CN118058780A - Osmotic pump implantation instrument - Google Patents
Osmotic pump implantation instrument Download PDFInfo
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- CN118058780A CN118058780A CN202410473090.XA CN202410473090A CN118058780A CN 118058780 A CN118058780 A CN 118058780A CN 202410473090 A CN202410473090 A CN 202410473090A CN 118058780 A CN118058780 A CN 118058780A
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- Prior art keywords
- limiter
- inner tube
- storage part
- osmotic pump
- controller
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- 230000003204 osmotic effect Effects 0.000 title claims abstract description 60
- 238000002513 implantation Methods 0.000 title claims abstract description 25
- 238000000034 method Methods 0.000 claims description 6
- 230000035515 penetration Effects 0.000 claims 1
- 238000010171 animal model Methods 0.000 description 24
- 239000003814 drug Substances 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- 206010052428 Wound Diseases 0.000 description 4
- 230000000903 blocking effect Effects 0.000 description 4
- 239000011229 interlayer Substances 0.000 description 4
- 239000010410 layer Substances 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 206010051077 Post procedural haemorrhage Diseases 0.000 description 2
- 206010067268 Post procedural infection Diseases 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses an osmotic pump implantation instrument, which comprises; a storage part with a regular tubular structure; a puncture part positioned at one end of the storage part; the storage part is detachably connected with the puncture part; a through hole is formed in the puncture part; the power part is positioned at one end of the storage part far away from the puncture part; the power part comprises a shell, an inner tube, a controller, a pusher, a limiting device and a driving spring; the limiting device comprises a first limiter; the inner pipe is of a regular tubular structure; the outer shell is fixedly connected with the inner tube; the controller rotates between the outer shell and the inner tube; one end of the first limiter passes through the inner pipe through the inner wall of the inner pipe and then contacts the controller; the first limiter is driven by the controller to be separated from or enter the inner cavity of the inner tube; the pusher is driven by the driving spring to move along the axial direction of the inner tube.
Description
Technical Field
The invention belongs to the technical field of biological experiment instruments, and particularly relates to an osmotic pump implantation instrument.
Background
Osmotic pumps, also known as slow-release pumps, are available in volumes such as capsule size. The osmotic pump mainly comprises a semipermeable membrane, a salt interlayer and a medicine storage chamber, wherein the semipermeable membrane wraps the medicine storage chamber, and the salt interlayer is arranged between the semipermeable membrane and the medicine storage chamber. When the osmotic pump is implanted in an animal, the osmotic pressure difference between the inside and outside of the pump forces the animal body fluid to flow through the semipermeable membrane on the surface of the pump to the salt interlayer in the pump, so that the salt interlayer absorbs water and swells, and the elastic outer wall of the medicine storage chamber is extruded, so that the medicine is released through the flow guider according to the expected speed.
At present, an operation implantation mode is adopted, an experimenter manually clamps the osmotic pump to implant into an experimental animal body, the implantation operation can be completed only after a long time, an operation wound is large, the exposure time is long, the possibility of complications such as postoperative infection and bleeding is increased, and the molding rate and the death rate of the experimental animal are affected. Meanwhile, the longer operation can cause considerable stress striking to experimental animals, and the accuracy of animal behavioural experimental results is easily affected.
The present invention addresses the above-described problems by providing an osmotic pump implantation instrument.
Disclosure of Invention
In order to overcome the problems presented in the background art, the present invention provides an osmotic pump implantation instrument.
An osmotic pump implantation instrument, comprising;
A storage part with a regular tubular structure;
a puncture part positioned at one end of the storage part; the storage part is detachably connected with the puncture part; a through hole is formed in the puncture part;
The power part is positioned at one end of the storage part far away from the puncture part; the power part comprises a shell, an inner tube, a controller, a pusher, a limiting device and a driving spring; the limiting device comprises a first limiter; the inner pipe is of a regular tubular structure; the outer shell is fixedly connected with the inner tube; the controller rotates between the outer shell and the inner tube; one end of the first limiter passes through the inner pipe through the inner wall of the inner pipe and then contacts the controller; the first limiter is driven by the controller to be separated from or enter the inner cavity of the inner tube; the pusher is driven by the driving spring to move along the axial direction of the inner tube.
Further, at least two first limiters are arranged in the inner tube; the first limiters are uniformly arrayed along the axis direction of the inner tube.
Further, the limiting device further comprises a second limiter; the second limiter is fixedly arranged on the inner wall of the inner tube; the second limiter is located in the direction that the first limiter is far away from the driving spring.
Further, the first limiter is rotatably connected with the inner tube.
Further, the controller comprises a control key and a rotary sleeve, and the control key and the rotary sleeve are fixedly connected; a hollowed-out part and a guiding part are arranged in the rotary sleeve; when the hollowed-out part is aligned with the first limiter, the first limiter is separated from the inner cavity of the inner tube; in the rotating process of the controller, the guide part gradually extrudes the side part of the first limiter, so that the first limiter enters the inner cavity of the inner tube.
Further, a stop lever and a torsion spring are arranged in the storage part; the stop lever is rotationally connected with the inner wall of the storage part; the torsion spring is positioned at one end of the stop lever, which is far away from the power part; one end of the torsion spring is connected with the stop lever, and the other end of the torsion spring is connected with the inner wall of the storage part.
Further, an installation groove is formed in the storage part; the torsion spring is positioned in the mounting groove.
Further, a stop lever and a rotary sleeve are arranged in the storage part; the rotary sleeve is positioned inside the side wall of the storage part; the rotary sleeve is connected with the controller; the controller drives the rotary sleeve to rotate in the storage part; one end of the stop lever is inserted into the rotary sleeve through the inner wall of the storage part and contacts the rotary sleeve; the stop lever is driven by the rotary sleeve to be separated from or enter the internal cavity of the storage part.
Further, the bars are circumferentially arrayed inside the storage portion with the axis of the storage portion as the center.
Further, a sheath tube is arranged outside the puncture part; the sheath tube is connected with the puncture part in a sliding way.
The invention has the beneficial effects that: the puncture part is punctured into the to-be-implanted part of the experimental animal, the control key is rotated to drive the rotary sleeve to rotate, the hollowed part of the rotary sleeve is aligned with the first limiter, and at the moment, the limitation of the first limiter on the pusher is relieved; the compressed driving spring drives the pusher to move along the axial direction of the power part, so that the osmotic pump in the storage part is rapidly pushed out, the osmotic pump rapidly reaches the body of the experimental animal, the time required by implantation surgery is effectively shortened, and the stress striking degree of the experimental animal is reduced; meanwhile, the wound formed by puncture is obviously smaller than the operation implantation, the time for exposing the implantation wound of the experimental animal is shortened, the possibility of postoperative infection, bleeding and other complications is reduced, and the influence of operation on the molding rate and death rate of the experimental animal is reduced.
Drawings
FIG. 1 is a front view of an osmotic pump implantation instrument embodying the present invention in a power storage state;
FIG. 2 is a side view of an osmotic pump implantation instrument embodying the present invention in a force-accumulating state;
FIG. 3 is a cross-sectional view taken along A-A of FIG. 2;
FIG. 4 is an enlarged view of a portion of FIG. 3;
FIG. 5 is a schematic view of the installation of a stop lever embodying the present invention;
FIG. 6 is a schematic structural view of a pusher embodying the present invention;
FIG. 7 is a side view of an osmotic pump implantation instrument embodying the present invention in an ejected state;
FIG. 8 is a B-B cross-sectional view of FIG. 7;
FIG. 9 is an enlarged view of a portion of FIG. 8;
FIG. 10 is a schematic view of a rotating sleeve embodying the present invention;
FIG. 11 is a cross-sectional view of another rotary sleeve and reservoir embodying the present invention;
FIG. 12 is a schematic illustration of another coupling of a rotating sleeve to a rotating sleeve embodying the present invention;
FIG. 13 is a schematic view of another assembly of a rotating sleeve and a stop lever embodying the present invention;
In the figure, 1, a power part; 2. a storage section; 3. a puncture part; 4. an osmotic pump; 11. a control key; 12. a pusher; 13. a first stopper; 14. a second stopper; 15. a drive spring; 16. an inner tube; 17. a housing; 18. rotating the sleeve; 21. a stop lever; 22. a torsion spring; 23. a mounting groove; 24. rotating the sleeve; 31. a sheath; 121. a push rod; 122. a buffer structure; 123. a limit part; 124. a pull rod; 125. a grip portion; 181. a guiding part.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. The invention may be embodied or practiced in other different specific embodiments and features from the following examples and examples may be combined with one another without departing from the spirit or scope of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the description of the present invention, it should be understood that the directions or positional relationships indicated by the terms "center", "upper", "lower", "front", "rear", "inner", "outer", etc., are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present invention and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present invention, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
Example 1
An osmotic pump implantation instrument as shown in fig. 1-10, comprising;
a storage part 2 with a regular tubular structure;
A puncture part 3 located at one end of the storage part 2; the storage part 2 is detachably connected with the puncture part 3; the puncture part 3 is internally provided with a through hole;
A power part 1 positioned at one end of the storage part 2 far away from the puncture part 3; the power part 1 comprises a shell 17, an inner tube 16, a controller, a pusher 12, a limiting device and a driving spring 15; the limiting device comprises a first limiter 13; the inner tube 16 is of a regular tubular structure; the outer shell 17 is fixedly connected with the inner tube 16; the controller rotates between the outer shell 17 and the inner tube 16; one end of the first limiter 13 passes through the inner pipe 16 through the inner wall of the inner pipe 16 and then contacts the controller; the first limiter 13 is driven by the controller to be separated from or enter the inner cavity of the inner tube 16; the pusher 12 is moved in the axial direction of the inner tube 16 by the urging of the drive spring 15.
The power part 1 has a power storage state and an ejection state under the regulation of the controller. After compressing the driving spring 15, the controller drives the first limiter 13 into the inner cavity of the inner tube 16, and when the first limiter 13 limits the position of the pusher 12 to keep the compressed state of the driving spring 15, the power part 1 is in a power storage state. The controller is rotated, so that the first limiter 13 can be separated from the inner cavity of the inner tube 16, the power part 1 enters an ejection state, the driving spring 15 rapidly rebounds at the moment, the pusher 12 is driven to strike the osmotic pump 4, and the osmotic pump 4 enters the experimental animal body through the through hole in the puncture part 3.
Specifically, the power part 1, the storage part 2 and the puncture part 3 are connected by screw threads.
As shown in fig. 6, the pusher 12 includes a buffer structure 122, a push rod 121, a limiting portion 123, a pull rod 124, and a grip portion 125, which are sequentially disposed along an axis. The limiting portion 123 is adapted to the inner tube 16, and the first limiter 13 is capable of limiting the position of the limiting portion 123. The driving spring 15 is sleeved outside the pull rod 124. As can be seen in fig. 1-10, one end of the driving spring 15 contacts one side of the limiting portion 123 away from the push rod 121, and the other end contacts the inner side wall of the power portion 1. One end of the pull rod 124, which is far away from the limiting part 123, passes through the housing 17 and is connected with the holding part 125. Pulling the gripping portion 125 away from the housing 17, the limiting portion 123 presses the driving spring 15 and then rotates the controller, driving the first limiter 13 into the internal cavity of the inner tube 16, and the first limiter 13 limits the position of the limiting portion 123 to keep the compressed state of the driving spring 15, so that the power portion 1 enters the power storage state. When the osmotic pump 4 is required to be sprung into the experimental animal body, the controller is rotated to drive the first limiter 13 to separate from the inner cavity of the inner tube 16, the first limiter 13 does not limit the position of the limiting part 123 any more, the driving spring 15 rapidly rebounds at the moment, the buffer structure 122 is driven to impact the osmotic pump 4, and the osmotic pump 4 enters the experimental animal body through the through hole in the puncture part 3.
Specifically, the buffer structure 122 is made of soft materials such as rubber and silica gel, so as to reduce the impact force of the pusher 12 on the osmotic pump 4. The pusher 12 is prevented from directly striking on the osmotic pump 4, resulting in damage to the osmotic pump 4, thereby affecting experimental results.
At least two first limiters 13 are arranged inside the inner tube 16 for adjusting the force of the ejection osmotic pump 4; the first stoppers 13 are uniformly arrayed along the axial direction of the inner tube 16. The different first limiters 13 can fix the limiting portions 123 at different positions, so that the driving springs 15 are in different compression states, and the driving springs 15 in different compression states can provide different pushing forces.
In one embodiment of the application, a scale is provided on the pull rod 124, which is adapted to the position of the different first stop 13, and when the different scale is exposed outside the housing 17, this indicates that the stop 123 is in the vicinity of the different first stop 13. The different first limiters 13 can fix the limiting portions 123 at different positions, so that the driving springs 15 provide different pushing forces. The thrust of the driving spring 15 can be clearly controlled by the graduation.
In some embodiments of the present application, as shown in fig. 3, the first stopper 13 is disposed in mirror image in the axial direction of the inner tube 16, so that the first stopper 13 limits the position of the limiting portion 123 at two ends of the limiting portion 123, and prevents the pusher 12 from being blocked inside the inner tube 16 due to the deflection of the limiting portion 123 caused by the single-side stress of the limiting portion 123.
In some embodiments of the application, the spacing device further comprises a second spacing device 14; the second limiter 14 is fixedly arranged on the inner wall of the inner tube 16; the second stopper 14 is located in a direction in which the first stopper 13 is away from the drive spring 15. The purpose of the second stopper 14 is to: the pusher 12 is prevented from being completely separated from the power section 1 by the urging of the driving spring 15.
Specifically, the drive spring 15 is a linear compression spring.
The controller comprises a control key 11 and a rotary sleeve 18; the rotating sleeve 18 rotates between the outer shell 17 and the inner tube 16; one end of the control key 11 is connected to the swivel sleeve 18 after passing through the housing 17 outside the housing 17. The rotary sleeve 18 can be driven to move by the control key 11, so that the first limiter 13 is driven to be separated from or enter the inner cavity of the inner tube 16, and the power part 1 is in a force storage state or an ejection state.
The first stopper 13 is rotatably connected to the inner tube 16. The rotary sleeve 18 is internally provided with a hollowed-out part and a guide part 181; when the hollowed-out part is aligned with the first limiter 13, the first limiter 13 is separated from the inner cavity of the inner tube 16; during the rotation of the controller, the guide portion 181 gradually presses the side portion of the first stopper 13, so that the first stopper 13 rotates and enters the inner cavity of the inner tube 16.
An included angle smaller than 90 degrees exists between the hollowed-out part and the guide part 181, and in the process of rotating the rotary sleeve 18 to enable the first limiter 13 to enter the inner cavity of the inner tube 16, the inclined surface of the guide part 181 extrudes the corner of the first limiter 13, so that the first limiter 13 rotates towards the cavity direction of the inner tube 16.
As shown in fig. 10, each first stopper 13 is provided with a set of hollowed-out portion and a guide portion 181.
As shown in fig. 5 and 8, a stop lever 21 and a torsion spring 22 are arranged in the storage part 2; the stop lever 21 is rotatably connected with the inner wall of the storage part 2; the torsion spring 22 is positioned at one end of the stop lever 21 away from the power part 1; one end of the torsion spring 22 is connected with the stop lever 21, and the other end is connected with the inner wall of the storage part 2.
The function of the stop lever 21 is: the osmotic pump 4 is restricted to the inside of the reservoir 2. When the power part 1 is in the power storage state, the stop lever 21 limits the osmotic pump 4 in the storage part 2, so that the osmotic pump 4 is prevented from accidentally slipping, the pusher 12 cannot contact the osmotic pump 4, and the thrust of the driving spring 15 cannot be transmitted to the osmotic pump 4.
When the power part 1 enters an ejection state, the osmotic pump 4 moves in a direction away from the power part 1 under the drive of the driving spring 15, the stop lever 21 is pushed to rotate, the torsion spring 22 is pressed, and at the moment, the stop lever 21 no longer stops the osmotic pump 4.
In some examples of the application, the interior of the reservoir 2 is provided with a mounting groove 23; the torsion spring 22 is located inside the mounting groove 23. In the process of ejecting the osmotic pump 4, the stop lever 21 is stressed to rotate, the torsion spring 22 is pressed into the mounting groove 23, and at the moment, the stop lever 21 is tightly attached to the inner wall of the storage part 2, so that a movement space is provided for the osmotic pump 4.
In the specific example of the present application, the bars 21 are circumferentially arrayed inside the reservoir 2 with the axis of the reservoir 2 as the center. The plurality of blocking rods 21 simultaneously block the osmotic pump 4, and even if a single blocking rod 21 fails, the blocking effect of the blocking rod on the osmotic pump 4 is not affected.
In other embodiments of the application, an anti-slip layer is provided inside the reservoir 2; the purpose of the anti-slip layer is to prevent the osmotic pump 4 from sliding inside the reservoir 2 to define the position of the osmotic pump 4. When the power part 1 enters the ejection state, the pusher 12 pushes the osmotic pump 4 under the action of the driving spring 15, pushes the osmotic pump 4 out of the inside of the anti-slip layer, and slides the osmotic pump 4 out through the through hole of the puncture part 3 and into the body of the experimental animal.
Although the present embodiment only shows two schemes of limiting the position of the osmotic pump 4, namely, the stop lever 21 and the anti-skid layer, other schemes that can be derived by those skilled in the art based on the present embodiment to limit the osmotic pump 4 in the storage portion 2 when the power portion 1 is in the power storage state still do not depart from the spirit and scope of the present invention.
As shown in fig. 1-3, the side of the piercing section 3 remote from the storage section 2 is designed like a needle tip in order to pierce the intended implantation site of the laboratory animal.
Preferably, the sheath 31 is provided outside the puncture part 3; the sheath 31 is slidably connected to the puncture unit 3. After the puncture part 3 enters the body of the experimental animal, the sheath 31 is pushed forward to enable the sheath 31 to wrap the needle tip, so that the needle tip is prevented from stabbing viscera of the experimental animal and blunt separation can be realized. In the process of implanting the osmotic pump 4, the puncture part 3 is required to be penetrated into the to-be-implanted part of the experimental animal, then the cavity is separated from the experimental animal body by using the distal end of the puncture part 3, and then the osmotic pump 4 is ejected into the cavity in the experimental animal body. If the needle tip is adopted to separate the cavity, the tissue in the experimental animal body can be scratched due to the fact that the needle tip is sharp, the sheath tube 31 is required to wrap the needle tip to separate the cavity, the edge of the sheath tube 31 is round, and the possibility of scratching the tissue in the experimental animal body is reduced.
The application method of the embodiment comprises the following steps:
1. rotating the control key 11 to align the hollowed part of the rotary sleeve 18 with the first limiter 13;
2. Pulling the grip 125 compresses the drive spring 15;
3. Selecting proper elasticity according to the scales;
4. The control key 11 is rotated to drive the rotary sleeve 18 to rotate, and the guide part 181 drives the first limiter 13 to rotate to limit the position of the pusher 12;
5. Placing the osmotic pump 4 inside the reservoir 2;
6. The power part 1, the storage part 2 and the puncture part 3 are sequentially installed;
7. pulling the sheath 31 to expose the needle tip of the puncture part 3;
8. Penetrating the puncture part 3 into the to-be-implanted part of the experimental animal and pushing the sheath 31 to wrap the needle point;
9. The control key 11 is rotated to enable the hollowed-out part of the rotary sleeve 18 to be aligned with the first limiter 13, and the driving spring 15 drives the osmotic pump 4 to slide out of the through hole of the puncture part 3 and enter the experimental animal body;
10. The puncture part 3 is pulled out from the body of the experimental animal, and the puncture wound of the experimental animal is sutured.
Example 2
As shown in fig. 11 to 13, this embodiment is different from embodiment 1 in that:
A stop lever 21 and a rotary sleeve 24 are arranged in the storage part 2; the rotating sleeve 24 is located inside the side wall of the reservoir 2; the rotary sleeve 24 is connected with a controller; the controller drives the rotary sleeve 24 to rotate in the storage part 2; one end of the bar 21 is inserted through the inner wall of the storage part 2 and contacts the rotary sleeve 24; the bar 21 is disengaged or enters the internal cavity of the reservoir 2 under the actuation of the rotating sleeve 24.
The rotating sleeve 18 is interfitted with the rotating sleeve 24. As shown in fig. 12, a notch is provided on the end surface of the rotary sleeve 18, and a projection adapted to the notch is provided on the end surface of the rotary sleeve 24. After the power portion 1 and the storage portion 2 are screwed together, the projection is inserted into the notch, and the rotation sleeve 18 and the rotation sleeve 24 can be kept moving at the same time.
As shown in fig. 13, a second hollow portion and a second guiding portion are provided inside the rotating sleeve 24; when the second hollowed-out part is aligned with the stop lever 21, the stop lever 21 is separated from the inner cavity of the storage part 2; during the rotation of the rotating sleeve 24, the second guide gradually presses the side of the bar 21, causing the bar 21 to rotate and enter the internal cavity of the reservoir 2.
Specifically, an included angle smaller than 90 ° exists between the second hollowed-out portion and the second guiding portion, and the rotating sleeve 24 is rotated to enable the stop lever 21 to enter the internal cavity of the storage portion 2, and the inclined plane of the second guiding portion extrudes the corner of the stop lever 21, so that the stop lever 21 rotates towards the cavity direction of the storage portion 2.
Most importantly, when the hollowed-out part is aligned with the first limiter 13, the second hollowed-out part is also aligned with the stop lever 21, so that the stop lever 21 and the first limiter 13 retract simultaneously. The restriction of the pusher 12 by the first stopper 13 is released, and the restriction of the osmotic pump 4 by the stop lever 21 is released, so that the pusher 12 pushes out the osmotic pump 4 along the through hole of the puncture part 3 under the drive of the driving spring 15.
In the description of the present specification, reference to the terms "one embodiment," "some embodiments," "illustrative embodiments," "examples," "particular examples," "some examples," and the like, means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The embodiments described herein are only some, but not all, of the embodiments of the present application, and other advantages and effects of the present application will be readily apparent to those skilled in the art from the disclosure herein. The application may be embodied or applied in other specific forms and features of the following examples and examples may be combined with each other without conflict, all other examples being contemplated by those of ordinary skill in the art without undue burden from the present disclosure, based on the examples of the application.
Claims (10)
1. An osmotic pump implantation instrument, comprising;
A storage part with a regular tubular structure;
a puncture part positioned at one end of the storage part; the storage part is detachably connected with the puncture part; a through hole is formed in the puncture part;
The power part is positioned at one end of the storage part far away from the puncture part; the power part comprises a shell, an inner tube, a controller, a pusher, a limiting device and a driving spring; the limiting device comprises a first limiter; the inner pipe is of a regular tubular structure; the outer shell is fixedly connected with the inner tube; the controller rotates between the outer shell and the inner tube; one end of the first limiter passes through the inner pipe through the inner wall of the inner pipe and then contacts the controller; the first limiter is driven by the controller to be separated from or enter the inner cavity of the inner tube; the pusher is driven by the driving spring to move along the axial direction of the inner tube.
2. The apparatus according to claim 1, wherein the inner tube is provided with at least two first stoppers inside; the first limiters are uniformly arrayed along the axis direction of the inner tube.
3. The osmotic pump implantation instrument according to claim 1, wherein said stop apparatus further comprises a second stop; the second limiter is fixedly arranged on the inner wall of the inner tube; the second limiter is located in the direction that the first limiter is far away from the driving spring.
4. The osmotic pump implantation instrument according to claim 1, wherein said first limiter is rotatably coupled to said inner tube.
5. The osmotic pump implantation instrument according to claim 4, wherein said controller comprises a control key and a rotating sleeve fixedly connected to each other; a hollowed-out part and a guiding part are arranged in the rotary sleeve; when the hollowed-out part is aligned with the first limiter, the first limiter is separated from the inner cavity of the inner tube; in the rotating process of the controller, the guide part gradually extrudes the side part of the first limiter, so that the first limiter enters the inner cavity of the inner tube.
6. The osmotic pump implantation instrument according to claim 1, wherein a stop lever and a torsion spring are arranged in the storage part; the stop lever is rotationally connected with the inner wall of the storage part; the torsion spring is positioned at one end of the stop lever, which is far away from the power part; one end of the torsion spring is connected with the stop lever, and the other end of the torsion spring is connected with the inner wall of the storage part.
7. The apparatus according to claim 6, wherein the storage part is internally provided with a mounting groove; the torsion spring is positioned in the mounting groove.
8. The osmotic pump implantation instrument according to claim 1, wherein a stop lever and a rotary sleeve are arranged in the storage part; the rotary sleeve is positioned inside the side wall of the storage part; the rotary sleeve is connected with the controller; the controller drives the rotary sleeve to rotate in the storage part; one end of the stop lever is inserted into the rotary sleeve through the inner wall of the storage part and contacts the rotary sleeve; the stop lever is driven by the rotary sleeve to be separated from or enter the internal cavity of the storage part.
9. An osmotic pump implantation instrument according to any of claims 6 to 8, wherein the bars are circumferentially arrayed inside the reservoir centered on the axis of the reservoir.
10. An osmotic pump implantation instrument according to any one of claims 1 to 8, wherein a sheath is provided outside the penetration portion; the sheath tube is connected with the puncture part in a sliding way.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410473090.XA CN118058780A (en) | 2024-04-19 | 2024-04-19 | Osmotic pump implantation instrument |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202410473090.XA CN118058780A (en) | 2024-04-19 | 2024-04-19 | Osmotic pump implantation instrument |
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| CN118058780A true CN118058780A (en) | 2024-05-24 |
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| CN202410473090.XA Pending CN118058780A (en) | 2024-04-19 | 2024-04-19 | Osmotic pump implantation instrument |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5874098A (en) * | 1997-05-28 | 1999-02-23 | Ivy Laboratories, Inc. | Pellet implant system |
| US20020111603A1 (en) * | 1996-12-02 | 2002-08-15 | Societe De Conseils De Recherches Et D'application | Device for local administration of solid or semi-solid formulations and delayed-release formulations for proposal parental administration and preparation process |
| US20020188301A1 (en) * | 2001-06-11 | 2002-12-12 | Dallara Mark Douglas | Tissue anchor insertion system |
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| US20170136224A1 (en) * | 2015-01-26 | 2017-05-18 | Nano Precision Medical, Inc. | Apparatus and Method for Promoting Fluid Uptake Into an Implant |
| CN213285296U (en) * | 2020-06-05 | 2021-05-28 | 李毛才 | Needle is implanted to active particle |
| CN213899572U (en) * | 2020-11-26 | 2021-08-06 | 威克斯特（宜昌）机械有限公司 | Connect tight motor interface structure |
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2024
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|---|---|---|---|---|
| US20020111603A1 (en) * | 1996-12-02 | 2002-08-15 | Societe De Conseils De Recherches Et D'application | Device for local administration of solid or semi-solid formulations and delayed-release formulations for proposal parental administration and preparation process |
| US5874098A (en) * | 1997-05-28 | 1999-02-23 | Ivy Laboratories, Inc. | Pellet implant system |
| US20020188301A1 (en) * | 2001-06-11 | 2002-12-12 | Dallara Mark Douglas | Tissue anchor insertion system |
| US20030233101A1 (en) * | 2002-06-17 | 2003-12-18 | Senorx, Inc. | Plugged tip delivery tube for marker placement |
| US20070173706A1 (en) * | 2005-11-11 | 2007-07-26 | Isense Corporation | Method and apparatus for insertion of a sensor |
| CN101304697A (en) * | 2005-11-11 | 2008-11-12 | 爱森斯有限公司 | Method and apparatus for insertion of a sensor |
| US20170136224A1 (en) * | 2015-01-26 | 2017-05-18 | Nano Precision Medical, Inc. | Apparatus and Method for Promoting Fluid Uptake Into an Implant |
| CN213285296U (en) * | 2020-06-05 | 2021-05-28 | 李毛才 | Needle is implanted to active particle |
| CN213899572U (en) * | 2020-11-26 | 2021-08-06 | 威克斯特（宜昌）机械有限公司 | Connect tight motor interface structure |
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