CN118304527A - Pressure control variability ventilation method and system based on capacity guidance and breathing machine - Google Patents

Abstract

The invention relates to the technical field of medical equipment, in particular to a pressure control variability ventilation method and system based on capacity guidance and a breathing machine. The method comprises the following steps: step 1: adding the set tidal volume variation dV to the set ideal tidal volume VI to obtain a target tidal volume VT; step 2: acquiring a difference delta V between the actual tidal volume Vt of the user and the target tidal volume VT of the breathing cycle, and step 3: calculating an ideal pressure P for the present breathing cycle based on the difference Δv; calculating the pressure variation dP of the present breathing cycle based on the difference Δv; step 4: calculating the driving pressure delta P of the ventilation device through the ideal pressure P of the breathing cycle and the pressure variation degree dP of the breathing cycle, and controlling the ventilation device to operate based on the driving pressure delta P in the next breathing cycle; step 5: and (3) taking the next breathing cycle in the step (4) as the breathing cycle of the step (2), and returning to the step (2) until the actual tidal volume Vt of the user reaches the target tidal volume VT.

Description

Pressure control variability ventilation method and system based on capacity guidance and breathing machine

Technical Field

The invention relates to the technical field of medical equipment, in particular to a pressure control variability ventilation method and system based on capacity guidance and a breathing machine.

Background

Mechanical ventilation plays a significant role in the medical device arts. However, conventional mechanical ventilation modes can only provide a fixed tidal volume or inspiratory pressure, and there is a certain variability in true spontaneous breathing, and a sigh can appear intermittently, and the tidal volume, the respiratory rate and the inspiratory flow rate all fluctuate within a certain range. The existing mechanical ventilation air supply mode is single, which is completely different from spontaneous breathing.

Variability is a compensatory capability of an organism that is adaptable to changing external environments. In a healthy state, there is significant variability in heart rate, arterial blood pressure, respiratory rate, lung ventilation and blood flow distribution, and white blood cell count, among others. Studies have shown that healthy adults typically breathe spontaneously in calm conditions with 33%, 21% and 18% variability in tidal volume, respiratory rate and inspiratory time, respectively, which can maintain the ventilatory balance of the body, reduce pulmonary stress and strain, and are very beneficial to the human body.

In some situations, the inherent variability of the respiratory system of an organism may be reduced. Mechanical ventilation cannot accommodate these variability changes due to its single delivery pattern, and for mechanical ventilation users, a decrease in respiratory variability can easily lead to withdrawal failure.

Disclosure of Invention

The invention aims to overcome the defect that the breathing variability change of a user cannot be adapted, so as to provide a volume-oriented pressure control variability ventilation method, a volume-oriented pressure control variability ventilation system and a breathing machine comprising the system.

In order to solve the technical problems, the pressure control variability ventilation method based on capacity guidance provided by the technical scheme of the invention relates to a ventilation device, which comprises the following steps: 1. a method of pressure control variability ventilation based on volume steering, involving a ventilation device, comprising:

Step 1: adding the set tidal volume variation dV to the set ideal tidal volume VI to obtain a target tidal volume VT;

step 2: a difference DeltaV between the monitored actual tidal volume Vt of the user and the target tidal volume VT of the present respiratory cycle is obtained,

Step 3: calculating the ideal pressure P of the present breathing cycle by the difference DeltaV and the ideal pressure Ppre of the previous breathing cycle; calculating the pressure variation dP of the present breathing cycle by the difference DeltaV and the pressure variation dPpre of the previous breathing cycle;

Step 4: calculating the driving pressure delta P of the ventilation device through the ideal pressure P of the breathing cycle and the pressure variation degree dP of the breathing cycle, and controlling the ventilation device to operate based on the driving pressure delta P in the next breathing cycle;

Step 5: and (3) taking the next breathing cycle in the step (4) as the breathing cycle of the step (2), and returning to the step (2) until the actual tidal volume Vt of the user reaches the target tidal volume VT.

As an improvement of the above method, the step 1 specifically includes:

VT＝VI+dV×a

where a is a gaussian coefficient following normal distribution.

As an improvement of the above method, the step2 specifically includes:

calculating an actual tidal volume Vt of the user by monitoring the obtained actual inspiratory tidal volume Vti of the user and monitoring the obtained actual expiratory tidal volume Vte of the user:

Vt＝(Vti+Vte)/2

acquiring a difference DeltaV between an actual tidal volume Vt of a user and a target tidal volume VT of the present respiratory cycle

ΔV＝Vt–VT。

As an improvement of the above method, the step3 specifically includes:

The ideal pressure P for the present breathing cycle is calculated from the difference Δv and the ideal pressure Ppre for the previous breathing cycle:

P＝Ppre+k1×ΔV

Wherein k1 is a first parameter, k1= -1/(1000×c), and C is the compliance of the respiratory system of the user obtained by monitoring; when the previous respiratory cycle is the first respiratory cycle, the ideal pressure Ppre of the previous respiratory cycle is:

Ppre＝VI/C

The pressure variation dP for the present breathing cycle is calculated by the difference Δv and the pressure variation dPpre for the previous breathing cycle:

dP＝dPpre+k2×ΔV

where k2 is a second parameter, k2=k1/100×a, a is a gaussian coefficient subject to normal distribution; when the previous respiratory cycle is the first respiratory cycle, the pressure variation dPpre in the previous respiratory cycle is:

dPpre＝dV/C。

As an improvement of the above method, the step4 specifically includes:

the driving pressure delta P of the ventilation system is calculated through the ideal pressure P of the breathing cycle and the pressure variation degree dP of the breathing cycle:

ΔP＝P+dP×a

Wherein a is a Gaussian coefficient obeying normal distribution;

the ventilation system is operated based on the driving pressure deltap in the next breathing cycle.

To achieve another object of the present invention, the present invention also provides a pressure control variability ventilation system based on capacity guidance, comprising a ventilation device and a control module; wherein,

The control module is used for adding the set tidal volume variation dV to the set ideal tidal volume VI to obtain a target tidal volume VT; the method comprises the steps of acquiring a difference delta V between the monitored actual tidal volume Vt of a user in the breathing cycle and the target tidal volume VT, and calculating an ideal pressure P in the breathing cycle through the difference delta V and an ideal pressure Ppre in the last breathing cycle; calculating the pressure variation dP of the present breathing cycle by the difference DeltaV and the pressure variation dPpre of the previous breathing cycle; the method comprises the steps of calculating the driving pressure delta P of the ventilation device through the ideal pressure P of the breathing cycle and the pressure variation degree dP of the breathing cycle, and controlling the ventilation device to operate based on the driving pressure delta P in the next breathing cycle;

The ventilation device works based on the ventilation system driving pressure delta P and outputs a corresponding tidal volume.

To achieve another object of the present invention, the present invention also provides a ventilator comprising the volume-based pilot-based pressure control variability ventilation system described above.

Compared with the prior art, the ventilation target provided by the invention has the advantages that a certain degree of variation is added to the ventilation target, the physiological requirement of a user is met, and the pressure of the ventilation device can be adjusted in a self-adaptive manner so that the actual tidal volume of the user gradually reaches the target tidal volume. The invention also adds a certain degree of variation in pressure regulation, which can improve the comfort of users and is more beneficial to quickening the machine withdrawal.

Drawings

Fig. 1 is a schematic diagram of a volume-oriented pressure control variability ventilation method provided by the present invention.

Detailed Description

The technical scheme provided by the invention is further described below by combining with the embodiment.

Example 1

The present embodiment provides a pressure control variability ventilation method based on capacity guidance, as shown in fig. 1, including:

Step 1: adding the set tidal volume variation dV to the set ideal tidal volume VI to obtain a target tidal volume VT;

step 2: a difference DeltaV between the monitored actual tidal volume Vt of the user and the target tidal volume VT of the present respiratory cycle is obtained,

Step 3: calculating the ideal pressure P of the present breathing cycle by the difference DeltaV and the ideal pressure Ppre of the previous breathing cycle; calculating the pressure variation dP of the present breathing cycle by the difference DeltaV and the pressure variation dPpre of the previous breathing cycle;

Step 4: calculating the driving pressure delta P of the ventilation device through the ideal pressure P of the breathing cycle and the pressure variation degree dP of the breathing cycle, and controlling the ventilation device to operate based on the driving pressure delta P in the next breathing cycle;

Step 5: and (3) taking the next breathing cycle in the step (4) as the breathing cycle of the step (2), and returning to the step (2) until the actual tidal volume Vt of the user reaches the target tidal volume VT.

The method can be realized by the following specific steps.

1. Operator input parameters are obtained. The system is capacity-oriented, i.e., achieves the user tidal volume desired by the operator, so the input parameters include the desired tidal volume VI and tidal volume variation dV.

2. Generating a gaussian coefficient a compliant with a normal distribution, then the target tidal volume VT is:

VT＝VI+dV×a

thereby adding a degree of variability to the tidal volume of the user.

3. The actual tidal volume Vt of the user is monitored by a flow sensor:

Vt＝(Vti+Vte)/2

where Vti is the monitored inspiratory tidal volume of the user, vte is the monitored expiratory tidal volume of the user, and the average of the two is taken as the actual tidal volume of the user.

4. Obtaining a difference DeltaV between the actual tidal volume of the user and the target tidal volume:

ΔV＝Vt–VT

5. the system is essentially pressure controlled ventilation, i.e. by adjusting the driving pressure deltap from breath to breath, so that the user's actual tidal volume Vt approaches the target tidal volume Vt; wherein,

ΔP＝P+dP×a

Wherein,

P＝Ppre+k1×ΔV

dP＝dPpre+k2×ΔV

k1＝-1/(1000×C)

k2＝k1/100×a

Wherein k1 is a first parameter, k2 is a second parameter, P is an ideal pressure of the present breathing cycle, ppre is an ideal pressure of the last breathing cycle, dP is a pressure variation of the present breathing cycle, dPpre is a pressure variation of the last breathing cycle, and C is a compliance of the breathing system of the user obtained by real-time monitoring. The ideal pressure has an initial value of VI/C and the pressure variation has an initial value of dV/C.

The parameters are updated from respiratory cycle to respiratory cycle, and the actual tidal volume Vt of the user gradually reaches the preset target tidal volume VT through the adjustment of the driving pressure delta P.

6. And returning to the step 2 to repeat the process after the actual tidal volume Vt reaches the preset target tidal volume VT. Variability in ventilation can be achieved by constantly adjusting.

Example 2

The embodiment provides a pressure control variability ventilation system based on capacity guidance, which comprises a ventilation device and a control module; wherein,

The control module is used for adding the set tidal volume variation dV to the set ideal tidal volume VI to obtain a target tidal volume VT; the method comprises the steps of acquiring a difference delta V between the monitored actual tidal volume Vt of a user in the breathing cycle and the target tidal volume VT, and calculating an ideal pressure P in the breathing cycle through the difference delta V and an ideal pressure Ppre in the last breathing cycle; calculating the pressure variation dP of the present breathing cycle by the difference DeltaV and the pressure variation dPpre of the previous breathing cycle; the method comprises the steps of calculating the driving pressure delta P of the ventilation device through the ideal pressure P of the breathing cycle and the pressure variation degree dP of the breathing cycle, and controlling the ventilation device to operate based on the driving pressure delta P in the next breathing cycle;

The ventilation device works based on the ventilation system driving pressure delta P and outputs a corresponding tidal volume.

Example 3

This embodiment provides a ventilator comprising the volume-based guided pressure control variability ventilation system provided in embodiment 2.

Finally, it should be noted that the above embodiments are only for illustrating the technical solution of the present invention and are not limiting. Although the present invention has been described in detail with reference to the embodiments, it should be understood by those skilled in the art that modifications and equivalents may be made thereto without departing from the spirit and scope of the present invention, which is intended to be covered by the appended claims.

Claims (7)

1. A method of pressure control variability ventilation based on volume steering, involving a ventilation device, comprising:

Step 1: adding the set tidal volume variation dV to the set ideal tidal volume VI to obtain a target tidal volume VT;

Step 2: acquiring a difference DeltaV between the monitored actual tidal volume Vt of the user in the breathing cycle and the target tidal volume VT;

Step 3: calculating the ideal pressure P of the present breathing cycle by the difference DeltaV and the ideal pressure Ppre of the previous breathing cycle; calculating the pressure variation dP of the present breathing cycle by the difference DeltaV and the pressure variation dPpre of the previous breathing cycle;

Step 4: calculating the driving pressure delta P of the ventilation device through the ideal pressure P of the breathing cycle and the pressure variation degree dP of the breathing cycle, and controlling the ventilation device to operate based on the driving pressure delta P in the next breathing cycle;

Step 5: and (3) taking the next breathing cycle in the step (4) as the breathing cycle of the step (2), and returning to the step (2) until the actual tidal volume Vt of the user reaches the target tidal volume VT.

2. The method of capacity-guided pressure control variability ventilation according to claim 1, wherein step 1 specifically comprises:

VT＝VI+dV×a

where a is a gaussian coefficient following normal distribution.

3. The method of capacity-guided pressure control variability ventilation according to claim 1, wherein step 2 comprises:

calculating an actual tidal volume Vt of the user by monitoring the obtained actual inspiratory tidal volume Vti of the user and monitoring the obtained actual expiratory tidal volume Vte of the user:

Vt＝(Vti+Vte)/2

acquiring a difference DeltaV between an actual tidal volume Vt of a user and a target tidal volume VT of the present respiratory cycle

ΔV＝Vt–VT。

4. The method of capacity-guided pressure control variability ventilation according to claim 1, wherein step 3 specifically comprises:

The ideal pressure P for the present breathing cycle is calculated from the difference Δv and the ideal pressure Ppre for the previous breathing cycle:

P＝Ppre+k1×ΔV

Wherein k1 is a first parameter, k1= -1/(1000×c), and C is the compliance of the respiratory system of the user obtained by monitoring; when the previous respiratory cycle is the first respiratory cycle, the ideal pressure Ppre of the previous respiratory cycle is:

Ppre＝VI/C

The pressure variation dP for the present breathing cycle is calculated by the difference Δv and the pressure variation dPpre for the previous breathing cycle:

dP＝dPpre+k2×ΔV

where k2 is a second parameter, k2=k1/100×a, a is a gaussian coefficient subject to normal distribution; when the previous respiratory cycle is the first respiratory cycle, the pressure variation dPpre in the previous respiratory cycle is:

dPpre＝dV/C。

5. The method of capacity-guided pressure control variability ventilation according to claim 1, wherein step 4 specifically comprises:

the driving pressure delta P of the ventilation system is calculated through the ideal pressure P of the breathing cycle and the pressure variation degree dP of the breathing cycle:

ΔP＝P+dP×a

Wherein a is a Gaussian coefficient obeying normal distribution;

the ventilation system is operated based on the driving pressure deltap in the next breathing cycle.

6. A volume-guided pressure control variability ventilation system comprising a ventilation device, further comprising: a control module; wherein,

The control module is used for adding the set tidal volume variation dV to the set ideal tidal volume VI to obtain a target tidal volume VT; the method comprises the steps of acquiring a difference delta V between the monitored actual tidal volume Vt of a user in the breathing cycle and the target tidal volume VT, and calculating an ideal pressure P in the breathing cycle through the difference delta V and an ideal pressure Ppre in the last breathing cycle; calculating the pressure variation dP of the present breathing cycle by the difference DeltaV and the pressure variation dPpre of the previous breathing cycle; the method comprises the steps of calculating the driving pressure delta P of the ventilation device through the ideal pressure P of the breathing cycle and the pressure variation degree dP of the breathing cycle, and controlling the ventilation device to operate based on the driving pressure delta P in the next breathing cycle;

The ventilation device works based on the ventilation system driving pressure delta P and outputs a corresponding tidal volume.

7. A ventilator comprising the volume-based pilot-based pressure control variability ventilation system of claim 6.