CN117582193A - blood pressure measuring catheter - Google Patents

blood pressure measuring catheter Download PDF

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Publication number
CN117582193A
CN117582193A CN202311375097.XA CN202311375097A CN117582193A CN 117582193 A CN117582193 A CN 117582193A CN 202311375097 A CN202311375097 A CN 202311375097A CN 117582193 A CN117582193 A CN 117582193A
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CN
China
Prior art keywords
blood pressure
proximal portion
pressure sensor
distal
pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202311375097.XA
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Chinese (zh)
Inventor
柯著漳
郑欲晓
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Insight Lifetech Co Ltd
Original Assignee
Insight Lifetech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insight Lifetech Co Ltd filed Critical Insight Lifetech Co Ltd
Priority to CN202311375097.XA priority Critical patent/CN117582193A/en
Publication of CN117582193A publication Critical patent/CN117582193A/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6876—Blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0172—Exchanging a guidewire while keeping the catheter in place

Abstract

The present disclosure provides a blood pressure measurement catheter comprising: a distal cannula, a proximal portion and a pressure sensor; the distal cannula has a guidewire lumen; the proximal portion is coupled to the distal cannula; the pressure sensor is disposed within the lumen of the proximal portion and separates the lumen of the proximal portion into a measurement cavity in communication with the guidewire lumen of the distal cannula, the pressure sensor being configured to measure blood pressure of blood flowing into the measurement cavity via the distal cannula and to generate a blood pressure signal. The blood pressure measuring catheter provided by the disclosure can reduce the thickness of the distal sleeve and avoid forming a bulge, so that the distal sleeve can pass through a narrower lesion, the application range is widened, and the pushability of the pressure catheter in a blood vessel is also increased.

Description

Blood pressure measuring catheter
The present application is a divisional application of patent application with application number 2019107101097 and name intravascular pressure measurement catheter, with application date 2019, 8 and 2.
Technical Field
The present invention relates to a blood pressure measuring catheter.
Background
The fractional flow reserve (FFR: fractional Flow Reserve) of coronary artery refers to the ratio of the maximum blood flow obtained in the myocardial area supplied by the blood vessel to the maximum blood flow obtained in the same area theoretically and normally under the condition that the coronary artery has stenosis, and is now an index for evaluating the invasive function, which has important guiding significance for the treatment strategy of coronary heart disease. In medicine, FFR is widely used, and functional myocardial ischemia of coronary heart disease is accurately diagnosed, so that doctors are helped to determine whether stenosis exists or not and whether a cardiac stent implantation technique (PCI: percutaneous Coronary Intervention) is needed. Meanwhile, the method can also be used for evaluating the curative effect after stent implantation, can accurately reflect the functional severity of pathological stenosis through FFR, help doctors to select the interventional therapy indication more objectively, guide the stent to be implanted optimally and judge the curative effect and the long-term curative effect. For example, when FFR is less than 0.7-0.8, coronary critical lesions should be considered for stenting or coronary bypass. Therefore, by judging the FFR, a doctor can be well helped to make accurate judgment, and excessive treatment caused by misjudgment of the doctor is avoided.
Currently, pressure sensing catheters with Rapid Exchange (RX) ports are mostly used, the distal part of which has a lumen through which a guide wire is threaded, and by fitting the distal part over the guide wire, the pressure sensing catheter can be moved to a predetermined position along the guide wire. Before coronary intervention, the pressure sensing catheter was passed through the distal and proximal (right) sides of the stenosis, and the distal and proximal blood pressures were recorded, respectively. Thus, the FFR value of the stenosis can be calculated.
However, the placement of the pressure sensor often results in a raised portion of the pressure sensing catheter (where the pressure sensor is located), which may be difficult to traverse through some of the more severe stenosed portions as the pressure sensing catheter is moved along the guidewire within the vessel, failing to detect the pressure at the stenosed site. In addition, in the process that the pressure sensing catheter passes through the stenosis, the pressure sensor is likely to be in contact with the stenosis, so that the measurement of the pressure sensor is affected, an accurate FFR value cannot be obtained, and an accurate judgment basis cannot be provided for doctors.
Disclosure of Invention
The present disclosure is directed to the above-mentioned problems occurring in the prior art, and provides an intravascular pressure measurement catheter, an intravascular pressure measurement method, and an intravascular pressure detection device that are capable of pressure measurement of a stenosed vessel.
The present disclosure relates to an intravascular pressure measurement catheter, comprising: a distal cannula having a guidewire lumen slidably receiving a separate medical guidewire; a proximal portion coupled with the distal cannula; a pressure sensor disposed within the lumen of the proximal portion and separating the lumen of the proximal portion into a measurement lumen, the measurement lumen in communication with the guidewire lumen of the distal cannula, the pressure sensor for measuring blood pressure of blood flowing into the measurement lumen and generating a blood pressure signal, and the proximal portion further comprising a signal path for transmitting the blood pressure signal from the pressure sensor.
The intravascular pressure measuring catheter provided by the disclosure can reduce the thickness of the distal sleeve and avoid forming a bulge, so that the distal sleeve can pass through a narrower lesion, the application range is widened, and the pushability of the pressure measuring catheter in a blood vessel is also increased. In addition, the pressure sensor is protected by the wall of the proximal end part, so that the influence on the pressure sensor during collision or bending of the pressure measuring catheter can be reduced, and the accuracy of blood pressure measurement can be improved.
In addition, in the intravascular pressure measurement catheter according to the present disclosure, optionally, the pressure sensor includes a sensing portion having a sensing region that senses pressure, and a lead portion that derives the blood pressure signal generated by the sensing region. Thus, the medical staff can read the measured blood pressure information through the external device after connecting the lead part to the external device through the signal path.
In addition, in the intravascular pressure measurement catheter according to the present disclosure, optionally, a quick exchange port for receiving the medical guidewire is provided at a sidewall of the distal cannula. In this case, the guide wire may guide the pressure measuring catheter through the quick-change port, whereby the intravascular pressure measuring catheter can be slid along the guide wire, thereby positioning the hose at a specific location within the patient's body, improving the surgical efficiency of the interventional procedure.
In addition, in the intravascular pressure measurement catheter according to the present disclosure, optionally, at least a young's modulus of the proximal portion where the pressure sensor is provided is larger than a young's modulus of the distal sleeve. In this case, the proximal end portion can better protect the pressure sensor, reducing the influence of the intravascular pressure measurement catheter on the compression of the pressure sensor due to deformation, whereby the measurement accuracy of the pressure sensing device can be ensured.
In addition, in the intravascular pressure measurement catheter according to the present disclosure, optionally, the pressure sensor is a thin film pressure sensor and forms an angle with a length direction of the proximal portion. Thus, the thin film pressure sensor can measure blood pressure at a proper angle.
In addition, in the intravascular pressure measurement catheter according to the present disclosure, optionally, an intermediate portion connecting the distal sleeve and the proximal portion is further included, the young's modulus of the intermediate portion being between the young's modulus of the distal sleeve and the young's modulus of the proximal portion. Thereby, the robustness of the intravascular pressure measuring catheter in the blood vessel can be increased, and the operation of a doctor is facilitated.
In addition, in the intravascular pressure measurement catheter according to the present disclosure, an outer tube covering the distal sleeve and the proximal portion may be optionally further provided. Thereby, the impact of the collision between the intravascular pressure measurement catheter and the vessel wall on the stability of the measurement catheter can be reduced before the pressure measurement catheter enters the coronary.
In addition, in the intravascular pressure measurement catheter according to the present disclosure, the included angle is optionally 45 ° to 135 °. This makes it possible to more accurately measure the blood pressure by making contact with the blood flow.
Additionally, in the intravascular pressure measurement catheter according to the present disclosure, optionally, the guidewire lumen slidably receives a medical guidewire having an outer diameter of about 0.2mm to 1 mm. Thereby, the type of receivable guide wire can be increased.
Additionally, in the intravascular pressure measurement catheter according to the present disclosure, optionally, the distal sleeve is coaxial with the proximal portion. Thereby, the stability of the intravascular pressure measurement catheter can be improved.
According to the intravascular pressure measuring catheter of the present invention, an intravascular pressure measuring catheter, an intravascular pressure measuring method, and an intravascular pressure detecting device that can measure the pressure of a stenosed blood vessel can be provided.
Drawings
Fig. 1 is a schematic cross-sectional view showing an intravascular pressure measurement catheter according to an embodiment of the present invention.
Fig. 2 is a schematic partial cross-sectional view showing an intravascular pressure measurement catheter according to an embodiment of the present invention.
Fig. 3 is a schematic partial cross-sectional view showing an intravascular pressure measurement catheter according to another embodiment of the present invention.
Fig. 4 is a schematic diagram showing the combination of the pressure sensor of the intravascular pressure measurement catheter according to the embodiment of the present invention and the pedestal.
Fig. 5 is a schematic view showing a lead portion of a pressure sensor of an intravascular pressure measurement catheter according to an embodiment of the present invention.
Description of the drawings:
1 … intravascular pressure measuring catheter, 2 … medical guide wire, 10 … distal sleeve, 20 … proximal portion, 30 … pressure sensor, 40 … pedestal, 11 … annular sleeve, 12 … outer tube, F … blood flow inflow direction, angle θ … pressure sensor to horizontal plane, 31 … sensing portion, 32 … lead portion, 32a, 32b, 32c … pins.
Detailed Description
Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. In the following description, the same members are denoted by the same reference numerals, and overlapping description thereof is omitted. In addition, the drawings are schematic, and the ratio of the sizes of the components to each other, the shapes of the components, and the like may be different from actual ones.
Fig. 1 is a schematic cross-sectional view showing an intravascular pressure measurement catheter 1 according to an embodiment of the present invention.
As shown in fig. 1, an intravascular pressure measurement catheter 1 (hereinafter, also referred to as simply "pressure measurement catheter 1", "blood pressure measurement catheter 1", "measurement catheter 1") includes a distal sleeve 10 having a guidewire lumen that slidably receives a separate medical guidewire 2 (hereinafter, also referred to as "guide guidewire 2", "guidewire 2"). A proximal portion 20 coupled to the distal cannula 10; a pressure sensor 30 disposed within the lumen of the proximal portion 20 and separating the lumen of the proximal portion 20 into a measurement lumen, the measurement lumen being in communication with the guidewire lumen of the distal cannula 10, the pressure sensor 30 for measuring blood pressure of blood flowing into the measurement lumen and generating a blood pressure signal, and the proximal portion 20 further comprising a signal path for transmitting the blood pressure signal from the pressure sensor 30.
The intravascular pressure measuring catheter 1 provided by the disclosure can reduce the thickness of the distal sleeve 10 so that the distal sleeve 10 does not have protrusions, therefore, the distal sleeve 10 can penetrate through narrower lesions, the application range is widened, the pushing performance of the pressure measuring catheter 1 in a blood vessel is further increased, the operation of a doctor is facilitated, and the operation time is saved. In addition, the pressure sensor 30 is protected by the wall of the proximal portion, so that the influence on the pressure sensor during collision or bending of the pressure measurement catheter 1 can be reduced, and the accuracy of blood pressure measurement can be improved.
In the blood pressure measuring catheter 1 according to the present embodiment, the distal sleeve 10 has a guidewire lumen. The guidewire lumen slidably receives a separate medical guidewire 2. Thus, by having the distal cannula 10 receive and slide along the medical guidewire 2, the distal cannula 10 and the pressure sensor 30 disposed on the proximal portion 20 can be delivered to a predetermined location within a patient (e.g., vein, artery). Thus, blood pressure measurements can be taken at the predetermined location (e.g., focal location) to obtain a Fractional Flow Reserve (FFR) reading at that location, providing a reference for subsequent interventions.
As described above, the value of Fractional Flow Reserve (FFR) (referred to as "FFR value") can be used to assess the extent to which stenotic lesions block blood flow through a blood vessel, providing a physician or the like with a decision as to whether to perform an interventional procedure. In general, to calculate the FFR value for a given stenosis, blood pressure readings of the distal side of the stenosis (e.g., downstream of the stenosis) and the proximal side of the stenosis (e.g., upstream of the stenosis, proximal to the aorta) need to be measured and acquired, respectively. The blood pressure gradient of a stenosis reflects an indication of the severity of the stenosis. The more severe the stenosis, the greater the pressure drop and the lower the FFR value.
In some examples, the guidewire lumen slidably receives a medical guidewire 2 having an outer diameter of about 0.2mm to 1 mm. Thereby, the type of receivable guide wire 2 can be increased.
In some examples, a quick-change port is provided in the sidewall of the distal sleeve 10 for receiving the medical guidewire 2. In this case, the guide wire 2 may guide the pressure measuring catheter 1 through the quick-change port, whereby the intravascular pressure measuring catheter 1 can slide along the guide wire 2, thereby positioning the hose to a specific position in the patient's body, improving the surgical efficiency of the interventional procedure.
In some examples, the Young's modulus of at least the proximal portion 20 provided with the pressure sensor 30 is greater than the Young's modulus of the distal cannula 10. In this case, the proximal end portion 20 can better protect the pressure sensor 30, reducing the pressing of the intravascular pressure measuring catheter 1 against the pressure sensor 30 due to deformation, whereby the measurement accuracy of the pressure sensing device can be ensured.
In some examples, further comprising an intermediate portion connecting the distal cannula 10 and the proximal portion 20, the young's modulus of the intermediate portion being between the young's modulus of the distal cannula 10 and the young's modulus of the proximal portion 20. Thereby, the robustness of the intravascular pressure measuring catheter 1 in the blood vessel can be increased, facilitating the operation by the physician.
In some examples, the material of construction of the proximal portion 20 is not particularly limited, and a higher durometer material is preferred to ensure that the physician can advance the distal sleeve 10 along the medical guidewire 2 into the patient's vessel during the interventional procedure through the proximal portion 20 to locate the stenotic lesion.
In some examples, the proximal portion 20 may be stiffer and more rigid than the distal cannula 10 to enable better movement and advancement of the distal cannula 10. In some examples, the proximal portion 20 may be constructed of medical grade stainless steel. In other examples, the proximal portion 20 may also be constructed of other materials such as nitinol, nylon, plastic, polyimide (PI), and the like.
In some examples, pressure sensor 30 includes a sensing portion 31 and a lead portion 32, sensing portion 31 having a sensing region that senses pressure, lead portion 32 deriving a blood pressure signal generated by the sensing region through pins (32 a, 32b, 32 c). Thus, the medical staff can read the measured blood pressure information through the external device after connecting the lead part to the external device through the signal path.
In some examples, the signal path may be communicated to a device located external to the patient, such as a processor, display, computer, monitor, or the like.
In some examples, an outer tube 12 is also provided that encases the distal sleeve 10 and the proximal portion 20. Thereby, the impact of the collision between the intravascular pressure measurement catheter 1 and the vessel wall on the stability of the measurement catheter 1 can be reduced before the pressure measurement catheter 1 enters the coronary artery.
In addition, in some examples, an annular sleeve 11 may also be provided at the front end of the distal sleeve 10 as a locating indicator. The annular sleeve 11 is flexible and comprises a material that is opaque to X-rays. In other examples, the annular sleeve 11 may be flexible. Thus, when the blood pressure measuring catheter 1 moves in the blood vessel of the patient, the damage to the blood vessel can be reduced.
In the present embodiment, as described above, during the interventional procedure, it is necessary to move the distal cannula 10 by manipulating the proximal portion 20 (specifically, connecting the blood pressure measuring catheter 1). When moving or adjusting the distal cannula 10 within a blood vessel along the medical guidewire 2, the distal cannula 10 may touch the blood vessel or a site of greater curvature of the blood vessel near the distal cannula 10. In this case, even when the distal end sleeve 10 slides along the medical guidewire 2 to contact a nearby blood vessel, the annular sleeve 11 provided at the forefront end of the distal end sleeve 10 has flexibility, and thus damage to the blood vessel can be reduced.
In the present embodiment, since the annular tube 11 includes a material opaque to X-rays, the annular tube 11 can form an opaque pattern when a human body is irradiated with X-rays. Through the opaque pattern, a doctor or the like can quickly find the corresponding positioning mark.
In some examples, the outer peripheral surface of the outer tube 12 is preferably tangential to the annular sleeve 11, whereby the operability of the distal sleeve 10 and the annular sleeve 11 can be improved. The material of the outer tube 12 may be polyester, polyamide, nylon elastomer, polyurethane, polyimide (PI), or the like.
In other examples, the outer tube 12 may be part of the molding process of the distal cannula 10. The outer tube 12 is tightly connected to the distal cannula 10, for example, by using welding. Alternatively, the guidewire lumen of the distal cannula 10 may be formed by hot melt molding.
Fig. 2 is a schematic partial cross-sectional view showing an intravascular pressure measurement catheter 1 according to an embodiment of the present invention. Fig. 3 is a schematic partial cross-sectional view showing an intravascular pressure measurement catheter 1 according to another embodiment of the present invention. Fig. 4 is a schematic diagram showing the combination of the pressure sensor 30 and the pedestal 40 of the intravascular pressure measurement catheter 1 according to the embodiment of the present invention.
Fig. 5 is a schematic view showing a lead portion 32 of the pressure sensor 30 of the intravascular pressure measurement catheter 1 according to the embodiment of the present invention.
In some examples, a pressure sensor 30 is disposed at the proximal portion 20. Blood flow flows through the distal cannula 10 into the proximal portion 20 and contacts the pressure sensor 30, and the pressure sensor 30 (and more specifically the measurement site of the pressure sensor 30) is capable of sensing and/or measuring intravascular blood pressure of the patient and generating a blood pressure signal. The pressure sensor 30 is connected to a signal path, and a blood pressure signal generated by the pressure sensor 30 is transmitted to, for example, an extracorporeal processing device (not shown) via the signal path.
In some examples, pressure sensor 30 may be a thin film pressure sensor and form an angle θ with the length of proximal portion 20. Thus, the thin film pressure sensor 30 can measure the blood pressure at an appropriate angle.
In some examples, the included angle θ is 45 ° to 135 °. This makes it possible to more accurately measure the blood pressure by making contact with the blood flow.
As shown in fig. 2, blood flows in the direction indicated by the arrow, and the pressure sensor 30 can measure the pressure of the blood flow flowing in the direction F. In other examples, pressure sensor 30 may form an angle θ with horizontal plane L1 in the L2 direction, which may be between 45 ° and 135 °.
In other examples, as shown in fig. 3, the pressure sensor 30 may be positioned tangentially to the quick-change port. In this case, blood can flow out from the quick-change port along the pressure sensor 30, reducing the influence of blood reflux on blood pressure measurement, thereby improving the accuracy of blood pressure measurement.
Additionally, in some examples, the pressure sensor 30 may be a capacitive pressure sensor, a resistive pressure sensor, or the like. The pressure sensor 30 may be a MEMS pressure sensor. For example, the pressure sensor 30 may measure in the range of about-50 mm Hg to about +300 mm Hg. Depending on the type of pressure sensor 30, the signal path may be an electrically conductive medium such as an electrical lead. Further, in some embodiments, the signal path may also be a wireless communication line, an infrared communication line, or an ultrasonic communication line.
As shown in fig. 4, 5, in some examples, the proximal portion 20 may also be provided with a stand 40 for supporting the pressure sensor 30, with the lead portion 32 of the pressure sensor 30 being combined with the stand 40, and the sensing portion 31 for measuring blood flow pressure. In some examples, the pedestal 40 may be an alloy of one or more of cobalt-chromium alloy, titanium alloy, aluminum alloy, or stainless steel, or a composite of any of the above. In addition, the bracket can also be made of hard engineering plastics such as ABS, PMMA, PET, has enough flexural strength and can effectively inhibit the stress deformation of the bracket.
In other examples, abutment 40 may be secured within the lumen of proximal portion 20 by welding, interlocking, adhesive, or the like.
Additionally, in some examples, the abutment 40 may be correspondingly configured according to the shape of the proximal portion 20 to provide accurate data results to the physician, such that the pressure sensor 30 may measure the pressure of the intravascular blood without impact, and more accurately measure the blood pressure value.
In some examples, the pressure sensor 30 may be secured without the use of the abutment 40, and the pressure sensor 30 may be disposed directly within the lumen of the proximal portion 20. Thus, the pressure sensor 30 can directly receive the pressure of the intravascular blood, without being affected by the pedestal 40.
In other examples, a gel may also be filled between the pressure sensor 30 and the proximal portion 20. Specifically, for example, medical silicone gel can be filled, whereby penetration of liquid such as blood into the lead portion 32 can be avoided, and the reliability of the pressure sensor 30 and the signal path for transmitting the blood pressure signal can be improved. Moreover, the silicone gel may also provide cushioning for the pressure sensor 30.
Generally, during interventional therapy, an operator such as a doctor first advances a medical guide wire 2 from a certain site (e.g., at a femoral artery) of a patient along a blood vessel to, for example, a coronary artery of a heart, then finds a position of the blood vessel where a lesion may occur by, for example, contrast agent imaging, and advances a blood pressure measuring catheter 1 to a predetermined position along the medical guide wire 2. In this case, the blood pressure measuring catheter 1 is passed over the medical guidewire 2 by threading the distal cannula 10 onto the medical guidewire 2 (see fig.), such that the guidewire lumen slides over the medical guidewire 2, and the distal cannula 10 (and the pressure sensor 30 provided on the distal cannula 10) is moved by operating (e.g. pushing and/or pulling) the connecting blood pressure measuring catheter 1 (or an operating device (not shown) connected to the connecting blood pressure measuring catheter 1) outside the patient until the pressure sensor 30 is in a predetermined position.
In some examples, the distal cannula 10 is coaxial with the proximal portion 20. This can improve the stability of the intravascular pressure measurement catheter 1.
In some examples, since the distal sleeve 10 is moved along the medical guidewire 2 to be delivered to a predetermined location within a patient's blood vessel, repositioning of the medical guidewire 2 is not required in operating the blood pressure measurement catheter 1 in accordance with embodiments of the present invention.
Specifically, for example, when the pressure sensor 30 on the blood pressure measurement catheter 1 is positioned at the distal end of the stenosis (e.g., downstream of the stenosis), the blood pressure at the distal side of the stenosis is measured first. Next, the pressure sensor 30 can be brought to the proximal side of the stenosis by moving (e.g., advancing and/or retracting) the distal cannula 10 without adjusting the position of the medical guidewire 2, whereby blood pressure readings of the distal and proximal ends of the stenosis can be taken without moving the medical guidewire 2. Therefore, the surgical complexity of interventional therapy can be reduced and the surgical time can be saved.
While the invention has been described in detail in connection with the drawings and embodiments, it should be understood that the foregoing description is not intended to limit the invention in any way. Modifications and variations of the invention may be made as desired by those skilled in the art without departing from the true spirit and scope of the invention, and such modifications and variations fall within the scope of the invention.

Claims (10)

1. A blood pressure measurement catheter, comprising:
a distal cannula, a proximal portion and a pressure sensor; the distal cannula having a guidewire lumen;
the proximal portion is coupled to the distal sleeve;
the pressure sensor is disposed within the lumen of the proximal portion and separates the lumen of the proximal portion into a measurement lumen, the measurement lumen in communication with the guidewire lumen of the distal cannula, the pressure sensor for measuring blood pressure of blood flowing into the measurement lumen via the distal cannula and generating a blood pressure signal.
2. The blood pressure measuring catheter of claim 1,
the guidewire lumen slidably receives a separate medical guidewire.
3. The blood pressure measuring catheter of claim 2,
at the side wall of the distal cannula, a quick exchange port is provided for receiving the medical guidewire.
4. A blood pressure measuring catheter according to claim 3, wherein,
the pressure sensor is arranged at a position tangential to the rapid exchange port.
5. The blood pressure measuring catheter of claim 1,
the front end of the distal sleeve is also provided with an annular sleeve serving as a positioning mark.
6. The blood pressure measuring catheter of claim 5,
the annular sleeve is flexible and comprises a material that is opaque to X-rays.
7. The blood pressure measuring catheter of claim 1,
an outer tube is also provided that encases the distal sleeve and the proximal portion.
8. The blood pressure measuring catheter of claim 7,
the outer peripheral surface of the outer tube is tangential to the annular sleeve.
9. The blood pressure measuring catheter of claim 1,
a gel is filled between the pressure sensor and the proximal portion.
10. The blood pressure measuring catheter of claim 1,
the distal sleeve is coaxial with the proximal portion.
CN202311375097.XA 2019-08-02 2019-08-02 blood pressure measuring catheter Pending CN117582193A (en)

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CN201910710109.7A CN112294278B (en) 2019-08-02 2019-08-02 Intravascular pressure measuring catheter

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