CN117771461A - High-efficient filtration oxygenator - Google Patents

Abstract

The invention provides a high-efficiency filtering oxygenator which comprises a shell and an oxygenation temperature changing module, wherein the bottom of the shell is provided with a blood inlet, a water inlet and a water outlet, the lower part of the shell is provided with an air outlet and a bleeding port, and the upper part of the shell is provided with an air inlet and an air outlet; the oxygenation alternating temperature module is arranged in the shell and sequentially comprises a drainage component, a variable temperature membrane, a filter screen and an oxygen pressing membrane from inside to outside, wherein the blood inlet end of the drainage component is communicated with the blood inlet, the blood outlet end of the drainage component is positioned at the upper part of the variable temperature membrane, the variable temperature membrane comprises a plurality of variable temperature membrane wires communicated with the water inlet and the water outlet, the oxygen pressing membrane comprises a plurality of oxygen pressing membrane wires communicated with the air inlet and the air outlet, the oxygen pressing membrane wires close to the inner wall of the shell are closely stacked to form a filter structure with a filtering function, and the gap width of the filter structure is smaller than the aperture of the filter screen. The invention can achieve better filtering effect on the premise of not increasing excessive pressure drop and blood pre-charge.

Description

High-efficient filtration oxygenator

Technical Field

The invention relates to the technical field of medical instruments, in particular to a high-efficiency filtering oxygenator.

Background

An extracorporeal circulation device for clinical operation is commonly called artificial lung and is also called oxygenator. The oxygenator plays an important role as a device for in vitro blood oxygenation, in extracorporeal Circulation (CPB) and in extracorporeal membrane lung oxygenation (ECMO). In the application process, the main function of the device is to convert oxygen-deficient venous blood into oxygen-enriched arterial blood to replace the lung function so as to meet the needs of patients in operation.

Because the leading-out blood contains the emboli including bubbles and solid particles, the direct reinfusion of the human body can cause vascular embolism, so that in the extracorporeal circulation, besides the oxygenator is adopted to exchange gas for the blood to maintain the oxygen supply of a patient, a filter is used for intercepting the emboli in the blood, and the filter is a safety barrier for reinfusion of the blood to the human body. In the prior art, a filter and an oxygenator are integrated into a whole, for example, in an oxygenator structure with blood flowing from inside to outside, the filter is a filter screen wrapping the outermost wire membrane of the oxygenator, and in an oxygenator structure with blood flowing from outside to inside, the filter is a filter screen wrapping the innermost wire membrane of the oxygenator.

However, in the structure of the oxygenator with the blood flowing from outside to inside, in order to meet the filtering requirement, the inner space of the oxygenator is usually made large, so that a filter screen with a large enough area is installed, but the design enlarges the volume of the oxygenator, increases the blood pre-charge amount, and is not suitable for the oxygenator used for infants. For the structure of the oxygenator with blood flowing outwards from inside to outside, the area of the filter screen is increased, and the volume of the oxygenator is not required to be enlarged intentionally. However, in the oxygenator for the inside-out or outside-in of blood, because the sizes of bubbles and particles mixed in the blood are different, in order to meet the filtration requirement, the mesh of the filter screen is usually designed to be small, so that poor blood passing performance is caused, the pressure loss of the blood is rapidly increased when the blood flows through the filter screen, the maximum output capacity of the blood pump and the rotating speed difference under the flow rate are determined by the pressure loss of the oxygenator, the blood pump is required to maintain the flow rate at a larger rotating speed when the pressure loss of the oxygenator is larger, so that the blood damage is aggravated, meanwhile, the contact time between the blood and an oxygen pressure film wire is shortened due to the increase of the blood flow rate, the oxygenation efficiency is reduced, the large bubbles are scattered into small bubbles due to the increase of the blood flow rate, and the passing performance of the blood at the filter screen is further weakened due to the increase of the small bubbles. In view of the above, it is necessary to design an oxygenator with small pre-charge, small pressure loss and good filtering effect to meet the functional needs in critical emergency situations.

Disclosure of Invention

Aiming at the defects existing in the prior art, the invention aims to provide the high-efficiency filter oxygenator, which can achieve better filtering effect on the premise of not increasing excessive pressure drop, not increasing blood pre-charge or directly reducing the blood pre-charge.

The present disclosure provides a high efficiency filter oxygenator comprising:

the device comprises a shell, wherein the bottom of the shell is provided with a blood inlet, a water inlet and a water outlet, the lower part of the shell is provided with an air outlet and a bleeding port, and the upper part of the shell is provided with an air inlet and an air outlet;

the oxygenation temperature changing module is vertically arranged in the shell and sequentially comprises a drainage component, a temperature changing film, a filter screen and an oxygen pressing film from inside to outside, a blood inlet end of the drainage component is communicated with a blood inlet, a blood outlet end of the drainage component is positioned at the upper part of the temperature changing film, the temperature changing film comprises a plurality of temperature changing film wires communicated with the water inlet and the water outlet, the oxygen pressing film comprises a plurality of oxygen pressing film wires communicated with the air inlet and the air outlet, the oxygen pressing film wires close to the inner wall of the shell are closely stacked to form a filter structure with a filtering function, and the gap width of the filter structure is smaller than the aperture of the filter screen;

blood passes through the drainage component from the blood inlet to the upper part of the variable-temperature membrane, spreads around the drainage component, obliquely passes through the variable-temperature membrane, the filter screen and the oxygen pressing membrane from top to bottom, and then flows out from the blood outlet, and gas in the shell can be discharged through the exhaust port.

Optionally, the arrangement density of the oxygen pressed film wires close to the inner wall of the shell is greater than the arrangement density of the oxygen pressed film wires close to the filter screen.

Optionally, the filtration includes from inside to outside the multilayer membrane silk group of arranging, and the membrane silk group parcel that is located the inlayer is located the membrane silk group of outer membrane silk group, and every layer membrane silk group includes the many oxygen pressure membrane silk of interval arrangement, and the oxygen pressure membrane silk in two adjacent layers membrane silk groups staggers the setting.

Optionally, oxygen film pressing wires in the film wire group are vertically arranged in the shell, and the number of the film wire groups in the filtering structure is 6-10 layers.

Optionally, the gaps between adjacent oxygen film pressing wires in the film wire group are 0.1-0.3 times of the diameters of the oxygen film pressing wires.

Optionally, the aperture of the filter screen is 70-100 μm; the gap width of the filter structure is not more than 40 μm.

Optionally, the ratio of the outer diameter of the oxygen compression film to the effective contact height of the oxygen compression film is 1:1-2:1.

Optionally, the drainage subassembly includes the drainage tube, be equipped with first drainage mouth and second drainage mouth on the drainage tube, first drainage mouth intercommunication advance the blood mouth, the second drainage mouth is located the upper portion of alternating temperature membrane, first drainage mouth constitutes the blood inlet of drainage subassembly holds, the second drainage mouth constitutes the bleeding end of drainage subassembly.

Optionally, the first drainage port is arranged at the lower end of the drainage tube, and the second drainage port is arranged at the upper end of the drainage tube and/or on the tube wall at the upper part of the drainage tube;

when the second drainage openings are arranged on the pipe wall of the drainage pipe, the second drainage openings are uniformly distributed along the circumferential direction of the pipe wall.

Optionally, the drainage assembly further comprises a mandrel arranged in the drainage tube, a flow passage is arranged between the mandrel and the inner wall of the drainage tube, and the first drainage port is communicated with the second drainage port through the flow passage.

Optionally, the upper end of dabber with the upper portion fixed connection of drainage tube, the lower extreme of dabber extends to first drainage mouth, the diameter of dabber is from being close to one side of second drainage mouth to being close to one side of first drainage mouth reduces.

Optionally, the exhaust port is disposed on the housing at a position higher than an effective contact height of the oxygen compression film.

Optionally, the oxygenator further comprises a first blocking layer and a second blocking layer which are arranged in the shell, wherein the first blocking layer is positioned at the top of the oxygenation temperature changing module, and the second blocking layer is positioned at the bottom of the oxygenation temperature changing module;

the drainage assembly penetrates through the second blocking layer to be communicated with the blood inlet, the variable-temperature membrane surrounds the drainage assembly, an inlet of the variable-temperature membrane wire penetrates through the second blocking layer to be communicated with the water inlet, an outlet of the variable-temperature membrane wire penetrates through the second blocking layer to be communicated with the water outlet, the filter screen wraps the variable-temperature membrane, the oxygen pressing membrane surrounds the filter screen, an inlet of the oxygen pressing membrane wire penetrates through the first blocking layer to be communicated with the air inlet, and an outlet of the oxygen pressing membrane wire penetrates through the second blocking layer to be communicated with the air outlet.

Optionally, the shell comprises a shell body, an upper cover arranged at an opening at the top of the shell body and a lower cover arranged at an opening at the bottom of the shell body, the air inlet is arranged on the upper cover, the blood inlet, the air outlet, the water inlet and the water outlet are arranged on the lower cover, the air outlet is arranged at a position on the shell body close to the upper cover, and the blood outlet is arranged at a position on the shell body close to the lower cover;

the oxygenation temperature changing module is arranged in the shell body, the first blocking layer is arranged between the upper end of the oxygenation temperature changing module and the upper cover, and the second blocking layer is arranged between the lower end of the oxygenator module and the lower cover.

By implementing the scheme, the method has the following beneficial effects:

the utility model discloses a set up filter screen and filtration, increased the filtration area of oxygenator, can realize better filter effect. And moreover, the oxygen pressed film wires are closely stacked to form the filter structure, so that an additional space is not required to be added to accommodate the filter structure, and the filter screen is not required to be made into a corrugated shape which occupies a larger space, so that the occupation of the inner space of the oxygenator is not increased, and the blood pre-charge amount can be reduced.

The blood inlet is formed in the bottom of the oxygenator, the bleeding port is formed in the lower portion of the oxygenator, the drainage component drains blood from the blood inlet to the upper portion of the oxygenator, when the blood diffuses to the periphery, the blood obliquely penetrates through the temperature changing membrane, the filter screen and the oxygen pressing membrane from top to bottom, and then flows out of the bleeding port in the lower portion. In the blood path design, blood flows from the upper part of the oxygenator from top to bottom, the blood flow speed is increased, and even if a filter screen and a filter structure are added on the basis of a temperature changing film and an oxygen pressure film, the pressure loss is not increased greatly; and the aperture of the filter screen is larger than the gap width of the filter structure, the resistance of the filter screen is smaller than the resistance of the filter structure, and blood passes through the filter screen and then the filter structure, so that the blood trafficability is not obviously weakened. In addition, to the oxygenator structure that only sets up the filter screen in the oxygen press film outside, because mix large granule impurity and bubble in the blood, can cause the blood to pass through the oxygen press film and pass through the nature when reducing to impurity and the bubble of different granularity reach the filter screen, in order to satisfy the filtration requirement, have to make the filter screen aperture small, this also objectively reduces the trafficability of blood in filter screen department. This disclosure intercepts great bubble and impurity in the alternating temperature membrane side through the filter screen, can improve the trafficability characteristic when blood passes through oxygen pressure membrane, reduces outside filtration's filtration pressure, makes the trafficability characteristic of blood in filtration department improve.

In a word, the invention can achieve better filtering effect on the premise of not increasing excessive pressure drop and blood pre-charge.

Drawings

FIG. 1 is a schematic illustration of the structure of a high efficiency filter oxygenator of the present disclosure;

FIG. 2 is a cross-sectional view of the disclosed high efficiency filter oxygenator;

FIG. 3 is a schematic blood flow diagram of the high efficiency filter oxygenator of the present disclosure;

FIG. 4 is a schematic view of the gas circuit of the high efficiency filter oxygenator of the present disclosure;

FIG. 5 is a schematic view of the waterway of the high efficiency filter oxygenator of the present disclosure;

FIG. 6 is a schematic illustration of the structure of a drainage assembly of the disclosed high efficiency filter oxygenator;

FIG. 7 is a cross-sectional view of a drainage assembly of the high efficiency filter oxygenator of the present disclosure;

FIG. 8 is a schematic cross-sectional view of a filter structure of the disclosed high efficiency filter oxygenator;

fig. 9 is a schematic view of the structure of the filter structure of the high efficiency filter oxygenator disclosed in the present invention.

In the figure:

100 outer shell, 101 shell, 102 upper cover, 103 lower cover, 104 blood inlet, 105 blood outlet, 106 water inlet, 107 water outlet, 108 air inlet, 109 air outlet, 110 air outlet,

200 oxygenation temperature changing module, 201 temperature changing film, 202 filter screen, 203 oxygen film pressing, 204 filter structure, 205 drainage component, 206 drainage tube, 207 first drainage port, 208 second drainage port, 209 mandrel, 211 film wire group, 212 oxygen film pressing wire, 213 gap,

300 a first blocking layer of the polymer film,

400 second blocking layer.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. The components of the embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.

In the description of the present invention, it should be noted that, directions or positional relationships indicated by terms such as "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., are directions or positional relationships based on those shown in the drawings, or are directions or positional relationships conventionally put in use of the inventive product, are merely for convenience of describing the present invention and simplifying the description, and are not indicative or implying that the apparatus or element to be referred to must have a specific direction, be configured and operated in a specific direction, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used merely to distinguish between descriptions and should not be construed as indicating or implying relative importance. In the description of the present invention, unless otherwise indicated, the meaning of "a plurality" is two or more.

In the description of the present invention, it should also be noted that, unless explicitly specified and limited otherwise, the terms "disposed", "connected" and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected or integrally connected; either mechanically or electrically. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.

In the present invention, unless expressly stated or limited otherwise, a first feature "above" or "below" a second feature may include both the first and second features being in direct contact, as well as the first and second features not being in direct contact but being in contact with each other through additional features therebetween. Moreover, a first feature being "above," "over" and "on" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly under and obliquely below the second feature, or simply means that the first feature is less level than the second feature.

Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative only and are not to be construed as limiting the invention.

The embodiment provides a high-efficiency filtering oxygenator, which comprises a shell 100 and an oxygenation temperature changing module 200 arranged in the shell 100. Referring to fig. 1-5, the housing 100 is cylindrical, a blood inlet 104, a water inlet 106 and a water outlet 107 are provided at the bottom of the housing 100, an air outlet 109 and a bleeding port 105 are provided at the lower part of the housing 100, and an air inlet 108 and an air outlet 110 are provided at the upper part. The oxygenation temperature changing module 200 is vertically arranged in the shell 100, the oxygenation temperature changing module 200 sequentially comprises a drainage assembly 205, a temperature changing film 201, a filter screen 202 and an oxygen pressing film 203 from inside to outside, a blood inlet end of the drainage assembly 205 is communicated with a blood inlet 104, a blood outlet end of the drainage assembly is located at the upper part of the temperature changing film 201, the temperature changing film 201 comprises a plurality of temperature changing film wires communicated with a water inlet 106 and a water outlet 107, the oxygen pressing film 203 comprises a plurality of oxygen pressing film wires 212 communicated with a gas inlet 108 and a gas outlet 109, the oxygen pressing film wires 212 close to the inner wall of the shell 100 are closely stacked to form a filter structure 204 with a filtering function, and a gap 213 width of the filter structure 204 is smaller than the aperture of the filter screen 202. Wherein, close-packed refers to a plurality of oxygen pressed film filaments 212 being closely stacked along their long axes. When in use, blood reaches the upper part of the temperature changing membrane 201 from the blood inlet 104 through the drainage component 205, spreads around the drainage component 205, and flows out from the bleeding port 105 after passing through the temperature changing membrane 201, the filter screen 202 and the oxygen compression membrane 203 from top to bottom in an inclined manner, and the gas in the shell 100 can be discharged through the gas outlet 110.

Referring to fig. 2, the oxygenator further includes a first blocking layer 300 and a second blocking layer 400 disposed in the housing 100, wherein the first blocking layer 300 is disposed at the top of the oxygenation temperature changing module 200, and the second blocking layer 400 is disposed at the bottom of the oxygenation temperature changing module 200. The drainage assembly 205 passes through the second blocking layer 400 to be communicated with the blood inlet 104, the variable temperature membrane 201 is arranged around the drainage assembly 205, the inlet of the variable temperature membrane wire passes through the second blocking layer 400 to be communicated with the water inlet 106, the outlet passes through the second blocking layer 400 to be communicated with the water outlet 107, the filter screen 202 wraps the variable temperature membrane 201, the oxygen pressure membrane 203 is arranged around the filter screen 202, the inlet of the oxygen pressure membrane wire 212 passes through the first blocking layer 300 to be communicated with the air inlet 108, and the outlet passes through the second blocking layer 400 to be communicated with the air outlet 109. In one possible implementation, temperature changing membrane 201 wraps drainage assembly 205, filter mesh 202 wraps temperature changing membrane 201, and oxygen compression membrane 203 wraps filter mesh 202, which reduces the space between the components, reduces the need for space within housing 100, and thus reduces the blood pre-load.

The filter screen 202 may be a filter screen 202 with a planar structure, or may be a filter screen 202 with a pleated structure, which of course, the filter screen 202 with a planar structure can reduce space occupation, thereby being beneficial to reducing blood pre-charge, while the filter screen 202 with a pleated structure can increase the filter area, thereby improving the filter effect, and can be used alternatively or in combination according to the needs when in application.

In the conventional oxygen pressure membrane structure, in order to ensure the passing rate of blood in the oxygen pressure membrane 203 and reduce the pressure loss, the gap between the adjacent oxygen pressure membrane wires 212 is about 1.2 times the diameter of the oxygen pressure membrane wires 212, and large-diameter particles and bubbles easily pass through the gap between the oxygen pressure membrane wires 212, so that the conventional oxygen pressure membrane structure has no filtering function. In this embodiment, the oxygen compression film 203 is structurally improved, specifically, the arrangement density of oxygen compression film wires 212 near the inner wall of the casing 100 is greater than that of oxygen compression film wires 212 near the filter screen 202, the oxygen compression film wires 212 near the inner wall of the casing 100 are closely stacked to form a filter structure 204 with a filtering function, and the width of a gap 213 of the filter structure 204 is smaller than the aperture of the filter screen 202, so that smaller particles and bubbles escaping from the filter screen 202 can be intercepted. Because the arrangement density of the oxygen compression film wires 212 near the filter screen 202 is smaller, the passing rate of blood at the position of the oxygen compression film 203 near the filter screen 202 is better, the pressure loss is smaller, and the condition that the pressure loss is increased sharply when the blood reaches the oxygen compression film 203 is avoided.

Referring to fig. 8 and 9, the filtering structure 204 includes a plurality of film yarn groups 211 arranged from inside to outside, the film yarn groups 211 located at the outer layer wrap the film yarn groups 211 located at the inner layer, each film yarn group 211 includes a plurality of oxygen compression film yarns 212 arranged at intervals, the oxygen compression film yarns 212 in two adjacent film yarn groups 211 are staggered along the length direction of the oxygen compression film yarns 212, and the length directions of the oxygen compression film yarns 212 are consistent; as shown in fig. 8, the filter structure 204 is honeycomb in cross-section of the oxygenator. In one possible implementation manner, the oxygen film pressing wires 212 in the film wire group 211 are vertically arranged in the shell 100, the number of the film wire groups 211 in the filtering structure 204 is 6-10 layers, and particles and bubbles are intercepted through the multi-layer structure, so that escape probability of the particles and the bubbles can be reduced. Gaps 213 between adjacent oxygen film pressing wires 212 in the film wire group 211 are 0.1-0.3 times of the diameter of the oxygen film pressing wires 212, the gaps 213 are smaller than or equal to 40 mu m, and particles and bubbles with diameters larger than 40 mu m are not allowed to pass through; illustratively, the gaps 213 between adjacent oxygen tension filaments 212 in the filament set 211 may be 0.2 times the diameter of the oxygen tension filaments 212.

The temperature changing film wires of the temperature changing film 201 are distributed along the long axis of the mandrel 209, and an overflow gap is formed between the adjacent temperature changing film wires, and a plurality of overflow gaps form a shutter shape in the radial direction of the oxygenator. The oxygen pressure film 203 wraps the temperature changing film 201, the oxygen pressure film 203 comprises an oxygen pressure film main body wrapping the filter screen 202 and a filter structure 204 wrapping the oxygen pressure film main body, wherein oxygen pressure film wires 212 of the oxygen pressure film main body are distributed along the long axis of a mandrel 209 and are mutually staggered, through-flow holes are formed between adjacent oxygen pressure film wires 212, and a plurality of through-flow holes form a honeycomb shape in the radial direction of the oxygenator. After the blood flows out transversely from the bleeding end of the drainage assembly 205, the blood is switched to flow obliquely downwards under the influence of gravity and the influence of external membrane wires, so that the blood obliquely passes through the overflow gaps between the variable-temperature membrane wires. The flow direction of the blood passing through the oxygen compression membrane 203 obliquely is similar to a step shape, and can be decomposed into two states of crossing the flow hole and flowing along the oxygen compression membrane wire 212. Specifically, since the flow gap is a long channel and the flow through hole is a hole channel, the blood is blocked by the oxygen pressure film wire 212 after passing through the flow gap, the flow direction is changed from the oblique downward direction to the transverse direction, and the blood traverses the flow through hole near the temperature changing film 201, then the blood flows downwards along the oxygen pressure film wire 212 under the driving of the continuously injected blood, traverses the flow through hole of the oxygen pressure film wire 212 near the inner wall of the shell 100 in the oxygen pressure film main body, reaches the filter structure 204, passes through the gap 213 of the filter structure 204, and flows out from the bleeding nozzle. The term "across" means that the blood passes through the through-flow hole in a manner of passing through the through-flow hole vertically, that is, the blood flows along the radial direction of the oxygenator, and in this state, the blood receives little resistance, flows fast, and the blood receives little damage.

In one possible implementation, referring to fig. 1, the housing 100 may include a housing body 101, an upper cover 102 and a lower cover 103, where the top and bottom of the housing body 101 are open, the upper cover 102 is disposed at the top opening of the housing body 101, and the lower cover 103 is disposed at the bottom opening of the housing body 101. The blood inlet 104, the air outlet 109, the water inlet 106 and the water outlet 107 are arranged on the lower cover 103, the air outlet 110 is arranged on the shell 101 at a position close to the upper cover 102, and the bleeding opening 105 is arranged on the shell 101 at a position close to the lower cover 103. The oxygenation temperature changing module 200 is disposed in the shell 101, the first blocking layer 300 is disposed between the upper end of the oxygenation temperature changing module 200 and the upper cover 102, and the second blocking layer 400 is disposed between the lower end of the oxygenator module and the lower cover 103.

In one possible implementation, the oxygenation temperature swing module 200 is cylindrical and the ratio of the outer diameter of the oxygen compression film 203 to the effective contact height of the oxygen compression film 203 is 1:1 to 2:1. The effective contact height of the oxygen compression film 203 refers to the height of the portion of the oxygen compression film 203 within the housing 101 that can convert oxygen-depleted blood into oxygen-enriched blood, without exceeding the exhaust port 110. The effective contact height of the oxygen compression film 203 may specifically be the distance between the top surface of the second blocking layer 400 and the lower end surface of the exhaust port 110.

Referring to fig. 2, the exhaust port 110 communicates with the oxygen compression film 203 and is higher than the effective contact height of the oxygen compression film 203. Bubbles floating up to the blood level may be discharged through the vent 110, but the blood flows obliquely downward without flowing out of the vent 110. The bleeding port 105 is arranged at the lower part of the oxygenator, the exhaust port 110 is arranged at the upper part of the oxygenator, blood flows obliquely downwards, and bubbles with lighter mass float upwards, so that the separation of bubbles in the blood is facilitated, and the bubble removal effect is better.

In one possible implementation, the filter 202 has a pore size of 70 μm to 100 μm for intercepting larger diameter particles and bubbles in blood. The gap 213 of the filter structure 204 is not greater than 40 μm, for example, 38 μm, and the filter structure 204 is used to intercept small diameter particles and bubbles in blood. According to the method, two-stage filtration of blood is realized by arranging the filter screen 202 and the filter structure 204, when the blood obliquely passes through the temperature changing membrane 201 and the oxygen pressing membrane 203, particles and bubbles with larger diameters are filtered, only the blood and the particles and bubbles with smaller diameters contained in the particles and bubbles are allowed to reach the oxygen pressing membrane 203, and the reduction of the particles and the bubbles enables the blood to be in better contact with the oxygen pressing membrane 203, so that the oxygenation effect can be improved; the reduction of particulate matter and air bubbles in the blood also reduces the filtering pressure of the outer filtering structure 204, and can improve the filtering effect of the filtering structure 204.

Referring to fig. 2 and 6, the drainage assembly 205 may include a drainage tube 206, where a first drainage port 207 and a second drainage port 208 are disposed on the drainage tube 206, the first drainage port 207 is communicated with the blood inlet 104, and the second drainage port 208 is located on the upper portion of the temperature changing film 201. The first drainage port 207 forms a blood inlet end of the drainage assembly 205 and the second drainage port 208 forms a blood outlet end of the drainage assembly 205. Wherein, the first drainage port 207 is arranged at the lower end of the drainage tube 206, and the second drainage port 208 is arranged at the upper end of the drainage tube 206 and/or on the tube wall at the upper part of the drainage tube 206. In a possible implementation manner, the second drainage ports 208 are arranged on the pipe wall of the drainage pipe 206, and the second drainage ports 208 are uniformly distributed along the circumferential direction of the pipe wall, so that the blood entering the drainage pipe 206 can be dispersed and flows out to the periphery of the drainage pipe 206, the blood is ensured to be fully contacted with the oxygen pressure film 203, and the utilization rate of the oxygen pressure film 203 is improved.

Referring to fig. 7, the drainage assembly 205 may further include a mandrel 209, where the mandrel 209 is disposed in the drainage tube 206, and an overflow channel is disposed between the mandrel 209 and an inner wall of the drainage tube 206, and the first drainage port 207 is in communication with the second drainage port 208 through the overflow channel. The upper end of the mandrel 209 is fixedly connected with the upper part of the drainage tube 206, the lower end of the mandrel 209 extends towards the first drainage port 207, and the diameter of the mandrel 209 decreases from the side close to the second drainage port 208 to the side close to the first drainage port 207. In this embodiment, the core shaft 209 plays a role in dispersing blood, and the blood enters the drainage tube 206 from the blood inlet 104, is blocked by the core shaft 209, disperses to the periphery, then reaches the second drainage port 208 along the flow passage, flows out from the second drainage port 208 in circumferential arrangement, and achieves the effect of uniformly dispersing from the periphery of the drainage assembly 205 to the temperature changing film 201.

The embodiment can achieve better filtering effect on the premise of not increasing excessive pressure drop and blood pre-charge, and the specific analysis is as follows:

first, the blood from the blood inlet 104 is drained to the upper part of the oxygenator by the drainage component 205, and when the blood is diffused all around, the blood obliquely passes through the temperature changing membrane 201, the filter screen 202 and the oxygen pressing membrane 203 from top to bottom, and then flows out from the lower bleeding opening 105. In the blood path design, blood flows from the upper part of the oxygenator from top to bottom, the blood flow speed is increased, and even if the filter screen 202 and the filter structure 204 are added on the basis of the temperature changing film 201 and the oxygen pressure film 203, the pressure loss is not increased greatly; and the pore size of the filter screen 202 is larger than the width of the gap 213 of the filter structure 204, the resistance of the filter screen 202 is smaller than the resistance of the filter structure 204, and the blood passes through the filter screen 202 and then through the filter structure 204, so that the blood passing performance is not obviously weakened.

Second, large bubbles and impurities are intercepted on the temperature changing membrane 201 side by the filter screen 202, so that the passing performance of blood through the oxygen pressure membrane 203 can be improved, the filter pressure of the outer filter structure 204 can be reduced, and the passing performance of blood at the filter structure 204 can be improved.

Third, the filter screen 202 and the filter structure 204 increase the filter area of the oxygenator, so that a better filter effect can be achieved. In addition, the oxygen compression wires 212 are closely stacked to form the filter structure 204, so that no additional space is required to accommodate the filter structure 204, and the filter screen 202 does not need to be in a corrugated shape with a large occupied space, so that the occupation of the internal space of the oxygenator is not increased, and the blood pre-charge amount can be reduced.

Note that the above is only a preferred embodiment of the present invention and the technical principle applied. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, while the invention has been described in connection with the above embodiments, the invention is not limited to the embodiments, but may be embodied in many other equivalent forms without departing from the spirit or scope of the invention, which is set forth in the following claims.

Claims (14)

1. A high efficiency filter oxygenator, comprising:

the device comprises a shell (100), wherein a blood inlet (104), a water inlet (106) and a water outlet (107) are formed in the bottom of the shell (100), an air outlet (109) and a bleeding port (105) are formed in the lower portion of the shell (100), and an air inlet (108) and an air outlet (110) are formed in the upper portion of the shell;

the oxygenation temperature changing module (200) is vertically arranged in the shell (100), the oxygenation temperature changing module (200) sequentially comprises a drainage component (205), a temperature changing film (201), a filter screen (202) and an oxygen pressing film (203) from inside to outside, a blood inlet end of the drainage component (205) is communicated with the blood inlet (104), a bleeding end is positioned at the upper part of the temperature changing film (201), the temperature changing film (201) comprises a plurality of temperature changing film wires communicated with the water inlet (106) and the water outlet (107), the oxygen pressing film (203) comprises a plurality of oxygen pressing film wires (212) communicated with the air inlet (108) and the air outlet (109), the oxygen pressing film wires (212) close to the inner wall of the shell (100) are overlapped to form a filter structure (204) with a filtering function, and the width of a gap (213) of the filter structure (204) is smaller than the aperture of the filter screen (202);

blood passes through the drainage assembly (205) from the blood inlet (104) to reach the upper part of the temperature changing membrane (201), diffuses towards the periphery by taking the drainage assembly (205) as the center, obliquely passes through the temperature changing membrane (201), the filter screen (202) and the oxygen pressure membrane (203) from top to bottom and then flows out of the blood outlet (105), and gas in the shell (100) can be discharged through the exhaust port (110).

2. The oxygenator as claimed in claim 1, wherein,

the arrangement density of the oxygen pressed film wires (212) close to the inner wall of the shell (100) is greater than that of the oxygen pressed film wires (212) close to the filter screen (202).

3. The oxygenator as claimed in claim 1, wherein,

the filter structure (204) comprises a plurality of layers of film yarn groups (211) which are arranged from inside to outside, the film yarn groups (211) positioned on the outer layer wrap the film yarn groups (211) positioned on the inner layer, each layer of film yarn group (211) comprises a plurality of oxygen film-pressing yarns (212) which are arranged at intervals, and the oxygen film-pressing yarns (212) in the two adjacent layers of film yarn groups (211) are staggered.

4. The oxygenator as claimed in claim 3, wherein,

oxygen film pressing wires (212) in the film wire group (211) are vertically arranged in the shell (100), and the number of the film wire groups (211) in the filtering structure (204) is 6-10 layers.

5. The oxygenator as claimed in claim 3, wherein,

gaps (213) between adjacent oxygen film pressing wires (212) in the film wire group (211) are 0.1-0.3 times of the diameter of the oxygen film pressing wires (212).

6. The oxygenator as claimed in claim 1, wherein,

the aperture of the filter screen (202) is 70-100 mu m; the gap (213) width of the filter structure (204) is not greater than 40 μm.

7. The oxygenator as claimed in claim 1, wherein,

the ratio of the outer diameter of the oxygen compression film (203) to the effective contact height of the oxygen compression film (203) is 1:1-2:1.

8. The oxygenator as claimed in claim 1, wherein,

the drainage assembly (205) comprises a drainage tube (206), a first drainage port (207) and a second drainage port (208) are arranged on the drainage tube (206), the first drainage port (207) is communicated with the blood inlet (104), the second drainage port (208) is located on the upper portion of the temperature changing membrane (201), the first drainage port (207) is formed into the blood inlet end of the drainage assembly (205), and the second drainage port (208) is formed into the blood outlet end of the drainage assembly (205).

9. The oxygenator as claimed in claim 8, wherein,

the first drainage port (207) is arranged at the lower end of the drainage tube (206), and the second drainage port (208) is arranged at the upper end of the drainage tube (206) and/or on the tube wall at the upper part of the drainage tube (206);

when the second drainage ports (208) are arranged on the pipe wall of the drainage pipe (206), the second drainage ports (208) are uniformly distributed along the circumferential direction of the pipe wall.

10. The oxygenator as claimed in claim 8 or 9, wherein,

the drainage assembly (205) further comprises a core shaft (209) arranged in the drainage tube (206), a flow passage is arranged between the core shaft (209) and the inner wall of the drainage tube (206), and the first drainage port (207) is communicated with the second drainage port (208) through the flow passage.

11. The oxygenator as claimed in claim 10, wherein,

the upper end of the mandrel (209) is fixedly connected with the upper part of the drainage tube (206), the lower end of the mandrel (209) extends towards the first drainage port (207), and the diameter of the mandrel (209) decreases from one side close to the second drainage port (208) to one side close to the first drainage port (207).

12. The oxygenator as claimed in claim 1, wherein,

the exhaust port (110) is provided on the housing (100) at a position higher than the effective contact height of the oxygen pressure film (203).

13. The oxygenator as claimed in claim 1, wherein,

the oxygenator further comprises a first blocking layer (300) and a second blocking layer (400) which are arranged in the shell (100), wherein the first blocking layer (300) is positioned at the top of the oxygenation temperature changing module (200), and the second blocking layer (400) is positioned at the bottom of the oxygenation temperature changing module (200);

the drainage assembly (205) passes through the second blocking layer (400) and is communicated with the blood inlet (104), the variable temperature membrane (201) is arranged around the drainage assembly (205), an inlet of the variable temperature membrane wire passes through the second blocking layer (400) and is communicated with the water inlet (106), an outlet of the variable temperature membrane wire passes through the second blocking layer (400) and is communicated with the water outlet (107), the filter screen (202) wraps the variable temperature membrane (201), the oxygen pressing membrane (203) is arranged around the filter screen (202), an inlet of the oxygen pressing membrane wire (212) passes through the first blocking layer (300) and is communicated with the air inlet (108), and an outlet of the oxygen pressing membrane wire passes through the second blocking layer (400) and is communicated with the air outlet (109).

14. The oxygenator as claimed in claim 13, wherein,

the shell (100) comprises a shell body (101), an upper cover (102) arranged at an opening at the top of the shell body (101) and a lower cover (103) arranged at an opening at the bottom of the shell body (101), the air inlet (108) is arranged on the upper cover (102), the blood inlet (104), the air outlet (109), the water inlet (106) and the water outlet (107) are arranged on the lower cover (103), the air outlet (110) is arranged on the shell body (101) at a position close to the upper cover (102), and the blood outlet (105) is arranged on the shell body (101) at a position close to the lower cover (103);

the oxygenation temperature changing module (200) is arranged in the shell body (101), the first blocking layer (300) is arranged between the upper end of the oxygenation temperature changing module (200) and the upper cover (102), and the second blocking layer (400) is arranged between the lower end of the oxygenator module and the lower cover (103).