CN1173647C - Refreshing beverage - Google Patents
Refreshing beverage Download PDFInfo
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- CN1173647C CN1173647C CNB01144410XA CN01144410A CN1173647C CN 1173647 C CN1173647 C CN 1173647C CN B01144410X A CNB01144410X A CN B01144410XA CN 01144410 A CN01144410 A CN 01144410A CN 1173647 C CN1173647 C CN 1173647C
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Abstract
The present invention provides a beverage which has the functions of refection and fatigue resistance. Every 3500 mg of beverage solids contain 300 to 450 mg of the magnesium salt of L-asparaginic acid, 50 to 125 mg of taurine and 30 to 45 mg of caffeine. The beverage can also contain one or a plurality of kinds of sugar and one or a plurality of vitamins. Preferably the form of the beverage provided by the present invention is effervescent tablets. Animal experiments prove that the beverage has obvious functions of refection and fatigue resistance, has the functions of promoting fat mobilization in a body, improving energy metabolism and strengthening the antioxidation function, and does not obviously affect the levels of the muscle glycogen and the liver glycogen of animals.
Description
Technical field:
The present invention relates to a kind of beverage, particularly a kind of pick-me-up that can play antifatigue effect.
Background technology:
Some researchs in recent years disclose after tired reason and high strength or the long working that energy i (in vivo) material such as minimizings such as glycogen, triglycerides and aliphatic acid and ATP, acidic materials are accumulated, free-radical generating increases and to remove factor such as minimizing relevant, therefore, supply by the nutrition attainment, improve free serum triglycerides and aliphatic acid level, the level of reduction serum lipid overoxidation product MDA and removing free radical etc. can promote body fat to mobilize, provide body movement required energy matter, effect, play antifatigue effect.
Existing anti-fatigue beverage such as red drink heavily material (red ox vitamin Beverage Company Limited produce) are the vitamin drinks, and its main antifatigue composition is vitamin, taurine, lysine, inositol, caffeine.
Summary of the invention:
The objective of the invention is to develop a kind of beverage with the antifatigue effect of refreshing oneself.
The invention provides a kind of beverage, contain following material in every 3500mg beverage solid content with the antifatigue effect of refreshing oneself:
L-asparatate magnesium salts 300～450mg,
Taurine 50～125mg,
Caffeine 30～45mg,
The preferable range of above-mentioned composition is:
L-asparatate magnesium salts 350～400mg,
Taurine 80～120mg,
Caffeine 35～42mg.
Can also contain one or more sugar in the pick-me-up of the present invention, the content range of sugar in every 3500mg beverage solid content is 500～2000mg; Described sugar can be Aspartame (Aspartame) compound sugar, sucrose or fructose.
Can also contain one or more vitamins in the pick-me-up of the present invention, as Cobastab
1, vitamin C and vitamin E, its content range in every 3500mg beverage solid content is: Cobastab
10.6～1.2mg, Catergen 0～60mg, vitamin E2～10mg.
The base-material of beverage of the present invention is to can be used as edible conventional beverage assistant agent, as comprising some carriers arbitrarily, comprises filler, diluent, wetting agent, granulating agent, lubricant, adhesive, disintegrant etc.Preferred filler comprises starch, glucose, sucrose, lactose, sweet mellow wine, calcium phosphate, calcium carbonate, cellulose.Preferred lubricant comprises talcum powder, CMS, polyvinylpyrrolidone (PVP) and silica gel, dolomol etc.Wetting agent comprises water, ethanol, syrup etc., and diluent comprises starch, glucose, lactose etc., and adhesive comprises dextrin, starch slurry, syrup etc., and disintegrant comprises starch, microcrystalline cellulose etc.Selected any composition and consumption depend on many factors, comprise the concentration of beverage formulations, functional component etc.In the scope that does not break away from essence of the present invention, those skilled in the art can design proper formula, comprises selecting composition and consumption arbitrarily.
In order to make solid beverage of the present invention easy to use, but need not to stir quick autolysis, easy to carry, the base-material of pick-me-up of the present invention can be the various base-materials that self-dissolving generates beverage that are suitable for.Beverage of the present invention can be a solid pharmaceutical preparation, as pulvis, granule or tablet, effervescent agent etc.; Also can be liquid beverage, as the aqueous solution, oral liquid etc.Preferably effervescent agent, most preferably effervescent tablet.
The effervesce base-material that the present invention selects for use comprises acid and base material, described acid comprises inorganic acid, organic acid and salt thereof commonly used in the various beverage industries, as phosphoric acid, hydrochloric acid, citric acid, tartaric acid, malic acid, fumaric acid, natrium citricum and ascorbic acid etc., preferred acid is citric acid, natrium citricum, in every 3500mg beverage solid content, the content range of acid is 800～2000mg, and preferred content is 1500mg; Described base material package is drawn together sodium carbonate and sodium acid carbonate etc., preferably sodium acid carbonate.In every 3500mg beverage solid content, the content range of alkali is 300～900mg, and preferred content is 700-800mg.
Effervescent tablet compressing tablet usual way is, the Powdered functional materials that will have suitable particle size is scattered in the auxiliary material of compatibility with it, as the diluent of wetting agent, non-activity, dispersant, carrier adhesive, lubricant etc., the batching compressing tablet that will mix then with a kind of suitable machine.
In order to improve the sense organs such as color, smell and taste of beverage, can add one or more fragrant agent and colouring agent, preferably natural essence and natural colouring matters of hiding of various this areas routine.
Pick-me-up production technology of the present invention is:
1, the technological process of production:
Ingredient inspection → pulverizing → batching → mixing → system softwood → granulation → oven dry → cooling → whole grain → compressing tablet → packing.
2, key points for operation:
(1) ingredient inspection: the raw material that uses in producing is tested by the related request of stipulating in the national standard.
(2) raw material pulverizing: raw material before batching that granularity is big is pulverized in advance, is sieved, and mixes in process to guarantee color and luster homogeneous and raw material, and it is stable to ensure the quality of products.
(3) batching, mixing: adopt equivalent to increase progressively mixing method step by step primary raw material is mixed in proportion.
(4) system softwood: spray wetting agent and adhesive on mixed material.
(5) granulation: with the softwood granulation on granulator that makes.
(6) drying: wet granular is dried.
(7) whole grain: the whole grain that sieves makes dried material particles degree even.
(8) compressing tablet: compressing tablet after in the good material of drying, adding disintegrant, lubricant.
(9) packing: pack.
Beverage provided by the invention has been carried out the biological test of following security and functional assays:
Horn method by the GB defined has carried out animal acute toxicity test, proves the good (LD of security
50＞9260mg/kg).
Through the depleted test of animal swimming, prove and compare, the depleted time of beverage treated animal swimming significantly is longer than control animals, illustrates that this pick-me-up has the obvious anti-fatigue effect.
Suspend the test group animal in midair swimming after 6 hours in 37 ℃ of water, carry out spacious behavior determination, beverage treated animal brain function state obviously is better than control animals, illustrates that pick-me-up has the effect of significantly refreshing oneself.
Through mensuration, prove that pick-me-up has the effect that the promotion body fat was mobilized, improved energetic supersession, strengthens anti-oxidation function to test group animal and the multiple biochemical indicator of control animals.And the level of animal inose unit, liver glycogen is not made significant difference.Refresh oneself, the mechanism of action of antifatigue with promote body fat to mobilize, improve energetic supersession, to strengthen anti-oxidation function relevant
The specific embodiment:
Embodiment 1～10
Beverage formula (unit: mg)
| Embodiment | L-asparatate magnesium salts | Taurine | Caffeine | Aspartame | Compound sugar | Fructose | Vitamin B1 | Vitamin C | Vitamin E | The effervesce base-material * | Other auxiliary material ** |
| 1 | 375 | 100 | 38 | 300 | 500 | - | 1 | 50 | 3 | Add to 3500 | - |
| 2 | 300 | 125 | 30 | 500 | 500 | - | 1 | 50 | 3 | Add to 3500 | - |
| 3 | 400 | 100 | 40 | 300 | - | 400 | 1.2 | 60 | 2 | Add to 3500 | - |
| 4 | 375 | 100 | 38 | - | 500 | - | 0.6 | - | - | Add to 3500 | - |
| 5 | 450 | 50 | 45 | - | - | - | - | - | - | Add to 3500 | - |
| 6 | 400 | 100 | 40 | 400 | - | 500 | - | 20 | - | Add to 3500 | - |
| 7 | 375 | 100 | 38 | 300 | 500 | - | 1 | 50 | 3 | - | 1 adds to 3500 |
| 8 | 400 | 100 | 40 | 300 | - | - | 1 | 60 | 6 | - | 1 adds to 3500 |
| 9 | 400 | 80 | 35 | - | - | - | - | - | 8 | - | 2 add to 3500 |
| 10 | 450 | 125 | 38 | - | - | - | 1 | 30 | 10 | - | 2 add to 3500 |
*Effervesce base-material: citric acid: natrium citricum: sodium acid carbonate: essence: pigment=30: 1: 15: 4: 0.1
*Other auxiliary material: 1 sucrose: dextrin: flavoring orange essence: pigment=2000: 400: 800: 1
2 sucrose: dextrin: flavoring orange essence: pigment=4000: 400: 600: 1
Embodiment 11 pick-me-ups (effervescent tablet) production technology
One, raw and auxiliary material requires:
1, citric acid: water white transparency crystallization or white particle, odorless has the strong acid flavor, relative density 1.655, citric acid content 〉=99.5%, other indexs meet regulation requirement among the GB1987-86.
2, vitamin C: water white transparency crystallization or white particle powder, odorless, flavor are salty, refrigerant sense are arranged, relative density 1.980, dry back content 99.0%, loss on drying 3.0～6.0%.
3, compound sugar: ash content≤0.1%, other indexs meet regulation requirement among the GB317.
4, Aspartame: white crystalline powder, odorless has intense sweetness, sweet taste threshold value 0.001～0.007%, pH4.5～5.5, loss on drying≤4.0%, ignition residue≤0.2%.
5, sodium acid carbonate: white powder, odorless, other indexs meet the requirement of GB-1887-90 regulation.
6, vitamin A: meet regulation requirement among the GB14750-93.
7, Cobastab
1: meet regulation requirement among the GB14751-93.
8, Cobastab
2: meet regulation requirement among the GB14752-93.
9, Cobastab
6: meet regulation requirement among the GB14753-93.
10, vitamin C: meet regulation requirement among the GB14754-93.
11, vitamin D: meet regulation requirement among the GB14755-93.
12, vitamin E: meet regulation requirement among the GB14756-93.
13, natural essence: meet regulation requirement among the GB-2760-1996.
14, pigment: meet regulation requirement among the GB-2760-1996.
Two, prescription: with embodiment 1 prescription
Three, the technological process of production and key points for operation:
1, technological process of production figure:
Ingredient inspection → pulverizing → batching → mixing → system softwood → granulation → oven dry → cooling → whole grain → compressing tablet → packing.
2, key points for operation:
(1) ingredient inspection: the raw material that uses in producing is tested by the related request of stipulating in the national standard.
(2) raw material pulverizing: before batching that granularity is big raw material such as citric acid, white granulated sugar etc. are pulverized on pulverizer in advance, and mistake 100 mesh sieves, to guarantee aesthetic in appearance, the color and luster homogeneous of tablet, raw material is mixed in process, thereby guarantee the quality stability of tablet.
(3) batching, mixing: pour primary raw material into mixer in proportion, start agitator raw material is mixed.For guaranteeing the abundant mixing of each raw material in the tablet, trace in the batching or minor constituent adopt equivalent to increase progressively mixing method step by step with mixing of primary raw material.
(4) system softwood: a little ethanol of spray on mixed material, back spray adhesive dextrin on compound finishes.
(5) granulation: the softwood that makes is caused 14 purpose particles on granulator, the particle of making places square pallet stand-by.
(6) drying: the wet granular in the square pallet is placed 70 ℃ of oven dry taking-ups after 1 hour down, in dry environment cooling down.
(7) whole grain: make dried material particles degree even through the whole grain that sieves, make in dry run, to stick to each other the caking part evenly, to be suitable for the compressing tablet requirement.
(8) compressing tablet: be dosed into tablet press machine after the good mixing of materials of drying is even, material is struck out circular piece, compressing tablet pressure is 4.5 * 10
3Kgf.
(9) packing: with certified tablet monolithic sealing packing on packing machine that type is complete.
Four, end product quality specification:
1, color and luster: white, uniformity.
2, form: round sheet, diameter 25mm, weigh 3.0 ± 0.2g, the sheet type is complete.
3, fragrance and flavour: sour and sweet palatability, different cultivars have its distinctive fruit aroma and flavour, free from extraneous odour.
4, impurity: the visible exogenous impurity of no naked eyes.
5, heavy metal index: plumbous (in Cu)≤1.0mg/kg, arsenic (in As)≤0.5mg/kg, copper (in Cu)≤10.0mg/kg.
6, microbiological indicator: total number of bacteria≤1000/g, coliform≤30/100g, pathogenic bacteria must not detect.
7, packaging material and specification: packaging material are the PET/AL/PE complex pocket, and specification is 50 * 55mm
2
8, sealing-strength: sealing-strength is not less than 3.4kgf/20mm.
9, the shelf-life: preserve at normal temperatures and never degenerated in 2 years.
Embodiment 12 voltinism matter are measured
1. the general proterties of beverage
The medicine materical crude slice of embodiment 1 drops into post-foaming dissolving in the water, and the beverage after the dissolving is orange colour, orange fragrance is arranged, sweet mouthfeel.Beverage pH is 4.2; The osmotic pressure of beverage is 125mosm/kgH behind 250ml dissolved in distilled water a slice medicine materical crude slice
2O dissolves that the osmotic pressure of beverage is 245mosm/kgH behind two medicine materical crude slice
2O.
2. active constituent content
After a slice medicine materical crude slice was dissolved in 250ml distilled water, various effective constituent determinations the results are shown in following table
The composition measurement result
Component content (mg/250ml)
Total reducing sugar 470.0
Asparatate 170.0
Taurine 82.50
Caffeine 53.43
Vitamin C 36.50
Cobastab
10.45
Vitamin E 2.30
Embodiment 13 acute toxicity tests
1. subjects
The effervescent beverage(s) of refreshing oneself, it is filled a prescription shown in embodiment 1.After every 3500mg was dissolved in 250ml distilled water, the pH that measures beverage by relevant National Standard Method respectively (adopted pHep
The HI98107pH instrumentation is fixed), the content (adopting mensuration such as titration, colorimetric method, automatic amino acid analyzer method, high-efficient liquid phase technique respectively) of osmotic pressure (adopting the FM-3A osmometer to measure) and relevant composition.
2. experimental animal and test method
Healthy male mice in kunming is provided by Inst. of Military Equipment, General Logistics Dept. of PLA, and mouse is raised in plastic casing, 6 in every box; Rat single head in the stainless steel metabolic cage is raised, and routine is freely drunk water, diet.Observe before the animal experiment and adapt to 5 days, check and begin to enter formal test after qualified, press the National Standard Method defined horn method (State Standard of the People's Republic of China: acute toxicity test, GB15193.3-94) carry out.
2. result of the test
Trial test: in 415-5120mg/kg body weight dosage range, after the animal filling stomach beverage (each 5, every 0.4ml), except excited reaction occurring, death condition do not occur.
Formal test: with 20 body weight is that the mouse of 19.8 ± 0.7 grams are divided into 2151,4640,10000, four dosage groups of 21500mg/kg, excited reaction appears in animal after irritating the stomach beverage, especially high dose group shows as in cage and scoots about, phenomenon such as have a fist fight mutually, the maximum dose level treated animal is dead 3 in 6 hours, 1 of inferior high dose group animal dead continues to observe a week, does not find other obvious abnormal response, the toxicity that this beverage is described between reality is nontoxic and nontoxic, LD
50＞9260mg/kg.See the following form
Animal dead situation in one week of acute toxicity test
Dosage death
(mg/kg) (head)
2151 0/5
4640 0/5
10000 1/5
21500 3/5
Embodiment 14 refreshes oneself and anti-fatigue effect is tested
All tests are undertaken by health supervision department of Ministry of Health of the People's Republic of China " the health food function assessment assessment process and the method for inspection, 1996 ".
One, open field test
1. subjects
The effervescent beverage(s) of refreshing oneself, it is filled a prescription shown in embodiment 1.
2. experimental animal and test method
Experimental animal is healthy male Wistar rat.
Adopt pharmacological testing method (Xu Shuyun: pharmacological testing method, second edition, the People's Health Publisher, 1994), process is as follows: animal spends the night on an empty stomach, be divided into drinking-water group and beverage group at random, (a kind of new swimming method sees that Xiao Jin rises etc.: rat suspension type swimming application study in exercise test in suspention swimming in 37 ℃ of water.China's applied physiology magazine, 1997,13 (supplementary issues): 46) 6 hours, irritated stomach 3 times in 2,4,6 hours respectively at swimming beginning back, each every 2ml, control group is irritated distilled water, and test group is irritated beverage.Swimming finishes the back and adopts spacious case to carry out spacious behavior determination, with the influence of reflection beverage to the brain function state.
3. result of the test
Animal was suspended swimming in midair after 6 hours in 37 ℃ of water, carry out spacious behavior determination, from central square stop and walk lattice count the two indexes result as can be seen beverage treated animal brain function state obviously be better than the treated animal of drinking water, illustrate to be tried out and expects to have the effect of significantly refreshing oneself.See the following form
Pick-me-up is to the influence of spacious the behavior in animal swimming back
The upright number of times of lattice number is walked in group n body weight (gram) central square stop (second)
Drinking-water organizes 8 228.5 ± 8.9 28 ± 7 14 ± 11 4 ± 3
Beverage group 8 226.9 ± 7.6 19 ± 9*, 33 ± 25* 5 ± 4
Statistical analysis: * P＜0.05, the central square dwell data adopts the t check analysis, walks the lattice logarithmic data and adopts the rank test analysis.
Two. the depleted test of swimming
1. subjects
Pick-me-up, it is filled a prescription shown in embodiment 9.
2. experimental animal and test method
Experimental animal is healthy male Wistar rat.
Test method:
Before the formal test, animal carries out swimming instruction 2 times at least, trains 30 minutes at every turn; During formal test, in 37 ℃ of water, suspend swimming in midair after animal spends the night on an empty stomach, during the swimming, irritated stomach once every 2 hours, each every 2ml, control group is irritated distilled water, and test group is irritated beverage.
After the animal swimming fatigue, head does not have in the entry, with occur three times, each more than 5 seconds the person serve as that swimming is depleted;
3. result of the test
Adopt t check analysis (* * P＜0.01), beverage treated animal swimming depleted average time is 14.1 hours, significantly is longer than drinking-water treated animal (13.0 hours), illustrate to be tried out and expects to have the obvious anti-fatigue effect.
Three. the swimming metabolic test
1. subjects
Pick-me-up, it is filled a prescription shown in embodiment 2.
2. experimental animal and test method
Experimental animal is healthy male Wistar rat.
The swimming metabolic test in order to the reflection beverage to the influence of exercise metabolism in the animal body, i.e. the beverage biochemical mechanism of antifatigue effect of refreshing oneself.Before the animal swimming and after swimming six hours, take eye socket blood respectively, muscle and liver sample adopt automatic clinical chemistry analyzer (Cobas Mira 31-0052 type) and Nanjing to build up method such as bio-engineering research institute kit and measure blood sugar respectively, lactic acid, triglycerides, blood free fatty (trip resin acid), albumin, urea nitrogen (BUN), MDA (MDA), superoxide dismutase (SOD), glutathione peroxidase (GSHPx), lactic dehydrogenase (LDH), creatine kinase (CK), glutamic-oxalacetic transaminease (GOT), glutamic-pyruvic transaminase (GPT), inose unit and liver glycogen index.
3. result of the test
Swim the every index of preceding two treated animals (comprising the heart, liver, renal function index) all in normal range (NR); Swimming back drinking-water treated animal blood sugar, albumin, triglyceride concentration significantly descend, and lactic acid, BUN, MDA, CK, GOT, GPT, LDH level raise, and animal movement metabolism acceleration is described, freely produce increase; But, beverage treated animal swimming back blood triglyceride, trip resin acid concentration are significantly higher than the drinking-water treated animal, and the MDA level significantly is lower than the drinking-water treated animal, in addition, the beverage treated animal is swum, and back SOD is active to have remarkable rising before the swimming, illustrates that pick-me-up has the effect that the promotion body fat was mobilized, improved energetic supersession, strengthens anti-oxidation function.Pick-me-up does not make significant difference to the level of necton inose unit, liver glycogen.
Tried out the regulating action of material to the animal movement metabolism
After swimming before the swimming
Project n
Drinking-water group beverage group drinking-water group beverage group
Blood sugar (mol/L) 8 6.02 ± 0.72 6.69 ± 1.64 2.97 ± 0.56 * * 2.74 ± 0.56 * *
Albumin (g/L) 8 40.5 ± 1.0 41.5 ± 1.2 37.6 ± 1.3 * * 37.5 ± 1.9 * *
Triglycerides (mmol/L) 8 1.16 ± 0.29 0.92 ± 0.29 0.26 ± 0.06 * * 0.42 ± 0.08 * * * *
Trip resin acid (umol/L) 8 553.2 ± 168.4 604.1 ± 135.8 551.4 ± 108.3 772.3 ± 149.5**
Lactic acid (mg/L) 8 655.7 ± 153.6 651.4 ± 130.9 1003.8 ± 229.5 * * 1136.3 ± 323.9 * *
BUN(mmol/L) 8 4.92±0.67 4.63±0.57 8.51±1.44×× 9.05±1.59××
MDA(mmol/L) 8 8.2±0.5 7.6±0.7 9.8±1.8× 7.6±0.6**
CK(U/L) 8 793.5±111.9 791.5±240.4 2557.0±1033.2×× 2806.5±611.1××
GOT(U/L) 8 151.8±17.1 150.0±26.1 324.5±63.3×× 348.1±50.6××
GPT(U/L) 8 52.0±7.9 51.6±4.3 98.8±16.9×× 115.9±26.9××
GSHPx(AU) 8 154.8±10.6 148.9±7.8 135.8±8.3× 140.2±9.5
LDH(U/L) 8 518.9±153.5 569.3±204.3 1240.9±456.9×× 1187.5±277.5××
SOD(NU/ml) 8 166.7±18.4 150.2±28.5 165.5±22.2 172.4±15.5×
Statistical analysis: * P＜0.05, * * P＜0.01, the drinking-water group is compared with the beverage group; * P＜0.05, * * P＜0.01, compare before and after the swimming.
Adopt the t check analysis.
Claims (5)
1, a kind of beverage with the antifatigue effect of refreshing oneself, contain following material in every 3500mg beverage solid content:
L-asparatate magnesium salts 300～450mg
Taurine 50～125mg
Caffeine 30～45mg.
2, beverage as claimed in claim 1, the preferable range of contained material is in every 3500mg beverage solid content:
L-asparatate magnesium salts 350～400mg
Taurine 80～120mg
Caffeine 35～42mg.
3, beverage as claimed in claim 1 also contains one or more vitamins, and described vitamin comprises vitamin B1, vitamin C and vitamin E, and the content range in every 3500mg beverage solid content is: Cobastab
10.6～1.2mg, vitamin C 20～60mg, and vitamin E 2～10mg.
4, a kind of effervescent tablet contains acid and base material, it is characterized in that: contain following material in every 3500mg solid content:
L-asparatate magnesium salts 300～450mg
Taurine 50～125mg
Caffeine 30～45mg.
5, effervescent tablet as claimed in claim 4 also contains one or more vitamins, and described vitamin comprises vitamin B1, vitamin C and vitamin E, and the content range in every 3500mg solid content is: Cobastab
10.6～1.2mg, vitamin C 20～60mg, and vitamin E 2～10mg.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB01144410XA CN1173647C (en) | 2001-12-17 | 2001-12-17 | Refreshing beverage |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB01144410XA CN1173647C (en) | 2001-12-17 | 2001-12-17 | Refreshing beverage |
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|---|---|
| CN1426703A CN1426703A (en) | 2003-07-02 |
| CN1173647C true CN1173647C (en) | 2004-11-03 |
Family
ID=4677558
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|---|---|---|---|
| CNB01144410XA Expired - Fee Related CN1173647C (en) | 2001-12-17 | 2001-12-17 | Refreshing beverage |
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Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100360139C (en) * | 2005-11-25 | 2008-01-09 | 浙江省医学科学院 | Lead-removing growth-assisting tablet and its preparing method |
| PT2214521T (en) * | 2007-11-16 | 2019-03-29 | Int Ip Holdings Llc | Edible energy composition with low caffeine |
| ES2362138B1 (en) * | 2009-07-03 | 2012-01-26 | Piero Cattarini Esteban | ENERGY DRINK POWDER |
| CN105412041A (en) * | 2012-08-02 | 2016-03-23 | 佳格食品股份有限公司 | Effervescent tablet with energizing enhancing effect |
| CN102940297A (en) * | 2012-12-10 | 2013-02-27 | 商晓华 | Brain refreshing and fitting beverage |
| CN104489849B (en) * | 2015-01-09 | 2017-01-04 | 精晶药业股份有限公司 | A kind of solid beverage containing vitamin regulator |
| CN104686668B (en) * | 2015-03-24 | 2018-02-09 | 姚国友 | A kind of vegetable protein health breast bamboo shoot and preparation method thereof |
| CN104855658A (en) * | 2015-05-31 | 2015-08-26 | 威海贯标信息科技有限公司 | Orally disintegrating tablet capable of restoring consciousness and refreshing |
| CN107927245A (en) * | 2017-11-30 | 2018-04-20 | 重庆藏天露生物科技有限公司 | A kind of functional solid beverage and its preparation process for improving anoxia endurance |
-
2001
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