc
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Lentigen Technology Inc
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
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    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4214—Receptors for cytokines
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K2319/00—Fusion polypeptide
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CN202410367847.7A 2019-05-30 2020-05-29 用于用抗bcma免疫治疗来治疗癌症的组合物和方法 Pending CN118345101A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962854574P 2019-05-30 2019-05-30
US62/854,574 2019-05-30
PCT/US2020/035287 WO2020243546A1 (en) 2019-05-30 2020-05-29 Compositions and methods for treating cancer with anti-bcma immunotherapy
CN202080055307.5A CN114364801B (zh) 2019-05-30 2020-05-29 用于用抗bcma免疫治疗来治疗癌症的组合物和方法

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CN202080055307.5A Active CN114364801B (zh) 2019-05-30 2020-05-29 用于用抗bcma免疫治疗来治疗癌症的组合物和方法

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US (3) US11052112B2 (https=)
EP (1) EP3976653A1 (https=)
JP (2) JP7677908B2 (https=)
CN (2) CN118345101A (https=)
AU (1) AU2020283027A1 (https=)
CA (1) CA3140102A1 (https=)
WO (1) WO2020243546A1 (https=)

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CA3140102A1 (en) 2019-05-30 2020-12-03 Dina SCHNEIDER Compositions and methods for treating cancer with anti-bcma immunotherapy
CN114149505B (zh) * 2021-01-12 2022-11-04 北京门罗生物科技有限公司 治疗b细胞相关疾病的免疫细胞、制备方法及其应用
AU2023314413A1 (en) 2022-07-28 2025-02-13 Lentigen Technology, Inc. Chimeric antigen receptor therapies for treating solid tumors
CN119907810A (zh) 2022-08-26 2025-04-29 莱蒂恩技术公司 用于用全人抗cd20/cd19免疫治疗来治疗癌症的组合物和方法
WO2025171388A1 (en) 2024-02-09 2025-08-14 Dispatch Biotherapeutics, Inc. Engineered cancer antigens with modified domains and related methods and uses
WO2025171383A2 (en) 2024-02-09 2025-08-14 Dispatch Biotherapeutics, Inc. Engineered cancer antigens and related methods and uses
WO2026006682A1 (en) 2024-06-27 2026-01-02 Lentigen Technology, Inc. Chimeric antigen receptor therapies for treating cancer with il7fc armored car-t cells
WO2026006767A1 (en) 2024-06-28 2026-01-02 Dispatch Biotherapeutics, Inc. Tethered il-9/il-9r and related engineered cells and methods
WO2026072709A1 (en) 2024-09-25 2026-04-02 Orna Therapeutics, Inc. Chimeric antigen receptors targeting bcma

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