CN117481763B - Nasal mucosa puncture positioning device for stem cell transnasal transplantation - Google Patents

Nasal mucosa puncture positioning device for stem cell transnasal transplantation Download PDF

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Publication number
CN117481763B
CN117481763B CN202311776200.1A CN202311776200A CN117481763B CN 117481763 B CN117481763 B CN 117481763B CN 202311776200 A CN202311776200 A CN 202311776200A CN 117481763 B CN117481763 B CN 117481763B
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CN
China
Prior art keywords
block
internal thread
puncture
fixing frame
nasal
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Application number
CN202311776200.1A
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Chinese (zh)
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CN117481763A (en
Inventor
孙君昭
包新杰
刘建国
邱峰
曲志峰
周春辉
董超
李志超
韩晓琛
赵虎林
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First Medical Center of PLA General Hospital
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First Medical Center of PLA General Hospital
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Priority to CN202311776200.1A priority Critical patent/CN117481763B/en
Publication of CN117481763A publication Critical patent/CN117481763A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/24Surgical instruments, devices or methods, e.g. tourniquets for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3468Trocars; Puncturing needles for implanting or removing devices, e.g. prostheses, implants, seeds, wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • A61B2017/3405Needle locating or guiding means using mechanical guide means
    • A61B2017/3409Needle locating or guiding means using mechanical guide means including needle or instrument drives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B2017/348Means for supporting the trocar against the body or retaining the trocar inside the body
    • A61B2017/3482Means for supporting the trocar against the body or retaining the trocar inside the body inside
    • A61B2017/3484Anchoring means, e.g. spreading-out umbrella-like structure
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention provides a nasal mucosa puncture positioning device for stem cell transnasal transplantation, which relates to the field of stem cell transnasal transplantation and comprises the following components: a clamping part for clamping the puncture needle; the clamping part comprises a thread slide block; the guide part comprises an internal thread pipe, and the threads of the internal thread pipe are matched with the thread sliding blocks; the internal thread tube and the thread sliding block rotate relatively, and meanwhile, the thread sliding block moves relatively to the displacement of the internal thread tube; the limiting structure is used for limiting the positioning block of the clamping part not to rotate, but to move along with the displacement of the threaded sliding block, the rotating action is changed into the forward pushing action through a rotating forward pushing and backward pulling mechanism, and the fine adjustment of the puncture needle is realized through the rotation of the threads, so that the problems that the existing puncture instrument is manually operated, the operation is more advanced by depending on the experience of a doctor in clinic, the process needs higher concentration of the doctor, and the doctor can feel heavier fatigue after the puncture is completed are solved.

Description

Nasal mucosa puncture positioning device for stem cell transnasal transplantation
Technical Field
The invention relates to the technical field of stem cell transnasal transplantation, in particular to a nasal mucosa puncture positioning device for stem cell transnasal transplantation.
Background
The stem cells can effectively bypass the blood brain barrier through nasal transplantation, can rapidly enter the central nervous system, have large nasal mucosa area and very rich submucosal blood vessels, and can pass through the blood brain barrier to reach the brain through olfactory nerve, trigeminal nerve and cerebrospinal fluid passage.
In clinic, when stem cells are transplanted through the nose, the stem cells need to be penetrated into nasal mucosa of a patient through a puncture needle, and the tail of the puncture needle is connected with an injection device after the penetration, so that the injection of the stem cells is realized; the existing puncture instrument is manually operated and is influenced by physical conditions of doctors and external environments, the puncture needle is difficult to be pushed into nasal mucosa of a patient stably, the problem that the specified position is not reached or the puncture is excessive easily occurs, more clinical operation is performed by depending on experience of the doctors, the process requires higher concentration of the doctors, and the doctors can feel heavy fatigue after the puncture is completed.
Disclosure of Invention
In view of the above, the present invention provides a nasal mucosa puncture positioning device for nasal transplantation of stem cells, which changes a rotation motion into a forward pushing motion by a rotation forward pushing and backward withdrawing mechanism, and realizes fine adjustment of a puncture needle by rotation of a screw thread.
The invention provides a purpose and an effect of a nasal mucosa puncture positioning device for stem cell transnasal transplantation, which specifically comprise the following steps:
A clamping part for clamping the puncture needle; the clamping part comprises a thread slide block; the guide part comprises an internal thread pipe, and the threads of the internal thread pipe are matched with the thread sliding blocks; the internal thread tube and the thread sliding block rotate relatively, and meanwhile, the thread sliding block moves relatively to the displacement of the internal thread tube; the limiting structure is used for limiting the positioning block of the clamping part not to rotate, but to move along with the displacement of the threaded sliding block.
Preferably, a structure for clamping the puncture needle is arranged on the inner side of the positioning block; the positioning block is arranged in the threaded sliding block; the positioning block is driven by the threaded sliding block to linearly move in the internal threaded pipe, so that the puncture needle linearly moves;
Preferably, the threads of the internally threaded tube are engaged with the threads of the threaded slider.
Preferably, the front end of the inner part of the internal thread pipe is provided with a thread section for guiding the clamping part, and the rear end of the internal thread pipe is a smooth section; when the puncture needle is not close to the puncture position, the clamping part is positioned at the smooth section, and when the puncture needle is close to the puncture position, the clamping part is guided by the thread section;
In some embodiments of the present application, the pitch values of the threads of the internally threaded tube and the threaded slider are adjusted according to the rotational frequency and the push-forward distance.
Preferably, a fixing part is arranged on the outer side of the internal thread pipe, a first end of the fixing part is provided with an opening for extending out of the puncture needle, and a second end of the fixing part is provided with a non-circular opening for extending out of the limiting structure;
the first end of the limiting structure is connected with the positioning block, and no position change occurs; the second end of the limiting structure extends out of the non-circular opening;
In some embodiments of the application, the slide rod defines a structure that is a grip, and the slide rod does not rotate within the non-circular opening;
preferably, the cross section of the slide rod is consistent with the shape of the non-circular opening;
Preferably, the right side of the positioning block is fixedly connected with a sliding rod through a screw;
preferably, the slide rod is a non-circular shape of arbitrary shape, wherein a regular hexagon or square shape is preferred.
Advantageous effects
According to the nasal mucosa puncture positioning device disclosed by the embodiment of the invention, the threaded sliding block is driven to move along the direction of the internally threaded pipe through the rotation of the internally threaded pipe, and meanwhile, the positioning block is driven by the threaded sliding block to displace, so that the puncture needle can complete the puncture action or the needle retraction action, the clamping part is positioned on the smooth section when the puncture needle is not close to the puncture position, the clamping part can be greatly adjusted, and the clamping part is guided by the threaded section when the puncture needle is close to the puncture position, so that the rotary motion is converted into the linear motion, and the fine adjustment when the puncture needle is close to the puncture position is realized;
As described above, when the internal thread pipe rotates, the forward pushing distance of the thread slider is increased in the same ratio, and meanwhile, the puncture precision of the puncture needle is reduced, and similarly, the forward pushing distance of the thread slider is reduced in the same ratio, and the puncture precision of the puncture needle is increased;
By using the device, when the puncture needle is about to approach the puncture position, the puncture needle is limited by the screw thread, and the rotary motion realized by the screw thread is converted into linear motion, so that the accuracy of the displacement of the puncture needle is improved when the puncture needle approaches the puncture position, a doctor does not need to pay excessive attention to control, the operation is simpler and more convenient, and the operation experience is not needed too much, so that the success rate of the puncture of the doctor can be effectively reduced.
In addition, in another embodiment, the fixing part adopts the holding part, so that the manual operation of the puncturing action is realized by the electric drive, meanwhile, the intelligent control of the puncturing depth can be synchronously realized by the electric drive, the puncturing efficiency can be greatly improved, and the fatigue of doctors can be delayed.
Drawings
In order to more clearly illustrate the technical solution of the embodiments of the present invention, the drawings of the embodiments will be briefly described below.
The drawings described below are only for illustration of some embodiments of the invention and are not intended to limit the invention.
In the drawings:
Fig. 1 is a schematic perspective view of the whole nasal mucosa puncture positioning device in the present invention.
Fig. 2 is an exploded view of the entirety of the nasal mucosa puncture positioning apparatus of the present invention.
Fig. 3 is a schematic perspective cross-sectional view of the puncture needle and the clamping portion of the nasal mucosa puncture positioning apparatus of the present invention.
Fig. 4 is a schematic perspective cross-sectional view of a guide portion of a nasal mucosa puncture positioning apparatus according to the present invention.
Fig. 5 is an enlarged partial schematic view of the nasal mucosa puncture positioning apparatus of the present invention at a shown in fig. 4.
Fig. 6 is a schematic perspective cross-sectional view of a fixed portion of a nasal mucosa puncture positioning apparatus according to the present invention.
Fig. 7 is a schematic perspective view of a measurement portion in a third embodiment of a nasal mucosa puncture positioning apparatus according to the present invention.
Fig. 8 is an enlarged partial schematic view of the nasal mucosa puncture positioning apparatus of the present invention at B shown in fig. 7.
Fig. 9 is a schematic perspective view of a sliding portion in a second embodiment of a nasal mucosa puncture positioning apparatus according to the present invention.
Fig. 10 is an enlarged partial schematic view of the nasal mucosa puncture positioning apparatus of the present invention at C shown in fig. 9.
Fig. 11 is a schematic perspective view of a nasal mucosa puncture positioning apparatus according to a second embodiment of the present invention.
List of reference numerals
1. A puncture needle; 101. a tip; 102. tail end;
2. A clamping part; 201. a positioning block; 202. a driving member A; 203. a pushing block; 204. a thread slider; 205. an elastic support; 206. a slide rod;
3.A guide part; 301. an internally threaded tube; 302. rotating the handle;
4. A mounting part; 401. a fixing frame A; 402. a bearing; 403. a rubber nozzle; 404. a rubber handle;
5. A measuring section; 501. a mounting frame; 502. a pointer; 503. a lens; 504. measuring a rod;
6. A sliding part; 601. rotating the slide block; 602. a limit column;
7. a fixing frame B;
8. A grip portion; 801. a holding frame; 802. a control switch; 803. a driving member B; 804. and a synchronizer.
Detailed Description
In order to make the objects, aspects and advantages of the technical solution of the present invention more clear, the technical solution of the embodiment of the present invention will be clearly and completely described below with reference to the accompanying drawings of the specific embodiment of the present invention.
Examples: please refer to fig. 1 to 11:
embodiment one:
As shown in fig. 1 and 2, the present invention provides a nasal mucosa puncture positioning device for nasal transplantation of stem cells, comprising: a clamping part 2 for clamping the puncture needle 1; the clamping part 2 comprises a threaded slider 204; a guide part 3 comprising an internally threaded tube 301, the threads of the internally threaded tube 301 being adapted to the thread blocks 204; while the internal thread tube 301 and the thread slider 204 relatively rotate, the thread slider 204 moves in a displacement manner relative to the internal thread tube 301; the positioning block 201 for defining the clamping portion 2 does not rotate but moves in a displacement manner following the thread slider 204.
As shown in fig. 3, a structure for holding the puncture needle 1 is provided inside the positioning block 201; the positioning block 201 is arranged inside the thread slider 204; the positioning block 201 is driven by the thread slider 204 to linearly move inside the internal thread tube 301, so that the puncture needle 1 linearly moves.
In a more specific embodiment, the threads of the internally threaded tube 301 intermesh with the threads of the thread blocks 204; through the rotation of the internal thread tube 301, the thread slider 204 is driven to move along the direction of the internal thread tube 301, and meanwhile, the positioning block 201 is also driven by the thread slider 204 to generate displacement, so that the puncture needle 1 can complete the puncture action or the retraction action.
As shown in fig. 4 and 5, the front end of the inner part of the inner threaded pipe 301 is provided with a threaded section for guiding the clamping part 2, and the rear end of the inner threaded pipe 301 is a smooth section; when the puncture needle 1 is not close to the puncture position, the clamping part 2 is positioned at the smooth section, the large-scale adjustment can be performed, when the puncture needle 1 is close to the puncture position, the clamping part 2 is guided by the thread section, the rotary motion is converted into the linear motion, and the fine adjustment when the puncture needle 1 is close to the puncture position is realized;
Or adjusting the screw pitch value of the threads of the internally threaded pipe 301 and the thread slider 204 according to the requirements of the rotation frequency and the forward pushing distance; if the pitch increases, the push-forward distance of the thread slider 204 increases in the same ratio when the internally threaded tube 301 rotates, and the puncture accuracy of the puncture needle 1 decreases, and similarly, the pitch decreases, the push-forward distance of the thread slider 204 decreases in the same ratio, and the puncture accuracy of the puncture needle 1 increases.
As shown in fig. 4 and 5, a fixing part is arranged on the outer side of the internal thread tube 301, a first end of the fixing part is provided with an opening for the puncture needle 1 to extend, and a second end of the fixing part is provided with a non-circular opening for the limiting structure to extend;
The first end of the limiting structure is connected with the positioning block 201, and no position change occurs; the positioning block 201 does not change in position, so that the tip 101 of the puncture needle 1 clamped by the positioning block 201 does not change in position when the puncture needle 1 performs a puncture operation, and the stability of the puncture needle 1 during needle insertion is ensured; the second end of the limiting structure extends out of the non-circular opening;
Specifically, the limiting structure is a sliding rod 206, and the sliding rod 206 does not rotate in the non-circular opening;
In more particular embodiments, the cross section of the slide rod 206 conforms to the shape of the non-circular opening; the sliding rod 206 is used for limiting the position of the positioning block 201, and is matched with a non-circular opening to guide and stabilize the positioning block 201, so that vibration cannot occur due to the matching of threads in the process of relatively rotating the internal thread tube 301 and the thread slider 204, and the stability of the puncture needle 1 during puncture is further ensured;
in a more specific embodiment, the right side of the positioning block 201 is fixedly connected with a sliding rod 206 through a screw;
In more specific embodiments, the slide bar 206 is a non-circular shape of any shape, with regular hexagons or squares being preferred.
As shown in fig. 4, a rotary handle 302 is fixedly connected to the outer side of the internally threaded tube 301, and is used for controlling the internally threaded tube 301 to rotate; by arranging the rotary handle 302, the internal thread tube 301 has a certain protruding part relative to the fixed part, when a medical staff holds the fixing frame A401 by one hand, the other hand can conveniently rotate the internal thread tube 301 by the rotary handle 302, so that the operation is more convenient and comfortable;
In a more specific embodiment, the rotary handle 302 controls the rotation of the internally threaded tube 301, and a fixing part, specifically an installation part 4, is arranged on the outer side of the internally threaded tube 301; the mounting part 4 comprises a fixing frame A401, wherein a first end of the fixing frame A401 is provided with an opening for the tip 101 of the puncture needle 1 to extend out, and a second end of the fixing frame A401 is provided with a non-circular opening for the limiting structure to extend out;
In a more specific embodiment, mounting grooves are respectively formed in the left side and the right side of the fixing frame A401; a bearing 402 is fixedly connected in the mounting groove of the fixing frame A401; two bearings 402 are respectively sleeved on the left side and the right side of the internal thread pipe 301 and are used for rotating the internal thread pipe 301; the end of the slide rod 206 is inserted inside the non-circular opening of the fixing frame a 401; the sliding rod 206 is matched with an opening with a shape corresponding to the fixing frame A401 to limit the rotation freedom degree of the clamping part 2, so that the clamping part 2 can only move linearly under the drive of the internal thread pipe 301;
In a more specific embodiment, an enlarged rubber handle 404 setting part is arranged on the fixing frame A401;
in a more specific embodiment, the rubber handle 404 is larger than the other positions of the fixing frame a401, and the fixing frame a401 can form two parts by the arrangement, so that the blocking of hands during operation is ensured;
In a more specific embodiment, the fixing frame a401 is provided with a notch corresponding to the rotating handle 302, so as to facilitate the operation of the rotating handle 302 by the hand.
As shown in fig. 9 and 10, the device also comprises a fixing frame B7;
Or the fixing part is a fixing frame B7; the fixing frame B7 is fixedly connected with the internal thread tube 301; the right side of the fixed frame B7 is provided with a through hole with the same cross section shape as the limit post 602 of the sliding part 6; by replacing the fixing frame B7, the other driving mode of the automatic positioning device for transnasal puncture is realized;
Or the screw slider 204 is replaced with a rotating slider 601 of the sliding portion 6; the rotary slide block 601 is rotatably connected to the outer side of the positioning block 201, and the right side of the rotary slide block 601 is connected with a handle through a tubular structure; threads are formed on the outer side of the rotary slide block 601, and the threads of the rotary slide block 601 are meshed with the threads of the internal thread pipe 301; when the rotary slide block 601 is manually rotated, the rotary slide block 601 can linearly move along the inner part of the internally threaded pipe 301 through the engagement of the threads;
Or the slide rod 206 is replaced with a limit post 602 of the sliding part 6; the limiting post 602 is of any shape with a non-circular end, and the limiting post 602 passes through the tubular structure of the rotating slider 601; the tail end of the limit post 602 is inserted into the through hole of the fixing frame B7; the positioning block 201 is used for limiting the positioning block 201 when the rotating slide block 601 rotates, so that the positioning block 201 is prevented from carrying the puncture needle 1 to rotate along with the rotating slide block 601.
The specific use mode of the embodiment is as follows: after the puncture needle 1 is mounted at the front end of the clamping part 2, the puncture needle 1 is retracted into the inner threaded tube 301, pollution or scratch to other people in the holding process is avoided, one hand of medical staff holds the fixing part through the rubber handle 404, the needle outlet of the fixing part is aligned to the position of the nasal cavity of a patient, which needs to be punctured, firstly, the rotating handle 302 is rotated through the other hand, the inner threaded tube 301 rotates, then the clamping part 2 linearly moves in the inner threaded tube 301 through the fit between threads, secondly, the threads of the rotating slider 601 are matched with the threads of the inner threaded tube 301 through the rotation of the rotating slider 601, meanwhile, the structures of the puncture needle 1 and the clamping puncture needle 1 are kept not to rotate under the limit of the limit column 602, and then the puncture needle 1 generates puncture action.
Embodiment two:
In addition to the first embodiment, as shown in fig. 11, the grip portion 8 includes: a grip 801, a control switch 802, a driving member B803, and a synchronizer 804;
Or the fixing part is a holding part 8 for driving the guide part 3 to rotate by using an electric driving mode; the holding rack 801 is gun-shaped, and a bearing 402 is inserted into a mounting groove of the holding rack 801; for rotation of the internally threaded tube 301 within the grip portion 8, the gun-like structure is more convenient to grip.
In more specific embodiments, the control switch 802 is disposed inside the holding rack 801 and is used for electrically connecting and controlling the electrical components of the whole holding part 8; compared with manual operation, the electric drive can be used for more stably pushing the puncture needle 1, and simultaneously, the electric drive can be used for intelligently controlling the puncture depth, so that the operation is more convenient and faster for medical staff, and the puncture efficiency can be effectively improved;
in a more specific embodiment, a driving member B803 is mounted on the right side of the grip rack 801, and the driving member B803 is a stepper motor for driving the rotation of the internally threaded tube 301;
In a more specific embodiment, the synchronizer 804 is composed of an upper synchronizing wheel, a lower synchronizing wheel and a synchronous belt connecting the two synchronizing wheels; the synchronizing wheel of the upper synchronizer 804 is fixedly connected to the outer side of the inner threaded pipe 301, and the synchronizing wheel of the lower synchronizer 804 is fixedly connected to the outer side of the main shaft of the driving piece B803; and is used for transmitting the power of the driving piece B803 to the internally threaded tube 301 to drive the internally threaded tube 301 to rotate.
As shown in fig. 7 and 8, the other end of the fixing portion is provided with a measuring portion 5, specifically, a mounting frame 501 of the measuring portion 5 is fixedly connected to the right side of a fixing frame a401 by a screw;
in a more specific embodiment, a pointer 502 is fixedly connected to the right side of the mounting frame 501, and a lens 503 is arranged at the upper end of the mounting frame 501;
or the slide rod 206 is replaced with a measuring rod 504; the scale is offered on the outside of measuring rod 504, and in the in-process that clamping part 2 drove pjncture needle 1 impel, can clear measurement to pjncture needle 1's puncture distance through lens 503 cooperation pointer 502, makes pjncture needle 1's control more accurate.
As shown in fig. 6, a rubber nozzle 403 is fixedly connected to the first end of the fixing portion, and is inserted into the nasal cavity to guide the puncture needle 1 and protect the non-puncture site.
The specific use mode of the embodiment is as follows: after the puncture needle 1 is mounted at the front end of the clamping part 2, the puncture needle 1 is retracted into the internal thread tube 301, and the manual rotation mode in the first embodiment is replaced by the cooperation of the driving part B803 and the synchronizer 804, so that medical staff can drive the internal thread tube 301 to rotate by pressing the control switch 802, and the puncture needle 1 is pushed in by the cooperation of threads.
Embodiment III:
As shown in fig. 3, the clamping part 2 further includes a driving member a202, a push block 203 and an elastic support 205;
in a more specific embodiment, a driving piece A202 is fixedly arranged on the right side inside the positioning block 201; a through hole is formed in the center of the left end of the positioning block 201;
In a more specific embodiment, the driving member a202 is composed of a motor and a spool connected to the main shaft of the motor, and the spool pulls the push block 203; when the spool of the driving member a202 receives the traction wire, the push block 203 is driven to move to the right;
In a more specific embodiment, the left side of the push block 203 is in a truncated cone-shaped structure, and the push block 203 is disposed on the left side of the positioning block 201; the push block 203 is connected with the positioning block 201 in a sliding manner along the direction of the through hole in the center of the left end of the positioning block 201; the inclined surface at the lower end of the elastic support 205 is extruded by the round table of the push block 203;
In a more specific embodiment, the elastic support 205 is of a Y-shaped elastic metal structure, the upper side of the right end of the elastic support 205 is slidably connected with the positioning block 201, and the lower end of the right side of the elastic support 205 is fixedly connected with the positioning block 201;
In a more specific embodiment, the inner ends of the six elastic brackets 205 are uniformly and tightly attached to the outer surface of the round table of the push block 203; after being extruded by the push block 203, the six elastic brackets 205 deform outwards under the action of self elasticity, so as to support the tail end 102 of the puncture needle 1; the tail end 102 is supported by the elastic support 205, the puncture needle 1 is further held, after puncture, the driving piece A202 releases the push block 203, the push block 203 can be reset under the elastic action of the elastic support 205, the elastic support 205 is deformed in a recovery mode, the puncture needle 1 is further loosened, and when the puncture needle 1 is held, the operation of clamping is greatly simplified, and time spent for clamping and loosening the puncture needle 1 before and after puncture is reduced.
The specific use mode of the embodiment is as follows: when the spool of the driving piece A202 stores the traction wire, the pushing block 203 is driven to move to the right side, meanwhile, the inclined surface at the lower end of the elastic support 205 is extruded by the round table of the pushing block 203, the elastic support 205 is utilized to support the inside of the tail end 102, then the puncture needle 1 is held, after puncture, the pushing block 203 is released by the driving piece A202, the pushing block 203 is reset under the elastic action of the elastic support 205, and meanwhile, the elastic support 205 is deformed in a recovery mode, and then the puncture needle 1 is loosened.
The above is only an exemplary embodiment of the present invention and is not intended to limit the scope of the present invention, which is defined by the appended claims.

Claims (9)

1. A nasal mucosa puncture positioning device for nasal transplantation of stem cells, comprising:
a clamping part (2) for clamping the puncture needle (1); the clamping part (2) comprises a thread slider (204);
a guide part (3) comprising an internally threaded tube (301), the threads of the internally threaded tube (301) being adapted to the thread slider (204); the internal thread tube (301) and the thread sliding block (204) rotate relatively, and the thread sliding block (204) moves relatively to the displacement of the internal thread tube (301);
The limiting structure is used for limiting the positioning block (201) of the clamping part (2) not to rotate but to move along with the thread slide block (204) in a displacement manner;
The inner side of the positioning block (201) is provided with a structure for clamping the puncture needle (1); the positioning block (201) is arranged in the threaded sliding block (204); the positioning block (201) is driven by the thread sliding block (204) to linearly move in the internal thread pipe (301), so that the puncture needle (1) linearly moves;
the front end of the inner part of the inner threaded pipe (301) is provided with a threaded section for guiding the clamping part (2), and the rear end of the inner threaded pipe (301) is a smooth section; when the puncture needle (1) is not close to the puncture position, the clamping part (2) is positioned on the smooth section, and when the puncture needle (1) is close to the puncture position, the clamping part (2) is guided by the thread section;
the clamping part (2) further comprises a driving piece A (202), a pushing block (203) and an elastic bracket (205); the driving piece A (202) consists of a motor and a spool connected with a main shaft of the motor, and the spool pulls the push block (203); the pushing block (203) is connected with the positioning block (201) in a sliding manner along the direction of the through hole in the center of the left end of the positioning block (201);
A driving piece A (202) is fixedly arranged on the right side inside the positioning block (201); a through hole is formed in the center of the left end of the positioning block (201); the pushing block (203) is arranged on the left side of the positioning block (201); the elastic support (205) is of a Y-shaped elastic metal structure, the upper side of the right end of the elastic support (205) is in sliding connection with the positioning block (201), and the lower end of the right side of the elastic support (205) is fixedly connected with the positioning block (201); the left side of the push block (203) is in a truncated cone-shaped structure, and the inner ends of the six elastic supports (205) are uniformly and tightly attached to the outer surface of the truncated cone of the push block (203); the inclined surface at the lower end of the elastic support (205) can be extruded by the round table of the push block (203); six elastic supports (205) are extruded by the push blocks (203) and then deform outwards under the action of self elasticity, so as to support the tail end (102) of the puncture needle (1).
2. The nasal mucosa puncturing and positioning device for nasal transplantation of stem cells as set forth in claim 1, wherein the threads of said internally threaded tube (301) are engaged with the threads of the threaded slider (204).
3. The nasal mucosa puncturing and positioning device for nasal transplantation of stem cells according to claim 1, wherein the screw pitch values of the threads of the internally threaded tube (301) and the thread slider (204) are adjusted according to the rotation frequency and the forward pushing distance.
4. The nasal mucosa puncturing and positioning device for nasal transplantation of stem cells according to claim 1, wherein a fixing part is arranged on the outer side of the internal thread tube (301), a first end of the fixing part is provided with an opening for the puncturing needle (1) to extend out, and a second end of the fixing part is provided with a non-circular opening for the limiting structure to extend out;
the first end of the limiting structure is connected with the positioning block (201) and does not change in position; the second end of the limiting structure extends out of the non-circular opening;
A slide rod (206) connected with the clamping part (2) is limited, and the slide rod (206) cannot rotate in the non-circular opening;
The cross section of the sliding rod (206) is consistent with the shape of the non-circular opening;
The right side of the positioning block (201) is fixedly connected with a sliding rod (206) through a screw;
The slide rod (206) is a non-circular shape of arbitrary shape.
5. The nasal mucosa puncturing and positioning device for nasal transplantation of stem cells according to claim 4, wherein a rotary handle (302) is fixedly connected to the outer side of the internal thread tube (301) for controlling the internal thread tube (301) to rotate;
The rotary handle (302) controls the internal thread tube (301) to rotate, and a fixing part, in particular a mounting part (4), is arranged on the outer side of the internal thread tube (301); the mounting part (4) comprises a fixing frame A (401), wherein a first end of the fixing frame A (401) is provided with an opening for the tip (101) of the puncture needle (1) to extend out, and a second end of the fixing frame A is provided with a non-circular opening for the limiting structure to extend out;
mounting grooves are respectively formed in the left side and the right side of the fixing frame A (401); a bearing (402) is fixedly connected in the mounting groove of the fixing frame A (401); the two bearings (402) are respectively sleeved on the left side and the right side of the internal thread pipe (301) and used for rotating the internal thread pipe (301); the tail end of the sliding rod (206) is inserted into the non-circular opening of the fixing frame A (401);
an enlarged rubber handle (404) setting part is arranged on the fixing frame A (401);
The rubber handle (404) is arranged in a larger size than other positions of the fixing frame A (401), and the fixing frame A (401) can form two parts by the arrangement, so that the blocking of hands during operation is ensured;
the fixing frame A (401) is provided with a notch corresponding to the rotary handle (302), so that the operation of the rotary handle (302) by a hand is facilitated.
6. The nasal mucosa penetration positioning apparatus for nasal transplantation of stem cells as recited in claim 4, further comprising: a fixing frame B (7);
The fixing part is a fixing frame B (7); the fixing frame B (7) is fixedly connected with the internal thread pipe (301); the right side of the fixing frame B (7) is provided with a through hole with the same cross section shape as a limit post (602) of the sliding part (6);
The thread slider (204) is replaced by a rotating slider (601) of the sliding part (6); the rotary slide block (601) is rotatably connected to the outer side of the positioning block (201), and the right side of the rotary slide block (601) is connected with a handle through a tubular structure; the outer side of the rotary sliding block (601) is provided with threads, and the threads of the rotary sliding block (601) are meshed with the threads of the internal thread pipe (301);
The sliding rod (206) is replaced by a limit column (602) of the sliding part (6); the limiting column (602) is of any shape with a non-circular tail end, and the limiting column (602) penetrates through the tubular structure of the rotary slide block (601); the tail end of the limiting column (602) is inserted into the through hole of the fixing frame B (7).
7. The nasal mucosa penetration positioning apparatus for nasal transplantation of stem cells as recited in claim 4, further comprising: a grip (8);
The grip part (8) comprises: a holding frame (801), a control switch (802), a driving piece B (803) and a synchronizer (804);
The fixing part is a holding part (8), the holding rack (801) is gun-shaped, and a bearing (402) is inserted into a mounting groove of the holding rack (801); for rotation of the internally threaded tube (301) within the grip (8);
a control switch (802) is arranged in the holding rack (801) and is used for electrically connecting the whole electric element of the holding part (8) and controlling the electric element;
A driving piece B (803) is arranged on the right side of the holding frame (801), and the driving piece B (803) is a stepping motor;
the synchronizer (804) consists of an upper synchronizing wheel, a lower synchronizing wheel and a synchronous belt connected with the two synchronizing wheels; the synchronizing wheel of the synchronizer (804) at the upper part is fixedly connected with the outer side of the internal thread pipe (301), and the synchronizing wheel of the synchronizer (804) at the lower part is fixedly connected with the outer side of the main shaft of the driving piece B (803).
8. The positioning device for nasal mucosa penetration of stem cells through nasal transplantation according to claim 5, wherein the other end of the fixing part is provided with a measuring part (5), in particular a mounting frame (501) of the measuring part (5) is fixedly connected to the right side of a fixing frame A (401) through screws;
The right side of the mounting frame (501) is fixedly connected with a pointer (502), and the upper end of the mounting frame (501) is provided with a lens (503);
-the slide rod (206) is replaced with a measuring rod (504); the outer side of the measuring rod (504) is provided with scales.
9. The positioning device for nasal mucosa penetration of stem cells through nasal transplantation according to claim 4, wherein the first end of the fixing part is fixedly connected with a rubber nozzle (403) for being inserted into the nasal cavity to guide the puncture needle (1) and protect the non-puncture part.
CN202311776200.1A 2023-12-22 2023-12-22 Nasal mucosa puncture positioning device for stem cell transnasal transplantation Active CN117481763B (en)

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