CN117582232A - Portable electrophysiological signal acquisition circuit for brain-computer interface - Google Patents

Portable electrophysiological signal acquisition circuit for brain-computer interface Download PDF

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Publication number
CN117582232A
CN117582232A CN202311632648.6A CN202311632648A CN117582232A CN 117582232 A CN117582232 A CN 117582232A CN 202311632648 A CN202311632648 A CN 202311632648A CN 117582232 A CN117582232 A CN 117582232A
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module
portable
acquisition circuit
signal acquisition
analog
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徐光远
肖博阳
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Beijing University of Posts and Telecommunications
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Beijing University of Posts and Telecommunications
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/30—Input circuits therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0006—ECG or EEG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/002—Monitoring the patient using a local or closed circuit, e.g. in a room or building
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/30—Input circuits therefor
    • A61B5/305—Common mode rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/30—Input circuits therefor
    • A61B5/307—Input circuits therefor specially adapted for particular uses
    • A61B5/31—Input circuits therefor specially adapted for particular uses for electroencephalography [EEG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/30—Input circuits therefor
    • A61B5/307—Input circuits therefor specially adapted for particular uses
    • A61B5/313—Input circuits therefor specially adapted for particular uses for electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/725—Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0204—Operational features of power management
    • A61B2560/0214—Operational features of power management of power generation or supply
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0431—Portable apparatus, e.g. comprising a handle or case

Abstract

The invention provides a portable electrophysiological signal acquisition circuit for a brain-computer interface. The acquisition circuit comprises a control module, a power supply driving module, an analog-to-digital conversion module, a clock module, an external operational amplifier module, a Bluetooth transmission module, an electrode and a lead module. The Bluetooth transmission module and other modules are integrated on the same PCB, so that the volume and weight of hardware are reduced, and the cost is reduced; noise interference sources such as a Bluetooth transmission module, a control module, a power module and the like are arranged at the edge of the PCB, so that low noise of signal transmission is ensured. The circuit covers the main frequency range of the electromyographic signals and the electroencephalogram signals, and accords with the application of the general electrophysiological signals. The invention optimizes the layout of the PCB, the wiring and the circuit components, reduces the line impedance and the interference, improves the common mode rejection ratio to 109dB, combines the filter algorithm and the console software development, can realize the acquisition, the identification and the analysis of the multichannel electrophysiological signals, and improves the application range of the electrophysiological signals.

Description

Portable electrophysiological signal acquisition circuit for brain-computer interface
Technical Field
The invention relates to the technical field of medical instrument data acquisition devices, in particular to a portable electrophysiological signal acquisition circuit for a brain-computer interface.
Background
Owing to the development of information technology, health analysis and Internet medicine, the electrophysiological signal acquisition hardware has been greatly developed in recent years, and the electrophysiological signal acquisition equipment has a large demand and has great application in various civil fields such as medical treatment. In addition, due to the rapid development of brain-computer interface technology applications, a specially designed hardware circuit of the portable electrophysiological device is required, and this type of hardware circuit is required to have high sensitivity, low noise, and high signal-to-noise ratio. On the premise of ensuring the accuracy of the brain-computer signal, the high-sensitivity electrophysiological signal acquisition circuit has better prospect and research necessity in the aspects of miniaturization, portability, low cost and the like according to the application scene of the brain-computer interface.
In the medical field, the brain-computer interface system is widely applied to different rehabilitation and treatment scenes, and the requirements of hardware equipment are enhanced. The fields of sports rehabilitation, intelligence rehabilitation and the like provide requirements for the stability and mobility of equipment, and a wireless mobile electroencephalogram acquisition hardware device is needed. In summary, the electrophysiological signals need to be miniaturized and moved, and the circuit meeting the conditions has wider application prospect than the traditional equipment.
The current portable electrophysiological signal acquisition hardware commonly used data transmission technical schemes include the following: wireless network transmission, bluetooth transmission, serial port transmission. The invention patent with application number 201110408031.7 discloses a portable wireless brain electricity acquisition device, wherein a wireless transceiver is adopted to work in a global open 2.400-2.4835GHz frequency band, the communication baud rate of the transceiver is set to work at 250kbps, 1IMbps and 2Mbps through software, and the device is transmitted through zigbee protocol, so that compared with Bluetooth, the device has lower transmission rate and weaker universality for an upper computer.
The existing portable electrophysiological signals have the following disadvantages to be improved: the relatively heavy electrophysiological circuit for transmitting data, especially the wireless network, comprising a power supply and a control system, can weigh up to 250g, and cause extra pressure on the head and neck of a subject; the cost is high, and a built-in microprocessor development board is required to be additionally purchased to process transmission data; the installation is troublesome and the connection is tedious, and the interface can cause extra noise to reduce circuit noise performance.
Disclosure of Invention
Aiming at the defects existing in the prior art, the invention aims to provide a portable electrophysiological signal acquisition circuit for a brain-computer interface, and Bluetooth transmission has obvious advantages in the aspects of short distance, low power consumption, real-time transmission and the like, and is suitable for equipment which needs simple and quick connection such as portable electroencephalogram acquisition hardware, so that a Bluetooth protocol is used as a final transmission technical scheme. Bluetooth transmissions are transmitted via device discovery and pairing, establishing a connection, and following a communication protocol.
In order to solve the technical problems, the technical scheme provided by the invention is as follows:
a portable electrophysiological signal acquisition circuit for brain-computer interface,
the electrophysiological signal acquisition circuit comprises an electrode module, a lead module, a power module, a control module, an analog-to-digital conversion module, a clock module, an external operational amplifier module and a Bluetooth transmission module;
one end of the electrode is connected with the lead module, and the other end of the electrode is connected with the analog-digital conversion module;
one end of the control module is connected with the analog-to-digital conversion module, and the other end of the control module is connected with the Bluetooth transmission module;
the analog-to-digital conversion module is used for converting the analog electrophysiological signals into high-precision digital signals, and the high-precision digital signals are transmitted to the upper computer through the Bluetooth transmission module after being read by a control program of the control module;
the power supply module is connected with the analog-to-digital conversion module; the power supply module is also connected with the analog-to-digital conversion module through the clock module and the external operational amplifier module;
the Bluetooth transmission module and the power supply module are arranged at the edge of the acquisition circuit as potential noise signal interference sources; the Bluetooth transmission module is arranged at a position far away from the analog-to-digital conversion module;
the working frequency range of the acquisition circuit is 0.5-1000Hz, and the signal amplitude is 0.5 mu V-1000 mu V.
Preferably, the analog-to-digital conversion module comprises an analog-to-digital conversion Chip ADS1299 and a peripheral circuit, wherein the analog-to-digital conversion Chip ADS1299 is provided with the following pins for SPI communication, including Chip Select, SPI Clock, master In Slave Out and Master Out Slave In, and the pins are used for receiving instructions and reading and writing registers.
Preferably, the control module includes a microprocessor that selects STM32F407.
Preferably, the bluetooth transmission module selects RN42 or HC05.
Preferably, the external operational amplifier module is OPA376.
Preferably, the power module includes a voltage inverter, and a 1 μf capacitor is used for converting +5v voltage into-5V, and providing high precision voltage regulators of-2.5V and +2.5v voltages, respectively, for the analog-to-digital conversion chip and the external operational amplifier module.
Preferably, the voltage reverser is TPS60403, and the high-precision voltage stabilizer for providing-2.5V and +2.5V voltages is TPS72325 and TPS73225 respectively.
Preferably, the electrode and the lead module are used for connecting the analog-digital conversion chip with a human body, and the impedance of the electrode is lower than 5k omega.
Preferably, the external clock module adopts a clock chip FXO-HC73 to provide an external clock for the analog-digital conversion module, and the frequency of the external clock is 2.048MHz.
The beneficial effects of the invention are as follows:
1. the working frequency range of the multichannel portable electrophysiological signal acquisition equipment is 0.5-1000Hz, the signal amplitude is 0.5 mu V-1000 mu V, the main frequency range of the electromyographic signals and the electroencephalogram signals is covered, the multichannel portable electrophysiological signal acquisition equipment meets the purposes of common electrophysiological signals, and the common mode rejection ratio can reach 109dB by testing, which is far more than 80dB of medical instrument requirements;
2. the wireless transmission module consisting of the microprocessor and the Bluetooth module can realize the wireless transmission function, is connected with a Bluetooth serial port of a computer, combines a filtering algorithm and control desk software development, can realize multichannel electrophysiological signal acquisition, identification and analysis, and improves the application range of electrophysiological signals to the greatest extent;
3. by arranging the wireless transmission module at a position far away from the analog-to-digital conversion module, the wiring length from the electrode to the analog-to-digital conversion chip is shortened, the interference source and the wiring impedance are reduced, and the short-circuit noise amplitude is reduced. In addition, the integrated microprocessor chip and the wireless transmission module reduce the number of interfaces on the electrophysiological signal acquisition circuit, thereby reducing the impedance of the contact surface and the amplitude of noise.
4. The external control system is canceled, the original external controller raspberry group 4B is canceled, the modules are simplified under the function of realizing wireless transmission, and the weight of equipment and the specification of an external power supply are reduced. In addition, the external control system of the raspberry group 4B and the wireless transmission module are omitted, the module is replaced by the STM32F407 with low power consumption, the maximum power consumption is lower than 3W, and the raspberry group with standby power consumption is obviously better than 3W, so that the energy consumption is obviously reduced.
5. The performance is guaranteed, the cost is reduced, and the Bluetooth chip HC05 is adopted, so that the cost is reduced by 90%.
Drawings
The accompanying drawings are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate the invention and together with the embodiments of the invention, serve to explain the invention. In the drawings:
FIG. 1 is a schematic diagram of the circuit diagram of the present invention
FIG. 2 is a schematic diagram of the overall module principle of the system of the present invention
FIG. 3 is a schematic diagram of the ADC module according to the present invention
FIG. 4 is a schematic diagram of a microprocessor cache module according to the present invention
Detailed Description
The following description of preferred embodiments of the present invention is provided in connection with the accompanying drawings, and it is to be understood that the preferred embodiments described herein are for the purpose of illustration and explanation only and are not intended to limit the invention thereto.
The invention provides a portable electrophysiological signal acquisition circuit for a brain-computer interface, which mainly comprises a control module, a power driving module, an analog-to-digital conversion module, a clock module, an external operational amplifier module, an electrode and a lead module. One end of the electrode is connected with the lead module, and the other end of the electrode is connected with the analog-to-digital conversion module; one end of the control module is connected with the analog-to-digital conversion module, and the other end of the control module is connected with the Bluetooth transmission module; the analog-to-digital conversion module is used for converting the analog electrophysiological signals into high-precision digital signals, and the high-precision digital signals are transmitted to the upper computer through the Bluetooth transmission module after being read by a control program of the control module; the power supply module is connected with the analog-to-digital conversion module; the power module is also connected with the analog-to-digital conversion module through the clock module and the external operational amplifier module. The logical relationship between the modules is shown in fig. 1.
Fig. 2 is a schematic diagram of the overall module principle of the system of the present invention.
The design of the hardware system of the invention takes an analog-to-digital conversion module (ADC) as a core, and peripheral modules are added according to functions. The analog-to-digital conversion is composed of an analog-to-digital conversion chip ADS1299 and a peripheral circuit thereof, and is used for converting an analog electrophysiological signal into a high-precision digital signal for reading by a control program of an STM32F407 singlechip control module, and then transmitting the digital signal to an upper computer through a Bluetooth module. The ADS1299 Chip has the following pins for SPI communication, including Chip Select (CS), SPI Clock (SCLK), master In Slave Out (MISO) and Master Out Slave In (MOSI), for receiving instructions and reading and writing registers. The wiring of 64 pins of the ADS1299 chip is shown in fig. 2.
The Power Supply module (Power Supply) includes a voltage inverter TPS60403, three small 1 μf capacitors for converting +5v voltage to-5V, high precision voltage regulators TPS72325 and TPS73225 with reverse current protection, respectively providing-2.5V and +2.5v voltages for use by the analog-to-digital conversion chip and the operational amplifier.
Electrodes and lead modules (Electrodes & Leads) are used for connection of the analog-to-digital conversion chip to the human body, wherein the Electrodes require an impedance lower than 5kΩ to enable transmission of μv level signals.
The external Clock module (Clock) uses a high-precision Clock chip FXO-HC73 to provide an external Clock with the frequency of 2.048MHz for the analog-digital conversion module and meets the Clock precision requirement of the chip.
The external operational amplifier module OPA376 is used for buffering the reference electrode and Bias driving electrode, so that the signal baseline is positioned in the center of the working range of the analog-digital conversion chip.
The Bluetooth module RN42 and the microprocessor module respectively preprocess, cache and package the data and send the data to the upper computer. The microprocessor selects STM32F407 as the microprocessor, so that the stability is better. The Bluetooth selects two widely applied Bluetooth transmission modules of RN42 or HC05 as transmission modules, thereby realizing the guarantee of the requirement of stability and the requirement of high-speed high-quality data transmission.
Fig. 3 is a schematic diagram of an ADC module according to the invention.
FIG. 4 is a schematic diagram of a microprocessor cache module according to the present invention.
The technical indexes met by the invention are as follows: the working frequency ranges from 0.5Hz to 1kHz (mainly distributed at 1-60 Hz), the average value of short-circuit noise is 7.5 mu V, and the common mode rejection ratio is more than 80dB (10-60 Hz). The circuit is capable of implementing predetermined technical standards.
Compared with the existing multichannel portable electrophysiological signal acquisition system, the system combines the Bluetooth connection technology and the STM32F407 chip, integrates the Bluetooth transmission module and other modules on the same PCB, reduces the volume and weight of hardware, can realize the portability requirement, can meet the actual application under the scene of needing the mobile performance (such as the sports electroencephalogram analysis and the sports electrocardiogram acquisition), and improves the application scene and the practicability; and, the chip gives consideration to both performance and cost.
The invention combines with the Bluetooth transmission technology, and can transmit eight channels of electrophysiological signals at most in real time; and a proper chip is selected according to technical indexes, so that the standard of the medical electrophysiological acquisition instrument is reached, and the technical requirements of high common mode rejection ratio and low noise are met.
According to the invention, a Bluetooth HC05 or RN42 chip is selected, the cost is reduced, meanwhile, the two chips are creatively used as a PCB design, interference sources of potential noise signals such as a Bluetooth transmission module, a control module, a power module, an external operational amplifier and a clock module are arranged at the edge of the PCB, the interference sources are arranged at the position where the distance between the analog-digital conversion module and the PCB is more than 10mm, the PCB layout is optimized, the low noise of signal transmission is ensured, the line impedance and interference are reduced, the common mode rejection ratio is improved to 109dB, the medical instrument requirement of far exceeding 80dB is met, the short circuit noise average value is as low as 0.11 mu V under the main working sampling rate (250 SPS-1000 SPS), and the minimum level in the same type of circuit is achieved.
The electrophysiological signal acquisition device in the prior art adopts wireless network to transmit through zigbee protocol, and also needs an external control system, so that the transmission rate is low, the power consumption is high, the universality of an upper computer is weak, the weight is heavy, the installation is troublesome, the connection is cumbersome, and the interface can also cause extra noise to reduce the noise performance of a circuit.
The portable electrophysiological signal is used for the brain-computer interface system, has harsh use environment, needs to fully consider biocompatibility and biomechanical characteristics, and has high requirements on stability and portability of a circuit.
Compared with the conventional prior art scheme adopting Wi-Fi, the technical scheme adopts the transmission technical scheme combining a Bluetooth module, a microprocessor module STM32F407 and a combination, and introduces an SD card module for data caching (the special combination mode of the three modules is shown in figure 1 of the specification). The scheme does not need to install an additional transceiver module and software drive, an external control system is also canceled, the extra weight of an external battery is reduced, the signal bandwidth can meet the requirements and the transmission is stable, the number of interfaces and the impedance and the noise of a contact surface are reduced by adopting an integrated microprocessor chip and a wireless transmission module on an electrophysiological signal acquisition circuit board, the cost can be reduced by selecting special electronic components, the method has obvious advantages in the aspects of short distance, low power consumption, real-time transmission and the like, the development threshold and the iteration time are reduced, and the method is suitable for equipment which needs simple and quick connection such as portable electroencephalogram acquisition hardware.
The invention uses Bluetooth transmission to find and pair with equipment, establishes connection, transmits according to a communication protocol, and realizes the following functions through the Bluetooth protocol:
(1) Real-time monitoring and remote transmission: the Bluetooth protocol allows the brain electrical signals to be transmitted to the remote equipment in real time, so that medical staff can monitor the brain electrical activity of a patient in real time and take necessary measures in time.
(2) Wireless connectivity and portability: compared with the traditional wired connection, the Bluetooth technology eliminates the complicated cable, improves the portability and comfort of the equipment, and enables patients to move freely in the use process.
(3) Multi-device connection: bluetooth technology supports simultaneous connection of multiple devices, which means that brain electrical signals can be transmitted to multiple receiving devices, such as medical monitoring devices and personal smartphones, enhancing the utilization and dissemination of data.
(4) And (3) reducing power consumption: the bluetooth protocol provides a Bluetooth Low Energy (BLE) mode, greatly extending the battery life of the device, and is suitable for long-time electroencephalogram monitoring and recording.
(5) And (3) safe transmission: the Bluetooth protocol supports encrypted transmission of data, so that privacy and safety of electroencephalogram data are protected, and information cannot be acquired by unauthorized persons.
(6) Flexibility and scalability: the bluetooth protocol provides a plurality of configuration options and service characteristics, can be customized according to specific requirements, and simultaneously provides convenience for the expansion of subsequent functions.
(7) Scalability: the Bluetooth technology supports the development of various application programs, and can realize functions of real-time analysis, data storage, report generation and the like on an upper computer.
The invention has the unique advantages that the invention can be compatible with various portable mobile power supplies for power supply, has enough sampling precision compared with the prior commercial large-scale electrophysiological signal acquisition equipment, is suitable for the development direction of the electrophysiological signal acquisition equipment in brain-computer interfaces, rapid medical diagnosis and health monitoring, has extremely wide application range and saves a lot of cost.
What is not described in detail in this specification is prior art known to those skilled in the art.
Finally, it should be noted that: the foregoing is merely a preferred example of the present invention, and the present invention is not limited thereto, but it is to be understood that modifications and equivalents of some of the technical features described in the foregoing embodiments may be made by those skilled in the art, although the present invention has been described in detail with reference to the foregoing embodiments. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (9)

1. A portable electrophysiological signal acquisition circuit for a brain-computer interface is characterized in that,
the electrophysiological signal acquisition circuit comprises an electrode module, a lead module, a power module, a control module, an analog-to-digital conversion module, a clock module, an external operational amplifier module and a Bluetooth transmission module;
one end of the electrode is connected with the lead module, and the other end of the electrode is connected with the analog-digital conversion module;
one end of the control module is connected with the analog-to-digital conversion module, and the other end of the control module is connected with the Bluetooth transmission module;
the analog-to-digital conversion module is used for converting the analog electrophysiological signals into high-precision digital signals, and the high-precision digital signals are transmitted to the upper computer through the Bluetooth transmission module after being read by a control program of the control module;
the power supply module is connected with the analog-to-digital conversion module; the power supply module is also connected with the analog-to-digital conversion module through the clock module and the external operational amplifier module;
the Bluetooth transmission module, the control module, the power module, the external operational amplifier and the clock module are all arranged at the position, with the distance between the analog-digital conversion module and the power module being more than 10 mm;
the working frequency range of the acquisition circuit is 0.5-1000Hz, and the signal amplitude is 0.5 mu V-1000 mu V.
2. The portable electrophysiological signal acquisition circuit of claim 1, wherein the portable electrophysiological signal acquisition circuit is configured to receive the signal from the brain-computer interface,
the analog-to-digital conversion module comprises an analog-to-digital conversion Chip ADS1299 and a peripheral circuit, wherein the analog-to-digital conversion Chip ADS1299 is provided with the following pins for SPI communication, including a Chip Select, SPI Clock, master In Slave Out and Master Out Slave In, and the pins are used for receiving instructions and reading and writing registers.
3. The portable electrophysiological signal acquisition circuit of claim 1, wherein the portable electrophysiological signal acquisition circuit is configured to receive the signal from the brain-computer interface,
the control module includes a microprocessor that selects STM32F407.
4. The portable electrophysiological signal acquisition circuit of claim 1, wherein the portable electrophysiological signal acquisition circuit is configured to receive the signal from the brain-computer interface,
the Bluetooth transmission module selects RN42 or HC05.
5. The portable electrophysiological signal acquisition circuit of claim 1, wherein the portable electrophysiological signal acquisition circuit is configured to receive the signal from the brain-computer interface,
the external operational amplifier module is OPA376.
6. The portable electrophysiological signal acquisition circuit of claim 1, wherein the portable electrophysiological signal acquisition circuit is configured to receive the signal from the brain-computer interface,
the power supply module comprises a voltage inverter, a 1 mu F capacitor is used for converting +5V voltage into-5V, and a high-precision voltage stabilizer for respectively providing-2.5V and +2.5V voltages is used for the analog-digital conversion chip and the external operational amplifier module.
7. The portable electrophysiological signal acquisition circuit of claim 6, wherein the portable electrophysiological signal acquisition circuit is configured to receive the signal from the brain-computer interface,
the voltage reverser is TPS60403, and the high-precision voltage stabilizer for providing-2.5V and +2.5V voltages is TPS72325 and TPS73225 respectively.
8. The portable electrophysiological signal acquisition circuit of claim 1, wherein the portable electrophysiological signal acquisition circuit is configured to receive the signal from the brain-computer interface,
the electrode and the lead module are used for connecting the analog-digital conversion chip with a human body, and the impedance of the electrode is lower than 5k omega.
9. The portable electrophysiological signal acquisition circuit of claim 1, wherein the portable electrophysiological signal acquisition circuit is configured to receive the signal from the brain-computer interface,
the external clock module adopts a clock chip FXO-HC73 to provide an external clock for the analog-digital conversion module, and the frequency of the external clock is 2.048MHz.
CN202311632648.6A 2023-11-30 2023-11-30 Portable electrophysiological signal acquisition circuit for brain-computer interface Pending CN117582232A (en)

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