CN117653218A - Device for positioning and sampling tissues in and around cavity - Google Patents
Device for positioning and sampling tissues in and around cavity Download PDFInfo
- Publication number
- CN117653218A CN117653218A CN202311715283.3A CN202311715283A CN117653218A CN 117653218 A CN117653218 A CN 117653218A CN 202311715283 A CN202311715283 A CN 202311715283A CN 117653218 A CN117653218 A CN 117653218A
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- catheter
- sampling
- positioning
- around
- fixing disc
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- 238000005070 sampling Methods 0.000 title claims abstract description 100
- 230000001681 protective effect Effects 0.000 claims description 28
- 239000003223 protective agent Substances 0.000 claims description 8
- 239000000835 fiber Substances 0.000 claims description 6
- 239000000314 lubricant Substances 0.000 claims description 5
- 239000004696 Poly ether ether ketone Substances 0.000 claims description 3
- 239000003883 ointment base Substances 0.000 claims description 3
- 239000004033 plastic Substances 0.000 claims description 3
- 229920003023 plastic Polymers 0.000 claims description 3
- 239000004417 polycarbonate Substances 0.000 claims description 3
- 229920000515 polycarbonate Polymers 0.000 claims description 3
- 229920002530 polyetherether ketone Polymers 0.000 claims description 3
- 206010059313 Anogenital warts Diseases 0.000 abstract description 9
- 208000015181 infectious disease Diseases 0.000 abstract description 9
- 238000000034 method Methods 0.000 abstract description 9
- 238000009792 diffusion process Methods 0.000 abstract description 5
- 210000001519 tissue Anatomy 0.000 description 10
- 239000000463 material Substances 0.000 description 9
- 210000003708 urethra Anatomy 0.000 description 9
- 230000003902 lesion Effects 0.000 description 6
- 238000002428 photodynamic therapy Methods 0.000 description 6
- 210000000436 anus Anatomy 0.000 description 4
- 210000004400 mucous membrane Anatomy 0.000 description 4
- 238000012552 review Methods 0.000 description 4
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 238000005461 lubrication Methods 0.000 description 3
- 210000001215 vagina Anatomy 0.000 description 3
- 241000701806 Human papillomavirus Species 0.000 description 2
- 208000000260 Warts Diseases 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000004807 localization Effects 0.000 description 2
- 201000010153 skin papilloma Diseases 0.000 description 2
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 208000032420 Latent Infection Diseases 0.000 description 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 1
- 208000019802 Sexually transmitted disease Diseases 0.000 description 1
- 206010065584 Urethral stenosis Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 210000002255 anal canal Anatomy 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 208000037771 disease arising from reactivation of latent virus Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 229960004194 lidocaine Drugs 0.000 description 1
- 238000002504 lithotomy Methods 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 210000003899 penis Anatomy 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 201000001988 urethral stricture Diseases 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 210000003905 vulva Anatomy 0.000 description 1
Landscapes
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The invention discloses a device for positioning and sampling tissues in and around a cavity, which relates to the technical field of sample sampling, in particular to a device for positioning and sampling tissues in and around a cavity, comprising a guide pipe, a sampling rod, a sampling brush, a protection pipe and a protection pipe fixing disc; the catheter is a hollow catheter with two open ends, the outer surface of the catheter is provided with catheter graduations, the sampling brush is arranged at the far end of the sampling rod, the sampling rod is inserted into the protecting tube through the protecting tube fixing disc, the protecting tube is inserted into the catheter, and the protecting tube fixing disc is arranged at the near end of the protecting tube and fixedly connected with the catheter; meanwhile, misjudgment caused by instrument pollution and infection diffusion caused by instrument operation in the repeated sampling process are avoided, and the clinical difficulty that condyloma acuminatum is positioned inaccurately in the cavity and tissues around the cavity is effectively solved.
Description
Technical Field
The invention relates to the technical field of specimen sampling, in particular to a device for positioning and sampling tissues in and around a cavity.
Background
Condyloma acuminatum is one kind of sexually transmitted disease caused by human papilloma virus (Human papillomavirus HPV) infection and is characterized by skin and mucous membrane wart hyperplasia, and is preferably applied to prepuce, glans, urethral orifice, perianal, vulva, cervical, vagina and other parts. Condyloma acuminatum in the cavity of urethra, anus, etc. is a great difficulty for the clinician. Due to the reasons of more folds, poor visual field, inaccurate positioning and the like of mucous membranes in the cavity, the recurrence rate of condyloma acuminatum after the traditional operation is up to 70 percent, and the mucous membrane has large damage and more bleeding, and is easy to cause complications such as urethral stricture and the like. With the development of medical technology, photodynamic therapy has been strongly recommended in condyloma acuminatum diagnosis and treatment guidelines, and is the first treatment method of condyloma acuminatum in the cavity, particularly in the urethra. Photodynamic therapy can effectively clear latent infection focus by targeting condyloma acuminatum lesion tissues and protect normal tissues from damage, thereby reducing recurrence. Thus, photodynamic therapy first requires clear lesion localization, but no relevant guidelines and expert consensus currently direct HPV normalized material.
The method for monitoring HPV typing capacity of a fixed-point sampling line under direct vision of a urethroscope or an anoscope is a commonly adopted material taking method at present, but photodynamic therapy is carried out for 4-6 times as a treatment course, and the HPV typing capacity is required to be sampled and monitored before and after each photodynamic therapy, so that the curative effect is evaluated, the subsequent treatment scheme is formulated, and the patient is additionally painful and huge economic burden is brought by multiple urethroscopes or anoscopes; in addition, because warts are removed after treatment, localization is blurred during local latent focus review, and deviation is increased due to the fact that different doctors draw materials. CN202408966U discloses a urethral sampler, but it has the disadvantages that its device can only sample once, it needs to use multiple devices and repeatedly insert into the urethra for multipoint sampling, and infection can spread during its operation of inserting into the urethra, and it only takes materials for the urethra; CN216702569U discloses a flexible rectal sampling brush, but its device is also only sampled once, it requires multiple devices and repeated insertion into the rectum for multipoint sampling, and during its insertion into the anus may spread infection, and it is only for intrarectal sampling; in addition, CN113425331a discloses a sampler for noninvasive colorectal or anal canal and a use method thereof, although the device can achieve sectional positioning sampling, the range of positioning sampling sections is large, the range of positioning sampling sections is a plurality of centimeters, the accuracy is poor, and the sampler is only used for intra-anal sampling, and does not relate to positioning sampling of the channels such as urethra, vagina, cervical canal and the like and surrounding tissues thereof.
Therefore, how to provide a more ideal in clinic in-cavity positioning sampling device, which can accurately and objectively determine the lesion part, avoid misjudgment and infection diffusion caused by instrument operation, and reduce the discomfort and economic burden of the patient in sampling materials, thereby improving the photodynamic therapy efficiency and the medical accessibility of the patient review is a problem which needs to be solved by the technicians in the field.
Disclosure of Invention
In view of the above, the invention provides a device for positioning and sampling tissues in and around a cavity, which can more accurately and objectively position the infection parts in and around the cavity, realize fixed-point area treatment, avoid misjudgment and infection diffusion caused by instrument operation, reduce recurrence, lighten the economic burden of a patient and is beneficial to efficacy evaluation after treatment.
In order to solve the technical problems, the invention adopts the following technical scheme:
the device comprises a catheter, a sampling rod, a sampling brush, a protection tube and a protection tube fixing disc; the catheter is a hollow catheter with two open ends, catheter scales are arranged on the outer side of the catheter, the sampling brush is arranged at the far end of the sampling rod, the sampling rod penetrates through the fixing disc of the protection tube, is inserted into the protection tube and is inserted into the catheter together, and the fixing disc of the protection tube is arranged at the near end of the protection tube and is fixedly connected with the catheter.
Further, the catheter material is a plastic material such as medical polycarbonate or polyether-ether-ketone.
Further, the catheter is externally coated with a lubrication protective agent, and the lubrication protective agent is an ointment matrix.
Further, the diameter of the part of the protective tube inserted into the catheter is slightly smaller than that of the catheter, and the length and the diameter of the protective tube are the same as those of the catheter.
Furthermore, the diameter of the fixing disc of the protection tube is larger than that of the catheter, two fixing disc grooves are respectively formed in the upper portion and the lower portion of the fixing disc, and the two fixing disc grooves are anastomosed with the opening at the proximal end of the catheter and used for fixing the catheter and the protection tube, so that the fixing is more accurate and the fixing is not easy to shift.
Further, the lower edge of the protective tube fixing disc is provided with a magnetic attraction device at the lower edge of the protective tube fixing disc, which can magnetically attract the magnetic attraction device of the catheter near end hand-held handle on the hand-held handle, so that the catheter and the protective tube can be better fixed.
Further, the fixed disc surface of the protection tube is provided with fixed disc direction marks and fixed disc scales.
Further, the sampling wand is at least 2-3cm longer than the catheter.
Further, the sampling brush is made of a fiber soft brush.
Further, the catheter comprises a catheter proximal hand-held handle which is positioned at the proximal end of the catheter and is used for facilitating the operation and the convenient fixation of the catheter after positioning.
Further, a magnetic attraction device is arranged below the catheter proximal end handheld handle and can magnetically attract the lower edge magnetic attraction device of the protective tube fixing disc, so that the catheter and the protective tube are further fixed.
The invention has the beneficial effects that:
the invention can accurately determine the lesion position and range through catheter graduation, fixed disc azimuth mark and fixed disc graduation to condyloma acuminatum in the cavity and surrounding tissues; the sampling rod and the protective tube avoid misjudgment caused by instrument pollution and infection diffusion caused by instrument operation in the repeated sampling process, and the fixed-point treatment can be carried out on the premise of ensuring the treatment effectiveness, so that the pain and the economic burden of a patient can be reduced, and the clinical difficulty of inaccurate positioning of the condyloma acuminatum in the cavity and tissues around the cavity can be effectively solved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following description will briefly explain the drawings used in the embodiments or the description of the prior art, and it is obvious that the drawings in the following description are only embodiments of the present invention, and other drawings can be obtained according to the provided drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic longitudinal section of a sampling brush in a catheter of a sampling device according to the present invention;
FIG. 2 is a schematic longitudinal section of the sampling device of the present invention in a sampling state of the sampling brush;
FIG. 3 is a schematic cross-sectional view of a sampling device according to the present invention (from a distal to proximal perspective);
FIG. 4 is a schematic diagram of a sampling device according to the present invention;
FIG. 5 is a schematic view of a proximal handle of a catheter of the sampling device of the present invention;
FIG. 6 is a schematic diagram of a sampling device according to the present invention.
Wherein, in the figure:
1-a catheter; 2-sampling rod; 3-protecting tube; 4-a lubrication protecting agent; 5-catheter graduations; 11-catheter distal opening; 12-catheter proximal opening; 13-a catheter proximal handle; 21-sampling brush, 31-protecting tube fixing plate; 32-a fixed disk groove; 33-fixed disk azimuth identification; 34-fixed disk graduations; 35-a magnetic attraction device of a hand-held handle at the proximal end of the catheter; 36-the magnetic attraction device at the lower edge of the protective tube fixing disc.
Detailed Description
Referring to fig. 1-6, a device for positioning and sampling tissue in and around a cavity provided by the invention comprises a catheter 1, a sampling rod 2, a sampling brush 21, a protection tube 3 and a protection tube fixing disc 31; the catheter 1 is a hollow catheter with two open ends, a catheter scale 5 is arranged on the outer side of the catheter 1 and used for positioning a specific position in a catheter insertion cavity, different parts of the length and the diameter of the catheter 1 and patients can be of different types (as shown in fig. 6), the sampling brush 21 is arranged at the far end of the sampling rod 2, the sampling rod 2 penetrates through the protection tube fixing disc 31 and is inserted into the catheter 1, the protection tube 3 is used for separating the sampling rod 2 from the catheter 1, a new protection tube 3 can be replaced after sampling is completed to avoid misjudgment caused by instrument pollution and infection diffusion caused by instrument operation in the repeated sampling process, and the protection tube fixing disc 31 is arranged at the proximal end of the protection tube 3 and fixedly connected with the protection tube 3 and used for fixing the catheter 1 and the protection tube 3.
Further, the catheter 1 is made of medical plastics such as polycarbonate or polyether-ether-ketone.
Further, the catheter 1 is coated with a lubricant and protecting agent 4, the lubricant and protecting agent 4 is an ointment base such as vaseline, and is mixed with lidocaine or interferon, so that the catheter has the functions of lubricant and protecting and avoiding bringing virus into the deep part of the urethra, and the ointment base is transparent, so that the reading of the catheter graduation 5 is not affected.
Further, the pipe diameter of the part of the protection pipe 3 inserted into the guide pipe 4 is slightly smaller than that of the guide pipe 4, the length and the diameter are the same as those of the guide pipe 4, the protection pipe 3 can smoothly enter the guide pipe 4, and the connection between the fixing disc groove 32 and the guide pipe 1 is ensured.
Further, the diameter of the protecting tube fixing disc 31 is larger than that of the catheter 1, and two fixing disc grooves 32 are respectively arranged at the upper and lower positions with the same diameter as that of the catheter 1, and the two fixing disc grooves 32 are anastomosed with the proximal opening of the catheter 1 for fixing the catheter 1 and the protecting tube 3, so that the positioning is more accurate and the displacement is not easy.
Further, the lower edge of the protecting tube fixing disc 31 is provided with a protecting tube fixing disc lower edge magnetic attraction device 36 which can magnetically attract the catheter proximal end hand-held handle magnetic attraction device 35 on the hand-held handle 13, so that the catheter 1 and the protecting tube 3 can be better fixed.
Further, a fixed disc direction mark 33 and a fixed disc scale 34 are arranged on the surface of the fixed disc 31 of the protection tube, the fixed disc reverse mark 33 is used for defining the direction, and the fixed disc scale 34 is used for indicating the distance from the orifice of the protection tube 3.
Further, the length of the sampling rod 2 is at least 2-3cm longer than that of the catheter 1, and the sampling rod can penetrate through the protection tube 3 and enter the human body for sampling.
Further, the sampling brush material is a fiber soft brush for sampling, the fiber soft brush is a bendable material, the fiber soft brush is bent when the sampling rod 2 is inserted into the protection tube 3, and the fiber soft brush automatically resets when the sampling rod 2 exceeds the distal ends of the protection tube 3 and the guide tube 1, so that better sampling is achieved.
Further, a catheter proximal handle 13 is included, the catheter proximal handle 13 being located at the proximal end of the catheter 1 to assist in handling and positioning the catheter 1 for ease of fixation.
Further, a magnetic attraction device is arranged below the catheter proximal end handheld handle 13 and can magnetically attract the magnetic attraction device at the lower edge of the protective tube fixing disc, so that the catheter 1 and the protective tube 3 can be better fixed.
The invention also provides a use method of the device for positioning and sampling tissues in and around the cavity, which comprises the following steps:
1. the patient takes the lithotomy position, evenly coats the lubricating protective agent 4 outside the catheter 1, inserts the protective tube 3 into the catheter 1 and is positioned at the groove 32 of the fixed disc, and simultaneously the magnetic attraction device 35 of the proximal handheld handle of the catheter and the magnetic attraction device 36 at the lower edge of the fixed disc of the protective tube are mutually and magnetically attracted and fixed;
2. inserting the sampling rod 2 into the protective tube 3 to the distal opening 11 of the catheter (the sampling brush 21 of the sampling rod does not exceed the distal opening 11 of the catheter) and fixing;
3. the catheter 1, the protection tube 3 and the sampling brush 2 are inserted into the cavity together, and the sampling rod 2 is advanced by 1cm while the catheter 1 and the protection tube 3 are fixed;
4. at this time, the sampling brush 21 at the distal end of the sampling rod 2 is automatically reset, and the contact between the sampling brush 21 and the mucous membrane in the cavity is increased by rotating the sampling rod 2, so that the sampling success rate is improved;
5. the sampling brush 21 is retracted into the protective tube 3 after sampling, and the protective tube 3 and the sampling rod 2 are retracted out of the guide tube 1 together;
6. after the protective tube 3 and the sampling rod 2 are withdrawn from the catheter 1, the catheter 1 is advanced by 1cm, and then the completely new sampling rod 2 and the protective tube 3 are inserted into the catheter 1 and fixed in place, and sampling is continued according to the above method.
7. If the sampling involves the sampling of the parts such as the anorectum, the vagina, the cervical canal and the like, the device with corresponding specification can be taken, and the parts such as the anorectum, the urethra and the like are sampled according to the steps;
8. after the catheter 1 and the protective tube 3 are sent into the anus or the urethra, the protective tube fixing disc 31 is attached to the periphery of the anus or the coronary sulcus and glans penis, the azimuth and the scales of lesions are directly seen through the transparent protective tube fixing disc, the fixing disc azimuth mark 33 and the fixing disc scales 34 on the protective tube fixing disc 31 are read, the data of the fixing disc azimuth mark 33 and the fixing disc scales 34 are recorded, and the lesion part is clear;
9. and during the later review, sampling and review are performed according to the parts and the recorded data.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. The device for positioning and sampling tissues in and around a cavity comprises a catheter (1), a sampling rod (2), a sampling brush (21), a protection tube (3) and a protection tube fixing disc (31); the catheter (1) is a hollow catheter with two open ends, catheter graduations (5) are arranged on the outer side surface of the catheter (1), the sampling rod (2) penetrates through the protection tube fixing disc (31) to be inserted into the protection tube (3), the sampling brush (21) is arranged at the far end of the sampling rod (2), the protection tube (3) is inserted into the catheter (1), and the protection tube fixing disc (31) is arranged at the proximal end of the protection tube (3) and is fixedly connected with the protection catheter (1).
2. The device for positioning and sampling tissue in and around a cavity according to claim 1, wherein the catheter (1) is made of medical polycarbonate or polyether-ether-ketone plastic.
3. A device for positioning and sampling tissue in and around a lumen according to claim 1, wherein the catheter (1) is externally coated with a lubricant protective agent (4), the lubricant protective agent (4) being an ointment base.
4. The device for positioning and sampling tissues in and around a cavity according to claim 1, wherein the pipe diameter of the part of the protecting pipe (3) inserted into the catheter (1) is smaller than the pipe diameter of the catheter (1), and the length of the protecting pipe is the same as the length of the catheter (1).
5. A device for positioning and sampling tissue in and around a lumen according to claim 1, wherein the diameter of the protective tube fixing plate (31) is larger than that of the catheter (1), and a fixing plate groove (32) is arranged at the same position as that of the catheter (1), and the fixing plate groove (32) is matched with the proximal opening of the catheter (1) for fixing the catheter (1) and the protective tube (3).
6. The device for positioning and sampling tissues in and around a cavity according to claim 1 or 5, wherein the lower edge of the protective tube fixing disc (31) is provided with a protective tube fixing disc lower edge magnetic attraction device (36) which can magnetically attract a catheter proximal hand-held handle magnetic attraction device (35) on the hand-held handle (13), and better fix the catheter (1) and the protective tube (3).
7. A device for locating and sampling tissue in and around a cavity according to claim 1 or 5, wherein the surface of the protective tube fixing disc (31) is provided with a fixing disc direction mark (33) and a fixing disc scale (34).
8. A device for positioning and sampling tissue in and around a lumen according to claim 1, characterized in that the sampling rod (2) is at least 2-3cm longer than the catheter (1).
9. A device for positioning and sampling tissue in and around a lumen according to claim 1, wherein the sampling brush (21) is a fiber soft brush.
10. A device for positioning and sampling tissue in and around a lumen according to claim 1, further comprising a proximal handle (13) of the catheter, the proximal handle (13) of the catheter being fixedly connected to the proximal end of the catheter (1) for facilitating the fixation of the catheter (1) after handling and positioning.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311715283.3A CN117653218A (en) | 2023-12-14 | 2023-12-14 | Device for positioning and sampling tissues in and around cavity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311715283.3A CN117653218A (en) | 2023-12-14 | 2023-12-14 | Device for positioning and sampling tissues in and around cavity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117653218A true CN117653218A (en) | 2024-03-08 |
Family
ID=90080678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311715283.3A Pending CN117653218A (en) | 2023-12-14 | 2023-12-14 | Device for positioning and sampling tissues in and around cavity |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN117653218A (en) |
-
2023
- 2023-12-14 CN CN202311715283.3A patent/CN117653218A/en active Pending
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