CN1180536A - Chinese gromwell seed oil soft capsule - Google Patents
Chinese gromwell seed oil soft capsule Download PDFInfo
- Publication number
- CN1180536A CN1180536A CN 96119487 CN96119487A CN1180536A CN 1180536 A CN1180536 A CN 1180536A CN 96119487 CN96119487 CN 96119487 CN 96119487 A CN96119487 A CN 96119487A CN 1180536 A CN1180536 A CN 1180536A
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- China
- Prior art keywords
- acid
- soft capsule
- seed oil
- seed
- linolenic
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Abstract
A soft capsule of purple gromwell seed oil contains such components (Wt.%) as palmic acid (4.8-5.2), stearic acid (2.1-2.6), oleic acid (11.4-12.7), VE1, linoleic acid (20-20.7), gamma-linolenic acid (13.7-14.1), alpha-linolenic acid (30-31.9), parinaric acid (12.7-13.7), eicosenoic acid (1.0-1.3) and water (rest).
Description
The present invention relates to Chinese gromwell seed oil soft capsule.
According to bibliographical information, the r-linolenic acid can guarantee the homergy of prostaglandin, and have the effect of tangible hypercholesterolemia reducing, have blood pressure lowering, anticoagulant, antioxidation, treatment diabetes concurrently, suppress gastrorrhagia, fat-reducing, treatment dermatosis, to effects such as anti-liver injury, nonspecific infections.Alpha-linolenic acid has effects such as antithrombotic, blood pressure lowering, blood fat, cholesterol, antitumor, inhibition allergy.Research worker has been made extensive work at Radix Oenotherae erythrosepalae oil and CHAISU oil in recent years.The present patent application people has proposed " extracting greasy method from arnabia seed " application for a patent for invention July 20 nineteen ninety-five, application number is No. 95111886.2, this method comprises with fat-soluble organic solvent removes the surface of the seed waxiness, pulverizing, defibrination, solvent extraction, solid-liquid separation, separation solvent, refining, must make with extra care seed oil.Yet, realize commercial approach as seed oil, no matter be as food, medicine or other commercial Application, need be support all, and know the active ingredient of these commodity with physicochemical data accurately.
The purpose of this invention is to provide the Chinese gromwell seed oil soft capsule of determining composition.
The objective of the invention is to adopt following technical scheme to be achieved:
The weight percentage of the relevant composition that the soft capsule that obtains wraps up:
Hexadecanoic acid (Palmic acid) 4.8-5.2
Octadecanoic acid (stearic acid) 2.1-2.6
18 carbon-olefin(e) acid (oleic acid) 11.4-12.7
Vitamin E 1
Linoleic acid 20-20.7
R-linolenic acid 13.7-14.1
Alpha-linolenic acid 30-31.9
Parinaric acid 12.7-13.7
20 carbon-olefin(e) acid 1.0-1.3
Vitamin E in the above-mentioned composition adds for metering.
Surplus is a water.
The extracting method of Chinese gromwell seed oil has multiple in the soft capsule of the present invention, but be not destroyed in order to ensure the active ingredient in this seed oil, preferred extracting method is solvent extraction method or carbon dioxide supercritical fluid extraction method, in these two kinds of methods, to remove the waxiness of kind of subshell in advance, be best with solvent extraction or carbon dioxide supercritical fluid extraction then.
Below in conjunction with embodiment in detail the present invention is described in detail:
The percentage composition of the relevant composition that the soft capsule that obtains wraps up is:
Hexadecanoic acid (Palmic acid) 4.8-5.2
Octadecanoic acid (stearic acid) 2.1-2.6
18 carbon-olefin(e) acid (oleic acid) 11.4-12.7
Vitamin E 1
Linoleic acid 20-20.7
R-linolenic acid 13.7-14.1
Alpha-linolenic acid 30-31.9
Parinaric acid 12.7-13.7
20 carbon-olefin(e) acid 1.0-1.3
Surplus is a water.
The fluctuation of content system is by factor decisions such as the difference of every batch of seed, collecting times in the above-mentioned composition, yet as there being the linolenic vegetable oil mixt of alpha-linolenic acid and r-simultaneously, the potential application of the present invention is very widely.
The selected oils and fats extracting method of present embodiment promptly can be No. 95111886.2 methods in first to file, also can be remove in advance kind of sublist to waxiness, use the carbon dioxide supercritical fluid extraction method then, existing illustrated respectively;
Extracting method A: form by following processing step:
(1) except that cured
Select fat-soluble organic solvent, by per 100 parts of seed solubilizer 200-400 parts, fully stir in 20-40 ℃, the cured matter of flush away the surface of the seed is filtered, and solution is through the cured matter of refrigerated separation, and for recycling, it is 4-6% that the control seed contains warm rate;
(2) pulverizing, defibrination
To be broken to the 80-100 order except that the seed meal after cured, 40-60 ℃ adds the water mill slurry, and the water addition ratio example adds water 200-300 part for per 100 parts of seeds (raw material), and defibrination to material is suspended state;
(3) solvent extraction
Select and the identical organic solvent of (1) step, in hermetic container,, in hermetic container, blast nitrogen, displace wherein air, stirred 30-45 minute, leave standstill by adding 150-200 part organic solvent in the suspension after per 100 parts of seed treatment.
(4) solid, liquid separates
Make solid-liquid separation with centrifuge, obtaining liquid is left standstill, tell lower floor's water, get the oil phase mixed liquor.
(5) separate solvent
With obtaining oil phase reclaim under reduced pressure organic solvent under 70-80 ℃/50-60mmHg condition, get slightly oil;
(6) refining
With the active carbon mixed solution dipping oven dry after 4 hours that contains 5%NaOH and 5% sodium citrate, by per 100 parts of slightly oily active carbon 2-3 parts that add after handling, fully stir 30 parts of clocks, filter, oil phase gets refined oil through being washed to neutrality.
Described fat-soluble organic solvent is selected at least a in normal hexane, petroleum ether, acetone, dichloroethanes, the 120# rubber solvent naphtha.
The oil yield of said method 〉=16%.
Extracting method B:
Select fat-soluble organic solvent to remove arnabia seed surface waxiness, be specially per 100 parts of seed stuffing solubleness organic solvent 20-30 parts, fully stir after-filtration, containing wet seed washes with water, filter, seed is blown to containing warm rate less than 20%, with the oils and fats in the carbon dioxide supercritical fluid extraction seed, oil yield 〉=17% with air.
The processing technology of soft capsule of the present invention (soft gelatin capsule) is identical with the processing technology of vitamin E soft gelatin capsule, does not give unnecessary details at this.
Claims (1)
1. Chinese gromwell seed oil soft capsule, it is characterized in that: the weight percentage of the relevant composition that soft capsule wrapped up is:
Hexadecanoic acid (Palmic acid) 4.8-5.2
Octadecanoic acid (stearic acid) 2.1-2.6
18 carbon-olefin(e) acid (oleic acid) 11.4-12.7
Vitamin E 1
Linoleic acid 20-20.7
R-linolenic acid 13.7-14.1
Alpha-linolenic acid 30-31.9
Parinaric acid 12.7-13.7
20 carbon-olefin(e) acid 1.0-1.3
Surplus is a water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96119487 CN1180536A (en) | 1996-10-17 | 1996-10-17 | Chinese gromwell seed oil soft capsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96119487 CN1180536A (en) | 1996-10-17 | 1996-10-17 | Chinese gromwell seed oil soft capsule |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1180536A true CN1180536A (en) | 1998-05-06 |
Family
ID=5125739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96119487 Pending CN1180536A (en) | 1996-10-17 | 1996-10-17 | Chinese gromwell seed oil soft capsule |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1180536A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1100860C (en) * | 1999-11-29 | 2003-02-05 | 徐淑梅 | Puccoon seed oil and its extraction method |
| CN100425146C (en) * | 1999-03-10 | 2008-10-15 | 株式会社盛多利 | Higher unsaturated fatty acid composition |
-
1996
- 1996-10-17 CN CN 96119487 patent/CN1180536A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100425146C (en) * | 1999-03-10 | 2008-10-15 | 株式会社盛多利 | Higher unsaturated fatty acid composition |
| CN1100860C (en) * | 1999-11-29 | 2003-02-05 | 徐淑梅 | Puccoon seed oil and its extraction method |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |