CN117473276A - Small molecular detection data analysis system - Google Patents

Small molecular detection data analysis system Download PDF

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CN117473276A
CN117473276A CN202311818564.1A CN202311818564A CN117473276A CN 117473276 A CN117473276 A CN 117473276A CN 202311818564 A CN202311818564 A CN 202311818564A CN 117473276 A CN117473276 A CN 117473276A
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data
report
user interface
analysis
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王占宝
康维为
陈杭飞
王文雅
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Beijing Jintai Kangchen Biotechnology Co ltd
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Beijing Jintai Kangchen Biotechnology Co ltd
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    • G06FELECTRIC DIGITAL DATA PROCESSING
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • GPHYSICS
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    • G06COMPUTING; CALCULATING OR COUNTING
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    • G06F9/00Arrangements for program control, e.g. control units
    • G06F9/06Arrangements for program control, e.g. control units using stored programs, i.e. using an internal store of processing equipment to receive or retain programs
    • G06F9/44Arrangements for executing specific programs
    • G06F9/451Execution arrangements for user interfaces
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F2221/00Indexing scheme relating to security arrangements for protecting computers, components thereof, programs or data against unauthorised activity
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    • G06F2221/2141Access rights, e.g. capability lists, access control lists, access tables, access matrices

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Abstract

The invention discloses a small molecular detection data analysis system, which comprises a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report export module, a standardization module, an updating module and a security module; the system comprises a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report deriving module, a standardization module, an updating module and a security module, wherein the sensor module, the data acquisition preprocessing module, the data processing analysis module, the user interface module, the report deriving module, the standardization module and the updating module are in communication connection; the system can realize the high-efficiency processing of the small molecular detection data by the combination of the data acquisition preprocessing module and the data processing analysis module, monitor and analyze the small molecular detection data in real time, and a user can easily interact with the system, including inputting instructions, checking results and carrying out necessary operations to generate a standardized report, thereby facilitating the user to share and archive the detection results and being greatly helpful for research papers, quality inspection reports or supervision compliance.

Description

Small molecular detection data analysis system
Technical Field
The invention relates to the technical field of small molecule detection, in particular to a small molecule detection data analysis system.
Background
Small molecule detection generally refers to detection and analysis of compounds with smaller molecular structures, such as organic molecules, drugs, natural products, etc., and has a relatively small molecular weight, and has been widely used in the fields of chemistry, biology, medicine, etc.
In general, a conventional small molecule detection system adopts a single architecture, functions of all parts are integrated together instead of being divided into modules, the architecture limits flexibility and expansibility of the system, targeted modification and upgrading of the system are not facilitated, a fixed functional architecture is difficult to update or replace easily, when new technology or improvement needs to be introduced, large-scale modification needs to be performed on the whole system, time and cost are increased, and a centralized system can be more easily an attack target because of high coupling degree of all parts of the system, and once a part of the system has loopholes, the security of the whole system can be threatened.
In summary, a small molecular detection data analysis system is required to solve the above problems.
Disclosure of Invention
The present invention is directed to a small molecular detection data analysis system, which solves the above-mentioned problems of the related art.
In order to achieve the above purpose, the present invention provides the following technical solutions:
the small molecular detection data analysis system comprises a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report deriving module, a standardization module, an updating module and a security module;
the system comprises a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report deriving module, a standardization module, an updating module and a security module, wherein the sensor module, the data acquisition preprocessing module, the data processing analysis module, the user interface module, the report deriving module, the standardization module and the updating module are in communication connection;
the sensor module is connected with the data acquisition preprocessing module in a unidirectional way, and transmits the original data to the data acquisition preprocessing module in a unidirectional way for subsequent processing;
the data acquisition preprocessing module is connected with the data processing analysis module in a unidirectional way, and transmits the processed data to the data processing analysis module in a unidirectional way for further analysis;
the data processing analysis module is connected with the user interface module in a bidirectional way, and transmits an analysis result to the user interface module and receives input and control commands of the user interface module;
the user interface module is connected with the report export module in a unidirectional way, the user interface module transmits an export request to the report export module in a unidirectional way, and the report export module sends a generated report to the user interface module;
the data processing analysis module is connected with the report deriving module in a one-way, and sends an analysis result to the report deriving module to trigger report generation;
the user interface module is in bidirectional connection with the data export module, exchanges information with the data export module through the bidirectional connection, sends export requests, and transmits exported data;
the standardized module is connected with the data processing and analyzing module in a one-way, and sends standardized information to the data processing and analyzing module so as to ensure the compatibility of the system and industry standards;
the user interface module sends an update request to the update module through the bidirectional connection, and the update module sends update information to the user interface module through the bidirectional connection;
the security module is in communication connection with other modules, and the security module establishes unidirectional or bidirectional connection with other modules so as to ensure confidentiality and integrity of data transmission.
As a preferred embodiment of the present invention, the sensor module includes an optical sensor and an electrochemical sensor for measuring physical or chemical properties in a sample to generate raw data.
As a preferable technical scheme of the invention, the data acquisition and preprocessing module comprises a data acquisition unit and a preprocessing unit;
the data acquisition and preprocessing module acquires the original data output by the sensor into the system through the data acquisition unit, so that high-speed and accurate data acquisition is realized, and high-quality input is ensured.
The data acquisition and preprocessing module performs signal amplification, filtering and correction processing on the original data through the preprocessing unit, ensures the quality of the acquired data, and prepares the data for subsequent analysis.
As a preferable technical scheme of the invention, the data processing and analyzing module comprises a data processing software unit and a data analyzing algorithm unit;
the data processing analysis module processes data through the data processing software unit, performs denoising, correction and alignment operation, provides deep processing on the data, and optimizes data quality;
the data processing and analyzing module utilizes an algorithm to interpret and analyze data through a data analyzing algorithm unit, extracts information about small molecules, and can accurately identify and quantify target molecules.
As a preferred embodiment of the present invention, the user interface module includes a GUI element;
the user interface module provides a user-friendly interface through the GUI unit, displays real-time data, controls experiments and visualizes results, is visual and easy to use, and is convenient for users to operate and monitor.
As a preferable technical scheme of the invention, the report and export module comprises a report generating unit and a data export unit;
the report and export module automatically generates an experiment result report through a report generating unit, wherein the report and export module comprises analysis parameters, charts and conclusions, and generates clear and detailed experiment results, so that the user can understand the experiment results conveniently.
The reporting and exporting module allows a user to export data to other analysis tools through the data exporting unit, supports further research and sharing, provides flexible data exporting options, and accords with industry standards.
As a preferable technical scheme of the invention, the standardized module is used for implementing industry standards, ensuring interoperability of the system with other devices and software, and adopting internationally approved data exchange standards and communication protocols, and ensuring seamless integration of the system.
As a preferable technical scheme of the invention, the updating module is used for providing a periodic updating mechanism of system firmware and software, adapting to new technology and algorithm, implementing remote firmware/software updating function and ensuring continuous updating of the system.
As a preferable technical scheme of the invention, the security module is used for implementing data encryption, identity verification and access control, ensuring confidentiality and integrity of data, and ensuring data security and user privacy by using an encryption algorithm, multi-level identity verification and authority control.
Compared with the prior art, the invention has the beneficial effects that: each functional module of the system is a relatively independent unit, independent development, testing and maintenance are realized, the work of each module can be coordinated, smooth transmission and processing of data are realized, confidentiality and integrity of the data in the system are ensured, the system can effectively prevent unauthorized access and data leakage through means such as encryption, identity verification and access control, meanwhile, the combination of the data acquisition preprocessing module and the data processing analysis module can realize efficient processing of small molecular detection data, the small molecular detection data can be monitored and analyzed in real time, a user can easily interact with the system, the input instruction and the check result are included, necessary operation is carried out, a standardized report is generated, the user can conveniently share and archive the detection result, and great help is provided for researching papers, quality inspection reports or supervision compliance.
Drawings
FIG. 1 is a diagram of a small molecular assay data analysis system according to the present invention;
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1, the present invention provides a technical solution:
the small molecular detection data analysis system comprises a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report deriving module, a standardization module, an updating module and a security module;
the system comprises a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report deriving module, a standardization module, an updating module and a security module, wherein the sensor module, the data acquisition preprocessing module, the data processing analysis module, the user interface module, the report deriving module, the standardization module and the updating module are in communication connection;
the sensor module is connected with the data acquisition preprocessing module in a unidirectional way, and transmits the original data to the data acquisition preprocessing module in a unidirectional way for subsequent processing;
the data acquisition preprocessing module is connected with the data processing analysis module in a unidirectional way, and transmits the processed data to the data processing analysis module in a unidirectional way for further analysis;
the data processing analysis module is connected with the user interface module in a bidirectional way, and transmits an analysis result to the user interface module and receives input and control commands of the user interface module;
the user interface module is connected with the report export module in a unidirectional way, the user interface module transmits an export request to the report export module in a unidirectional way, and the report export module sends a generated report to the user interface module;
the data processing analysis module is connected with the report deriving module in a one-way, and sends an analysis result to the report deriving module to trigger report generation;
the user interface module is in bidirectional connection with the data export module, exchanges information with the data export module through the bidirectional connection, sends export requests, and transmits exported data;
the standardized module is connected with the data processing and analyzing module in a one-way, and sends standardized information to the data processing and analyzing module so as to ensure the compatibility of the system and industry standards;
the user interface module sends an update request to the update module through the bidirectional connection, and the update module sends update information to the user interface module through the bidirectional connection;
the security module is in communication connection with other modules, and the security module establishes unidirectional or bidirectional connection with other modules so as to ensure confidentiality and integrity of data transmission.
Still further, the sensor module includes an optical sensor and an electrochemical sensor for measuring a physical or chemical property in a sample, generating raw data.
Further, the data acquisition and preprocessing module comprises a data acquisition unit and a preprocessing unit;
the data acquisition and preprocessing module acquires the original data output by the sensor into the system through the data acquisition unit, so that high-speed and accurate data acquisition is realized, and high-quality input is ensured.
The data acquisition and preprocessing module performs signal amplification, filtering and correction processing on the original data through the preprocessing unit, ensures the quality of the acquired data, and prepares the data for subsequent analysis.
Further, the data processing analysis module comprises a data processing software unit and a data analysis algorithm unit;
the data processing analysis module processes data through the data processing software unit, performs denoising, correction and alignment operation, provides deep processing on the data, and optimizes data quality;
the data processing and analyzing module utilizes an algorithm to interpret and analyze data through a data analyzing algorithm unit, extracts information about small molecules, and can accurately identify and quantify target molecules.
Still further, the user interface module includes a GUI element;
the user interface module provides a user-friendly interface through the GUI unit, displays real-time data, controls experiments and visualizes results, is visual and easy to use, and is convenient for users to operate and monitor.
Further, the report and export module comprises a report generating unit and a data export unit;
the report and export module automatically generates an experiment result report through a report generating unit, wherein the report and export module comprises analysis parameters, charts and conclusions, and generates clear and detailed experiment results, so that the user can understand the experiment results conveniently.
The reporting and exporting module allows a user to export data to other analysis tools through the data exporting unit, supports further research and sharing, provides flexible data exporting options, and accords with industry standards.
Furthermore, the standardized module is used for implementing industry standards, ensuring interoperability of the system with other devices and software, and ensuring seamless integration of the system by adopting internationally approved data exchange standards and communication protocols.
Furthermore, the updating module is used for providing a regular updating mechanism of system firmware and software, adapting to new technology and algorithm, implementing remote firmware/software updating function and ensuring continuous updating of the system.
Furthermore, the security module is used for implementing data encryption, authentication and access control, ensuring confidentiality and integrity of data, and ensuring data security and user privacy by using an encryption algorithm, multi-level authentication and authority control.
Examples
The small molecular detection data analysis system is composed of a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report deriving module, a standardization module, an updating module and a security module, wherein:
the system comprises a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report deriving module, a standardization module, an updating module and a security module, wherein the sensor module, the data acquisition preprocessing module, the data processing analysis module, the user interface module, the report deriving module, the standardization module and the updating module are in communication connection; the sensor module is connected with the data acquisition preprocessing module in a unidirectional way, and transmits the original data to the data acquisition preprocessing module in a unidirectional way for subsequent processing; the data acquisition preprocessing module is connected with the data processing analysis module in a unidirectional way, and transmits the processed data to the data processing analysis module in a unidirectional way for further analysis; the data processing analysis module is connected with the user interface module in a bidirectional way, and transmits an analysis result to the user interface module and receives input and control commands of the user interface module; the user interface module is connected with the report export module in a unidirectional way, the user interface module transmits an export request to the report export module in a unidirectional way, and the report export module sends a generated report to the user interface module; the data processing analysis module is connected with the report deriving module in a one-way, and sends an analysis result to the report deriving module to trigger report generation; the user interface module is in bidirectional connection with the data export module, exchanges information with the data export module through the bidirectional connection, sends export requests, and transmits exported data; the standardized module is connected with the data processing and analyzing module in a one-way, and sends standardized information to the data processing and analyzing module so as to ensure the compatibility of the system and industry standards; the user interface module sends an update request to the update module through the bidirectional connection, and the update module sends update information to the user interface module through the bidirectional connection; the security module is in communication connection with other modules, and the security module establishes unidirectional or bidirectional connection with other modules so as to ensure confidentiality and integrity of data transmission.
In this embodiment, the sensor module includes an optical sensor and an electrochemical sensor for measuring physical or chemical properties in the sample, generating raw data;
the optical sensor is used for analyzing the concentration of a compound in a solution during molecular detection, including DNA sequencing, protein measurement and fluorescence signal emitted by a sample under excited light during fluorescence detection, and is used for detecting the compound separated on a chromatographic column by fluorescence emitted by a small molecule or a biological molecule marked after excited light is received, and realizing separation and identification of different components in a mixture by detecting the absorption condition of different compounds to light with specific wavelength during chromatographic analysis;
applications of electrochemical sensors in molecular detection data analysis systems include pH measurement and oxygen measurement.
In this embodiment, the data acquisition and preprocessing module includes a data acquisition unit and a preprocessing unit;
the data acquisition and preprocessing module acquires the original data output by the sensor into the system through the data acquisition unit, so that high-speed and accurate data acquisition is realized, and high-quality input is ensured;
the high-speed acquisition of the original data output by the sensor is realized through the data acquisition unit, and in the small molecular detection, certain reactions or events occur very rapidly, so that the high-speed data acquisition is required to ensure that key information is not missed, and the requirements for accurately measuring the key parameters of the concentration and the reaction rate of the substance are met.
The data acquisition and preprocessing module performs signal amplification, filtering and correction processing on the original data through the preprocessing unit, ensures the quality of the acquired data, and prepares the data for subsequent analysis;
in small molecular detection, some detection signals are weaker, the signal to noise ratio is improved through signal amplification, so that the detection result is more stable and reliable, the definition and the readability of data are improved through filtering processing under the influence of environmental interference or noise of the sensor, the sensor has drift or nonlinear characteristics in the use process, the obtained data are consistent with the actual situation through correction, different sensors output data in different formats, and a preprocessing unit converts the data into a unified data format, so that the subsequent data analysis and algorithm processing are facilitated.
In this embodiment, the data processing analysis module includes a data processing software unit and a data analysis algorithm unit;
the data processing analysis module processes data through the data processing software unit, performs denoising, correction and alignment operation, provides deep processing on the data, and optimizes the data quality;
the data processing and analyzing module utilizes the algorithm to interpret and analyze the data through the data analyzing algorithm unit, extracts information about small molecules, and can accurately identify and quantify target molecules.
In this embodiment, the user interface module includes a GUI element;
the user interface module provides a user-friendly interface through the GUI unit, displays real-time data, controls experiments and visualizes results, is visual and easy to use, and is convenient for user operation and monitoring;
displaying data generated in the experiment in a graphical form through the GUI unit, so that a user can monitor the progress of the experiment and the change of the data in real time;
buttons and sliding block controls are provided through the GUI unit, so that a user can conveniently control the experiment to be carried out, and experimental conditions are adjusted to meet specific requirements;
through the GUI unit, the experimental result is graphically or graphically displayed, so that a user is helped to better understand the data, the trend and the mode;
the GUI unit collects user input through various input controls, and simultaneously provides feedback through prompt and popup modes, so that interactivity between the system and a user is improved.
In this embodiment, the report and export module includes a report generating unit and a data export unit;
the report and export module automatically generates an experiment result report through the report generating unit, wherein the report and export module comprises analysis parameters, charts and conclusions, and generates clear and detailed experiment results, so that the user can understand the experiment results conveniently.
The reporting and exporting module allows a user to export data to other analysis tools through the data exporting unit, supports further research and sharing, provides flexible data exporting options, and accords with industry standards.
In this embodiment, the standardization module is used to implement industry standard, ensure interoperability of the system with other devices and software, and ensure seamless integration of the system by adopting internationally approved data exchange standard and communication protocol;
specifically, firstly, determining a format standard of data transmission and storage in a system, defining and implementing industry-accepted data format standard by a standardized module, ensuring that data can be correctly interpreted and processed among different modules, then selecting and implementing a standard protocol for communication among the modules, and ensuring that all parts in the system communicate through a unified communication protocol, thereby realizing seamless communication among devices;
in a small molecular detection data analysis system, the application of a standardized module ensures the expandability and flexibility of the system, so that the system can be integrated with equipment of different suppliers and other software systems.
In this embodiment, the update module is configured to provide a periodic update mechanism for system firmware and software, adapt to new technologies and algorithms, implement remote firmware/software update functions, and ensure continuous system update.
In this embodiment, the security module is used to implement data encryption, authentication and access control, to ensure confidentiality and integrity of data, and to ensure data security and user privacy by using encryption algorithm, multi-level authentication and authority control;
specifically, encryption is carried out on data in the transmission process through an SSL secure transmission protocol, in a small molecular detection system, encryption is carried out through a transmission layer, experimental data is ensured not to be accessed or tampered by unauthorized parties in the transmission process from a sensor to an analysis module, encryption is carried out on the data stored in the system, confidentiality is ensured to be maintained even if a data storage medium is stolen, the small molecular detection system contains sensitive experimental data, and the data storage encryption prevents unauthorized access and data leakage;
in a small molecular detection system, RBAC is used for limiting different access rights of common users and administrators to the system, protecting the system from unauthorized access and operation, implementing multi-level two-factor authentication, requiring user name and password provision, and authenticating through mobile phone authentication code or biological recognition, so as to ensure that only authorized users can access the system, manage the rights of different users, ensure that they can only access the required functions and data, and user rights management ensures that each user can only access the data and functions within the rights range.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations may be made therein without departing from the spirit and scope of the invention as defined by the appended claims and their equivalents.

Claims (9)

1. The small molecular detection data analysis system comprises a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report deriving module, a standardization module, an updating module and a security module, and is characterized in that:
the system comprises a sensor module, a data acquisition preprocessing module, a data processing analysis module, a user interface module, a report deriving module, a standardization module, an updating module and a security module, wherein the sensor module, the data acquisition preprocessing module, the data processing analysis module, the user interface module, the report deriving module, the standardization module and the updating module are in communication connection;
the sensor module is connected with the data acquisition preprocessing module in a unidirectional way, and transmits the original data to the data acquisition preprocessing module in a unidirectional way for subsequent processing;
the data acquisition preprocessing module is connected with the data processing analysis module in a unidirectional way, and transmits the processed data to the data processing analysis module in a unidirectional way for further analysis;
the data processing analysis module is connected with the user interface module in a bidirectional way, and transmits an analysis result to the user interface module and receives input and control commands of the user interface module;
the user interface module is connected with the report export module in a unidirectional way, the user interface module transmits an export request to the report export module in a unidirectional way, and the report export module sends a generated report to the user interface module;
the data processing analysis module is connected with the report deriving module in a one-way, and sends an analysis result to the report deriving module to trigger report generation;
the user interface module is in bidirectional connection with the data export module, exchanges information with the data export module through the bidirectional connection, sends export requests, and transmits exported data;
the standardized module is connected with the data processing and analyzing module in a one-way, and sends standardized information to the data processing and analyzing module so as to ensure the compatibility of the system and industry standards;
the user interface module sends an update request to the update module through the bidirectional connection, and the update module sends update information to the user interface module through the bidirectional connection;
the security module is in communication connection with other modules, and the security module establishes unidirectional or bidirectional connection with the other modules so as to ensure confidentiality and integrity of data transmission.
2. The small molecule assay data analysis system of claim 1, wherein:
the sensor module includes an optical sensor and an electrochemical sensor for measuring a physical or chemical property in a sample, generating raw data.
3. The small molecule assay data analysis system of claim 2, wherein:
the data acquisition and preprocessing module comprises a data acquisition unit and a preprocessing unit;
the data acquisition and preprocessing module acquires the original data output by the sensor to the system through the data acquisition unit;
the data acquisition and preprocessing module performs signal amplification, filtering and correction processing on the original data through the preprocessing unit.
4. A small molecule assay data analysis system according to claim 3, wherein:
the data processing analysis module comprises a data processing software unit and a data analysis algorithm unit;
the data processing analysis module processes data through the data processing software unit and performs denoising, correction and alignment operations;
the data processing and analyzing module utilizes an algorithm to interpret and analyze data through a data analyzing algorithm unit.
5. The small molecule assay data analysis system of claim 4, wherein:
the user interface module includes a GUI element;
the user interface module provides a user-friendly interface through the GUI unit, real-time data display, experimental control and result visualization.
6. The small molecule assay data analysis system of claim 5, wherein:
the report and export module comprises a report generating unit and a data export unit;
the report and export module automatically generates an experiment result report through a report generating unit;
the reporting and export module provides flexible data export options by allowing a user to export data to other analysis tools through a data export unit.
7. The small molecule assay data analysis system of claim 6, wherein:
the standardized module is used for implementing industry standards and ensuring interoperability of the system with other devices and software.
8. The small molecule assay data analysis system of claim 7, wherein:
the updating module is used for providing a periodic updating mechanism of system firmware and software, adapting to new technology and algorithm and implementing remote firmware/software updating function.
9. The small molecule assay data analysis system of claim 8, wherein:
the security module is used for implementing data encryption, identity verification and access control, and uses an encryption algorithm, multi-level identity verification and authority control.
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