CN117705560A - Real-time abrasion test device for cardiovascular implant - Google Patents
Real-time abrasion test device for cardiovascular implant Download PDFInfo
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- CN117705560A CN117705560A CN202410167192.9A CN202410167192A CN117705560A CN 117705560 A CN117705560 A CN 117705560A CN 202410167192 A CN202410167192 A CN 202410167192A CN 117705560 A CN117705560 A CN 117705560A
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- 238000012360 testing method Methods 0.000 title claims abstract description 209
- 230000002526 effect on cardiovascular system Effects 0.000 title claims abstract description 32
- 239000007943 implant Substances 0.000 title claims abstract description 32
- 238000005299 abrasion Methods 0.000 title claims abstract description 27
- 230000001105 regulatory effect Effects 0.000 claims abstract description 22
- 239000012530 fluid Substances 0.000 claims abstract description 14
- 230000001502 supplementing effect Effects 0.000 claims abstract description 11
- 239000007788 liquid Substances 0.000 claims description 100
- 230000004087 circulation Effects 0.000 claims description 13
- 238000004891 communication Methods 0.000 claims description 12
- 238000013016 damping Methods 0.000 claims description 12
- 238000010438 heat treatment Methods 0.000 claims description 9
- 230000005540 biological transmission Effects 0.000 claims description 7
- 230000003139 buffering effect Effects 0.000 claims description 3
- 238000001802 infusion Methods 0.000 claims description 3
- 210000003709 heart valve Anatomy 0.000 abstract description 16
- 230000010349 pulsation Effects 0.000 abstract description 5
- 230000017531 blood circulation Effects 0.000 abstract description 3
- 230000000712 assembly Effects 0.000 abstract 2
- 238000000429 assembly Methods 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 19
- 230000033001 locomotion Effects 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 239000000463 material Substances 0.000 description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 4
- 230000008859 change Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000004962 physiological condition Effects 0.000 description 3
- 208000018578 heart valve disease Diseases 0.000 description 2
- -1 acryl Chemical group 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002637 fluid replacement therapy Methods 0.000 description 1
- 230000001121 heart beat frequency Effects 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
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Abstract
The invention belongs to the technical field of cardiovascular implant wear tests, and particularly relates to a cardiovascular implant real-time wear test device which comprises a test module, a driving assembly, a fluid supplementing module and a camera module, wherein the test module comprises a main board, test assemblies which respectively correspond to all independent inner cavities in the main board to form independent test channels, and the driving assembly which is correspondingly connected with the test channels, and the test assemblies comprise an adjusting box body, and a test pipe and a return pipe which are connected between the adjusting box body and the corresponding independent inner cavities; a one-way valve I is arranged in the independent inner cavity, and a one-way valve II is arranged in the regulating box body; the fluid supplementing module is used for supplementing test fluid into the test channel; the camera module records the test condition of the adjusting box body in the test channel. The invention can simulate the environment with the height close to the normal pulsation of the heart of the human body and the blood flow, ensure the reliability of the abrasion test result and provide reliable basis for evaluating the service life of the artificial heart valve.
Description
Technical Field
The invention belongs to the technical field of cardiovascular implant wear tests, and particularly relates to a real-time wear test device for a cardiovascular implant.
Background
Heart valve disease is a common heart disease, and currently, a prosthetic heart valve is adopted for replacement, so that the prosthetic heart valve is used for replacing a diseased valve to work, and the heart valve disease is an effective treatment scheme. Before the artificial heart valve is put into use, the service life of the artificial heart valve needs to be evaluated, and in-vitro testing of a wear testing machine is an important evaluation means.
When the artificial heart valve is subjected to abrasion test, the artificial heart valve needs to be subjected to real-time test under an environment extremely similar to the physiological condition of a human body so as to test the dynamic condition of the artificial heart valve which is opened and closed for a long time, and therefore, the simulation of the physiological condition of the human body such as a physiological pressure curve, the pulse frequency of the human body and the like in test equipment is important.
The existing wear test equipment can only provide simulated liquid pulsation circulation, but cannot provide test conditions similar to the physiological environment of a human body, such as how to enable the artificial heart valve to normally open and close under the similar human body pulsation frequency, and the pressure curves before and after the opening and closing accord with corresponding physiological curves. The reliability of test results obtained by the test equipment is poor, and the service life of the artificial heart valve cannot be accurately estimated.
Disclosure of Invention
The invention aims to provide a real-time abrasion test device for cardiovascular implants, which aims to solve the problem of poor reliability of abrasion test results.
The real-time abrasion test device for the cardiovascular implant is realized by the following steps:
a real-time abrasion test device for cardiovascular implant, comprising
The test module comprises a main board, test components which respectively correspond to all independent inner cavities in the main board to form independent test channels, and a driving component which is correspondingly connected with the test channels, wherein the test components comprise an adjusting box body, and a test pipe and a return pipe which are connected between the adjusting box body and the corresponding independent inner cavities;
the independent inner cavity is internally provided with a one-way valve I, the regulating box body is internally provided with a one-way valve II, and test liquid in the test channel flows out of the independent inner cavity and flows through the test tube, the regulating box body and the return tube in sequence and then flows back into the corresponding independent inner cavity;
the cardiovascular implant is placed within the test tube;
the fluid supplementing module is connected with the test channel and is used for supplementing test fluid into the test channel;
the camera module can be arranged opposite to any adjusting box body so as to record the test condition of the adjusting box body in a test channel.
Further, the independent inner cavity comprises a communication cavity opposite to the test tube and the driving assembly and a backflow cavity positioned above the communication cavity, and the one-way valve I is installed in the backflow cavity by using a one-way valve sleeve.
Further, the inside of adjusting the box include with the experimental pipe is relative observes the chamber, and is located observe the circulation chamber in chamber top, check valve II installs circulation chamber with observe the intercommunication department in chamber.
Further, the top of the adjusting box body is provided with a transparent liquid buffer box communicated with the inside of the adjusting box body.
Further, an energy buffer cavity is formed in the bottom of the adjusting box body, an elastic diaphragm is arranged between the energy buffer cavity and the adjusting box body, and a spring is arranged below the elastic diaphragm;
the damping adjusting valve is installed at the bottom of the energy buffer cavity, a through hole I is formed in the damping adjusting valve, a through hole II is formed in a spring base at the bottom of the spring, and the damping adjusting valve can adjust the communication quantity of the through hole I and the through hole II through rotation.
Further, a throttle cavity opposite to the return pipe is arranged in the adjusting box body, and a throttle valve positioned on one side of the adjusting box body is arranged in the throttle cavity.
Further, the driving component comprises a driving element and a transmission component arranged between the driving element and the main board;
the transmission assembly comprises a sliding sleeve and a pushing piece which is arranged in the sliding sleeve and connected with the power output end of the driving element, and the pushing piece can reciprocate in the sliding sleeve.
Further, a heating plate is arranged on one side of the main plate, which faces the driving assembly;
the test tube is of a two-section structure, the cardiovascular implant is placed in a corresponding clamp, and the clamp is fixed at the joint of the two sections of the test tube;
the reflux pipe is of a telescopic sleeve structure with two or more sections which can be disassembled.
Further, the fluid infusion module comprises a box base and a liquid storage tank arranged above the box base, and the liquid storage tank is connected with each test channel through a pipeline.
Further, the camera module comprises a movable camera support and a high-speed video camera mounted on the camera support, wherein a lens end of the high-speed video camera is provided with an aperture fixed on the camera support.
After the technical scheme is adopted, the invention has the following beneficial effects:
according to the invention, through the arrangement of the two one-way valves, test liquid in each test channel can be subjected to one-way circulation, so that the environment which is close to normal pulsation of a human heart and blood flow can be simulated, the reliability of abrasion test results is ensured, and a reliable basis is provided for evaluating the service life of the artificial heart valve.
Drawings
The invention will be further described with reference to the drawings and examples.
FIG. 1 is a block diagram of a real-time abrasion test device for a cardiovascular implant according to a preferred embodiment of the present invention;
FIG. 2 is a front view of a test module of a real-time abrasion test device for a cardiovascular implant according to a preferred embodiment of the present invention;
FIG. 3 is a cross-sectional view taken along the direction A-A in FIG. 2;
FIG. 4 is an enlarged view of portion B of FIG. 3;
FIG. 5 is an enlarged view of portion C of FIG. 3;
FIG. 6 is an exploded view of the energy buffer chamber portion of a cardiovascular implant real-time wear test device according to a preferred embodiment of the present invention;
FIG. 7 is an exploded view of the drive assembly portion of the real-time wear test device for a cardiovascular implant of the preferred embodiment of the present invention;
FIG. 8 is a block diagram of a fluid replacement module of a real-time abrasion test device for a cardiovascular implant according to a preferred embodiment of the present invention;
FIG. 9 is a block diagram of a camera module of a real-time abrasion test device for a cardiovascular implant according to a preferred embodiment of the present invention;
in the figure: the test module 1, the main board 11, the adjusting case 12, the independent inner chamber 13, the test tube 14, the return tube 15, the check valve I16, the check valve II17, the check valve sleeve 18, the exhaust cover 19, the exhaust valve I110, the liquid buffer tank 111, the energy buffer chamber 112, the observation window 113, the throttle valve 114, the throttle valve observation window 115, the elastic diaphragm 116, the spring 117, the damping adjustment valve 118, the through hole I119, the spring base 120, the through hole II121, the support rod I122, the exhaust valve II123, the voice coil motor 124, the sliding sleeve 125, the pushing member I126, the pushing member II127, the pushing member III128, the motor connecting sleeve 129, the motor support 130, the equipment box 131, the heating plate 132, the spacer 133, the pressure sensor 134, the water inlet valve 135, the drain valve 136, the water inlet 137, the fluid supplementing module 2, the case base 21, the pipe 22, the lower seat plate 23, the acryl cover 24, the upper cover 25, the support rod II26, the air valve 27, the cap 28, the water outlet valve 29, the camera module 3, the camera support 31, the high speed camera 32, the diaphragm 33, and the clamp 4.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, based on the embodiments of the invention, which are apparent to those of ordinary skill in the art without inventive faculty, are intended to be within the scope of the invention.
Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, based on the embodiments of the invention, which are apparent to those of ordinary skill in the art without inventive faculty, are intended to be within the scope of the invention.
As shown in fig. 1-9, a real-time abrasion test device for cardiovascular implant comprises a test module 1, a fluid infusion module 2 and a camera module 3, wherein the test module 1 comprises a main board 11, test components which respectively correspond to each independent inner cavity 13 in the main board 11 to form an independent test channel, and a driving component which is correspondingly connected with the test channel, and the test components comprise an adjusting box body 12, and a test tube 14 and a return tube 15 which are connected between the adjusting box body 12 and the corresponding independent inner cavity 13; the independent inner cavity 13 is internally provided with a one-way valve I16, the regulating box body 12 is internally provided with a one-way valve II17, and test liquid in the test channel flows out of the independent inner cavity 13 and flows through the test tube 14, the regulating box body 12 and the return tube 15 in sequence and then flows back into the corresponding independent inner cavity 13; a cardiovascular implant is placed within the trial tube 14; the fluid supplementing module 2 is connected with the test channel and is used for supplementing test fluid into the test channel; the camera module 3 can be arranged opposite to any adjusting box 12 to record the test condition in the test channel where the adjusting box 12 is located.
The average heartbeat frequency of the human body is about 1.2Hz, so that the frequency of the abrasion test device is controlled to be between 1 and 3.3Hz in order to be capable of highly simulating physiological conditions of the human body, in the low frequency range, the test liquid is required to completely pass through the valve sample placed in the test tube 14 in the process of pushing water by the driving component corresponding to each test channel, in the low frequency range of 1 to 3.3Hz, the test liquid is very easy to appear and still not reach the valve sample, and flows upwards in the independent cavity 13, so that a part of pushing water is wasted directly, and in order to compensate the defect, the driving component with higher power is required to generate larger pushing water, so that the waste of energy is easily caused, and the test liquid flowing upwards in the independent cavity 13 also has hydrodynamic influence on the test liquid flowing back from the return pipe 15, so that the accuracy of the test result is directly tested. Thus, the present application installs a one-way valve I16 in the separate lumen 13 that prevents the test liquid from flowing up.
Likewise, the test liquid in the liquid buffer box 111 falls back and the test liquid rebounded in the energy buffer cavity is subjected to hydrodynamic influence, so that part of the test liquid cannot flow back, the normal liquid circulation quantity is destroyed, the normal liquid circulation process is not met, the fallen liquid is used for punching the valve leaves of the valve sample, the valve sample is dithered in the closing process, the pressure curve at the outflow end of the valve sample vibrates greatly, and the test accuracy is directly influenced, therefore, in order to solve the problems, the check valve II17 is arranged in the regulating box 12, the test liquid flowing into the liquid buffer box 111 can be prevented from falling into the energy buffer cavity 112 when falling back through the arrangement of the check valve II17, and meanwhile, the phenomenon that the test liquid flows back to the outflow end of the valve sample when a driving assembly returns is avoided, so that the pressure curve before and after the valve sample is ensured to be stable is ensured.
Therefore, the arrangement of the one-way valve I16 and the one-way valve II17 enables the whole abrasion test device to simulate the normal pulsation of the heart of a human body and the mechanism of blood flow, provides a physiological environment which is highly similar to the human body for the abrasion test of the artificial heart valve, and ensures the reliability of test results.
As shown in fig. 3, in order for the check valve I16 to achieve the effect of preventing the test liquid from flowing up the independent inner chamber 13, the independent inner chamber 13 includes a communication chamber opposite the test tube 14 and the drive assembly, and a return chamber above the communication chamber, and the check valve I16 is installed in the return chamber by means of a check valve sleeve 18.
Preferably, the top of each independent cavity 13 is closed by a vent cover plate 19, and a vent valve I110 is arranged on the vent cover plate 19, so that when the test liquid is injected into the test channel, the gas in the test channel can be discharged through the vent valve I110.
In order to enable the check valve II17 to achieve the effect of preventing the test liquid in the liquid buffer tank 111 from falling back to the energy buffer chamber 112, the interior of the regulating tank body 12 comprises an observation chamber opposite to the test tube 14 and a circulation chamber above the observation chamber, and the check valve II17 is installed at the communication place of the circulation chamber and the observation chamber.
Specifically, the transparent observation window 113 is installed at one end of the observation cavity facing away from the test tube 14, and the camera module 3 can be placed outside the observation window 113, so that the valve sample of the test tube 14 can be intuitively seen, and the test condition of the valve sample can be conveniently recorded.
As shown in fig. 1 to 3, in order to achieve energy buffering for the liquid, the top of the regulating tank 12 is provided with a liquid buffer tank 111 which communicates with the inside thereof and is transparent.
In this embodiment, the liquid buffer tank 111 includes a transparent liquid housing installed above the adjustment tank 12, and a liquid cover plate covering the top of the liquid housing, and a support rod I122 is provided outside the liquid housing to ensure the stability of the liquid housing.
Preferably, the liquid cover plate is provided with an exhaust valve II123 so as to exhaust the gas in the test channel when the test liquid is injected into the test channel.
In the test process, part of test liquid passes through the one-way valve II17 and enters the liquid buffer box 111, so that the liquid level of the test liquid fluctuates to perform energy buffer.
Preferably, the liquid outer cover can be made of transparent acrylic materials, so that the liquid level change in the observation period can be conveniently observed.
Preferably, the outer wall of the liquid buffer tank 111 is provided with liquid level scales.
The liquid level in the liquid buffer box 111 is different in height, and the air amount in the liquid buffer box 111 is different, namely, the difficulty of air compression in the liquid buffer box 111 when the test liquid enters the liquid buffer box 111 in the test process is different, so that when the liquid is injected into the test channel before the test, the test requirements of different valve samples, different system pressure curves and different pressure values can be matched by adjusting the liquid level in the liquid buffer box 111.
As shown in fig. 3-4 and fig. 6, in order to store energy and then push the test liquid to flow back, an energy buffer cavity 112 is arranged at the bottom of the adjusting box body 12, an elastic diaphragm 116 is arranged between the energy buffer cavity 112 and the adjusting box body 12, and a spring 117 is arranged below the elastic diaphragm 116.
When the driving assembly pushes water, a part of test liquid flows down into the energy buffer cavity 112 after passing through the valve sample, so that the elastic diaphragm 116 is pushed to deform in the direction of the energy buffer cavity 112, the spring 117 is compressed, when the driving assembly returns, the spring 117 returns, and the elastic force during return can push the test liquid upwards through the elastic diaphragm 116, so that the test liquid passes through the one-way valve II17 and flows back into the corresponding independent cavity 13 from the return pipe 15 after entering the circulation cavity.
Because the physiological pressure curve values of the human body learned by different types of valve samples are different, the quantity of air in the energy buffer cavity 112 has great influence on the pressure in the test channel and the movement work of the driving component, the pushing water quantity required by the abrasion test is large, and when the stroke of the driving component is increased, the deformation quantity of the spring 117 becomes large, so that the service life of the spring 117 is influenced, the internal pressure of the test channel is increased, and the power of the driving component is increased, therefore, in order to solve the problem, the damping regulating valve 118 is arranged at the bottom of the energy buffer cavity 112, the through hole I119 is arranged on the damping regulating valve 118, the through hole II121 is arranged on the spring base 120 at the bottom of the spring 117, and the communication quantity between the through hole I119 and the through hole II121 can be regulated by rotating the damping regulating valve 118.
In this embodiment, the elastic diaphragm 116 is fixed between the energy buffer chamber 112 and the adjustment housing 12 by the diaphragm upper clamp 4, the diaphragm lower clamp 4, and the diaphragm nut, the top of the spring 117 is fixed in the diaphragm lower clamp 4, and the bottom is fixed on the spring base 120. The bottom of the energy buffer chamber 112 is provided with a threaded hole, and a damping adjustment valve 118 is installed in the threaded hole. Through-hole I119 is provided with two, and through-hole II121 is provided with six, through rotating damping governing valve 118, can adjust through-hole I119 and through-hole II121 the same volume, and this same volume then has decided the ability of energy buffer chamber 112 body buffering test liquid, has improved the uniformity and the reliability of the pressure curve change of every test liquid circulation simultaneously.
Specifically, the same amount of the through hole I119 and the through hole II121 is adjusted, so that the amount of air in the energy buffer cavity 112 can be adjusted, the complementation with the spring 117 is realized, the buffer capacity of the energy buffer cavity 112 is greatly improved, valve samples with different sizes are adapted, and the corresponding human physiological pressure curve values can be provided for different valve samples.
Preferably, the bottom of the damper 118 is provided with a knob to facilitate rotation thereof.
As shown in fig. 3, during the test, a part of the test liquid entering the regulating tank 12 flows down to the energy buffer chamber 112 and a part of the test liquid enters the liquid buffer chamber 111 upward, so that a throttle chamber opposite to the return pipe 15 is provided in the regulating tank 12, and a throttle valve 114 is installed in the throttle chamber and positioned at one side of the regulating tank 12.
The throttle chamber penetrates the adjusting box body 12, one end of the throttle chamber is correspondingly communicated with the return pipe 15, and a throttle valve observation window 115 is arranged at the other end of the throttle chamber so as to observe the condition of the throttle valve 114, and the throttle valve 114 extends into the throttle chamber from one side of the adjusting box body 12.
In the process of backward movement or backwater of the driving assembly, the liquid level in the liquid buffer tank 111 falls back, and the test liquid can only flow back through the throttle valve 114 due to the arrangement of the one-way valve II17, so that the backwater amount of the test liquid can be controlled through the throttle valve 114.
As shown in fig. 3, 5 and 7, the driving assembly is used for providing power for the test liquid to flow in the test channel, and comprises a driving element and a transmission assembly arranged between the driving element and the main plate 11.
The driving element may be, but is not limited to, a driving cylinder or voice coil motor 124, and in this embodiment the driving element is a voice coil motor 124.
Specifically, the voice coil motor 124 is fixed in the device case 131 through two motor brackets 130, and its output end faces the direction of the main board 11 and is connected to the main board 11 through a transmission assembly.
The abrasion test of the prosthetic heart valve requires a low frequency, i.e., 1-3.3Hz, large stroke (push water volume) to meet the valve sample opening and closing dynamics, and to achieve this, the transmission assembly includes a sliding sleeve 125, and a push member disposed within the sliding sleeve 125 and coupled to the power output of the drive element, the push member being capable of reciprocating within the sliding sleeve 125.
As shown in fig. 3 and 5, specifically, the pushing element is mounted on the guide rod of the voice coil motor 124, and sequentially includes a pushing element I126, a pushing element II127 and a pushing element III128 from the side where the voice coil motor 124 is located, where the pushing element I126 and the pushing element III128 are hard materials, the pushing element II127 is soft materials, the pushing element I126 and the pushing element III128 clamp the pushing element II127 in the middle, and one side of the pushing element II127 facing the pushing element II127 is in nested fit with the pushing element II127 to form an "H" structure, and perform a reciprocating motion in the sliding sleeve 125 during the test. Wherein, push away in the push away piece II127 direct with the inner wall contact of sliding sleeve 125, can reduce the contact surface between push away piece and the sliding sleeve 125 like this, make the less outer disc of push away piece II127 and the sliding sleeve 125 inner wall do frictional motion, increase push away the life of piece and sliding sleeve 125. Therefore, the pushing piece with the structure not only can ensure firm connection between the pushing piece and the guide rod, but also can ensure stability between the pushing piece II127 and the sliding sleeve 125, and simultaneously can reduce friction between the pushing piece and the sliding sleeve 125 and prolong service life of the pushing piece.
Specifically, the pushing element I126, the pushing element II127 and the pushing element III128 are fixed by screw connection, one end facing the main board 11 is fixed on a motor connecting sleeve 129, and the other end is fixed on a motor bracket 130. The guide rod of the voice coil motor 124 passes through the inner holes of the pushing piece I and the pushing piece II and is in threaded fit with the inner hole of the pushing piece III, and when the guide rod acts, the pushing piece can be driven to reciprocate in the sliding sleeve 125, so that test liquid in the test channel is driven to act, and the heart environment of a human body is simulated.
Preferably, the pushing piece II127 is made of a silicon rubber material, and the sliding sleeve 125 is made of a transparent acrylic material, so that friction between the sliding sleeve 125 and the pushing piece can be reduced, and the movement condition can be conveniently observed.
As shown in fig. 3, in order to make the temperature of the test liquid closer to the human body temperature, the main plate 11 is provided with a heating plate 132 toward the side of the driving unit, discharging the test effect due to the difference in ambient temperature.
Specifically, the heating plate 132 is fixed between the motor connecting sleeve 129 and the main board 11, the motor bracket 130 at the output end of the voice coil motor 124 is connected with the motor connecting sleeve 129 and the heating plate 132 through bolts, the heating plate 132 is connected with the main board 11 through bolts, and the inner holes of the sliding sleeve 125, the motor connecting sleeve 129 and the heating plate 132 are correspondingly communicated with the communicating cavity of the independent inner cavity 13.
The exterior of the heater plate 132 may be wrapped around a heater strip to heat the heater plate 132, the heater plate 132 transferring heat to the test liquid in its interior bore.
Preferably, the heating plate 132 is made of aviation aluminum material, which has good guidance.
The test tube 14 is used for preventing valve samples, and in order to facilitate the placement and the removal of valve samples, the test tube 14 has a two-section structure, the cardiovascular implant is placed in the corresponding clamp 4, and the clamp 4 is fixed at the joint of the two sections of the test tube 14.
Specifically, the test tube 14 includes an inflow tube and an outflow tube, the inflow tube is mounted on the main plate 11, the outflow tube is mounted on the regulating housing 12, opposite ends of the inflow tube and the outflow tube are provided with mounting cavities, valve samples are prevented from being in the corresponding jigs 4, and the jigs 4 are prevented from being in the mounting cavities, and test liquid can pass through the valve samples to test them.
Preferably, the outer side of the test tube 14 is provided with a raising bar 133 connected between the main board 11 and the adjustment box 12 for ensuring stability between the main board 11 and the adjustment box 12.
Preferably, pressure sensors 134 are mounted at the bottoms of the inflow and outflow tubes, respectively, to facilitate detection of the pressure values at the inflow and outflow ends of the valve sample.
In order to facilitate the disassembly of the inflow tube and the outflow tube, the valve sample is placed and taken out, and the return tube 15 has a telescopic tube structure with two or more sections being detachable.
In this embodiment, the return pipe 15 includes a return pipe I and a return pipe II sleeved at one end of the return pipe I, where the return pipe I can stretch and retract in the return pipe II to adjust the distance between the main board 11 and the adjusting box 12.
As shown in fig. 1 and 8, in order to be able to inject test liquid into each test channel, the liquid replenishing module 2 comprises a tank base 21 and a liquid reservoir arranged above the tank base 21, the liquid reservoir being connected to each test channel by a pipe 22.
In this embodiment, the liquid storage tank includes a lower seat plate 23 fixed on the box base 21, an acrylic outer cover 24 fixed on the lower seat plate 23, and an upper cover 25 covering the top of the acrylic outer cover 24, and a support bar II26 is disposed between the upper cover 25 and the lower seat plate 23 to ensure stability of the liquid storage tank.
Preferably, the upper cover 25 is provided with an air inlet and outlet valve 27 and a water inlet, and the water inlet is provided with a cap 28.
One side of the lower seat board 23 is provided with a water outlet valve 29, the water outlet valve 29 is connected with each water inlet valve 135 positioned at one side of the equipment box 131 through a pipeline 22, and each water inlet valve 135 is connected with a water inlet 137 corresponding to the bottom of the motor connecting sleeve 129 through a water pipe, so that test liquid can be conveniently injected into the test channel.
Preferably, the bottom of the conditioning tank 12 is provided with a drain valve 136 for draining the test liquid in the test channel.
As shown in fig. 1 and 9, in order to facilitate recording of the opening and closing condition of the valve sample, the camera module 3 includes a movable camera holder 31, and a high-speed camera 32 mounted on the camera holder 31, and a lens end of the high-speed camera 32 is provided with an aperture 33 fixed on the camera holder 31.
In the present embodiment, the camera module 3 is provided with one, and the requirement of observing each test channel is achieved by moving the camera mount 31.
In addition, a corresponding camera module 3 can be arranged at each adjusting box body 12 according to the requirement, so that the specific situation in the test process of each valve sample can be accurately recorded.
The high-speed camera 32 in the camera module 3 adopts a high-frame-rate visual industrial camera, is assisted by a light source, software and other control systems, and the lens is used for observing the opening and closing conditions of valve samples in a test channel through the observation window 113 and the test probability, and is connected to a computer through a data communication line to analyze, record and store the acquired data.
After the valve sample is mounted on the test tube 14 before the test is started, the test liquid can be injected into the test module 1. Firstly, the exhaust valve I110 and the exhaust valve II123 are opened, so that the air and the outside inside the whole test module 1 can normally and smoothly flow; filling test liquid into a liquid storage tank on the liquid filling module 2, opening a water inlet valve 135 and a water outlet valve 29, beginning to inject the test liquid into the test module 1, and closing an exhaust valve I110 and an exhaust valve II123 when the test liquid reaches a set height by observing the liquid level in the liquid buffer tank 111; the liquid can be supplemented or reduced in the liquid supplementing module 2 so as to change the basic pressure in the test system, thereby meeting the test requirement of the artificial heart valve in the clinical environment caused by the blood pressure in the human body.
At the beginning of the test, the voice coil motor 124 performs reciprocating circulation according to the rivet frequency of the human body of 1.2Hz or the test frequency of 3Hz, and the guide rod of the voice coil motor 124 pushes the pushing piece to perform reciprocating motion in the sliding sleeve 125 to simulate the heart environment. The test liquid pushes the valve sample to open and pass through the valve sample, part of the liquid reaches the energy buffer cavity 112, the elastic diaphragm 116 and the spring 117 receive energy generated by pushing the test liquid to flow, and the energy buffer cavity is subjected to transient deformation and serves as a component for temporarily storing energy; part of the test liquid passes through the one-way valve II17 and reaches the liquid buffer box 111 at the upper end, so that the liquid level of the test liquid fluctuates and is subjected to energy buffer. When the voice coil motor 124 makes a return motion, the valve sample is closed, the spring 117 and the elastic diaphragm 116 in the energy buffer cavity 112 start to release energy, and the test liquid passes through the one-way valve II17 and flows back to the corresponding independent inner cavity 13, namely the inflow end of the valve sample, through the return pipe 15 again. The voice coil motor 124 reciprocates in this way, and achieves the test fluid circulation, so that the artificial heart valve can be clinically represented as being opened and closed at a designated frequency, and the abrasion test of the artificial heart valve can be completed.
With the above-described preferred embodiments according to the present invention as an illustration, the above-described descriptions can be used by persons skilled in the relevant art to make various changes and modifications without departing from the scope of the technical idea of the present invention. The technical scope of the present invention is not limited to the description, but must be determined according to the scope of claims.
Claims (10)
1. A real-time abrasion test device for a cardiovascular implant, comprising
The test module (1) comprises a main board (11), test components which respectively correspond to each independent inner cavity (13) in the main board (11) to form an independent test channel, and a driving component which is correspondingly connected with the test channel, wherein the test components comprise an adjusting box body (12), and a test tube (14) and a return tube (15) which are connected between the adjusting box body (12) and the corresponding independent inner cavity (13);
the independent inner cavity (13) is internally provided with a one-way valve I (16), the regulating box body (12) is internally provided with a one-way valve II (17), and test liquid in the test channel flows out of the independent inner cavity (13) and sequentially flows through the test tube (14), the regulating box body (12) and the return tube (15) and then flows back into the corresponding independent inner cavity (13);
-the cardiovascular implant is placed inside the test tube (14);
a fluid supplementing module (2) connected with the test channel for supplementing test fluid into the test channel;
the camera module (3) can be arranged opposite to the optional adjusting box body (12) so as to record the test condition in the test channel where the adjusting box body (12) is positioned.
2. The real-time abrasion test device of a cardiovascular implant according to claim 1, characterized in that said independent inner cavity (13) comprises a communication cavity opposite to said test tube (14) and drive assembly, and a return cavity located above said communication cavity, said one-way valve I (16) being mounted in said return cavity by means of a one-way valve sleeve (18).
3. The real-time abrasion test device for cardiovascular implants according to claim 1, characterized in that the interior of said regulating box (12) comprises an observation chamber opposite to said test tube (14), and a circulation chamber located above said observation chamber, said one-way valve II (17) being mounted in communication with said observation chamber.
4. The real-time abrasion test device for cardiovascular implants according to claim 1, characterized in that the top of said regulating tank (12) is provided with a transparent liquid buffer tank (111) communicating with the inside thereof.
5. The cardiovascular implant real-time wear test device according to claim 1, wherein an energy buffer cavity (112) is arranged at the bottom of the adjusting box body (12), an elastic diaphragm (116) is arranged between the energy buffer cavity (112) and the adjusting box body (12), and a spring (117) is arranged below the elastic diaphragm (116);
the damping adjusting valve (118) is installed at the bottom of the energy buffering cavity (112), a through hole I (119) is formed in the damping adjusting valve (118), a through hole II (121) is formed in a spring base (120) at the bottom of the spring (117), and the damping adjusting valve (118) can be rotated to adjust the communication quantity between the through hole I (119) and the through hole II (121).
6. The real-time abrasion test device for cardiovascular implants according to claim 1, characterized in that a throttle chamber opposite to the return pipe (15) is arranged inside the regulating box body (12), and a throttle valve (114) positioned on one side of the regulating box body (12) is arranged in the throttle chamber.
7. The cardiovascular implant real-time wear test device according to claim 1, characterized in that the drive assembly comprises a drive element, and a transmission assembly arranged between the drive element and the main plate (11);
the transmission assembly comprises a sliding sleeve (125) and a pushing piece which is arranged in the sliding sleeve (125) and is connected with the power output end of the driving element, and the pushing piece can reciprocate in the sliding sleeve (125).
8. The cardiovascular implant real-time wear test device according to claim 1, characterized in that the side of the main plate (11) facing the drive assembly is provided with a heating plate (132);
the test tube (14) is of a two-section structure, the cardiovascular implant is placed in a corresponding clamp (4), and the clamp (4) is fixed at the joint of the two sections of the test tube (14);
the return pipe (15) is of a telescopic sleeve structure with two or more sections which can be detached.
9. The real-time abrasion test device for cardiovascular implants according to claim 1, characterized in that said fluid infusion module (2) comprises a tank base (21), and a reservoir provided above said tank base (21), said reservoir being connected to each test channel by a pipe.
10. The real-time abrasion test device of cardiovascular implants according to claim 1, characterized in that said camera module (3) comprises a movable camera support (31), and a high-speed camera (32) mounted on said camera support (31), the lens end of said high-speed camera (32) being provided with an aperture (33) fixed on said camera support (31).
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| CN202410167192.9A CN117705560B (en) | 2024-02-06 | 2024-02-06 | Real-time abrasion test device for cardiovascular implant |
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Citations (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1068031A (en) * | 1991-06-26 | 1993-01-20 | 清华大学 | A kind of Cardiac valve prosthesis fatigue life test method and device |
| CA2140642A1 (en) * | 1992-08-12 | 1994-03-03 | Joseph S. Danon | Oxygen breathing controls |
| DE202004001960U1 (en) * | 2004-02-09 | 2004-06-17 | F + E Ingenieurgesellschaft mbH für Energieberatung und Festigkeitsanalyse | Component vibration test stand can insert elastic medium in drive path to vary spring constant of gas spring with eccentric drive |
| US20070185571A1 (en) * | 2006-02-06 | 2007-08-09 | The Cleveland Clinic Foundation | Apparatus and method for treating a regurgitant valve |
| CN201268704Y (en) * | 2008-09-26 | 2009-07-08 | 中国人民解放军第四军医大学 | Dynamic bionic pulsating movement bioreactor |
| AU2009202750A1 (en) * | 2008-07-10 | 2010-01-28 | Bernard Lionel Gien | Pneumatic drill |
| US20100225478A1 (en) * | 2009-03-06 | 2010-09-09 | Biomedical Device Consultants and Laboratories of Colorado, LLC | Fatigue testing system for prosthetic devices |
| US20110303026A1 (en) * | 2010-06-14 | 2011-12-15 | Shouyan Lee | Portable multifunction cardiac simulator and heart valve tester |
| CN103622763A (en) * | 2012-08-28 | 2014-03-12 | 苏州爱尔博生物医学工程产品研发有限公司 | Valve fatigue-life testing device |
| CN209332384U (en) * | 2018-12-08 | 2019-09-03 | 北京市普惠生物医学工程有限公司 | A kind of heart valve prosthesis stable state leakage current experimental rig |
| CN111789700A (en) * | 2020-06-30 | 2020-10-20 | 成都赛拉诺医疗科技有限公司 | Valve function testing device |
| CN215115677U (en) * | 2021-06-23 | 2021-12-10 | 上海盈阁智能科技有限公司 | Artificial valve fatigue tester |
| CN113925647A (en) * | 2021-11-23 | 2022-01-14 | 兰州理工大学 | Artificial heart valve extracorporeal circulation pulsating flow experimental system and experimental method |
| US20220053662A1 (en) * | 2020-08-14 | 2022-02-17 | Beehe ( Taicang ) Electric Co., Ltd. | Pump drive device |
| CN115389352A (en) * | 2022-10-27 | 2022-11-25 | 圣塔菲医疗科技(常州)有限公司 | Cardiovascular implant fatigue test device |
| CN115541404A (en) * | 2022-12-05 | 2022-12-30 | 圣塔菲医疗科技(常州)有限公司 | Cardiovascular implant fatigue testing machine |
| CN218444453U (en) * | 2022-10-27 | 2023-02-03 | 圣塔菲医疗科技(常州)有限公司 | Circulation mechanism of fatigue testing machine for cardiovascular implant |
| CN218629033U (en) * | 2022-12-05 | 2023-03-14 | 圣塔菲医疗科技(常州)有限公司 | Cardiovascular implant fatigue test system |
| CN115901302A (en) * | 2022-11-14 | 2023-04-04 | 上海心瓣测试设备有限公司 | Modularized human heart valve pulsating flow performance testing machine |
| CN219122861U (en) * | 2022-12-02 | 2023-06-02 | 上海臻亿医疗科技有限公司 | In-vitro simulation testing device |
| CN116718498A (en) * | 2023-08-08 | 2023-09-08 | 圣塔菲医疗科技(常州)有限公司 | Cardiovascular implant fatigue testing machine |
-
2024
- 2024-02-06 CN CN202410167192.9A patent/CN117705560B/en active Active
Patent Citations (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1068031A (en) * | 1991-06-26 | 1993-01-20 | 清华大学 | A kind of Cardiac valve prosthesis fatigue life test method and device |
| CA2140642A1 (en) * | 1992-08-12 | 1994-03-03 | Joseph S. Danon | Oxygen breathing controls |
| DE202004001960U1 (en) * | 2004-02-09 | 2004-06-17 | F + E Ingenieurgesellschaft mbH für Energieberatung und Festigkeitsanalyse | Component vibration test stand can insert elastic medium in drive path to vary spring constant of gas spring with eccentric drive |
| US20070185571A1 (en) * | 2006-02-06 | 2007-08-09 | The Cleveland Clinic Foundation | Apparatus and method for treating a regurgitant valve |
| AU2009202750A1 (en) * | 2008-07-10 | 2010-01-28 | Bernard Lionel Gien | Pneumatic drill |
| CN201268704Y (en) * | 2008-09-26 | 2009-07-08 | 中国人民解放军第四军医大学 | Dynamic bionic pulsating movement bioreactor |
| US20100225478A1 (en) * | 2009-03-06 | 2010-09-09 | Biomedical Device Consultants and Laboratories of Colorado, LLC | Fatigue testing system for prosthetic devices |
| US20110303026A1 (en) * | 2010-06-14 | 2011-12-15 | Shouyan Lee | Portable multifunction cardiac simulator and heart valve tester |
| CN103622763A (en) * | 2012-08-28 | 2014-03-12 | 苏州爱尔博生物医学工程产品研发有限公司 | Valve fatigue-life testing device |
| CN209332384U (en) * | 2018-12-08 | 2019-09-03 | 北京市普惠生物医学工程有限公司 | A kind of heart valve prosthesis stable state leakage current experimental rig |
| CN111789700A (en) * | 2020-06-30 | 2020-10-20 | 成都赛拉诺医疗科技有限公司 | Valve function testing device |
| US20220053662A1 (en) * | 2020-08-14 | 2022-02-17 | Beehe ( Taicang ) Electric Co., Ltd. | Pump drive device |
| CN215115677U (en) * | 2021-06-23 | 2021-12-10 | 上海盈阁智能科技有限公司 | Artificial valve fatigue tester |
| CN113925647A (en) * | 2021-11-23 | 2022-01-14 | 兰州理工大学 | Artificial heart valve extracorporeal circulation pulsating flow experimental system and experimental method |
| CN115389352A (en) * | 2022-10-27 | 2022-11-25 | 圣塔菲医疗科技(常州)有限公司 | Cardiovascular implant fatigue test device |
| CN218444453U (en) * | 2022-10-27 | 2023-02-03 | 圣塔菲医疗科技(常州)有限公司 | Circulation mechanism of fatigue testing machine for cardiovascular implant |
| CN115901302A (en) * | 2022-11-14 | 2023-04-04 | 上海心瓣测试设备有限公司 | Modularized human heart valve pulsating flow performance testing machine |
| CN219122861U (en) * | 2022-12-02 | 2023-06-02 | 上海臻亿医疗科技有限公司 | In-vitro simulation testing device |
| CN115541404A (en) * | 2022-12-05 | 2022-12-30 | 圣塔菲医疗科技(常州)有限公司 | Cardiovascular implant fatigue testing machine |
| CN218629033U (en) * | 2022-12-05 | 2023-03-14 | 圣塔菲医疗科技(常州)有限公司 | Cardiovascular implant fatigue test system |
| CN116718498A (en) * | 2023-08-08 | 2023-09-08 | 圣塔菲医疗科技(常州)有限公司 | Cardiovascular implant fatigue testing machine |
Non-Patent Citations (1)
| Title |
|---|
| 赵乐军, 陆颂芳, 奚廷斐: "人工心脏瓣膜脉动流检测技术研究", 透析与人工器官, no. 03, 30 September 2002 (2002-09-30), pages 40 - 43 * |
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