CN117695496A - Tinnitus treatment system combining percutaneous pulse stimulation and acoustic treatment - Google Patents
Tinnitus treatment system combining percutaneous pulse stimulation and acoustic treatment Download PDFInfo
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- CN117695496A CN117695496A CN202311717462.0A CN202311717462A CN117695496A CN 117695496 A CN117695496 A CN 117695496A CN 202311717462 A CN202311717462 A CN 202311717462A CN 117695496 A CN117695496 A CN 117695496A
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- 238000011282 treatment Methods 0.000 title claims abstract description 102
- 208000009205 Tinnitus Diseases 0.000 title claims abstract description 62
- 231100000886 tinnitus Toxicity 0.000 title claims abstract description 62
- 230000000638 stimulation Effects 0.000 title claims abstract description 61
- 238000011269 treatment regimen Methods 0.000 claims abstract description 59
- 238000000034 method Methods 0.000 claims abstract description 14
- 150000001875 compounds Chemical class 0.000 claims abstract description 8
- 230000000873 masking effect Effects 0.000 claims abstract description 8
- 238000002560 therapeutic procedure Methods 0.000 claims description 30
- 238000000638 solvent extraction Methods 0.000 claims 1
- 238000000527 sonication Methods 0.000 description 7
- 238000010586 diagram Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 210000001186 vagus nerve Anatomy 0.000 description 2
- 241000931705 Cicada Species 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 241000746998 Tragus Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000001595 mastoid Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000007383 nerve stimulation Effects 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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Abstract
The invention provides a personalized tinnitus treatment system combining percutaneous pulse stimulation and acoustic treatment, which comprises the following components: the system comprises an input module, a music library, a pulse parameter setting module, a treatment strategy generating module and a control module. The input module inputs the patient tinnitus frequency and the treatment strategy instructions ultimately selected by the user. The music library comprises a masking music library, a notch music library and a multi-element compound music library; the music categories of patients meeting different tinnitus frequencies are respectively divided according to a specific dividing method. The pulse parameter setting module sets the pulse parameters in a self-defined mode. The treatment strategy generation module automatically generates three candidate treatment strategies for selection by a user, wherein the candidate treatment strategies for selection by the user comprise acoustic treatment, pulse stimulation treatment and acoustic treatment combined with pulse stimulation treatment. The control module is used for controlling the acoustic treatment and/or the pulse stimulation treatment according to the treatment strategy instruction finally selected by the user. The application provides personalized treatment strategies for different patients according to individual variability.
Description
Technical Field
The invention relates to the technical field of tinnitus treatment, in particular to a method for treating tinnitus by combining pulse electric stimulation and tinnitus sound.
Background
Tinnitus refers to the phenomenon that under the condition that no external sound source exists, the patient perceives disturbing sounds like pure sounds, cicada sounds and the like through subjective hearing, and even insomnia and depression of the patient can be caused, so that normal life of the patient is seriously influenced.
Because the sound treatment is convenient and the treatment cost is low, the device is widely applied to the field of tinnitus treatment, and the specific treatment mode of the sound treatment is to play a proper sound source for a patient so as to achieve the purpose of relieving tinnitus symptoms. Neurological stimulation of the vagus nerve at the ear has been found to be effective in alleviating tinnitus symptoms, with implantable and non-implantable stimulation of the vagus nerve to alleviate tinnitus.
However, the treatment effects are different due to individual differences, and some patients are sensitive to acoustic treatment and have small response to nerve stimulation, so that the acoustic treatment effect is good, and the pulse stimulation nerve therapy effect is poor; patients are relatively insensitive to acoustic treatment and have relatively large response to pulse stimulation; also patients may be better receiving both sonication and pulsed stimulation.
Disclosure of Invention
To overcome the above technical drawbacks, an object of the present invention is to provide a personalized tinnitus treatment system combining percutaneous pulse stimulation with acoustic treatment, comprising:
the input module is used for inputting tinnitus frequency of a patient and inputting a treatment strategy instruction finally selected by a user;
a music library including a masking music library, a notch music library, and a multi-component compound music library; according to different frequency components, the masking music library, the notch music library and the multi-element compound music library are respectively divided into music categories which accord with patients with different tinnitus frequencies according to a specific dividing method;
the pulse parameter setting module is used for setting pulse parameters in a self-defined mode;
a treatment strategy generation module for automatically generating three candidate treatment strategies for user selection, wherein the candidate treatment strategies for user selection comprise acoustic treatment, pulse stimulation treatment and acoustic treatment combined with pulse stimulation treatment;
and the control module is used for controlling the acoustic treatment and/or the pulse stimulation treatment according to the treatment strategy instruction finally selected by the user.
Further, the dividing method comprises equal interval dividing, octave dividing and dividing according to the frequency proportion of the tinnitus patient population.
Further, the pulse parameter is one or more of waveform, frequency, amplitude and signal duty cycle.
Further, the waveform is a square wave, a sine wave, a triangular wave, a trapezoidal wave or a combination of any of the former waveforms.
Further, the frequency is 1-10 kHz.
Further, the amplitude is 0-500 mA.
Further, the signal duty cycle is 0-100%.
Further, the treatment strategy ultimately selected by the user is any one of acoustic treatment, impulse stimulation treatment, acoustic treatment in combination with impulse stimulation treatment.
Further, the acoustic treatment is combined with the pulse stimulation treatment strategy and is divided into an acoustic and pulse arbitrary time alternating treatment strategy, an acoustic and pulse fixed time alternating treatment strategy, an acoustic and pulse arbitrary time random alternating treatment strategy, an acoustic and pulse fixed time random alternating treatment strategy, an acoustic and pulse continuous treatment strategy, an acoustic and pulse arbitrary duty cycle fixed alternating treatment strategy, an acoustic and pulse fixed duty cycle and alternating treatment strategy, an acoustic and pulse arbitrary duty cycle random alternating treatment strategy, and an acoustic and pulse fixed duty cycle random alternating treatment strategy.
Further, the personalized tinnitus treatment system combining transdermal pulse stimulation and acoustic treatment further comprises: the control module is used for controlling the music playing unit and the pulse stimulation unit according to the treatment strategy instruction finally selected by the user.
After the technical scheme is adopted, compared with the prior art, the method has the following beneficial effects:
the personalized tinnitus treatment system combining the percutaneous pulse stimulation and the acoustic treatment provides a method for combining tinnitus acoustic treatment and pulse electric stimulation, and provides several different treatment strategies, and personalized treatment schemes are provided for different patients according to individual differences.
Drawings
FIG. 1 is a block diagram of a personalized tinnitus treatment system of the present application combining transdermal pulse stimulation with acoustic treatment;
FIG. 2 is a flow chart of a personalized tinnitus treatment system of the present application combining transdermal pulse stimulation with acoustic treatment;
FIG. 3 is a schematic diagram of an alternate treatment strategy at any time of sound + pulse;
FIG. 4 is a schematic diagram of an acoustic + pulse random alternating therapy strategy at any time and an acoustic + pulse fixed time random alternating therapy strategy;
FIG. 5 is a schematic diagram of an acoustic + pulse duration treatment strategy;
FIG. 6 is a schematic diagram of an alternate treatment strategy with arbitrary duty cycle fixed with sound + pulses and alternate treatment with fixed duty cycle of sound + pulses;
fig. 7 is a schematic diagram of an acoustic + pulse random duty cycle random alternating therapy strategy and an acoustic + pulse fixed duty cycle random alternating therapy strategy.
Detailed Description
Advantages of the invention are further illustrated in the following description, taken in conjunction with the accompanying drawings and detailed description. It is to be understood by persons skilled in the art that the following detailed description is illustrative and not restrictive, and that this invention is not limited to the details given herein.
As shown in fig. 1, the present embodiment provides a personalized tinnitus treatment system combining transdermal pulse stimulation with acoustic treatment, comprising: the device comprises an input module, a music library, a pulse parameter setting module, a treatment strategy generating module, a control module, a music playing unit and a pulse stimulating unit.
The input module is used for inputting tinnitus frequency of a patient and inputting treatment strategy instructions finally selected by a user.
The music library comprises a masking music library, a notch music library and a multi-element compound music library; according to different frequency components, the masking music library, the notch music library and the multi-component compound music library are respectively divided into music categories which accord with patients with different tinnitus frequencies according to a specific dividing method.
The pulse parameter setting module is used for setting pulse parameters in a self-defined mode.
The treatment strategy generation module is used for automatically generating three candidate treatment strategies for user selection, wherein the candidate treatment strategies for user selection comprise acoustic treatment, pulse stimulation treatment and acoustic treatment combined with pulse stimulation treatment.
The control module is used for controlling the music playing unit and the pulse stimulation unit according to the treatment strategy instruction finally selected by the user.
As shown in fig. 2, the practical application method for performing the personalized tinnitus treatment by adopting the personalized tinnitus treatment system combining the percutaneous pulse stimulation and the acoustic treatment comprises the following steps:
1. early preparation work
1. Testing tinnitus frequency of patient
The method comprises the steps of playing a plurality of pure tones with different known frequencies for a tinnitus patient in advance, judging whether the pure tones are close to the tinnitus sound of the patient by the patient, and finding the frequency corresponding to the close pure tones to obtain the tinnitus frequency of the patient.
2. Construction of a library of sound therapy music
(1) The method is divided into masking sound, notch music and multi-element compound sound according to the acoustic treatment method;
(2) The three different pieces of sound treatment music are divided into categories which accord with different tinnitus frequency patients according to different frequency components, wherein the dividing modes comprise, but are not limited to, equal interval dividing, octave dividing and frequency proportion dividing according to the tinnitus patient population.
3. Setting pulse parameters
The patient may also customize the stimulation parameters in the pulse parameter setting module, including but not limited to the following:
(1) Waveform: including but not limited to square waves, sine waves, triangular waves, trapezoidal waves, etc., or a combination of any of the foregoing;
(2) Frequency: combinations or permutations of ranges between 1 to 10kHz, such as 1 to 100Hz,150 to 500Hz,500 to 1000Hz,1000 to 10kHz, or any of the foregoing;
(3) Duty cycle: may be between 0 and 100%, for example 1%, 5%, 10%, 15% to 99.9%, or a combination or permutation of any of the foregoing;
(4) Amplitude: the range may be between 0 and 500mA, for example 0 to 12mA, 0 to 100mA, 0 to 200mA, 0 to 500mA, and the gear step may be between 0.1 and 10 mA.
2. Personalized tinnitus treatment using the personalized tinnitus treatment system of the present application
1. User input of patient tinnitus frequency
And judging the tinnitus frequency of the patient according to the method, and inputting the tinnitus frequency of the patient into the personalized tinnitus treatment system through an input module.
2. Automated generation of three candidate treatment strategies
The treatment strategy generation module automatically generating three candidate treatment strategies for selection by a user comprises:
(1) Acoustic treatment: selecting matched music in a music library to play according to tinnitus frequency of a patient; the personalized tinnitus treatment system acquires tinnitus frequency f of a patient, and the treatment strategy generation module recommends treatment sound sources matched in three treatment modes for the patient each time according to the tinnitus frequency f, wherein the matched modes need to contain the tinnitus frequency f of the patient according to the corresponding music frequency distribution.
(2) Pulse stimulation treatment: the ear of the patient is stimulated according to the patient custom parameters.
(3) Acoustic therapy + impulse stimulation therapy (illustrated by square waves but not limited to the combination of therapeutic sound and the waveform):
(3.1) Sound + pulse alternate treatment at any time: as shown in fig. 3, the duration t of sonication in this mode 1 And pulse duration t 2 Is a non-fixed value that varies arbitrarily.
(3.2) Sound+pulse fixed time alternating treatment: reference is also made toFIG. 3 duration t of sonication in this mode 1 And pulse duration t 2 Is fixed.
(3.3) sound + pulse randomly alternating treatment at any time: as shown in fig. 4, the duration t of sonication in this mode 1 And pulse duration t 2 Is a non-fixed value that varies arbitrarily and the sonications and pulses alternate randomly.
(3.4) sound + pulse fixed time random alternating treatment: also shown in fig. 4, the duration t of sonication in this mode 1 And pulse duration t 2 Is a fixed value and the sonications and pulses are randomly alternating.
(3.5) sound + pulse duration treatment: referring to fig. 5, the acoustic therapy and the pulse stimulation therapy are continued for the entire treatment time t in this mode.
(3.6) Sound+pulse arbitrary duty cycle fixed alternating therapy:
referring to fig. 6, the acoustic therapy and the pulsed stimulation therapy coincide at any time t throughout the therapy in this mode, while the alternation of acoustic and pulses occurs fixedly.
(3.7) Sound+pulse fixed duty cycle and alternate treatment: referring to fig. 6, the acoustic therapy and the pulsed stimulation therapy coincide at a fixed time t throughout the therapy in this mode, with a fixed occurrence of alternation of acoustic and pulses.
(3.8) sound + pulse arbitrary duty cycle random alternating treatment: referring to fig. 7, the acoustic therapy and the pulsed stimulation therapy coincide at any time t throughout the therapy in this mode, with random alternations of acoustic and pulses.
(3.9) fixed-duty-cycle random alternating treatment of sound + pulses: referring to fig. 7, the acoustic therapy and the pulsed stimulation therapy overlap at a fixed time t throughout the therapy in this mode, with random alternations of the acoustic and pulse.
3. The user selects one of the treatment strategies
The patient selects one of the recommended three treatment strategies based on personal preferences.
4. Executing a user selected tinnitus treatment strategy
The execution unit of the tinnitus treatment strategy comprises a music playing unit and a pulse stimulation unit, and the specific structures of the music playing unit and the pulse stimulation unit are not limited, and any structure capable of realizing the music playing function and the pulse stimulation function can be adopted. The personalized tinnitus treatment system receives the treatment strategy instruction selected by the user, and the control module controls the music playing unit and/or the pulse stimulation unit to carry out tinnitus treatment according to the treatment strategy instruction selected by the user. For example, the time of the acoustic treatment and the pulse stimulation treatment may be controlled for any of 0 to 60 minutes, 1h, 2h, 3h, 4h, 5h, 6h, 7h, 8h, 9h, 10h, 11h, 12h, 13h, 14h, 15h, 16h, 17h, 18h, 19h, 20h, 21h, 22h, 23h, 24 h.
The pulse stimulation output by the pulse stimulation unit is to release micro-current to stimulate the ears of the patient. The stimulation sites include, but are not limited to, the concha, concha cavity, tragus, nebula, mastoid cavity, hilum, auditory womb, auditory station, etc., and/or acupoints.
The music playing unit plays the matched therapeutic sound source selected by the user, and the matching mode is to contain tinnitus frequencies of patients according to the distribution of the corresponding music frequencies.
It should be noted that the embodiments of the present invention are preferred and not limited in any way, and any person skilled in the art may make use of the above-disclosed technical content to change or modify the same into equivalent effective embodiments without departing from the technical scope of the present invention, and any modification or equivalent change and modification of the above-described embodiments according to the technical substance of the present invention still falls within the scope of the technical scope of the present invention.
Claims (10)
1. A personalized tinnitus treatment system combining transdermal pulse stimulation with sound therapy comprising:
the input module is used for inputting tinnitus frequency of a patient and inputting a treatment strategy instruction finally selected by a user;
a music library including a masking music library, a notch music library, and a multi-component compound music library; according to different frequency components, the masking music library, the notch music library and the multi-element compound music library are respectively divided into music categories which accord with patients with different tinnitus frequencies according to a specific dividing method;
the pulse parameter setting module is used for setting pulse parameters in a self-defined mode;
a treatment strategy generation module for automatically generating three candidate treatment strategies for user selection, wherein the candidate treatment strategies for user selection comprise acoustic treatment, pulse stimulation treatment and acoustic treatment combined with pulse stimulation treatment;
and the control module is used for controlling the acoustic treatment and/or the pulse stimulation treatment according to the treatment strategy instruction finally selected by the user.
2. The personalized tinnitus treatment system of claim 1 in combination with transdermal pulse stimulation and acoustic treatment wherein the partitioning method comprises equally spaced, octave, frequency-based division according to tinnitus patient population frequency ratio.
3. The personalized tinnitus treatment system in combination with sound therapy of claim 1 wherein the pulse parameters are one or more of waveform, frequency, amplitude, signal duty cycle.
4. A personalized tinnitus treatment system combining transdermal pulse stimulation with sound therapy according to claim 3, wherein the waveform is a square wave, sine wave, triangular wave, trapezoidal wave or a combination of any of the foregoing.
5. A personalized tinnitus treatment system combining transdermal pulse stimulation with sound therapy according to claim 3, wherein the frequency is 1-10 kHz.
6. A personalized tinnitus treatment system combining transdermal pulse stimulation with sound therapy according to claim 3, wherein the amplitude is 0-500 mA.
7. A personalized tinnitus treatment system combining transdermal pulse stimulation with sound therapy according to claim 3 wherein the signal duty cycle is 0-100%.
8. The transdermal pulse stimulation and acoustic treatment combined personalized tinnitus treatment system of claim 1, wherein the user's final selected treatment strategy is any one of acoustic treatment, pulse stimulation treatment, acoustic treatment combined pulse stimulation treatment.
9. The transdermal pulse stimulation and acoustic treatment combined personalized tinnitus treatment system of claim 1, wherein the acoustic treatment combined pulse stimulation treatment strategy is divided into an acoustic and pulse arbitrary time alternating treatment strategy, an acoustic and pulse fixed time alternating treatment strategy, an acoustic and pulse continuous treatment strategy, an acoustic and pulse arbitrary duty cycle fixed alternating treatment strategy, an acoustic and pulse fixed duty cycle and alternating treatment strategy, an acoustic and pulse arbitrary duty cycle random alternating treatment strategy, an acoustic and pulse fixed duty cycle random alternating treatment strategy.
10. A personalized tinnitus treatment system according to any one of claims 1-9 in combination with sound therapy further comprising: the control module is used for controlling the music playing unit and the pulse stimulation unit according to the treatment strategy instruction finally selected by the user.
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| CN202311717462.0A CN117695496A (en) | 2023-12-13 | 2023-12-13 | Tinnitus treatment system combining percutaneous pulse stimulation and acoustic treatment |
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| CN202311717462.0A CN117695496A (en) | 2023-12-13 | 2023-12-13 | Tinnitus treatment system combining percutaneous pulse stimulation and acoustic treatment |
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