CN118294688A - Pipetting system and use method - Google Patents

Abstract

The invention relates to the technical field of nuclear chemical industry, in particular to a pipetting system and a using method thereof. A pipetting system comprising: the shielding box body is provided with an accommodating space; the lifting assembly is arranged in the accommodating space and comprises a lifter and a lifting plate, the movable end of the lifter is fixedly connected with the lifting plate, the lifting plate is suitable for placing a sample bottle, and the sample bottle is suitable for placing radioactive feed liquid to be measured; the liquid injection assembly comprises a liquid injection needle which is arranged in the accommodating space and corresponds to the liquid taking level; the cuvette pool is arranged in the accommodating space and is connected with the liquid injection needle tube path; the detection component is arranged in the accommodating space and comprises a long-optical-path photometric analyzer; and the mechanical arm is arranged in the accommodating space. The invention solves the problems that when a radioactive liquid sample is sampled and analyzed, various operation steps are carried out by the mechanical arm, so that the operation steps are complex and the operation convenience is affected, thereby providing a pipetting system and a using method.

Description

Pipetting system and use method

Technical Field

The invention relates to the technical field of nuclear chemical industry, in particular to a pipetting system and a using method thereof.

Background

The pipetting device is one of the analytical instruments commonly used in analytical laboratories and is used for realizing the operations of conveying, transferring, extracting and the like of liquid among different standard liquid containers. Currently, a common liquid sample sampling pipetting operation is to insert the needle of a syringe into a liquid sample container and manually or automatically withdraw the syringe plunger until the liquid sample in the container no longer flows in. When the radioactive liquid sample is subjected to necessary sampling analysis among multiple analysis stations, corresponding pipetting operations are often carried out in a shielding box through a multi-channel valve equipped with an injection pump, and various operation steps are carried out through a mechanical arm, so that the operation steps of the mechanical arm are complex, and the operation convenience is affected.

Disclosure of Invention

Therefore, the technical problem to be solved by the invention is to overcome the defects that in the prior art, when a radioactive liquid sample is sampled and analyzed, various operation steps are performed through a mechanical arm, so that the operation steps are complex and the operation convenience is affected, and therefore, the pipetting system and the using method are provided.

In order to solve the above problems, the present invention provides a pipetting system comprising:

The shielding box body is provided with an accommodating space;

The lifting assembly is arranged in the accommodating space and comprises a lifter and a lifting plate, the movable end of the lifter is fixedly connected with the lifting plate, the lifting plate is suitable for placing a sample bottle, and the sample bottle is suitable for placing radioactive feed liquid to be measured;

the liquid injection assembly comprises a liquid injection needle which is arranged in the accommodating space and corresponds to the liquid taking level;

The cuvette pool is arranged in the accommodating space and is connected with the liquid injection needle tube way;

the detection assembly is arranged in the accommodating space and comprises a long-optical-path photometric analyzer;

and the mechanical arm is arranged in the accommodating space.

Optionally, the lifter plate is equipped with first liquid level of getting, first liquid level of getting is suitable for placing the sample bottle, the lifting assembly still includes base and mount, the fixed first notes liquid needle that is equipped with on the mount, first notes liquid needle corresponds the setting with first liquid level of getting.

Optionally, the device further comprises a first pipeline, wherein the first pipeline is provided with a first liquid injection needle, a cuvette pool and a first liquid storage ring.

Optionally, the lifter plate is equipped with the second and gets the liquid level, the second is got the liquid level and is suitable for placing cuvette or sample bottle, fixed the being equipped with second notes liquid needle on the mount, the second notes liquid needle is got the liquid level with the second and is set up.

Optionally, the device further comprises a second pipeline, and a second liquid injection needle and a second liquid storage ring are arranged on the second pipeline.

Optionally, the detection assembly further comprises a temporary storage table and an infrared detection table, wherein the temporary storage table is suitable for placing a sample bottle, and the infrared detection table is suitable for placing a cuvette.

Optionally, the cleaning power assembly is arranged outside the shielding box body, the cleaning power assembly comprises a six-way distribution valve, one end of the first pipeline, which is away from the first liquid injection needle, is connected with the six-way distribution valve, and one end of the second pipeline, which is away from the second liquid injection needle, is connected with the six-way distribution valve.

Optionally, the cleaning power assembly further comprises a syringe pump, a three-way valve and a current carrying liquid pool, wherein the current carrying liquid pool is connected with the six-way distribution valve through a third pipeline, the current carrying liquid pool is connected with the three-way valve through a fourth pipeline, the three-way valve is connected with the syringe pump through a fifth pipeline, and the three-way valve is connected with the six-way distribution valve through a sixth pipeline.

The use method of the pipetting system comprises the steps that under a working state, a mechanical arm places a sample bottle on a lifting plate, a lifter pushes the lifting plate to move towards a liquid injection needle until the liquid injection needle stretches into the sample bottle, the liquid injection needle extracts radioactive to-be-measured liquid in the sample bottle, the radioactive to-be-measured liquid flows into a cuvette pool through the liquid injection needle, and a long-optical-path photometric analyzer irradiates the cuvette pool to analyze the radioactive to-be-measured liquid in the cuvette pool.

Optionally, the method comprises the following steps:

1) Starting the injection pump to discharge the gas in the first pipeline through the six-way distribution valve and the three-way valve, filling the first pipeline with the carrier liquid, and conveying the carrier liquid to the first liquid injection needle through the first pipeline;

2) Starting a mechanical arm to move a sample bottle containing the radioactive material liquid to be detected from a temporary storage table to a first liquid taking level of a lifting plate;

3) Controlling the lifting device to lift, so that the lifting plate drives the sample bottle to lift until the first liquid injection needle is inserted into the sample bottle;

4) Starting an injection pump, and enabling radioactive to-be-measured feed liquid in a sample bottle to enter a cuvette pool by means of a six-way distribution valve under the assistance of carrier liquid, wherein the radioactive to-be-measured feed liquid enters a first liquid storage ring through the cuvette pool;

5) Taking the flowing cuvette cell as a measuring cell, and detecting and analyzing the radioactive to-be-measured feed liquid left in the cuvette cell by using a long-optical-path photometric analyzer;

6) After ultraviolet and visible luminosity analysis is completed, starting the injection pump to reversely push the liquid in the first pipeline under the assistance of the carrier liquid through the cooperation of the six-way distribution valve and the three-way valve, so that the washing of the carrier liquid contrast color dish pool is realized.

The technical scheme of the invention has the following advantages:

1. The present invention provides a pipetting system comprising: the shielding box body is provided with an accommodating space; the lifting assembly is arranged in the accommodating space and comprises a lifter and a lifting plate, the movable end of the lifter is fixedly connected with the lifting plate, the lifting plate is suitable for placing a sample bottle, and the sample bottle is suitable for placing radioactive feed liquid to be measured; the liquid injection assembly comprises a liquid injection needle which is arranged in the accommodating space and corresponds to the liquid taking level; the cuvette pool is arranged in the accommodating space and is connected with the liquid injection needle tube path; the detection component is arranged in the accommodating space and comprises a long-optical-path photometric analyzer; and the mechanical arm is arranged in the accommodating space.

Under the operating condition, the mechanical arm places the sample bottle on the lifting plate, and the lifter promotes the lifting plate to move towards the liquid injection needle until the liquid injection needle stretches into the sample bottle, and the liquid injection needle extracts the radioactive material liquid to be detected in the sample bottle, and the radioactive material liquid to be detected flows into the cuvette cell through the liquid injection needle, and the long-optical-path photometric analyzer irradiates the cuvette cell so as to analyze the radioactive material liquid to be detected in the cuvette cell. Through the process, only the mechanical arm is needed to carry out simple operation, so that operation steps are simplified, and operation convenience is improved.

2. The lifting plate is provided with a first liquid taking level, the first liquid taking level is suitable for placing a sample bottle, the lifting assembly further comprises a base and a fixing frame, a first liquid injection needle is fixedly arranged on the fixing frame, and the first liquid injection needle is arranged corresponding to the first liquid taking level. The first liquid injection needle is fixed through the fixing frame, so that the first liquid injection needle and the first liquid taking level are correspondingly arranged.

3. The pipetting system provided by the invention further comprises a first pipeline, wherein the first pipeline is provided with a first liquid injection needle, a cuvette pool and a first liquid storage ring, and the first liquid injection needle, the cuvette pool and the first liquid storage ring are connected in series through the first pipeline.

4. According to the pipetting system provided by the invention, the lifting plate is provided with the second liquid taking level, the second liquid taking level is suitable for placing the cuvette or the sample bottle, the second liquid injection needle is fixedly arranged on the fixing frame and corresponds to the second liquid taking level, so that the cuvette or the sample bottle is placed through the second liquid taking level, and the second liquid injection needle corresponds to the second liquid taking level.

5. The liquid transferring system provided by the invention further comprises a second pipeline, wherein the second pipeline is provided with a second liquid injection needle and a second liquid storage ring, and the second liquid injection needle is communicated with the second liquid storage ring through the second pipeline.

6. The detection assembly of the pipetting system provided by the invention further comprises a temporary storage table and an infrared detection table, wherein the temporary storage table is suitable for placing a sample bottle, the infrared detection table is suitable for placing a cuvette, the sample bottle is enabled to reciprocate between the temporary storage table and a liquid taking level through operating a mechanical arm, and the infrared detection table is used for detecting radioactive material liquid to be detected in the cuvette.

7. The invention provides a pipetting system which further comprises a cleaning power assembly, wherein the cleaning power assembly is arranged outside a shielding box body and comprises a six-way distribution valve, one end of a first pipeline, which is away from a first liquid injection needle, is connected with the six-way distribution valve, and one end of a second pipeline, which is away from a second liquid injection needle, is connected with the six-way distribution valve. The cleaning power assembly is arranged outside the shielding box body, so that the cleaning assembly is prevented from being radiated by the radioactive material liquid to be detected in the shielding box body, the service life of the cleaning power assembly is prolonged, and the radioactive damage to the cleaning power assembly in the sampling operation process is avoided.

8. The invention provides a pipetting system, which comprises a cleaning power assembly, a syringe pump, a three-way valve and a current-carrying liquid pool, wherein the current-carrying liquid pool is connected with a six-way distribution valve through a third pipeline, the current-carrying liquid pool is connected with the three-way valve through a fourth pipeline, the three-way valve is connected with the syringe pump through a fifth pipeline, the three-way valve is connected with the six-way distribution valve through a sixth pipeline, and the first pipeline and the second pipeline are cleaned through current-carrying liquid in the current-carrying liquid pool or radioactive to-be-detected liquid in a first liquid injection needle and a second liquid injection needle is sucked through matching of the syringe pump, the three-way valve, the six-way distribution valve and the current-carrying liquid pool.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are needed in the description of the embodiments or the prior art will be briefly described, and it is obvious that the drawings in the description below are some embodiments of the present invention, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.

Fig. 1 is a schematic view of a lifting assembly and a mechanical arm in a shielding box according to an embodiment of the present invention;

fig. 2 is a schematic diagram of a pipetting system provided in an embodiment of the invention.

Reference numerals illustrate: 1. a cuvette; 2. a sample bottle; 3. a second liquid level is taken; 4. a first liquid level; 5. a bracket; 6. a lifter; 7. a quick water and electricity joint; 8. lifting quick-change seats; 9. a quick knob; 10. leveling the bottom plate; 11. a base; 12. a lifting plate; 13. a mechanical arm; 14. a fixing frame; 15. a first liquid injection needle; 16. a second liquid injection needle; 17. a shielding box; 18. a temporary storage table; 19. a cuvette pool; 20. an infrared detection stage; 21. a first liquid storage ring; 22. a second liquid storage ring; 23. a first pipeline; 24. a second pipeline; 25. a six-way dispensing valve; 26. a current carrying liquid pool; 27. a three-way valve; 28. a syringe pump; 29. a third pipeline; 30. a fourth pipeline; 31. a fifth pipeline; 32. and a sixth pipeline.

Detailed Description

The following description of the embodiments of the present invention will be made apparent and fully in view of the accompanying drawings, in which some, but not all embodiments of the invention are shown. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

In the description of the present invention, it should be noted that the directions or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present invention and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.

In addition, the technical features of the different embodiments of the present invention described below may be combined with each other as long as they do not collide with each other.

Example 1

One embodiment of a pipetting system as shown in fig. 1-2 comprises: the shielding box 17, the accommodation space is located to shielding box 17, is equipped with lifting unit, arm 13, notes liquid subassembly, detection component in the accommodation space, and the shielding box 17 is equipped with the cleaning power subassembly outward.

As shown in fig. 1, the lifting assembly comprises a lifter 6 and a lifting plate 12, wherein the movable end of the lifter 6 is fixedly connected with the lifting plate 12. Specifically, the lifter 6 is a lifting cylinder, so as to avoid the lifter 6 having electronic components, and also realize quick replacement. As shown in fig. 1, a first liquid taking level 4 and a second liquid taking level 3 are arranged on the surface of the lifting plate 12 facing away from the lifter 6, wherein the first liquid taking level 4 is suitable for placing a sample bottle 2, the sample bottle 2 is suitable for containing radioactive liquid to be measured, and the second liquid taking level 3 is suitable for placing a sampling bottle or cuvette 1. For placing riser 6, as shown in fig. 1, still include base 11, the fixed support that is equipped with in upper surface of base 11 5, the fixed mount 14 that is equipped with in top of support 5, wherein, fixed notes liquid subassembly that is equipped with respectively on the mount 14, annotate liquid subassembly and annotate liquid needle 15 and second and annotate liquid needle 16, first notes liquid needle 15 and first liquid level 4 of getting set up correspondingly, second notes liquid needle 16 and second liquid level 3 of getting set up correspondingly. It should be noted that, the first liquid injection needle 15 and the second liquid injection needle 16 are made of stainless steel, and the end is provided with a diffusion preventing valve to prevent the overflow of the liquid to be measured after the extraction or injection is completed. As shown in fig. 1, the upper surface of the base 11 is further fixedly provided with a quick water-electricity connector 7, the quick water-electricity connector 7 is connected with the lifter 6 through a pipeline, wherein the quick water-electricity connector 7 is a clamping sleeve type direct-insertion connector with locking, a female connector of the quick water-electricity connector 7 is fixed on the base 11, a clamping position is additionally arranged on a male connector so as to facilitate the operation of the mechanical arm 13, when the quick water-electricity connector 7 breaks down, the male connector is pulled out through the mechanical arm 13, and then the lifter 6 is integrally removed out of the shielding box 17 for maintenance and replacement. As shown in fig. 1, a lifting quick-change seat 8 and a leveling base plate 10 are sequentially arranged below the base 11 towards the ground direction. As shown in fig. 1, a quick knob 9 is provided on the side of the lifting quick-change seat 8.

As shown in fig. 1, the mechanical arm 13 is disposed on a side surface of the lifting assembly, the mechanical arm 13 is provided with a mechanical claw, and the mechanical arm 13 is a multi-degree-of-freedom mechanical arm 13.

As shown in fig. 2, a detection assembly is further disposed in the accommodating space of the shielding box 17, and the detection assembly includes a temporary storage table 18, an infrared detection table 20 and a long-optical-path photometric analyzer, wherein the temporary storage table 18 is suitable for placing the sample bottle 2, the infrared detection table 20 is suitable for placing a colorimetric ware, and the long-optical-path photometric analyzer is suitable for irradiating the radioactive material liquid to be measured. It should be noted that, during the actual test, the sample bottles 2 should be placed on the temporary storage table 18 before and after the pipetting operation.

As shown in fig. 2, the cleaning power assembly includes a six-way distribution valve 25, a syringe pump 28, a three-way valve 27, and a carrier liquid tank 26, wherein the carrier liquid tank 26 is connected to the six-way distribution valve 25 through a third pipe 29, the carrier liquid tank 26 is connected to the three-way valve 27 through a fourth pipe 30, carrier liquid is contained in the carrier liquid tank 26, the three-way valve 27 is connected to the syringe pump 28 through a fifth pipe 31, and the three-way valve 27 is connected to the six-way distribution valve 25 through a sixth pipe 32. It should be noted that the injection pump 28 is composed of a stepping motor and a driver thereof, a screw rod, a bracket 5 and the like, and is used for extracting and injecting the feed liquid to be detected, the stepping motor drives the screw rod to change the rotary motion into the linear motion, the piston of the injection needle is pushed to extract and inject the feed liquid, the injection pump 28 is stable and has no pulsation, the minimum flow rate is 0.001 mu L/h, the precision is less than or equal to +/-0.5%, and the repeatability is less than or equal to +/-0.2%. The six-way distributing valve 25 is composed of a valve body, a sealing component, a cam, a valve cover and other parts, and can enable all channels of the valve body to be connected or disconnected by changing the relative position of the sealing component in the valve body, so that the reversing and starting and stopping of the carrier fluid in the pipeline are controlled. The three-way valve 27 is used for changing the flow direction of the carrier fluid, and is matched with the six-way distribution valve 25 to control the injection pump 28 to discharge the gas in the pipeline and enable the carrier fluid to fill the whole pipeline.

The device is communicated with a first liquid injection needle 15 and a second liquid injection needle 16, and further comprises a first pipeline 23 and a second pipeline 24, wherein one end of the first pipeline 23 is connected with the first liquid injection needle 15, the other end of the first pipeline is connected with a six-way distribution valve 25, and a cuvette pool 19 and a first liquid storage ring 21 are sequentially arranged from the first pipeline 23 towards the six-way distribution valve 25; one end of the second pipeline 24 is connected with the first liquid injection needle 15, the other end of the second pipeline 24 is connected with the six-way distribution valve 25, and the second pipeline 24 is also provided with a second liquid storage ring 22. It should be noted that, the first liquid storage ring 21 and the second liquid storage ring 22 are both in continuous spiral ring structures, two ends of the first liquid storage ring 21 and the second liquid storage ring 22 are communicated with the pipeline, and the first liquid storage ring 21 and the second liquid storage ring 22 are respectively used for extracting, temporarily storing and injecting the radioactive liquid to be detected. The first liquid storage ring 21 and the second liquid storage ring 22 are hard pipes made of polyether ether ketone (PEEK), the outer diameter is 1/8 inch, the inner diameter is 1/16 inch or the outer diameter is 3mm, the inner diameter is 1mm, and the liquid storage requirements of not less than 10ml are met in the first liquid storage ring 21 and the second liquid storage ring 22. In addition, the cuvette tank 19 is a plurality of continuous U-shaped pipe sections, and two ends of the cuvette tank are connected with a pipeline for measuring the ultraviolet-visible absorption spectrum of the radioactive material liquid to be measured. The U-shaped pipe section of the cuvette tank 19 adopts a hard pipe made of quartz, the outer side of the U-shaped pipe section is sprayed with Teflon polymer, the outer diameter is 1/8 inch, the inner diameter is 1/16 inch or the outer diameter is 3mm, the inner diameter is 1mm, and the length is 5-50 cm.

In order to realize automatic control, the device also comprises a controller which is respectively in communication connection with the injection pump 28, the mechanical arm 13, the lifter 6, the six-way distribution valve 25 and the three-way valve 27, and the third pipeline 29, the fourth pipeline 30, the fifth pipeline 31, the sixth pipeline 32, the injection pump 28 and the six-way distribution valve 25 are filled with carrier fluid in real time.

A method of using a pipetting system comprising the steps of:

1) The controller starts the injection pump 28 to discharge the gas in the first pipeline 23 through the six-way distribution valve 25 and the three-way valve 27, and enables the carrier liquid to fill the first pipeline 23 and be conveyed to the first liquid injection needle 15 through the first pipeline 23;

2) Starting the mechanical arm 13 to move the sample bottle 2 containing the radioactive material liquid to be detected from the temporary storage table 18 to the first liquid taking level 4 of the lifting plate 12;

3) The lifting device 6 is controlled to lift, so that the lifting plate 12 drives the sample bottle 2 to lift until the first liquid injection needle 15 is inserted into the sample bottle 2;

4) Starting an injection pump 28 and enabling the radioactive to-be-measured feed liquid in the sample bottle 2 to enter the cuvette pool 19 under the assistance of carrier liquid by means of the six-way distribution valve 25, wherein the radioactive to-be-measured feed liquid enters the first liquid storage ring 21 through the cuvette pool 19;

5) Taking the flowing cuvette cell 19 as a measuring cell, and detecting and analyzing the radioactive to-be-detected feed liquid left in the cuvette cell 19 by using a long-optical-path photometric analyzer;

6) After the ultraviolet-visible luminosity analysis is completed, the injection pump 28 is started to push back the liquid in the first pipeline 23 through the matching of the six-way distribution valve 25 and the three-way valve 27 under the assistance of the carrier liquid, so that the carrier liquid is flushed against the cuvette pool 19.

Example 2

A method of using a pipetting system comprising the steps of:

1) The controller starts the injection pump 28 to discharge the gas in the second pipeline 24 through the six-way distribution valve 25 and the three-way valve 27, and enables the carrier liquid to fill the second pipeline 24 and be conveyed to the second liquid injection needle 16 through the second pipeline 24;

2) Starting the mechanical arm 13 to move the sample bottle 2 containing the radioactive material liquid to be detected from the temporary storage table 18 to the second liquid taking level 3 of the lifting plate 12;

3) The lifting device 6 is controlled to lift, so that the lifting plate 12 drives the sample bottle 2 to lift until the second liquid injection needle 16 is inserted into the sample bottle 2;

4) Operating the injection pump 28 to pump the radioactive material liquid to be measured in the sample bottle 2 into the second liquid storage ring 22 under the assistance of the carrier liquid through the six-way distribution valve 25;

5) The lifter 6 is controlled to descend so as to separate the sample bottle 2 from the second liquid injection needle 16;

6) The mechanical arm 13 is operated to move the sample bottle 2 from the second liquid taking level 3 to the temporary storage table 18, and then the cuvette 1 is transferred to the second liquid taking level 3;

7) Pushing the lifter 6 to rise to enable the lifting plate 12 to drive the cuvette 1 to rise until the cuvette 1 is at a preset position away from the second liquid injection needle 16;

8) Operating the liquid injection pump to inject the radioactive to-be-detected liquid temporarily stored in the second liquid storage ring 22 into the cuvette device 1 by means of the six-way distribution valve 25 under the assistance of the intercepting liquid;

9) The mechanical arm 13 is operated to move the cuvette 1 to the infrared detection table 20, and near infrared detection analysis is performed through a near infrared spectrometer;

10 After near infrared detection and analysis are completed, the mechanical arm 13 is operated to pour the radioactive material liquid to be detected in the cuvette device 1;

11 The mechanical arm 13 is operated to transfer the cuvette 1 onto the second liquid taking level 3 again, the injection pump 28 is operated to inject the carrier liquid in the liquid storage ring into the cuvette 1 by means of the six-way distribution valve 25 under the assistance of the carrier liquid so as to clean the cuvette 1, and the mechanical arm 13 is operated to pour the carrier liquid in the cuvette 1.

The invention has the following advantages: (1) The liquid adding and cleaning of the two measuring station measuring pools can be realized at the same time; (2) The lifting and descending of the lifter 6 are controlled through an external pressure device or a pressure system, so that the pipetting tray and the sample bottle 2 or the cuvette positioned on the pipetting tray can be driven to ascend and descend, the first liquid injection needle 15 or the second liquid injection needle 16 can be inserted into the sample bottle 2 for extracting the liquid to be measured, the cuvette is stopped under the first liquid injection needle 15 or the second liquid injection needle 16 for a certain distance for injecting the liquid to be measured, the daily workload is greatly reduced, the operation convenience is improved, and the liquid injection needle can be accurately inserted into the sample bottle 2 or the cuvette can be accurately moved to a fixed working position under the liquid injection needle; (3) The irradiation-resistant materials such as stainless steel materials and PEEK are selected, so that the reagent adding position in the box has certain irradiation resistance, and the service life of the equipment is effectively ensured; (4) The cylinder quick-change mechanism and the cylinder quick-change knob which are convenient for the operation of the manipulator are arranged on the moving part of the lifter 6, so that the quick-wear part can be conveniently maintained and replaced in the shielding box; (5) The mechanical arm 13 is ensured to be convenient to operate, and the repeated installation and movement precision of the lifter 6 are fully ensured.

As an alternative embodiment, the lifter 6 may also be a servo motor with external power.

As an alternative embodiment, the number of U-shaped sections of cuvette cell 19 may also be 1.

It is apparent that the above examples are given by way of illustration only and are not limiting of the embodiments. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. And obvious variations or modifications thereof are contemplated as falling within the scope of the present invention.

Claims (10)

1. A pipetting system adapted for use in a highly radioactive environment comprising:

a shielding box body (17), wherein the shielding box body (17) is provided with an accommodating space;

The lifting assembly is arranged in the accommodating space and comprises a lifter (6) and a lifting plate (12), the movable end of the lifter (6) is fixedly connected with the lifting plate (12), the lifting plate (12) is suitable for placing a sample bottle (2), and the sample bottle (2) is suitable for placing radioactive feed liquid to be detected;

the liquid injection assembly comprises a liquid injection needle which is arranged in the accommodating space and corresponds to the liquid taking level;

the cuvette pool (19) is arranged in the accommodating space, and the cuvette pool (19) is connected with the liquid injection needle tube way;

the detection assembly is arranged in the accommodating space and comprises a long-optical-path photometric analyzer;

And the mechanical arm (13) is arranged in the accommodating space.

2. Pipetting system according to claim 1, wherein the lifting plate (12) is provided with a first liquid level (4), the first liquid level (4) is suitable for placing a sample bottle (2), the lifting assembly further comprises a base (11) and a fixing frame (14), a first liquid injection needle (15) is fixedly arranged on the fixing frame (14), and the first liquid injection needle (15) is arranged corresponding to the first liquid level (4).

3. Pipetting system according to claim 2, further comprising a first line (23), wherein the first line (23) is provided with a first filling needle (15), a cuvette (19) and a first reservoir (21).

4. A pipetting system according to claim 3, wherein the lifting plate (12) is provided with a second liquid level (3), the second liquid level (3) is suitable for placing a cuvette (1) or a sample bottle (2), a second liquid injection needle (16) is fixedly arranged on the fixing frame (14), and the second liquid injection needle (16) is arranged corresponding to the second liquid level (3).

5. The pipetting system according to claim 4, further comprising a second line (24), wherein a second filling needle (16) and a second reservoir ring (22) are arranged on the second line (24).

6. Pipetting system according to claim 4, wherein the detection assembly further comprises a temporary storage stage (18) and an infrared detection stage (20), the temporary storage stage (18) being adapted to place sample bottles (2), the infrared detection stage (20) being adapted to place cuvette (1).

7. Pipetting system according to claim 5, further comprising a washing power assembly arranged outside the shielding housing (17), the washing power assembly comprising a six-way dispensing valve (25), one end of the first line (23) facing away from the first filling needle (15) being connected with the six-way dispensing valve (25), one end of the second line (24) facing away from the second filling needle (16) being connected with the six-way dispensing valve (25).

8. Pipetting system according to claim 7, wherein the washing power assembly further comprises a syringe pump (28), a three-way valve (27) and a carrier liquid reservoir (26), the carrier liquid reservoir (26) being connected with the six-way dispensing valve (25) via a third line (29), the carrier liquid reservoir (26) being connected with the three-way valve (27) via a fourth line (30), the three-way valve (27) being connected with the syringe pump (28) via a fifth line (31), the three-way valve (27) being connected with the six-way dispensing valve (25) via a sixth line (32).

9. A method for using a pipetting system according to any one of claims 1-8, wherein in an operating state, the robotic arm (13) places the sample bottle (2) on the lifting plate (12), the lifting plate (12) is pushed by the lifter (6) to move towards the liquid injection needle until the liquid injection needle extends into the sample bottle (2), the liquid injection needle extracts the radioactive liquid to be measured in the sample bottle (2), the radioactive liquid to be measured flows into the cuvette (19) through the liquid injection needle, and the long-optical-path photometric analyzer irradiates the cuvette (19) to analyze the radioactive liquid to be measured in the cuvette (19).

10. Use of a pipetting system according to claim 9, comprising the steps of:

1) Starting an injection pump (28) to discharge the gas in the first pipeline (23) through a six-way distribution valve (25) and a three-way valve (27), filling the first pipeline (23) with carrier liquid, and conveying the carrier liquid to the first liquid injection needle (15) through the first pipeline (23);

2) Starting a mechanical arm (13) to move a sample bottle (2) containing the radioactive material liquid to be detected from a temporary storage table (18) to a first liquid taking level (4) of a lifting plate (12);

3) The lifting device (6) is controlled to lift, so that the lifting plate (12) drives the sample bottle (2) to lift until the first liquid injection needle (15) is inserted into the sample bottle (2);

4) Starting a syringe pump (28) and enabling the radioactive material liquid to be detected in the sample bottle (2) to enter a cuvette pool (19) with the aid of a six-way distribution valve (25), wherein the radioactive material liquid to be detected enters a first liquid storage ring (21) through the cuvette pool (19);

5) Taking the flowing cuvette cell (19) as a measuring cell, and detecting and analyzing the radioactive to-be-detected feed liquid left in the cuvette cell (19) by using a long-optical-path photometric analyzer;

6) After ultraviolet and visible luminosity analysis is completed, a syringe pump (28) is started to push back the liquid in the first pipeline (23) under the assistance of the carrier liquid through the cooperation of the six-way distribution valve (25) and the three-way valve (27), so that the carrier liquid is washed against the cuvette pool (19).