CN117999030A - Oxygen saturation estimation system for detecting ring by using PPG signal - Google Patents
Oxygen saturation estimation system for detecting ring by using PPG signal Download PDFInfo
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 126
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 126
- 239000001301 oxygen Substances 0.000 title claims abstract description 126
- 238000001514 detection method Methods 0.000 claims abstract description 42
- 238000006243 chemical reaction Methods 0.000 claims abstract description 14
- 238000013186 photoplethysmography Methods 0.000 claims abstract description 10
- 230000001133 acceleration Effects 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 22
- 238000004364 calculation method Methods 0.000 claims description 6
- 238000005259 measurement Methods 0.000 description 26
- 238000007781 pre-processing Methods 0.000 description 8
- 238000013527 convolutional neural network Methods 0.000 description 4
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- 238000005516 engineering process Methods 0.000 description 4
- 238000010606 normalization Methods 0.000 description 4
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 206010021143 Hypoxia Diseases 0.000 description 2
- 238000013528 artificial neural network Methods 0.000 description 2
- 239000004020 conductor Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
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- 230000006403 short-term memory Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 1
- 238000010292 electrical insulation Methods 0.000 description 1
- 208000018875 hypoxemia Diseases 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 238000012417 linear regression Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
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Abstract
The present invention provides an oxygen saturation estimation system for detecting a ring using a photoplethysmography (Photoplethysmography, PPG) signal. The system includes a server, the server including: a signal quality classification component for classifying the quality of the first wavelength PPG signal and the second wavelength PPG signal as good or bad; and an oxygen saturation estimating component for estimating oxygen saturation from the first and second wavelength PPG signals, wherein the PPG signal detection ring comprises a plurality of sensors located at different positions, each of the plurality of sensors configured to measure the first and second wavelength PPG signals, each of the plurality of sensors comprising a first wavelength light source, a second wavelength light source and a photoelectric conversion device, the terminal may comprise a sensor selecting component configured to select, among the plurality of sensors, a sensor that measures a combination of a first and second wavelength test PPG signal of highest signal quality among the plurality of first and second wavelength test PPG signals as the sensor for measuring the first and second wavelength PPG signals.
Description
Technical Field
The present disclosure relates to an oxygen saturation estimation system. And more particularly to an oxygen saturation estimation system that uses PPG (Photoplethysmography ) signals to detect a ring.
Background
Oxygen saturation means the ratio of hemoglobin saturated by oxygen bound in the body to total hemoglobin in the body. Typically, the value is 95% to 100%, and if it is less than or equal to 90%, it is called hypoxia (hypoxemia), and if it is less than or equal to 80%, the tissues of the body are severely damaged. Therefore, there is a need for a method of easily measuring oxygen saturation to check health conditions in daily life without going to a hospital.
Disclosure of Invention
Technical problem
The problem addressed by the present disclosure is to provide an oxygen saturation estimation system for detecting a ring using photoplethysmography (Photoplethysmography, PPG signal).
Technical proposal
To solve the above-described problems, an oxygen saturation estimation system for detecting a ring using a PPG signal according to an embodiment of the present disclosure includes a server including: a signal quality classification component for classifying the quality of the first wavelength PPG signal and the second wavelength PPG signal as good or bad; and an oxygen saturation estimating component for estimating oxygen saturation from the first and second wavelength PPG signals, wherein the first and second wavelength PPG signals are measured using the PPG signal detection ring, the server receives the first and second wavelength PPG signals from the PPG signal detection ring through a terminal, the PPG signal detection ring comprising a plurality of sensors located at different locations, each of the plurality of sensors for measuring the first and second wavelength PPG signals, each of the plurality of sensors comprising a first wavelength light source, a second wavelength light source, and a photoelectric conversion device, the terminal may comprise a sensor selecting component for selecting, as the PPG sensor for measuring the first and second wavelength PPG signals, a combination of the first and second wavelength test signals having the highest signal quality among the plurality of first and second wavelength test signals.
In some embodiments, the signal quality of the plurality of test PPG signals may be assessed by at least one of an acceleration signal magnitude, a signal-to-noise ratio, and an AC component magnitude to DC component magnitude ratio.
In some embodiments, the server may further comprise an oxygen saturation index calculation component for calculating an oxygen saturation index, the oxygen saturation index being defined as a ratio of a time when the signal quality classification component classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good and the oxygen saturation deviates from a normal range to a time when the signal quality classification component classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good.
In some embodiments, the terminal may further comprise a light source control component for controlling the first wavelength light source and the second wavelength light source of each of the plurality of sensors such that a DC component of each of the plurality of first wavelength test PPG signals measured using the plurality of sensors, respectively, is within a first predetermined range and a DC component of each of the plurality of second wavelength test PPG signals measured using the plurality of sensors, respectively, is within a second predetermined range.
In some embodiments, the controlling of the first wavelength light source and the second wavelength light source by the light source control component and the selecting of the sensor by the sensor selection component may be performed sequentially, and the controlling of the first wavelength light source and the second wavelength light source by the light source control component and the selecting of the sensor by the sensor selection component may be performed periodically.
An oxygen saturation estimation method for detecting a ring using a PPG signal according to an embodiment of the present disclosure includes: receiving, by a terminal, a first wavelength PPG signal and a second wavelength PPG signal from a PPG signal detection ring; classifying the quality of the first wavelength PPG signal and the second wavelength PPG signal as good or bad; and estimating oxygen saturation from the first and second wavelength PPG signals, wherein the PPG signal detection ring comprises a plurality of sensors located at different locations, each of the plurality of sensors for measuring the first and second wavelength PPG signals, each of the plurality of sensors comprising a first wavelength light source, a second wavelength light source and a photoelectric conversion device, the terminal may comprise a sensor selection component for selecting, among the plurality of sensors, the sensor that measures a combination of the first and second wavelength test PPG signals of highest signal quality among the plurality of first and second wavelength test PPG signals as the sensor for measuring the first and second wavelength PPG signals.
In some embodiments, the signal quality of the plurality of test PPG signals may be assessed by at least one of an acceleration signal magnitude, a signal-to-noise ratio, and an AC component magnitude to DC component magnitude ratio.
In some embodiments, the method further comprises: an oxygen saturation index is calculated, wherein the oxygen saturation index may be defined as a ratio of a time when the signal quality classification component classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good and the oxygen saturation deviates from a normal range to a time when the signal quality classification component classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good.
In some embodiments, the terminal may further comprise a light source control component for controlling the first wavelength light source and the second wavelength light source of each of the plurality of sensors such that a DC component of each of the plurality of first wavelength test PPG signals measured using the plurality of sensors, respectively, is within a first predetermined range and a DC component of each of the plurality of second wavelength test PPG signals measured using the plurality of sensors, respectively, is within a second predetermined range.
In some embodiments, the controlling of the first wavelength light source and the second wavelength light source by the light source control component and the selecting of the sensor by the sensor selection component may be performed sequentially, and the controlling of the first wavelength light source and the second wavelength light source by the light source control component and the selecting of the sensor by the sensor selection component may be performed periodically.
Advantageous effects
The present invention provides an oxygen saturation estimation system that uses a PPG signal to detect a ring. According to the present invention, oxygen saturation can be continuously and easily monitored in daily life. According to the invention, the PPG signal detection ring may comprise a plurality of sensors located at different positions. Among the plurality of sensors, a sensor having excellent signal quality of the first wavelength PPG signal and the second wavelength PPG signal may be selected. Thus, a sensor may be selected that is adapted to the different vessel positions and shapes of each user.
Drawings
Fig. 1 is a perspective view of a photoplethysmography (Photoplethysmograph, PPG) signal detection ring according to one embodiment of the present invention.
Fig. 2 is an exploded perspective view of a PPG signal detection ring according to an embodiment of the present invention.
Fig. 3 is a block diagram of an oxygen saturation estimation system for detecting a ring using PPG signals according to an embodiment of the present invention.
Fig. 4 is a flow chart of a method of oxygen saturation estimation for detecting a ring using a PPG signal.
Fig. 5 is a flowchart of a method of setting up a sensor for PPG signal detection of a ring.
Detailed Description
Fig. 1 is a perspective view of a photoplethysmography (Photoplethysmography, PPG) signal detection ring (100) according to one embodiment of the present invention. Fig. 2 is an exploded perspective view of a PPG signal detection ring (100) according to an embodiment of the present invention.
Referring to fig. 1 and 2, the ppg signal detection ring (100) may include an external electrode (130), an internal electrode (140), an insulation unit (150), a top cover (110), an operation display unit (120), and a plurality of sensors (160).
The external electrode (130) may have an arc shape. The external electrode (130) may be made of a conductor and may be used as an electrode for measuring an Electrocardiogram (ECG). In addition, the external electrode (130) may form the appearance of the PPG signal detection ring (100), and the external electrode (130) may be in contact with the body of the user.
The inner electrode (140) may be annular in shape and may have a plurality of openings (145) for a plurality of sensors (160). The internal electrode (140) may be made of a conductor and may be used as an electrode for measuring an electrocardiogram. In addition, the internal electrode (140) may form an internal view of the PPG signal detection ring (100), and the internal electrode (140) may be in contact with a finger of the user.
The insulating unit (150) may be disposed between the external electrode (130) and the internal electrode (140). The insulating unit (150) may realize electrical insulation between the external electrode (130) and the internal electrode (140).
The top cover (110) may have an arc shape and may form a ring shape together with the external electrode (130). The cap (110) may form the appearance of the PPG signal detection ring (100).
The operation display unit (120) may be combined with the top cover (110). The operation display unit (120) may include a plurality of Light Emitting Diodes (LEDs), such as green LEDs and red LEDs. The operation display unit (120) may display an operation of the PPG signal detection ring (100) using a plurality of LEDs. For example, a green LED may be lit for 2 seconds to indicate the start of the measurement, a green LED may be lit for 1 second to indicate the end of the measurement (e.g., a green LED may be turned on for two seconds to indicate the start of the measurement, and a green LED may be turned on for one second to indicate the end of the measurement). In addition, the red LED may be repeatedly turned on and off at 1 second period to notify of the failure.
A plurality of sensors (160) may be in contact with a user's finger. The plurality of sensors (160) may each be located within the plurality of openings (145) of the inner electrode (140) and may protrude from a surface of the inner electrode (140). The plurality of sensors (160) may be configured to acquire different pluralities of first wavelength PPG signals and second wavelength PPG signals at different locations. Each sensor (160) may include first and second wavelength light sources of different wavelengths and a photoelectric conversion device.
In some embodiments, although not shown in fig. 1 and 2, the PPG signal detection ring (100) may further include an acceleration sensor disposed between the outer electrode (130) and the inner electrode (140).
Fig. 3 is a block diagram of an oxygen saturation estimation system (1000) for detecting a ring using PPG signals according to an embodiment of the present invention.
Referring to fig. 3, an oxygen saturation estimation system (1000) using a PPG signal detection ring may include a PPG signal detection ring (100), a first terminal (200), a server (300), and a second terminal (400).
The PPG signal detection ring (100) may include a plurality of sensors, such as a first sensor (160A) and a second sensor (160B). Although the PPG signal detection ring (100) is shown in fig. 3 to include two sensors, the number of sensors included in the PPG signal detection ring (100) is not limited to two. In some embodiments, although not shown in fig. 3, the PPG signal detection ring (100) may also include an acceleration sensor.
The first sensor (160A) may include a first wavelength light source (161A), a second wavelength light source (162A), and a photoelectric conversion device (164A). The first sensor (160A) may detect a first wavelength PPG signal using a first wavelength light source (161A) and a photoelectric conversion device (164A). The first sensor (160A) may also detect a second wavelength PPG signal using a second wavelength light source (162A) and a photoelectric conversion device (164A). The first wavelength light source (161A) may for example comprise a red LED, the second wavelength light source (162A) may for example comprise an infrared LED, and the photoelectric conversion device (164A) may comprise a photodiode.
The second sensor (160B) may include a first wavelength light source (161B), a second wavelength light source (162B), and a photoelectric conversion device (164B). The second sensor (160B) may detect the first wavelength PPG signal using a first wavelength light source (161B) and a photoelectric conversion device (164B). The second sensor (160B) may also detect a second wavelength PPG signal using a second wavelength light source (162B) and a photoelectric conversion device (164B). The first wavelength light source (161B) may for example comprise a red LED, the second wavelength light source (162B) may for example comprise an infrared LED, and the photoelectric conversion device (164B) may comprise a photodiode.
The acceleration sensor may detect the motion of the user by measuring the PPG signal to detect the acceleration of the ring (100).
The first terminal (200) may be used by a user. The first terminal (200) may for example comprise a smart phone or a tablet PC. The first terminal (200) may be connected to the PPG signal detection ring (100) by wired or wireless means. For example, the first terminal (200) may be connected to the PPG signal detection ring (100) via bluetooth or Wi-Fi. The first terminal (200) may be connected to the server (300) by a wired or wireless means. For example, the first terminal (200) may be connected to the server (300) by wireless fidelity (WIRELESS FIDELITY, wi-Fi) or mobile telecommunication (mobile telecommunication) technology such as third Generation mobile communication technology (3 rd Generation, 3G), long-Term Evolution (LTE), or fifth Generation mobile communication technology (5 th Generation, 5G).
The first terminal (200) may include a light source control component (210), a sensor selection component (220), a measurement control component (230), and a display component (240). An application may be installed in the first terminal (200). The light source control component (210), the sensor selection component (220), the measurement control component (230), and the display component (240) may be implemented by an application program. Optionally, the first terminal (200) may access a website, and the light source control component (210), the sensor selection component (220), the measurement control component (230), and the display component (240) may be implemented as a website.
The light source control assembly (210) may control the first and second wavelength light sources (161A, 162A) of the first sensor (160A) and the first and second wavelength light sources (161B, 162B) of the second sensor (160B) such that a Direct Current (DC) component of each of the two first wavelength test PPG signals received from the first and second sensors (160A, 160B) is within a first predetermined range and a DC component of each of the two second wavelength test PPG signals received from the first and second sensors (160A, 160B) is within a second predetermined range.
After the light source control assembly (210) controls the first wavelength light source (161A) and the second wavelength light source (162A) of the first sensor (160A) and the first wavelength light source (161B) and the second wavelength light source (162B) of the second sensor (160B), the sensor selection assembly (220) may select one of the first sensor (160A) and the second sensor (160B) as a sensor for measuring the first wavelength light source (161A) and the second wavelength light source (162A) later. The sensor selection component (220) may select among the first sensor (160A) and the second sensor (160B) a sensor that measured a combination of the first wavelength test PPG signal and the second wavelength test PPG signal of the highest signal quality of the two first wavelength test PPG signals and the two second wavelength test PPG signals from the first sensor (160A) and the second sensor (160B). For example, a sensor may be selected that measures a combination of a first wavelength test PPG signal and a second wavelength test PPG signal having the highest average of signal quality among the two first wavelength test PPG signals and the two second wavelength test PPG signals. Signal quality is assessed by at least one of acceleration signal magnitude, signal-to-noise ratio (Signal to Noise Ratio, SNR), and AC component magnitude to DC component magnitude ratio. The smaller the acceleration signal size, the higher the signal-to-noise ratio and the higher the AC component size to DC component size ratio, the higher the signal quality. The first wavelength PPG signal and the second wavelength PPG signal may then be measured at a sensor selected by a sensor selection component (220).
The control of the first wavelength light source (161A) and the second wavelength light source (162A) of the first sensor (160A), the first wavelength light source (161B) and the second wavelength light source (162B) of the second sensor (160B) by the light source control unit (210), and the selection of the sensor by the sensor selection unit (220) may be performed sequentially. That is, after the light source control unit (210) controls the first wavelength light source (161A) and the second wavelength light source (162A) of the first sensor (160A) and the first wavelength light source (161B) and the second wavelength light source (162B) of the second sensor (160B), the sensor selection unit (220) may select the sensors.
The control of the first wavelength light source (161A) and the second wavelength light source (162A) of the first sensor (160A), the first wavelength light source (161B) and the second wavelength light source (162B) of the second sensor (160B) by the light source control unit (210), and the selection of the sensor by the sensor selection unit (220) may be performed periodically. Since the PPG signal detection ring (100) is movable or rotatable relative to the finger, the light source control assembly (210) may control the first wavelength light source (161A) and the second wavelength light source (162A) of the first sensor (160A), the first wavelength light source (161B) and the second wavelength light source (162B) of the second sensor (160B), and the sensor selection assembly (220) may periodically select the sensors.
The measurement control component (230) may select a measurement mode or start or end a measurement based on user input. For example, a user may select a measurement mode from a self-test mode and a background mode using a measurement control component (230). In self-test mode, the user can start and end measurements using the measurement control component (230). In background mode, measurements are started and continued regardless of user input. In background mode, the user may set or alter the measurement period. In some embodiments, the PPG signal detection ring (100) may include a measurement control component (230). That is, the user may use the PPG signal to detect the measurement control component (230) of the ring (100) to select a measurement mode or to begin or end a measurement. In some embodiments, the server (300) may include a measurement control component (230). That is, the service provider may use the measurement control component (230) of the server (300) to select a measurement mode or to begin or end a measurement.
The display component (240) may display at least one of: the method comprises measuring and storing a first wavelength PPG signal and a second wavelength PPG signal by a PPG signal detection ring (100) in a PPG signal storage component (381) of a server (300), measuring a date and time of the first wavelength PPG signal and the second wavelength PPG signal stored in the PPG signal storage component (381) of the server (300), a signal quality classification result classified by a signal quality classification component (320) of the server (300) and stored in an oxygen saturation storage component (382) of the server (300), an oxygen saturation estimated by an oxygen saturation estimation component (350) of the server (300) and stored in an oxygen saturation storage component (382) of the server (300), and an oxygen saturation index calculated by an oxygen saturation index calculation component (360) of the server (300) and stored in an oxygen saturation index storage component (383).
The server (300) may include a PPG signal preprocessing component (310), a signal quality classification component (320), an oxygen saturation estimation component (350), a PPG signal storage component (381), and an oxygen saturation storage component (382). In some embodiments, the server (300) may also include an oxygen saturation index calculation component (360) and an oxygen saturation index storage component (383). In some embodiments, the server (300) may also include an alarm component (370).
The PPG signal preprocessing component (310) may preprocess a first wavelength PPG signal and a second wavelength PPG signal received by the server (300) from a selected sensor of the PPG signal detection ring (100) through the first terminal (200). For example, the first wavelength PPG signal and the second wavelength PPG signal may be preprocessed using a low pass filter, a high pass filter, and Normalization (Normalization). In some embodiments, the PPG signal preprocessing component (310) may preprocess an acceleration signal received by the server (300) from an acceleration sensor of the PPG signal detection ring (100) through the first terminal (200).
A signal quality classification component (320) may classify signal quality of the first wavelength PPG signal and the second wavelength PPG signal as good or bad. In some embodiments, the signal quality classification component (320) may reference the acceleration signal to classify the signal quality of the first wavelength PPG signal and the second wavelength PPG signal as one of good or bad.
Oxygen saturation estimated from the first wavelength PPG signal and the second wavelength PPG signal classified as bad quality may be determined to be unreliable and may not be displayed by the display component (240) of the first terminal (200). The oxygen saturation estimated from the first wavelength PPG signal and the second wavelength PPG signal classified as good quality may be determined to be reliable and may be displayed by a display component (240) of the first terminal (200). In an optional embodiment, the oxygen saturation estimated from the first wavelength PPG signal and the second wavelength PPG signal may be displayed by a display component (240) of the first terminal (200) together with the signal quality classification result, regardless of the signal quality classification result. In addition, the oxygen saturation estimated from the first wavelength PPG signal and the second wavelength PPG signal may be displayed by a display component (420) of the second terminal (400) together with the signal quality classification result, regardless of the signal quality classification result.
In some embodiments, the signal quality classification component (320) may use a deep learning model to classify the quality of the PPG signal as good or bad. The deep learning model used in the signal quality classification component (320) may include a convolutional neural network (convolution neural network, CNN), a Long Short-Term Memory network (LSTM), a fully-connected network (Fully Connected Network, FCN), an encoder, a decoder, or a combination thereof. The method of classification of signal quality is not limited to the methods described herein.
An oxygen saturation estimating component (350) may estimate oxygen saturation from the first wavelength PPG signal and the second wavelength PPG signal. Various methods may be used to estimate oxygen saturation.
For example, the R value may be calculated first by the following equation 1.
R= ((AC R)/(DCR))/((ACIR)/(DCIR)) (formula 1)
Wherein AC R is the magnitude of the AC component of the first wavelength PPG signal, DC R is the magnitude of the DC component of the first wavelength PPG signal, AC IR is the magnitude of the AC component of the second wavelength PPG signal, and DC IR is the magnitude of the DC component of the second wavelength PPG signal.
Next, oxygen saturation may be calculated from the R value using the following equation 2.
Oxygen saturation = C 0-C1 R (2)
C 0 and C 1 are constants that can be determined using linear regression.
In equation 2, oxygen saturation is expressed as a linear equation with respect to the R value, but oxygen saturation may be expressed as a polynomial greater than 1 with respect to the R value, such as a quadratic equation or a cubic equation. The method of estimating oxygen saturation is not limited to the method described herein.
An oxygen saturation index calculation component (360) may calculate an oxygen saturation index. The oxygen saturation index may be defined in terms of a time when the signal quality classification component (320) classifies the quality of the first and second wavelength PPG signals as good and the oxygen saturation estimated by the oxygen saturation estimation component (350) deviates from a normal range. For example, the oxygen saturation index may be defined as the ratio of the time that the signal quality classification component (320) classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good and the oxygen saturation estimated by the oxygen saturation estimation component (350) deviates from the normal range to the time that the signal quality classification component (320) classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good. That is, the oxygen saturation index may refer to a ratio of a time when the oxygen saturation deviates from a normal range to a time when reliable oxygen saturation can be obtained.
The alarm component (370) may send an alarm to at least one of the first terminal (200) and the second terminal (400) when at least one of the oxygen saturation estimated by the oxygen saturation estimating component (350) and the oxygen saturation index calculated by the oxygen saturation index calculating component (360) satisfies the alarm condition set by the alarm condition setting component (410) of the second terminal (400).
The PPG signal preprocessing component (381) may store the first wavelength PPG signal and the second wavelength PPG signal received by the server (300) from the selected sensor of the PPG signal detection ring (100) through the first terminal (200). The PPG signal storage component (381) may also store the date and time of measurement of the first wavelength PPG signal and the second wavelength PPG signal. The PPG signal storage component (381) may also store the first wavelength PPG signal and the second wavelength PPG signal preprocessed by the PPG signal preprocessing component (310). The PPG signal storage component (381) may store acceleration signals received by the server (300) from an acceleration sensor of the PPG signal detection ring (100) through the first terminal (200). The oxygen saturation storage component (382) may store the oxygen saturation estimated by the oxygen saturation estimation component (350). The oxygen saturation level storage component (382) may also store the signal quality classification result classified by the signal quality classification component (320). The oxygen saturation index storage component (383) may store the oxygen saturation index calculated by the oxygen saturation index calculation component (360).
The second terminal (400) may be connected to the server (300) by wire or wirelessly. For example, the second terminal (400) may connect to the server (300) through Wi-Fi or mobile telecommunication (mobile telecommunication) technology such as 3G, LTE or 5G. The second terminal (400) may be used by a physician. The second terminal (400) may for example comprise a smart phone, a tablet PC, a computer or a notebook computer.
The second terminal (400) may include an alarm condition setting component (410) and a display component (420). The second terminal (400) may access a website or be installed with an application. The alarm condition setting component (410) and the display component (420) can be implemented using a website or application.
The doctor may use the alarm condition setting component (410) to set an alarm condition. For example, an alarm may be set to sound when oxygen saturation is less than 90% for 10 minutes or more.
The display component (420) may display at least one of: the first and second wavelength PPG signals from the PPG signal storage component (381), the date and time of measurement of the first and second wavelength PPG signals from the PPG signal storage component (381), the preprocessed first and second wavelength PPG signals stored in the PPG signal storage component (381), the signal quality classification result from the oxygen saturation storage component (382), the oxygen saturation from the oxygen saturation storage component (382), and the oxygen saturation index of the oxygen saturation index storage component (383).
Fig. 4 is a flow chart of an oxygen saturation estimation method (2000) for detecting a ring using a PPG signal.
Referring to fig. 3 and 4, the server (300) may receive a first wavelength PPG signal and a second wavelength PPG signal from a selected sensor of the PPG signal detection ring (100) through the first terminal (200) (S2050). Next, the PPG signal preprocessing component (310) may preprocess the first wavelength PPG signal and the second wavelength PPG signal (S2100). For example, the first wavelength PPG signal and the second wavelength PPG signal may be preprocessed using a low pass filter, a high pass filter, and Normalization (Normalization). In some embodiments, the PPG signal preprocessing component (310) may also preprocess an acceleration signal received by the server (300) from an acceleration sensor of the PPG signal detection ring (100) through the first terminal (200).
Next, the signal quality classification component (320) may classify the signal quality of the first wavelength PPG signal and the second wavelength PPG signal as good or bad (S2200). The signal quality classification component (320) may reference the acceleration signal to classify the signal quality of the first wavelength PPG signal and the second wavelength PPG signal as good or bad. Oxygen saturation estimated from the first wavelength PPG signal and the second wavelength PPG signal classified as bad quality may be determined to be unreliable and may not be displayed by the display component (240) of the first terminal (200). The oxygen saturation estimated from the first wavelength PPG signal and the second wavelength PPG signal classified as good quality may be determined to be reliable and may be displayed by a display component (240) of the first terminal (200). In an optional embodiment, the oxygen saturation estimated from the first wavelength PPG signal and the second wavelength PPG signal may be displayed by a display component (240) of the first terminal (200) together with the signal quality classification result, regardless of the signal quality classification result. In addition, the oxygen saturation estimated from the first wavelength PPG signal and the second wavelength PPG signal may be displayed by a display component (420) of the second terminal (400) together with the signal quality classification result, regardless of the signal quality classification result.
In some embodiments, the signal quality classification component (320) may use a deep learning model. The deep learning model used in the signal quality classification component (320) may include a convolutional neural network (convolution neural network, CNN), a Long Short-Term Memory network (LSTM), a fully-connected network (Fully Connected Network, FCN), an encoder, a decoder, or a combination thereof. The method of classification of signal quality is not limited to the methods described herein.
Next, the oxygen saturation estimating component (350) may estimate oxygen saturation from the first wavelength PPG signal and the second wavelength PPG signal (S2500). The method of estimating oxygen saturation is the same as described above with reference to fig. 3.
Next, the first wavelength PPG signal, the second wavelength PPG signal, the signal quality classification result, and the oxygen saturation may be stored (S2570). The first wavelength PPG signal and the second wavelength PPG signal may be stored in a PPG signal storage component (381). In some embodiments, the preprocessed first and second wavelength PPG signals may also be stored in a PPG signal storage component (381). In some embodiments, the acceleration signal may also be stored in a PPG signal storage component (381). In some embodiments, the preprocessed acceleration signal may also be stored in a PPG signal storage component (381). The signal quality classification result and oxygen saturation may be stored in an oxygen saturation storage component (382).
Next, the following steps may be repeated: the method includes receiving first and second wavelength PPG signals (S2050), preprocessing the first and second wavelength PPG signals (S2100), classifying the first and second wavelength PPG signals (S2220), estimating oxygen saturation (S2500), and storing (S2570).
Next, the oxygen saturation index calculating component (360) may calculate an oxygen saturation index (S2600). The oxygen saturation index may be defined in terms of a time when the signal quality classification component (320) classifies the quality of the first and second wavelength PPG signals as good and the oxygen saturation estimated by the oxygen saturation estimation component (350) deviates from a normal range. For example, the oxygen saturation index may be defined as the ratio of the time that the signal quality classification component (320) classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good and the oxygen saturation estimated by the oxygen saturation estimation component (350) deviates from the normal range to the time that the signal quality classification component (320) classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good. That is, the oxygen saturation index may refer to a ratio of a time when the oxygen saturation deviates from a normal range to a time when reliable oxygen saturation can be obtained.
Next, the oxygen saturation index may be stored in the oxygen saturation index storage component (383) (S2700).
Fig. 5 is a flowchart of a method (3000) of setting up a sensor for PPG signal detection ring.
Referring to fig. 5 and 3, the light source control assembly (210) may control the first and second wavelength light sources (161A, 162A) of the first sensor (160A) and the first and second wavelength light sources (161B, 162B) of the second sensor (160B) such that the DC component of each of the two first wavelength test PPG signals received from the first and second sensors (160A, 160B) is within a first predetermined range and the DC component of each of the two second wavelength test PPG signals received from the first and second sensors (160A, 160B) is within a second predetermined range (S3100).
After the light source control assembly (210) controls the first and second wavelength light sources (161A, 162A) of the first sensor (160A) and the first and second wavelength light sources (161B, 162B) of the second sensor (160B), the sensor selection assembly (220) may select one of the first and second sensors (160A, 160B) as a sensor (S3200) for measuring the first and second wavelength light sources (161A, 162A) later. The sensor selection component (220) may select among the first sensor (160A) and the second sensor (160B) a sensor that measured a combination of the first wavelength test PPG signal and the second wavelength test PPG signal of the highest signal quality of the two first wavelength test PPG signals and the two second wavelength test PPG signals from the first sensor (160A) and the second sensor (160B). For example, a sensor may be selected that measures a combination of a first wavelength test PPG signal and a second wavelength test PPG signal having the highest average of signal quality among the two first wavelength test PPG signals and the two second wavelength test PPG signals. Signal quality is assessed by at least one of acceleration signal magnitude, signal-to-noise ratio (Signal to Noise Ratio, SNR), and AC component magnitude to DC component magnitude ratio. The smaller the acceleration signal size, the higher the signal-to-noise ratio and the higher the AC component size to DC component size ratio, the higher the signal quality. Thereafter, the first wavelength PPG signal and the second wavelength PPG signal measured by the sensor selected by the sensor selection component (220) may be transmitted to the server (300) through the first terminal (200).
The control (S3100) of the first wavelength light source (161A) and the second wavelength light source (162A) of the first sensor (160A), the first wavelength light source (161B) and the second wavelength light source (162B) of the second sensor (160B) by the light source control unit (210), and the selection (S3200) of the sensor by the sensor selection unit (220) may be sequentially performed. That is, after the light source control unit (210) controls the first wavelength light source (161A) and the second wavelength light source (162A) of the first sensor (160A) and the first wavelength light source (161B) and the second wavelength light source (162B) of the second sensor (160B), the sensor selection unit (220) may select the sensors.
The control (S3100) of the first wavelength light source (161A) and the second wavelength light source (162A) of the first sensor (160A), the first wavelength light source (161B) and the second wavelength light source (162B) of the second sensor (160B) by the light source control unit (210), and the selection of the sensor by the sensor selection unit (220) may be periodically performed (S3200). Since the PPG signal detection ring (100) is movable or rotatable relative to the finger, the light source control assembly (210) may control the first wavelength light source (161A) and the second wavelength light source (162A) of the first sensor (160A), the first wavelength light source (161B) and the second wavelength light source (162B) of the second sensor (160B), and the sensor selection assembly (220) may periodically select the sensors.
The embodiments disclosed in the present disclosure are not intended to limit the technical ideas of the present disclosure, but are for illustrative purposes, and the scope of the technical ideas of the present disclosure is not limited to these embodiments. The scope of the present disclosure should be construed in accordance with the appended claims, and all technical ideas within the equivalent scope thereof should be construed to be included in the scope of the claims of the present disclosure.
Claims (10)
1. An oxygen saturation estimation system for detecting a ring using a photoplethysmography (Photoplethysmography, PPG) signal, the system comprising a server comprising:
a signal quality classification component configured to classify the quality of the first wavelength PPG signal and the second wavelength PPG signal as good or bad; and
An oxygen saturation estimating component configured to estimate oxygen saturation from the first wavelength PPG signal and the second wavelength PPG signal,
Wherein the first wavelength PPG signal and the second wavelength PPG signal are measured using the PPG signal detection ring, the server receives the first wavelength PPG signal and the second wavelength PPG signal from the PPG signal detection ring through a terminal,
The PPG signal detection ring comprises a plurality of sensors located at different positions,
Each of the plurality of sensors is configured to measure a first wavelength PPG signal and a second wavelength PPG signal,
Each of the plurality of sensors includes a first wavelength light source, a second wavelength light source, and a photoelectric conversion device,
The terminal comprises a sensor selection component configured to select, among the plurality of sensors, a sensor that measures a combination of a first wavelength test PPG signal and a second wavelength test PPG signal of highest signal quality among a plurality of first wavelength test PPG signals and a plurality of second wavelength test PPG signals as a sensor for measuring the first wavelength PPG signal and the second wavelength PPG signal.
2. The oxygen saturation estimation system for detecting a ring using a PPG signal according to claim 1,
The signal quality of the plurality of test PPG signals is evaluated by at least one of an acceleration signal magnitude, a signal-to-noise ratio, and a ratio of alternating current (ALTERNATING CURRENTD, AC) component magnitude to Direct Current (DC) component magnitude.
3. The oxygen saturation estimation system for detecting a ring using a PPG signal according to claim 1,
The server further includes an oxygen saturation index calculation component configured to calculate an oxygen saturation index,
The oxygen saturation index is defined as a ratio of a time when the signal quality classification component classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good and the oxygen saturation deviates from a normal range to a time when the signal quality classification component classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good.
4. The oxygen saturation estimation system for detecting a ring using a PPG signal according to claim 1,
The terminal further includes a light source control component configured to control the first wavelength light source and the second wavelength light source of each of the plurality of sensors such that a DC component of each of a plurality of first wavelength test PPG signals measured using the plurality of sensors, respectively, is within a first predetermined range and a DC component of each of a plurality of second wavelength test PPG signals measured using the plurality of sensors, respectively, is within a second predetermined range.
5. The oxygen saturation estimation system for detecting a ring using a PPG signal of claim 4,
The control of the first wavelength light source and the second wavelength light source by the light source control component and the selection of the sensor by the sensor selection component are sequentially carried out,
And the control of the light source control assembly to the first wavelength light source and the second wavelength light source and the selection of the sensor by the sensor selection assembly are periodically carried out.
6. An oxygen saturation estimation method for detecting a ring using a PPG signal, comprising: receiving, by a terminal, a first wavelength PPG signal and a second wavelength PPG signal from a PPG signal detection ring;
classifying the quality of the first wavelength PPG signal and the second wavelength PPG signal as good or bad; and
Estimating oxygen saturation from the first wavelength PPG signal and the second wavelength PPG signal,
Wherein the PPG signal detection ring comprises a plurality of sensors positioned at different positions,
Each of the plurality of sensors is configured to measure a first wavelength PPG signal and a second wavelength PPG signal,
Each of the plurality of sensors includes a first wavelength light source, a second wavelength light source, and a photoelectric conversion device,
The terminal comprises a sensor selection component configured to select, among the plurality of sensors, a sensor that measures a combination of a first wavelength test PPG signal and a second wavelength test PPG signal of highest signal quality among a plurality of first wavelength test PPG signals and a plurality of second wavelength test PPG signals as a sensor for measuring the first wavelength PPG signal and the second wavelength PPG signal.
7. The method of oxygen saturation estimation for a ring using PPG signals according to claim 6, wherein,
The signal quality of the plurality of test PPG signals is evaluated by at least one of an acceleration signal magnitude, a signal-to-noise ratio, and an AC component magnitude to DC component magnitude ratio.
8. The method of oxygen saturation estimation for a ring using PPG signals according to claim 6, further comprising:
the oxygen saturation index is calculated and the oxygen saturation,
Wherein the oxygen saturation index is defined as a ratio of a time when the signal quality classification component classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good and the oxygen saturation deviates from a normal range to a time when the signal quality classification component classifies the quality of the first wavelength PPG signal and the second wavelength PPG signal as good.
9. The method of oxygen saturation estimation for a ring using PPG signals according to claim 6, wherein,
The terminal further includes a light source control component configured to control the first wavelength light source and the second wavelength light source of each of the plurality of sensors such that a DC component of each of a plurality of first wavelength test PPG signals respectively measured using the plurality of sensors is within a first predetermined range and a DC component of each of a plurality of second wavelength test PPG signals respectively measured using the plurality of sensors is within a second predetermined range.
10. The method of oxygen saturation estimation for a ring using PPG signals according to claim 9, wherein,
The control of the first wavelength light source and the second wavelength light source by the light source control component and the selection of the sensor by the sensor selection component are sequentially carried out,
And the control of the light source control assembly to the first wavelength light source and the second wavelength light source and the selection of the sensor by the sensor selection assembly are periodically carried out.
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| KR10-2021-0124275 | 2021-09-16 | ||
| KR1020210124275A KR20230040761A (en) | 2021-09-16 | 2021-09-16 | Oxygen saturation estimation system using PPG signal sensing ring |
| PCT/KR2022/013738 WO2023043199A1 (en) | 2021-09-16 | 2022-09-14 | Oxygen saturation estimation system using ppg signal sensing ring |
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| JP4710084B2 (en) * | 2005-07-15 | 2011-06-29 | コニカミノルタセンシング株式会社 | Biological information measuring device |
| JP4607709B2 (en) * | 2005-08-26 | 2011-01-05 | シャープ株式会社 | Detection device |
| KR20150082038A (en) * | 2014-01-07 | 2015-07-15 | 삼성전자주식회사 | Electronic device and photoplethysmography method |
| KR102434698B1 (en) * | 2015-07-03 | 2022-08-22 | 삼성전자주식회사 | Apparatus and method for detecting biological information |
| KR20200091625A (en) * | 2019-01-23 | 2020-07-31 | 삼성전자주식회사 | Bio signal measurement apparatus and method |
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