CN1180523A - Compound hemorrhoids necrotized oil for treating anal and intestinal disease and its preparation method - Google Patents

Abstract

A compound ointment for treating anorectal diseases such as internal hemorrhoid, fissure in ano, rectum prolapse, rectal polyp and mixed hemorrhoid is prepared from aluminium potassium sulfate, sodium chloride, sterilizing water, Tween-80, phenol, medicinal glycerine and procaine powder through dissolving, mixing, high-pressure sterilization, and bottling, and features high and durable curative effect, low dosage, and less by-effect.

Description

Be used for the treatment of compound hemorrhoids necrotized oil of anal and intestinal disease and preparation method thereof

The present invention relates to a kind of compound method that is used for the treatment of the medicinal liquid and the medicinal liquid of anal and intestinal disease.

Anal and intestinal disease has suitable universality in human illness, but, in the prior art for this class disease, no matter be excision, ligation, injection for curing, or utilize Kuzhi San, withered hemorrhoid tincture, anus to treat with methods such as ointment, bolt, thermal therapeutic apparatus, electronic therapeutic instruments, all ubiquity late result instability, medical treatment cost height.The part Therapeutic Method can cause complication such as anal incontinence, anal stenosis, anus distortion, edema, inflammation.And treatment cycle is long.

The objective of the invention is to avoid above-mentioned weak point of the prior art, a kind of anal and intestinal disease that is used for the treatment of is provided, its curative effect height, the compound hemorrhoids necrotized oil that treatment cycle is short, medical treatment cost is low.The objective of the invention is to provide simultaneously the manufacture method of this medicinal liquid.

Purpose of the present invention is achieved through the following technical solutions.

The compound hemorrhoids necrotized oil that is used for the treatment of anal and intestinal disease is characterized in that having each component of following content:

Aluminium potassium sulfate 4～40 gram sodium chloride (NaCl) 16～160 grams

Sterilization water 20～200ml tween 80 4～40ml

Phenol 1～10ml medicinal glycerin 100～1000ml

Procaine powder 1～10 gram.

Manufacture method of the present invention has following each step:

(1), dissolve into aqueous with sodium chloride (NaCl) with the heating of sterilization water aluminium potassium sulfate;

(2), the glycerol that will be heated to 90 ℃ mixes with step (1) gained medicinal liquid, jolting is even;

(3), when treating above-mentioned steps (2) gained medicinal liquid temperature drop to 60 ℃, add tween 80, jolting is even;

(4), when treating above-mentioned steps (3) gained medicinal liquid temperature drop to 40 ℃, add phenol and procaine powder, shaking casts to dissolving fully;

(5), above-mentioned steps (4) gained medicinal liquid, takes out branch and is filled in the 2ml bottle after 45 minutes through autoclaving.

Indication of the present invention comprises each phase internal hemorrhoid, rectal polyp, anal fissure, proctoptosis, mixed hemorrhoid internal hemorrhoid part.Simultaneously, effective too for nasal polyp, uterine prolapse, hemangioma, subcutaneous cyst, cicatrix tuberosity etc.It cures mainly function is astringing to arrest bleeding, blocks haemorrhoidal vein, makes microcirculation stop blood supply, forms aseptic inflammation, makes the withered voluntarily necrosis of blood stasis come off and obtain entirely and heals.

Can go up the curative effect determinate standard scheme of formulation according to national anorectal in 1987, the present invention is in the 11593 routine process of clinical application in 25 years, except that 55 examples are invalid, 18 examples are not followed the doctor's advice because for the treatment of the back patient, being engaged in physical work work and strenuous exercise too early causes vein blood vessel to break, cause that outside the complication such as massive hemorrhage, all the other cases all obtain complete, none example meets accident thing and causes death.Do not see a routine sequela yet.

Practice shows, that compound hemorrhoids necrotized oil of the present invention has is evident in efficacy, easy to use, simple to operate, safe and reliable to anal and intestinal diseases such as all types of internal hemorrhoid, anal fissure, proctoptosis, rectal polyp, mixed hemorrhoid internal hemorrhoid parts, dosage is little, cost is low, have no side effect, old man and all applicable advantage of infant.Treatment no obvious pain in back and sense of discomfort.Late result is reliable and stable, and relapse rate is low, and medical care expenses is few, is accepted by the patient easily.Be not subjected to any condition restriction during use.All can execute art safely in outpatient service, in-patient department, commune hospital, clinic, patient family.Postoperative is had a rest and can all be recovered normal later in three hours.Do not influence patient's daily life and general non-manual work work.

The present invention compared with the prior art, its consumption is little, few side effects, late result are stable lasting.Operational approach is easy, and medical expense is low, and therapeutic effect is good.

By the following examples the present invention is further described.

Embodiment 1:

Get aluminium potassium sulfate 20 gram sodium chloride 80 grams

Sterilization water 100ml tween 80 20ml

Phenol 5ml medicinal glycerin 400ml

Procaine powder 5 grams.

Manufacturing process is as follows:

(1), dissolve into aqueous with sodium chloride with the heating of sterilization water aluminium potassium sulfate;

(2), the glycerol that will be heated to 90 ℃ mixes with step (1) gained medicinal liquid, jolting is even;

(3), when treating above-mentioned steps (2) gained medicinal liquid temperature drop to 60 ℃, add tween 80, shake and broadcast evenly;

(4), when treating above-mentioned steps (3) gained medicinal liquid temperature drop to 40 ℃, add phenol and procaine powder, jolting is to dissolving fully;

(5), above-mentioned steps (4) gained medicinal liquid, takes out branch and is filled in the 2ml bottle after 45 minutes through autoclaving.Under the room temperature, preserve and do not affect the treatment in 5 years.

Embodiment 2:

Get aluminium potassium sulfate 40 gram sodium chloride 160 grams

Sterilization water 200ml tween 80 40ml

Phenol 10ml medicinal glycerin 800ml

Procaine powder 10 grams.

Manufacturing process such as embodiment 1.

Embodiment 3:

Get aluminium potassium sulfate 4 gram sodium chloride 16 grams

Sterilization water 20ml tween 80 4ml

Phenol 1ml medicinal glycerin 100ml

Procaine powder 1 gram.

Manufacturing process is with embodiment 1.

Operational approach: advise patient's emptying defecation before the art, the routine disinfection operating field, the anal canal internal hemorrhoid injection zone of tightly sterilizing, the lid aseptic hole-towel fully exposes blood stasis under local anaesthesia, directly medicinal liquid is injected blood stasis tela submucosa.Make blood stasis become canescence by aubergine.According to the blood stasis size, each blood stasis injection 0.5ml, big and many person can inject in batches as blood stasis.A total amount is no more than 6ml and is advisable.Pin hole is pushed with cotton balls in the injection back, gently rubs to make the pin hole closure a moment, and medicinal liquid is evenly distributed.As blood stasis take off outward, mucosa turns up, anus edema person, immediately blood stasis and ectopia cloacae mucosa is pushed into anal after the injection, injects Rhizoma Coptidis extractum or jiuhua plaster, antiphlogistine and so on, lid is with the turriform gauze, with T bandage or immobilization with adhesive tape.

Points for attention: sterilization must be tight before the operation, and inspection must be conscientiously careful, and diagnosis must accurately be grasped indication, contraindication.Postoperative advises the patient to forbid to be engaged in heavy physical labour and strenuous exercise in three weeks.The pungent irritable food of fasting.And note maintenance defecation every day once, prevent to be hard and dry.The married avoids sexual life.

Model case 1:

Li Xianying, suffered from inside and outside mixed hemorrhoid 45 years at women .72 year.Once hospitalization repeatedly, underwent operative, also through all recoveries from illness of injection treatment, laser therapy.Patient's condition development in 1980 is serious, and blood stasis and mucosa prolapse entirely, the anus incarceration, and serious edema can not Hui Na.Adopt the present invention to treat, the four stars phase more leaves hospital entirely, has been close on ninety-year-old so far, and is healthy, cures and never suffers from 15 years again.

Case 2:

Tian Dongsheng. the man, 9 years old, back 6 months trouble chronic enteritiss of being born cause proctoptosis, and were invalid through multi-treatment, and serious further.To in March, 81, the infant mucous membrane of rectum prolapses entirely, weighs three degree, and edema did not reset in seven days, and is agonizing, and through treating with the present invention, three times complete, 15 years so far, follows up a case by regular visits to never ill again.

Case 3:

Gao Lan, the woman, 45 years old, once repeatedly operation not more not and cause the sequela of anal stenosis, dyschesia, the twin property of anus convulsion pain continues 10 hours after an action of the bowels, can't bear to stand.Adopted the present invention to treat in 1979 complete, and 16 years so far, follow up a case by regular visits to the patient and react gun-ho, it is normal all the time to defecate.

Case 4:

Jiang Jicheng, the man 8 years old, suffered from multiple rectal polyp 5 years, the Ceng Sanci surgical removal.The back time is not long, than more before not controlling, adopts compound hemorrhoids necrotized oil root injection treatment of the present invention in 82 years, and a week heals entirely, does not see recurrence in 13 years to following up a case by regular visits to.

Contraindication of the present invention comprises: acute hemorrhagic disease, thrombocytopenia, acute chronic enteritis, bacillary dysentery, heart attack phase, liver, renal function grievous injury person, pulmonary tuberculosis are sent out phase, anemia of pregnant woman just before giving birth phase, fibrosis internal hemorrhoid.

Claims (2)

1, a kind of compound hemorrhoids necrotized oil that is used for the treatment of anal and intestinal disease is characterized in that having each component of following content:

Aluminium potassium sulfate 4～40 gram sodium chloride (NaCl) 16～160 grams

Sterilization water 20～200ml tween 80 4～40ml

Phenol 1～10ml medicinal glycerin 100～1000ml

Procaine powder 1～10 gram.

2, the manufacture method of the described compound hemorrhoids necrotized oil of a kind of claim 1 is characterized in that having following each step:

(1), dissolve into aqueous with sodium chloride (NaCl) with the heating of sterilization water aluminium potassium sulfate;

(2), the glycerol that will be heated to 90 ℃ mixes with step (1) gained medicinal liquid, jolting is even;

(3), when treating above-mentioned steps (2) gained medicinal liquid temperature drop to 60 ℃, add tween 80, jolting is even;

(4), when treating above-mentioned steps (3) gained medicinal liquid temperature drop to 40 ℃, add phenol and procaine powder, jolting is to dissolving fully;

(5), above-mentioned steps (4) gained medicinal liquid, takes out branch and is filled in the 2ml bottle after 45 minutes through autoclaving.