CN117404729A - Internal closed rotary air sterilizing and cleaning filter - Google Patents

Internal closed rotary air sterilizing and cleaning filter Download PDF

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Publication number
CN117404729A
CN117404729A CN202210793599.3A CN202210793599A CN117404729A CN 117404729 A CN117404729 A CN 117404729A CN 202210793599 A CN202210793599 A CN 202210793599A CN 117404729 A CN117404729 A CN 117404729A
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CN
China
Prior art keywords
sterilizing
laboratory
gas
disinfection
disinfectant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210793599.3A
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Chinese (zh)
Inventor
梅澍
董峰
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Individual
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Individual
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Priority to CN202210793599.3A priority Critical patent/CN117404729A/en
Publication of CN117404729A publication Critical patent/CN117404729A/en
Pending legal-status Critical Current

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Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F7/00Ventilation
    • F24F7/003Ventilation in combination with air cleaning
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F13/00Details common to, or for air-conditioning, air-humidification, ventilation or use of air currents for screening
    • F24F13/28Arrangement or mounting of filters
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F7/00Ventilation
    • F24F7/007Ventilation with forced flow
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F8/00Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying
    • F24F8/10Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by separation, e.g. by filtering
    • F24F8/108Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by separation, e.g. by filtering using dry filter elements
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F8/00Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying
    • F24F8/20Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by sterilisation
    • F24F8/24Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by sterilisation using sterilising media
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F8/00Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying
    • F24F8/30Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by ionisation

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

The International Patent Classification (IPC) is classified as part of human life needs, medical technology a 61L. The invention designs an internal closed rotary disinfection and sterilization filter device aiming at the defects of the ventilation and exhaust system of the current enhanced biosafety laboratory (BSL-2 class laboratory). The box type clean filter device is adopted, and a novel composite disinfectant is arranged in the filter device to replace the filter membrane at the tail end of ventilation and exhaust in the laboratory at present. Can kill all types of microorganisms including spores, bacterial spores, fungal spores, radiobacteria, mycobacteria, yeasts, enzymes, viruses. The possibility of pollution to the laboratory environment caused by backflow of waste gas due to the change of laboratory pressure caused by blockage of a filter membrane by dust particles in the atmosphere is avoided. It is also used in the ventilation and exhaust system of hospital infectious disease ward, biomedical laboratory and production workshop and various indoor people gathering and activity places.

Description

Internal closed rotary air sterilizing and cleaning filter
Technical Field
The invention relates to an exhaust tail gas disinfection and filtration device of a reinforced biosafety laboratory (BSL-2 class laboratory). The classification belongs to the human living needs department according to the International Patent Classification (IPC), and relates to the A61L class of medical technology.
Background
The enhanced biosafety laboratory (BSL-2 class laboratory) is widely used in medical, scientific and biotechnology. By amplifying genes in the virus body through in vitro simulation of DNA replication process, viruses with low content can be detected. Is an important detection method for detecting virus infectious diseases in clinic, such as AIDS, hepatitis B, highly pathogenic respiratory viruses and the like. During the detection process, aerosol containing virus nucleic acid particles is generated, and key operation steps such as laboratory safety, nucleic acid extraction and the like are all carried out in a biosafety cabinet. The air in the laboratory and the biosafety cabinet is exhausted outdoors through an exhaust system, most of the laboratory at present adopts a mechanical ventilation system, and the system is used for controlling the air supply and exhaust proportion and maintaining the negative pressure requirement of each room so as to ensure the experiment. The air flow in the chamber is directed from the "clean" area to the "contaminated" area. The laboratory air supply system can be provided with primary, medium and high-efficiency tertiary air filtration, and the primary and medium-efficiency filters can play a role in prefiltering. The main method for reducing the emission of air pollution is to add a three-stage filtering membrane at the tail end of the exhaust gas so as to reduce the leakage of laboratory pathogens. Many laboratories do not have high efficiency filtration membranes or do not change filtration membranes for long periods, especially in public places. In particular, the nucleic acid fragments of the virus are too tiny and can penetrate through the high-efficiency filter to be discharged outside under the air pressure of the air compressor of the ventilation system. This can cause the pathogenic microorganisms to be directly discharged into the outdoor environment. In addition, in sand storm weather, the high-efficiency filtering membrane of the ventilation system is blocked, so that the negative pressure gradient of a laboratory is changed, the air flow cannot flow directionally, and polluted gas can flow back into the room, so that the experiment cannot be performed normally. Meanwhile, in order to cope with tiny pathogenic microorganisms, the high-efficiency filtering membrane has to be designed too densely, dust particles in the environment are easier to block the high-efficiency filtering membrane, and although the filtering device is improved and the adsorbent capable of adsorbing virus pathogenic microorganisms is added, the blocking of the filtering membrane caused by the dust particles and the like still cannot be solved. Floating landings in the environment cause infection and transmission around and to the population.
Not only are ventilation and exhaust systems of strong biosafety laboratories (BSL-2 class laboratories), hospital infectious disease wards, biomedical laboratories and production workshops, and various places where people gather and move in a room, but also the same problems are faced.
Disclosure of Invention
1. The invention solves the technical problems that:
the end of the ventilation system is additionally provided with the inner closed rotary type exhaust device designed by the invention, so that the exhaust mode of the filtering membrane device system of the ventilation exhaust system for the exhaust gas of the current enhanced biosafety laboratory (BSL-2 class) is replaced. The discharged gas is discharged outdoors after being disinfected and cleaned by the inner closed rotary disinfectant and then is discharged into the air environment, so that the pollution and dispersion of the outdoor environment air caused by the overflow of pathogens are prevented. The danger of pollution to the laboratory environment caused by backflow of waste gas due to the change of laboratory pressure caused by the blockage of the filter membrane by dust particles in the atmosphere is avoided.
2. The invention adopts the technical scheme that:
the main body part of the internal closed rotary air sterilizing and cleaning filter device comprises: the sterilizing box consists of an externally hung box body, an inner sterilizing liquid box body, an air inlet pipe and an exhaust pipe as main components.
The box body of the disinfection composite solution is divided into two layers, the outer layer is a protective layer of the device, and the inner layer is a disinfection composite solution liner box body. The liner box Cheng Luan is round, the lower 2/3 space is filled with sterilizing solution, and the upper 1/3 space is a flowing gas sterilizing space formed by the sterilizing solution. The arc-shaped baffle plate is additionally arranged in the box body and on the opposite side of the air supply pipe opening. The gas discharged from the laboratory is sent into the sterilizing liquid in the box body and then is pushed by wind pressure, and directly enters the sterilizing liquid of the lower 2/3. The gas and the disinfection liquid are subjected to resistance to form vortex backflow, and in the process of vortex backflow, the collision frequency between molecules of the disinfection liquid and microbial pathogens is increased under the influence of the intense vortex swirling motion of the airflow, so that the disinfection and sterilization effect is improved, and the disinfection and sterilization process of the first stage is completed.
After the first-stage disinfection and sterilization is completed by the disinfectant, the gas rises to a 1/3 closed space on the liner box body in the disinfectant through vortex backflow under the action of the air pressure of the supplied air, and as the disinfectant is influenced by vortex flow, aerosol is formed in the disinfectant in the closed space, and the rising air completes the second-stage disinfection and sterilization through the sterilized aerosol space. Thereby realizing the purpose that the laboratory finally discharges clean gas outdoors.
The present invention relates to a rotary internal closed gas sterilizing and cleaning device, and is characterized by that it adopts a new type sterilizing and disinfecting technology, and adopts sterilizing and cleaning agent, and is colorless, odorless, foamless, impurity-free and liquid. The liquid state is stable in normal temperature storage. The pH was 7.2. Detecting the heavy metal content of the disinfectant: the lead, arsenic and mercury contents were 0 mg/kg (zero detection). The disinfectant is a multicomponent disinfectant, has long-term effect by synergistic micro action, is completely decomposed into oxygen and water after the disinfectant acts, and does not generate any disinfection byproducts or other toxic and harmful substances. The health of human body is not endangered, and the environmental pollution is not caused. In the use process, the sterilization is thorough, colorless and odorless, high-efficiency sterilization is realized, the sterilization is rapid and safe without residues, the sterilization performance is stable, the sterilization is not influenced by environment ph, temperature and illumination, microorganisms are thoroughly killed, and spores can be killed within 3-5 minutes. The sterilization effect is rapid, and the time is greatly saved, thereby improving the biological effect of sterilization. Meets the requirements of GMP production environment conditions on aseptic medicine production.
Drawings
FIG. 1 is a schematic illustration of a ventilation and exhaust system for a current enhanced biosafety laboratory (BSL-class 2 laboratory) operating environment. The exhaust design of all biosafety cabinets is that the ventilation and exhaust air-conditioning main laboratory is that the polluted air in the laboratory and the safety cabinet is directly discharged to the outdoor environment air through an exhaust outlet for delivering the polluted air from the opposite side up and down, and the main method for reducing the air pollution emission is that a three-stage filtering membrane is added at the tail end of the exhaust so as to reduce the leakage of pathogens in the laboratory.
FIG. 2 is a schematic illustration of the addition of this gas at the exhaust end of an enhanced biosafety laboratory (BSL-2 type laboratory). The invention is used to replace the prior filtering device with the inner closed rotary gas sterilizing and cleaning device, so that the gas exhausted from the laboratory directly enters the sterilizing liquid of the sterilizing and cleaning device along with pathogenic microorganisms, and is discharged outside after sterilizing and cleaning.
FIG. 3 is a schematic illustration of the structural design of the internal closed rotary air sterilizing and cleaning filter device: the invention relates to a rotary inner closed gas disinfection and cleaning device, wherein a box body of a disinfection composite solution is divided into two layers, the outer layer is a protective layer of the device, and the inner layer is a disinfection composite solution liner box body; the sterilizing solution is filled in the lower 2/3 space, and the upper 1/3 space is a flowing gas sterilizing space formed by the sterilizing solution. The exhaust air of the laboratory directly enters the lower 2/3 disinfectant, and the exhaust gas of the laboratory directly passes through the disinfectant to form the first-stage disinfectant. After the first-stage disinfection and sterilization is completed by the disinfectant, the gas rises to 1/3 of the flowing gas sterilization space in the box body to perform the second-stage air sterilization and sterilization, thereby realizing the purpose that the laboratory finally discharges clean gas outdoors, (1) the ventilation air supply pipe of the central air-conditioning air compressor laboratory. (2) Ventilation and air supply for laboratory of central air conditioner. (3) The air inlet pipeline is connected with the box body joint. (4) Laboratory gas filtration box. (5) The disinfectant is forced by the gas pressure to form a swirling fluid. (6) Silver hydrogen peroxide ion composite solution bin. (7) The exhaust pipe is connected with the box body joint. (8) Laboratory ventilation exhaust duct. (9) And (3) sterilizing, filtering air and discharging gas. A circular arc baffle. And atomizing the silver hydroxide ion composite solution. Silver hydrogen peroxide ion composite solution.
FIG. 4 is a dimension and specification design drawing of the internal closed rotary air sterilizing and cleaning filter device.

Claims (4)

1. The exhaust system of the current enhanced biosafety laboratory (BSL-2 type laboratory) is changed into the inner closed rotary exhaust device designed by the invention in a mode of adding the high-efficiency filtering membrane at the tail end, so that the gas containing various pathogenic microorganisms discharged from the laboratory is thoroughly disinfected and cleaned by the device and then is discharged into the air environment, and meanwhile, the laboratory pollution caused by the reverse flow of the waste gas caused by the change of the negative pressure gradient of the laboratory due to the blocking of the filtering membrane by dust particles in the dust weather is avoided.
2. The internal-closed rotary sterilizing and disinfecting filter device is characterized in that a box body of a sterilizing composite solution is divided into two layers, the outermost layer is protected by the device, the inner layer is a container box body for containing the sterilizing composite solution, the inner layer is divided into an upper part and a lower part, the lower part is 2/3 of the sterilizing solution, the upper part is 1/3 of the sterilizing solution, the flowing gas sterilizing space formed by the sterilizing solution is the upper part, the gas exhausted from a laboratory directly enters the lower part to form a first-stage sterilizing solution, the gas after the first-stage sterilizing and disinfecting is completed by the sterilizing solution rises to the flowing gas sterilizing space of the upper part of 1/3 in the box body, the second-stage sterilizing can be performed, and the gas is finally exhausted out of the room by the wind pressure of a ventilation system after the second-stage sterilizing, so that the aim of thoroughly sterilizing the gas containing pathogenic microorganisms in the laboratory and then cleanly discharging the gas through the device is realized.
3. The internal closed rotary sterilizing and disinfecting filter device as claimed in claim 1, wherein; the inner container box body of the invention is in an oval volume, and the circular arc baffle plate is additionally arranged at the opposite side of the opening of the air supply pipe in the box body, which is characterized in that: the gas is pushed by wind pressure after being sent into the sterilizing liquid in the box body, vortex backflow is formed along with the resistance of the circular arc baffle plate on the sterilizing liquid, the sterilizing and disinfecting time of the gas and the sterilizing liquid is prolonged in the process of vortex backflow, meanwhile, the collision frequency between the molecules of the sterilizing liquid and pathogenic microorganisms is increased under the influence of the severe vortex swirling motion of the gas flow, and the sterilizing and disinfecting effect is improved.
4. Because the disinfectant is influenced by vortex flow, aerosol is formed in the disinfectant in 1/3 of the closed space on the liner box body, under the effect of the pressure gradient of the negative pressure laboratory, the gas rises to the closed space through the vortex backflow of the disinfectant, and the rising air completes secondary disinfection and sterilization through the disinfected aerosol space, and the invention adopts a novel and composite disinfection cleaner according to the claim 1, which is characterized in that: can kill all types of microorganisms including spores, bacterial spores, fungal spores, radiobacteria, mycobacteria, saccharomycetes, enzyme bacteria and viruses, and experimental data show that the method can be used for killing all types of microorganisms including spores, bacterial spores, fungal spores, radiobacteria, mycobacteria, saccharomycetes, enzyme bacteria and viruses; the bacillus killing rate can reach 4-6 logs within 3-5 minutes, various microorganisms (including spores) can be killed or the propagation of microorganisms can be inhibited in GMP space and object surface disinfection, so that monitoring of planktonic bacteria and sedimentation bacteria is not out of standard, the bacillus killing agent has high-efficiency disinfection effect within the range of 0-95 ℃, chemical components of the bacillus killing agent act on cell membranes, proteins forming bacteria are destroyed with strong oxidizing property, active free radicals are generated under the action of metal ions, cell walls are attacked, cell structures and functions are destroyed, viral DNA and RNA stop replicating and cell metabolism are stopped, and experimental results show that: the disinfectant has good disinfection effect on bacteria and viruses, belongs to non-toxic substances, has no irritation to the whole skin of animals, has strong killing effect on microbial pathogens, has stable performance and low corrosiveness, and the disinfectant cleaner adopted by the disinfectant has long-term effect, is completely decomposed into oxygen and water after the disinfectant is acted, does not generate any disinfection byproducts or other toxic and harmful substances, does not harm the health of human bodies, does not cause environmental pollution, has thorough disinfection, is colorless and odorless, has high-efficiency disinfection, is fast, safe and residue-free, has stable disinfection performance, is not easily influenced by environmental pH, temperature and illumination, thoroughly kills microorganisms, kills spores within 3-5 minutes, has rapid disinfection effect, greatly saves time, thereby improving the biological effect of disinfection and sterilization, and meeting the requirements of GMP production environmental conditions on aseptic drug production.
CN202210793599.3A 2022-07-07 2022-07-07 Internal closed rotary air sterilizing and cleaning filter Pending CN117404729A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210793599.3A CN117404729A (en) 2022-07-07 2022-07-07 Internal closed rotary air sterilizing and cleaning filter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210793599.3A CN117404729A (en) 2022-07-07 2022-07-07 Internal closed rotary air sterilizing and cleaning filter

Publications (1)

Publication Number Publication Date
CN117404729A true CN117404729A (en) 2024-01-16

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ID=89493068

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210793599.3A Pending CN117404729A (en) 2022-07-07 2022-07-07 Internal closed rotary air sterilizing and cleaning filter

Country Status (1)

Country Link
CN (1) CN117404729A (en)

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