CN117695527A - Cornea crosslinking system - Google Patents
Cornea crosslinking system Download PDFInfo
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- CN117695527A CN117695527A CN202410073022.4A CN202410073022A CN117695527A CN 117695527 A CN117695527 A CN 117695527A CN 202410073022 A CN202410073022 A CN 202410073022A CN 117695527 A CN117695527 A CN 117695527A
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- 238000004132 cross linking Methods 0.000 title claims abstract description 69
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- 238000010168 coupling process Methods 0.000 claims abstract description 26
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- 210000003786 sclera Anatomy 0.000 claims abstract description 20
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- 238000000034 method Methods 0.000 abstract description 7
- 230000008569 process Effects 0.000 abstract description 7
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- 210000005252 bulbus oculi Anatomy 0.000 description 4
- 201000002287 Keratoconus Diseases 0.000 description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
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- 108010035532 Collagen Proteins 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
- A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
- A61N2005/0645—Applicators worn by the patient
- A61N2005/0647—Applicators worn by the patient the applicator adapted to be worn on the head
- A61N2005/0648—Applicators worn by the patient the applicator adapted to be worn on the head the light being directed to the eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0661—Radiation therapy using light characterised by the wavelength of light used ultraviolet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0664—Details
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
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- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Eye Examination Apparatus (AREA)
Abstract
The utility model discloses a cornea crosslinking system, and belongs to the technical field of medical appliances. The cornea crosslinking system comprises a light source, an outer shell, a light guide module, a position measuring module and a controller, wherein the light guide module and the position measuring module are arranged in the outer shell. The light guide module is used for transmitting light emitted by the light source to the eye surface of the patient, and is provided with an abutting surface abutting against the cornea and the sclera of the eye surface of the patient and a coupling surface coupled with the light source. The position measurement module is coupled with the light guide module and arranged on a coupling surface of the light guide module, and is configured to acquire relative position information of the light guide module and the cornea. The controller is in communication connection with the position measurement module, receives the relative position information from the position measurement module and obtains the position offset information of the light guide module relative to the cornea based on the relative position information. The cornea crosslinking system adopted by the utility model can measure the position deviation information of the light guide module relative to the cornea, thereby being beneficial to realizing the accurate control of the cornea crosslinking process.
Description
The present application is a divisional application of application number 202311511892.7, application day 2023, 11, 14, and application name "a cornea crosslinking assist device and cornea crosslinking system" by super-eye technologies (Beijing) limited.
Technical Field
The utility model relates to the technical field of medical instruments, in particular to a cornea crosslinking system.
Background
The principle of cornea crosslinking is that riboflavin is used as a photosensitizer, ultraviolet rays with a special wavelength are used for irradiating cornea local, collagen fibers are stimulated to carry out crosslinking reaction, the biomechanical property of cornea is improved, the development of keratoconus lesions can be effectively controlled, the vision is stabilized, and complications caused by cornea transplantation are avoided. The cornea shape can be changed to treat refraction problems such as myopia and hyperopia, or reduce astigmatism and irregularly contained light, and can also form multifocal cornea shape to enable the cornea to have high spherical aberration or multifocal, so as to achieve the purpose of treating presbyopia. However, the prior art has limited control capability on the cornea crosslinking process, and it is difficult to precisely control the cornea crosslinking process, so that it is difficult to precisely shape the crosslinked cornea. The cornea crosslinking instrument in the prior art controls the crosslinking degree by controlling the illumination intensity through the contact lens at the tail end close to the cornea, and changes the cornea morphology.
The utility model patent with the application number of CN201921276386.3 is a cornea crosslinking device with digital light treatment, wherein a plurality of rectangular cavities are arranged in the cover body, and ultraviolet light sources are arranged in the rectangular cavities. The utility model patent with the application number of CN202221916809.5 discloses a light-emitting device for cornea crosslinking, and a plurality of light-emitting units are arranged in an array manner in a light-emitting cover. According to the technical scheme, the relative position between the light source and the cornea is required to be kept static, when the eyeball rotates, the relative position between the light source and the cornea changes, so that the shaping position is offset, and the crosslinking precision is reduced. Therefore, there is a need to develop a device that can measure the displacement between a contact lens and the cornea in real time.
Disclosure of Invention
The utility model aims to provide a cornea crosslinking system which can measure the position deviation information of a light guide module relative to a cornea, thereby being beneficial to realizing the accurate control of the cornea crosslinking process.
To achieve the above object, the present utility model provides a cornea crosslinking system comprising:
a light source;
an outer housing;
a light guide module disposed in the outer housing, the light guide module configured to conduct light emitted by the light source to a patient's ocular surface, the light guide module configured with an abutment surface for abutting against a cornea and a sclera of the patient's ocular surface and a coupling surface for coupling with the light source;
the position measurement module is arranged in the outer shell, is coupled with the light guide module and is arranged on a coupling surface of the light guide module, and is configured to acquire relative position information of the light guide module and cornea;
and the controller is in communication connection with the position measurement module and is configured to receive the relative position information from the position measurement module and acquire the position offset information of the light guide module relative to the cornea based on the relative position information.
In one embodiment, the outer shell is configured in a cylindrical shape, the light guide module includes a plurality of light pipes, the light pipes are closely arranged along a central axis of the outer shell and are fixedly bundled, one ends of the light pipes form the abutting surface, and the other ends of the light pipes form the coupling surface.
In one embodiment, the abutment surface comprises:
an optical zone provided in a central region of the contact surface, configured to fit a central structure of the cornea and transmit incident light, the optical zone having a coverage area equal to or greater than the cornea area;
the contact area is arranged around the peripheral area of the optical area and is configured to be abutted against the sclera, and the curvature radius of the contact area gradually decreases along with the distance from the optical area.
In one embodiment, the light source is disposed in a central region of the coupling surface of the light guide module, the position measurement module is disposed in an edge region of the coupling surface of the light guide module, and a position projected onto the abutment surface by the position measurement module corresponds to a scleral region.
In one embodiment, the position measurement module comprises several sets of displacement measurement units, any one of the sets of displacement measurement units comprising:
the position of the light-emitting diode projected onto the abutting surface corresponds to the sclera area, and the light rays emitted by the light-emitting diode are conducted to the eye surface of the patient through the light guide module;
the optical sensor acquires a reflected light image of the light emitted by the light emitting diode reflected back from the eye surface of the patient through the light guide module;
the controller is in communication with the optical sensor and is configured to receive the reflected light image from the optical sensor and to obtain positional offset information of the light guide module relative to the cornea based on the reflected light image.
In one embodiment, the number of groups of the displacement measurement units is n, n being equal to or greater than 3.
In one embodiment, the plurality of groups of displacement measuring units are uniformly distributed in the edge area of the coupling surface along the circumferential direction.
In one embodiment, the controller is configured to control the movement of the light source and/or the outer housing and/or to control the turning on and/or off of the light source based on positional offset information of the light guide module relative to the cornea.
In one embodiment, the corneal crosslinking system comprises a movement module for moving the outer shell, and the controller is in communication with the movement module and configured to control the movement module based on the positional offset information.
In one embodiment, the light source is configured with a light source moving module for driving the light source to move, and the controller is in communication connection with the light source moving module and is configured for controlling the light source moving module based on the position offset information.
In one embodiment, the controller includes:
the information processing module is in communication connection with the position measurement module and is configured to receive the relative position information from the position measurement module and acquire the position offset information of the light guide module relative to the cornea based on the relative position information;
the data processing module is in communication connection with the information processing module and is configured to receive the position offset information from the information processing module, convert the position offset information into an offset value according to a set rule, compare the offset value with a set offset threshold value and output a comparison result;
and the control module is in communication connection with the data processing module and is configured to receive the comparison result from the data processing module and control the movement of the light source and/or the outer shell body based on the comparison result so that the relative positions of the light source, the light guide module and the cornea are kept unchanged and incident light is vertically conducted to the eye surface of the patient.
In one embodiment, the cornea crosslinking system further comprises an alarm reminding module, and the controller is in communication connection with the alarm reminding module and is configured to control the alarm reminding module to send out an alarm reminding based on the position deviation information.
Therefore, the cornea crosslinking system adopted by the utility model can carry out ultraviolet irradiation treatment on the cornea of a patient through the optical area of the light guide tube, so that the cornea is crosslinked, the contact area of the light guide tube is abutted against the sclera, and the position measuring module arranged on the coupling surface of the light guide tube can measure the position deviation information of the light guide module relative to the cornea. Through the system, accurate control on the cornea crosslinking process is realized, and even if eyeballs of a patient rotate in the crosslinking process, the relative position between the light source and the cornea can be kept still, so that the cornea shaping precision is ensured.
The technical scheme of the utility model is further described in detail through the drawings and the embodiments.
Drawings
FIG. 1 is a schematic view of a cornea crosslinking assist apparatus according to an embodiment of the present utility model;
FIG. 2 is a schematic diagram of a coupling surface structure according to an embodiment of the present utility model;
fig. 3 is a logic architecture diagram of a corneal crosslinking system in accordance with an embodiment of the present utility model.
Reference numerals
1. An outer housing; 2. a light source; 3. a displacement measuring unit; 31. an optical sensor; 32. a light emitting diode; 4. a light pipe; 5. cornea; 6. sclera; 7. a contact region; 8. an optical zone.
Detailed Description
The technical scheme of the utility model is further described below through the attached drawings and the embodiments.
Examples
As shown in fig. 1, a cornea crosslinking assisting apparatus includes a light guide module, a position measuring module, and an information processing module. The periphery of the cornea crosslinking auxiliary device is provided with a cylindrical outer shell 1 which has the functions of protection and fixation.
The light guide module capable of transmitting light comprises a plurality of light guide pipes 4, and the light guide pipes 4 are made of optical fiber materials. The light pipes 4 are arranged in a cylindrical shape along the same direction of the incident light, and are consolidated into a beam. The light pipe 4 can respectively form an abutting surface and a coupling surface through the annular structure and two end surfaces of the light pipe 4, the abutting surface is positioned at one end of the light pipe, and the coupling surface is positioned at the other end of the light pipe. The abutting surface is in contact with the cornea 5 and abuts against the cornea 5 or the sclera 6, and the coupling surface faces the light source 2 and is coupled with the light source 2; incident light emitted by the light source 2 is vertically transmitted to the surface of the eye of the patient through the coupling surface, the light guide module and the abutting surface in sequence.
As shown in fig. 2, the abutment surface comprises an optical zone 8 and a contact zone 7. The optical zone 8 is arranged in the central area of the contact surface, is configured to be matched with the central structure of the cornea 5 and transmit incident light, and the optical zone 8 is spherical or approximately spherical; the coverage area of the optical zone 8 is greater than or equal to the area of the cornea 5; the contact area 7 is arranged around the peripheral area of the optical area 8 and is abutted against the sclera 6, so that the cornea crosslinking auxiliary device and the optical area 8 thereof are positioned relative to the cornea, and the optical area 8 is fixed to a certain extent. Since the normal shape of the cornea gradually develops into a conical shape due to the lesion of the patient's eyeball, the radius of curvature of the contact region 7 is further gradually reduced as it is far from the optical region 8 in order to ensure a match with the keratoconus structure and to facilitate positioning.
In the human eyeball, the cornea 5 is slightly protruded from the sclera 6, the outer surface of the sclera 6 is wrapped by fascia and conjunctiva, the front edge is adjacent to the limbus, and the rear edge is continued to the optic nerve dura mater sheath. The surface layer of the sclera 6 is made of loose connective tissue, is tough, is connected with fascia layers, and has rich nerves and blood vessels. When the cornea 5 is crosslinked, ultraviolet light acts on the cornea 5 through the optical zone 8, so that the cornea 5 is ensured to be in the irradiation range of the ultraviolet light, the edge of the contact zone 7 is lapped on the surface layer of the sclera 6, the cornea 5 can be prevented from being damaged, and a foundation and a reference support are provided for realizing displacement measurement.
The position measurement module is arranged in the edge area of the coupling surface and is coupled with the light guide module, and is configured to acquire the relative position information of the light guide module and the cornea 5 in real time; the position measurement module comprises a plurality of groups of displacement measurement units 3, any group of displacement measurement units 3 comprises a light emitting diode 32 and an optical sensor 31, the light emitting diode 32 and the optical sensor 31 are arranged on a coupling surface, the position of the light emitting diode 32 projected onto the abutting surface is located in the range of the contact area 7, and light rays emitted by the light emitting diode 32 are transmitted to the ocular surface through a light pipe 4; the optical sensor 31 acquires reflected light images of light rays emitted by the light emitting diode 32 reflected by the eye surface in real time through the light guide 4, so that the movement condition of the position measuring module relative to the eye surface can be detected. Among them, the optical sensor 31 may be a semiconductor (CMOS) sensor whose surface is configured as a complementary metal oxide.
The optical sensor 31 is electrically connected to the light emitting diode 32, is in communication connection with the information processing module, and transmits the acquired reflected light image to the information processing module for processing and analysis, so as to obtain the positional deviation information of the light guide module relative to the cornea 5 at the spatial level, wherein the deviation information includes, but is not limited to, the deviation direction, the deviation angle and the deviation distance.
Wherein the group number of the displacement measuring units 3 is n, n is more than or equal to 3, and the displacement measuring units are uniformly distributed on the edge of the coupling surface along the circumferential direction. If the displacement measuring cells 3 are placed in a single group or unevenly, the optical sensors 31 are placed on one side, then when the crosslinking aid is moved relatively much with respect to the cornea of the patient, it is likely that all of the optical sensors 31 have moved to the surface of the cornea rather than on the sclera, resulting in a large measurement error.
If the displacement measuring units 3 are arranged in two groups and symmetrically arranged, when the crosslinking auxiliary device moves relative to the cornea of a patient, although the projection of at least one optical sensor 31 can be ensured to be positioned on the surface of the sclera and work normally, once the displacement measuring units 3 rotate around the second optical sensor 31, only one optical sensor 31 can measure data, the rotation is insensitive, and the measurement accuracy can be affected.
If the displacement measuring cells 3 are arranged in 3 groups but are unevenly distributed, it is necessary that the two groups are relatively close. Further, when the distance is small, the two sets of displacement measuring units 3 may be regarded as one set, that is, two sets of displacement measuring units 3 are provided.
Therefore, the number n of groups of the displacement measuring units 3 is at least three, and is preferably uniformly distributed.
By combining the smooth and transparent tissue characteristics of the cornea and the structural characteristics of rough and white sclera, the projection of any group of displacement measuring units 3 is positioned on the sclera 6 of the patient's eye, so that the optical sensor 31 can more effectively acquire the reflected light image of the light emitted by the light emitting diode 32 reflected by the surface of the eye, and the problem of light leakage caused by the fact that the projection of the optical sensor 31 is positioned on the cornea of the patient is avoided. The specific displacement deviation direction and deviation value of the crosslinking auxiliary device relative to the eye surface of the patient can be determined through the comprehensive positioning results of the plurality of groups of displacement measuring units 3.
The information processing module is in communication connection with the position measuring module, receives the relative position information and measures the position deviation information of the light guide module relative to the cornea 5 in real time. Specifically, in this embodiment, the information processing module may be a Digital Signal Processor (DSP).
A cornea crosslinking system has a logic structure as shown in figure 3, and comprises a light source 2, a cornea crosslinking auxiliary device, a data processing module, a control module, a light source moving module, an auxiliary device moving module and an alarm reminding module.
The light source 2 needs to be adapted to illuminate the cornea 5 of the patient's eye.
The corneal crosslinking aid is coupled to the light source 2 as previously shown.
The data processing module is in communication connection with the cornea crosslinking auxiliary device, receives the position deviation information of the cornea crosslinking auxiliary device relative to the cornea 5, converts the position deviation information into a deviation value according to a set rule, compares the deviation value with a set deviation threshold value, and outputs a comparison result.
The control module receives the comparison result output by the data processing module, controls the light source 2 and/or the cornea crosslinking auxiliary device to move or stop based on the comparison result, and controls the light source 2 to be turned on and/or turned off; the control module is respectively connected with the light source 2, the cornea crosslinking auxiliary device and the data processing module in a communication way.
In this embodiment, the light source 2 may project a specific graphic image onto the cornea using ultraviolet light to form a crosslink of a specified intensity at a specified location, thereby changing the morphology and refractive power of the cornea's local area.
The light source 2 is configured with a light source moving module (not shown) that can take a variety of combinations including, but not limited to, motor-coupled ball screw, motor, gear set-coupled slider/slide rail, electromagnetic power-coupled track, multi-motor-driven multi-direction, multi-degree of freedom arm, etc., and will not be described in detail herein. The light source 2 can freely move along the light source moving module, so that incident light emitted by the light source 2 is ensured to vertically enter the cornea crosslinking auxiliary device.
The corneal crosslinking aid is provided with an aid movement module (not shown) along which the corneal crosslinking aid can be freely moved to vertically conduct incident light emitted from the light source 2 to the surface of the patient's eye. The auxiliary device moving module can select a proper power combination corresponding to the light source moving module, and the specific selection can be designed according to actual needs.
The light source moving module and the auxiliary device moving module are respectively in communication connection with the control module. The movement forms of the light source moving module and the auxiliary device moving module include, but are not limited to, a ball screw, an electric push rod, a linear motor, a gear rack and the like, and are loaded on a bracket so as to realize the free movement of the cornea 5 crosslinking device and the light source 2 in an adjustable range.
In this embodiment, when the comparison result between the offset value and the set offset threshold in the data processing module is negative, it indicates that the deviation degree of the contact surface and the ocular surface is within the allowable range, and at this time, the control module controls the light source 2 to freely move along the light source moving module, and controls the cornea crosslinking auxiliary device to freely move along the auxiliary device moving module, so that the relative positions of the light source 2, the cornea crosslinking auxiliary device and the cornea 5 remain unchanged and the incident light is vertically transmitted to the ocular surface of the patient. The offset threshold may be set to a specific offset value (± Xmm, ymm, Z °) based on different patient eye parameters and their corresponding surgical targets, may also be set to an area percentage of the reference, may even be set to an overlap ratio of the abutment surface with respect to the cornea, or may be otherwise executable.
The cornea 5 crosslinking system further comprises a warning reminding module which is in communication connection with the control module, when the comparison result is positive, the deviation degree of the abutting surface and the eye table is too large, the deviation degree exceeds the adjusting range, the warning reminding module sends out warning reminding, and the control module controls the light source 2 to be turned off.
Specifically, the offset threshold may be set to be 30% of the corneal area away from the cornea. When the abutting surface in the cornea crosslinking auxiliary device deviates from the cornea of the patient, the data processing module receives the position deviation information of the cornea crosslinking auxiliary device relative to the cornea 5, calculates the deviation amount as the relative cornea area, and compares a% with the deviation threshold value of 70% of the cornea area. If a percent is less than or equal to 30 percent, the control module controls the ultraviolet projection image to freely move along the light source moving module and controls the cornea crosslinking auxiliary device to freely move along the auxiliary device moving module, so that the relative positions of the ultraviolet projection image, the cornea crosslinking auxiliary device and the cornea 5 are kept unchanged and the incident light is vertically conducted to the eye surface of the patient.
If a percent is more than 30 percent, the displacement is overlarge, the part of the abutting surface, which is overlapped with the cornea, is smaller than the minimum value of the operation requirement, the control module sends a signal to the warning and reminding module, and the warning and reminding module sends a warning including but not limited to buzzing, sensitive light stimulation and the like, synchronously cuts off the ultraviolet projection image, and reminds doctors of being capable of performing intervention and correction.
Therefore, according to the cornea crosslinking auxiliary device and the cornea 5 crosslinking system with the above structures, the cornea 5 of a patient can be subjected to ultraviolet irradiation treatment through the optical zone 8 of the light guide tube 4, so that the cornea 5 is crosslinked, the contact zone 7 of the light guide tube 4 is abutted against the sclera 6, and the position measurement module arranged on the coupling surface of the light guide tube 4 can measure the position deviation information of the light guide module relative to the cornea 5; the cornea 5 crosslinking system comprises a cornea crosslinking device, an adaptive light source 2, a data processing module and a control module, wherein the control module controls the cornea crosslinking auxiliary device to move or stop according to the position deviation information obtained by the data processing module, and controls the light source 2 to be turned on and/or off. The device and the system realize the precise control of the crosslinking process of the cornea 5, and improve the accuracy of the crosslinking on the diopter control of the cornea.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present utility model and not for limiting it, and although the present utility model has been described in detail with reference to the preferred embodiments, it will be understood by those skilled in the art that: the technical scheme of the utility model can be modified or replaced by the same, and the modified technical scheme cannot deviate from the spirit and scope of the technical scheme of the utility model.
Claims (10)
1. A corneal crosslinking system, comprising:
a light source;
an outer housing;
a light guide module disposed in the outer housing, the light guide module configured to conduct light emitted by the light source to a patient's ocular surface, the light guide module configured with an abutment surface for abutting against a cornea and a sclera of the patient's ocular surface and a coupling surface for coupling with the light source;
the position measurement module is arranged in the outer shell, is coupled with the light guide module and is arranged on a coupling surface of the light guide module, and is configured to acquire relative position information of the light guide module and cornea;
and the controller is in communication connection with the position measurement module and is configured to receive the relative position information from the position measurement module and acquire the position offset information of the light guide module relative to the cornea based on the relative position information.
2. The cornea crosslinking system of claim 1, wherein the outer housing is configured in a cylindrical shape, the light guide module comprises a plurality of light pipes, the plurality of light pipes are closely arranged along a central axis of the outer housing and are fixedly bundled, one ends of the plurality of light pipes form the abutting surface, and the other ends of the plurality of light pipes form the coupling surface.
3. The corneal crosslinking system of claim 1 or 2, wherein the abutment surface comprises:
an optical zone provided in a central region of the contact surface, configured to fit a central structure of the cornea and transmit incident light, the optical zone having a coverage area equal to or greater than the cornea area;
the contact area is arranged around the peripheral area of the optical area and is configured to be abutted against the sclera, and the curvature radius of the contact area gradually decreases along with the distance from the optical area.
4. The corneal crosslinking system of claim 1, wherein the light source is disposed in a central region of the coupling surface of the light guide module, the position measurement module is disposed in an edge region of the coupling surface of the light guide module, and a position projected onto the abutment surface by the position measurement module corresponds to a scleral region.
5. The corneal crosslinking system of claim 1, wherein the position measurement module comprises a plurality of sets of displacement measurement units, any one set of displacement measurement units comprising:
the position of the light-emitting diode projected onto the abutting surface corresponds to the sclera area, and the light rays emitted by the light-emitting diode are conducted to the eye surface of the patient through the light guide module;
the optical sensor acquires a reflected light image of the light emitted by the light emitting diode reflected back from the eye surface of the patient through the light guide module;
the controller is in communication with the optical sensor and is configured to receive the reflected light image from the optical sensor and to obtain positional offset information of the light guide module relative to the cornea based on the reflected light image.
6. The cornea crosslinking system of claim 5, wherein the displacement measurement units have a group number of n, n being greater than or equal to 3; and/or
The displacement measuring units are uniformly distributed in the edge area of the coupling surface along the circumferential direction.
7. The corneal crosslinking system of claim 1, wherein the controller is configured to control movement of the light source and/or the outer housing and/or to control turning on and/or off of the light source based on positional offset information of the light guide module relative to the cornea.
8. The corneal crosslinking system of claim 7, comprising a movement module for moving the outer shell, the controller communicatively coupled to the movement module and configured to control the movement module based on the positional offset information; and/or
The light source is configured with a light source moving module for driving the light source to move, and the controller is in communication connection with the light source moving module and is configured for controlling the light source moving module based on the position offset information.
9. The corneal crosslinking system of claim 7, wherein the controller comprises:
the information processing module is in communication connection with the position measurement module and is configured to receive the relative position information from the position measurement module and acquire the position offset information of the light guide module relative to the cornea based on the relative position information;
the data processing module is in communication connection with the information processing module and is configured to receive the position offset information from the information processing module, convert the position offset information into an offset value according to a set rule, compare the offset value with a set offset threshold value and output a comparison result;
and the control module is in communication connection with the data processing module and is configured to receive the comparison result from the data processing module and control the movement of the light source and/or the outer shell body based on the comparison result so that the relative positions of the light source, the light guide module and the cornea are kept unchanged and incident light is vertically conducted to the eye surface of the patient.
10. The corneal crosslinking system of claim 1, further comprising an alert reminder module, the controller in communication with the alert reminder module and configured to control the alert reminder module to issue an alert reminder based on the positional offset information.
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