CN117883170A - Flexible multi-mode ablation needle with pipeline side-by-side structure - Google Patents

Abstract

The application provides a flexible multimode ablation needle with a pipeline side-by-side structure, which comprises the following components: a flexible tube, the distal end of which is connected to the needle; the air inlet pipeline and the first air return pipeline penetrate through the flexible pipeline and are arranged in parallel, the air inlet pipeline and the first air return pipeline are provided with contact surfaces extending along the axial direction, and the air inlet pipeline and the first air return pipeline are respectively positioned at two sides of the contact surfaces; the vacuum forming layer is arranged among the air inlet pipeline, the first air return pipeline and the flexible pipeline; a pipeline switching structure; the air inlet pipeline penetrates through the vacuum switching chamber and the return air switching chamber and extends out from the proximal end of the return air switching chamber. According to the flexible multi-mode ablation needle, when a refrigerating working medium enters the inner cavity of the air inlet pipe for heat exchange, the contact surface enables the air return cavity to synchronously perform heat exchange, so that rapid heat exchange is realized, and the working end part of the needle head meets the temperature required by treatment.

Description

Flexible multi-mode ablation needle with pipeline side-by-side structure

Technical Field

The embodiment of the application relates to the technical field of medical instruments, in particular to a flexible multi-mode ablation needle with a pipeline side-by-side structure.

Background

The main difference between the flexible multi-mode ablation needle and the traditional multi-mode ablation needle (percutaneous puncture) is that: the flexible multi-mode ablation needle has a longer pipeline (about 1 m) entering the human body part, and usually the air inlet cavity and the air return cavity of the flexible needle are in coaxial structures, the two cavities are not contacted with each other, and when the freezing working medium flows through the air inlet cavity and the air return cavity, the original normal-temperature gas in the cavity needs to be converted into low-temperature gas, and the phenomenon is called heat exchange. The coaxial structure has requirements on the air pressure and the conversion time of the freezing working medium during air intake, otherwise, the working end of the needle head cannot reach the temperature of freezing treatment, and the freezing effect is affected.

Therefore, a contact type parallel structure of an air inlet pipeline and an air return pipeline is needed, and the air return pipeline exchanges heat synchronously while the air inlet pipeline exchanges heat, so that the working end can quickly reach the temperature required by treatment.

Disclosure of Invention

In view of the above, the present application provides a flexible multi-modal ablation needle in a side-by-side configuration of tubing to overcome or at least partially address the above-described problems.

The embodiment of the application provides a flexible multi-mode ablation needle with a pipeline side-by-side structure, which comprises the following components: a flexible tube, the distal end of which is connected to the needle; the air inlet pipeline and the first air return pipeline penetrate through the flexible pipeline and are arranged in parallel, the air inlet pipeline and the first air return pipeline are provided with contact surfaces extending along the axial direction, and the air inlet pipeline and the first air return pipeline are respectively positioned at two sides of the contact surfaces; the vacuum forming layer is arranged among the air inlet pipeline, the first air return pipeline and the flexible pipeline; pipeline switching structure includes: a vacuum transfer chamber, the proximal end of which is communicated with the vacuum forming layer, and the distal end of which is communicated with the vacuum passage; the near end of the return air switching chamber is communicated with the first return air pipeline, and the far end of the return air switching chamber is communicated with the second return air pipeline; the air inlet pipeline penetrates through the vacuum switching chamber and the return air switching chamber and extends out from the proximal end of the return air switching chamber.

Optionally, a gap is arranged between the distal end of the first air return pipeline and the distal end of the air inlet pipeline, and the length of the gap is 3-8 mm.

Optionally, the distal end of the air intake conduit is proximal to the needle.

Optionally, the cross-sectional shapes of the air inlet pipeline and the first air return pipeline are selected from semicircle, square and rectangle.

Optionally, the air intake conduit completely overlaps or partially overlaps an opposing surface of the first air return conduit.

Optionally, the multi-modal ablation needle further comprises a vacuum housing; the remote end of the air return shell is suitable for being connected with the air inlet pipeline and the first air return pipeline respectively, and the air return shell and the vacuum shell form a vacuum switching chamber; the air seat and the air return shell form an air return switching chamber, and the air seat is suitable for being connected with the far end of the vacuum shell; the air inlet pipeline penetrates through the flexible pipeline, penetrates through the vacuum switching chamber, the return air switching chamber and the air seat respectively, and extends out of the proximal end of the air seat.

Optionally, the air seat is provided with a connecting portion extending along an axial direction, and the axial width of the connecting portion is such that at least part of the connecting portion is in contact with the proximal end of the vacuum housing when the air inlet pipeline and the guide pipeline are assembled.

Optionally, the vacuum transfer chamber and the return air transfer chamber are integrally formed.

Optionally, the vacuum passage is connected to a vacuum forming apparatus, and the vacuum forming layer, the vacuum transfer chamber and the vacuum passage form a vacuum when the vacuum forming apparatus is operated.

According to the technical scheme, the flexible multi-mode ablation needle is characterized in that the air inlet pipeline and the first air return pipeline are arranged in parallel and are provided with the contact surface extending along the axial direction, when a refrigerating working medium enters the inner cavity of the air inlet pipe for heat exchange, the contact surface enables the air return cavity to synchronously exchange heat, and rapid heat exchange is realized so that the working end part of the needle head meets the temperature required by treatment.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the embodiments of the present application, and other drawings may be obtained according to these drawings for a person having ordinary skill in the art.

FIG. 1 is a cross-sectional view of an integrated structure of a flexible multi-modal ablation needle vacuum housing of the application;

FIG. 2 is a cross-sectional view of a distal portion of an integral structure of the flexible multi-modal ablation needle vacuum enclosure shown in FIG. 1;

FIG. 3 is a cross-sectional view of a split construction of a flexible multimode ablation needle vacuum housing of the application;

FIG. 4 is a cross-sectional view of a split structure of a vacuum housing of a flexible multimode ablation needle of the application with a first housing and a second housing unassembled;

FIGS. 5A-5C are side views of an embodiment of the air intake and return lines of the flexible multi-modality ablation needle of the present application from the distal end;

FIGS. 6A-6C are side views from the distal end of another embodiment of an air intake and return line of a flexible multi-modality ablation needle of the present application;

FIGS. 7A-7C are side views from the distal end of an embodiment of the air intake and return lines of the flexible multi-modality ablation needle of the present application;

fig. 8-10 are schematic views of different embodiments of the split-structure first housing and second housing connecting portions of a flexible multi-mode ablation needle vacuum housing of the application, respectively.

Element labels

101: A vacuum housing; 102: a first housing; 103: a flexible conduit; 104: a second housing; 105: an air return housing; 106: an air intake line; 107: a first return air line; 108: a vacuum transfer chamber; 109: an air seat; 110: an air return switching chamber; 112: a first sidewall; 113: a first boss; 114: a second boss; 115: a second sidewall; 116: a guide pipeline; 117: a connection part; 118: a first transfer line; 119: a second transfer line; 121: a temperature measuring device; 122: a radio frequency circuit; 123: a contact surface; 124: vacuum forming a layer.

Detailed Description

In order to better understand the technical solutions in the embodiments of the present application, the following description will clearly and completely describe the technical solutions in the embodiments of the present application with reference to the accompanying drawings in the embodiments of the present application, and it is obvious that the described embodiments are only some embodiments of the present application, not all embodiments. All other embodiments, which are derived by a person skilled in the art based on the embodiments of the present application, shall fall within the scope of protection of the embodiments of the present application.

The 'distal end' refers to the left side end of the flexible multi-mode ablation needle shown in the figure; the "proximal end" refers to the right side end of the flexible multi-modality ablation needle as shown in the figures.

The implementation of the embodiments of the present application will be further described below with reference to the accompanying drawings.

Referring to fig. 1-8, in one specific implementation of the present application, a flexible multi-modal ablation needle is provided in a side-by-side-tube configuration, the flexible multi-modal ablation needle comprising: a flexible tube, the distal end of which is connected to the needle; the air inlet pipeline and the first air return pipeline penetrate through the flexible pipeline and are arranged in parallel, the air inlet pipeline and the first air return pipeline are provided with contact surfaces extending along the axial direction, and the air inlet pipeline and the first air return pipeline are respectively positioned at two sides of the contact surfaces; the vacuum forming layer is arranged among the air inlet pipeline, the first air return pipeline and the flexible pipeline; pipeline switching structure includes: a vacuum transfer chamber, the proximal end of which is communicated with the vacuum forming layer, and the distal end of which is communicated with the vacuum passage; the near end of the return air switching chamber is communicated with the first return air pipeline, and the far end of the return air switching chamber is communicated with the second return air pipeline; the air inlet pipeline penetrates through the vacuum switching chamber and the return air switching chamber and extends out from the proximal end of the return air switching chamber. When the frozen working medium enters the inner cavity of the air inlet pipe for heat exchange, the contact surface enables the return air cavity to synchronously exchange heat, so that the quick heat exchange is realized, and the working end part of the needle head meets the temperature required by treatment.

In an embodiment, a gap is arranged between the far end of the first air return pipeline and the far end of the air inlet pipeline, the distance between the far end of the first air return pipeline and the far end of the air inlet pipeline can be 3-10 mm, the far end of the air inlet pipeline is farther away from the far end of the first air return pipeline, and when the air inlet pipeline works, the frozen working medium reaches the needle head, so that the working medium is discharged from the first air return pipeline after the needle head is fully frozen.

In one embodiment, the distance between the far end of the air inlet pipeline and the needle head is 3-8 mm, and the needle head can be quickly frozen to form an ice ball during operation.

In one embodiment, as shown in fig. 3-5C, the cross-sectional shape of the intake conduit and the first return conduit is selected from a semi-circular shape, a square shape, a rectangular shape, or any other suitable shape. The intake conduit is either fully overlapped or partially overlapped with an opposing surface of the first return conduit.

In one embodiment, the multi-modal ablation needle further includes a vacuum housing comprising: a first housing having a distal end connected to the flexible tubing; a second housing, a proximal end of the second housing adapted to connect with a distal end of the first housing; the remote end of the air return shell is suitable for being connected with the air inlet pipeline and the first air return pipeline respectively, and the air return shell and the vacuum shell form a vacuum switching chamber; the air seat and the air return shell form an air return switching chamber, and the air seat is suitable for being connected with the far end of the second shell; the air inlet pipeline penetrates through the flexible pipeline, penetrates through the vacuum switching chamber, the air return switching chamber and the air seat respectively, extends out of the proximal end of the air seat, and can be adjusted to be connected with the first shell and the air seat based on the length of the air inlet pipeline. In another embodiment, the vacuum transfer chamber and the return air transfer chamber may be of an integrally formed construction. The vacuum transfer chamber and the return air transfer chamber enable the air inlet pipeline and the return air pipeline to form independent cavity structures, and the independent cavity structures are not interfered with each other during working.

In an embodiment, a first side wall and a first boss connected to the first side wall are disposed at a proximal end of the first housing, a second boss and a second side wall connected to the second boss are disposed at a distal end of the second housing, and the second boss is movable relative to the first boss to adjust a contact area between the second boss and the first boss. When the second boss moves to the most far end, the second boss is abutted against the first side wall, and the second side wall is abutted against the first boss.

In an embodiment, the air seat is provided with a guide pipeline sleeved outside the air inlet pipeline, and the guide pipeline can axially move relative to the air inlet pipeline when assembled and is connected with the air inlet pipeline when assembled. The guide pipeline provides an internal channel for the air inlet pipeline, and the guide pipeline and the air inlet pipeline are fixedly connected, so that the rigidity of the air inlet pipeline is increased, and the air inlet pipeline is prevented from being broken.

In one embodiment, the air seat is provided with a connecting portion extending along the axial direction, and the axial width of the connecting portion is such that at least part of the connecting portion is in contact with the proximal end of the second housing when the air inlet pipeline and the guide pipeline are assembled.

The air holder 109 is in communication with the return air transfer chamber 110 and the vacuum transfer chamber 108, respectively. The air inlet pipeline 106 and the first air return pipeline 107 are both arranged in the flexible pipeline 103 in a penetrating way, and the proximal end of the first air return pipeline 107 is communicated with the air return switching chamber 110.

In one embodiment, the air seat 109 is provided with: a first transfer line 118 in communication with the return air transfer chamber 110; a second transfer line 119 in communication with the vacuum transfer chamber 108.

In one embodiment, the first air return pipe 107 is coaxially sleeved outside the air inlet pipe 106, and a vacuum forming layer is disposed between the first air return pipe 107, the needle and the flexible pipe 103. In another embodiment, the first air return line 107 and the air inlet line 106 may be and are disposed in independent relationship, and a vacuum forming layer is disposed between the first air return line 107 and the air inlet line 106, the needle, and the flexible line 103.

In one embodiment, the distal end of the flexible tubing 103 is connected to a needle, and the air inlet tubing 106 is connected to the needle; a temperature measuring device 121 is disposed in the first air return line 107, and a proximal end of the temperature measuring device 121 is connected to the host. The temperature measuring device 121 may be a thermocouple. The air holder 109 is connected to an RF circuit 122, and the proximal end of the RF circuit 122 is connected to a host computer to transmit the energy generated by the host computer to the air holder 109 and to the needle via the air inlet pipe 106.

The flexible pipeline 103 can be flexible pipe with good lubricity and insulation, the flexible pipeline 103 can be made of high polymer materials such as PTFE, nylon, PEBAX, the outer diameter of the flexible pipeline 103 can be 1 mm-4 mm, and the length of the flexible pipeline 103 can be 100 mm-3000 mm. The fifth pipeline 123105 may be made of metal, such as stainless steel 304, 316L, brass, copper, etc. The third and fourth pipes 104 and 122 may be PTFE, nylon, PEBAX or the like.

In one embodiment, the vacuum transfer chamber 108 may be connected to a vacuum passageway and through the vacuum passageway to a vacuum forming apparatus (e.g., a vacuum pump) that, when in operation, forms a vacuum with the vacuum forming layer, the vacuum transfer chamber 108, and the vacuum passageway. When the vacuum degree reaches the required requirement, the multi-mode ablation device starts to transmit work, and the vacuum forming device always keeps working during the whole working period of the multi-mode ablation device, so that the maintenance of the vacuum degree of the vacuum layer structure is ensured.

The return air switching chamber 110 may also be connected to the refrigerant recovery device through a second return air line, and the air intake line 106 is connected to the refrigerant output device. When the refrigerating medium output device and the refrigerating medium recovery device work, the refrigerating medium output by the refrigerating medium output device enters the air inlet pipeline 106 and is recovered to the refrigerating medium recovery device through the second air return pipeline.

The pipeline and the parts have dimensional tolerance, and the tolerance accumulation phenomenon can occur when the pipeline and the parts are assembled together, so that the assembled parts need to be fixed and sealed, and therefore, certain requirements are placed on the assembly size; the split structure of the vacuum housing 101 can effectively compensate the assembly difficulty caused by accumulated tolerance, and can be a size compensation structure. When the assembly size is slightly error, the assembly position of the second housing 104 can be adjusted through displacement when the first housing 102 and the second housing 104 are assembled, so that the welding points between the two vacuum housings 101 and the welding points between the second housing 104 and the air seat 109 are ensured to play a role in fixing and sealing.

In one embodiment, the distal end of the first housing 102 is assembled with the flexible tubing 103, the guide tube 116 is assembled with the air holder 109, and the air inlet tube 106 is assembled with the guide tube 116, and the proximal end of the guide tube 116 is aligned with the proximal end of the air inlet tube 106, so that the relative positions of the air holder 109 and the second housing 104 need to be adjusted. When the air seat 109 needs to be adjusted proximally, a gap is formed between the first side wall 112 of the first housing 102 and the side wall of the second boss 114 of the second housing 104, and the first boss 113 and the second boss 114 can be designed to match with the position adjustment of the air seat 109, so that even if a gap is formed between the first side wall 112 of the first housing 102 and the side wall of the second boss 114 of the second housing 104, the first boss 113 and the second boss 114 can be tightly connected in a sealing manner. The sealing connection may be by welding.

Meanwhile, since the first housing 102 and the second housing 104 are independent from each other before being assembled, and are assembled when in use, compared with the structure of the first housing 102 and the second housing 104 integrally formed, the distal end of the return air switching chamber 110 of the embodiment of the application can be welded to the outside of the air inlet pipe and the air return pipe more accurately and efficiently, and the structure of the first housing 102 and the second housing 104 integrally formed can be welded to an accurate position only by multiple attempts due to the large axial depth of the first housing 102 and the second housing 104.

Compared with the traditional multimode ablation needle (percutaneous puncture type), the flexible multimode ablation needle provided by the embodiment of the application is mainly different in that: the flexible multi-mode ablation needle has a longer pipeline (about 1 m) entering the human body part, and the outer tube material is usually a flexible polymer material, so that the deflation coefficient under the vacuum condition is very high, and therefore, if a mode of manufacturing a vacuum tube in advance by adopting a conventional probe is adopted, the high vacuum degree of the flexible probe needle tube is difficult to maintain for a long time.

During operation, the endoscope firstly passes through the natural cavity (oral cavity, anus, urethra and the like) of the human body, then enters and finds the lesion position by matching with the light source and the imaging system of the endoscope, and then the flexible freezing catheter enters through the instrument channel of the endoscope until the lesion tissue is subjected to operation treatment, so that the technical problem that the metal hard rod of the probe cannot be bent to enter along with the natural cavity and can only enter through the needle puncture is solved. Avoiding the conditions of damage, bleeding and the like of the skin caused by puncture.

The working modes of the existing probe are single freezing or radio frequency modes, and the like, so that the freezing requirements of precise control and rapid precooling of multi-mode ablation are difficult to be achieved. Because of different patients and different lesion organs, the lesion positions are different, if the patients meet the severe lesion positions, the difficulty of the operation is improved, the operation time is prolonged, and the success rate of the operation is reduced. The endoscope can enter a severe lesion position from a natural cavity of a human body through the bending angle of the front end, and the multi-mode ablation device enters the lesion position through the internal channel of the endoscope and finally reaches the lesion position through bending of the multi-mode ablation device. While probes can only make destructive punctures to tissue, once the walls of the lumen are pierced, the resulting result is often fatal.

When the multi-mode ablation device works in operation, the freezing medium can reach the needle head through the air inlet pipeline 106 to perform cryoablation on tumor tissues, and the vacuum layer plays a role in heat insulation when the ablation needle works. However, most of the vacuum layers of the current probes are prefabricated, not real-time suction, and if the vacuum layers leak or the vacuum degree is reduced before use, the vacuum layers can damage patients and instruments. The connection mode of the vacuum passage and the vacuum forming device can be VCR joint sealing connection, and also can be connected and sealed through the metal eduction tube and the emulsion tube, the connection mode is not limited, and the sealing effect can be achieved.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the embodiments of the present application, and are not limited thereto; although the application has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present application.

Claims (10)

1. A flexible multi-modal ablation needle in a side-by-side configuration of tubing, the flexible multi-modal ablation needle comprising:

A flexible tube, the distal end of which is connected to the needle;

the air inlet pipeline and the first air return pipeline penetrate through the flexible pipeline and are arranged in parallel, the air inlet pipeline and the first air return pipeline are provided with contact surfaces extending along the axial direction, and the air inlet pipeline and the first air return pipeline are respectively positioned at two sides of the contact surfaces;

the vacuum forming layer is arranged among the air inlet pipeline, the first air return pipeline and the flexible pipeline;

pipeline switching structure includes:

a vacuum transfer chamber, the proximal end of which is communicated with the vacuum forming layer, and the distal end of which is communicated with the vacuum passage;

the near end of the return air switching chamber is communicated with the first return air pipeline, and the far end of the return air switching chamber is communicated with the second return air pipeline;

the air inlet pipeline penetrates through the vacuum switching chamber and the return air switching chamber and extends out from the proximal end of the return air switching chamber.

2. The flexible multimode ablation needle of claim 1, wherein a gap is provided between the distal end of the first return air line and the distal end of the inlet air line, the gap having a length of 3-8 mm.

3. The flexible multimode ablation needle of claim 1, wherein the distal end of the air inlet tube is proximal to the needle head.

4. The flexible multimode ablation needle of claim 1, wherein the cross-sectional shape of the air inlet conduit and the first air return conduit is selected from the group consisting of semi-circular, square, and rectangular.

5. The flexible multimode ablation needle of claim 1, wherein the air inlet conduit completely overlaps or partially overlaps an opposing surface of the first air return conduit.

6. The flexible multimode ablation needle of claim 1, wherein the multimode ablation needle further comprises:

A vacuum housing;

the remote end of the air return shell is suitable for being connected with the air inlet pipeline and the first air return pipeline respectively, and the air return shell and the vacuum shell form a vacuum switching chamber;

The air seat and the air return shell form an air return switching chamber, and the air seat is suitable for being connected with the far end of the vacuum shell;

The air inlet pipeline penetrates through the flexible pipeline, penetrates through the vacuum switching chamber, the return air switching chamber and the air seat respectively, and extends out of the proximal end of the air seat.

7. The flexible multimode ablation needle of claim 6, wherein the air seat is provided with a guide pipeline sleeved outside the air inlet pipeline, and the guide pipeline can axially move relative to the air inlet pipeline when assembled and is connected with the air inlet pipeline when assembled.

8. The flexible multimode ablation needle of claim 7, wherein the air seat is provided with an axially extending connecting portion having an axial width such that at least a portion of the connecting portion contacts the proximal end of the vacuum housing when the air inlet conduit is assembled with the guide conduit.

9. The flexible multimode ablation needle of claim 1, wherein the vacuum transfer chamber and the return air transfer chamber are of unitary construction.

10. The flexible multimode ablation needle of claim 1, wherein the vacuum passageway is connected to a vacuum forming device, and the vacuum forming layer, the vacuum switching chamber and the vacuum passageway form a vacuum when the vacuum forming device is in operation.