CN117752297A - OCT scanning method - Google Patents

OCT scanning method Download PDF

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CN117752297A
CN117752297A CN202311813440.4A CN202311813440A CN117752297A CN 117752297 A CN117752297 A CN 117752297A CN 202311813440 A CN202311813440 A CN 202311813440A CN 117752297 A CN117752297 A CN 117752297A
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scan
scanning
oct
line
eye
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王征宇
周率
黄炳杰
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Svision Imaging Ltd
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Svision Imaging Ltd
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Abstract

The application relates to an OCT scanning method. The method comprises the following steps: controlling OCT to scan the eye to be inspected based on the target scanning line so as to obtain a B-scan image corresponding to the target scanning line; determining a scanning correction amount according to the acquired B-scan image; before the eye to be inspected is scanned based on the current scanning line, the first scanning center of the OCT is corrected according to the scanning correction amount. The method can effectively improve the accuracy of human eyeball tracking.

Description

OCT scanning method
Technical Field
The present application relates to the field of OCT technologies, and in particular, to an OCT scanning method.
Background
The optical coherence tomography (Optical Coherence Tomography, OCT) is a three-dimensional tomographic technique, and the position of an ocular lesion can be accurately determined by an OCT image obtained by scanning a human eye sphere.
In the prior art, positioning and tracking of the motion state of a human eyeball are generally realized based on a pupil camera or a fundus image so as to guide OCT to track and scan the human eyeball to obtain an OCT image.
However, there is a limit to resolution and imaging definition of an image obtained based on pupil cameras or fundus imaging, which results in poor accuracy in tracking the human eye ball.
Disclosure of Invention
Accordingly, in order to solve the above-mentioned problems, it is necessary to provide an OCT scanning method that can effectively improve the accuracy of tracking the human eye ball by OCT, and further improve the image quality of the OCT image obtained.
In a first aspect, the present application provides an OCT scanning method. The method comprises the following steps:
controlling OCT to scan the eye to be inspected based on the target scanning line so as to obtain a B-scan image corresponding to the target scanning line; determining a scanning correction amount according to the acquired B-scan image; before the eye to be inspected is scanned based on the current scanning line, the first scanning center of the OCT is corrected according to the scanning correction amount.
In one embodiment, the target scan line comprises a first scan line passing through the first scan center.
In one embodiment, the target scan line further includes a second scan line, which also passes through the first scan center and is perpendicular to the first scan line.
In one embodiment, the determining the scan correction from the acquired B-scan image includes: determining a first offset according to the acquired B-scan image, wherein the first offset is the distance between the corneal vertex and the current first scanning center in the direction of the first scanning line; the scan correction is determined based on the first offset.
In one embodiment, the determining the scan correction from the acquired B-scan image includes: respectively determining a first offset and a second offset according to the acquired B-scan image, wherein the first offset is the distance between the corneal vertex and the current first scanning center in the direction of the first scanning line, and the second offset is the distance between the corneal vertex and the current first scanning center in the direction of the second scanning line; the scan correction is determined based on the first offset and the second offset.
In one embodiment, the determining the scan correction based on the first offset and the second offset includes: determining the distance of the detected eye from the first scanning center and the included angle between the direction of the detected eye and the first scanning line according to the first offset and the second offset; and determining the scanning correction according to the distance and the included angle.
In one embodiment, the scan correction includes a first direction scan correction and a second direction scan correction, and the correcting the first scan center of the OCT according to the scan correction includes: correcting a first scanning center of the OCT in a first direction according to the first-direction scanning correction amount; and correcting the first scanning center of the OCT in the second direction according to the second direction scanning correction amount.
In one embodiment, before performing the correction processing on the first scan center of the OCT according to the scan correction amount, the method further includes: if the eye to be inspected scans the anterior ocular segment of the eye to be inspected, determining the corneal vertex of the eye to be inspected as a first scanning center of the OCT; if the eye to be inspected is scanned to scan the posterior segment of the eye to be inspected, the first scan center of the OCT is determined according to the macula and/or optic disc of the eye to be inspected, or the first scan center of the OCT is determined according to the lowest point in the RPE layer of the eye to be inspected.
In one embodiment, the method further comprises: determining a cornea location based on a layering algorithm; fitting the cornea surface based on a fitting algorithm to obtain a cornea surface fitting line; the vertex of the corneal surface fit line is determined as the corneal vertex position.
In one embodiment, the method further comprises: before the eye to be inspected is scanned based on the current scanning line, the position of the scanning galvanometer of the OCT is corrected according to the scanning correction amount.
In a second aspect, the present application also provides an OCT scanning device. The device comprises:
The acquisition module is used for controlling OCT to scan the eye to be inspected based on the target scanning line so as to acquire a B-scan image corresponding to the target scanning line;
the first determining module is used for determining a scanning correction amount according to the acquired B-scan image;
and the execution module is used for correcting the first scanning center of the OCT according to the scanning correction amount before scanning the eye to be inspected based on the current scanning line.
In one embodiment, the scanning device further includes a second determining module for determining a corneal vertex of the eye to be inspected as a first scan center of the OCT if scanning the eye to be inspected is scanning an anterior ocular segment of the eye to be inspected; if the eye to be inspected is scanned to scan the posterior segment of the eye to be inspected, the first scan center of the OCT is determined according to the macula and/or optic disc of the eye to be inspected, or the first scan center of the OCT is determined according to the lowest point in the RPE layer of the eye to be inspected.
In one embodiment, the target scan line comprises a first scan line that passes through the first scan center.
In one embodiment, the target scan line further includes a second scan line, which also passes through the first scan center and is perpendicular to the first scan line.
In one embodiment, the first determining module is specifically configured to determine a first offset according to the acquired B-scan image, where the first offset is a distance between a corneal vertex and a current first scan center in a direction of the first scan line; the scan correction is determined based on the first offset.
In one embodiment, the first determining module is specifically configured to determine a first offset and a second offset according to the acquired B-scan image, where the first offset is a distance between a corneal vertex and a current first scan center in a direction of the first scan line, and the second offset is a distance between a corneal vertex and the current first scan center in a direction of the second scan line; the scan correction is determined based on the first offset and the second offset.
In one embodiment, the first determining module is specifically configured to determine, according to the first offset and the second offset, a distance of the eye to be inspected from the first scanning center and an included angle between a direction in which the eye to be inspected is located and the first scanning line; and determining the scanning correction according to the distance and the included angle.
In one embodiment, the execution module is specifically configured to perform a correction process on the first scan center of the OCT in a first direction according to the first direction scan correction amount; and correcting the first scanning center of the OCT in the second direction according to the second direction scanning correction amount.
In one embodiment, the first determination module is specifically configured to determine the cornea location based on a layering algorithm; fitting the cornea surface based on a fitting algorithm to obtain a cornea surface fitting line; the vertex of the corneal surface fit line is determined as the corneal vertex position.
In one embodiment, the execution module is specifically configured to perform correction processing on the position of the scanning galvanometer of the OCT according to the scanning correction amount before scanning the eye to be inspected based on the current scanning line.
In a third aspect, the present application also provides a computer device. The computer device comprises a memory storing a computer program and a processor implementing the steps of any of the above first aspects when the computer program is executed.
In a fourth aspect, the present application also provides a computer-readable storage medium. A computer readable storage medium having stored thereon a computer program which when executed by a processor performs the steps of any of the first aspects described above.
In a fifth aspect, the present application also provides a computer program product. The computer program product comprising a computer program which, when executed by a processor, implements the steps of any of the first aspects described above.
According to the OCT scanning method, firstly, the OCT is controlled to scan the eye to be inspected based on the target scanning line so as to obtain the B-scan image corresponding to the target scanning line, then the scanning correction amount is determined according to the obtained B-scan image, and before the eye to be inspected is scanned based on the current scanning line, the first scanning center of the OCT is corrected according to the scanning correction amount. According to the OCT scanning method, the scanning correction amount is determined based on the B-scan image corresponding to the target scanning line, and then the scanning center of the OCT is corrected based on the scanning correction amount, so that tracking scanning of the human eye ball is achieved.
Drawings
FIG. 1 is a flow chart of an OCT scanning method in one embodiment;
FIG. 2 is a flow chart of a method for determining a scan correction based on the acquired B-scan image in one embodiment;
FIG. 3 is a flowchart of a method for determining a scan correction according to the acquired B-scan image according to another embodiment;
FIG. 4 is a flow chart of a method for determining the scan correction according to the first offset and the second offset in one embodiment;
FIG. 5 is a flowchart of a method for correcting a first scan center of OCT according to the scan correction amount in one embodiment;
FIG. 6 is a flow chart of a method of determining corneal vertex position in the B-scan image in one embodiment;
FIG. 7 is a flow chart of a method for scanning a target scan line including only a first scan line in one embodiment;
FIG. 8 is a flow chart of a scanning method in which a target scan line includes a first scan line and a second scan line in one embodiment;
FIG. 9 is a block diagram showing the structure of an OCT scanning device in one embodiment;
FIG. 10 is a block diagram showing the structure of an OCT scanner in another embodiment;
FIG. 11 is an internal block diagram of a computer device in one embodiment;
FIG. 12 is a schematic diagram of a scanning mode in one embodiment;
FIG. 13 is a schematic diagram of determining a scan correction in one embodiment;
FIG. 14 is a schematic diagram of a B-scan image in one embodiment;
fig. 15 is a schematic diagram of determining a scan correction amount in another embodiment.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application will be further described in detail with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the present application.
Optical coherence tomography (Optical Coherence Tomography, OCT) is a three-dimensional tomographic technique that allows accurate determination of the location of a keratopathy by scanning the sphere of the eye with an OCT image of the anterior segment.
In the prior art, positioning and tracking of the motion state of the human eyeball are generally realized based on a pupil camera so as to guide the OCT to track and scan the human eyeball, so as to obtain an OCT image of the anterior segment of the eye.
However, there is a limit to pupil camera resolution and imaging definition, so that the accuracy of tracking the human eye ball based on the pupil camera guiding OCT is poor.
In view of this, the present application provides an OCT scanning method, which can effectively improve the accuracy of tracking the human eye ball by OCT.
The execution subject of the OCT scanning method provided in the embodiments of the present application may be a computer device, which may be a server.
In one embodiment, as shown in fig. 1, an OCT scanning method is provided, the method comprising the steps of:
step 101, controlling OCT to scan the eye to be inspected based on the target scanning line so as to obtain a B-scan image corresponding to the target scanning line.
The B-scan image, i.e., a two-dimensional cross-sectional image, is generated by the OCT beam being scanned laterally across the eye being examined.
In one possible implementation, the operator may determine the target scan line according to the actual requirement, and then control the OCT to scan the eye to be inspected based on the target scan line, so as to obtain the B-scan image corresponding to the target scan line.
In another possible implementation manner, the scanning manner of the OCT may be determined first, a target scan line may be determined based on the scanning manner, and then the OCT may be controlled to scan the eye to be inspected based on the target scan line, so as to obtain a B-scan image corresponding to the target scan line.
And 102, determining a scanning correction amount according to the acquired B-scan image.
In one possible implementation manner, the OCT may be controlled to scan the eye to be inspected according to the scanning manner shown in fig. 12, where the number in fig. 12 is used to characterize the scanning sequence, for example, the OCT may determine, in the eye to be inspected, a target position that corresponds to the scanning center in fig. 12 when scanning the eye to be inspected, the intersection point of each scanning line in fig. 12 is the scanning center, in the first scanning, the OCT is controlled to scan the eye to be inspected according to the scanning line number 1, the scanning line number 1 is the target scanning line, in the second scanning, the OCT is controlled to scan the eye to be inspected according to the scanning line number 2, in the actual scanning, since the eye to be inspected is in a moving state, in the second scanning, the scanning center may not be in the target position, therefore, the offset may be determined according to the B-scan image obtained in the second scanning, the offset refers to the scanning center and the target position, and the offset may be determined according to the offset of the scanning center and the offset of the target position, and the correction of the offset may be used to the correction of the scanning center.
Step 103, before scanning the eye to be inspected based on the current scanning line, correcting the first scanning center of the OCT according to the scanning correction amount.
Optionally, the first scanning center is also referred to above.
In one possible implementation, as described above, the first scan center may not be at the target position during the second scan, so the scan correction amount may be determined according to the B-scan image obtained during the second scan, and the first scan center of the OCT may be corrected according to the scan correction amount, and after the correction, the OCT is controlled to scan the eye to be inspected according to the scan line numbered 3.
In another possible implementation, as described above, the first scan center may not be at the target position during the second scan, so the scan correction amount may be determined according to the B-scan image obtained during the second scan, and during the determining of the scan correction amount, the OCT may continuously perform the scan process, that is, the OCT continues to perform the scan process according to the scan sequence, and if during the performing of the scan process by the OCT according to the scan line numbered 5, the scan correction amount is determined, the first scan center of the OCT is corrected according to the scan correction amount before the performing of the scan process by the OCT according to the scan line numbered 6, and then the OCT is controlled to perform the scan process according to the scan line numbered 6.
According to the scanning method, the OCT is controlled to scan the eye to be inspected based on the target scanning line, so that a B-scan image corresponding to the target scanning line is obtained, and the scanning correction amount is determined according to the obtained B-scan image; before the eye to be inspected is scanned based on the current scanning line, the first scanning center of the OCT is corrected according to the scanning correction amount. According to the scanning method, the scanning correction amount is determined based on the B-scan image corresponding to the target scanning line, and then the scanning center of the OCT is corrected based on the scanning correction amount, so that tracking scanning of the human eye ball is achieved.
In an alternative embodiment of the present application, before performing the correction processing on the first scan center of the OCT according to the scan correction amount, the method further includes: if the eye to be inspected scans the anterior ocular segment of the eye to be inspected, determining the corneal vertex of the eye to be inspected as a first scanning center of the OCT; if the eye to be inspected is scanned to scan the posterior segment of the eye to be inspected, the first scan center of the OCT is determined according to the macula and/or optic disc of the eye to be inspected, or the first scan center of the OCT is determined according to the lowest point in the RPE layer of the eye to be inspected.
In one possible implementation, if the OCT is controlled to scan the anterior segment of the eye to be inspected based on the target scan line, the corneal vertex of the eye to be inspected may be determined as the first scan center of the OCT, and the anterior segment of the eye to be inspected includes at least the pupil, the cornea, and the iris structure.
In the embodiment of the present application, the anterior ocular segment of the eye to be inspected is scanned, and the vertex of the cornea of the eye to be inspected is determined as the first scanning center of the OCT.
In another possible implementation manner, if the posterior segment of the eye to be inspected includes at least a retinal structure, a point on the macular area or the optic disc area of the eye to be inspected may be determined as the first scanning center of the OCT, preferably, the macular center may be selected as the first scanning center or the optic disc center may be selected as the first scanning center, or the first scanning center of the OCT may be determined according to the macular area and the optic disc area of the eye to be inspected, preferably, a point on a line where the macular center and the optic disc center are located may be determined as the first scanning center.
In another possible implementation manner, if the OCT is controlled to scan the posterior segment of the eye to be inspected based on a plurality of scan lines in the scan line group, a B-scan image of the eye to be inspected may be acquired first, and then signal intensity maps of a plurality of a-scan images corresponding to the B-scan image may be acquired; a target a-scan image is determined from a plurality of a-scan images based on the plurality of signal intensity maps, the target a-scan image being an a-scan image having a greatest depth position of a minimum signal intensity of the plurality of a-scan images, and a position of the target a-scan image in the B-scan image is determined to be a lowest point position in a retinal pigment epithelium (retinal pigment epithelium, RPE) layer in the first B-scan image, and a lowest point position in the RPE layer is determined to be the first scan center.
In another possible implementation manner, the RPE layer position may be determined based on a layering algorithm, and then the fitting process is performed on the RPE layer based on a fitting algorithm, so as to obtain an RPE layer fitting line, a low point of the RPE layer fitting line is determined as a lowest point in the RPE layer, and the lowest point in the RPE layer is determined as the first scan center.
It should be noted that, if the lowest point in the RPE layer of the eye to be inspected is determined as the first scan center of the OCT, the correction amount determining method for determining the first scan center in the scan process is the same as the correction amount determining method when the corneal vertex is determined as the first scan center, and the process of correcting the first scan center according to the correction amount is also the same, which will not be described in detail later.
In one embodiment, the target scan line comprises a first scan line passing through the first scan center.
In one possible implementation, as shown in fig. 12, if the target scan line includes only the first scan line, it may be understood that, every time a scan process is performed, a B-scan image corresponding to the target scan line is acquired, a scan correction amount is determined according to the acquired B-scan image, and finally, correction processing is performed on the first scan center of the OCT according to the scan correction amount, for example, when the OCT is controlled to perform the scan process according to the scan line with the number of 1, the scan line with the number of 1 is determined as the target scan line, after the OCT is controlled to perform the scan process according to the target scan line, a B-scan image corresponding to the target scan line is acquired to determine the scan correction amount, correction processing is performed on the first scan center of the OCT according to the scan correction amount, when the OCT is controlled to perform the scan process according to the scan line with the number of 2, and after the OCT is controlled to perform the scan process according to the target scan line, the B-scan image corresponding to the scan image is determined to the scan correction amount.
In one embodiment, as shown in FIG. 2, the determining the scan correction from the acquired B-scan image includes the steps of:
step 201, determining a first offset according to the acquired B-scan image.
Optionally, the first offset is a distance between a corneal vertex and a current first scan center in a direction of the first scan line.
In one possible implementation, the cornea position may be determined based on a layering algorithm and the B-scan image, and then a cornea surface fitting line may be determined based on a fitting algorithm, where a vertex of the cornea surface fitting line is the cornea vertex position, and the first offset may be determined based on the membrane vertex position and the current first scan center, and a distance between the cornea vertex position and the current first scan center is the first offset.
Step 202, determining the scan correction according to the first offset.
Alternatively, the scan correction may include an x-axis correction and a y-axis correction.
In one possible implementation, as shown in FIG. 13, assume that the first offset is I 0 The first scan line and x-axis have an angle alpha, and the x-axis correction is I 0 cos alpha, the y-axis correction is I 0 sinα。
In an alternative embodiment of the present application, after determining the scan correction, the first scan center of the OCT is further corrected according to the scan correction.
In one possible implementation manner, the position of the first scanning center may include an x-axis coordinate position and a y-axis coordinate position, the x-axis coordinate position is corrected according to the x-axis correction amount to obtain a corrected target x-axis coordinate position, specifically, the x-axis correction amount may be overlapped with the x-axis coordinate position to obtain a target x-axis coordinate position, the y-axis coordinate position is corrected according to the y-axis correction amount to obtain a corrected target y-axis coordinate position, and specifically, the y-axis correction amount may be overlapped with the y-axis coordinate position to obtain a target y-axis coordinate position.
In an alternative embodiment of the present application, the method further comprises: before the eye to be inspected is scanned based on the current scanning line, the position of the scanning galvanometer of the OCT is corrected according to the scanning correction amount.
In one possible implementation, the scanning position is controlled by the OCT control system (optionally, a central controller) by controlling the positions of the scanning galvanometer for scanning in the x direction and the scanning galvanometer for scanning in the y direction, so that correction processing is further required for the position of the scanning galvanometer of the OCT, specifically, the x-axis scanning correction amount and the y-axis correction amount are respectively superimposed on the preset scanning positions of the corresponding galvanometer, and the scanning galvanometer is controlled based on the obtained actual scanning positions.
In one embodiment, the target scan line further includes a second scan line, which also passes through the first scan center and is perpendicular to the first scan line.
In one possible implementation manner, as shown in fig. 12, if the target scan line includes a first scan line and a second scan line, it may be understood that each time a scan process is performed twice, a B-scan image corresponding to the target scan line is obtained, a scan correction amount is determined according to the obtained B-scan image, and finally, correction processing is performed on a first scan center of the OCT according to the scan correction amount, for example, the OCT is controlled to perform a scan process according to scan line number 1, the OCT is controlled to perform a scan process according to scan line number 2, the scan line number 1 and the scan line number 2 are determined to be a first scan line and a second scan line, after the OCT is controlled to perform a scan process according to the second scan line, a B-scan image corresponding to the first scan line and the second scan line is obtained to determine a scan correction amount according to the scan correction amount, and the OCT is controlled to perform a scan process according to scan line number 3, and the OCT is controlled to perform a scan process according to scan line number 4 after the OCT is controlled to perform a scan process corresponding to the first scan line number 4 and the scan line number 4 is determined to be a scan process according to the first scan line number 4.
In one embodiment, as shown in FIG. 3, the determining the scan correction from the acquired B-scan image includes the steps of:
step 301, determining a first offset and a second offset according to the acquired B-scan image.
Optionally, the first offset is a distance between a corneal vertex and the current first scanning center in a direction of the first scanning line,
in one possible implementation, the corneal vertex position may be determined in the B-scan image corresponding to the first scan line, where the distance between the corneal vertex position and the current first scan center is the first offset.
Optionally, the second offset is a distance between a corneal vertex and the current first scan center in a direction of the second scan line.
In one possible implementation, the corneal vertex position may be determined in the B-scan image corresponding to the second scan line, where the distance between the corneal vertex position and the current first scan center is the second offset.
Step 302, determining the scan correction according to the first offset and the second offset.
In one possible implementation, the scan correction may be determined based on an algorithmic process, the first offset and the second offset.
In one embodiment, as shown in fig. 4, the determining the scan correction according to the first offset and the second offset includes the steps of:
step 401, determining a distance of the inspected eye from the first scanning center and an included angle between the direction of the inspected eye and the first scanning line according to the first offset and the second offset.
In one possible implementation, as shown in fig. 15, X 'is a first scan line, Y' is a second scan line, and the first offset is I 0 The second offset is I 1 The included angle between the first scanning line and the x-axis is alpha, the included angle between the direction of the inspected eye and the first scanning line is theta, the distance of the inspected eye deviating from the first scanning center is R, then I 0 =R×cos(theta),I 1 =r×sin (theta), available simultaneously,R=sqrt(I 0 ×I 0 +I 1 ×I 1 )。
step 402, determining the scan correction according to the distance and the included angle.
Optionally, the scan correction includes a first direction scan correction and a second direction scan correction.
In one possible implementation, the first directional scan correction is an x-axis scan correction, which is rxcos (alpha+theta), and the second directional scan correction is a y-axis scan correction, which is rxsin (alpha+theta).
In one embodiment, as shown in fig. 5, the correction processing is performed on the first scan center of the OCT according to the scan correction amount, including the following steps:
step 501, performing correction processing on the first scan center of the OCT in the first direction according to the first direction scan correction amount.
Step 502, performing correction processing on the first scan center of the OCT in the second direction according to the second direction scan correction amount.
In one possible implementation manner, the correction is performed on the scan center of the OCT in the x direction according to the x-axis scan correction amount, the correction is performed on the scan center of the OCT in the y direction according to the y-axis scan correction amount, specifically, the position of the first scan center may include an x-axis coordinate position and a y-axis coordinate position, the correction is performed on the x-axis coordinate position according to the x-axis correction amount, so as to obtain a corrected target x-axis coordinate position, that is, the x-axis correction amount and the x-axis coordinate position are superimposed, so as to obtain a target x-axis coordinate position, and the correction is performed on the y-axis coordinate position according to the y-axis correction amount, so as to obtain a corrected target y-axis coordinate position, that is, the y-axis correction amount and the y-axis coordinate position are superimposed, so as to obtain the target y-axis coordinate position.
In an alternative embodiment of the present application, the method further comprises: before the eye to be inspected is scanned based on the current scanning line, the position of the scanning galvanometer of the OCT is corrected according to the scanning correction amount.
In one possible implementation, the scanning position is controlled by the OCT control system (optionally, a central controller) by controlling the positions of the scanning galvanometer for scanning in the x direction and the scanning galvanometer for scanning in the y direction, so that correction processing is further required for the position of the scanning galvanometer of the OCT, specifically, the x-axis scanning correction amount and the y-axis correction amount are respectively superimposed on the preset scanning positions of the corresponding galvanometer, and the scanning galvanometer is controlled based on the obtained actual scanning positions.
In one embodiment, as shown in FIG. 6, determining the corneal vertex position in the B-scan image includes the steps of:
step 601, determining a cornea location based on a layering algorithm.
In one possible implementation, the anterior surface position of the cornea or the posterior surface position of the cornea may be determined based on a hierarchical algorithm of deep learning.
In another possible implementation, the anterior surface position of the cornea or the posterior surface position of the cornea may also be determined based on a shortest path layering algorithm.
Step 602, fitting the cornea surface based on a fitting algorithm to obtain a cornea surface fitting line.
In one possible implementation, the anterior surface of the cornea may be fitted based on a fitting algorithm to obtain a fitting line of the anterior surface of the cornea, as shown in fig. 14, and the line A1 in fig. 14 is the fitting line of the anterior surface of the cornea.
In another possible implementation, the posterior surface of the cornea may be fitted based on a fitting algorithm to obtain a posterior surface of the cornea fitting line.
Step 603, determining the vertex of the cornea surface fitting line as the cornea vertex position.
In one possible implementation, the anterior corneal surface fit line is parabolic, and the vertex of the fit line may be determined as the corneal vertex position.
In another possible implementation, the posterior corneal surface fit line is parabolic, and the vertex of the fit line may be determined as the corneal vertex position.
In one embodiment, as shown in fig. 7, another OCT scanning method is provided, whose target scan line includes only the first scan line, the method comprising the steps of:
in step 701, the OCT is controlled to scan the eye to be inspected based on a target scan line, so as to obtain a B-scan image corresponding to the target scan line, where the target scan line includes a first scan line, and the first scan line passes through the first scan center.
Step 702, determining a first offset according to the B-scan image.
Step 703, determining the scan correction according to the first offset.
Step 704, before scanning the eye to be inspected based on the current scanning line, the first scanning center of the OCT and the scanning galvanometer are corrected according to the scanning correction amount.
In one embodiment, as shown in fig. 8, another OCT scanning method is provided, whose target scan line includes a first scan line and a second scan line, the method comprising the steps of:
step 801, controlling OCT to scan an eye to be inspected based on a target scan line, so as to obtain a B-scan image corresponding to the target scan line, where the target scan line includes a first scan line and a second scan line, the first scan line passes through the first scan center, and the second scan line also passes through the first scan center and is perpendicular to the first scan line.
Step 802, determining a first offset and a second offset according to the B-scan image, wherein the first offset is a distance between a corneal vertex and a current first scan center in a direction of the first scan line, and the second offset is a distance between a corneal vertex and the current first scan center in a direction of the second scan line.
Step 803, determining a distance of the inspected eye from the first scanning center and an included angle between a direction of the inspected eye and the first scanning line according to the first offset and the second offset; and determining the scanning correction according to the distance and the included angle.
Step 804, before scanning the eye to be inspected based on the current scanning line, correcting the first scanning center of the OCT in a first direction according to the first direction scanning correction amount; and correcting the first scanning center of the OCT in the second direction according to the second direction scanning correction amount, and correcting the scanning galvanometer of the OCT according to the scanning correction amount.
It should be understood that, although the steps in the flowcharts related to the embodiments described above are sequentially shown as indicated by arrows, these steps are not necessarily sequentially performed in the order indicated by the arrows. The steps are not strictly limited to the order of execution unless explicitly recited herein, and the steps may be executed in other orders. Moreover, at least some of the steps in the flowcharts described in the above embodiments may include a plurality of steps or a plurality of stages, which are not necessarily performed at the same time, but may be performed at different times, and the order of the steps or stages is not necessarily performed sequentially, but may be performed alternately or alternately with at least some of the other steps or stages.
Based on the same inventive concept, the embodiment of the application also provides a scanning device for realizing the above-mentioned related scanning method. The implementation of the solution provided by the device is similar to that described in the above method, so the specific limitations of one or more embodiments of the scanning device provided below can be referred to above for limitations of the OCT scanning method, and will not be repeated here.
In one embodiment, as shown in fig. 9, there is provided an OCT scanning device 100 including: an acquisition module 1001, a first determination module 1002, and an execution module 1003, wherein:
the acquisition module is used for controlling OCT to scan the eye to be inspected based on the target scanning line so as to acquire a B-scan image corresponding to the target scanning line;
the first determining module is used for determining a scanning correction amount according to the acquired B-scan image;
and the execution module is used for correcting the first scanning center of the OCT according to the scanning correction amount before scanning the eye to be inspected based on the current scanning line.
In one embodiment, as shown in fig. 10, another OCT scanning device 110 is provided, and the OCT scanning device 110 includes a second determination module 1004 in addition to the respective modules included in the OCT scanning device 100.
In one embodiment, the second determining module 1004 is configured to determine a corneal vertex of the eye to be inspected as a first scan center of the OCT if scanning the eye to be inspected is scanning an anterior ocular segment of the eye to be inspected; if the eye to be inspected is scanned to scan the posterior segment of the eye to be inspected, the first scan center of the OCT is determined according to the macula and/or optic disc of the eye to be inspected, or the first scan center of the OCT is determined according to the lowest point in the RPE layer of the eye to be inspected.
In one embodiment, the target scan line comprises a first scan line that passes through the first scan center.
In one embodiment, the target scan line further includes a second scan line, which also passes through the first scan center and is perpendicular to the first scan line.
In one embodiment, the first determining module 1002 is specifically configured to determine a first offset according to the acquired B-scan image, where the first offset is a distance between a corneal vertex and the current first scan center in the direction of the first scan line; the scan correction is determined based on the first offset.
In one embodiment, the first determining module 1002 is specifically configured to determine a first offset and a second offset according to the acquired B-scan image, where the first offset is a distance between a corneal vertex and a current first scan center in a direction of the first scan line, and the second offset is a distance between a corneal vertex and the current first scan center in a direction of the second scan line; the scan correction is determined based on the first offset and the second offset.
In one embodiment, the first determining module 1002 is specifically configured to determine, according to the first offset and the second offset, a distance of the inspected eye from the first scan center and an included angle between a direction in which the inspected eye is located and the first scan line; and determining the scanning correction according to the distance and the included angle.
In one embodiment, the execution module 1003 is specifically configured to perform a correction process on the first scan center of the OCT in the first direction according to the first direction scan correction amount; and correcting the first scanning center of the OCT in the second direction according to the second direction scanning correction amount.
In one embodiment, the first determining module 1002 is specifically configured to determine a cornea location based on a layering algorithm; fitting the cornea surface based on a fitting algorithm to obtain a cornea surface fitting line; the vertex of the corneal surface fit line is determined as the corneal vertex position.
In one embodiment, the execution module 1003 is specifically configured to correct the position of the scanning galvanometer of the OCT according to the scanning correction amount before scanning the eye to be inspected based on the current scanning line.
The various modules in the scanning device described above may be implemented in whole or in part by software, hardware, and combinations thereof. The above modules may be embedded in hardware or may be independent of a processor in the computer device, or may be stored in software in a memory in the computer device, so that the processor may call and execute operations corresponding to the above modules.
In one embodiment, a computer device is provided, which may be a server, and the internal structure of which may be as shown in fig. 11. The computer device includes a processor, a memory, an Input/Output interface (I/O) and a communication interface. The processor, the memory and the input/output interface are connected through a system bus, and the communication interface is connected to the system bus through the input/output interface. Wherein the processor of the computer device is configured to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system, computer programs, and a database. The internal memory provides an environment for the operation of the operating system and computer programs in the non-volatile storage media. The database of the computer device is for storing data. The input/output interface of the computer device is used to exchange information between the processor and the external device. The communication interface of the computer device is used for communicating with an external terminal through a network connection. The computer program is executed by a processor to implement an OCT scanning method.
It will be appreciated by those skilled in the art that the structure shown in fig. 11 is merely a block diagram of a portion of the structure associated with the present application and is not limiting of the computer device to which the present application applies, and that a particular computer device may include more or fewer components than shown, or may combine some of the components, or have a different arrangement of components.
In an embodiment, a computer device is provided comprising a memory and a processor, the memory having stored therein a computer program, the processor implementing the steps of any of the above embodiments when the computer program is executed.
In one embodiment, a computer readable storage medium is provided, having a computer program stored thereon, which when executed by a processor, implements the steps of any of the above embodiments.
In an embodiment, a computer program product is provided comprising a computer program which, when executed by a processor, implements the steps of any of the above embodiments.
It should be noted that, the user information (including, but not limited to, user equipment information, user personal information, etc.) and the data (including, but not limited to, data for analysis, stored data, presented data, etc.) referred to in the present application are information and data authorized by the user or sufficiently authorized by each party, and the collection, use and processing of the related data are required to comply with the related laws and regulations and standards of the related countries and regions.
Those skilled in the art will appreciate that implementing all or part of the above described methods may be accomplished by way of a computer program stored on a non-transitory computer readable storage medium, which when executed, may comprise the steps of the embodiments of the methods described above. Any reference to memory, database, or other medium used in the various embodiments provided herein may include at least one of non-volatile and volatile memory. The nonvolatile Memory may include Read-Only Memory (ROM), magnetic tape, floppy disk, flash Memory, optical Memory, high density embedded nonvolatile Memory, resistive random access Memory (ReRAM), magnetic random access Memory (Magnetoresistive Random Access Memory, MRAM), ferroelectric Memory (Ferroelectric Random Access Memory, FRAM), phase change Memory (Phase Change Memory, PCM), graphene Memory, and the like. Volatile memory can include random access memory (Random Access Memory, RAM) or external cache memory, and the like. By way of illustration, and not limitation, RAM can be in the form of a variety of forms, such as static random access memory (Static Random Access Memory, SRAM) or dynamic random access memory (Dynamic Random Access Memory, DRAM), and the like. The databases referred to in the various embodiments provided herein may include at least one of relational databases and non-relational databases. The non-relational database may include, but is not limited to, a blockchain-based distributed database, and the like. The processors referred to in the embodiments provided herein may be general purpose processors, central processing units, graphics processors, digital signal processors, programmable logic units, quantum computing-based data processing logic units, etc., without being limited thereto.
The technical features of the above embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The above examples only represent a few embodiments of the present application, which are described in more detail and are not to be construed as limiting the scope of the present application. It should be noted that it would be apparent to those skilled in the art that various modifications and improvements could be made without departing from the spirit of the present application, which would be within the scope of the present application. Accordingly, the scope of protection of the present application shall be subject to the appended claims.

Claims (10)

1. An OCT scanning method, the method comprising:
controlling OCT to scan an eye to be inspected based on a target scanning line so as to obtain a B-scan image corresponding to the target scanning line;
determining a scanning correction amount according to the acquired B-scan image;
before the eye to be inspected is scanned based on the current scanning line, the first scanning center of the OCT is corrected according to the scanning correction amount.
2. The method of claim 1, wherein the target scan line comprises a first scan line, the first scan line passing through the first scan center.
3. The method of claim 2, wherein the target scan line further comprises a second scan line, the second scan line also passing through the first scan center and being perpendicular to the first scan line.
4. The method of claim 2, wherein the determining a scan correction from the acquired B-scan image comprises:
determining a first offset according to the acquired B-scan image, wherein the first offset is the distance between the corneal vertex and the current first scanning center in the direction of the first scanning line;
and determining the scanning correction according to the first offset.
5. A method according to claim 3, wherein said determining a scan correction from said acquired B-scan image comprises:
respectively determining a first offset and a second offset according to the acquired B-scan image, wherein the first offset is the distance between the corneal vertex and the current first scanning center in the direction of the first scanning line, and the second offset is the distance between the corneal vertex and the current first scanning center in the direction of the second scanning line;
And determining the scanning correction according to the first offset and the second offset.
6. The method of claim 5, wherein the determining the scan correction from the first offset and the second offset comprises:
determining the distance of the detected eye from the first scanning center and the included angle between the direction of the detected eye and the first scanning line according to the first offset and the second offset;
and determining the scanning correction according to the distance and the included angle.
7. The method of claim 6, wherein the scan correction comprises a first direction scan correction and a second direction scan correction, the correcting the first scan center of the OCT according to the scan correction comprising:
performing correction processing on a first scanning center of the OCT in a first direction according to the first direction scanning correction amount;
and correcting the first scanning center of the OCT in the second direction according to the second direction scanning correction amount.
8. The method of any one of claims 1 to 7, wherein prior to correcting the first scan center of the OCT according to the scan correction, the method further comprises:
If the eye to be inspected is scanned to scan the anterior ocular segment of the eye to be inspected, determining the corneal vertex of the eye to be inspected as a first scanning center of the OCT;
if the eye to be inspected is scanned to scan the posterior segment of the eye to be inspected, the first scanning center of the OCT is determined according to the macula and/or optic disc of the eye to be inspected, or the first scanning center of the OCT is determined according to the lowest point in the RPE layer of the eye to be inspected.
9. The method of claim 8, wherein the method further comprises:
determining a cornea location based on a layering algorithm;
fitting the cornea surface based on a fitting algorithm to obtain a cornea surface fitting line;
and determining the vertex of the cornea surface fitting line as the cornea vertex position.
10. The method according to any one of claims 1 to 7, further comprising:
before the eye to be inspected is scanned based on the current scanning line, the position of the OCT scanning galvanometer is corrected according to the scanning correction amount.
CN202311813440.4A 2023-12-26 2023-12-26 OCT scanning method Pending CN117752297A (en)

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