CN117653926A - Xerophthalmia laser therapy appearance with pulse laser array - Google Patents
Xerophthalmia laser therapy appearance with pulse laser array Download PDFInfo
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- CN117653926A CN117653926A CN202311792432.6A CN202311792432A CN117653926A CN 117653926 A CN117653926 A CN 117653926A CN 202311792432 A CN202311792432 A CN 202311792432A CN 117653926 A CN117653926 A CN 117653926A
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- 238000002647 laser therapy Methods 0.000 title description 2
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- 229910002601 GaN Inorganic materials 0.000 claims description 8
- JMASRVWKEDWRBT-UHFFFAOYSA-N Gallium nitride Chemical compound [Ga]#N JMASRVWKEDWRBT-UHFFFAOYSA-N 0.000 claims description 8
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Abstract
The invention relates to a xerophthalmia laser therapeutic apparatus with a pulse laser array. The invention comprises an eyeball protecting cover body, an upper eyelid laser array and a lower eyelid laser array which are respectively arranged on the eyeball protecting cover body and respectively connected to a driving circuit, wherein the driving circuit comprises a voltage module, a protecting module, a switch module, an energy storage module and a control module; the voltage module is respectively connected with the protection module and the switch module, the energy storage module is respectively connected with the protection module and the switch module, the upper eyelid laser array and the lower eyelid laser array are respectively connected with the energy storage module, and the control module is connected with the switch module; the control module is used for controlling the on-off of the switch module, and when the switch module is closed, the upper eyelid laser array and the lower eyelid laser array generate pulse laser emitted to the upper eyelid and the lower eyelid so as to act on the meibomian glands around the eyesocket. The invention can improve the treatment effect and reduce the damage to target tissues.
Description
Technical Field
The invention relates to the technical field of semiconductor photoelectrons, in particular to a xerophthalmia laser therapeutic instrument with a pulse laser array.
Background
Dry eye is a tear secretion disorder ocular disease with dry eyes as a main symptom, often accompanied by itching, foreign body sensation, burning sensation of eyes, photophobia, blurred vision, vision fluctuation and the like, and is mainly caused by unstable tear film and loss of homeostasis, i.e., meibomian gland dysfunction, caused by excessive evaporation. The mainstream treatment method for xerophthalmia comprises hot compress treatment, low level light treatment and meibomian gland massage.
In connection with Low Level Laser Therapy (LLLT), which refers to the application of light for the purpose of promoting tissue repair, reducing inflammation and producing analgesia, low power light sources (lasers or LEDs) are typically used. Non-thermal, non-invasive cell photoactivation is achieved by manipulating the wavelength and power density of the incident light. Because of the low power, the treatment does not result in a significant temperature rise in the treated tissue, and therefore, the overall tissue structure is not significantly altered. The main uses in the medical field are in reducing inflammation, promoting wound healing, and treating pain and neurological diseases.
The prior pulse therapy needs manual operation, can not ensure that each irradiation precisely acts on meibomian glands, and has short effective acting time and long heat dissipation time because frequency and pulse width can not be adjusted, and the important principle of photo-biological regulation treatment is that the light dose does not exceed the damage threshold of the tissue to be treated.
Disclosure of Invention
Therefore, the invention provides a xerophthalmia laser therapeutic apparatus with a pulse laser array, which adopts the pulse laser array to treat, can precisely act on the meibomian glands around the eye socket, improves the therapeutic effect, and can control the light dosage and reduce the damage to target tissues by adjusting the pulse width and the working frequency of the laser.
In order to solve the technical problems, the invention provides a xerophthalmia laser therapeutic apparatus with a pulse laser array, which comprises an eyeball protecting cover body, an upper eyelid laser array and a lower eyelid laser array which are respectively arranged on the eyeball protecting cover body and correspond to the positions of an upper eyelid and a lower eyelid, wherein the upper eyelid laser array and the lower eyelid laser array are respectively connected to a driving circuit, and the driving circuit comprises a voltage module, a protecting module, a switch module, an energy storage module and a control module;
the voltage module is respectively connected with the protection module and the switch module, the energy storage module is respectively connected with the protection module and the switch module, the upper eyelid laser array and the lower eyelid laser array are respectively connected with the energy storage module, and the control module is connected with the switch module;
the control module is used for controlling the on-off of the switch module, charging the energy storage module through the voltage module when the switch module is closed, and discharging the energy storage module to the upper eyelid laser array and the lower eyelid laser array when the switch module is opened so that the upper eyelid laser array and the lower eyelid laser array generate pulse laser emitted to the upper eyelid and the lower eyelid to act on meibomian glands around the eye socket.
In one embodiment of the present invention, the upper eyelid laser array and the lower eyelid laser array each comprise a plurality of laser arrays disposed in parallel, and each of the laser arrays is correspondingly distributed at meibomian gland locations in the upper eyelid and the lower eyelid.
In one embodiment of the present invention, the number of lasers in the laser array at both end positions of the upper eyelid and/or lower eyelid is smaller than the number of lasers in the laser array at the middle position of the upper eyelid and/or lower eyelid.
In one embodiment of the present invention, the upper eyelid laser array and the lower eyelid laser array employ vertical cavity surface semiconductor laser arrays emitting laser light with a wavelength of 850nm and an energy density of less than 100 mW/cm2.
In one embodiment of the invention, the voltage module employs a constant voltage source.
In one embodiment of the invention, the switch module employs a gallium nitride switch.
In one embodiment of the invention, the protection module employs a protection diode.
In one embodiment of the present invention, the control module uses an FPGA module or a single chip microcomputer.
In one embodiment of the invention, the energy storage module uses an energy storage capacitor.
Compared with the prior art, the technical scheme of the invention has the following advantages:
the xerophthalmia laser therapeutic apparatus with the pulse laser array adopts the design of the pulse laser array, ensures that each treatment can accurately act on meibomian glands, and improves the treatment accuracy; the pulse laser array can adjust the pulse frequency and the pulse width, has long effective action time, can ensure better treatment effect, and can not cause obvious temperature rise to the tissue to be treated; the eyeball protective cover body is adopted for covering, so that the cornea, iris and crystalline lens of a patient are effectively protected, and the influence on other tissues of the eyelid is reduced; the patient only needs to wear the eye mask of the therapeutic apparatus, so that the quick treatment can be performed without manual operation, and the method is convenient and quick.
The therapeutic apparatus adopts pulse light to stimulate meibomian gland to produce normal meibomian ester, reduces gland obstruction, can improve tear secretion problem, reduce inflammatory reaction, and improve therapeutic effect; the light source has a small wavelength range and low energy density, so the light source can not harm human bodies, and the eyeball protecting cover body can be adopted for comprehensively protecting the cornea and other parts during treatment.
Drawings
In order that the invention may be more readily understood, a more particular description of the invention will be rendered by reference to specific embodiments thereof that are illustrated in the appended drawings.
FIG. 1 is a laser array layout of the therapeutic apparatus of the present invention.
Figure 2 is a distribution diagram of the meibomian glands of the human body.
Fig. 3 is a schematic diagram of the system configuration of the therapeutic apparatus of the present invention.
Fig. 4 is a schematic diagram of an equivalent circuit of the therapeutic apparatus of the present invention.
Description of the specification reference numerals:
100. a voltage module; 200. a protection module; 300. a switch module; 400. an energy storage module; 500. a control module; 600. an eyeball protective cover body; 610. an upper eyelid laser array; 620. a lower eyelid laser array.
Detailed Description
The present invention will be further described with reference to the accompanying drawings and specific examples, which are not intended to be limiting, so that those skilled in the art will better understand the invention and practice it.
In the present invention, if directions (up, down, left, right, front and rear) are described, they are merely for convenience of description of the technical solution of the present invention, and do not indicate or imply that the technical features must be in a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention.
In the present invention, "a plurality of" means one or more, and "a plurality of" means two or more, and "greater than", "less than", "exceeding", etc. are understood to not include the present number; "above", "below", "within" and the like are understood to include this number. In the description of the present invention, the description of "first" and "second" if any is used solely for the purpose of distinguishing between technical features and not necessarily for the purpose of indicating or implying a relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.
In the present invention, unless clearly defined otherwise, terms such as "disposed," "mounted," "connected," and the like should be construed broadly and may be connected directly or indirectly through an intermediate medium, for example; the connecting device can be fixedly connected, detachably connected and integrally formed; can be mechanically connected, electrically connected or capable of communicating with each other; may be a communication between two elements or an interaction between two elements. The specific meaning of the words in the invention can be reasonably determined by a person skilled in the art in combination with the specific content of the technical solution.
Referring to fig. 1 to 3, the dry eye laser therapeutic apparatus with a pulse laser array according to the present invention includes an eye protection cover 600, and an upper eyelid laser array 610 and a lower eyelid laser array 620 respectively disposed on the eye protection cover 600 and corresponding to the positions of the upper eyelid and the lower eyelid, wherein the upper eyelid laser array 610 and the lower eyelid laser array 620 are respectively connected to a driving circuit, and the driving circuit is designed on a printed circuit board and disposed in the eye mask at a position close to the laser array, so as to avoid the influence of excessive routing on the power of the laser. The driving circuit comprises a voltage module 100, a protection module 200, a switch module 300, an energy storage module 400 and a control module 500;
the voltage module 100 is respectively connected with the protection module 200 and the switch module 300, the energy storage module 400 is respectively connected with the protection module 200 and the switch module 300, the upper eyelid laser array 610 and the lower eyelid laser array 620 are respectively connected with the energy storage module 400, and the control module 500 is connected with the switch module 300;
the control module 500 is configured to control the switching module 300 to be turned on and off, charge the energy storage module 400 through the voltage module 100 when the switching module 300 is turned on, and discharge the energy storage module 400 to the upper eyelid laser array 610 and the lower eyelid laser array 620 when the switching module 300 is turned off, so that the upper eyelid laser array 610 and the lower eyelid laser array 620 generate pulsed laser light emitted to the upper eyelid and the lower eyelid to act on the meibomian glands around the eye socket.
The treatment principle is as follows: the laser emits pulse light to the tail end of the meibomian gland around the eye socket, and the light is aimed at the upper eyelid and the lower eyelid at the same time, so that the gland is induced to discharge normal meibomian, the recovery of the gland is promoted, and the protein and lipid component content in tears is improved; reduces the updating of the gland epithelial cells and relieves the gland obstruction. The laser is an application of a red or near infrared low-power light source, and can promote tissue repair, reduce inflammation and relieve pain.
In some embodiments, since the meibomian glands under the eyelid of the human eye are arranged in parallel, the upper eyelid laser array 610 and the lower eyelid laser array 620 each comprise a plurality of parallel arranged laser arrays, and each of the laser arrays is correspondingly arranged at the meibomian gland position in the upper eyelid and the lower eyelid, the column spacing is about the spacing of the adjacent meibomian glands.
In some embodiments, the number of lasers in the laser array at the locations of both ends of the upper and/or lower eyelid is less than the number of lasers in the laser array at the locations of the middle of the upper and/or lower eyelid. The lasers are distributed in an array, the irradiation range of the lasers is matched with the shape of the meibomian glands around the eyeball, each laser is arranged in the eyeball protective cover body 600, and a patient only needs to wear the eyeshade of the therapeutic instrument during treatment, so that the method is convenient and quick, the accuracy of laser treatment of the meibomian glands is improved, and the influence on other tissues of the eyelid is reduced; during treatment, the eyeball protecting cover 600 is used for covering eyes and fully protecting cornea, iris and crystalline lens of a patient.
Since the eyeball protecting cover 600 prevents the photosensitive area of the eyeball from being irradiated by the laser, but the partial structure of the gland is covered by the eyeball protecting cover 600, the treatment intensity can be moderately improved to achieve the treatment effect, and the laser emitted by the lasers in the upper eyelid laser array 610 and the lower eyelid laser array 620 has the wavelength of 850nm and the energy density of less than 100 mW/cm < 2 >.
In some embodiments, the laser employs a vertical cavity surface semiconductor laser array, the voltage module 100 employs a constant voltage source, and the constant voltage source is converted into stable low voltage direct current by alternating current after the eyeshade is powered on; the switch module 300 adopts a gallium nitride switch, and the device type can be EPC2016C; the protection module 200 adopts a protection diode, and the unidirectional conductivity of the diode is applied to protect the charge on the storage capacitor from being damaged due to countercurrent entering the voltage source; the control module 500 is controlled by an FPGA or a singlechip, so that stable voltage signals with adjustable frequency and adjustable pulse width can be output; the energy storage module 400 adopts an energy storage capacitor, and the circuit can be regarded as an RLC loop when the capacitor discharges, and the energy storage capacitor can ensure that the circuit works in an underdamped state while the capacity of the energy storage capacitor is as large as possible. The pulse laser can be output through the turn-off of the gallium nitride switch, wherein the FPGA module or the singlechip controls the gallium nitride switch by dividing the clock and outputting signals with different frequencies and duty ratios. The circuit adopting the structure is shown in fig. 4, wherein the anode of the constant voltage source is connected with the anode of the protection diode, and the cathode of the protection diode is sequentially connected with the energy storage capacitor, the gallium nitride switch and the cathode of the constant voltage source; the upper eyelid laser array 610 and the lower eyelid laser array 620 can be equivalently a plurality of groups of light emitting diodes and capacitors connected in parallel to both ends of the energy storage capacitor and connected in series by parasitic inductance, the principle being that: when the switch is closed, the power supply charges the energy storage capacitor; when the switch is opened, the charges stored by the upper plate of the energy storage capacitor can only flow to the laser array due to the action of the protection diode, which is equivalent to pulse discharge of the laser array once, and the switch is closed after all charges are consumed, and the process is repeated.
When the gallium nitride switch is closed, the constant voltage source charges the energy storage capacitor, and when the gallium nitride switch is opened, the energy storage capacitor discharges to the laser loop, so that pulse driving is realized. The FPGA module can control the frequency and the duty ratio, the size of the laser pulse can be improved by changing the voltage of the constant voltage source, and on the premise of having an effective treatment effect, the damage to the periphery of the target tissue is avoided.
By the arrangement, due to the luminous characteristics of the laser, the treatment efficiency of the laser is not defined by the output power of the laser, but by the effective dose transmitted to the target tissue at a specific wavelength, the proper pulse width can be selected according to the cooling necessary time of the tissue around the treatment target, and the laser can be controlled to alternately work among columns and rows, so that adjacent glands alternately irradiate treatment; the pulse frequency may also be reduced if necessary, but a prolonged treatment time may be required for the therapeutic effect.
The intense pulsed light is one of the current rapid and effective modes of clinical dry eye treatment, can effectively treat dry eye with meibomian gland dysfunction and mite type dry eye, and can also be used for treating blepharitis and hordeolum. By selective photothermal action, the abnormally dilated capillaries around the eyelid are closed, inflammatory factors and demodex which cause meibomian gland dysfunction are eliminated, and eyelid bacterial load is reduced; meanwhile, the composition can dredge meibomian glands, soften meibum and promote secretion and discharge of the meibum. The invention overcomes the problems that the pulse therapy method needs manual operation, can not ensure that each irradiation precisely acts on meibomian glands, and has short effective acting time and long heat dissipation time due to the selection of frequency and pulse width, and the important principle of photo-biological regulation therapy is that the light dosage does not exceed the damage threshold of the tissue to be treated. On the basis of adopting pulse light treatment, the invention adjusts the irradiation mode of the laser according to the physique of a patient by a special laser arrangement mode, adjusts the pulse width of the laser and strictly controls the effective dose aiming at target tissues in the light treatment. The existence of the protective cover prevents the photosensitive area of the eyeball from being irradiated by the laser, but has the defect that part of the structure of the gland is covered by the protective cover, so that the treatment intensity can be moderately improved to achieve the treatment effect.
Before treatment, skin photosensitivity test should be performed on the patient, and a proper irradiation mode is selected according to the test result, so as to adjust the pulse width and the working frequency of the laser. Then, the treatment is carried out, and the gel for photon treatment is smeared on the patient to protect the skin before the therapeutic apparatus is worn. After the application, the patient closes eyes, wears the eyeshade to cover the orbit part, protects the photosensitive area of the eyeball in the treatment process, ensures that laser rays can be effectively irradiated to the meibomian gland area for treatment, and fully carries out cold compress and heat dissipation after the treatment is finished, thereby reducing skin thermal injury.
Finally, it should be noted that the above-mentioned embodiments are only for illustrating the technical solution of the present invention, and not for limiting the same, and although the present invention has been described in detail with reference to examples, it should be understood by those skilled in the art that modifications and equivalents may be made to the technical solution of the present invention without departing from the spirit and scope of the technical solution of the present invention, and all such modifications and equivalents are intended to be encompassed in the scope of the claims of the present invention.
Claims (9)
1. A dry eye laser therapeutic apparatus with a pulse laser array, characterized by comprising an eyeball protecting cover body (600), and an upper eyelid laser array (610) and a lower eyelid laser array (620) which are respectively arranged on the eyeball protecting cover body (600) and correspond to the positions of an upper eyelid and a lower eyelid, wherein the upper eyelid laser array (610) and the lower eyelid laser array (620) are respectively connected to a driving circuit, and the driving circuit comprises a voltage module (100), a protecting module (200), a switching module (300), an energy storage module (400) and a control module (500);
the voltage module (100) is respectively connected with the protection module (200) and the switch module (300), the energy storage module (400) is respectively connected with the protection module (200) and the switch module (300), the upper eyelid laser array (610) and the lower eyelid laser array (620) are respectively connected with the energy storage module (400), and the control module (500) is connected with the switch module (300);
the control module (500) is used for controlling the on and off of the switch module (300), charging the energy storage module (400) through the voltage module (100) when the switch module (300) is closed, and discharging the energy storage module (400) to the upper eyelid laser array (610) and the lower eyelid laser array (620) when the switch module (300) is opened, so that the upper eyelid laser array (610) and the lower eyelid laser array (620) generate pulse laser emitted to the upper eyelid and the lower eyelid to act on meibomian glands around eyesockets.
2. The dry eye laser treatment apparatus with pulsed laser array of claim 1, wherein the upper eyelid laser array (610) and the lower eyelid laser array (620) each comprise a plurality of parallel arranged laser arrays, and each of the laser arrays is correspondingly distributed at meibomian gland locations in the upper eyelid and the lower eyelid.
3. A dry eye laser treatment apparatus with a pulsed laser array according to claim 2, wherein the number of lasers in the laser array at both end positions of the upper eyelid and/or lower eyelid is smaller than the number of lasers in the laser array at middle positions of the upper eyelid and/or lower eyelid.
4. The dry eye laser treatment apparatus according to claim 1, wherein the pulsed laser array,the laser is characterized in that the upper eyelid laser array (610) and the lower eyelid laser array (620) adopt vertical cavity surface semiconductor laser arrays, the emitted laser wavelength is 850nm, and the energy density is less than 100 mW/cm 2 。
5. A dry eye laser treatment apparatus with a pulsed laser array according to claim 1, characterized in that the voltage module (100) employs a constant voltage source.
6. The dry eye laser treatment apparatus with the pulsed laser array of claim 1, wherein the switching module (300) employs gallium nitride switches.
7. The dry eye laser treatment apparatus with the pulse laser array according to claim 1, wherein the protection module (200) employs a protection diode.
8. The dry eye laser therapeutic apparatus with pulse laser array according to claim 1, wherein the control module (500) adopts an FPGA module or a single chip microcomputer.
9. The dry eye laser treatment apparatus with the pulsed laser array according to claim 1, wherein the energy storage module (400) employs an energy storage capacitor.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311792432.6A CN117653926A (en) | 2023-12-22 | 2023-12-22 | Xerophthalmia laser therapy appearance with pulse laser array |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202311792432.6A CN117653926A (en) | 2023-12-22 | 2023-12-22 | Xerophthalmia laser therapy appearance with pulse laser array |
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| CN117653926A true CN117653926A (en) | 2024-03-08 |
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| CN202311792432.6A Pending CN117653926A (en) | 2023-12-22 | 2023-12-22 | Xerophthalmia laser therapy appearance with pulse laser array |
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| Country | Link |
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- 2023-12-22 CN CN202311792432.6A patent/CN117653926A/en active Pending
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