CN117581876A

CN117581876A - Herbicide and application thereof

Info

Publication number: CN117581876A
Application number: CN202311539011.2A
Authority: CN
Inventors: 孙运迎; 李丹; 占玉萍; 薛进春; 张聪; 路军; 茹李军; 王磊
Original assignee: Beijing Nutrichem Co ltd
Current assignee: Beijing Nutrichem Co ltd
Priority date: 2023-11-17
Filing date: 2023-11-17
Publication date: 2024-02-23

Abstract

The invention provides a herbicide and application thereof, and relates to the technical field of pesticides, wherein the active ingredients of the herbicide comprise Epyrifenacil and terbuthylazine; wherein, the weight ratio of Epyrifenacin to terbuthylazine is 1:0.01 to 1000. The invention solves the problem of aggravated rising trend of drug-resistant weeds in the current farmland, and achieves the technical effects of broad herbicide control spectrum, remarkable weed control effect, delay of weed resistance, low dosage of herbicide, low medication cost and environmental safety.

Description

Herbicide and application thereof

Technical Field

The invention relates to the technical field of pesticides, in particular to a herbicide and application thereof.

Background

Farmland weeds are important factors causing the reduction of crop yield and quality, and the farmland weeds compete with crops for soil nutrients, space, illumination and the like to directly harm the crops, and simultaneously serve as hosts of pathogenic bacteria and insects to indirectly harm the crops.

The popularization and use of high-efficiency chemical herbicides on a large scale brings benefits to agricultural production, and at the same time, the problem of weed drug resistance is also caused, and the method also becomes a global challenge. In recent years, the number of resistant weeds is nearly in a straight line rising trend, if the resistant weeds are not controlled, after the resistant weeds are evolved into dominant species of farmlands, the damage of the farmland weeds can be aggravated, and the difficulty of preventing and removing the farmland weeds can be increased.

In view of this, the present invention has been made.

Disclosure of Invention

One of the purposes of the invention is to provide a herbicide which can show excellent synergism, has wide herbicidal spectrum and remarkable weed control effect, and can effectively reduce the dosage of pesticides, thereby reducing the cost of the pesticides and the degree of influence on the environment.

The second purpose of the invention is to provide an application of the herbicide, which can simultaneously control various weeds, is convenient and efficient to use and has outstanding application effect.

In order to achieve the above object of the present invention, the following technical solutions are specifically adopted:

in a first aspect, a herbicide, the active ingredients of which include ephifenacin and terbuthylazine;

wherein, the weight ratio of the Epyrifenacin to the terbuthylazine is 1:0.01 to 1000.

Further, the weight ratio of the Epyrifenacin to the terbuthylazine is 1:0.1 to 500;

preferably, the weight ratio of the Epyrifenacin to the terbuthylazine is 1:1 to 500;

preferably, the weight ratio of the Epyrifenacin to the terbuthylazine is 1:2 to 300 percent.

Further, the weight ratio of the active ingredient in the herbicide is 1-99%;

preferably, the weight ratio of the active ingredient in the herbicide is 5-70%.

Further, the weight ratio of the active ingredient in the herbicide is 10-50%.

Further, the herbicide also comprises at least one of an agropharmaceutically acceptable surfactant and a carrier.

Further, the dosage form of the herbicide comprises at least one of emulsifiable concentrate, aqueous emulsion, aqueous suspension, suspending emulsion, dispersible oil suspension, wettable powder and water dispersible granule.

In a second aspect, the use of a herbicide as defined in any one of the preceding claims for controlling grassy weeds and broadleaf weeds.

Further, the herbicide is applied to prevention and treatment of grassy weeds and broadleaf weeds in corn fields.

Further, the weeds include at least one of green bristlegrass, barnyard grass, crab grass, goosefoot, moleplant seed, dayflower, purslane, japanese thistle, quinoa, amaranth, and spiny.

Further, the weeds are at least one of green bristlegrass, crabgrass, purslane and amaranth.

Compared with the prior art, the invention has at least the following beneficial effects:

the herbicide provided by the invention is used by compounding Epyrifenacin and terbuthylazine agents with different structure types and different action mechanisms, so that the weeding characteristics of the Epyrifenacin and terbuthylazine agents are complemented with each other to effectively delay the occurrence and development of resistance of weeds to single agents, and an excellent synergistic effect can be generated, and particularly, compared with the single agents, the Epyrifenacin and terbuthylazine agents can show an excellent synergistic effect, thereby obviously improving the weeding effect, reducing the pesticide dosage and lowering the medication cost of farmers and the influence degree on the environment; the Epyrafenacil and terbuthylazine in the herbicide disclosed by the invention can play a remarkable synergistic effect, so that the prevention and removal effects on annual and perennial grassy weeds and broadleaf weeds can be improved to a greater extent, and the weed control spectrum of the two components of the Epyrafenacil and terbuthylazine serving as single components is enlarged.

The herbicide provided by the invention can be used for simultaneously controlling various weeds, has a broad herbicide controlling spectrum, is convenient and efficient to use, and has low application dosage and small influence degree on the environment, so that the application effect is outstanding.

Detailed Description

The technical solutions of the present invention will be clearly and completely described in connection with the embodiments, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

According to a first aspect of the present invention there is provided a herbicide whose active ingredients include ephifenacin and terbuthylazine;

wherein, the weight ratio of Epyrifenacin to terbuthylazine is 1:0.01 to 1000.

Epyrifenacin is a uracil herbicide developed by Sumitomo chemical Co., ltd.) and has the mechanism of action of protoporphyrinogen oxidase (PPO) inhibitor herbicides, chemical name: [ (3- { 2-chloro-5- [3, 6-dihydro-3-methyl-2, 6-dioxo-4- (trifluoromethyl) pyrimidin-1 (2H) -yl]-4-fluorophenoxy } -2-pyridine) oxy]Ethyl acetate; CAS accession number: 353292-31-6; the molecular formula: c (C) ₂₁ H ₁₆ ClF ₄ N ₃ O ₆ 。

Terbuthylazine belongs to triazine inhibitors, and the English generic name is terbutylazine, and the chemical name is: N2-tert-butyl-6-chloro-N4-ethylidene-1, 3, 5-triazine-2, 4-diamine with CAS registry number 5915-41-3, molecular formula C ₉ H ₁₆ Cl N ₅ 。

In the present invention, typical but non-limiting weight ratios of Epyrifenacin and terbuthylazine are for example 1:0.01, 1:0.1, 1: 1. 1: 2. 1: 3. 1: 4. 1: 5. 1: 10. 1: 20. 1: 30. 1: 40. 1: 50. 1: 60. 1: 70. 1: 80. 1: 90. 1: 100. 1: 150. 1: 200. 1: 250. 1: 300. 1: 350. 1: 400. 1: 450. 1: 500. 1: 550. 1: 600. 1: 650. 1: 700. 1: 750. 1: 800. 1: 850. 1: 900. 1: 950. 1:1000.

in a preferred embodiment, the weight ratio of ephrimenacil to terbuthylazine may be 1:0.1 to 500, which is more favorable for further improving the synergy of Epyrifenacin and terbuthylazine, can be more preferably 1:1 to 500, more preferably 1:2 to 300 percent.

In the present invention, the content of the active ingredient in the herbicide may vary widely.

In a preferred embodiment, the weight ratio of active ingredient in the herbicide may be 1-99%, with typical but non-limiting weight ratios of, for example, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 96%, 97%, 99%, and any two of the numerical ranges described above.

In a preferred embodiment, the weight ratio of the active ingredient in the herbicide may be from 5 to 70%, more advantageously further improving the herbicidal effect against annual and perennial grasses and broadleaf weeds, still more preferably from 10 to 50%.

In a preferred embodiment, the herbicide may contain at least one of an agropharmaceutically acceptable surfactant and carrier in addition to the active ingredient.

The surfactant in the present invention is not particularly limited, and may be, for example, various surfactants known in the field of agricultural chemical formulation, and may be further preferably one or more of an emulsifier, a dispersant and a wetting agent.

The emulsifier can be various emulsifiers known in the pesticide formulation field, and concretely, the emulsifier in the invention can be one or more of calcium dodecyl benzene sulfonate, triphenyl ethyl phenol polyoxyethylene ether phosphate, fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene polyoxypropylene ether, fatty amine, ethylene oxide adduct of fatty amide, fatty acid polyoxyethylene ester, abietic acid ethylene oxide adduct, polyol fatty acid ester and ethylene oxide adduct thereof, styrylphenyl polyoxyethylene ether, alkylphenol formaldehyde resin polyoxyethylene ether, hydroxyl-terminated polyoxyethylene polyoxypropylene ether, styrylphenol formaldehyde resin, polyoxyethylene polyoxypropylene ether and castor oil polyoxyethylene ether. The dispersing agent can be various dispersing agents known in the pesticide formulation field, and concretely, the dispersing agent in the invention can be one or more of acrylic acid copolymer sodium salt, maleic acid disodium salt, naphthalene sulfonic acid formaldehyde condensate sodium salt, rosin block polyoxyethylene ether polyoxypropylene ether sulfonate, hydroxyl-terminated polyoxyethylene polyoxypropylene ether block copolymer, triphenyl ethyl phenol polyoxyethylene ether phosphate, fatty alcohol polyoxyethylene ether phosphate, sodium p-hydroxyphenyl lignin sulfonate and calcium lignin sulfonate. The wetting agent can be various wetting agents known in the pesticide formulation field, and concretely, the wetting agent in the invention can be one or more of sodium dodecyl sulfate, secondary sodium alkyl sulfate, sodium dodecyl benzene sulfonate, fatty alcohol polyoxyethylene ether, alkyl naphthalene sulfonate and alkylphenol resin polyoxyethylene ether sulfate.

The carrier in the present invention is not particularly limited, and may be, for example, various carriers known in the field of agricultural chemical formulation, including, but not limited to, various silicates, carbonates, sulfates, oxides, phosphates, plant carriers, and synthetic carriers; specifically, the carrier in the present invention may be, for example, one or more of white carbon black, kaolin, diatomaceous earth, clay, talc, organobentonite, pumice, titanium dioxide, dextrin, cellulose powder, light calcium carbonate, soluble starch, corn starch, sawdust powder, urea, an amine fertilizer, a mixture of urea and an amine fertilizer, glucose, maltose, sucrose, anhydrous potassium carbonate, anhydrous sodium carbonate, anhydrous potassium bicarbonate, anhydrous sodium bicarbonate, attapulgite, a mixture of anhydrous potassium carbonate and anhydrous potassium bicarbonate, and a mixture of anhydrous sodium carbonate and anhydrous sodium bicarbonate.

In a preferred embodiment, the herbicide may further contain various adjuvants for formulation commonly used in the field of agricultural chemical formulation, and specifically, the adjuvants for formulation in the present invention may be, for example, one or more of solvents, co-solvents, thickeners, antifreezes, protectants, antifoaming agents, disintegrants, stabilizers, preservatives, and binders.

In the present invention, the solvent may be various solvents well known in the field of agricultural chemical formulation, and specifically, the solvent in the present invention may be, for example, one or more of an organic solvent, a vegetable oil, a mineral oil, a solvent oil, and water. Wherein the organic solvent includes, but is not limited to, one or more of N-methylpyrrolidone, tetrahydrofuran, dimethyl sulfoxide, N-dimethyldecanoamide, N-dimethylformamide, trimethylbenzene, tetramethylbenzene, xylene, toluene, octane, heptane, methanol, isopropanol, N-butanol, tetrahydrofurfuryl alcohol, tributyl phosphate, 1, 4-dioxane, and cyclohexanone; vegetable oils include, but are not limited to, one or more of methylated vegetable oils, turpentine-based vegetable oils, epoxidized soybean oil, peanut oil, rapeseed oil, castor oil, corn oil, and pine seed oil; mineral oils include, but are not limited to, one or more of liquid waxes, motor oils, kerosene, and lubricating oils; meanwhile, the solvent can also be used as a cosolvent.

In the present invention, the antifreezing agent may be various antifreezing agents known in the field of pesticide dosage forms, and the antifreezing agent of the present invention may be further preferably one or more of ethylene glycol, propylene glycol, glycerin and urea; the thickener can be various thickeners known in the pesticide formulation field, specifically, the thickener can be one or more of xanthan gum, polyvinyl alcohol, polyacrylate alcohol, polyethylene glycol, white carbon black, diatomite, kaolin, clay, sodium alginate, aluminum magnesium silicate, sodium aluminum silicate, carboxymethyl cellulose, hydroxypropyl cellulose sodium and organic bentonite; the defoamer can be various defoamers known in the pesticide formulation field, and the defoamer can be one or more of organic siloxane, tributyl phosphate and silicone; the stabilizer can be selected from one or more of triphenyl phosphite, epichlorohydrin and acetic anhydride; the preservative may be selected from one or more of benzoic acid, sodium benzoate, 1, 2-benzisothiazolin-3-one (BIT for short), pinocembrane and potassium sorbate.

In a preferred embodiment, the dosage form of the herbicide may be various dosage forms commonly used in the art, including but not limited to at least one of emulsifiable concentrates, aqueous emulsions, aqueous suspensions, suspoemulsions, dispersible oil suspensions, wettable powders and water dispersible granules. The above dosage forms can be prepared by methods conventional in the art, and the present invention is not particularly limited thereto.

In a preferred embodiment, the emulsifiable concentrate formulation comprises the following components in weight percent:

1-95% of active ingredient, 0-20% of cosolvent, 1-30% of emulsifier and the balance of solvent to 100%.

The preparation method of the emulsifiable concentrate preparation can comprise the following steps: mixing and stirring the active ingredients, the solvent, the cosolvent and the emulsifier to form a uniform transparent oil phase, thus obtaining the emulsifiable concentrate preparation.

In a preferred embodiment, the aqueous emulsion or microemulsion comprises the following components in weight percent:

1-95% of active ingredient, 1-30% of emulsifying agent, 0-30% of cosolvent, 1-30% of solvent, 0-10% of antifreezing agent, 0-10% of thickening agent and water which are added to 100%.

The preparation method of the aqueous emulsion can comprise the following steps: mixing the active ingredient, the emulsifier, the cosolvent and the solvent to form a uniform oil phase; mixing water, a thickener and an antifreezing agent to form a uniform water phase; under high-speed shearing, adding the water phase into the oil phase or adding the oil phase into the water phase to form the aqueous emulsion with good dispersibility.

In a preferred embodiment, the aqueous suspension comprises the following components in weight percent:

1 to 95 percent of active ingredient, 1 to 30 percent of surfactant, 1 to 10 percent of antifreezing agent, 0.1 to 5 percent of thickening agent and the balance of water to 100 percent.

The preparation method of the water suspending agent can comprise the following steps: adding active ingredients, a surfactant, an auxiliary agent and the like into a sanding kettle by taking water as a medium, grinding to a certain particle size, and filtering; and adding the metered thickener into the ground mother solution, and shearing and dispersing uniformly to prepare the water suspending agent.

In a preferred embodiment, the water dispersible granule or wettable powder comprises the following components in percentage by weight:

1-95% of active ingredient, 1-30% of surfactant and the balance of other carriers to 100%.

The preparation method of the water dispersible granule can comprise the following steps: uniformly mixing active ingredients, a dispersing agent, a wetting agent, a carrier and the like, crushing to a certain particle size through air flow, adding water for kneading, finally adding into a granulator for granulating, and drying to obtain water dispersible granules or soluble granules.

The preparation method of the wettable powder can comprise the following steps: mixing the active ingredients, various auxiliary agents and other fillers such as carriers, and pulverizing with an ultrafine pulverizer.

The herbicide disclosed by the invention is prepared by compounding Epyrifenacin and terbuthylazine as components, has an obvious synergistic effect, can improve the preventing and killing effects of the two components on annual and perennial gramineae and broadleaf weeds to a greater extent, and simultaneously expands the weed killing spectrum of the two components when the two components are used as single active components; the herbicide disclosed by the invention combines active ingredients with different action mechanisms, so that the weeding characteristics of the ingredients are well complemented, the occurrence and development of resistance of weeds to single agents can be effectively delayed, various weeds can be prevented and treated simultaneously, the herbicide is convenient and efficient to use, the weeding effect is obviously improved, the dosage is reduced, and the application cost of farmers and the influence degree on the environment are reduced.

The herbicides of the invention may be provided in finished formulations, i.e. the substances are already mixed, or may be provided in separate formulations, which are self-mixed in a tank or canister prior to use and optionally diluted with water depending on the concentration of active substance required. In addition, the herbicide of the invention can be mixed with other compounds with bactericidal, insecticidal or herbicidal properties, and can also be mixed with nematicides, protective agents, growth regulators, plant nutrients or soil conditioners.

According to a second aspect of the present invention there is provided the use of a herbicide as defined in any one of the preceding claims for controlling grassy weeds and broadleaf weeds.

The herbicide disclosed by the invention can effectively control annual and perennial grasses and broadleaf weeds, and further can effectively control annual and perennial grasses and broadleaf weeds in corn fields.

In a preferred embodiment, the weed may be at least one of green bristlegrass, barnyard grass, crabgrass, goosegrass, moleplant seed, dayflower, purslane, japanese thistle, quinoa, amaranth, and spiny.

The inventor has unexpectedly found that the herbicide has extremely remarkable control effect on green bristlegrass, crabgrass, purslane and amaranthus retroflexus, and has high safety on crops (such as corn).

In the 3-5 leaf period of corn and the 2-5 leaf period of weed, the herbicide of the invention is sprayed on the whole field stem and leaf in corn field, and the stem and leaf spraying method is simple. Meanwhile, the application amount of the herbicide can slow down the influence of weather through a proper dosage form.

Therefore, the herbicide provided by the invention can be used for simultaneously preventing and treating various weeds, has a broad weed control spectrum, is convenient and efficient to use, and has low application dosage and small influence degree on the environment, so that the application effect is outstanding.

The invention is further illustrated by the following examples. The materials in the examples were prepared according to the existing methods or were directly commercially available unless otherwise specified. The Epyrifenacin original drug is self-made (purity is 95% by weight); terbuthylazine is commercially available (purity 97% by weight).

Example 1

A herbicide is a dispersible oil suspending agent, wherein the active ingredients are Epyrifenacin and terbuthylazine, and the weight ratio of the active ingredients is 15%.

The specific formula of the herbicide is as follows:

50g of Epyrifenacin, 100g of terbuthylazine, 60g of castor oil polyoxyethylene ether (40), 50g of triphenyl ethyl phenol polyoxyethylene ether phosphate, 40g of white carbon black and 1000g of methyl oleate.

The preparation method of the herbicide comprises the following steps:

methyl oleate is used as a medium, epyrifenacin, terbuthylazine, castor oil polyoxyethylene ether (40), triphenyl polyoxyethylene ether phosphate and white carbon black are added into a sanding kettle according to a proportion, and the mixture is ground to obtain the dispersible oil suspending agent containing 15 weight percent of active ingredients.

Example 2

A herbicide is a suspending agent, wherein the active ingredients are Epyrifenacin and terbuthylazine, and the weight ratio of the active ingredients is 30.1%.

The specific formula of the herbicide is as follows:

epyrifenacin 1g, terbuthylazine 300g, rosin block polyoxyethylene ether polyoxypropylene ether sulfonate 30g, polycarboxylate 40g, ethylene glycol 60g, white carbon black 60g, organosilicon defoamer 10g, and water to 1000g.

The preparation method of the herbicide comprises the following steps:

water is used as a medium, epyrifenacin, terbuthylazine, rosin block polyoxyethylene ether polyoxypropylene ether sulfonate, polycarboxylate, glycol, white carbon black, an organosilicon defoamer and water are added into a shearing kettle in proportion, and the mixture is uniformly sheared and then placed into a sanding kettle for grinding, so that the suspending agent containing 30.1 weight percent of active ingredients is obtained.

Example 3

A herbicide is a suspension emulsion, wherein the active ingredients are Epyrifenacin and terbuthylazine, and the weight ratio of the active ingredients is 21%.

The specific formula of the herbicide is as follows:

10g of Epyrifenacin, 200g of terbuthylazine, 250g of N-methyl pyrrolidone, 30g of sodium dodecyl benzene sulfonate, 40g of castor oil polyoxyethylene ether (20), 30g of xanthan gum and 60g of glycerol, and the water is added to 1000g.

The preparation method of the herbicide comprises the following steps:

adding terbuthylazine, sodium dodecyl benzene sulfonate, castor oil polyoxyethylene ether (20), xanthan gum and glycerol into a sanding kettle to grind to obtain a terbutryn Ding Jinshui suspending agent;

mixing Epyrifenacil, N-methylpyrrolidone, sodium dodecyl benzene sulfonate and castor oil polyoxyethylene ether (20) thoroughly to obtain an oil phase;

the oil phase was added to the terbuthylazine suspension to obtain a suspoemulsion containing 21 wt% active ingredient.

Example 4

A herbicide is water dispersible granule, wherein the active ingredients are Epyrifenacin and terbuthylazine, and the weight ratio of the active ingredients is 51%.

The specific formula of the herbicide is as follows:

10g of Epyrifenacin, 500g of terbuthylazine, 120g of rosin block polyoxyethylene ether polyoxypropylene ether sulfonate, 60g of alkylphenol resin polyoxyethylene ether sulfate, 80g of starch and 1000g of kieselguhr.

The preparation method of the herbicide comprises the following steps:

epyrifenacin, terbuthylazine, rosin block polyoxyethylene ether polyoxypropylene ether sulfonate, alkylphenol resin polyoxyethylene ether sulfate, starch and diatomite are mixed and crushed according to a certain proportion, and extruded and granulated to obtain the water-dispersible granule containing 51 weight percent of active ingredients.

Example 5

A herbicide is wettable powder, wherein the active ingredients are Epyrifenacin and terbuthylazine, and the weight ratio of the active ingredients is 81%.

The specific formula of the herbicide is as follows:

10g of Epyrifenacin, 800g of terbuthylazine, 50g of hydroxyl-terminated polyoxyethylene polyoxypropylene ether block copolymer, 60g of sodium lignin sulfonate, 20g of white carbon black and 1000g of kaolin.

The preparation method of the herbicide comprises the following steps:

epyrifenacin, terbuthylazine, hydroxyl-terminated polyoxyethylene polyoxypropylene ether block copolymer, sodium lignin sulfonate, white carbon black and kaolin are mixed and crushed according to a certain proportion to prepare the wettable powder containing 81 weight percent of active ingredients.

Example 6

A herbicide is emulsifiable concentrate, wherein the active ingredients are Epyrifenacin and terbuthylazine, and the weight ratio of the active ingredients is 20.2%.

The specific formula of the herbicide is as follows:

epyrifenacin 2g, terbuthylazine 200g, dimethyl sulfoxide (solvent) 200g, castor oil polyoxyethylene ether (40) (emulsifier) 30g, calcium dodecyl sulfate 70g, and solvent oil 200# (solvent) 1kg.

The preparation method of the herbicide comprises the following steps:

epyrifenacin, terbuthylazine, dimethyl sulfoxide, castor oil polyoxyethylene ether (40), calcium dodecyl sulfonate and solvent oil 200# are mixed according to a certain proportion to form a uniform oil phase, so as to obtain the emulsifiable concentrate containing 20.2 weight percent of active ingredients.

Examples 7 to 10

Examples 7-10 differ from example 3 in that the weight ratios of Epyrifenacin and terbuthylazine in examples 7-10 are 1:0.01, 1:0.1, 1: 1. 1:10, the remainder were the same as in example 3 to obtain herbicides.

Examples 11 to 15

Examples 11 to 15 differ from example 3 in that the weight ratio of Epyrifenacin to terbuthylazine in examples 11 to 15 is 1: 200. 1: 400. 1: 600. 1: 800. 1:1000, the remainder were the same as in example 3, giving herbicides.

Comparative example 1

The comparative example provides a herbicide, which is a suspending agent, wherein the active ingredient of the herbicide is only Epyrifenacin, and the weight ratio of the active ingredient is 30%.

Comparative example 2

The comparative example provides a herbicide, which is a suspending agent, wherein the active ingredient of the herbicide is terbuthylazine only, and the weight ratio of the active ingredient is 50%.

Comparative example 3

The difference between this comparative example and example 3 is that the weight ratio of Epyrifenacin to terbuthylazine is 1:0.005, the remainder were the same as in example 3, to obtain a herbicide.

Comparative example 4

The difference between this comparative example and example 3 is that the weight ratio of Epyrifenacin to terbuthylazine is 1:1500, and the remainder were the same as in example 3, to obtain a herbicide.

Test example 1

The herbicides of examples 1 to 15 and comparative examples 1 to 4 were tested for field herbicidal effect. The application method comprises the following steps: the corn variety is Zhengdan 958, and the test site is Zhengfeizhou Yingcun village of Beijing city in the sense area Zhao Quanying; spraying the stems and leaves for 1 time in the 4-leaf period and the 2-4-leaf period of the corn, wherein the field spraying amount is 30L/mu, and the pesticide applying device is a backpack electric sprayer manufactured by singapore private limited company, and the model is Jactopjb-16; setting 8 treatments, repeating for 4 times, randomly arranging test cells, and controlling cell area to 20m ² The method comprises the steps of carrying out a first treatment on the surface of the On day 21 after administration, 4 0.25m cells were randomly selected per cell ² Investigation of fresh weights of all weeds, and calculation of fresh weight control effects of the weeds according to a formula;

the control effect calculating method comprises the following steps:

wherein: PT-agent treatment zone fresh weight; fresh weight of CK-blank control zone;

efficacy results: under the condition of the test amount, the herbicide of the examples 1-15 has good preventing and killing effects on gramineae and broadleaf weeds in fields after 21d of application;

the specific results are shown in the following table.

Fresh weight control Effect of the herbicides of examples and comparative examples on corn field weeds

Test example 2

Reference is made to NY/T1155.4-2006, spray method for determining the activity of the 4 th part of the herbicide according to the biological assay criteria in pesticide chambers. The combined effect of Epyrifenacin and terbuthylazine on common grasses and broadleaf weeds was demonstrated by an indoor virulence assay.

Preparation of test agent: the Epyrifenacin raw medicine and the terbuthylazine raw medicine are respectively dissolved by proper amount of acetone, and then are prepared into required concentration for standby by using 0.1 weight percent of Tween 80 aqueous solution; the dosage of the special Ding Jinshan agent is 100, 200, 300 and 400g a.i./ha; the dosage of Epyrifenacin is 1, 5, 10, 15g a.i./ha.

The test method comprises the following steps: the experiment adopts a greenhouse potting method, and seeds of green bristlegrass (Gramineae), crabgrass (Gramineae), amaranthus retroflexus (broadleaf weeds) and purslane (broadleaf weeds) are respectively sown in small flowerpots filled with 4/5 seedling raising matrixes (nutrient soil: vermiculite=3:1), and 5×5 seeds are sown in each pot, and then 1cm of soil is covered. Transferring into artificial climate chamber for culturing at 28deg.C/20deg.C for 14 hr/D with relative humidity of 60%. Adding water into a tray with small flower pot, and adding water by bottom infiltration method. Thinning and fixing after the emergence of weeds, and ensuring that 10 weeds which grow consistently and are not blocked each other exist in each pot. When weeds grow to 2 leaves, carrying out stem and leaf spraying treatment by using an ASS-5 walking type spraying tower, repeating the treatment for 3 times, and setting 0.1% Tween-80 aqueous solution as blank control treatment. After the liquid medicine is completely and naturally air-dried, transferring the weeds to a phytotron for continuous culture, and investigating the fresh weight of the overground parts of each treated weed after 21 days. Except that the water cannot be watered in 1-2 days after spraying the pesticide, the water is watered periodically so as to keep the soil humidity.

The weed control is calculated according to the following formula:

combined action evaluation: reference is made to NY/T1155.7-2006, determination of the combined action of the herbicide part 7 compounding of the laboratory bioassay test guidelines for pesticides. Gowing method for evaluating herbicide combined action mode and calculating formula E ₀ =x+y (100-X)/100; wherein: x is the weed control effect when the dosage of the herbicide A is P; y is weed control effect when the dosage of the herbicide B is Q; e (E) ₀ The herbicide is a theoretical weed control effect when the dosage of A is P and the dosage of B is Q; e is the actual weed control of the herbicide A, B mixed according to the proportion.

Evaluation criteria: when E-E ₀ >10% of the total amount of the herbicide indicates that the herbicide mixture has synergistic effect; when E-E ₀ <-10% indicating antagonism of the herbicide combination; when E-E ₀ The value is + -10%, which indicates that the herbicide mixture produces additive effect.

The combination effect of Epyrifenacin and terbuthylazine compositions on grassy weeds was tested, and the proportions and results are shown in Table 1:

TABLE 1 results of the production of green brifenacil and crab grass by Epyrifenacin and terbuthylazine compositions

The results in Table 1 show that the weeding effect of Epyrifenacin and terbuthylazine on weeds is obviously improved after the Epyrifenacin and terbuthylazine are compounded compared with the single use of the Epyrifenacin and terbuthylazine, and the reagent supply amount shows obvious synergism on the green bristlegrass and Ma Tangjun of Gramineae.

The combination effect of Epyrifenacin and terbuthylazine compositions on amaranthus retroflexus and purslane was tested, and the proportions and results are shown in Table 2.

TABLE 2 results of the biological tests of Epyrifenacin and terbuthylazine compositions on amaranthus retroflexus and Portulaca oleracea

The results in Table 2 show that, after the Epyrifenacin and terbuthylazine are compounded, compared with the single use of the Epyrifenacin and terbuthylazine, the weeding effect on weeds is obviously improved, and the reagent supply amount shows obvious synergistic effect on broadleaf weeds, amaranth retroflexus and purslane.

In conclusion, the combined action of Epyrifenacin and terbuthylazine on 4 weeds after being mixed according to a certain proportion shows a synergistic effect on the weeds in an experimental proportion range.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and not for limiting the same; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the invention.

Claims

1. A herbicide, characterized in that the active ingredients of the herbicide comprise ephifenacin and terbuthylazine;

2. The herbicide according to claim 1, characterized in that the weight ratio of ephifenacin and terbuthylazine is 1:0.1 to 500;

3. The herbicide according to claim 1, characterized in that the active ingredient is present in the herbicide in a weight ratio of 1 to 99%;

4. A herbicide according to claim 3, characterized in that the active ingredient is present in the herbicide in a proportion of 10 to 50% by weight.

5. The herbicide according to any one of claims 1-4, further comprising at least one of an agropharmaceutically acceptable surfactant and a carrier.

6. The herbicide according to any one of claims 1-4, wherein the formulation of the herbicide comprises at least one of emulsifiable concentrates, aqueous emulsions, aqueous suspensions, suspoemulsions, dispersible oil suspensions, wettable powders and water dispersible granules.

7. Use of the herbicide of any one of claims 1-6 for controlling grassy weeds and broadleaf weeds.

8. The use according to claim 7, characterized in that the herbicide is used for controlling grassy weeds and broadleaf weeds in corn fields.

9. The use according to claim 8, wherein the weeds comprise at least one of green bristlegrass, barnyard grass, crab grass, gooseberry, euphorbia lathyris, dayflower, purslane, thistle, quinoa, amaranth, and spiny.

10. The use according to claim 8, wherein the weeds are at least one of green bristlegrass, crabgrass, purslane and amaranthus retroflexus.