CN117625392A - Biological sample transfer culture device - Google Patents

Biological sample transfer culture device Download PDF

Info

Publication number
CN117625392A
CN117625392A CN202311673170.1A CN202311673170A CN117625392A CN 117625392 A CN117625392 A CN 117625392A CN 202311673170 A CN202311673170 A CN 202311673170A CN 117625392 A CN117625392 A CN 117625392A
Authority
CN
China
Prior art keywords
biological sample
placement
transfer
sample transfer
culture device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202311673170.1A
Other languages
Chinese (zh)
Inventor
吴克良
李�城
陈子江
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandong University
Original Assignee
Shandong University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shandong University filed Critical Shandong University
Priority to CN202311673170.1A priority Critical patent/CN117625392A/en
Publication of CN117625392A publication Critical patent/CN117625392A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/52Mobile; Means for transporting the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/38Caps; Covers; Plugs; Pouring means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention provides a biological sample transfer culture device, and belongs to the technical field of biological sample experimental equipment. The biological sample transfer culture device comprises a transmission part, wherein the transmission part comprises a conveying device and a plurality of placement ports, and is configured to convey the biological sample placed at one of the placement ports to the other placement port by using the conveying device based on information of the biological sample in the culture dish. The biological sample transfer culture device can solve the problem of information correspondence error easily occurring in the transfer and handover process of biological samples in the related technology, and avoid medical accidents.

Description

Biological sample transfer culture device
Technical Field
The invention belongs to the technical field of biological sample experimental equipment, and particularly relates to a biological sample transfer culture device.
Background
In the surgical procedure of assisted reproductive medicine, it is often involved to take the egg cells of a patient in an operating room and then transfer the obtained egg cells to an embryo laboratory for fertilization and culture. After the embryo laboratory finishes culturing and fertilization, the embryo of the patient is transferred into an operating room for embryo transfer for conception.
In the related art, a window for embryo transfer is generally provided between an operating room and an embryo laboratory. After the operating room personnel obtain the ovum, the culture dish with the label is placed at the window, and after the embryo laboratory personnel obtain the culture dish, the embryo laboratory personnel correspondingly carry out the follow-up procedures of embryo development and artificial insemination according to the label information.
By adopting the transfer mode in the related art, the egg cell culture dish needs embryo laboratory personnel to manually take and confirm information in the transfer process. Because personnel in operating room and embryo laboratory are affiliated to different departments and teams, often there is time difference between the depositing and taking flow of embryo, and the in-process that embryo laboratory personnel took also has because of the human factor leads to the egg cell culture dish of taking to appear the wrong problem of matching with the culture dish of conception that waits to cultivate, especially when the window department deposited the egg cell culture dish of many patients, the risk that patient's ovum information had the mistake in the handing-over process is bigger, and then leads to embryo information to correspond the mistake and cause serious medical malpractice.
Disclosure of Invention
The embodiment of the invention provides a biological sample transfer culture device, which can solve the problem of information correspondence error easily occurring in the transfer and handover process of biological samples in the related technology and avoid medical accidents. The technical proposal is as follows:
the embodiment of the invention provides a biological sample transfer culture device, which comprises: a transmission part, a transmission part and a transmission part,
the transmission part comprises a conveying device and a plurality of placement ports, an information identification system is arranged at each placement port, and the transmission part is configured to identify the information of the biological sample in the culture dish through the information identification system so as to convey the biological sample placed at one placement port to the other corresponding placement port by using the conveying device.
Optionally, the transmission portion is configured to be in an inoperable state when the biological sample is delivered to the corresponding placement port.
Optionally, an information identification system is provided at each of the placement ports, the information identification system being configured to identify information of the biological sample.
Optionally, the information identification system is a tag identification system, and is used for identifying a number, a one-dimensional code, a two-dimensional code or an RFID.
Optionally, the transmission part includes a first placement port and a second placement port respectively disposed in two spaces isolated from each other.
Optionally, the conveying device is disc-shaped and is rotatably arranged in the conveying part along the axial direction, and a plurality of placement cabins matched with the placement ports are circumferentially arranged on the conveying device.
Optionally, the placing cabin comprises a placing cavity and a cover plate, and the cover plate sealing cover is arranged on the placing cavity.
Optionally, the biological sample transfer culture device further comprises a temperature control device, a heating plate is arranged in the placement cabin, and the temperature control device is electrically connected with the heating plate.
Optionally, the biological sample transfer culture device further comprises an air supply control device, an air supply air channel is arranged in the placement cabin, and the air supply control device is communicated with the air supply air channel.
Optionally, the transmission part is provided with a plurality of placement ports on the transmission part in a staggered manner.
Optionally, the biological sample transfer culture device further comprises a control panel, and the control panel is electrically connected with a plurality of the transmission parts.
Optionally, the biological sample transfer culture device further comprises a sealing cover, and the sealing cover is openably and closably arranged on the placement port.
Optionally, the biological sample transfer culture device further includes a status indicator light, the status indicator light is disposed beside the transmission portion, and the status indicator light outputs a plurality of optical signals based on the conveying status of the biological sample at the plurality of placement ports.
The technical scheme provided by the embodiment of the invention has the beneficial effects that at least:
with the biological sample transfer culture device, different placement ports are arranged on the transmission part to correspond to different positions where the biological sample is required to be transferred. The culture dish with biological samples is accurately conveyed to one of the placement ports to be conveyed by the conveying device after matching by the upper control host. The staff at the other side can accurately acquire the needed biological sample to carry out subsequent embryo development and artificial insemination processes, and can accurately convey the culture dishes to the staff carrying out embryo transplantation operation one by using the same operation after the biological sample is cultured, so that the error risk caused by manual and manual handover is avoided. The problem that information corresponding errors easily occur in the transfer and handover process of biological cell biological samples in the related technology can be effectively solved, and medical accidents are avoided.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments will be briefly described below, and it is apparent that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic perspective view of a biological sample transfer culture device according to an embodiment of the present invention;
FIG. 2 is a top structural view of a biological sample transfer culture device according to an embodiment of the present invention;
fig. 3 is a bottom view of a three-dimensional structure of a conveying device according to an embodiment of the present invention;
fig. 4 is a schematic partial structure of a transmission part in an operable state according to an embodiment of the present invention;
fig. 5 is a schematic view showing a partial structure of a transmission part in an inoperable state according to an embodiment of the present invention;
FIG. 6 is a block diagram showing a local control structure of a biological sample transfer and culture device according to an embodiment of the present invention.
In the figure:
1-a transmission part; 2-a temperature control device; 3-an air supply control device; 4-a control panel; 5-a status indicator light; 11-a conveying device; 12-placing ports; 12 a-a first placement port; 12 b-a second placement port; 13-sealing the cover; 111-placing a cabin; 121-an information recognition system; 1111-a placement chamber; 1112-cover plate; 1113-heating plate; 1114-gas supply path; a-operating room; b-embryo laboratory.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the present invention more apparent, the embodiments of the present invention will be described in further detail with reference to the accompanying drawings.
In the related art, a window for embryo transfer is generally provided between an operating room and an embryo laboratory. After the operating room personnel obtain the ovum, the culture dish with the label is placed at the window, and after the embryo laboratory personnel obtain the culture dish, the embryo laboratory personnel correspondingly carry out the follow-up procedures of embryo development and artificial insemination according to the label information.
By adopting the transfer mode in the related art, the egg cell culture dish needs embryo laboratory personnel to manually take and confirm information in the transfer process. Because personnel in operating room and embryo laboratory are affiliated to different departments and teams, often there is time difference between the depositing and taking flow of embryo, and the in-process that embryo laboratory personnel took also has because of the human factor leads to the egg cell culture dish of taking to appear the wrong problem of matching with the culture dish of conception that waits to cultivate, especially when the window department deposited the egg cell culture dish of many patients, the risk that patient's ovum information had the mistake in the handing-over process is bigger, and then leads to embryo information to correspond the mistake and cause serious medical malpractice.
Fig. 1 is a schematic perspective view of a biological sample transfer culture device according to an embodiment of the present invention. Fig. 2 is a top view of a biological sample transfer culture device according to an embodiment of the invention. Fig. 3 is a bottom view of a three-dimensional structure of a conveying device according to an embodiment of the present invention. Fig. 4 is a schematic partial structure of a transmission part in an operable state according to an embodiment of the present invention. Fig. 5 is a schematic partial structure of a transmission part in an inoperable state according to an embodiment of the present invention. FIG. 6 is a block diagram showing a local control structure of a biological sample transfer and culture device according to an embodiment of the present invention. As shown in fig. 1 to 6, the applicant provides a biological sample transfer culture device by practice.
Wherein the biological sample transfer culture device comprises a transmission part 1, and the transmission part 1 comprises a conveying device 11 and a plurality of placement ports 12. An information recognition system 121 is provided at each of the placement ports 12, and the transmission section 1 is configured to recognize information of the biological sample in the culture dish by the information recognition system 121 to convey the biological sample placed at one of the placement ports 12 to the corresponding other of the placement ports 12 by the conveying device 11.
In the embodiment of the present invention, the transmission part 1 of the biological sample transfer culture device can be installed between different spaces isolated from each other, and the corresponding placement port 12 can be arranged on the transmission part 1 for the different spaces. In the embodiment of the present invention, for the separated operating room a and embryo laboratory b, the transmission part 1 may be embedded in a wall body installed between the operating room a and embryo laboratory b instead of the conventional window design. For taking and placing the embryo culture dish, a first placing port 12a and a second placing port 12b are respectively arranged at the parts of the transmission part 1 positioned at the two sides of the operating room a and the embryo laboratory b. In use, a worker in the operating room a stores the egg cells in a culture dish after taking the egg cells, and attaches a label including information corresponding to the egg cells to the culture dish. The label contains various information, including at least information of the person to whom the embryo cells belong and information of operators. Then, the staff in the operating room a puts the culture dish into the first placing port 12a, scans the tag information through the information identification system 121 at the first placing port 12a, and synchronously uploads the data in the tag information to the upper control host for recording. The host control unit can locate the position to which the culture dish needs to be transmitted based on the data in the tag information, including but not limited to using a preset computer program, or manually performing orientation operation in the host computer. Control instructions can then be sent to the transfer device 11 based on the tag information, and the culture dish located at the first placement port 12a can be transferred to the second placement port 12b located in the embryo laboratory b by means of the transfer device 11. The staff in embryo laboratory b can accurately pick up the procedure of embryo development and artificial insemination which needs to be carried out later. After embryo culture is completed, the fertilized egg culture dish which is completed to culture fertilized can be accurately conveyed back to the operating room a by the transmission part 1 through the reverse operation of the same flow, and the artificial conception operation is performed.
With this biological sample transfer culture apparatus, different placement ports 12 are provided in the transfer section 1 to correspond to different positions where the biological sample is to be transferred. By correspondingly arranging the information identification system 121 at each placement port 12, the label information on the culture dish with the biological sample can be scanned and data uploaded before transmission, and after matching by using an upper control host, the culture dish placed at one placement port 12 is accurately conveyed to the other placement port 12 to be conveyed by using the conveying device 11. The staff at the other side can accurately acquire the needed biological sample to carry out subsequent embryo development and artificial insemination processes, and can accurately convey the culture dishes to the staff carrying out embryo transplantation operation one by using the same operation after the biological sample is cultured, so that the error risk caused by manual and manual handover is avoided. The problem of information correspondence error easily occurring in the transfer and handover process of biological samples in the related technology can be effectively solved, and medical accidents are avoided.
Alternatively, in the embodiment of the present invention, the information identifying system 121 is a tag identifying system for identifying a tag attached to a culture dish, such as a number, a one-dimensional code, a two-dimensional code, or an RFID.
Alternatively, the transmission section 1 is configured such that when a biological sample is transported to the corresponding placement port 12, the other placement ports 12 of the plurality of placement ports 12 are in an inoperable state. For example, referring to fig. 4 and fig. 5, in the embodiment of the present invention, when a biological sample is transported to the placement port 12 corresponding to the prepared taking-out position, the placement ports 12 remaining at other positions of the transport portion 1 are all switched to an inoperable state under the control of the upper control host, including but not limited to closing the placement port 12, or locking the transport device 11 to allow the transport device 11 to fill the placement port 12 in a position where the culture dish cannot be placed, so that the remaining placement ports 12 cannot take out and place the culture dish, thereby ensuring that only the placement port 12 at the prepared taking-out position is in an opened operable state in this state, and enabling the working position at the corresponding position to accurately take out the biological sample corresponding to the label information, thereby further improving the transfer stability.
Optionally, the conveying device 11 is disc-shaped and is rotatably arranged in the conveying part 1 along the axial direction, and a plurality of placement cabins 111 matched with the placement ports 12 are circumferentially arranged on the conveying device 11. Illustratively, in the embodiment of the present invention, the transmission part 1 is disc-shaped and embedded in a wall between the operating room a and the embryo laboratory b, and the transmission part 1 is protruded from the wall of the operating room a and the embryo laboratory b, and the transmission device 11 is also disc-shaped and coaxially rotatably disposed in the transmission part 1. The disc-shaped conveying device 11 is provided with the placing cabin 111 which corresponds to the mounting of the culture dishes, the size of the placing cabin 111 is matched with the opening size of the placing port 12, when the culture dishes are taken and placed by utilizing the first placing port 12a or the second placing port 12b, the placing cabin 111 can only be used for taking and placing single biological samples one by one, taking and placing errors are avoided, and the transfer accuracy of the biological sample transfer culture device is further improved.
Illustratively, in the embodiment of the present invention, a plurality of placement bins 111 matched with the placement ports 12 are circumferentially arranged on the conveying device 11, and when a plurality of embryo culture dishes need to be conveyed at the same time, a plurality of culture dishes can be placed in the plurality of placement bins 111 after being scanned by the label information, so that stacking is avoided. In the conveying process of one of the culture dishes, before the culture dish to be taken away by the placement port 12a is not taken away, other culture dishes can be temporarily stored in the transmission part 1 and cannot be exposed at the placement port 12a, so that a taking and placing error is avoided. When the culture dish to be taken exposed from the placement port 12a is taken away, other culture dishes are driven by signals of the upper control host, so that the placement cabin 111 placed by the culture dish is rotated to the corresponding placement port 12a for standby for subsequent taking and placing.
Optionally, the placement chamber 111 includes a placement chamber 1111 and a cover plate 1112, the cover plate 1112 sealing the cover 13 over the placement chamber 1111. In the embodiment of the present invention, each placing compartment 111 is configured as an open-close sealed compartment structure composed of a placing chamber 1111 at the lower part and an openable cover plate 1112, and is unlocked only when the placing compartment 111 rotates to the accurate placing port 12a under the control of a signal of an upper control host, and is automatically opened or allowed to be manually opened under the control of an electric control device, so as to achieve the corresponding taking and placing of the culture dishes, and further improve the transfer accuracy of the biological sample transfer culture device. Meanwhile, the sealed storage environment can also seal and isolate the culture dish from the external environment, so that the influence of different temperature and humidity environments between the operating room a and the embryo laboratory b on biological samples in the process of transferring and storing to be taken and placed is reduced, and the activity of the biological samples is ensured.
Illustratively, in the embodiment of the present invention, when one of the placement modules 111 rotates to the corresponding placement port 12a following the conveyor 11, it can be unlocked under the control of the upper control host, so as to achieve the removal of the culture dish. At this time, the other placing cabins 111 circumferentially arranged on the conveying device 11 are all in a closed and locked state and cannot be opened, so that even if the placing cabins 111 are in a state corresponding to the other placing ports 12a, workers in working positions at other positions cannot open the placing cabins 111 to cause misoperation.
Optionally, the biological sample transfer culture device further comprises a temperature control device 2, a heating plate 1113 is arranged in the placing cabin 111, and the temperature control device 2 is electrically connected with the heating plate 1113. Illustratively, in the embodiment of the present invention, the upper control host is integrated with the temperature control device 2, which can correspondingly control the heating plate 1113 disposed in the placement cabin 111 according to the label information of the biological sample to realize dimension adjustment, so that the temperature in the placement cabin 111 reaches a constant temperature level required for maintaining the biological sample to be cultured and developed, and the activity of the biological sample in the process of transferring and storing the biological sample is ensured.
Illustratively, in the embodiment of the present invention, in addition to the heating plate 1113 disposed in the placement chamber 1111 of the placement chamber 111, a heating plate 1113 (not shown in the drawing) may be disposed correspondingly inside the cover plate 1112 to achieve overall heating in the placement chamber 111 and improve temperature uniformity at various locations in the placement chamber 111.
Optionally, the biological sample transfer culture device further comprises an air supply control device 3, an air supply air channel 1114 is arranged in the placing cabin 111, and the air supply control device 3 is communicated with the air supply air channel 1114. Illustratively, in the embodiment of the invention, the upper control host is integrated with the air supply control device 3, so that the air supply air channel 1114 arranged in the placing cabin 111 can be controlled according to the label information of the biological sample, and the air with the specified composition and concentration is introduced into the placing cabin 111 through the opening of the air supply air channel 1114, so that the constant concentration level of the air required by the maintenance culture and development of the biological sample is maintained, and the activity of the biological sample in the process of taking and placing the transfer and storage belt is ensured.
Optionally, the transmission part 1 is provided with a plurality of placement ports 12 on the plurality of transmission parts 1 are arranged in a staggered manner. In the embodiment of the invention, a plurality of disc-shaped transmission parts 1 are coaxially arranged along the longitudinal direction, so that the simultaneous transfer of a plurality of biological samples can be realized, and meanwhile, the transfer efficiency is improved while the occupied working space is reduced and the transfer accuracy is ensured based on the working mechanism of placing and taking embryo label information. And, through carrying out dislocation arrangement based on the axis position with the port 12 of placing that is located on the different transmission parts 1 of same space side in circumference, can avoid placing port 12 and be in same vertical space, make things convenient for the staff to take, further improved biological sample and shifted the practicality of culture apparatus.
Illustratively, in the embodiment of the present invention, 1 to 33 placement modules 111 may be provided on the disc body of the disc-shaped conveying device 11 in each conveying section 1, to adapt to the transfer environments of different sizes and demands.
Optionally, the biological sample transfer culture device further includes a control panel 4, and the control panel 4 is electrically connected to the plurality of transmission parts 1. For example, in the embodiment of the present invention, the biological sample transfer culture device may be provided with a control panel 4, such as a touch panel with integrated display operation, at the end of which the state of the transmission part 1 can be observed and controlled, corresponding to the host control computer. The control panel 4 can control the start and stop of the transmission part 1 and observe and confirm the contents contained in the label information of the conveyed biological samples on the working states of the plurality of transmission parts 1, so that the transfer accuracy of the biological sample transfer culture device is further improved.
Optionally, the biological sample transfer culture device further comprises a sealing cover 13, and the sealing cover 13 is openably and closably arranged on the placement port 12. In the embodiment of the present invention, a layer of sealing cover 13 is slidably sleeved inside each placement port 12, and when the corresponding placement port 12 is not used or is in an inoperable state, the sealing cover 13 can extend under the drive of the upper control host and seal the placement port 12, so as to seal and isolate the internal conveying device 11, ensure the stability of the internal storage environment, and avoid the misoperation of taking and placing by staff.
Optionally, the biological sample transfer culture device further includes a status indicator light 5, where the status indicator light 5 is disposed beside the transmission portion 1, and the status indicator light 5 outputs multiple optical signals based on the conveying status of the biological sample at the multiple placement ports 12. Illustratively, in the embodiment of the present invention, the running state of the transfer culture device can be displayed by setting the status indicator lamp 5, and the status lamp is turned on green when the conveying device 11 rotates the designated placing cabin 111 into place to the formulated placing port 12 according to the interactive operation instruction; when the conveying device 11 is in the process of movement, the status light is lighted red; when the conveying device 11 is in the standby state, the status light is lighted blue; for alerting the user to the mechanical rotation structure of the device and the status of the operational pod 111.
Unless defined otherwise, technical or scientific terms used herein should be given the ordinary meaning as understood by one of ordinary skill in the art to which this invention belongs. The terms "first," "second," and the like in the description and in the claims, are not used for any order, quantity, or importance, but are used for distinguishing between different elements. Likewise, the terms "a" or "an" and the like do not denote a limitation of quantity, but rather denote the presence of at least one. The word "comprising" or "comprises", and the like, means that elements or items appearing before "comprising" or "comprising" are intended to be inclusive of the elements or items listed thereafter as "comprising" or "comprising", and not to exclude other elements or items. The terms "connected" or "connected," and the like, are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "upper", "lower", "left", "right", etc. are used merely to denote relative positional relationships, which may also change accordingly when the absolute position of the object to be described changes.
The foregoing description of the preferred embodiments of the present invention is not intended to limit the invention, but rather, the invention is to be construed as limited to the appended claims.

Claims (13)

1. A biological sample transfer culture device, comprising: a transmission unit (1),
the transfer part (1) comprises a conveying device (11) and a plurality of placement ports (12), and the transfer part (1) is configured to convey the biological sample placed at one of the placement ports (12) to the corresponding other one of the placement ports (12) by using the conveying device (11) based on information of the biological sample in the culture dish.
2. The biological sample transfer culture device according to claim 1, wherein the transfer section (1) is configured such that when the biological sample is transferred to the corresponding placement port (12), the other placement ports (12) of the plurality of placement ports (12) are in an inoperable state.
3. The biological sample transfer and culture device according to claim 1, wherein an information identification system (121) is provided at each of the placement ports (12), the information identification system (121) being adapted to identify information of the biological sample.
4. A biological sample transfer and culture device according to claim 3, wherein the information identification system (121) is a tag identification system for identifying a number, a one-dimensional code, a two-dimensional code or an RFID.
5. The biological sample transfer culture apparatus according to claim 1, wherein the transfer section (1) includes a first placement port (12 a) and a second placement port (12 b) respectively provided in two spaces isolated from each other.
6. The biological sample transfer and culture device according to claim 5, wherein the conveying device (11) is disc-shaped and is rotatably arranged in the conveying part (1) along the axial direction, and a plurality of placing cabins (111) matched with the placing ports (12) are circumferentially arranged on the conveying device (11).
7. The biological sample transfer and culturing device according to claim 6, wherein the placement chamber (111) comprises a placement chamber (1111) and a cover plate (1112), and the cover plate (1112) seals the cover (13) on the placement chamber (1111).
8. The biological sample transfer and culture device according to claim 6, further comprising a temperature control device (2), wherein a heating plate (1113) is arranged in the placement chamber (111), and the temperature control device (2) is electrically connected with the heating plate (1113).
9. The biological sample transfer and culture device according to claim 6, further comprising an air supply control device (3), wherein an air supply air channel (1114) is arranged in the placement chamber (111), and the air supply control device (3) is communicated with the air supply air channel (1114).
10. The biological sample transfer and culture device according to claim 5, wherein the plurality of the transmission parts (1) are arranged, and the placement ports (12) on the plurality of the transmission parts (1) are arranged in a staggered manner.
11. The biological sample transfer and culture device according to claim 10, further comprising a control panel (4), wherein the control panel (4) is electrically connected to a plurality of the transfer sections (1).
12. The biological sample transfer culture device according to any one of claims 1 to 11, further comprising a sealing cover (13), the sealing cover (13) being openably and closably covered to the placement port (12).
13. The biological sample transfer culture device according to any one of claims 1 to 11, further comprising a status indicator light (5), the status indicator light (5) being disposed beside the transmission section (1), the status indicator light (5) outputting a plurality of optical signals based on a transport status of the biological sample at the plurality of placement ports (12).
CN202311673170.1A 2023-12-07 2023-12-07 Biological sample transfer culture device Pending CN117625392A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311673170.1A CN117625392A (en) 2023-12-07 2023-12-07 Biological sample transfer culture device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202311673170.1A CN117625392A (en) 2023-12-07 2023-12-07 Biological sample transfer culture device

Publications (1)

Publication Number Publication Date
CN117625392A true CN117625392A (en) 2024-03-01

Family

ID=90018090

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202311673170.1A Pending CN117625392A (en) 2023-12-07 2023-12-07 Biological sample transfer culture device

Country Status (1)

Country Link
CN (1) CN117625392A (en)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103013828A (en) * 2012-11-28 2013-04-03 中国科学院广州生物医药与健康研究院 Cell incubator capable of realizing intelligent identification and transmission
US20170009195A1 (en) * 2014-02-03 2017-01-12 Unisense Fertilitech A/S Incubator apparatus and methods
CN108434481A (en) * 2018-05-29 2018-08-24 吴江市净明净化设备有限公司 A kind of cellular-type pass-through box
CN208632561U (en) * 2018-05-29 2019-03-22 柳州市妇幼保健院 A kind of egg mother cell/embryo's transmitting window protective device
CN213330182U (en) * 2020-08-14 2021-06-01 山东凯景生物技术有限公司 Nucleic acid sampling cabin
CN213743032U (en) * 2020-08-20 2021-07-20 竟钢机电(天津)有限公司 Rotatable pass-through box of multilayer
CN114107054A (en) * 2021-12-16 2022-03-01 山东大学 Rotary culture device and method
CN117095180A (en) * 2023-09-01 2023-11-21 武汉互创联合科技有限公司 Embryo development stage prediction and quality assessment method based on stage identification
CN117229907A (en) * 2023-09-28 2023-12-15 武汉互创联合科技有限公司 Biological sample transfer culture system

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103013828A (en) * 2012-11-28 2013-04-03 中国科学院广州生物医药与健康研究院 Cell incubator capable of realizing intelligent identification and transmission
US20170009195A1 (en) * 2014-02-03 2017-01-12 Unisense Fertilitech A/S Incubator apparatus and methods
CN108434481A (en) * 2018-05-29 2018-08-24 吴江市净明净化设备有限公司 A kind of cellular-type pass-through box
CN208632561U (en) * 2018-05-29 2019-03-22 柳州市妇幼保健院 A kind of egg mother cell/embryo's transmitting window protective device
CN213330182U (en) * 2020-08-14 2021-06-01 山东凯景生物技术有限公司 Nucleic acid sampling cabin
CN213743032U (en) * 2020-08-20 2021-07-20 竟钢机电(天津)有限公司 Rotatable pass-through box of multilayer
CN114107054A (en) * 2021-12-16 2022-03-01 山东大学 Rotary culture device and method
CN117095180A (en) * 2023-09-01 2023-11-21 武汉互创联合科技有限公司 Embryo development stage prediction and quality assessment method based on stage identification
CN117229907A (en) * 2023-09-28 2023-12-15 武汉互创联合科技有限公司 Biological sample transfer culture system

Similar Documents

Publication Publication Date Title
US11885823B2 (en) System and method for incubation and reading of biological cultures
EP2604679B1 (en) Cell culture treatment system, and method for connection of modules for cell culture treatment system
US8616072B2 (en) System and methods for sampling materials
KR101873580B1 (en) System for producing cellular therapeutic agents
ES2397174T3 (en) Laboratory apparatus set with incubator
CN109661582A (en) Automatic cytological processing system and method
WO2021246410A1 (en) Inspection system
JP2022518102A (en) A system for processing biological materials with multiple uniform design storage modules
WO2009116271A1 (en) Container transportation case and culture treating device
CN117229907A (en) Biological sample transfer culture system
JP2022516832A (en) Module for automated biology laboratory system with interface for transporting microplates or labware
JP2022516833A (en) Labware and labware handling systems in cell culture processes
Naber Continuing role of a frozen-tissue bank in molecular pathology
US20090181449A1 (en) Device and method for automating microbiology processes
CN117625392A (en) Biological sample transfer culture device
JP2012147685A (en) Cell culture treatment system
EP4417976A1 (en) System for macromolecule extraction
JP2012147693A (en) Dispensation device and cell culture treatment system
US20220332525A1 (en) System for handling biological tissue samples
JP2007020411A (en) Automatic cell culture system
JP4274859B2 (en) Culture equipment and automatic culture equipment
RU2811721C1 (en) System for incubation and formation of digital images of biological samples
US20230112758A1 (en) Modular incubators for configurable workstations
RU2813445C1 (en) Chamber for incubation of biological samples
RU2812238C1 (en) Module for movement of containers in chamber for incubation of biological samples

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination