CN117693294A

CN117693294A - Composition for controlling arthropods

Info

Publication number: CN117693294A
Application number: CN202280049254.5A
Authority: CN
Inventors: 乔纳森·哈维尔·卡尔德拉斯; 迈克尔·D·缪
Original assignee: Procter and Gamble Co
Current assignee: Procter and Gamble Co
Priority date: 2021-07-23
Filing date: 2022-07-22
Publication date: 2024-03-12

Abstract

The present disclosure relates to insecticidal compositions and methods of controlling pests (such as insects and other arthropods). More particularly, the present disclosure relates to an insecticidal composition that leaves less residue on treated surfaces while providing effective control of arthropods.

Description

Composition for controlling arthropods

Technical Field

Background

Insects and other arthropod pests can negatively impact the quality of human life. For example, when insects and other arthropods are found in the home, their presence can be a source of annoyance. They can also transmit diseases and allergens. For example, domestic cockroaches produce allergens in their saliva, which can cause problems for allergic patients. It is also desirable to control other crawling arthropods such as ants, beetles, earwigs, silverfish, crickets, spiders, centipedes and various flying insects including flies, mosquitoes, gnats, moths, wasps, hornet, bees, and the like.

There are currently a variety of arthropod pest control products to control various arthropod pests such as cockroaches, ants, flies and gnats, both indoors and outdoors. Also, the market for arthropod pest control products is growing due to factors such as an increase in urban houses, an increase in consumer awareness of health and hygiene, and a change in weather patterns. Meanwhile, there is an increasing demand for more renewable or more natural arthropod pest control products by consumers. Consumers also prefer pest control products that contain a limited number of ingredients and/or identifiable ingredients, as conveyed by the simpler description of the ingredients. However, these products are still expected to be effective and effective against arthropod pests as compared with conventional pest control products.

Existing arthropod pest control products contain natural ingredients such as plant essential oils. However, these existing products have a number of disadvantages: some products may be messy to use and/or may leave residues on the treated surface; some products may be unstable or separate into multiple phases at low temperatures (i.e., about 5 ℃ to 10 ℃) and require the user to shake the product vigorously before use; some products are not recommended for food contact surfaces and some have limited efficacy. Other products do not provide an optimal scent experience, such as emitting a persistent, unpleasant scent. Some consumers prefer clear products over cloudy or cloudy (i.e., higher turbidity) products. Accordingly, there is a need for effective arthropod pest control compositions comprising fewer and/or natural ingredients, which are less messy to use (e.g., reduced residues), which can be used on food contact surfaces, which provide improved aesthetics, and/or which provide an improved odor experience.

Disclosure of Invention

An insecticidal composition, the insecticidal composition comprising:

a. from about 40% to about 95% water by weight of the composition;

b. from about 0.01% to about 15%, by weight of the composition, of potassium oleate;

c. from about 1% to about 45% isopropyl alcohol by weight of the composition;

d. optionally, from about 0.01% to about 15% sodium bicarbonate by weight of the composition; and

e. optionally, from about 0.01% to about 1%, by weight of the composition, of anhydrous citric acid, citric acid monohydrate, or a combination thereof;

f. from about 1% to about 15%, by weight of the composition, of one or more active ingredients selected from the group consisting of: corn mint oil, peppermint oil, spearmint oil, rosemary oil, thyme oil, citronella oil, clove oil, cedar oil, cinnamon oil, geranium oil, eugenol, 2-phenylethyl propionate, menthol, menthone, thymol, carvone, camphor, methyl salicylate, p-isopropyl toluene, linalool, geraniol, lauryl acetate, cinnamyl alcohol, cinnamaldehyde, citronellol, eucalyptol/1, 8-eucalyptol, alpha-pinene, borneol acetate, gamma-terpinene, and combinations thereof;

Wherein the composition has a pH of about 4.5 to about 11.0.

Detailed Description

Consumers are looking for effective and natural methods to control a variety of arthropods. However, existing arthropod pest control products containing natural ingredients often are messy, unstable, and/or present an unpleasant consumer experience, such as requiring the consumer to shake the product and/or look color before use. Described herein are aqueous pesticidal compositions that are substantially clear, substantially colorless, and stable (preferably without shaking prior to use), and are effective against arthropod pests. As used herein, "stable" refers to a substantially clear and phase separation or precipitation free insecticidal composition, wherein the insecticidal composition is used without agitation or mixing for its application. The aqueous insecticidal compositions described herein are less messy to use, are easy to clean, and have acceptable product odor, aesthetics, or other characteristics, such as being useful on food contact surfaces.

The features and advantages of the various embodiments of the present invention will become apparent from the following description, which includes examples intended to give a broad representation of the specific embodiments of the invention. Various modifications will be apparent to those skilled in the art from this description and from the practice of the invention. It is not intended to be limited to the specific forms disclosed, and the invention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the invention as defined by the claims.

As used herein, articles such as "a" and "an" when used in the claims are understood to mean one or more of the substance being protected or described by the claims.

As used herein, the terms "comprising," "including," and "containing" are intended to be non-limiting.

The term "renewable" is synonymous with the terms "natural", "bio-derived", "biobased" and means that the material originates from a substance derived from a living organism (e.g. a farmed plant) rather than, for example, a substance derived geologically (e.g. coal derived or petroleum derived).

"geologically derived" means derived from, for example, petrochemical products, natural gas, or coal. "geologically derived" materials cannot be readily replenished or regrown (e.g., as opposed to plant or algae-produced materials).

As used herein, the term "renewable component" refers to a component derived from a renewable feedstock and comprising renewable carbon. Renewable feedstocks are feedstocks that are derived from renewable sources (e.g., plants) and are not geologically derived. The material may be partially renewable (less than 100% renewable carbon content, about 1% to about 90% renewable carbon content, or about 1% to about 80% renewable carbon content, or about 1% to about 60% renewable carbon content, or about 1% to about 50% renewable carbon content) or 100% renewable (100% renewable carbon content). The renewable feedstock may be mixed or chemically reacted with the geology-derived feedstock to produce a material having renewable components and geology-derived components.

The "renewable carbon" can be evaluated using the "biobased content evaluation of materials" method ASTM D6866-16.

As used herein, the term "natural oil" refers to an oil (also referred to as a renewable oil) derived from plant or algae matter. Natural oils are not based on kerosene or other fossil fuels. The term "oil" includes fats, fatty acids, waste fats, oils or mixtures thereof. Natural oils typically include triglycerides, free fatty acids or a combination of triglycerides and free fatty acids, as well as other trace compounds.

As used herein, the term "substantially free" or "substantially free" refers to a component that is completely absent or is only present as a minimal amount of impurities or unintended by-products of another component. By "substantially free/free" of components, it is meant that the composition comprises less than about 0.5%, less than about 0.25%, less than about 0.1%, less than about 0.05%, or even less than about 0.01% of components by weight of the composition.

The term "dye" as used herein includes aesthetic dyes that alter the aesthetic appearance of an arthropod pest control composition. Dyes include colorants and pigments.

Volatile Organic Compounds (VOCs) are defined by the United states Environmental Protection Agency (EPA) as organic compounds that participate in atmospheric photochemical reactions, except for compounds that have negligible photochemical reactivity. VOCs are typically discharged in gaseous form from certain solids or liquids. The insecticide may be formulated to contain 40% or less VOC by weight. The VOC level may be about 1wt.% to about 35wt.%, or about 2wt.% to about 20wt.%.

Unless otherwise indicated, all component or composition levels are in terms of the active portion of the component or composition and do not include impurities, such as residual solvents or byproducts, that may be present in commercially available sources of such components or compositions.

All percentages and ratios are by weight unless otherwise indicated. All percentages and ratios are calculated based on the total composition unless otherwise indicated. It is to be understood that each maximum numerical limit set forth throughout this specification includes each lower numerical limit as if such lower numerical limit were explicitly written herein. Every minimum numerical limitation given throughout this specification will include every higher numerical limitation, as if such higher numerical limitations were expressly written herein. Every numerical range given throughout this specification will include every narrower numerical range that falls within such broader numerical range, as if such narrower numerical ranges were all expressly written herein.

Arthropod pest control composition

The arthropod pest control composition is preferably in liquid form. The arthropod pest control composition is preferably an aqueous composition. The aqueous liquid compositions are convenient to use because these compositions can be easily applied directly to arthropod pests without leaving residues on adjacent surfaces. The arthropod pest control composition may comprise from about 40% to about 95%, preferably from about 50% to about 90%, or from about 55% to about 80%, or from about 58% to about 78%, or from about 60% to about 75%, or from about 62% to about 72% water by total weight of the composition. The arthropod pest control composition may be clear, as clear means pure to the user. The arthropod pest control composition may be provided in the form of a ready-to-use composition that can be applied directly to the arthropod pest (e.g., as a spray) and does not require dilution by the consumer prior to use. The ready-to-use composition may be preferred by some consumers because the ready-to-use composition does not require dilution by the consumer, which may be confusing, inconvenient and/or require multiple containers. The arthropod pest control compositions disclosed herein can contain selected amounts of selected ingredients suitable for direct spraying onto the arthropod pests.

The arthropod pest control compositions disclosed herein may be substantially free of geologically derived (e.g., petroleum-based) oils, such as mineral oils, because products containing mineral oils may be messed to use and may leave residues on the treated surface.

The pH of the arthropod pest control composition may be from about 4.5 to about 11.0, preferably from about 7.0 to about 9.0, more preferably from about 7.5 to about 8.5. The pH of the composition may be adjusted using pH adjusting ingredients known in the art.

The arthropod pest control compositions disclosed herein can have a relatively high level of clarity (i.e., low turbidity). Some consumers prefer clear products over cloudy or dirty (i.e., higher turbidity) products. The composition may exhibit a turbidity of less than about 20NTU, preferably less than about 5NTU, and greater than or equal to about 0 NTU. The composition may exhibit a turbidity of about 1 to about 10 NTU. As described in the test methods section below, the turbidity of the composition was measured with a laboratory turbidimeter.

The arthropod pest control compositions disclosed herein can have reduced yellow color. Some consumers prefer colorless or substantially colorless products over yellow products. Yellow may be a characteristic of the breakdown of certain active ingredients in the composition, particularly vegetable oils (such as corn mint oil and rosemary oil). The reduction in yellow color may be measured by any colorimetry or spectroscopy method known in the art. Suitable colorimetric methods include, for example, the Gardner color scale (according to the American Society for Testing and Materials ("ASTM") method ASTM D1544, D6166 and/or American Oil Chemists' Society ("AOCS") method AOCS Td-1 a-64); CIELAB color code (according to ASTM D5386-93 b); the American Public Health Association ("APHA") color scale (according to ASTM D1209 or AOCS Td-1 b-64); saybolt color scale (according to ASTM D156 or D6045); lovibond (red) scale (according to AOCS Cc-13 b-45). The CIELAB color scale can be used to quantify the color of an arthropod pest control composition. The CIELAB color scale may also be referred to as L x a x b x, which is a color scale defined by the international commission on illumination (abbreviated CIE) in 1976. The CIELAB color scale represents color as three values: l denotes perceived brightness, a and b denote four distinct colors of human vision (red, green, blue and yellow), where the b value represents blue/yellow. It should be noted that the present disclosure is not limited to any particular colorimetric measurement, and that the observed reduction in yellow may be measured by any suitable colorimetric method.

The arthropod pest control composition of the present disclosure may contain renewable components and exhibit good efficacy against arthropod pests. The compositions disclosed herein may comprise from about 1%, or about 5%, or about 10%, or about 20%, or about 30%, or about 40%, or about 50% to about 40%, or to about 50%, or to about 60%, or to about 70%, or to about 80%, or to about 90%, or to about 100% by weight of renewable components. The compositions disclosed herein may be at least partially or completely bio-based. Thus, the composition may comprise a biobased carbon content of from about 50% to about 100%, preferably from about 70% to about 100%, more preferably from about 75% to about 100%, even more preferably from about 80% to about 100%, most preferably from about 90% to about 100%. The biobased carbon content percentage may be calculated as "modern carbon percentage (pMC)" derived using the methodology of ASTM D6866-16. The compositions of the present disclosure may be substantially free of petroleum derived solvents or petroleum derived surfactants.

The compositions disclosed herein may comprise less than about 15 ingredients, preferably less than about 10 ingredients, more preferably less than about 15 ingredients and more than about 5 ingredients.

The compositions disclosed herein may comprise the ingredients listed in federal pesticide, bactericide and rodenticide act (Federal Insecticide, fungicide, and Rodenticide Act, FIFTRA) section 25 (b), which is incorporated herein by reference in its entirety. The compositions disclosed herein may comprise naturally occurring compounds or extracts or derivatives thereof. The compositions disclosed herein may comprise at least one organic, certified organic, ingredient conforming to the united states department of agriculture ("USDA") national organic program ("NOP-compliance"). The compositions disclosed herein may comprise at least one food grade or generally recognized safety (GRAS) ingredient. GRAS ingredients may include any of the agents listed on the FDA's GRAS list, including direct Food additives (see, e.g., section 201(s) and 409 of the US law (Federal Food, drug, and Cosmetic Act), the GRAS ingredients may also include, but are not limited to, substances commonly approved by professionals with scientific training and experience in assessing their safety, which have been fully proven safe by scientific procedures (or for substances used in foods prior to 1 month 1 of 1958, by scientific procedures or based on experience commonly used in foods).

Active ingredient

The arthropod pest control composition may comprise one or more active ingredients (also referred to herein as actives). The arthropod pest control composition may comprise from about 0.005% to about 15%, or from about 0.05% to about 12%, or from about 0.5% to about 10%, or from about 1% to about 7%, or from about 1.00% to about 15%, of one or more active ingredients of the composition.

Non-limiting examples of active ingredients include aldehyde C16 (pure), almond oil, terpene, alpha-terpineol, verbenone, alpha-cedrene, cinnamaldehyde, amyl cinnamaldehyde, lauryl acetate, amyl salicylate, anisaldehyde, citric acid, cedrol, benzyl alcohol, benzyl acetate, cinnamaldehyde, cinnamyl alcohol, carvacrol, caryophyllene, and combinations thereof carveol, citral, citronellal, methylheptenone (methylhepenone), citronellol (citronellol), dimethyl salicylate, eucalyptol (also known as 1, 8-cineole), thujacene (thujone), 3-thujanone (3-thujosan), alpha-thujanone (alpha-thujone), beta-thujanone (beta-thujone), fenchone (fenchone) eugenol acetate (e.g., isoeugenol acetate), eugenol, isoeugenol methyl ether, jiale musk (glaxolide), geraniol, guaadiene (guaiaadene), guaiacol (guaiacol), ionone, menthol (e.g., L-menthol), menthyl ester, menthone, carvone (e.g., L-carvone), camphor, camphene (camphene), p-isopropyl toluene, borneol esters (born esters), borneol acetate, isobornyl acetate, terpinene (e.g., gamma-terpinene), methyl anthranilate (methyl anthranilate), methyl ionone, methyl salicylate, nerol, phellandrene (e.g., alpha-phellandrene), peppermint oil, perillaldehyde, 1-or 2-phenylethanol, phellandrene, phenyl ethyl 1-or 2-propionate, piperonal, piperonyl acetate, piperonyl alcohol, pulegone (D-pulegone), 4-terpineol (terpinen-4-ol), terpinyl acetate (terpinyl acetate), 4-tert-butylcyclohexyl acetate, myrcene, niclosan (chavicol), acetaldehyde, safrole, 4-terpineol, eucalyptol, dimethyl trisulfide, diallyl disulfide, diallyl sulfide, diallyl tetrasulfide, 3-vinyl-4H-1, 2-dithiin (3-vinyl- [4H ] -1, 2-dithiin), thyme oil (white), thyme oil (red), thymol, anethole (e.g. trans-anethole), vanillin, ethyl vanillin, castor oil, cedar oil (cedar oil) cedar wood oil (cedarwood oil), cinnamon oil, citronella oil, clove oil, corn mint oil (corn mint oil), oregano oil, cotton seed oil garlic, garlic oil, geranium oil, lemon grass oil, linseed oil, peppermint oil, spearmint oil, rose oil, spearmint oil, peppermint oil peppermint, peppermint oil spea, peppermint oil spearmint oil, peppermint rosemary, rosemary oil, sesame oil, soybean oil, white pepper, licorice oil, wintergreen oil, fennel oil (e.g., star anise oil), clove flower oil, black seed oil, bay oil (bay oil), grapefruit seed oil, grapefruit, lemon oil, orange flower oil, tea tree oil, cedar leaf oil, camphor oil, marigold (tagetes minuta) oil, lavender oil, lippia javanica oil, bergamot oil (galbanum oil), eucalyptus oil, angelicae pubescens oil, and mixtures thereof.

The arthropod pest control composition may comprise one or more active ingredients selected from the group consisting of: plant essential oils (including synthetic analogs), eugenol, 2-phenylethyl propionate, amyl butyrate, geraniol, limonene (e.g., d-limonene), linalool, methyl salicylate, pinene (e.g., α -pinene, β -pinene), piperonal, piperonyl alcohol, tetrahydrolinalool, thymol, vanillin, ethyl vanillin, isoeugenol, ethyl cinnamate, pyrethrin, abamectin, azadirachtin, amitraz, rotenone, boric acid, spinosad, biopesticides, synthetic insecticides, and mixtures thereof.

The arthropod pest control composition may comprise an active ingredient selected from the group consisting of: eugenol, 2-phenylethyl propionate, menthol, menthone, thymol, carvone (e.g., L-carvone), camphor, methyl salicylate, p-isopropyl toluene, linalool, linalyl acetate, eucalyptol, alpha-pinene, borneol acetate, isobornyl acetate, gamma-terpinene, lauryl acetate, cinnamyl alcohol, cinnamaldehyde, and combinations thereof. The arthropod pest control composition may comprise a plant essential oil, such as corn mint oil, peppermint oil, spearmint oil, rosemary oil, thyme oil, citronella oil, clove oil, and cedar wood oil.

The arthropod pest control composition may comprise from about 0.005% to about 15%, from about 0.05% to about 12%, from about 0.5% to about 10%, from about 1% to about 7%, from about 1% to about 15%, by weight of the composition, of one or more active ingredients, wherein the active ingredient is a plant essential oil. The arthropod pest control composition may comprise one or more plant essential oils selected from the group consisting of: corn mint oil, peppermint oil, spearmint oil, rosemary oil, thyme oil, citronella oil, clove oil, cedar wood oil, and mixtures thereof, preferably selected from corn mint oil, spearmint oil, rosemary oil, thyme oil, and mixtures thereof, more preferably selected from corn mint oil, rosemary oil, and combinations thereof.

The arthropod pest control composition described herein may comprise from about 0.01% to about 1%, preferably from about 0.01% to about 0.8%, more preferably from about 0.01% to about 0.6% citric acid or a salt thereof, preferably anhydrous citric acid or citric acid monohydrate, by weight of the composition. The compositions described herein may comprise from about 0.01% to about 1% by weight of the composition of citric acid or a salt thereof, such as potassium citrate, monopotassium citrate, tripotassium citrate monohydrate, or dipotassium citrate. Citric acid may also function to adjust the pH of the composition and/or as a chelating agent.

The arthropod pest control composition may comprise one or more synthetic pesticides. Non-limiting examples of synthetic insecticides include pyrethroids such as bifenthrin, fenvalerate, fenpropathrin, permethrin, fenvalerate, cyfluthrin, deltamethrin, allethrin, lambda-cyhalothrin, and the like; synthetic agents such as piperonyl butoxide and the like; juvenile hormone analogs such as methoprene, hydroprene, methoprene, and the like; and neonicotinoids such as imidacloprid, acetamiprid, thiamethoxam, and the like, and mixtures thereof. The arthropod pest control composition may comprise less than about 10%, or less than about 5%, or less than about 2%, or less than about 1%, or less than about 0.5% by weight of synthetic pesticide. Alternatively, the arthropod pest control composition may be substantially free of synthetic pesticides.

The arthropod pest control composition may comprise one or more biopesticides. Non-limiting examples of biopesticides include pyrethrum, rotenone, neem oil, and mixtures thereof.

Fatty acid/fatty acid salts (soaps)

The arthropod pest control compositions disclosed herein may be formulated with one or more fatty acids or salts thereof. The pest control composition comprises from about 0.01% to about 15%, or from about 0.1% to about 10%, or from about 1% to about 5% of one or more fatty acids or salts thereof.

The spray droplets of the pesticidal composition comprising the active agent are preferably capable of wetting the target surface and spreading or covering the target area to perform its intended function. Fatty acids or salts thereof typically reduce the surface tension of water on the surface of the spray droplets by reducing the interfacial tension between the spray droplets and the target surface (e.g., the exoskeleton of an arthropod). The fatty acid or salt thereof also wets and disperses the particles of the active ingredient in the composition prior to spraying, thereby enabling more uniform coverage and wetting of the target arthropod upon spraying. The fatty acid or salt thereof may also function to emulsify an active agent that is not readily soluble in water (e.g., an oil).

Fatty acids and salts thereof are organic molecules comprising a single carboxylic acid moiety (carboxylate anion in the salt) and at least 7 carbon atoms, or about 11 to about 22 carbon atoms, or about 12 to about 16 carbon atoms. Fatty acids or salts thereof are considered anionic surfactants containing long-chain hydrocarbon hydrophobic groups and hydrophilic groups, i.e., carboxylic acid/carboxylate, in their molecular structure. These salts may be sodium, potassium, calcium, magnesium, barium, iron, ammonium and amine salts of fatty acids. Salts of fatty acids are also known as soaps. The fatty acids and salts thereof may be linear, branched, saturated, unsaturated, cyclic or mixtures thereof. Non-limiting examples of fatty acids and salts thereof include lauric acid, myristic acid, palmitic acid, stearic acid, arachic acid, behenic acid, lignoceric acid, myristoleic acid, palmitoleic acid, palmitic acid, oleic acid, elaidic acid, iso-oleic acid, linoleic acid, linolenic acid, arachidonic acid, eicosapentaenoic acid, erucic acid, docosahexaenoic acid, sodium, calcium, potassium or zinc salts thereof, or mixtures thereof. Preferred fatty acid soaps are alkali metal salts of oleic acid, preferably sodium or potassium oleate, more preferably sodium oleate. The arthropod pest control composition may comprise from about 0.01% to about 15%, or from about 0.1% to about 10%, or from about 1% to about 5% by weight of fatty acids or salts thereof. The arthropod pest control composition may comprise from about 0.01% to 15%, or from about 0.1% to about 10%, or from about 1% to about 5%, by weight of the composition, of potassium oleate.

Additional surfactant

The arthropod pest control composition of the present disclosure may comprise an additional anionic surfactant and/or one or more surfactants selected from the group consisting of: amphoteric surfactants, zwitterionic surfactants, nonionic surfactants, cationic surfactants, and mixtures thereof. Suitable additional anionic surfactants include alkyl sulfates and alkali metal salts thereof (e.g., sodium dodecyl/lauryl sulfate). Alternatively, the arthropod pest control composition may be substantially free of sodium lauryl sulfate.

Solvent(s)

The arthropod pest control compositions described herein may comprise from about 1% to about 45%, or from about 1% to about 30%, or from about 1% to about 25%, or from about 1% to about 15%, by weight of the composition, of one or more solvents. The liquid arthropod pest control composition may comprise one or more solvents and water.

Suitable solvents include alcohols, such as monohydric or polyhydric alcohols. Preferred alcohols are the low molecular weight primary or secondary alcohols exemplified by ethanol, propanol and isopropanol, with isopropanol being preferred. Monohydric and polyhydric alcohols, such as those containing from 2 to about 6 carbon atoms and from 2 to about 6 hydroxyl groups (e.g., ethylene glycol, glycerol, and 1, 2-propanediol (also known as propylene glycol)), may also be used.

Suitable solvents also include esters. The arthropod pest control composition may comprise from about 0.005% to about 15%, or from about 0.05% to about 12%, or from about 0.5% to about 10%, or from about 1% to about 7%, by weight of the composition, of one or more esters. Esters are typically formed by reacting a carboxylic acid with a molecule containing one or more hydroxyl groups. Examples of suitable carboxylic acids include acetic acid, formic acid, lactic acid, citric acid, malic acid, oxalic acid, propionic acid, propynylic acid, butyric acid, isobutyric acid, caproic acid, adipic acid, benzoic acid, salicylic acid, caprylic acid, and fatty acids. Non-limiting examples of molecules containing one or more hydroxyl groups include methanol, ethanol, sorbitol, propanol, isopropanol, butanol, sec-butanol, isobutanol, tert-butanol, ethylene glycol, propylene glycol, glycerol, polyglycerol, cyclohexanol, and benzyl alcohol. Examples of suitable esters include isopropyl myristate, tetradecyl myristate, isopropyl palmitate, octyl palmitate, isopropyl isothermal (isopropyl isothermal), butyl lactate, ethyl lactate, butyl stearate, triethyl citrate, glycerol monooleate, glycerol dioctanoate, glycerol dimyristate, glycerol dioleate, glycerol distearate, glycerol monostearate, glycerol monocaprylate, glycerol monooleate, glycerol monostearate, decyl oleate, glycerol stearate, octyl stearate, putty stearate, isostearyl pivalate, PPG myristyl propionate, diglycerol monooleate, and diglycerol monostearate. The arthropod pest control composition may comprise ethyl lactate, preferably from about 0.005% to about 15%, or from about 0.05% to about 12%, or from about 0.5% to about 10%, or from about 1% to about 7%, by weight of the composition.

Additional solvents include lipophilic fluids including silicones, other silicones, hydrocarbons, glycol ethers, glycerol derivatives (such as glycerol ethers), perfluorinated amines, perfluorinated and hydrofluoroether solvents, low-volatility nonfluorinated organic solvents, glycol solvents, and mixtures thereof.

Suitable solvents listed in section 25 (b) of the federal pesticide, fungicide and rodenticide act (FIFTRA) include butyl lactate (including its enantiomers), vinegar, 1, 2-propanediol carbonate, isopropyl myristate, ethyl lactate (including its enantiomers) and glycerol.

Preferred solvents include isopropanol, ethanol, glycerol, ethyl lactate, renewable forms thereof, and mixtures thereof. The arthropod pest control composition described herein may comprise from about 1% to about 45%, or from about 1% to about 30%, or from about 1% to about 25%, or from about 1% to about 15%, by weight of the composition, of a solvent selected from the group consisting of: isopropyl alcohol, glycerol, ethyl lactate, and mixtures thereof.

Bicarbonate salt

The arthropod pest control composition may comprise bicarbonate, preferably a bicarbonate inorganic salt, more preferably sodium bicarbonate. The arthropod pest control composition may comprise from about 0.01% to about 15%, preferably from about 0.1% to about 8%, more preferably from about 0.4% to about 4%, by weight of the composition, of bicarbonate, preferably sodium bicarbonate.

Polysaccharide gum

The arthropod pest control compositions disclosed herein can comprise a polysaccharide gum. Suitable polysaccharide gums include xanthan gum, guar gum, acacia gum, cellulose and cellulose derivatives. The arthropod pest control composition disclosed herein can comprise xanthan gum.

The arthropod pest control composition of the present disclosure may comprise from about 0.1% to about 7.5%, or from about 0.5% to about 4.5%, or from about 0.1% to about 2.3%, by weight of the composition, of a polysaccharide gum, preferably xanthan gum.

Preservative agent

The arthropod pest control compositions disclosed herein may comprise one or more preservatives. As used herein, a "preservative" is any substance or compound added to prevent decay, decomposition or deterioration. Preservatives may be natural or synthetic. The preservative may be an antimicrobial preservative that inhibits the growth of bacteria or fungi, including mold, or an antioxidant. Non-limiting examples of preservatives include potassium sorbate, tocopherols (e.g., tocopheryl acetate), calcium propionate, sodium nitrate, sodium nitrite, sulfites (sulfur dioxide, sodium bisulfite, potassium bisulfite, etc.), and disodium EDTA. The arthropod pest control composition disclosed herein may comprise from about 0.02% to about 4% by weight of the composition of a preservative, preferably a preservative selected from the group consisting of potassium sorbate, tocopherol, and mixtures thereof.

Dye

The arthropod pest control composition may comprise a dye or a colorant. Non-limiting examples of colorants include inorganic pigments (e.g., ultramarine blue), organic dyes, and micronutrients (e.g., iron, manganese, boron, copper, cobalt, molybdenum, and zinc salts). Colorants may be included to alter the aesthetics of the arthropod pest control composition. The compositions disclosed herein may comprise from about 0.001% to about 0.1%, preferably from about 0.005% to about 0.05%, more preferably from about 0.008% to about 0.02% of dye or colorant by weight of the composition.

Combination of two or more kinds of materials

A. An insecticidal composition comprising: from about 40% to about 95%, preferably from about 50% to about 90%, more preferably from about 55% to about 80%, even more preferably from about 58% to about 78%, even more preferably from about 60% to about 75%, most preferably from about 62% to about 72% water by weight of the composition; b. from about 0.01% to about 15%, preferably from about 0.1% to about 10%, more preferably from about 1% to about 5%, by weight of the composition, of potassium oleate; c. from about 1% to about 45%, preferably from about 1% to about 30%, more preferably from about 1% to about 25%, even more preferably from about 1% to about 15%, by weight of the composition, of isopropyl alcohol; d. optionally, from about 0.01% to about 15%, preferably from about 0.1% to about 8%, more preferably from about 0.4% to about 4%, by weight of the composition, of sodium bicarbonate; optionally, from about 0.01% to about 1%, preferably from about 0.01% to about 0.8%, more preferably from about 0.01% to about 0.6%, by weight of the composition, of anhydrous citric acid, citric acid monohydrate, or a combination thereof; f. from about 0.005% to about 15%, preferably from about 0.05% to about 12%, more preferably from about 0.5% to about 10%, even more preferably from about 1% to about 7%, by weight of the composition, of one or more active ingredients selected from the group consisting of: corn mint oil, peppermint oil, spearmint oil, rosemary oil, thyme oil, citronella oil, clove oil, cedar wood oil, and mixtures thereof, preferably selected from corn mint oil, spearmint oil, rosemary oil, thyme oil, and mixtures thereof, more preferably selected from corn mint oil, rosemary oil, and mixtures thereof; wherein the composition has a pH of about 4.5 to about 11.0, preferably about 7.0 to about 9.0, more preferably about 7.5 to about 8.5.

B. An insecticidal composition comprising: from about 40% to about 95%, preferably from about 50% to about 90%, more preferably from about 55% to about 80%, even more preferably from about 58% to about 78%, even more preferably from about 60% to about 75%, most preferably from about 62% to about 72% water by weight of the composition; b. from about 0.01% to about 15%, preferably from about 0.1% to about 10%, more preferably from about 1% to about 5%, by weight of the composition, of potassium oleate; c. from about 1% to about 45%, preferably from about 1% to about 30%, more preferably from about 1% to about 25%, even more preferably from about 1% to about 15%, by weight of the composition, of isopropyl alcohol; d. optionally, from about 0.01% to about 15%, preferably from about 0.1% to about 8%, more preferably from about 0.4% to about 4%, by weight of the composition, of sodium bicarbonate; optionally, from about 0.01% to about 1%, preferably from about 0.01% to about 0.8%, more preferably from about 0.01% to about 0.6%, by weight of the composition, of anhydrous citric acid, citric acid monohydrate, or a combination thereof; f. from about 0.005% to about 15%, preferably from about 0.05% to about 12%, more preferably from about 0.5% to about 10%, even more preferably from about 1% to about 7%, by weight of the composition, of one or more active ingredients selected from the group consisting of: eugenol, 2-phenylethyl propionate, menthol, menthone, thymol, carvone, camphor, methyl salicylate, p-isopropyl toluene, linalool, eucalyptol/1, 8-eucalyptol, alpha-pinene, borneol acetate, gamma-terpinene, and combinations thereof. Wherein the composition has a pH of about 4.5 to about 11.0, preferably about 7.0 to about 9.0, more preferably about 7.5 to about 8.5.

C. The insecticidal composition of paragraph a or B, wherein the composition is clear.

D. The insecticidal composition of any one of paragraphs a-D, wherein the composition is an oil-in-water emulsion.

E. The insecticidal composition of any one of paragraphs a-D, wherein the composition is substantially free of sodium lauryl sulfate.

F. The insecticidal composition of any one of paragraphs a-E, wherein the composition is packaged in a transparent container.

G. The insecticidal composition of any one of paragraphs a-F, wherein the composition further comprises from about 0.01% to about 0.5% tocopherol.

H. The insecticidal composition of any one of paragraphs a-G, wherein the composition is substantially free of mineral oil.

I. The insecticidal composition according to any one of paragraphs a-H wherein the composition comprises only food-grade ingredients.

J. The insecticidal composition of any one of paragraphs a-L, wherein the composition comprises from about 0.5% to about 7%, preferably from about 0.5% to about 5%, more preferably from about 0.5% to about 4%, by weight of the composition, rosemary oil.

K. The insecticidal composition of any one of paragraphs a-J, wherein the composition comprises from about 0.5% to about 7%, preferably from about 0.5% to about 5%, more preferably from about 0.5% to about 4%, corn mint oil by weight of the composition.

The insecticidal composition of any one of paragraphs a-K, wherein the composition comprises from about 0.5% to about 7%, preferably from about 0.5% to about 5%, more preferably from about 0.5% to about 4%, by weight of the composition, spearmint oil.

M. the insecticidal composition of any one of paragraphs a-L, wherein the composition comprises from about 0.5% to about 7%, preferably from about 0.5% to about 5%, more preferably from about 0.5% to about 4% rosemary oil by weight of the composition.

The insecticidal composition of any one of paragraphs a-M, wherein the composition comprises from about 0.5% to about 7%, preferably from about 0.5% to about 5%, more preferably from about 0.5% to about 4% citronella oil, by weight of the composition.

The insecticidal composition of any one of paragraphs a-N, wherein the composition comprises about 0.5% to about 7%, preferably about 0.5% to about 5%, more preferably about 0.5% to about 4%, cedar oil by weight of the composition.

The insecticidal composition of any one of paragraphs a-O, wherein the composition further comprises from about 0.001% to about 1%, preferably from about 0.01% to about 1%, more preferably from about 0.1% to about 0.8%, by weight of the composition, of a colorant selected from the group consisting of: ultramarine blue, red cabbage dye, beet dye, carrot dye, chlorophyll, and mixtures thereof.

The insecticidal composition of any one of paragraphs a-P, wherein the composition further comprises from about 0.1% to about 7.5%, preferably from about 0.5% to about 4.5%, more preferably from about 0.1% to about 2.3%, by weight of the composition, of a polysaccharide, preferably xanthan gum.

The insecticidal composition of any one of paragraphs a-Q, wherein the composition has a turbidity of less than about 20NTU, preferably less than about 5NTU, and greater than or equal to 0 NTU.

S. the insecticidal composition according to any one of paragraphs a-R wherein said composition has a b-x value of from about 0 to about 4, preferably from about 0 to about 2.

A method of controlling arthropod pests comprising: i) Contacting the arthropod pest with the insecticidal composition according to any one of paragraphs a-S; ii) optionally wiping excess composition from the adjacent surface.

Test method

Measurement of Hunter l.a.b. (CIE) b values

Yellow formation was measured using Hunter l.a.b. (CIE) method. Using HunterLab ColorFlexThe b value was measured by a spectrophotometer (HunterLab, 11491Sunset Hills Road,Reston,Virginia 20190). The method used is described in detail in "User's Manual for ColorFlex EZ Version 2.2.2". An average of four independent readings was recorded.

HunterLab ColorFlexThe spectrophotometer uses a xenon flash lamp to illuminate the sample. The light reflected by the sample is then separated into its component wavelengths by a dispersive grating. The relative intensities of light at different wavelengths along the visible spectrum (400-700 nm) are then analyzed to produce a digital result indicative of the sample color.

Turbidity degree

A turbidimeter is used to measure the turbidity of a pesticidal composition. The instrument measures the turbidity of a liquid in Nephelometric Turbidity Units (NTU). Methods for measuring turbidity are described in detail in the following references: hach 2100Q and 2100Qis User Manual, 6 th edition, 2021, 8 months of Hach company.

The measurement method determines a quantitative value of turbidity by evaluating the ratio of the main turbidity light scattering signal to the transmitted light scattering signal. This particular evaluation method provides a value between 0 and 1000NTU, where a greater NTU value indicates a more cloudy composition. In the middle of each test sample, a water control group can be measured to ensure proper device operation. For example, water may have a turbidity of about 1.11NTU and isopropyl alcohol may have a turbidity of about 0.15 NTU. It is believed that the improvement in emulsification of the active ingredient, particularly the hydrophobic active ingredient, results in lower NTU values.

Insect test

Material：

The insect used in the test was male german cockroach (Blattella germanica) from Benzon Research, inc. The insects were housed in a transparent PET cup (c-kc 24) covered with a transparent PET flat cover (c-k c626 ts) having a straw hole (cup and lid available from kart). The spray bottle was a clear PET bottle with 1.1%66SA7600 antistatic additive (PMP-91690456) with a Silgan Mixor MP 1.3CC atomizer (PMP-91690457). The additional material used in the test was filter paper, ol' Roy ^TM Kuggis white box with cover (10) ¹ / ₄ x 13 ² / ₄ x 6) ("test cartridge").

Method：

First, cockroaches were placed in a 4 ℃ refrigerator (in a container containing cockroaches) for 10 to 20 minutes, and cold anesthetized. If the cockroaches remain active after 10 to 20 minutes of cold anesthesia, they are returned to the 4 ℃ refrigerator for another 5 minutes to reduce the activity of the cockroaches and facilitate sample cup preparation.

The insects are then transferred to a large, shallow plastic container with a lid. The large plastic container is cooled on the ice bag (by placing the plastic container directly on the ice bag) to keep the insects cool during dispensing into the individual cups. When the cockroaches started to act, the most mobile cockroaches were first selected and sorted into individual cups (5 insects per cup) ready. Cockroaches were treated with soft-headed forceps. Cockroaches with leg movements were next selected.

Each sample cup was prepared by combining filter paper and an Ol' Roy ^TM Dog food is placed at the bottom of the cup for preparation. Water was sprayed onto the filter paper so that the cockroaches were not dehydrated overnight, and 5 cockroaches were placed in each cup. A cap was placed over each cup and the straw hole in each cap was sealed with tape.

After 5 cockroaches were dispensed per cup, the cup with the insect was left at room temperature to restore the insects to their normal activity level. Each test checks and confirms the movement of the insect. Only cups containing 5 live insects were used for data collection. Cups with less than 5 live insects may be used for informal screening or combination to prepare samples of 5 live insects.

Testing：

Each spray bottle was primed prior to testing by squeezing the trigger until a stable product spray was achieved. Spray (versus flow) settings were used. Each cup was placed in a test cartridge (Kuggis white cartridge) and inverted at the approximate center of the test cartridge (one sample cup at a time). The cup was then lifted and sprayed 3 to 5 times onto the cockroaches until each insect was visually confirmed to be wetted. Recording the tested video.

The incapacitation and imminent death of the cockroaches were recorded in video. Incapacitation is defined herein as the inability of the cockroaches to recover themselves or move in an upright, conscious manner. Incapacitation does not preclude the twitching of the wing, leg or antenna (in other words, an insect exhibiting a wing, leg or antenna twitching is still considered "knocked down" if it is unable to recover itself or move in an upright, conscious manner). Moribundity or moribund means that the cockroaches cannot recover themselves or move in an upright, conscious manner, and the wings, legs or antennae of the cockroaches do not exhibit any movement. Cockroach death refers to the situation in which the cockroach is immobilized when subjected to an external stimulus (e.g., a stab). Mortality was not measured or determined in the experiments described herein. Reviewing the video, the time of incapacitation and the time of imminent death of each insect were recorded.

The time to disability and time to death recorded in the table below are the average of two test replicates each containing 5 insects (per cup, as described above). In each test replicate of 5 insects, the time of disability and the time of imminent death of each of the 5 insects were recorded, and the average of the 5 disability times and the 5 imminent death times was calculated. The average of the 5 incapacitation times of the first test replicates and the average of the 5 incapacitation times of the second test replicates were then averaged and recorded in the table below. The average of the 5 endangered mortality times of the first test replicate and the average of the 5 endangered mortality times of the second test replicate were then averaged and recorded in the table below. Furthermore, for each test replicate, the incapacitation time and the imminent death time of insufficiently sprayed insects were excluded from calculation of the average incapacitation time and the average imminent death time.

Examples

EXAMPLE 1 addition of isopropanol to reduce disability and time to imminent death

The insecticidal compositions in table 1 were prepared by mixing the raw materials in a batch process. The insecticidal compositions of examples 1 to 4 differ only in the concentration of isopropyl alcohol and water. The results in table 1 show that with increasing isopropanol concentration, both the incapacitation and the time to imminent death decrease.

TABLE 1

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Example 2-clear composition

Some consumers may prefer a clear insecticidal composition without accepting any compromise in the effectiveness of the composition. The insecticidal compositions of examples 5 to 10 differ only in the concentration of potassium oleate and water. The results in table 2 show that both the disability and kill time increase with increasing potassium oleate levels.

TABLE 2

Composition (weight percentage)	5	6	7	8	9	10
							Oleic acid potassium salt	2.60	3.50	5.00	7.50	10.00	13.00
Corn peppermint oil	0.55	0.55	0.55	0.55	0.55	0.55
							Rosemary oil	2.67	2.67	2.67	2.67	2.67	2.67
Citronella oil	1.88	1.88	1.88	1.88	1.88	1.88
							Cedar wood oil (Texas)	0.53	0.53	0.53	0.53	0.53	0.53
Thyme oil	0.91	0.91	0.91	0.91	0.91	0.91
							Spearmint oil	0.06	0.06	0.06	0.06	0.06	0.06
Anhydrous isopropanol	20.00	20.00	20.00	20.00	20.00	20.00
							Glycerol	2.50	2.50	2.50	2.50	2.50	2.50
Deionized water	66.73	65.83	64.33	61.83	59.33	56.33
							Potassium citrate	0.92	0.92	0.92	0.92	0.92	0.92
Sodium bicarbonate	0.55	0.55	0.55	0.55	0.55	0.55
							Potassium sorbate	0.10	0.10	0.10	0.10	0.10	0.10
Incapacitation (seconds)	18.60	20.90	Not tested	23.25	Not tested	24.03
							Dying (seconds)	22.40	26.50	Not tested	25.50	Not tested	28.35
Clarity of the product ¹	Cloudiness	Clarifying	Clarifying	Clarifying	Clarifying	Clarifying
							Number of phases ¹	1	1	1	1	1	1

¹ Determined by visual observation of the composition at 23 ℃, wherein the single phase composition is stable.

EXAMPLE 3 sodium bicarbonate

The insecticidal compositions of examples 11 and 12 differed only in the concentration of sodium bicarbonate and water. The results in table 3 show that the addition of sodium bicarbonate reduced the disability and kill time.

TABLE 3 Table 3

Composition (weight percentage)	11	12
			Oleic acid potassium salt	2.60	2.60
Corn peppermint oil	0.55	0.55
			Citronella oil	1.88	1.88
Rosemary oil	2.67	2.67
			Thyme oil	0.91	0.91
Orchid (L.) KuntzeSesame oil	0.057	0.057
			Cedar wood oil (Texas)	0.53	0.53
Anhydrous isopropanol	20.0	20.0
			Glycerol	2.50	2.50
Deionized water	67.28	66.73
			Potassium citrate	0.92	0.92
Sodium bicarbonate	0.00	0.55
			Potassium sorbate	0.10	0.10
Incapacitation (seconds)	19.4	18.0
			Dying (seconds)	22.8	20.6

Example 4 preparation example

Tables 4 and 10 include a range of possible formulations according to the present disclosure. Tables 5-9 include a series of possible formulations according to the present disclosure, as well as disability time and imminent death time data for each formulation.

TABLE 4 Table 4

TABLE 5

TABLE 6

TABLE 7

TABLE 8

TABLE 9

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Table 10

	71	72	73	74	75	76	77
								Oleic acid potassium salt	1.00	1.00	1.00	1.00	1.00	2.60	1.00
Clove oil	0	0	0	0	0	0	0
								Corn peppermint oil	1.80	0.90	0	0.60	0.30	0	0.714
Citronella oil	0	0	0	0	0	0	0
								Rosemary oil	0	0.90	0	0	0.30	0	0.714
Thyme oil	0	0	0	0	0	0	0
								Geraniol	0	0	1.40	1.00	1.00	3.50	0
Spearmint oil	0	0	0	0	0	0	0
								Cedar wood oil (Texas)	0	0	0	0	0	0	0
Anhydrous isopropanol	18.0	18.0	18.0	18.0	18.0	18.0	18.8
								Glycerol	2.5	2.5	2.5	2.5	2.5	2.5	2.5
Deionized water	Qs	Qs	Qs	Qs	Qs	Qs	Qs
								Potassium citrate	0.92	0.92	0.92	0.92	0.92	0.92	0.92
Potassium sorbate	0.10	0.10	0.10	0.10	0.10	0.10	0.40

The dimensions and values disclosed herein are not to be understood as being strictly limited to the exact numerical values recited. Rather, unless otherwise indicated, each such dimension is intended to mean both the recited value and a functionally equivalent range surrounding that value. For example, a dimension disclosed as "40mm" is intended to mean "about 40mm".

Each document cited herein, including any cross-referenced or related patent or patent application, and any patent application or patent for which this application claims priority or benefit from, is hereby incorporated by reference in its entirety unless expressly excluded or otherwise limited. The citation of any document is not an admission that it is prior art with respect to the present invention, or that it is not entitled to any disclosed or claimed herein, or that it is prior art with respect to itself or any combination of one or more of these references. Furthermore, to the extent that any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this document shall govern.

While particular embodiments of the present invention have been illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. It is therefore intended to cover in the appended claims all such changes and modifications that are within the scope of this invention.

Claims

1. An insecticidal composition, the insecticidal composition comprising:

a. 40% to 95% by weight of the composition of water;

b. from 0.01% to 15% by weight of the composition of potassium oleate;

c. from 1% to 45% by weight of the composition of isopropanol;

d. optionally, from 0.01% to 15% by weight of the composition of sodium bicarbonate; and

e. optionally, from 0.01% to 1% by weight of the composition of anhydrous citric acid, citric acid monohydrate, or a combination thereof;

f. from 1% to 15% by weight of the composition of one or more active ingredients selected from the group consisting of: corn mint oil, peppermint oil, spearmint oil, rosemary oil, thyme oil, citronella oil, clove oil, cedar wood oil, cinnamon oil, geranium oil, eugenol, 2-phenylethyl propionate, menthol, menthone, thymol, carvone, camphor, methyl salicylate, p-isopropyl toluene, linalool, geraniol, lauryl acetate, cinnamyl alcohol, cinnamaldehyde, citronellol, eucalyptol/1, 8-eucalyptol, alpha-pinene, borneol acetate, gamma-terpinene, and combinations thereof;

Wherein the composition has a pH of 4.5 to 11.0.

2. The insecticidal composition of claim 1, wherein the composition is clear.

3. A pesticidal composition according to any one of the preceding claims, wherein the composition is an oil-in-water emulsion.

4. A pesticidal composition according to any one of the preceding claims, wherein the composition is substantially free of sodium lauryl sulphate.

5. An insecticidal composition according to any one of the preceding claims wherein the composition is packaged in a transparent container.

6. An insecticidal composition according to any one of the preceding claims wherein the composition further comprises from 0.01% to 0.5% tocopherol.

7. A pesticidal composition according to any one of the preceding claims, wherein the composition is substantially free of mineral oil.

8. A pesticidal composition according to any one of the preceding claims, wherein the composition comprises only food-grade ingredients.

9. A pesticidal composition according to any one of the preceding claims, wherein the composition comprises from 0.5% to 7% by weight of the composition of one or more active ingredients selected from the group consisting of: rosemary oil, corn mint oil, spearmint oil, thyme oil, citronella oil, cedar oil, and combinations thereof.

10. An insecticidal composition according to any one of the preceding claims wherein the composition further comprises from 0.001% to 1% by weight of the composition of a colorant selected from the group consisting of: ultramarine blue, red cabbage dye, beet dye, carrot dye, chlorophyll, and mixtures thereof.

11. An insecticidal composition according to any one of the preceding claims wherein the composition further comprises from 0.1% to 7.5% polysaccharide by weight of the composition.

12. An insecticidal composition according to any one of the preceding claims wherein the composition has a turbidity of less than 20NTU and greater than or equal to 0 NTU.

13. A pesticidal composition according to any one of the preceding claims, wherein the composition has a b-value of 0 to 4.

14. A method of controlling an arthropod pest, the method comprising: i) Contacting the arthropod pest with the insecticidal composition of any one of the preceding claims; ii) optionally wiping excess composition from the adjacent surface.