CN117796976A - Conveyor and blood flow guiding bracket system - Google Patents
Conveyor and blood flow guiding bracket system Download PDFInfo
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- CN117796976A CN117796976A CN202311804068.0A CN202311804068A CN117796976A CN 117796976 A CN117796976 A CN 117796976A CN 202311804068 A CN202311804068 A CN 202311804068A CN 117796976 A CN117796976 A CN 117796976A
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- flow guiding
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
- A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2002/068—Modifying the blood flow model, e.g. by diffuser or deflector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9528—Instruments specially adapted for placement or removal of stents or stent-grafts for retrieval of stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
- A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
- A61F2002/9665—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod with additional retaining means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Prostheses (AREA)
Abstract
The present application relates to a conveyor and a blood flow guiding stent system. The conveyor is used for conveying a blood flow guiding bracket, and comprises: a delivery guidewire, an elastic washer and an anti-drop ring. The elastic washer is arranged on the conveying guide wire in a sliding way, and the proximal end of the blood flow guiding support is sleeved on the elastic washer. The anti-drop ring is sleeved on the conveying guide wire, the proximal end of the anti-drop ring is abutted with the distal end of the elastic washer, and the proximal end of the anti-drop ring can be embedded into a gap between the elastic washer and the conveying guide wire, so that the radial size of the distal end of the elastic washer is increased. According to the conveyor, when the blood flow guiding support is retracted, the proximal end of the anti-drop ring is embedded into the gap between the conveying guide wire and the elastic washer, so that the radial size of the distal end of the elastic washer is increased, the elastic washer and the blood flow guiding support cannot move relatively, and the proximal end of the blood flow guiding support can be prevented from being separated from the elastic washer.
Description
Technical Field
The invention relates to the technical field of medical appliances, in particular to a conveyor and a blood flow guiding bracket system.
Background
This section provides merely background information related to the present disclosure and is not necessarily prior art.
Intracranial aneurysms are mostly abnormal bulging occurring on the wall of intracranial arteries, and are the first causative agent of subarachnoid hemorrhage. Subarachnoid hemorrhage is one of the main types of clinical hemorrhagic stroke. The aneurysm treatment means mainly comprise two types of surgical clamping and interventional treatment, and clinical experiments show that the mortality rate of the interventional treatment of patients with the aneurysm is lower than that of the surgical treatment.
The blood flow guiding dense net support is a new treatment mode which appears in recent years, the principle is that the correct path of blood vessels at the position of the aneurysm is reconstructed, the blood flow direction is restored, the blood flow direction of intracranial blood vessels can be remodelled, the aneurysm is gradually reduced until the aneurysm disappears, and compared with spring coil embolism treatment, the method has obvious advantages and less long-term problems, and has obvious treatment advantages for large-sized and huge aneurysms.
The blood flow guiding dense net support in the market is usually composed of a support, a conveying guide wire and an introducing sheath, the blood flow guiding support is held in the introducing sheath in a pre-pressing mode through the conveying guide wire, the therapeutic principle is that under the monitoring of medical imaging equipment, the support is conveyed into a microcatheter through the conveying guide wire, then conveyed to a target lesion position through the microcatheter, the support is released in a self-expanding mode, the blood flow dynamics of an aneurysm is changed through the structure with high metal coverage rate and high network porosity of the support, the blood flow flowing into the aneurysm is reduced, the blood flow guiding effect is achieved, thrombus formation in the aneurysm is induced, vascular endothelialization of the neck of the aneurysm is promoted, occlusion of the aneurysm is further achieved, and the purpose of curing the aneurysm is achieved.
Most blood flow guiding brackets in the market are pressed and held in a catheter by extruding the inner wall of the bracket through a cylindrical silica gel pad on a conveying guide wire, the principle that the friction force between the bracket and the silica gel pad is larger than that between the silica gel pad and the inner wall of the catheter is utilized to realize the conveying and recycling of the bracket in the catheter, and when the bracket is conveyed in a blood vessel which is relatively tortuous clinically, the bracket is required to be retracted, the bracket and the silica gel pad can possibly be unloaded due to large recycling resistance of the bracket at the bent blood vessel, so that the bracket cannot be conveyed and recycled normally.
Disclosure of Invention
The object of the present invention is to solve at least one of the above-mentioned problems. The aim is achieved by the following technical scheme:
embodiments of the present application provide a conveyor for conveying a blood flow guiding stent, comprising:
the guide wire is conveyed and guided,
the elastic gasket is arranged on the conveying guide wire in a sliding manner, and the proximal end of the blood flow guiding bracket is sleeved on the elastic gasket; and
The anti-drop ring is sleeved on the conveying guide wire, the proximal end of the anti-drop ring is abutted to the distal end of the elastic gasket, and the proximal end of the anti-drop ring can be embedded into a gap between the elastic gasket and the conveying guide wire, so that the radial size of the distal end of the elastic gasket is increased.
According to the conveyor of the embodiment of the application, when the blood flow guiding support needs to be withdrawn in the microcatheter, as a certain friction force exists between the elastic gasket and the blood flow guiding support, relative sliding does not occur immediately, but the elastic gasket can slide on the conveying guide wire, so that relative movement can occur between the elastic gasket and the blood flow guiding support when the conveying guide wire is withdrawn, the anti-drop ring is fixed on the conveying guide wire, the anti-drop ring can move together with the conveying guide wire, at the moment, the proximal end of the anti-drop ring can be embedded into a gap between the conveying guide wire and the elastic gasket, the radial size of the distal end of the elastic gasket can be increased by the anti-drop ring, so that the mutual pressure between the elastic gasket and the blood flow guiding support is increased, the relative movement between the elastic gasket and the blood flow guiding support is avoided, and the proximal end of the blood flow guiding support can be prevented from being separated from the elastic gasket.
In addition, the conveyor according to the embodiment of the invention can also have the following additional technical features:
in one embodiment, the anti-drop ring comprises a main body part and a proximal part connected with the proximal end of the main body part, wherein the proximal part is in a conical structure, the radial dimension of the proximal part gradually decreases from the distal end to the proximal end, and the proximal part can be embedded into a gap between the elastic gasket and the conveying guide wire.
In one embodiment, the proximal portion has a taper angle of 30 ° -60 °.
In one embodiment, the anti-slip ring further comprises a distal portion connected to the distal end of the main body portion, the distal portion having a tapered configuration, and the radial dimension of the distal portion gradually decreasing from the proximal end to the distal end.
In one embodiment, the slip-off prevention ring is made of a developing material.
In one embodiment, the anti-slip ring surface is provided with a hydrophilic coating.
In one embodiment, the conveyor further comprises a proximal developing ring, the proximal developing ring is sleeved on the conveying guide wire and fixedly connected with the conveying guide wire, and the proximal end of the elastic gasket is abutted to the proximal developing ring.
In one embodiment, the inner diameter of the elastic washer is greater than the inner diameter of the anti-slip ring.
In one embodiment, the delivery device further comprises a spring coil fixedly disposed at the distal end of the delivery guidewire.
The application also provides a blood flow guiding stent system, which comprises a conveyor and a blood flow guiding stent, wherein the blood flow guiding stent is sleeved on the conveying guide wire, and the proximal end of the blood flow guiding stent is positioned on the elastic gasket.
Drawings
Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the invention. Also, like reference numerals are used to designate like parts throughout the figures. In the drawings:
FIG. 1 is a schematic diagram of a blood flow guiding stent delivery system according to an embodiment of the present invention;
FIG. 2 is a schematic view of the blood flow guiding stent of FIG. 1;
FIG. 3 is a schematic view of the conveyor shown in FIG. 1;
FIG. 4 is a schematic view of the spring coil and delivery guidewire of FIG. 3;
FIG. 5 is a schematic view of the anti-slip ring, elastomeric gasket and proximal developer ring of FIG. 3 in a transport configuration;
FIG. 6 is a schematic view of the anti-slip ring, elastomeric washer and proximal developer ring of FIG. 3 in a retracted configuration;
FIG. 7 is a schematic view of the anti-slip ring shown in FIG. 3;
FIG. 8 is a schematic view of the push rod shown in FIG. 3;
FIG. 9 is a schematic illustration of the delivery of the blood flow guiding stent system of FIG. 1 within a microcatheter;
fig. 10 is a schematic view of the blood flow guiding stent system of fig. 9 after release of the blood flow guiding stent.
Detailed Description
Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
It is to be understood that the terminology used herein is for the purpose of describing particular example embodiments only, and is not intended to be limiting. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. The terms "comprises," "comprising," "includes," "including," and "having" are inclusive and therefore specify the presence of stated features, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, steps, operations, elements, components, and/or groups thereof.
Although the terms first, second, third, etc. may be used herein to describe various elements, components, regions, layers and/or sections, these elements, components, regions, layers and/or sections should not be limited by these terms. These terms may be only used to distinguish one element, component, region, layer or section from another region, layer or section. Terms such as "first," "second," and other numerical terms when used herein do not imply a sequence or order unless clearly indicated by the context. Thus, a first element, component, region, layer or section discussed below could be termed a second element, component, region, layer or section without departing from the teachings of the example embodiments.
For ease of description, spatially relative terms, such as "inner," "outer," "lower," "below," "upper," "above," and the like, may be used herein to describe one element or feature's relationship to another element or feature as illustrated in the figures. Such spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" or "beneath" other elements or features would then be oriented "above" or "over" the other elements or features. Thus, the example term "below … …" may include both upper and lower orientations. The device may be otherwise oriented (rotated 90 degrees or in other directions) and the spatial relative relationship descriptors used herein interpreted accordingly.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
In this application, the end that is closer to the operator in use is referred to as the "proximal end", the end that is farther from the operator is referred to as the "distal end", and the "proximal end" and the "distal end" of any component of the conveyor are defined according to this principle.
Referring to fig. 1, a blood flow guiding stent system 10 according to a first embodiment of the present application includes a blood flow guiding stent 100, a delivery device 200 and an introducer sheath 300, wherein the introducer sheath 300 includes a lumen extending along an axial direction, the delivery device 200 is disposed through the lumen, the blood flow guiding stent 100 is sleeved on the delivery device 200 and is disposed in the lumen, and the delivery device 200 is used for delivering the blood flow guiding stent 300 to a lesion (such as an aneurysm).
With continued reference to fig. 1, the diameter of the lumen of the introducer sheath 300 remains constant from the distal end to the proximal end. The proximal end of the introducer sheath 300 has a cylindrical structure, and the distal end has a tapered structure with a taper length of 2mm-5mm, so that the distal end can be conveniently inserted into the microcatheter when in use. In one embodiment, the introducer sheath 300 may be a transparent or translucent color to facilitate viewing of the condition of the blood flow guiding stent 100 within the introducer sheath 300. The introducer sheath 300 may have a single-layer structure, and the material of the single-layer structure may be Pebax (polyether block polyamide), PA (polyamide), HDPE (high density polyethylene) or the like, and the introducer sheath 300 may have a double-layer structure, and the inner layer may be PTFE (polytetrafluoroethylene) material, which has the advantage of making the inner wall smoother, reducing the resistance of the blood flow guiding stent 100 pushing in the inner cavity, and the outer layer of the introducer sheath 300 may be Pebax, PA, HDPE or the like.
Referring also to fig. 2, the blood flow guiding stent 100 is woven from a plurality of woven wires to form a lumen structure. During delivery, the blood flow guiding stent 100 is sleeved on the distal end of the conveyor 200 and compressed into a straightened state, and after release, the blood flow guiding stent 100 can be restored to a state of matching with a blood vessel and attaching to the inner wall of the blood vessel.
In one embodiment, the blood flow guiding stent 100 is woven by 48 or 64 strands of the braided wires 110, the braided wires 110 may be made of nickel-titanium alloy, cobalt-chromium alloy, platinum or alloy thereof, and the wire diameter of the braided wires 110 is 0.0010-0.0016 inches. In an embodiment, the braided wires 110 may be a composite structure, that is, each braided wire 110 is made of an inner layer and an outer layer of materials, the inner core is made of pure platinum, or other platinum alloy materials, or tantalum, gold and other metal materials with high density and good biocompatibility, the braided wires have good developability under DSA (digital subtraction angiography) equipment, the outer layer is made of cobalt-chromium alloy or nickel-titanium alloy, the inner layer platinum accounts for 10% -50% of the wire, the optimal ratio is 20% -35%, the inner layer is made of pure platinum, the advantage of being dependent on the high density performance of the inner layer can be effectively developed under DSA, and an operator can clearly observe the overall profile of the stent and the effect of attaching to a blood vessel after the stent is released.
With continued reference to fig. 2, the two ends of the blood flow guiding support 100 are flared, and an included angle formed by a border of the flared end and a central axis of the blood flow guiding support 100 is 10 ° -45 °, or an included angle formed by a border of the flared end and a central axis of the blood flow guiding support 100 is 15 ° -30 °. The axial length of the flare portion is 0.1mm-2.5mm, or alternatively, the axial length of the flare is 0.15mm-0.3mm. The diameter of the distal end of the flare is 0.2mm-2mm larger than the diameter of the middle portion of the blood flow guiding stent 100 or the diameter of the distal end of the flare is 0.3mm-0.6mm larger than the diameter of the middle portion of the blood flow guiding stent 100. By designing the two ends of the blood flow guiding stent 100 to have a bell mouth structure, when the blood flow guiding stent 100 is released from the microcatheter, the two ends of the blood flow guiding stent 100 can be well unfolded, preventing the occurrence of the fish mouth effect. In addition, when the blood flow guiding stent 100 is released in the blood vessel, the two ends can anchor the blood flow guiding stent 100 more firmly in the blood vessel due to the tension effect of the flare, so that the displacement of the blood flow guiding stent 100 is avoided.
The blood flow guiding stent in the prior art generally adopts braiding firstly and then cutting according to the required length, generally uses a pair of scissors or similar tools to cut a section of longer braided net tube into the required length, but the cutting easily causes the end face of the braided wire of the blood flow guiding stent to form a sharp or pointed section, and the braided wire of the blood flow guiding stent can possibly puncture a microcatheter when the blood flow guiding stent is in the conveying process because the wire diameter of the braided wire is smaller and can not be observed by naked eyes, so that the braided wire of the blood flow guiding stent is reversely folded, the resistance of the conveying blood flow guiding stent is increased, and the blood flow guiding stent is deformed, so that the blood flow guiding stent can not be normally released. With continued reference to fig. 2, both ends of the braided wire 110 are provided with a rounded structure 111, and the radial dimension of the rounded structure 111 is not smaller than the wire diameter of the braided wire 110. In one embodiment, the difference between the radial dimension of the rounded structure 111 and the wire diameter of the braided wire 110 is not greater than 0.02mm. In one embodiment, the rounded structure 111 is a ball or sphere-like structure formed by hot-melting the ends of the braided filaments 110. In another embodiment, the rounded structure 111 is a ball or sphere-like structure formed by wrapping the ends of the braided wires 110 with glue. In another embodiment, the rounded structure 111 may be a ball or sphere-like structure formed by hot melting of the developing metal at the end of the knitting yarn.
It should be noted that the term "sphere-like structure" in the present application refers to a sphere-like structure similar to a sphere structure, but is not limited to a sphere structure in a strict sense, such as an ellipsoidal structure.
By arranging the smooth structure 111 at the end of the braided wire 110, the situation that the end face of the braided wire 110 of the blood flow guiding stent 100 is too sharp can be avoided, so that pushing of the braided wire in a microcatheter is smoother, the stimulation of the blood flow guiding stent 100 to the vascular wall can be reduced, and the probability of thrombus occurrence and stent internal stenosis is reduced.
Referring to fig. 3, the delivery device 200 includes a delivery guidewire 210 and a push rod 220 connected to the delivery guidewire 210, wherein a proximal end of the delivery guidewire 210 is fixedly connected to a distal end of the push rod 220, for example, by welding or the like.
In one embodiment, the delivery guidewire 210 is nickel titanium alloy or stainless steel. The delivery guidewire 210 employs a tapered wire, with the diameter of the delivery guidewire 210 gradually decreasing from the proximal end to the distal end. In one embodiment, the diameter of the larger diameter end of the delivery guidewire 210 is 0.1mm-0.2mm and the diameter of the smaller diameter end is 0.03mm-0.1mm.
With continued reference to fig. 3, the delivery device 200 further includes a spring coil 230, wherein the spring coil 230 is fixedly disposed at the distal end of the delivery guidewire 210, i.e., the spring coil 230 is disposed around the smaller diameter end of the delivery guidewire 210. In one embodiment, the spring coil 230 is fixed to the distal-most end of the delivery guidewire 210 by welding, soldering, or bonding with a polymer biocompatible material, and the distal end of the spring coil 230 is hemispherical to prevent the distal end of the delivery guidewire 210 from being too sharp and damaging the vessel wall. During release of the blood flow guiding stent 100 from the microcatheter, the spring coil 230 may act as a buffer to reduce the force exerted by the head end of the delivery guidewire 210 against the vessel wall and prevent damage to the vessel wall.
Referring to fig. 3 and 4, the spring coil 230 includes a developing portion 231 and a non-developing portion 232, and the developing portion 231 and the non-developing portion 232 are butted together by welding or bonding to form the spring coil 230. Wherein the developing portion 231 is closer to the distal end of the delivery guidewire 210 than the non-developing portion 232. The developing part 231 may be wound with a braided wire having a relatively high density, such as platinum, gold, tantalum, platinum tungsten alloy, platinum iridium alloy, etc., and the wire used has a good developing property under DSA (digital subtraction angiography). The wire diameter of the wire wound around the developing portion 231 is 0.01mm to 0.1mm, and the diameter of the developing portion 231 is 0.1mm to 0.5mm. The non-developing portion 232 may be wound from a relatively small density wire such as stainless steel, and the wire used for the non-developing portion 232 is not substantially developed under DSA. The wire diameter of the wire used for winding the non-development portion 232 is 0.01mm to 0.1mm, and the diameter of the non-development portion 232 is 0.1mm to 0.5mm. In one embodiment, the total length of the spring coil 230 is 5mm-30mm, wherein the ratio of the lengths of the developing portion 231 and the non-developing portion 232 may be 1:1. Of course, in other embodiments, the length ratio of the developing portion 231 to the non-developing portion 232 may be other values as long as the length of the non-developing portion 232 is ensured to be not less than 2mm.
With continued reference to fig. 3 and 4, the delivery device 200 further includes a distal development point 240, the distal development point 240 being secured to the proximal ends of the delivery guidewire 210 and the spring coil 230, such as by welding. In one embodiment, the material of the distal development points 240 may be a metal with a high density such as platinum, gold, tantalum, etc. and good development under DSA. In an embodiment, the two ends of the distal developing point 240 are tapered, the middle portion is cylindrical, the diameter of the middle portion is the same as the diameter of the spring coil 230, the length is 0.5mm-1mm, the taper angles of the two ends are 30 ° -60 °, the distal tapered structure can facilitate welding and positioning of the distal developing point 240 and the spring coil 230, and the proximal tapered structure can facilitate recovery of the delivery guide wire 210 to the microcatheter without jamming. Referring to fig. 9, the function of the distal development point 240 is to determine whether the distal end of the blood flow guiding stent 100 is pushed out of the micro-catheter 400, and when the distal development point 240 coincides with the development ring 401 at the distal end of the micro-catheter 400, it indicates that the distal end of the blood flow guiding stent 100 has been pushed out of the micro-catheter 400.
Referring to fig. 3, 5 and 6, the delivery guidewire 210 is provided with an anti-slip ring 250 and a resilient gasket 260. The anti-drop ring 250 is sleeved on the delivery guide wire 210 and is fixedly connected with the delivery guide wire 210. The elastic washer 260 is slidably disposed over the delivery guidewire 210, and the proximal end of the blood flow guiding stent 100 is sleeved over the elastic washer 260. The proximal end of the anti-slip ring 250 abuts the distal end of the resilient washer 260 and the proximal end of the anti-slip ring 250 can be inserted into the gap between the resilient washer 260 and the delivery guidewire 210 to increase the radial dimension of the distal end of the resilient washer 260.
When the blood flow guiding stent 100 needs to be withdrawn in the micro catheter 400, a certain friction force between the elastic washer 260 and the blood flow guiding stent 100 does not cause relative sliding at once, but the elastic washer 260 can slide on the delivery guiding wire 210, so that when the delivery guiding wire 210 is withdrawn, relative movement between the elastic washer 260 and the blood flow guiding stent 100 occurs, the anti-drop ring 250 is fixed on the delivery guiding wire 210, the anti-drop ring 250 moves together with the delivery guiding wire 210, at the moment, the proximal end of the anti-drop ring 250 is embedded into the gap between the delivery guiding wire 210 and the elastic washer 260, the radial dimension of the distal end of the elastic washer 260 can be increased by the anti-drop ring 250, so that the mutual pressure between the elastic washer 260 and the blood flow guiding stent 100 is increased, the relative movement between the elastic washer 260 and the blood flow guiding stent 100 can not occur, and the proximal end of the blood flow guiding stent 100 can be prevented from being separated from the elastic washer 260.
Referring to fig. 6 and 7, the anti-drop ring 250 includes a main body 251 and a proximal portion 252 connected to the proximal end of the main body 251, wherein the proximal portion 252 has a tapered structure, and the radial dimension of the proximal portion 252 gradually decreases from the distal end to the proximal end, and the proximal portion 252 can be embedded in the gap between the elastic washer 260 and the delivery guide wire 210. The tapered configuration of proximal portion 252 facilitates insertion of anti-slip ring 250 into the gap between elastomeric washer 260 and delivery guidewire 210. With continued reference to fig. 7, the body portion 251 is cylindrical and has an inner diameter substantially the same as the diameter of the delivery guidewire 210 thereat, or slightly larger than the diameter of the delivery guidewire 210 thereat, and an outer diameter less than or equal to the outer diameter of the resilient washer 260. In one embodiment, the body portion 251 has an inner diameter G of 0.05mm to 0.1mm and an outer diameter E of 0.4mm to 0.6mm. The taper J of the proximal portion 252 is 30-60, and the inner diameter of the proximal portion 252 is the same as the inner diameter of the body portion 251. In one embodiment, the length F of the anti-slip ring 250 is 0.5mm-2mm.
With continued reference to fig. 7, the anti-slip ring 250 further includes a distal portion 253 connected to the distal end of the main body portion 251, wherein the distal portion 253 has a tapered structure, and the radial dimension of the distal portion 253 gradually decreases from the proximal end to the distal end. By designing the distal end 253 into a tapered structure, it is unnecessary to identify which end is tapered during production and assembly, which is advantageous for improving production efficiency. In one embodiment, proximal portion 252 and distal portion 253 are symmetrically designed.
In one embodiment, the anti-slip ring 250 is made of a developing material, such as platinum, tungsten, gold, silver, tantalum, nickel-titanium alloy, cobalt-chromium alloy, platinum-tungsten alloy, or platinum-iridium alloy. The design of the anti-slip ring 250 as a developable structure may help check whether the proximal end of the blood flow guiding stent 100 has been slipped off the elastic washer 260.
In one embodiment, the surface of the anti-slip ring 250 is provided with a hydrophilic coating. For example, a hydrophilic coating material is dip-coated on the surface of the anti-drop ring 250, the hydrophilic coating is normally present in the form of a dry film, and is activated when exposed to water, so that the surface of the anti-drop ring 250 becomes more lubricious, and the anti-drop ring 250 is more easily embedded in the gap between the elastic washer 260 and the delivery guidewire 210 when the delivery guidewire 210 is retracted.
In one embodiment, the elastic gasket 260 has a two-layer structure, the inner layer is a round tube made of polymer, the inner layer can be made of polypropylene, polyimide, etc., and the outer layer is made of silica gel, TPU (thermoplastic polyurethane elastomer) or other elastic polymer materials. In an embodiment, the inner diameter of the elastic washer 260 is larger than the inner diameter of the anti-drop ring 250, i.e., the inner diameter of the inner layer of the elastic washer 260 is larger than the inner diameter of the anti-drop ring 250, so that the anti-drop ring 250 can be conveniently embedded into the gap between the elastic washer 260 and the delivery guide wire 210. In one embodiment, the inner diameter of the inner layer of the elastomeric gasket 260 is 0.16mm-0.25mm, the outer diameter of the inner layer is 0.3mm-0.4mm, the outer diameter of the outer layer is 0.55mm-0.6mm, and the inner diameter of the outer layer is dependent on the outer diameter of the inner layer. In one embodiment, the overall length of the elastomeric gasket 260 is 1mm-5mm, for example, the overall length of the elastomeric gasket 260 is 2mm-3.5mm.
With continued reference to fig. 3, the conveyor 200 further includes a proximal developing ring 270, wherein the proximal developing ring 270 is sleeved on the conveying guide wire 210 and is fixedly connected with the conveying guide wire 210, and the proximal end of the elastic washer 260 abuts against the proximal developing ring 270. In one embodiment, the material of the proximal developing ring 270 is platinum, tungsten, gold, silver, tantalum, nickel-titanium alloy, cobalt-chromium alloy, platinum-tungsten alloy, platinum-iridium alloy, or the like. The proximal developing ring 270 may have a cylindrical structure, the inner diameter of the proximal developing ring 270 is larger than the diameter of the delivery guide wire 210 at the position, and the outer diameter is smaller than the outer diameter of the elastic washer 260, and the proximal developing ring 270 may be fixed to the delivery guide wire 210 by welding or bonding, etc. Referring to fig. 9, the proximal developing ring 270 is used to determine whether the blood flow guiding stent 100 is completely pushed out of the micro-catheter 400, and when the proximal developing ring 270 is overlapped with the developing ring 401 at the distal end of the micro-catheter 400, it indicates that the blood flow guiding stent 100 is completely pushed out of the micro-catheter 400.
Referring to fig. 8, the pushing rod 220 includes a distal portion 221 and a proximal portion 222 connected to the distal portion 221, wherein the distal portion 221 is connected to the delivery guidewire 210. In one embodiment, the distal portion 221 is laser engraved using nickel titanium alloy or stainless steel tubing to form a helical hollow, with the pitch of the helix increasing from the distal end to the proximal end. The nickel-titanium alloy or stainless steel tube of the distal end section 221 is also provided with a heat shrinkage tube, such as a PTFE (polytetrafluoroethylene) heat shrinkage tube, which can protect the spiral hollow groove and prevent the distal end section 221 from being straightened due to overlarge stress. The proximal portion 222 includes a nickel-titanium alloy or stainless steel tube integrally formed with the distal portion 221 and a solid steel wire inserted into the nickel-titanium alloy or stainless steel tube, so that the proximal portion 222 has a relatively high supporting strength, and is not easy to be folded during pushing. The pushing rod 220 has better flexibility of the distal section 221, can penetrate through a curved blood vessel, has better supporting force of the proximal section 222, and can realize better pushing effect. In one embodiment, the push rod 220 has an overall length of 1.5m-2.0m, with the distal section 221 having a length of 70mm-120mm. The outer diameter of the push rod 220 is 0.4mm-0.6mm.
Referring to fig. 1, 8 and 9, in use, the blood flow guiding stent 100 is passed through the delivery guidewire 210 of the delivery device 200 such that the distal end of the blood flow guiding stent 100 overlies the non-visualization portion 232, the proximal end of the blood flow guiding stent 100 overlies the elastomeric grommet 260 and extends to the proximal visualization ring 270, and then is loaded together into the introducer sheath 300. The introducer sheath 300 is inserted into the microcatheter 400, the inner diameter of the microcatheter 400 is the same as the inner diameter of the lumen of the introducer sheath 100, the push conveyor 200 is pushed into the microcatheter 400 along with the blood flow guiding stent 100 (when the microcatheter 400 has reached the lesion site), the push conveyor 200 is continued with the distal visualization point beyond the visualization ring 401 at the distal end of the microcatheter 400, when the distal end 240 of the blood flow guiding stent 100 has pushed out of the microcatheter 400, the push conveyor 200 is continued with the proximal visualization ring 270 beyond the visualization ring 401 at the distal end of the microcatheter 400, and when the blood flow guiding stent 100 has all been pushed out of the microcatheter 400 and released within the blood vessel. Finally, the transporter 200 and the microcatheter 400 are withdrawn to complete the surgical procedure.
If the release of the position of the blood flow guiding stent 100 is found to be inappropriate when the anti-slip ring 250 does not extend beyond the developing ring 401 at the distal end of the micro catheter 400, the delivery guidewire 210 may be retracted to pull the blood flow guiding stent 100 back into the micro catheter 400. When the blood flow guiding stent is retracted, because a certain friction force between the elastic gasket 260 and the blood flow guiding stent 100 does not slide relatively immediately, and the elastic gasket 260 can slide on the conveying guide wire 210, when the conveying guide wire 210 is retracted, the elastic gasket 260 moves relatively, the anti-falling ring 250 is fixed on the conveying guide wire 210, the anti-falling ring 250 moves together with the conveying guide wire 210, at the moment, the proximal end of the anti-falling ring 250 is embedded into a gap between the conveying guide wire 210 and the elastic gasket 260, the radial dimension of the distal end of the elastic gasket 260 can be increased by the anti-falling ring 250, so that the mutual pressure between the elastic gasket 260 and the blood flow guiding stent 100 is increased, the elastic gasket 260 and the blood flow guiding stent 100 cannot move relatively, and the proximal end of the blood flow guiding stent 100 can be prevented from being separated from the elastic gasket 260.
The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The above examples illustrate only a few embodiments of the invention, which are described in detail and are not to be construed as limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.
Claims (10)
1. A conveyor for conveying a blood flow guiding stent, comprising:
the guide wire is conveyed and guided,
the elastic gasket is arranged on the conveying guide wire in a sliding manner, and the proximal end of the blood flow guiding bracket is sleeved on the elastic gasket; and
The anti-drop ring is sleeved on the conveying guide wire, the proximal end of the anti-drop ring is abutted to the distal end of the elastic gasket, and the proximal end of the anti-drop ring can be embedded into a gap between the elastic gasket and the conveying guide wire, so that the radial size of the distal end of the elastic gasket is increased.
2. The delivery device of claim 1, wherein the anti-slip ring comprises a body portion and a proximal portion connected to a proximal end of the body portion, the proximal portion having a tapered configuration, and the proximal portion having a radial dimension that decreases from distal to proximal, the proximal portion being capable of being inserted into a gap between the elastomeric washer and the delivery guidewire.
3. The conveyor of claim 2, wherein the proximal end portion has a taper angle of 30 ° -60 °.
4. The conveyor of claim 2, wherein the slip-off prevention ring further comprises a distal portion connected to the distal end of the main body portion, the distal portion having a tapered configuration, and the radial dimension of the distal portion gradually decreasing from the proximal end to the distal end.
5. The conveyor of claim 1, wherein the slip-off prevention ring is made of a developing material.
6. The conveyor of claim 1, wherein the slip-off prevention surface is provided with a hydrophilic coating.
7. The conveyor of claim 1, further comprising a proximal development ring, wherein the proximal development ring is sleeved on the delivery guidewire and fixedly connected to the delivery guidewire, and wherein the proximal end of the elastic washer abuts the proximal development ring.
8. The conveyor of claim 1, wherein the inner diameter of the resilient gasket is greater than the inner diameter of the anti-slip ring.
9. The delivery device of claim 1, further comprising a spring coil fixedly disposed at a distal end of the delivery guidewire.
10. A blood flow guiding stent system comprising the transporter of any one of claims 1-9, further comprising a blood flow guiding stent, wherein the blood flow guiding stent is sleeved on the delivery guidewire, and wherein the proximal end of the blood flow guiding stent is positioned on the elastic washer.
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CN202311804068.0A CN117796976A (en) | 2023-12-25 | 2023-12-25 | Conveyor and blood flow guiding bracket system |
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CN202311804068.0A CN117796976A (en) | 2023-12-25 | 2023-12-25 | Conveyor and blood flow guiding bracket system |
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