CN117976065A - Intelligent gene detection database management system - Google Patents

Intelligent gene detection database management system Download PDF

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Publication number
CN117976065A
CN117976065A CN202410249228.8A CN202410249228A CN117976065A CN 117976065 A CN117976065 A CN 117976065A CN 202410249228 A CN202410249228 A CN 202410249228A CN 117976065 A CN117976065 A CN 117976065A
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application
gene
information
gene detection
detection data
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CN202410249228.8A
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Inventor
张倩
陈新
秦利涛
王怡辉
董�成
廖世秀
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Henan Provincial Peoples Hospital
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Henan Provincial Peoples Hospital
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Priority to CN202410249228.8A priority Critical patent/CN117976065A/en
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Abstract

The invention provides an intelligent gene detection database management system, which comprises a database module, a management module, an application module and a transmission module; the database module is used for storing gene detection data, wherein the gene detection data comprises gene sequence data and gene characteristic information; the management module is used for classifying and managing the gene detection data of the database module according to the gene characteristic information; the application module is used for receiving the gene detection data application information sent by the institution terminal to carry out approval verification and obtain an approval verification result; the gene detection data application information comprises characteristic information and application form information of required gene data; the transmission module is used for extracting corresponding gene detection data from the database module according to the approval verification result, carrying out privacy processing, and transmitting the gene detection data after the privacy processing to the designated institution terminal. The invention is helpful to improve the intelligent level and the safety of the gene detection data storage management and the data resource utilization management.

Description

Intelligent gene detection database management system
Technical Field
The invention relates to the technical field of gene detection database management, in particular to an intelligent gene detection database management system.
Background
The establishment of the gene database plays a very important role in medicine and scientific research.
At present, for the management of gene detection data, after gene detection is performed by a patient under the active or passive condition, the gene detection data of the patient is stored in a centralized manner, and a centralized management database is established. However, the established gene database is generally only stored due to the influence of security privacy regulations and the like, so that important resources cannot be applied to subsequent treatment and medical research for patients. Therefore, there is a need to establish a management system that can intelligently manage a gene detection database and can assist in further calling gene detection data on the basis of adapting to security privacy protection.
Disclosure of Invention
Aiming at the technical problems that the management system which can carry out intelligent management on the gene detection database and can help to call the gene detection data further on the basis of adapting to the security privacy protection is required at present, the invention aims to provide an intelligent gene detection database management system.
The aim of the invention is realized by adopting the following technical scheme:
the invention discloses an intelligent gene detection database management system, which comprises a database module, a management module, an application module and a transmission module; wherein,
The database module is used for storing gene detection data, wherein the gene detection data comprises gene sequence data and gene characteristic information; the gene characteristic information comprises a gene detection result corresponding to the gene sequence data and basic patient information;
the management module is used for classifying and managing the gene detection data of the database module according to the gene characteristic information,
The application module is used for receiving the application information of the gene detection data sent by the institution terminal, and carrying out approval verification according to the application information to obtain an approval verification result; the gene detection data application information comprises characteristic information and application form information of required gene data;
The transmission module is used for extracting corresponding gene detection data from the database module according to the approval verification result, carrying out privacy processing on the extracted gene detection data, and transmitting the gene detection data after the privacy processing to the appointed institution terminal.
Preferably, the system further comprises an acquisition module, wherein the acquisition module comprises an acquisition unit and an input unit;
The acquisition unit is used for acquiring a gene detection sequence transmitted by the gene detection equipment, wherein the gene sequence data comprises a DNA sequence or an RNA sequence;
The input unit is used for inputting corresponding gene characteristic information according to the acquired gene sequence data and marking the gene data sequence according to the input gene characteristic information.
Preferably, the patient basic information includes patient name, sex, age, race, height, weight, family history, disease type, etc.;
The gene detection results include wild type and mutant type.
Preferably, the management module includes:
grouping and managing the gene detection data in the database module according to one or more pieces of gene characteristic information corresponding to the gene detection data, and classifying the gene detection data into different groups; wherein the genetic test data can belong to one or more groups.
Preferably, the application module comprises a receiving unit, an application verification unit, an institution verification unit and an output unit; wherein,
The receiving unit is used for receiving the gene detection data application information sent by the institution terminal, wherein the gene detection data application information comprises characteristic information and application form information of required gene data;
the application verification unit is used for carrying out approval verification on the acquired application form information to obtain an application form approval verification result;
The mechanism verification unit is used for verifying qualification of the mechanism sending the application to obtain a mechanism approval verification result;
The output unit is used for outputting corresponding approval verification results according to the application form approval verification results and the mechanism approval verification results.
Preferably, the application form information includes application requirements, wherein the application requirements include scientific and clinical applications;
The application form information of the scientific application comprises characteristic information corresponding to scientific project information and gene detection data required by scientific research;
The application form information of the clinical application contains the identity information of the appointed patient, the family personnel information related to the patient and the authorization information of the family personnel.
Preferably, the application verification unit comprises a scientific application verification unit and a clinical application verification unit;
The scientific research application verification unit is used for verifying the examination and approval files of the scientific research project according to the application form information of the scientific research application, acquiring the backup of the examination and approval files for archiving management, and obtaining an application form examination and approval verification result after the examination and approval files pass the verification.
The clinical application verification unit is used for verifying family personnel information related to a patient aiming at application form information of a clinical application, and further verifying authorization information of the family personnel after verification is passed to obtain an application form approval verification result.
Preferably, the clinical application verification unit includes:
Acquiring an authorized recorded video of a family person, extracting a portrait picture in the acquired authorized recorded video, and verifying the identity information of the family person on the extracted portrait picture based on a face recognition technology to obtain an identity verification result;
Further extracting audio data of the authorized recording video, performing text transfer processing according to the obtained audio data to obtain corresponding voice text data, and performing authorization information verification according to the obtained voice text data to obtain an authorization verification result;
and when the identity verification result and the authorization verification result pass, obtaining an application form approval verification result as passing.
Preferably, the mechanism verification unit specifically includes:
when acquiring the application information of the gene detection data submitted by the organization terminal, carrying out identity verification on the organization terminal user, acquiring corresponding organization qualification information according to the acquired organization identity information, and carrying out qualification verification according to the acquired organization qualification information to obtain an organization approval verification result.
Preferably, the transmission module comprises a feedback unit, an extraction unit, a privacy processing unit and an encryption transmission unit;
the feedback unit is used for returning the failed approval verification result to the mechanism terminal when the approval verification result is failed;
the extraction unit is used for extracting gene detection data corresponding to the gene characteristic information from the database module according to the application information corresponding to the passing approval verification result;
The privacy processing unit is used for carrying out privacy processing according to the extracted gene detection data, eliminating private identity information in the gene privacy data and obtaining the gene detection data to be transmitted after the privacy processing;
the encryption transmission unit further encrypts the gene detection data to be transmitted and transmits the encrypted gene detection data to the corresponding institution terminal.
The beneficial effects of the invention are as follows: the invention provides an intelligent gene detection database management system, which is used for centrally storing gene detection data by constructing a database module and classifying and managing the gene detection data in the database module based on a management module. After the application module obtains the application information of the gene detection data sent by the institution terminal (such as a medical institution, a scientific research institution and the like), the application information can be intelligently verified, when the application information passes the verification, the corresponding gene detection data is extracted from the database according to the application information of the institution terminal, and after the privacy processing of the gene detection data is finished, the gene detection data is transmitted to the corresponding institution terminal. Through the management system, centralized classifying, storing and managing of the gene monitoring data can be realized, the data application of the institution is subjected to intelligent approval, the required gene detection data is subjected to privacy treatment and then transmitted to the corresponding institution terminal, and on one hand, the intelligent level of the gene detection data storage management and the data resource utilization management can be improved; on the other hand, the method can adapt to the requirement of the gene detection data on safety privacy, and effectively protect the privacy of the gene detection data under the condition of recycling data resources.
Drawings
The invention will be further described with reference to the accompanying drawings, in which embodiments do not constitute any limitation of the invention, and other drawings can be obtained by one of ordinary skill in the art without inventive effort from the following drawings.
FIG. 1 is a block diagram of an intelligent genetic testing database management system according to an embodiment of the present invention;
FIG. 2 is a block diagram of a framework of an application module according to an embodiment of the present invention;
fig. 3 is a frame structure diagram of a transmission module according to an embodiment of the present invention.
Detailed Description
The invention is further described in connection with the following application scenario.
Referring to an intelligent gene detection database management system shown in the embodiment of fig. 1, the system comprises a database module, a management module, an application module and a transmission module; wherein,
The database module is used for storing gene detection data, wherein the gene detection data comprises gene sequence data and gene characteristic information; the gene characteristic information comprises a gene detection result corresponding to the gene sequence data and basic patient information;
the management module is used for classifying and managing the gene detection data of the database module according to the gene characteristic information,
The application module is used for receiving the application information of the gene detection data sent by the institution terminal, and carrying out approval verification according to the application information to obtain an approval verification result; the gene detection data application information comprises characteristic information and application form information of required gene data;
The transmission module is used for extracting corresponding gene detection data from the database module according to the approval verification result, carrying out privacy processing on the extracted gene detection data, and transmitting the gene detection data after the privacy processing to the appointed institution terminal.
According to the embodiment of the invention, an intelligent gene detection database management system is provided, a database module is built to intensively store gene detection data, and the gene detection data in the database module are classified and managed based on the management module. After the application module obtains the application information of the gene detection data sent by the institution terminal (such as a medical institution, a scientific research institution and the like), the application information can be intelligently verified, when the application information passes the verification, the corresponding gene detection data is extracted from the database according to the application information of the institution terminal, and after the privacy processing of the gene detection data is finished, the gene detection data is transmitted to the corresponding institution terminal. Through the management system, centralized classifying, storing and managing of the gene monitoring data can be realized, the data application of the institution is subjected to intelligent approval, the required gene detection data is subjected to privacy treatment and then transmitted to the corresponding institution terminal, and on one hand, the intelligent level of the gene detection data storage management and the data resource utilization management can be improved; on the other hand, the method can adapt to the requirement of the gene detection data on safety privacy, and effectively protect the privacy of the gene detection data under the condition of recycling data resources.
Preferably, the system further comprises an acquisition module, wherein the acquisition module comprises an acquisition unit and an input unit;
The acquisition unit is used for acquiring a gene detection sequence transmitted by the gene detection equipment, wherein the gene sequence data comprises a DNA sequence or an RNA sequence;
The input unit is used for inputting corresponding gene characteristic information according to the acquired gene sequence data and marking the gene data sequence according to the input gene characteristic information.
In the above embodiment, the management system may further access to the gene detection device, and after the gene detection device completes the gene detection, the obtained gene sequence data may be marked and stored in the database module, so as to further adapt to the requirement of the gene detection data acquisition.
Preferably, the patient basic information includes patient name, sex, age, race, height, weight, family history, disease type, etc.;
The gene detection results include wild type and mutant type.
According to the obtained gene sequence data, the basic information corresponding to the patient is related to the gene sequence data so as to perfect the integrity of the gene detection data; meanwhile, according to the gene sequence data, marking of the gene detection result is carried out according to the gene sequence characteristics, so that basis is provided for realizing classification management of the gene sequence data characteristics.
The gene characteristic information can also contain other characteristic information such as corresponding gene names, so as to perfect characteristic calibration aiming at gene sequence data and improve the classifying management effect.
Preferably, the management module includes:
grouping and managing the gene detection data in the database module according to one or more pieces of gene characteristic information corresponding to the gene detection data, and classifying the gene detection data into different groups; wherein the genetic test data can belong to one or more groups.
In the above embodiment, when the gene test data is classified and managed, the gene test data may be classified based on basic information of the corresponding patient (for example, the gene test data may be classified by using [ race, sex, age ] or the like as a combined characteristic reference factor, or the gene test data may be classified by using a single characteristic such as [ height ] as a reference factor), or the gene test data may be classified based on the result of the gene test (for example, wild type or mutant type).
Preferably, referring to the embodiment of fig. 2, the application module includes a receiving unit, an application verification unit, an institution verification unit, and an output unit; wherein,
The receiving unit is used for receiving the gene detection data application information sent by the institution terminal, wherein the gene detection data application information comprises characteristic information and application form information of required gene data;
the application verification unit is used for carrying out approval verification on the acquired application form information to obtain an application form approval verification result;
The mechanism verification unit is used for verifying qualification of the mechanism sending the application to obtain a mechanism approval verification result;
The output unit is used for outputting corresponding approval verification results according to the application form approval verification results and the mechanism approval verification results.
In the above embodiment, the application module performs respective intelligent approval verification on the qualification of the organization and the application information according to the application information sent by the organization terminal; aiming at the application form information, carrying out approval verification on key information (such as application requirement type, scientific research project approval information, authorization information and the like) in the application form information so as to ensure that the application information meets the related safety privacy and procedural requirements; aiming at the institutions, intelligent verification is carried out on real-time qualification information (such as qualification approval for developing genetic scientific research, registration information of medical institutions and the like) of the institutions, and the compliance of the application institutions is ensured. And after the application form approval verification and the mechanism approval verification are respectively finished, obtaining a corresponding approval verification result.
Preferably, the application form information includes application requirements, wherein the application requirements include scientific and clinical applications;
the application form information of the scientific research application comprises characteristic information corresponding to scientific research project information and gene detection data required by scientific research;
The application form information of the clinical application contains the identity information of the appointed patient, the family personnel information related to the patient and the authorization information of the family personnel.
The application requirements for the genetic detection data are generally divided into two cases, in one case, for example, when a research institution for genetic research performs project research, it is required to request to obtain genetic detection data of a certain characteristic range (for example, a specific crowd, such as a specific crowd conforming to a specific [ race, sex, age ]) to perform related scientific research activities, where related genetic detection data (for example, a plurality of groups of genetic detection data satisfying a specific characteristic crowd as samples) is applied by means of scientific research application. In another case, for example, when a medical institution needs to perform further medical analysis on a specific patient, it is required to request to acquire gene detection data of other patients having a family blood relationship with the patient as a study sample, so as to analyze the condition of the specific patient laterally, in which case, the acquisition of gene detection data of the related family personnel is requested by means of a clinical application.
Preferably, the application verification unit comprises a scientific application verification unit and a clinical application verification unit;
the scientific research application verification unit is used for verifying the examination and approval gene detection data of the scientific research project according to application form information of the scientific research application, acquiring the examination and approval gene detection data backup for archiving management, and obtaining an application form examination and approval verification result after the examination and approval gene detection data passes the verification.
The clinical application verification unit is used for verifying family personnel information related to a patient aiming at application form information of a clinical application, and further verifying authorization information of the family personnel after verification is passed to obtain an application form approval verification result.
In the above embodiment, the application form information of the different application requirement types is verified based on the application forms of the two different application requirement types, and the corresponding verification unit is specifically provided, where the application form information of the scientific application is used to backup and approve related approval gene detection data (such as the approval results of the project study book and the related departments of the tumor patient) through the scientific application verification unit, so as to ensure legal compliance and safety of the application. The application form information of the clinical application is considered, when the institution carries out the gene detection information of the appointed personnel or the related family personnel of the patient, the gene detection information is equivalent to the identity information of the related personnel of the gene detection information which is known in advance by the institution, so that the related personnel is verified in association with the clinical application form information, and the authorization information of the specific related personnel is verified, thereby ensuring that the gene detection data of the related personnel are truly authorized for use.
Preferably, the clinical application verification unit includes:
Acquiring an authorized recorded video of a family person, extracting a portrait picture in the acquired authorized recorded video, and verifying the identity information of the family person on the extracted portrait picture based on a face recognition technology to obtain an identity verification result;
Further extracting audio data of the authorized recording video, performing text transfer processing according to the obtained audio data to obtain corresponding voice text data, and performing authorization information verification according to the obtained voice text data to obtain an authorization verification result;
and when the identity verification result and the authorization verification result pass, obtaining an application form approval verification result as passing.
The related family personnel authorize the medical institution in a mode of recording an authorization video, so that the medical institution sequentially applies for the gene detection data of the personnel for further study; the management system can carry out identity verification and authorization verification on the authorization video of family personnel based on the image recognition technology through the clinical application verification unit, and the intelligent level of application approval verification is effectively improved.
Preferably, the mechanism verification unit specifically includes:
when acquiring the application information of the gene detection data submitted by the organization terminal, carrying out identity verification on the organization terminal user, acquiring corresponding organization qualification information according to the acquired organization identity information, and carrying out qualification verification according to the acquired organization qualification information to obtain an organization approval verification result.
Preferably, referring to the embodiment of fig. 3, the transmission module includes a feedback unit, an extraction unit, a privacy processing unit, and an encryption transmission unit;
the feedback unit is used for returning the failed approval verification result to the mechanism terminal when the approval verification result is failed;
the extraction unit is used for extracting gene detection data corresponding to the gene characteristic information from the database module according to the application information corresponding to the passing approval verification result;
The privacy processing unit is used for carrying out privacy processing according to the extracted gene detection data, eliminating private identity information in the gene privacy data and obtaining the gene detection data to be transmitted after the privacy processing;
the encryption transmission unit further encrypts the gene detection data to be transmitted and transmits the encrypted gene detection data to the corresponding institution terminal.
In the above embodiment, after the application approval verification for the gene detection data is completed, the extracting unit extracts the corresponding gene detection data from the database module according to the application information, and the privacy processing unit erases, hides or falsifies the privacy information (such as the patient identity information corresponding to the gene detection data) in the gene detection data, so as to eliminate the key privacy information in the gene detection data, only preserve the genetic characteristic information in the gene detection data, avoid the leakage of the privacy information, and improve the safety of the gene detection data management. When the gene detection data is transmitted to the corresponding institution terminal, encryption processing is carried out particularly on the gene detection data, so that the safety problem caused by leakage in the data transmission process is avoided, and the safety of gene detection data management is further improved.
Preferably, the encryption transmission unit performs encryption processing on the gene detection data to be transmitted, including:
Acquiring a data extraction instruction Zx initiated by the mechanism terminal according to the approval verification result, and recording a first time feature ty 1 corresponding to the data extraction instruction (for example, the time ty 1 = 202310011644 when the mechanism terminal sends the data extraction instruction) according to the acquired data extraction instruction Zx; the data extraction instruction comprises corresponding gene detection data application information a;
Obtaining corresponding gene detection data x to be transmitted according to a data extraction instruction, and extracting a second time feature ty 0 (for example, the time ty 0 = 202309281157 when a mechanism terminal sends out the gene detection data application information) and a corresponding mechanism identity feature nf (for example, nf=015 is obtained according to a mechanism ID) carried in the gene detection data application information according to application information a of the gene detection data;
Extracting a pre-stored mechanism public key g nf according to the acquired mechanism identity characteristic nf; obtaining a time difference characteristic ts=t 1-ty0 according to the first time characteristic ty 1 and the second time characteristic ty 0; obtaining the current key iteration quantity according to the time difference characteristics and the pre-stored iteration time interval tg Wherein/>Representing an upward rounding function, i.e., the operation result is an upward rounding result;
Encrypting the gene detection data x to be transmitted according to the mechanism public key g nf and the key iteration amount ig, wherein the gene detection data x to be transmitted is repeatedly encrypted for ig times by adopting the mechanism public key g nf to obtain encrypted gene detection data Wherein/>Representing cryptographic processing functions, i.e. using public keys/>Encryption processing of data x,/>The superscript k 1,k2,…,kig in (1) denotes the number of times of the current encryption processing, wherein/>Carrying out ig repeated encryption treatment on the gene detection data x by adopting a mechanism public key g nf to obtain encrypted gene detection data x'; and transmits the encrypted gene detection data x' to the corresponding institution terminal.
So that in a corresponding embodiment, after receiving the gene detection data x', the mechanism terminal calculates a time difference feature ts=ty 1-ty0 according to the time feature ty 0 corresponding to the application information a of the self-sent gene detection data and the time feature ty 1 corresponding to the initiation data extraction instruction; obtaining the current key iteration quantity according to the time difference characteristics and the pre-stored iteration time interval tgDecrypting the gene detection data x 'according to the mechanism private key s nf and the key iteration amount ig corresponding to the mechanism terminal, wherein the gene detection data x' is repeatedly decrypted for ig times by adopting the mechanism private key s nf to obtain the required gene detection data/>Wherein/>Representing the decryption processing function, i.e. using private key/>Decryption of data x'/>, andThe superscript k 1,k2,…,kig in (1) denotes the number of times of the current decryption process, wherein/>And (3) the mechanism terminal performs ig repeated decryption processing on the gene detection data x' by adopting the mechanism privacy g nf to obtain decrypted gene detection data y.
The mechanism terminal transmits the public key of the mechanism to the management system in advance for archiving and backup, and the public key is adopted when the subsequent data is encrypted.
In one scenario, regarding the extraction of temporal features, it is possible to precision to different units of temporal data, for example, to date, temporal feature ty 0 = 20230928, and to minute, temporal feature ty 0 = 202309281157; wherein the first temporal feature and the second temporal feature employ the same accuracy;
The iteration time interval tg may be set to, for example, 00000001 or 000000000030 or the like according to the actual situation.
In the above embodiment, after the institution terminal initiates a gene detection data application to the system, according to the approval verification result of the management system for the gene detection data application, when the approval verification result passes, the institution terminal logs in the management system again to request to acquire the required gene detection data; the management system encrypts the gene detection data to be transmitted through the encryption transmission unit, wherein the encryption processing is particularly carried out on the gene detection data in a repeated encryption mode according to time interval characteristics, and the repeated encryption times can be obtained by converting the time difference between the initiation of gene data application and the acquisition of data as the time characteristics through the repeated encryption mode, so that the gene detection data is repeatedly encrypted by adopting a mechanism public key; considering the privacy of the application of the gene detection data, the related time information only includes the organization itself (more specifically, the manager performing the data acquisition operation) and the management system, so that even if the encrypted gene detection data is intercepted and the organization privacy is compromised, the security of the gene detection data can still be effectively ensured (avoiding the condition that the gene detection data (including the current and historical) acquired by the organization terminal is compromised due to the disclosure of the private key or the disclosure of the organization characteristic information in the traditional encryption mode), and even if the private key information is obtained under the condition that the encrypted data is intercepted, the encrypted data cannot be effectively decrypted as soon as the repeated encryption times are known under the condition that the time characteristic cannot be known, thereby effectively improving the security of the gene detection data in the process of being transmitted back to the organization terminal and effectively ensuring the privacy protection of the gene detection data. Meanwhile, the encryption scheme does not need additional data interaction in the encryption process, and is suitable for the use of the current data management system.
It should be noted that, in each embodiment of the present invention, each functional unit/module may be integrated in one processing unit/module, or each unit/module may exist alone physically, or two or more units/modules may be integrated in one unit/module. The integrated units/modules described above may be implemented either in hardware or in software functional units/modules.
From the description of the embodiments above, it will be apparent to those skilled in the art that the embodiments described herein may be implemented in hardware, software, firmware, middleware, code, or any suitable combination thereof. For a hardware implementation, the processor may be implemented in one or more of the following units: an Application Specific Integrated Circuit (ASIC), a Digital Signal Processor (DSP), a Digital Signal Processing Device (DSPD), a Programmable Logic Device (PLD), a Field Programmable Gate Array (FPGA), a processor, a controller, a microcontroller, a microprocessor, other electronic units designed to perform the functions described herein, or a combination thereof. For a software implementation, some or all of the flow of an embodiment may be accomplished by a computer program to instruct the associated hardware. When implemented, the above-described programs may be stored in or transmitted as one or more instructions or code on a computer-readable medium. Computer-readable media includes both computer storage media and communication media including any medium that facilitates transfer of a computer program from one place to another. A storage media may be any available media that can be accessed by a computer. Computer-readable media can include, but are not limited to, RAM, ROM, EEPROM, CD-ROM or other optical disk storage, magnetic disk storage media or other magnetic storage devices, or any other medium that can be used to carry or store desired program code in the form of instructions or data structures and that can be accessed by a computer.
Finally, it should be noted that the above embodiments are only for illustrating the technical solution of the present invention, and not for limiting the scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solution of the present invention without departing from the spirit and scope of the technical solution of the present invention.

Claims (9)

1. An intelligent gene detection database management system is characterized by comprising a database module, a management module, an application module and a transmission module; wherein,
The database module is used for storing gene detection data, wherein the gene detection data comprises gene sequence data and gene characteristic information; the gene characteristic information comprises a gene detection result corresponding to the gene sequence data and basic patient information;
the management module is used for classifying and managing the gene detection data of the database module according to the gene characteristic information,
The application module is used for receiving the application information of the gene detection data sent by the institution terminal, and carrying out approval verification according to the application information to obtain an approval verification result; the gene detection data application information comprises characteristic information and application form information of required gene data;
The transmission module is used for extracting corresponding gene detection data from the database module according to the approval verification result, carrying out privacy processing on the extracted gene detection data, and transmitting the gene detection data after the privacy processing to the appointed institution terminal.
2. The intelligent genetic testing database management system of claim 1, further comprising an acquisition module, wherein the acquisition module comprises an acquisition unit and an entry unit;
The acquisition unit is used for acquiring a gene detection sequence transmitted by the gene detection equipment, wherein the gene sequence data comprises a DNA sequence or an RNA sequence;
The input unit is used for inputting corresponding gene characteristic information according to the acquired gene sequence data and marking the gene data sequence according to the input gene characteristic information.
3. The intelligent genetic testing database management system of claim 1, wherein the patient base information comprises patient name, gender, age, race, height, weight, family history, disease type;
The gene detection results include wild type and mutant type.
4. The intelligent genetic testing database management system of claim 1, wherein the management module comprises:
grouping and managing the gene detection data in the database module according to one or more pieces of gene characteristic information corresponding to the gene detection data, and classifying the gene detection data into different groups; wherein the genetic test data can belong to one or more groups.
5. The intelligent genetic testing database management system of claim 1, wherein the application module comprises a receiving unit, an application verification unit, an institution verification unit, and an output unit; wherein,
The receiving unit is used for receiving the gene detection data application information sent by the institution terminal, wherein the gene detection data application information comprises characteristic information and application form information of required gene data;
the application verification unit is used for carrying out approval verification on the acquired application form information to obtain an application form approval verification result;
The mechanism verification unit is used for verifying qualification of the mechanism sending the application to obtain a mechanism approval verification result;
The output unit is used for outputting corresponding approval verification results according to the application form approval verification results and the mechanism approval verification results.
6. The intelligent genetic testing database management system of claim 5, wherein the application form information comprises application requirements, wherein the application requirements comprise scientific and clinical applications; the application form information of the scientific application comprises characteristic information corresponding to scientific project information and gene detection data required by scientific research; the application form information of the clinical application comprises the identity information of a specified patient, family personnel information related to the patient and authorization information of the family personnel;
The application verification unit comprises a scientific research application verification unit and a clinical application verification unit;
The scientific research application verification unit is used for verifying the examination and approval files of the scientific research project according to the application form information of the scientific research application, acquiring the backup of the examination and approval files for archiving management, and obtaining an application form examination and approval verification result after the examination and approval files pass the verification.
The clinical application verification unit is used for verifying family personnel information related to a patient aiming at application form information of a clinical application, and further verifying authorization information of the family personnel after verification is passed to obtain an application form approval verification result.
7. The intelligent gene testing database management system of claim 6, wherein the clinical application verification unit comprises:
Acquiring an authorized recorded video of a family person, extracting a portrait picture in the acquired authorized recorded video, and verifying the identity information of the family person on the extracted portrait picture based on a face recognition technology to obtain an identity verification result;
Further extracting audio data of the authorized recording video, performing text transfer processing according to the obtained audio data to obtain corresponding voice text data, and performing authorization information verification according to the obtained voice text data to obtain an authorization verification result;
and when the identity verification result and the authorization verification result pass, obtaining an application form approval verification result as passing.
8. The intelligent genetic testing database management system of claim 5, wherein the institution authentication unit comprises:
when acquiring the application information of the gene detection data submitted by the organization terminal, carrying out identity verification on the organization terminal user, acquiring corresponding organization qualification information according to the acquired organization identity information, and carrying out qualification verification according to the acquired organization qualification information to obtain an organization approval verification result.
9. The intelligent genetic testing database management system of claim 1, wherein the transmission module comprises a feedback unit, an extraction unit, a privacy processing unit, and an encryption transmission unit;
the feedback unit is used for returning the failed approval verification result to the mechanism terminal when the approval verification result is failed;
the extraction unit is used for extracting gene detection data corresponding to the gene characteristic information from the database module according to the application information corresponding to the passing approval verification result;
The privacy processing unit is used for carrying out privacy processing according to the extracted gene detection data, eliminating private identity information in the gene privacy data and obtaining the gene detection data to be transmitted after the privacy processing;
the encryption transmission unit further encrypts the gene detection data to be transmitted and transmits the encrypted gene detection data to the corresponding institution terminal.
CN202410249228.8A 2024-03-05 2024-03-05 Intelligent gene detection database management system Pending CN117976065A (en)

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