CN1176222A - On-site syringe filling apparatus for viscoelastic materials, and corresponding method for on-site syringe filling - Google Patents

On-site syringe filling apparatus for viscoelastic materials, and corresponding method for on-site syringe filling Download PDF

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Publication number
CN1176222A
CN1176222A CN 96122434 CN96122434A CN1176222A CN 1176222 A CN1176222 A CN 1176222A CN 96122434 CN96122434 CN 96122434 CN 96122434 A CN96122434 A CN 96122434A CN 1176222 A CN1176222 A CN 1176222A
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China
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syringe
visco
elastic material
pump
supply container
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CN 96122434
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Chinese (zh)
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F·R·克莱斯特
E·F·费希尔
K·E·卡齐欧斯卡斯
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A Legen
Allergan Inc
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A Legen
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Abstract

An automated, syringe filling apparatus is disclosed for the on-site filling of syringes with a viscoelastic fluid material from a supply reservoir. A housing has a port for receiving the outlet end region of the viscoelastic supply reservoir and a retainer is provided for releasably retaining a conventional syringe to be filled from the viscoelastic supply reservoir. A flexible plastic tube, preferably formed as part of the viscoelastic supply reservoir, is used to interconnect the supply reservoir with a filling end of a syringe retained in the syringe retainer. A peristaltic pump mounted in the housing has a rotating head with a plurality of rollers which force the viscoelastic material through the tube from the supply reservoir into a retained syringe when the tube is locked between the pump head and a back-up member. A corresponding method is disclosed for the on-site filling of a syringe with a viscoelastic fluid from a supply reservoir.

Description

The syringe in-site pouring device and the method for filling that are used for visco-elastic material
The present invention relates generally to medical instruments field, more specifically, relates to the surgical instruments field, more distinguishingly, relates to the relevant syringe of operation that is used for injecting with needs visco-elastic material.
The multiple operation that the patient is carried out requires (using syringe usually) to inject biocompatible visco-elastic material or " liquid " (that is high astringency liquid) of set amount, its purpose is to make responsive surrounding tissue to avoid unexpected, the injury that causes by operation, and/or, make it not be subjected to ongoing operating the influence in order to keep or to locate selected tissue.Usually to remove memory fluid after the operation, but in some cases, according to surgical judgement, if continue to stay in the patient body is favourable, if with material be biocompatible cmpd, for example, transparent acidic base materials, it can be absorbed or digest by human body under the condition that has no side effect, and then can stay in the body.
The operating representative type example of this class is, in a kind of operation, a spot of visoelasticity liquid injects patient's intraocular, in this operation, extract damaged or made the patient lose the crystalline lens of the trouble eye of eyesight.Be referred to as in the operating operation of crystalline lens this, be implanted in intraocular to the people crystal (being commonly referred to intraocular lens (IOL)) of faking, to recover patient's eyesight.IOL generally is implanted in original crystalline region ill or damage of having extractd.Typically, but optional, excision may be original crystal of the damage that caused by cataract and implant the IOL that substitutes and finish in performing the operation in same crystal.
In this crystal surgical procedures; usually to inject visco-elastic material with the syringe of a low dose patient's intraocular; so that protect the non-re-epithelialize cellular layer of the sensitivity of cornea effectively; it for example can be subjected to, by the contact of the accident of institute's use apparatus in operation and/or by the fragment of the original crystal that picked-off and/or when IOL implantation intraocular or when locating within the eye by the caused damage of IOL.In separating operation, also can inject visco-elastic material, so that prevent in surgical procedures owing to Vitrea loss causes subsiding of eye.
The most of visco-elastic materiaies that use in this crystalloid operation at present or " liquid " are that mol wt in suitable buffer solution is 500,000 to 2,000, high molecular weight hyaluronic acid between more than 000 (hyaluronic acid), because hyaluronic acid is present in the normal human eye naturally with low concentration, thereby it is a biocompatibility, it has the viscoelastic property of liquid, when measuring with traditional viscosity mensuration, it has about per second 40, the dynamic viscosity of 000cps usually.Representative type hyalomitome acidic group viscoelastic solution is respectively by the Allergan Co., Ltd, Kabi Pharmacia, and Alcon laboratory and Iolab company be VITRAX respectively R, HEALON R, VISCOAT RAnd AMVISC RPut on market.
Known to the inventor, the injectable medicinal fluid of low viscosity (for example, vaccine inoculation and microbiotic) offer the medical worker with the form that seals (little) bottle usually, before the liquid injection, from bottle, install in the syringe again, in contrast, the memory fluid of the above-mentioned type always in advance by visco-elastic material maker pack into the sterilization disposable syringe in.This is because up to the present, and memory fluid is thanked to astringency and made to be exactly visco-elastic material to be filled into be difficult to very much in the normally used syringe realize.
Yet, only there is " factory's perfusion " memory fluid in syringe can not satisfy many medical professionals' needs, owing to actual reason be at least owing to the operating reason of crystal, syringe all be usually by maker with about 0.4ml to one or both the most frequently used viscoelastic body dosage about 1.0ml in factory's perfusion.
Yet, can not pack into the usually visco-elastic material of accurate dosage of these syringes that pour into visco-elastic material in advance, and this dosage just the surgeon do want or the needed amount of an operation.For instance, if, it is 0.75ml that the surgeon determines for the required visco-elastic material of certain eye surgery, he (she) can only use the some in the 1.0ml syringe, visco-elastic material remaining in the syringe can only abandon, because it can not use another operation again for the reason on the patient safety.
A kind of possible alternative is that the sawbones uses several syringes.Each all is equipped with the visco-elastic material that is less than desired dosage, but meets desired dosage altogether.Yet, this alternative is normally unfavorable, because relate to two, or the extra spending of the viscoelastic body syringe of more a plurality of factories perfusion, this comprises about packing and other spending, and also may be because of requiring additional step and required " time within the eye " (time-in-the-eye).
Another kind of possible alternative is that the surgeon is satisfied with than he (she) and judges required visco-elastic material dosage still less, thereby the single syringe that can use the amount of contained visco-elastic material to lack than desired amount.Therefore repay examination although exist to be satisfied with than what the amount of desired visco-elastic material was lacked, can predict, most of surgeons can think that this alternative is that a kind of surgery that do not meet the specification or unsafe is repaid examination.
Therefore, the most common way is to abandon or discarded very a spot of visco-elastic material in many or most of eye surgeries.This way can not appear at those on the unfamiliar person of the medical reparations policy of the existing strictness that causes very big concern.Yet reality is that all costs relevant with operation all are to be carried out under the audit of strictness by the medical expense compensator, and any rejected material is considered to very undesirable at present at least.
Expense with respect to above-mentioned visco-elastic material waste, the expense of the viscoelastic injector of the factory of above-mentioned size perfusion is at present from being low to moderate the 20-30 dollar to up to 80 dollars, even 100 dollars scope, this depends on quality (reality or noticeable) to a great extent.High like this expense is that the production process by the costliness of the hyaluronic acid that requires to obtain highly purified sterilization (no matter being to be obtained by crest (rooster combs) or biofermentation) is determined.
Therefore, 1/4th of the visco-elastic material in the syringe of staying factory's perfusion that goes out of use constitutes from 7,8 dollars to nearly " loss " between 20 or 25 dollars.Based on single operation, consider the expense of whole eye surgery, as if this quantity is little, yet, only 1,700,000 routine cataract surgery just there is every year in the U.S., suppose that this operation of wherein having only half is 10 dollars of visco-elastic material losses, then the total loss that is caused by discarded visco-elastic material in cataract surgery reaches 8,500,000 dollars.This finally will be paid by the public.
For these and other tangible reason, comprise for convenience's sake and in order to reduce officina (office), the stock of factory's perfusion visco-elastic material syringe of clinic and hospital, the invention provides a kind of device that can on the spot the visco-elastic material in the material supply receiver be filled in the standard syringe, this device make according to the surgeon at the particular surgeries requirement maybe needs the visco-elastic material of exact dose be filled into become possibility in the syringe, and perfusion can be carried out before operation is about to begin.
According to the present invention, provide a kind of being used for that visco-elastic material is filled into syringe device for casting in the syringe.This device comprises a receiving port that is used to admit the mouth of visco-elastic material supply container, with one be used to admit and with discharge end (that is entry needle syringe needle attachment end) institute's injection clamper of the traditional injector for medical purpose of mode clamping that can extract, described syringe will be admitted the visco-elastic material in the supply container of visco-elastic material.This device also comprises and is used for admitting mouthful visco-elastic material of admitting from the visco-elastic material supply container to be sent to the discharge end of the syringe that clamping on the clamper at syringe and being sent to the syringe so that pour into the conveyer of this syringe from said discharge end.
According to a preferred embodiment of the present invention, this device also comprises a housing and a liquid transfer canal, Rou Ruan plastic pipe preferably, this pipe is contained in the housing, and the discharge end that is used for the syringe on mouth that will be contained in the visco-elastic material supply container of admitting mouthful and the clamper that is contained in syringe is connected with each other.
With being connected of the plastics conveyer conveyor trunk of this softness in, the visco-elastic material conveyer preferably includes a ram type pump with rotating pump head, a plurality of pump rollers that separate along circumference are housed on the said pump head, pump is mounted to makes pump head be contained in form in the housing at least.
A supporting member is contained in the housing near the pump head place, be used between open position and closing device, pivotally rotating, in described open position, the part of conveyer conveyor trunk can be between the some parts and pump head of supporting member, in described make position, operation by pump is rotated pump head, cause that the pump roller sequentially compresses on some positions between the supporting member that is in pump head and closes of conveyer conveyor trunk, make the visco-elastic material that is received in the viscoelastic material supply container of admitting mouthful in conveyer conveyor trunk pumps into syringe on the clamper that is clamped in syringe.
The ram type pump of electricity operation is connected on the external power, and in this case, this device comprises the electrical controller of the operation that is used for control pump.Electrical controller preferably can be used for the independently perfusion operation of primer pump, so that be filled in the conveyer conveyor trunk with regard to the visco-elastic material in the supply container that will be received in the visco-elastic material of admitting mouth earlier before in the clamper that syringe is installed in syringe.
In addition, electrical controller preferably includes an optionally liquid pump controller, for example, the pump calculagraph, have on this time meter and the relevant sign (calculagraph) of dosage that will from the visco-elastic material supply container that is contained in receiving port, be sent to the visco-elastic material in the syringe on the clamper that is installed in syringe by the liquid pump, thus, the visco-elastic material in the supply container can be filled in the syringe with predetermined dosage.
Electric controller preferably includes a syringe perfusion horizon sensor, when being perfused in predetermined level by visco-elastic material supply container perfusion syringe, this sensor can detect this information, and after this, even the pump calculagraph as yet not timing finish, also automatically cut off the liquid pump.
This device preferably includes a pressure device, and for example, an air pump is used for the pressurization of visco-elastic material supply container, so that guarantee not produce bubble in conveyer conveyor trunk when syringe perfusion operation.In this case, electric controller is used for control air pump when the liquid pump work.An oil release valve is preferably arranged, to prevent the container overvoltage on the visco-elastic material supply container.
The soft conveyer conveyor trunk preferably output end region place of the visco-elastic material supply container in being received into the admittance mouth is integrally formed.In this case, conveyer conveyor trunk is the some of container, and container is when empty after having poured into a plurality of syringes, and conveyer conveyor trunk abandons with container.
The present invention also provides the corresponding method that is used for pouring into visco-elastic material on the spot syringe, this method comprises the steps: to provide the supply container that the visco-elastic material that is used to pour into syringe is housed, the liquid conveyer conveyor trunk of the installation needle end of syringe by softness is connected on the mouth of container, and the flattening connection pipe, the visco-elastic material in the visco-elastic material supply container is flowed in the syringe by this pipe.The step of with visco-elastic material in supply container earlier pouring into conveyer conveyor trunk before this method is preferably incorporated in and is connected on the conveyer conveyor trunk to syringe, can also comprise step, so that in conveyer conveyor trunk and when syringe perfusion operation, in syringe, do not form bubble to the pressurization of visco-elastic material supply container.
In addition, method of the present invention also preferably includes the step that soft conveyer conveyor trunk is shaped with the visco-elastic material supply container, so that after pouring into a plurality of syringes, in visco-elastic material uses up, conveyer conveyor trunk is abandoned with supply container with the visco-elastic material in the supply container.Method of the present invention also further preferably is included in when being filled into the visco-elastic material in the supply container in the syringe, and syringe is remained on a fixing locational step with respect to the visco-elastic material supply container in removable mode.
According to a preferred embodiment, the step of flattening conveyer conveyor trunk, making visco-elastic material flow into syringe from the visco-elastic material supply container through conveyer conveyor trunk comprises with the ram type pump with pump head roller the step of visco-elastic material by the conveyer conveyor trunk pumping be its objective is when pump work conveyer conveyor trunk is comprehensively compressed.
In described method, also further comprise the work of control pump so that the visco-elastic material of scheduled volume can only be pumped into step in institute's bonded assembly syringe.
Therefore, the invention provides and be used on the spot the visco-elastic material of visco-elastic material supply container being filled into device and corresponding method in the syringe with predetermined dosage in the mode of control.
From the present invention may be better understood below in conjunction with the description of the drawings, accompanying drawing has:
Fig. 1 is the transparent view that is used for memory fluid is filled on the spot the device of syringe according to a preferred embodiment of the present invention, housing with the admittance mouth that is used for admitting disposable visco-elastic material supply container shown in the figure and one be used for one of removable mode clamping common disposable, by the syringe clamper of the syringe of visco-elastic material supply container perfusion.Also further illustrate among the figure and be used for the device of visco-elastic material supply container pressurization and the some parts of memory fluid transfer pump.
Fig. 2 is the part cutaway view of the leading flank of the housing among Fig. 1, shows the inside and the visco-elastic material pump part of device;
Fig. 3 is the part transverse sectional view along the 3-3 hatching among Fig. 2, shows the extention of visco-elastic material pump;
Fig. 4 is the transverse sectional view along the 4-4 line among Fig. 1, shows the member of syringe clamper;
Fig. 5 is the automatically controlled part figure of device.
Components identical marks with identical label with parts among above-mentioned each figure.
Shown in Figure 1 is a kind of automatic or active syringe device for casting 10, and it is a kind of special structure, is used for by visco-elastic material (as VITRAX R, HEALON ROr AMVISC R) source or supply container 14 pour into conventional injector for medical purpose 12 on the spot.Should be appreciated that term " on the spot " is a broad sense as used herein, means doctor office, Health Service Laboratory or clinic, surgery or operating room, hospital or similar department, they normally patient to be ready standing maybe can stand to use the operating place of visco-elastic material at this.Certainly, device 10 might as well be used for small-sized visoelasticity material manufacturing equipment.
Device 10 comprises a housing 16, this housing has a downward opening 18 that is used for admitting at least the bottom 20 of visco-elastic material supply container 14, described container 14 is passable, for example (never means restriction or hint), and 50 to 100ml visco-elastic material 22 is housed.With spaced apart being installed to of the admittance mouth 18 of visco-elastic material supply container be a syringe clamper 30 on the housing 16, be used for when syringe perfusion operation with removable mode clamping syringe 12.This syringe 12, it preferably has the size of the disposable syringe of factory's perfusion visco-elastic material, and it can adorn about 1ml liquid, and growing up is about 5-10cm, and external diameter is approximately 0.5-1.0cm.
As shown in Figure 1 and Figure 4, syringe clamper 30 comprises halfpipe spare 32, its size is convenient to admit by its open side the syringe part 34 of syringe 12, also has shoulder 36 for said 32, its size is suitable for admitting the finger grips part 38 of syringe, releasable syringe locking folder 40 pivotally is connected to the side regions of part 32, so that pass the open side of part 32 and thus syringe 12 be clamped on the syringe holding frame 30 so that from the perfusion syringe up to by draw back earlier folder take off again the syringe that poured into during this period of time in opposing perfusion power firmly.
Device 10 comprises memory fluid conveyer 50, is used for the visco-elastic material that is received in the supply container 14 of admitting mouth 20 is sent in the syringe 12 that is clamped in the syringe clamper 30 (seeing Fig. 1 and Fig. 2).What constitute (Comprising) memory fluid conveyer 50 is a flexible plastic pipe 52 that is used to pour into operation, and it is connected between the syringe needle installation end 56 of syringe 12 of the discharge end 54 below the supply container 14.Also comprise a liquid pump 60 (Fig. 1-3) in the conveyer, it is positioned at housing 12, and is between the admittance mouth 14 and syringe clamper 30 of supply container.
Preferably, also just as shown in FIG. 3, liquid pump 60 is ram type pumps, and it has an electrical motor 62 and one and is connected to the head assembly 64 that drives rotationally on the electrical motor by rotating shaft 66.Head assembly 64 comprises a cheese head 68, has on 68 a plurality of by pivotally being contained in pump roller 70 (Fig. 2) on the peripheral portions in relation spaced apart from each other on the circumference each other.As shown in the figure, four such pump rollers 70 are installed with 90 ° interval around pump head 68.
One end of the supporting member 72 of a L-shaped generally rigidity pivotally is installed in the housing 16 near pump head assembly 64 places (Fig. 1 and Fig. 2) by a pivot pin 74, supporting member 72 around pin 74 between make position (Fig. 1 and by shown in the solid line among Fig. 2) and open position (shown in the long and short dash line among Fig. 2) under manual operation pivoted.Because the formation of part 72 and the installation by pivot pin 74, therefore, when part 72 pivotally turns to its open position away from pump head assembly 64 downwards, the curved surfaces 80 of this part and pump head assembly are away from enough distance, so that make conveyer conveyor trunk 52 install or to be inserted between pump head assembly and the part 72.Afterwards, when part 72 oppositely upwards pivotally turns to its make position towards pump head assembly 64, pipe 52 is clamped between the surface 80 of pump head assembly and part 72 (Fig. 2 and Fig. 3).The locking piece 82 (Fig. 1) of a routine releasably remains on part 72 on its make position.
When part 72 be in the close position and by locking piece 82 locking, make the part of pipe 52 be clamped between the surface 80 of pump head assembly 64 and part 72 and pump head assembly during by the rotation of the direction of arrow A (press anticlockwise motion as depicted in figs. 1 and 2), the visco-elastic material that is contained in the pipe is extracted and pumps into the syringe 12 interior (direction of arrow B among Fig. 2) that is clamped on the syringe clamper by this pipe from be received in the supply container 14 in mouthfuls 18.
Owing to be contained in the viscosity (Fig. 2) of the visco-elastic material 22 in the supply container 14, the discrepancy in elevation H of liquid may be not enough to guarantee pump into above-mentioned that pipe 52 is poured into by visco-elastic material always in the operating process.This just may cause formation air filled cavity or bubble in pipe 52, and thus in the suction syringe 12, this is that people are undesirable.
In order to prevent this potential air admission problem, in device 10, preferably include and be used for enough pressure supply container 14 pressurizations so that guarantee in pipe 52, can not form the device 90 (Fig. 1) of air filled cavity or bubble in the perfusion operation of syringe.As shown in the figure, pressure device 90 comprises an air pump 92, and its mouth is connected on the adaptive device 96 that is in supply container 14 tops by air duct 94.Therefore, preferably visco-elastic material 22 is contained in one sterile, in crushable plastic bag or the soft shell 98, pollute visco-elastic material with the foreign body in the pressurized air that prevents to form by air pump 92.Also have a reducing valve 100 on supply container 14 tops, be used to prevent supply container overvoltage (Fig. 1 and Fig. 2).
The above-mentioned air pressurized to the visco-elastic material supply container is feasible for the appearance that prevents bubble when syringe is poured into, some the time or even essential.Yet, do not think at present, only by not using ram type pump 60 just can finish satisfactorily memory fluid from supply container 14 this task in transfer tube 52 is sent to syringe 12 to the supply container pressurization.This is necessary because the micro-manipulation of the flow of visco-elastic material is that visco-elastic material with predetermined close pours into little volume syringe.
Device 10 also comprises electricity operation and control setup 110 (Fig. 5), and this device is used for the power operation of starter gear and is used to control this operation.Graphic what constitute electricity operation and control setup 110 is an AC/DC changeover switch (A/D) 112, and it accepts the AC line voltage of standard by the cable 114 with general ground terminal, at a free end of cable one three leg connection plug 116 is arranged.Plug 116 is used to insert in the battery socket 118 that is contained in advance on the building.General-duty ON/OFF source switch 120 (as depicted in figs. 1 and 2) is connected electrically on the power lead 114, and said source switch is connected on the front panel 122 of device case 16.
Typically, battery socket 118 provides 110 volts of alternating current, and A/D converter 112 provides 12 volts of direct current (DC) through out-put supply line 124.The material transfer pump timer switch 128 of perfusion switch of often opening 126 and Chang Kai is parallel on the power lead 124 by electric wire 130 and 132 respectively, and two switches all are connected on the housing front panel 122.
Perfusion switch 126 constitutes by this way: when with its closure, it remains closed preset time length t 1, unlatching automatically then.This preset time t 1Depend on liquid transfer pump 60 visco-elastic material in the visco-elastic material supply container 14 is filled into the required time in the empty fluid pipeline 52.
Transfer pump timer switch 128 is variable time switch, and it is manually operable or put fixed (Fig. 1,2 and 5) by a rotating control piece 134 that is exposed to front panel outside.Timer switch 128 has and is attached thereto, preferably with the scale 136 of milliliter (ml) delineation.Scale 136 can be used as an expose portion of switch 28, (as shown in the figure), perhaps, is engraved on the housing front panel around switch control piece 124.The scale of scale 136 is corresponding to the visco-elastic material in the supply container 14 is filled into the needed pump work time in the syringe 12 that is clamped on the syringe clamper 30 with selected dosage.
When perfusion one of switch 126 or pump time switch 128 are closed, be transferred on the normal opened contact 140 of control relay 142 through parallel power lead 130 and 132a and public power lead 144 from the vdc of AC/DC changeover switch 112.When relay tip 140 closures (below will illustrate), and one of switch 126 and 128 closure and source switch 120 are when closed, direct-current control voltage is transferred on the electrical motor 62 of visco-elastic material transfer pump 60 through electronic circuit 146 from AC/DC changeover switch 112, and is sent on the air pump 92 through electronic circuit 148.
The contact 140 of control relay 142 is by 150 controls of normally closed sensor, this sensor is installed on the syringe clamper 30 or on the position in its vicinity, be used for being filled into predetermined perfusion level by transfer pump 60 when the syringe that is clamped on the syringe clamper, during preferably maximum groundwater increment (Fig. 2), this state-detection is come out, sensor 150 can be a kind of common position transduser, for example, light-emitting diode and corresponding photoemissive element or hall effect device, this sensor energize (being in the state of " ON ") reaches predetermined syringe groundwater increment up to.
Vdc is supplied with the side (when source switch 120 and one of perfusion switch 126 and pump time switch 128 are closed) of sensors 150 through power lead 152, and power lead 152 is connected to the upstream side (A side) of relay tip 140, sees Fig. 5.Therefore, as long as sensor 150 keeps normally closed, vdc is transferred to through lead 154 on the control coil 156 of relay 142 by sensor, thus, makes the relay tip closure and remains closed startup drive pump 60 and air pump 92 work.Operation
The operation of device 10 is fully aware of from top detailed description, yet, in order to make it clearer and, will to be briefly described method of operation below for on-the-spot method with visco-elastic material perfusion syringe is described.
Attaching plug 116 is inserted in the socket 118.Visco-elastic material supply container 14 and the pipe 52 that is connected to its bottom inserted admit mouthfuls 20, that unclamps supporting member 72 and pivot turns to its open position (Fig. 1 and 2) by being directed downwards of arrow B, partly being inserted in the middle of the pipe 52 between supporting member surface 80 and the pump head assembly 64, supporting member is rotated back into its make position and in place with locking piece 82 lockings in the opposite direction then.To manage afterwards 52 free end from the top of housing 16 screw out and screw in syringe clamper 30 below part and cut the sealed end (not shown).
Then source switch 120 is connected.Do not have all then to pour into switch 126 and to connect if manage 52, make the transfer pump 60 can be thus according to the required schedule time length work of this pipe of perfusion with the perfusion of the visco-elastic material in the supply container 14.For this pumping operation, pump head assembly 64 rotates by the direction of arrow A with pump motor 62, and thus, pump head roller 70 sequentially flattens pipe 52 parts that enter between pump head assembly and the supporting member 72, in such a way, forces visco-elastic material to pass through this pipe.By kind of a reperfusion mode, the extended period that pumps into operation by pump 60 is by the decision of opening circuit of the time delay of perfusion switch 126.
Should be noted that electric control structure according to Fig. 5, air pump 92 and transfer pump 60 synchronous operations, so that to the supply container pressurization and force visco-elastic material to flow out into pipe 52 from soft shell 98, thus, it can pump into by transfer pump 60.Be also to be noted that sensing switch 150 keeps " closure ", so that the contact 140 of relay 142 is also remained closed and primer pump 60 and 92 work.
When pipe 52 has poured into visco-elastic material by aforesaid mode, make source switch 120 get back to " OFF " position.Syringe 12 is inserted in the syringe clamper 30, the free end of managing 52 is contained on the syringe end 56, afterwards, syringe 12 is locked on the syringe clamper 30 by locking piece 40.Regulate pump time switch 128 up on disk 136, indicating desired syringe groundwater increment (Fig. 1 and Fig. 2) by part 134.Then source switch 120 is got back on the position of " ON ", and to transfer pump 60 power supplies, till timer switch 128 cuts off automatically.Under aforementioned tube perfusion operational circumstances, air pump 90 and 60 synchronous operations of liquid transfer pump are so that the perfusion of assist injection device operation.
When carrying out the syringe perfusion, sensing switch 150 will remain closed, and thus, start syringe perfusion operation.Yet, under improper situation.When the syringe groundwater increment that is preset by time switch 128 reached, transfer pump 60 can not be realized cutting off, and visco-elastic material will continue to pump into syringe 12.In this case, when reaching the predetermined maximum groundwater increment of syringe 12, switch 150 will disconnect, relay coil 156 then loses excitation, and relay 140 will disconnect, thus, cut off the power supply of liquid transfer pump 60 and air pump 90, syringe perfusion operation stops.
After syringe perfusion operation is finished, source switch is got back to " OFF " position, the syringe 12 that has poured into is unclamped and take off from syringe clamper 30.Suppose that supply container 14 and pipe 52 do not use up by the perfusion syringe, necessary maintenance system, particularly visco-elastic material is aseptic, and this germ-free condition can keep by being locked on the syringe clamper 30 on the free end that the empty syringe 12 of a sterilization is connected to pipe 52 and syringe.Another kind method is with a suitable disinfectant cup or stopper (not shown) the open end of pipe 52 to be sealed, so that make visco-elastic material keep germ-free condition.
By installing 10, syringe 12 can be easy to and pour on the spot soon visco-elastic material as stated above.
Although the apparatus and method of on-the-spot syringe perfusion have been described, especially for the apparatus and method of automatically pouring into common syringe with the visco-elastic material scene in the visoelasticity container, according to embodiments of the invention use advantage of the present invention has been described, but should be understood that and the invention is not restricted to this.Therefore, the those of ordinary skill of medical professionalism can be made any improvement or the conversion that is equal to, but everything all is considered to drop within the protection domain of appended claims.

Claims (32)

1. syringe device for casting that is used for visco-elastic material perfusion syringe, this device comprises:
A. container holding device is used for admitting in removable mode the mouth of the supply container of visco-elastic material;
B. syringe clamper is used to admit and with common injector for medical purpose of removable mode clamping, will be poured in this syringe from by the visco-elastic material in the visco-elastic material supply container of admitting;
C. viscoelastic material conveyer, be used for visco-elastic material is sent to the discharge end that is received in the syringe in the said syringe clamper from the mouth of the visco-elastic material supply container that is received in said container holding device, and from sending into syringe here.
2. according to the described syringe device for casting of claim 1, wherein said visco-elastic material conveyer comprises a fluid pipeline, is used for mouth that is installed in the visco-elastic material supply container in the said container holding device and the discharge end that is installed in the syringe in the said syringe clamper are connected with each other.
3. according to the described injection device for casting of claim 2, wherein said fluid pipeline is made of the plastic pipe of a softness, and wherein said visco-elastic material conveyer comprises a plunger pump, this pump has a rotating pump head, a plurality of pump rollers that separate are housed on the pump head, are used for getting visco-elastic material by said plastic pipe pump.
4. according to the described syringe device for casting of claim 3, comprise and be installed near the supporting member of said pump head, be used for opening between position and the make position and pivotally rotate at one, on the open position, the part of said plastic pipe can be between supporting member and pump head, in make position, pump head rotates by the operation of said pump, make the pump roller sequentially compress the pipe of the softness between pump head and supporting member, by this mode, make visco-elastic material by pumping in the syringe that is received in the said syringe clamper the visco-elastic material supply container of this pipe in being received in holding device.
5. according to the described syringe device for casting of claim 4, wherein said notes plug pump is configured by the automatically controlled form of external power supply, and comprises the controller for electric consumption of the operation that is used to control said pump.
6. according to the described syringe device for casting of claim 5, electrical controller wherein is used to start the perfusion operation of said pump, so that the pipe between pump head and supporting member can be poured into by the visco-elastic material in the supply container that is received in the visco-elastic material in the said container holding device in advance.
7. according to the described automatic syringe device for casting of claim 5, wherein said electrical controller comprises a graduated pump timer, and being used to change will be by said pump from being in the dosage that visco-elastic material supply container in the said container holding device is sent to the visco-elastic material in the syringe that is contained in the said syringe clamper.
8. according to the described automatic syringe device for casting of claim 5, a sensor has been installed in the wherein said electrical controller, and its effect is that the syringe on being installed in the syringe clamper has been used by the operation of said pump and detected this state and the said pump of cut-out on said predetermined groundwater increment when being filled into predetermined groundwater increment from the visco-elastic material in the visco-elastic material supply container that is received in said admit mouthful.
9. according to the described syringe device for casting of claim 3, be integrally formed on the output end region of the visco-elastic material supply container of the pipe of said softness in being received in the container holding device wherein.
10. according to the described syringe device for casting of claim 1, comprise a pressure device that is used to compress the visco-elastic material supply container that is received in said admittance mouth.
11. according to the syringe device for casting that claim 10 is stated, wherein said pressure device comprises an air pump and is used for the device of control air pump.
12. an automatic syringe device for casting that is used for visco-elastic material perfusion syringe, said device comprises:
A. one has the housing of admitting mouthful, admits mouth to be used for admitting removably the mouth of the supply container of visco-elastic material; With one be used to admit and with the syringe clamper of removable mode clamping by the injector for medical purpose of the routine of said visco-elastic material supply container perfusion.
B. be used to admit the device of a flexible hose in said housing, described flexible hose is used for being connected with each other being installed in said mouthful mouth of interior visco-elastic material supply container and the discharge end that is installed in the syringe in the said syringe clamper of admitting.
C. one is installed in the interior ram type pump of said housing, and said pump has a rotating pump head, and said pump head has a plurality of pump rollers that separate mounted thereto on circumference, be used for contacting with the some parts that is received in the pipe in the housing;
D. supporting member of pivotally moving in open position and make position of being used for that is contained in the housing near the roller place of said pump, in the open position, when pump head rotates, pipe between pump head and supporting member is not subjected to the compression of pump roller significantly, in make position, when pump head rotates, pipe between pump head and supporting member will be subjected to the compression of pump roller, thus, when pump head rotates by suitable direction, cause being contained in the visco-elastic material supply container of visco-elastic material in being received in an opening in the pipe being pumped into forward in the syringe that is received in said second opening;
E. be used to compress a device that is contained in said admittance mouthful interior visco-elastic material supply container.
13. according to the described automatic syringe device for casting of claim 12, wherein said plunger pump is by the external power supply electric control, and comprise be attached thereto be used to control said pump operated electrical controller, said electrical controller is used to start the first perfusion operation of said pump, be contained between pump head and the supporting member and supporting member when being in the close position with the soft pipe of box lunch, make the said pipe can be by the visco-elastic material perfusion in advance in the visco-elastic material supply container that is received in said admit mouthful.
14. according to the described automatic syringe device for casting of claim 13, wherein said pressure device comprises the air pump of an electricity operation, and wherein said connected electrical controller is used to operate the said air pump that is associated with the operation of said plunger pump.
15. according to the described automatic syringe device for casting of claim 13, wherein said electrical controller comprises the former time meter of a band scale, is used for extracting the visco-elastic material of different amounts by plunger pump in the syringe that is contained in the said syringe clamper from being received in the said mouthful interior visoelasticity material supply container of admitting.
16. according to the described automatic syringe device for casting of claim 13, a sensor is housed in the wherein said electrical controller, its effect is that the syringe on being installed in the syringe clamper is used by the visco-elastic material in the visco-elastic material supply container that is received in said admit mouthful by the operation of said pump and has been filled into when being scheduled to groundwater increment once more, detect this information, and then stop the operation of said pump when said predetermined once more syringe groundwater increment by sensor automatically.
17. according to the described syringe device for casting of claim 12, wherein the pipe of said softness forms at the output end region and the visco-elastic material supply container of said container.
18. the automatic syringe device for casting of the visco-elastic material in-site pouring syringe of a supply container that is used for visco-elastic material, said supply container has an elongated flexible hose that is connected on its mouth, and said device comprises:
A. one has the casing device of admitting mouthful, said admittance mouth be used to admit the supply container that is contained in the visco-elastic material in the housing output end region and on elongated pipe;
B. syringe clamper, being used to admit will be by the common syringe of said visco-elastic material supply container perfusion with clamping, and said syringe clamper makes dress syringe thereon and is received in the said mouthful relation that the output end region of interior visco-elastic material supply container is maintained fixed of admitting;
C. one is contained in the memory fluid pump that the interior electricity of said housing is operated, and said liquid pump has a rotating pump head, and a plurality of pump rollers that separate are housed on the said pump head, and some zones that these pump rollers are used for the elongated tubular interior with being received in housing contact;
D. one is contained near the interior supporting member said liquid pump of said housing, this part is used for pivotally motion between the make position of open position, in the open position, when said elongated tubular between liquid pump pump head and supporting member, and when pump head rotates, said pipe is not subjected to the compression of pump roller significantly, in make position, when rotating, liquid pump pump head is subjected to the compression of pump roller at the pipe between liquid pump pump head and the supporting member, therefore, visco-elastic material admits mouthful supply container of interior visco-elastic material in described pipe pumps into the syringe that is contained on the syringe clamper by being received in;
E. an automatically controlled air pump is used for being received in said supply container pressurization of admitting mouthful interior visco-elastic material;
F. electrical controller is used to make said visco-elastic material liquid pump optionally to operate and said liquid pump pump head is rotated, and also is used to make said air pump work.
19. according to the described automatic syringe device for casting of claim 18, wherein said electrical controller is used to start the first perfusion operation of said memory fluid pump, between liquid pump pump head and supporting member and supporting member when being in the close position, make said Guan Nengyong with the pipe of convenient visco-elastic material supply container from the perfusion in advance of the visco-elastic material in the said supply container.
20. according to the described automatic syringe device for casting of claim 19, wherein said electrical controller comprises the liquid pump timer of the band scale of an artificial selection, is used for extracting the visco-elastic material of various dose by said liquid pump in the syringe that is contained on the said syringe clamper from being received in the said mouthful supply container of interior visco-elastic material of admitting.
21. according to the described automatic syringe device for casting of claim 20, wherein said electrical controller is used for controlling said air pump work when said liquid pump work.
22. according to the described automatic syringe device for casting of claim 19, a sensor has been installed in the wherein said electrical controller, when being used for the operation of syringe by said liquid pump on being installed in the syringe clamper and being filled into predetermined groundwater increment by visco-elastic material from the supply container that is received in the visco-elastic material in admitting mouthful, detect this information, and the syringe on being clamped in the syringe clamper automatically cuts off the operation of said liquid pump when being filled into predetermined groundwater increment by visco-elastic material.
23. a method that is used for pouring into visco-elastic material on the spot syringe, said method comprises the steps:
A., a supply container that will be used to pour into the visco-elastic material of syringe is provided;
B. by fluid pipeline the syringe needle fixed end of syringe is connected to the mouth of said container;
C. make visco-elastic material flow into said syringe through said pipeline from the supply container of visco-elastic material.
24. according to the described method that is used for pouring on the spot syringe of claim 23, comprise step, so that help visco-elastic material to flow into syringe from supply container to the supply container pressurization of said visco-elastic material.
25., be included in and syringe be connected to before the said pipe step of pouring into said fluid pipeline with the visco-elastic material in the supply container in advance according to the described method that is used for pouring on the spot syringe of claim 23.
26., comprise the step that the mouth of the supply container of said fluid pipeline and said visco-elastic material is formed one according to the described method that is used for pouring on the spot syringe of claim 23.
27. according to the described method that is used for pouring on the spot syringe of claim 23, when being included in the perfusion of the visco-elastic material in said supply container syringe, with respect to the supply container of said visco-elastic material, said syringe is clamped in a step on the fixed position in removable mode.
28. according to the described method of pouring into syringe on the spot of claim 23, the step that comprises the pipeline that forms soft plastic pipe, and in the step that visco-elastic material flows by pipeline, comprise the plastic pipe that little by little flattens said softness, make supply container the step through this pipe inflow said syringe of visco-elastic material from visco-elastic material.
29. according to the described method of pouring into syringe on the spot of claim 28, the step of wherein flattening plastic pipe comprises with a plunger liquid pump with pump head roller passes through this pipe extraction visco-elastic material, makes this be in control the step of compression completely during with convenient pump work.
30. according to the described method of pouring into syringe on the spot of claim 29, comprise the step of controlling liquid pump, so that have only the visco-elastic material of predetermined close to be pumped in institute's bonded assembly syringe.
31. according to the described method of pouring into syringe on the spot of claim 30, comprise when the amount that pumps into the visco-elastic material in the syringe by the liquid pump reaches predetermined perfusion, the step that this state-detection is come out and when reaching predetermined groundwater increment, automatically cut off the step of liquid pump.
32. according to the described method that is used for pouring on the spot syringe of claim 32, comprise when pouring into said syringe, press the step of fixed relationship with removable this syringe of mode clamping with respect to said supply container with the liquid pump.
CN 96122434 1996-09-12 1996-09-12 On-site syringe filling apparatus for viscoelastic materials, and corresponding method for on-site syringe filling Pending CN1176222A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 96122434 CN1176222A (en) 1996-09-12 1996-09-12 On-site syringe filling apparatus for viscoelastic materials, and corresponding method for on-site syringe filling

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 96122434 CN1176222A (en) 1996-09-12 1996-09-12 On-site syringe filling apparatus for viscoelastic materials, and corresponding method for on-site syringe filling

Publications (1)

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CN1176222A true CN1176222A (en) 1998-03-18

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108472442A (en) * 2016-01-14 2018-08-31 艾浓·威驰赛尔巴母 Viscoplasticity spring injector

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108472442A (en) * 2016-01-14 2018-08-31 艾浓·威驰赛尔巴母 Viscoplasticity spring injector

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