CN117398609A - Brain stimulation regulation and control device, method, terminal and storage medium - Google Patents

Brain stimulation regulation and control device, method, terminal and storage medium Download PDF

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CN117398609A
CN117398609A CN202311726775.2A CN202311726775A CN117398609A CN 117398609 A CN117398609 A CN 117398609A CN 202311726775 A CN202311726775 A CN 202311726775A CN 117398609 A CN117398609 A CN 117398609A
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CN117398609B (en
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姚乃琳
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Hangzhou Boyi Technology Co ltd
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    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36135Control systems using physiological parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36135Control systems using physiological parameters
    • A61N1/36139Control systems using physiological parameters with automatic adjustment

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Abstract

The invention discloses a brain stimulation regulation and control device, a brain stimulation regulation and control method, a terminal and a storage medium, and relates to the technical field of device control. The device comprises: the global detection module is used for acquiring global signal cooperativity of a plurality of brain areas of the target user; the global judging module is used for judging whether brain stimulation is carried out on the target user according to global signal cooperativity; the local detection module is used for acquiring local signal synchronicity corresponding to each brain area if brain stimulation is carried out; and the brain region screening module is used for screening out a target brain region to be stimulated according to the local signal synchronism of each brain region, and regulating and controlling a brain stimulation instrument used by a target user according to the target brain region. According to the brain wave data analysis method and the brain wave data analysis device, the brain wave data of the user are analyzed together from the global level and the local level, so that objective and accurate regulation and control of a brain stimulation instrument can be realized. Solves the problems that the transcranial electric stimulation instrument in the prior art is usually regulated and controlled according to subjective judgment and experience guidance of professionals, and objective and accurate regulation and control are difficult to realize.

Description

Brain stimulation regulation and control device, method, terminal and storage medium
Technical Field
The present invention relates to the field of device control technologies, and in particular, to a brain stimulation control device, a brain stimulation control method, a brain stimulation control terminal, and a brain stimulation control storage medium.
Background
The transcranial electrical stimulation technology has the characteristics of high safety, small side effect and convenient operation, and becomes a research hot spot for brain neurologists in recent years. At present, the transcranial electric stimulation instrument is regulated and controlled according to subjective judgment and experience guidance of professionals, and objective and accurate regulation and control are difficult to realize.
Accordingly, there is a need for improvement and development in the art.
Disclosure of Invention
The invention aims to solve the technical problems that the prior art is difficult to realize objective and accurate regulation and control by providing a brain stimulation regulation and control device, a method, a terminal and a storage medium according to the defects of the prior art, and aims to solve the problems that a transcranial electric stimulation instrument in the prior art is usually regulated and controlled according to subjective judgment and experience guidance of professionals.
The technical scheme adopted by the invention for solving the problems is as follows:
in a first aspect, an embodiment of the present invention provides a brain stimulation modulation device, the device comprising:
the global detection module is used for acquiring global signal cooperativity of a plurality of brain areas of a target user, wherein the global signal cooperativity is calculated based on first brain wave data acquired by each brain area;
the global judging module is used for judging whether brain stimulation is carried out on the target user according to the global signal cooperativity;
the local detection module is used for acquiring local signal synchronicity corresponding to each brain region if brain stimulation is carried out, wherein the local signal synchronicity of each brain region is calculated based on second brain wave data acquired by a plurality of sites in the brain region;
and the brain region screening module is used for screening out a target brain region to be stimulated according to the local signal synchronism of each brain region, and regulating and controlling a brain stimulation instrument used by the target user according to the target brain region.
In one embodiment, the global detection module includes:
the brain region comparison unit is used for calculating signal cooperativity between every two brain regions according to the first brain wave data;
and the cooperativity calculation unit is used for calculating the global signal cooperativity according to each signal cooperativity.
In one embodiment, the global determination module includes:
the threshold determining unit is used for acquiring the user information of the target user and determining a synergy threshold according to the user information;
the execution judging unit is used for performing brain stimulation if the global signal cooperativity is smaller than the cooperativity threshold value; if the global signal synergy is greater than or equal to the synergy threshold, no brain stimulation is performed.
In one embodiment, the local detection module comprises:
the characteristic acquisition unit is used for acquiring oscillation characteristic data corresponding to each second brain wave data respectively;
a similarity calculation unit configured to calculate oscillation similarity of each of the second brain wave data based on each of the oscillation feature data;
and the synchronicity calculating unit is used for determining the synchronicity of the local signals according to the oscillation similarity.
In one embodiment, the brain region screening module comprises:
and the synchronicity comparison unit is used for determining the target brain region according to the brain region with the minimum synchronicity of the local signals.
In one embodiment, the brain region screening module further comprises:
the parameter determining unit is used for determining a stimulation parameter combination according to the target brain region and regulating and controlling the brain stimulation instrument according to the stimulation parameter combination;
the timing detection unit is used for acquiring the global signal cooperativity again after the operation time length of the brain stimulation instrument reaches the preset time length;
judging whether brain stimulation is carried out on the target user according to the global signal cooperativity;
if brain stimulation is carried out, continuing to execute the step of acquiring the synchronicity of local signals corresponding to each brain region;
and if the brain stimulation is not performed, controlling the brain stimulation instrument to stop running.
In one embodiment, the brain stimulation device is a transcranial alternating current stimulation device.
In a second aspect, embodiments of the present invention further provide a brain stimulation modulation method, the method comprising:
acquiring global signal cooperativity of a plurality of brain regions of a target user, wherein the global signal cooperativity is calculated based on first brain wave data acquired by each brain region;
judging whether brain stimulation is carried out on the target user according to the global signal cooperativity;
if brain stimulation is carried out, local signal synchronicity corresponding to each brain region is obtained, wherein the local signal synchronicity of each brain region is calculated based on second brain wave data acquired by a plurality of sites in the brain region;
and screening out a target brain region to be stimulated according to the local signal synchronism of each brain region, and regulating and controlling a brain stimulation instrument used by the target user according to the target brain region.
In a third aspect, an embodiment of the present invention further provides a terminal, where the terminal includes a memory and more than one processor; the memory stores more than one program; the program comprises instructions for performing a brain stimulation modulation method as described above; the processor is configured to execute the program.
In a fourth aspect, embodiments of the present invention also provide a computer readable storage medium having stored thereon a plurality of instructions adapted to be loaded and executed by a processor to implement the steps of the brain stimulation modulation method described above.
The invention has the beneficial effects that: according to the embodiment of the invention, the brain wave data of the user are analyzed together from the global level and the local level, so that objective and accurate regulation and control of the brain stimulation instrument can be realized. Solves the problems that the transcranial electric stimulation instrument in the prior art is usually regulated and controlled according to subjective judgment and experience guidance of professionals, and objective and accurate regulation and control are difficult to realize.
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In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required to be used in the embodiments or the description of the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present invention, and other drawings may be obtained according to the drawings without inventive effort to those skilled in the art.
Fig. 1 is a schematic block diagram of a brain stimulation control device according to an embodiment of the present invention.
Fig. 2 is a schematic flow chart of a brain stimulation control method according to an embodiment of the present invention.
Fig. 3 is a schematic block diagram of a terminal according to an embodiment of the present invention.
Detailed Description
The invention discloses a brain stimulation regulation and control device, a brain stimulation regulation and control method, a terminal and a storage medium, and in order to make the purposes, the technical scheme and the effects of the invention clearer and more specific, the invention is further described in detail below by referring to the accompanying drawings and the embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
As used herein, the singular forms "a", "an", "the" and "the" are intended to include the plural forms as well, unless expressly stated otherwise, as understood by those skilled in the art. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof. It will be understood that when an element is referred to as being "connected" or "coupled" to another element, it can be directly connected or coupled to the other element or intervening elements may also be present. Further, "connected" or "coupled" as used herein may include wirelessly connected or wirelessly coupled. The term "and/or" as used herein includes all or any element and all combination of one or more of the associated listed items.
It will be understood by those skilled in the art that all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs unless defined otherwise. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the prior art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
In view of the above-mentioned drawbacks of the prior art, the present invention provides a brain stimulation control device, comprising: the global detection module is used for acquiring global signal cooperativity of a plurality of brain areas of a target user, wherein the global signal cooperativity is calculated based on first brain wave data acquired by each brain area; the global judging module is used for judging whether brain stimulation is carried out on the target user according to the global signal cooperativity; the local detection module is used for acquiring local signal synchronicity corresponding to each brain region if brain stimulation is carried out, wherein the local signal synchronicity of each brain region is calculated based on second brain wave data acquired by a plurality of sites in the brain region; and the brain region screening module is used for screening out a target brain region to be stimulated according to the local signal synchronism of each brain region, and regulating and controlling a brain stimulation instrument used by the target user according to the target brain region. According to the brain wave data analysis method and the brain wave data analysis device, the brain wave data of the user are analyzed together from the global level and the local level, so that objective and accurate regulation and control of a brain stimulation instrument can be realized. Solves the problems that the transcranial electric stimulation instrument in the prior art is usually regulated and controlled according to subjective judgment and experience guidance of professionals, and objective and accurate regulation and control are difficult to realize.
As shown in fig. 1, the apparatus includes:
the global detection module 01 is used for acquiring global signal cooperativity of a plurality of brain areas of a target user, wherein the global signal cooperativity is calculated based on first brain wave data acquired by each brain area.
In particular, the target user may be any user who has a need for using a brain stimulation device, such as a user who needs to use a transcranial alternating current stimulation device. In this embodiment, a plurality of brain wave acquisition units are provided in the brain stimulation apparatus in advance, each brain wave acquisition unit corresponds to a different brain region of the target user, and each brain wave acquisition unit is used for acquiring brain wave data of one brain region. In an actual application scene, when a target user starts a brain stimulation instrument, the brain stimulation instrument starts each brain wave acquisition unit first to acquire first brain wave data of each brain region. And then, calculating the global signal cooperativity of each brain region by analyzing the signal waveform cooperativity of each first brain wave data. It will be appreciated that there are differences in brain states for different users or groups of users, and that brain wave data for different brain regions may reflect the brain state differences, resulting in different numerical characteristics for global signal cooperativity for different users or groups of users. The better the brain state, the stronger its global signal cooperativity, and conversely the weaker.
In one implementation, the global detection module 01 includes:
the brain region comparison unit is used for calculating signal cooperativity between every two brain regions according to the first brain wave data;
and the cooperativity calculation unit is used for calculating the global signal cooperativity according to each signal cooperativity.
Specifically, after the first brain wave data of each brain region is acquired, the first brain wave data are combined two by two, and signal cooperativity is calculated. For example, first brain wave data a, b, c corresponding to the brain regions A, B, C are currently acquired. Calculation of Signal cooperativity X of a and b 1 Signal cooperativity X of a and c 2 Calculating the signal cooperativity X of b and c 3 Then calculate X 1 、X 2 、X 3 Global signal cooperativity of brain region A, B, C is determined from the average value. The signal cooperativity can reflect the communication state between two brain regions, so that the communication state of the whole brain can be analyzed from the global situation through the signal cooperativity between every two brain regions, and the global signal cooperativity can be calculated.
In one implementation, the method of calculating the signal cooperativity between two of the brain regions includes:
calculating the phase-amplitude coupling degree between the two first brain wave data according to the first brain wave data of the two brain regions;
and calculating the signal cooperativity of the two first brain wave data according to the phase-amplitude coupling degree.
In particular, the signal cooperativity between the two first brain wave data is evaluated by the phase-amplitude coupling condition. Taking two brain areas of the temporal lobe and the frontal lobe as an example, acquiring first brain wave data corresponding to the temporal lobe and the frontal lobe respectively, and detecting the phases of the two first brain wave data, wherein the amplitude of a high-frequency wave band (gamma wave band) of the temporal lobe of the young is consistent with the phase of an alpha wave band of the frontal lobe, and the phase-amplitude coupling degree is high, so that the signal cooperativity is strong; the elderly suffer from weak signal cooperativity due to low phase-amplitude coupling degree caused by nerve fracture and the like.
As shown in fig. 1, the apparatus further includes:
and the global judging module 02 is used for judging whether the brain stimulation is carried out on the target user according to the global signal cooperativity.
Specifically, the value of global signal cooperativity can reflect the current overall brain state of the target user, so as to judge whether the target user needs to optimize the brain state through brain stimulation.
In one implementation, the global determination module 02 includes:
the threshold determining unit is used for acquiring the user information of the target user and determining a synergy threshold according to the user information;
the execution judging unit is used for performing brain stimulation if the global signal cooperativity is smaller than the cooperativity threshold value; if the global signal synergy is greater than or equal to the synergy threshold, no brain stimulation is performed.
Specifically, the synergy threshold is a decision boundary that divides whether or not brain stimulation is performed, and since different users have individual differences, the present embodiment sets an appropriate synergy threshold specifically for the target user according to his or her user information. For example, the user information may include the age of the user, and the nerve break condition may become more severe with age, so that the nerve connection state of the young person is better than that of the old person, so that the older the user, the lower the synergy threshold. In an actual application scene, if the global signal cooperativity calculated by the target user at present is smaller than the cooperativity threshold value corresponding to the target user, the current brain state of the target user is required to be optimized through brain stimulation; if the global signal cooperativity calculated by the target user is greater than or equal to the cooperativity threshold value corresponding to the target user, the current brain state of the target user is indicated to be unnecessary to be optimized temporarily, and a brain stimulation instrument can be omitted.
As shown in fig. 1, the apparatus further includes:
the local detection module 03 is configured to obtain local signal synchronicity corresponding to each brain region if brain stimulation is performed, where the local signal synchronicity of each brain region is calculated based on second brain wave data acquired at a plurality of sites in the brain region.
Specifically, in this embodiment, a plurality of sites are provided in advance in each brain region, and each site is provided with a brain wave acquisition unit. For example, for each brain region, a brain wave acquisition unit is arranged at the central position of the brain region and is used for acquiring first brain wave data; and a plurality of brain wave acquisition units are circumferentially arranged around the central position of the brain region at preset distances and are used for acquiring second brain wave data. In an actual application scene, if a target user needs to optimize the brain state through brain stimulation at present, starting a brain wave acquisition unit of each site in each brain region to acquire a plurality of second brain wave data, and calculating signal synchronism by analyzing signal waveforms of the second brain wave data to acquire local signal synchronism of the brain region. Generally, the more normal a local state of a brain region is, the higher the synchronism of brain wave data acquired at different points of the brain region, i.e. the higher the local signal synchronism is, and vice versa.
In one implementation, the local detection module 03 includes:
the characteristic acquisition unit is used for acquiring oscillation characteristic data corresponding to each second brain wave data respectively;
a similarity calculation unit configured to calculate oscillation similarity of each of the second brain wave data based on each of the oscillation feature data;
and the synchronicity calculating unit is used for determining the synchronicity of the local signals according to the oscillation similarity.
Specifically, local signal synchronicity refers to the degree of similarity of brain wave data acquired at different points in the same brain region. The activity of the cerebral cortex is supported by various oscillations generated by the brain, and under normal conditions, waveform oscillations of a plurality of second brain wave data acquired by the same brain region have self-similarity, that is, oscillation characteristics are similar. The present embodiment calculates the oscillation similarity from the oscillation characteristic data of each second brain wave data. The higher the oscillation similarity, the stronger the local signal synchronicity in the brain region, and conversely the weaker.
In another implementation manner, the calculating the oscillation similarity of each of the second brain wave data according to each of the oscillation characteristic data includes:
judging whether the two oscillation characteristic data have phase locked oscillation behaviors or not according to the two oscillation characteristic data;
if the first numerical value exists, the first numerical value is used as the oscillation similarity of the corresponding second brain wave data;
if the first brain wave data does not exist, the second numerical value is used as the oscillation similarity of the corresponding second brain wave data, wherein the first numerical value is higher than the second numerical value;
and taking the average value of the oscillation similarity between every two second brain wave data as the oscillation similarity of the whole second brain wave data.
Specifically, the signal synchronism of the present embodiment is mainly to determine phase synchronization, that is, whether or not there is oscillation behavior of phase lock between two brain wave data. And judging whether the phases are synchronous or not by pairing the oscillation characteristic data, obtaining the oscillation similarity between the second brain wave data, and obtaining the overall oscillation similarity of all the second brain wave data by means of average value calculation.
As shown in fig. 1, the apparatus further includes:
and the brain region screening module 04 is used for synchronously screening out target brain regions to be stimulated according to the local signals of the brain regions, and regulating and controlling brain stimulation instruments used by the target users according to the target brain regions.
Specifically, the brain state of each brain region can be evaluated by the local signal synchronicity of the brain region, and the more normal the brain state of the brain region is, the higher the synchronicity of brain wave data acquired by different points of the brain region is, namely, the higher the local signal synchronicity is. Thus, the target brain region needing electric stimulation can be screened out by comparing the local signal synchronicity of each brain region. And accurately regulate and control the brain stimulation instrument according to the position and the category of the target brain region.
In one implementation, the brain region screening module 04 includes:
and the synchronicity comparison unit is used for determining the target brain region according to the brain region with the minimum synchronicity of the local signals.
Specifically, the local signal synchronicity may reflect the local brain state of the brain region, so the lower the local signal synchronicity, the higher the optimization requirement of the brain region is, and in this embodiment, the brain region with the lowest local signal synchronicity is selected for electrical stimulation by using the brain stimulation apparatus each time.
In one implementation, the brain region screening module 04 further includes:
the parameter determining unit is used for determining a stimulation parameter combination according to the target brain region and regulating and controlling the brain stimulation instrument according to the stimulation parameter combination;
the timing detection unit is used for acquiring the global signal cooperativity again after the operation time length of the brain stimulation instrument reaches the preset time length;
judging whether brain stimulation is carried out on the target user according to the global signal cooperativity;
if brain stimulation is carried out, continuing to execute the step of acquiring the synchronicity of local signals corresponding to each brain region;
and if the brain stimulation is not performed, controlling the brain stimulation instrument to stop running.
Specifically, the stimulation parameter combinations applicable to different brain regions are different, and the embodiment can preset the stimulation parameter combinations corresponding to different brain regions. In an actual application scene, corresponding stimulation parameter combinations are determined according to a target brain region, and a brain stimulation instrument is regulated and controlled to operate based on the stimulation parameter combinations. And after the preset time period, re-detecting the overall brain state of the target user to judge whether the brain stimulation is needed to be continued. If the brain stimulation is still needed to be continued, the brain state of the brain regions optimized by the brain stimulation instrument may be improved, so that the local signal synchronicity of each brain region needs to be re-acquired to determine the target brain region to be stimulated; if brain stimulation is not needed, the brain stimulation instrument is closed timely, and excessive stimulation to a target user is avoided.
In one implementation, the determining a stimulation parameter combination from the target brain region includes:
constructing a first stimulation waveform for optimizing the synchronism of local signals according to the second brain wave data corresponding to the target brain region;
constructing a second stimulation waveform for optimizing global signal cooperativity according to phase-amplitude coupling difference data between the first brain wave data of the target brain region and the first brain wave data of the non-target brain region;
obtaining an average value of local signal synchronicity of each brain region, and determining the stimulation intensity according to the difference value between the local signal synchronicity of the target brain region and the average value;
a combination of stimulation parameters for the target brain region is determined based on the first stimulation waveform, the second stimulation waveform, and the stimulation intensity.
Specifically, the stimulus parameter combination of the present embodiment is mainly determined by the stimulus waveform and the stimulus intensity. For the stimulus waveforms, the embodiment adopts a combination optimization form, and two stimulus waveforms are constructed to optimize global signal synergy and local signal synchronism respectively. The method is characterized in that the method is used for optimizing the synchronism of local signals and is a first stimulation waveform, and the optimization target of the first stimulation waveform is to improve the similarity of brain wave data acquired respectively by different points of the same brain region, so that the first stimulation waveform is constructed by analyzing second brain wave data acquired by different points of the target brain region; the second stimulation waveform is used for optimizing the local signal synchronism, and the second stimulation waveform is constructed by analyzing the phase-amplitude coupling difference between the first brain wave data of the target brain region and the other brain regions because the second stimulation waveform is optimized to improve the phase-amplitude coupling degree of the brain wave data acquired by the target brain region and the other brain regions respectively.
Based on the above embodiment, the present invention further provides a brain stimulation regulation method, as shown in fig. 2, including:
step S100, acquiring global signal cooperativity of a plurality of brain areas of a target user, wherein the global signal cooperativity is calculated based on first brain wave data acquired by each brain area;
step 200, judging whether brain stimulation is performed on the target user according to the global signal cooperativity;
step S300, if brain stimulation is performed, local signal synchronicity corresponding to each brain region is obtained, wherein the local signal synchronicity of each brain region is calculated based on second brain wave data acquired by a plurality of sites in the brain region;
step 400, screening out a target brain region to be stimulated according to the local signal synchronism of each brain region, and regulating and controlling a brain stimulation instrument used by the target user according to the target brain region.
In one implementation, the method for calculating global signal cooperativity includes:
calculating signal cooperativity between every two brain areas according to the first brain wave data;
and calculating the global signal cooperativity according to each signal cooperativity.
In one implementation, the determining whether to perform brain stimulation on the target user according to the global signal cooperativity includes:
acquiring user information of the target user, and determining a synergy threshold according to the user information;
if the global signal cooperativity is smaller than the cooperativity threshold value, brain stimulation is carried out;
if the global signal synergy is greater than or equal to the synergy threshold, no brain stimulation is performed.
In one implementation, the method for calculating the local signal synchronicity includes:
acquiring oscillation characteristic data corresponding to each second brain wave data respectively;
calculating the oscillation similarity of each second brain wave data according to each oscillation characteristic data;
and determining the local signal synchronism according to the oscillation similarity.
In one implementation, the screening the target brain region to be stimulated according to the local signal synchronicity of each brain region includes:
and determining the target brain region according to the brain region with the minimum local signal synchronism.
In one implementation, the brain stimulation apparatus for regulating the use of the target user according to the target brain region includes:
determining a stimulation parameter combination according to the target brain region, and regulating and controlling the brain stimulation instrument according to the stimulation parameter combination;
after the operation time of the brain stimulation instrument reaches a preset time, re-acquiring the global signal cooperativity;
judging whether brain stimulation is carried out on the target user according to the global signal cooperativity;
if brain stimulation is carried out, continuing to execute the step of acquiring the synchronicity of local signals corresponding to each brain region;
and if the brain stimulation is not performed, controlling the brain stimulation instrument to stop running.
In one implementation, the brain stimulation device is a transcranial alternating current stimulation device.
Based on the above embodiment, the present invention also provides a terminal, and a functional block diagram thereof may be shown in fig. 3. The terminal comprises a processor, a memory, a network interface and a display screen which are connected through a system bus. Wherein the processor of the terminal is adapted to provide computing and control capabilities. The memory of the terminal includes a nonvolatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of the operating system and computer programs in the non-volatile storage media. The network interface of the terminal is used for communicating with an external terminal through a network connection. The computer program is executed by a processor to implement a brain stimulation modulation method. The display screen of the terminal may be a liquid crystal display screen or an electronic ink display screen.
It will be appreciated by those skilled in the art that the functional block diagram shown in fig. 3 is merely a block diagram of some of the structures associated with the present inventive arrangements and is not limiting of the terminal to which the present inventive arrangements may be applied, and that a particular terminal may include more or less components than those shown, or may combine some of the components, or have a different arrangement of components.
In one implementation, the memory of the terminal has stored therein one or more programs, and the one or more programs configured to be executed by one or more processors include instructions for performing a brain stimulation modulation method.
Those skilled in the art will appreciate that implementing all or part of the above described methods may be accomplished by way of a computer program stored on a non-transitory computer readable storage medium, which when executed, may comprise the steps of the embodiments of the methods described above. Any reference to memory, storage, database, or other medium used in embodiments provided herein may include non-volatile and/or volatile memory. The nonvolatile memory can include Read Only Memory (ROM), programmable ROM (PROM), electrically Programmable ROM (EPROM), electrically Erasable Programmable ROM (EEPROM), or flash memory. Volatile memory can include Random Access Memory (RAM) or external cache memory. By way of illustration and not limitation, RAM is available in a variety of forms such as Static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double Data Rate SDRAM (DDRSDRAM), enhanced SDRAM (ESDRAM), synchronous Link DRAM (SLDRAM), memory bus direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM), among others.
In summary, the invention discloses a brain stimulation regulation device, a method, a terminal and a storage medium, wherein the device comprises: the global detection module is used for acquiring global signal cooperativity of a plurality of brain areas of a target user, wherein the global signal cooperativity is calculated based on first brain wave data acquired by each brain area; the global judging module is used for judging whether brain stimulation is carried out on the target user according to the global signal cooperativity; the local detection module is used for acquiring local signal synchronicity corresponding to each brain region if brain stimulation is carried out, wherein the local signal synchronicity of each brain region is calculated based on second brain wave data acquired by a plurality of sites in the brain region; and the brain region screening module is used for screening out a target brain region to be stimulated according to the local signal synchronism of each brain region, and regulating and controlling a brain stimulation instrument used by the target user according to the target brain region. According to the brain wave data analysis method and the brain wave data analysis device, the brain wave data of the user are analyzed together from the global level and the local level, so that objective and accurate regulation and control of a brain stimulation instrument can be realized. Solves the problems that the transcranial electric stimulation instrument in the prior art is usually regulated and controlled according to subjective judgment and experience guidance of professionals, and objective and accurate regulation and control are difficult to realize.
It is to be understood that the invention is not limited in its application to the examples described above, but is capable of modification and variation in light of the above teachings by those skilled in the art, and that all such modifications and variations are intended to be included within the scope of the appended claims.

Claims (10)

1. A brain stimulation modulation device, the device comprising:
the global detection module is used for acquiring global signal cooperativity of a plurality of brain areas of a target user, wherein the global signal cooperativity is calculated based on first brain wave data acquired by each brain area;
the global judging module is used for judging whether brain stimulation is carried out on the target user according to the global signal cooperativity;
the local detection module is used for acquiring local signal synchronicity corresponding to each brain region if brain stimulation is carried out, wherein the local signal synchronicity of each brain region is calculated based on second brain wave data acquired by a plurality of sites in the brain region;
and the brain region screening module is used for screening out a target brain region to be stimulated according to the local signal synchronism of each brain region, and regulating and controlling a brain stimulation instrument used by the target user according to the target brain region.
2. The brain stimulation modulation device of claim 1, wherein the global detection module comprises:
the brain region comparison unit is used for calculating signal cooperativity between every two brain regions according to the first brain wave data;
and the cooperativity calculation unit is used for calculating the global signal cooperativity according to each signal cooperativity.
3. The brain stimulation modulation device of claim 1, wherein the global judgment module comprises:
the threshold determining unit is used for acquiring the user information of the target user and determining a synergy threshold according to the user information;
the execution judging unit is used for performing brain stimulation if the global signal cooperativity is smaller than the cooperativity threshold value; if the global signal synergy is greater than or equal to the synergy threshold, no brain stimulation is performed.
4. The brain stimulation modulation device of claim 1, wherein the local detection module comprises:
the characteristic acquisition unit is used for acquiring oscillation characteristic data corresponding to each second brain wave data respectively;
a similarity calculation unit configured to calculate oscillation similarity of each of the second brain wave data based on each of the oscillation feature data;
and the synchronicity calculating unit is used for determining the synchronicity of the local signals according to the oscillation similarity.
5. The brain stimulation modulation device of claim 1, wherein the brain region screening module comprises:
and the synchronicity comparison unit is used for determining the target brain region according to the brain region with the minimum synchronicity of the local signals.
6. The brain stimulation modulation device of claim 1, wherein the brain region screening module further comprises:
the parameter determining unit is used for determining a stimulation parameter combination according to the target brain region and regulating and controlling the brain stimulation instrument according to the stimulation parameter combination;
the timing detection unit is used for acquiring the global signal cooperativity again after the operation time length of the brain stimulation instrument reaches the preset time length;
judging whether brain stimulation is carried out on the target user according to the global signal cooperativity;
if brain stimulation is carried out, continuing to execute the step of acquiring the synchronicity of local signals corresponding to each brain region;
and if the brain stimulation is not performed, controlling the brain stimulation instrument to stop running.
7. The brain stimulation control device according to claim 1, wherein the brain stimulation apparatus is a transcranial alternating current stimulation apparatus.
8. A method of brain stimulation modulation, the method comprising:
acquiring global signal cooperativity of a plurality of brain regions of a target user, wherein the global signal cooperativity is calculated based on first brain wave data acquired by each brain region;
judging whether brain stimulation is carried out on the target user according to the global signal cooperativity;
if brain stimulation is carried out, local signal synchronicity corresponding to each brain region is obtained, wherein the local signal synchronicity of each brain region is calculated based on second brain wave data acquired by a plurality of sites in the brain region;
and screening out a target brain region to be stimulated according to the local signal synchronism of each brain region, and regulating and controlling a brain stimulation instrument used by the target user according to the target brain region.
9. A terminal comprising a memory and one or more processors; the memory stores more than one program; the program comprising instructions for performing the brain stimulation modulation method of claim 8; the processor is configured to execute the program.
10. A computer readable storage medium having stored thereon a plurality of instructions adapted to be loaded and executed by a processor to implement the steps of the brain stimulation modulation method of claim 8.
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