CN117357332A - Tension ring for preventing post-failure - Google Patents
Tension ring for preventing post-failure Download PDFInfo
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- CN117357332A CN117357332A CN202311608264.0A CN202311608264A CN117357332A CN 117357332 A CN117357332 A CN 117357332A CN 202311608264 A CN202311608264 A CN 202311608264A CN 117357332 A CN117357332 A CN 117357332A
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- ring
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- outer body
- elastic
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
Abstract
The utility model provides a tension ring of prevention back obstacle, includes elastic ring inner core and ring outer body, ring outer body parcel elastic ring inner core, ring outer body material is hydrophobic acrylic ester, elastic ring inner core has the opening with ring outer body the annular inboard of elastic ring inner core is provided with draws closes the loop structure, should draw closes the loop structure and pass ring outer body, is located ring outer body annular inboard, the opening both ends of ring outer body are provided with the buckling parts of mutually supporting respectively, the ring outer body after the buckling closely laminates with lens bag equatorial portion under the elastic tension effect of elastic ring inner core. According to the invention, the hydrophobic acrylic acid material is combined with the elastic ring inner core with elastic tension, so that the hydrophobic acrylic acid is tightly adhered with the posterior capsule, thereby preventing repeated posterior obstacle, and achieving the effect of effectively inhibiting division, proliferation and migration of epithelial cells for a long time.
Description
Technical Field
The invention relates to the technical field of eye surgery, in particular to a tension ring for preventing post-cataract.
Background
Cataract is a common blinding eye disease, and secondary cataract (posterior capsular opacification, PCO) is a common complication after cataract surgery, and secondary cataract refers to white turbidity formed on a posterior capsule after cataract surgery due to migration, proliferation and differentiation of residual lens epithelial cells or cortex along the posterior capsule, is a common cause of visual deterioration after cataract surgery, and can occur for weeks to years after cataract surgery. For adult PCO, a Nd-YAG laser is used for cutting the back capsule, and for patients who do not match with the Nd-YAG laser and are unsuitable, an operation is used for cutting the back capsule. YAG laser cutting of the posterior capsule, although an effective treatment, involves invasive surgery and presents additional risks to the patient, including complications such as intraocular lens injury, changes in the effective position of the intraocular lens, even dislocation, elevated intraocular pressure, macular capsulorhexis, and increased incidence of retinal detachment, although there are many PCO patients for whom YAG laser is not available:
1. for infants, children and people who cannot cooperate with the operation, in order to reduce the incidence rate of PCO for the infants and children, a posterior capsule resection combined anterior segment vitrectomy with more complex operation and higher risk is often needed to be adopted in cataract surgery;
2. YAG laser treatment cannot be performed on patients with severe corneal nebula and small pupils which cannot be dispersed;
3. for mild PCO patients with visual function, YAG laser is difficult to position, so that the intraocular lens is easy to damage, PCO is often required to be further developed for treatment, and the YAG laser has great influence on the functions of various refractive intraocular lenses such as multifocal intraocular lenses, continuous vision intraocular lenses, astigmatism correction intraocular lenses and the like in refractive cataract surgery.
For prevention of PCO, the current solution ideas include two aspects, one, biochemical methods, numerous literature reports have been made at home and abroad, various drugs and formulations have been explored to eliminate residual lens epithelial cells in the capsular bag, including targeting mechanisms and methods of administration in human and preclinical PCO animal models for different processes occurring in PCO, including antiproliferation, antimetation, antiadhesion and antimetabolite, and the like, li X, liang C, yan H et al in the journal of pharmaceutical technology (Clinical Translation of Long-Acting Drug Delivery Systems for Posterior Capsule Opacification prophyllis.2023 apr 13; 15-4:1235.) have been summarized and reported as antimetabolites, distilled water, aldose reductase inhibitors, and the like, based on two general criteria: (1) evaluating the efficacy of the drug in vivo; (2) providing a drug dose. Experimental studies have shown that these drugs, particularly chemotherapeutic drugs, are effective against proliferation and fibrosis of lens epithelial cells, but have hampered clinical use of such drugs against damage to normal ocular tissues such as cornea, iris, zonules, etc. In order to reduce toxic side effects of drugs, nanotechnology has been used for drug delivery, and can be classified into the following types according to the preparation process: (1) The drug-loaded nano-carrier is coated on the intraocular lens; (2) deposition of the drug directly onto the intraocular lens; (3) Other dosage forms, including Nanoparticles (NPs), implants and hydrogel composites, however, the long-term safety and effectiveness of these improved methods remain to be validated for further animal and clinical trials. Secondly, according to the theory of NO SPACE, NO CELL, the physical blocking method mainly eliminates the proliferation and migration SPACE and channel of lens epithelial cells by improving the material and the form of the intraocular lens, and the method is safe and has NO toxic or side effect, thus having good research and development and application prospects in clinic at present.
In the prior art, chinese patent document with application number of CN200810026557.7 discloses an intraocular implant for preventing and treating occurrence of lens posterior capsule turbidity (posterior obstacle), a preparation method thereof and application of docetaxel in preparing medicaments for preventing and treating lens posterior capsule turbidity, wherein the implant comprises docetaxel and at least one polymer carrier, and the content of docetaxel in the preparation is 0.01-20%; the ratio of the polymer carrier to the medicine is 5:1-10000:1. The preparation method comprises the following steps: uniformly mixing docetaxel and polymer carrier monomer according to a certain proportion, adding animal starting agent and/or cross-linking agent, introducing nitrogen gas for protection, making reaction in mould at 50-100 deg.C until forming and sterilizing. The scheme adopts the medicine and the polymer carrier to prepare the implant in the capsular bag, and the implant is implanted into the cavity of the capsular bag of the crystalline lens after the extracapsular cataract extraction operation, thereby playing a role in inhibiting the lens epithelial proliferation for a long time. The method for externally applying the medicine needs to repeatedly pour the medicine to achieve an ideal inhibition effect so as to avoid the problem of recurrence, but repeatedly pouring the medicine can cause repeated damage to the eye to prevent the eye from causing the risk of intraocular infection, and the medicine inevitably has other concurrent harm, such as anaphylactic reaction, inhibition of other normal cell growth and the like.
Materials commonly used for intraocular lenses include hydrophobic acrylates, hydrophilic acrylates, polymethyl methacrylates, and the like, wherein the hydrophobic acrylates tend to adhere to the capsular bag of the lens, reduce cell proliferation and migration, and are effective in reducing the incidence of posterior obstacle as compared to other materials, such as those reported by Vasavada et al in J Journal of cataract and refractive surgery (2011: 1050-9.) "Comparison of posterior capsule opacification with hydrophobic acrylic and hydrophilic acrylic intraocular lens," Zhao Y et al in J Medicine (Baltimore) (2017 nov; 96-44.). Comparison of hydrophobic and hydrophilic intraocular lens in preventing posterior capsule opacification after cataract surgery: an updated meta-analysis, all demonstrate that intraocular lenses employing hydrophobic acrylic materials have significantly reduced posterior capsular opacification and are effective in inhibiting posterior obstacle. The use of a full peripheral design for the intraocular lens also reduces the incidence of post-amblyopia, as reported by Maedel et al, "Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract surgery," The Cochrane database of systematic reviews vol.8,8cd 01516.16 aug.2021, has demonstrated the effectiveness of this improved design. However, even though PCO is reduced by the hydrophobic acrylic acid ester intraocular lens designed with a square edge of 360 degrees, it is only 5 years that even for adults, the incidence of childhood is certainly much higher than that of the adult, and the incidence of adults is increased with the extension of time, because the intraocular lens itself has no backward and peripheral tension, gaps are still easily generated between the intraocular lens and the capsular bag, and migration and proliferation of epithelial cells are difficult to be prevented.
Disclosure of Invention
In order to solve the problem that the vision is reduced due to the fact that the existing ophthalmic cataract is easy to suffer from after-cataract surgery, the invention provides the tension ring for preventing the after-cataract, the adopted hydrophobic acrylic ester material is easy to adhere to the capsular bag, polymethyl methacrylate (PMMA) has elastic tension and is harmless, the hydrophobic acrylic ester tension ring is tightly attached to the equatorial part of the lens capsular bag under the pushing and pressing of the tension of the cohesive methyl methacrylate, the formation of gaps is avoided, the space for proliferation and migration of epithelial cells is thoroughly eliminated, and the after-cataract is effectively prevented.
The specific technical scheme is as follows:
the utility model provides a tension ring of prevention back obstacle, includes elastic ring inner core and ring outer body, ring outer body parcel elastic ring inner core, ring outer body material is hydrophobic acrylic ester, elastic ring inner core has the opening with ring outer body the annular inboard of elastic ring inner core is provided with draws closes the loop structure, should draw closes the loop structure and pass ring outer body, is located ring outer body annular inboard, the opening both ends of ring outer body are provided with the buckling parts of mutually supporting respectively, the ring outer body after the buckling closely laminates with lens bag equatorial portion under the elastic tension effect of elastic ring inner core.
As an optimization: the section of the ring outer body is square.
As an optimization: the pull tab structure comprises a first pull tab and a second pull tab, and the first pull tab and the second pull tab are connected to the elastic ring inner core.
As an optimization: the first pull tab is connected to the end part of the inner core of the elastic ring, the second pull tab is connected to the annular middle part of the inner core of the elastic ring, and the first pull tab and the second pull tab are arranged opposite to each other.
As an optimization: the first pull-close loop comprises a connecting graft and a circular ring, one end of the connecting branch is connected with the end part of the elastic ring inner core, and the other end of the connecting branch is connected with the circular ring.
As an optimization: the connecting branch is provided with a drag hook part, and the connecting branch is connected with the circular ring through the drag hook part.
As an optimization: the two annular opening ends of the ring outer body are respectively provided with an inner concave plate body and an outer concave plate body, the inner concave plate body and the outer concave plate body are respectively and uniformly provided with inner ratchets and outer ratchets, and the inner ratchets are matched with the outer ratchets.
As an optimization: the annular outer body is provided with an inner concave plate body and an outer concave plate body respectively at two annular opening ends, grooves and protruding blocks are uniformly arranged on the inner concave plate body and the outer concave plate body, and the grooves are matched with the protruding blocks.
The beneficial effects of the invention are as follows: the hydrophobic acrylic acid ester material can adhere to the lens capsular bag to prevent the migration and proliferation of lens epithelial cells, but the hydrophobic acrylic acid ester material is free of tension, easy to form a gap with the lens capsular bag to prevent adhesion, and PMMA material has stronger elasticity, and is combined with the hydrophobic acrylic acid ester material, a PMMA ring inner core with an opening part in a C shape is arranged in the hydrophobic acrylic acid ester ring to increase the extrusion force of the hydrophobic acrylic acid ester ring to the equatorial part of the capsular bag, so that the gap between the hydrophobic acrylic acid ester and the capsular bag can be eliminated, adhesion between the hydrophobic acrylic acid ester and the capsular bag is accelerated and ensured, and the hydrophobic acrylic acid ester material and the capsular bag are matched by utilizing the buckling part to form a complete circular ring, so that dead angle-free outward extrusion is realized, the migration and proliferation space of the epithelial cells is eliminated, and the occurrence of subsequent obstacle is prevented.
Drawings
FIG. 1 is a schematic cross-sectional view of the whole of the first embodiment of the present invention.
FIG. 2 is a schematic structural view of the exosome in the first form of the present invention.
FIG. 3 is a schematic view of the structure of the first form of the present invention after chamfering the outer ring body.
FIG. 4 is a schematic structural view of the exosome in the second embodiment of the present invention.
FIG. 5 is a schematic cross-sectional view of the third embodiment of the present invention.
In the figure: an elastic ring inner core 1; an outer ring body 2; a pull-on tab construction 3;
a first pull tab 31; a second pull tab 32; grafting 33; a circular ring 34; a hook portion 35;
a concave plate body 21; an outer concave plate 22; an inner ratchet 23; an outer ratchet 24; a groove 25; bumps 26.
Detailed Description
The preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings so that the advantages and features of the present invention can be more easily understood by those skilled in the art, thereby making clear and defining the scope of the present invention.
As shown in fig. 1 to 5: a tension ring for preventing posterior obstacle is provided with an elastic ring inner core 1 and an outer ring body 2, wherein the outer ring body 2 wraps the elastic ring inner core 1, the outer ring body 2 is made of hydrophobic acrylic ester, the elastic ring inner core 1 and the outer ring body 2 are provided with opening parts, the annular inner side of the elastic ring inner core 1 is provided with a pull-in tab structure 3, the pull-in tab structure 3 penetrates through the outer ring body 2 and is positioned on the annular inner side of the outer ring body 2, two ends of the opening part of the outer ring body 2 are respectively provided with a buckling part matched with each other, and the buckled outer ring body 2 is tightly attached to the equatorial part of a lens bag under the pushing and pressing action of the elastic tension of the elastic ring inner core 1.
The cross section of the ring outer body 2 is square, including rectangle and square and the shape similar to rectangle and square, the acrylic ester with high hydrophobicity is manufactured into a square ring with the length, width and height of 0.4-1.0mm and an opening, as shown in figure 3, in order to avoid causing discomfort to patients, the square edges and corners are rounded, but the hydrophobic acrylic ester is in a soft form and generally does not need to be processed.
The elastic ring inner core 1 is made of PMMA (polymethyl methacrylate) material with the radial direction of 0.15-0.20mm, has certain elastic tension, and hydrophobic acrylic ester is made of soft material, does not have the property, and can be tightly adhered to a posterior capsule by virtue of the outward tension of the elastic ring inner core 1 and the shape of the ring outer body 2, so that the division, proliferation and migration of epithelial cells can be well inhibited, and the elastic ring inner core is effective for a long time.
In addition, the cross section of the elastic ring inner core 1 is in a non-circular shape such as a D shape, a square shape or a circular shape, so that relative rotational displacement between the circular elastic ring inner core 1 and the outer wrapping ring body 2 is avoided, inconvenience in use is avoided, and when the circular elastic ring inner core 1 is actually used for a pull-in loop structure 3 with an annular inner side, the probability of relative rotational displacement is small, but local torsion is also avoided as much as possible.
The above-mentioned pull tab structure 3 includes a first pull tab 31 and a second pull tab 32, and may be provided with a plurality of pull tabs, but generally not necessarily, because the space position is small, two pull tabs are provided to satisfy the use requirement, wherein the first pull tab 31 is connected to the end position of the elastic ring inner core 1, the second pull tab 32 is connected to the annular middle position of the elastic ring inner core 1, the first pull tab 31 is opposite to the second pull tab 32, and the first pull tab 31 and the second pull tab 32 may be connected to other positions of the elastic ring inner core 1, but the pull difficulty may be increased.
The first pull tab 31 comprises a connecting graft 33 and a circular ring 34, one end of the connecting graft 33 is connected to the end part of the elastic ring inner core 1, the other end of the connecting graft 33 is connected with the circular ring 34, the second pull tab 32 has the same structure as the first pull tab 31, and the first pull tab 31 and the second pull tab 32 are pulled and closed through the circular ring 34.
Further, as shown in fig. 4, the linking and grafting part 33 has a hook part 35, the linking and grafting part 33 is connected with the circular ring 34 through the hook part 35, the second pull tab 32 has the same structure as the first pull tab 31, the first pull tab 31 and the second pull tab 32 can be pulled and closed more conveniently through the hook part 35, and the circular ring 34 can be used for passing the suture.
In order to facilitate the placement of the tension ring in the operation, the whole tension ring is usually in an opening shape, so that the elastic ring inner core 1 and the ring outer body 2 are both provided with openings, are in an opening shape, and are not easy to accurately place in the operation; therefore, the elastic ring inner core 1 is pulled by the pull-close loop structure 3 to enable the buckling parts of the ring outer body 2 to be matched together, so that a complete ring shape is formed, the division, proliferation and migration of epithelial cells can be prevented and prevented without dead angles, adhesion between the elastic ring inner core and the elastic ring inner core is accelerated and ensured, the space for migration of the epithelial cells is eliminated, the epithelial cells cannot surmount, and the occurrence of post-obstacle is prevented.
Further, as shown in fig. 1 to 4, the two annular opening ends of the ring outer body 2 are respectively provided with an inner concave plate body 21 and an outer concave plate body 22, inner ratchet teeth 23 and outer ratchet teeth 24 are respectively and uniformly provided on the inner concave plate body 21 and the outer concave plate body 22, and the inner ratchet teeth 23 are matched with the outer ratchet teeth 24, so that the matching is the tightest.
Further, as shown in fig. 5, the two annular opening ends of the ring outer body 2 are also respectively provided with an inner concave plate body 21 and an outer concave plate body 22, the inner concave plate body 21 and the outer concave plate body 22 are uniformly provided with a groove 25 and a bump 26, the groove 25 is matched with the bump 26, the alignment of the groove 25 and the bump 26 is easier, and thus, the matching of the buckling parts is easier to realize.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (8)
1. A tension ring for preventing post-failure, comprising: including elastic ring inner core (1) and ring outer body (2), ring outer body (2) parcel elastic ring inner core (1), ring outer body (2) material is hydrophobic acrylic ester, elastic ring inner core (1) has the opening with ring outer body (2) elastic ring inner core (1) annular inboard is provided with draws closes tab structure (3), should draw closes tab structure (3) and pass ring outer body (2), is located ring outer body (2) annular inboard, ring outer body (2) opening both ends are provided with the buckling parts of mutually supporting respectively, ring outer body (2) after the lock is closely laminated with lens capsular bag equatorial portion under the elastic tension effect of elastic ring inner core (1).
2. The tension ring for preventing post-amblyopia according to claim 1, wherein: the cross section of the ring outer body (2) is square.
3. The tension ring for preventing post-failure according to claim 1 or 2, wherein: the pull-close loop structure (3) comprises a first pull-close loop (31) and a second pull-close loop (32), and the first pull-close loop (31) and the second pull-close loop (32) are connected to the elastic ring inner core (1).
4. A tension ring for preventing post-failure according to claim 3, wherein: the first pull-close loop (31) is connected to the end part of the elastic ring inner core (1), the second pull-close loop (32) is connected to the annular middle part of the elastic ring inner core (1), and the first pull-close loop (31) and the second pull-close loop (32) are arranged oppositely.
5. The tension ring for preventing post-amblyopia according to claim 4, wherein: the first pull-close loop (31) comprises a connecting graft (33) and a circular ring (34), one end of the connecting branch (33) is connected to the end part of the elastic ring inner core (1), and the other end of the connecting branch (33) is connected with the circular ring (34).
6. The tension ring for preventing post-amblyopia according to claim 5, wherein: the connecting branch (33) is provided with a draw hook part (35), and the connecting branch (33) is connected with the circular ring (34) through the draw hook part (35).
7. The post-prophylaxis tension ring of claim 1, 2, 4, 5 or 6, wherein: the novel ring is characterized in that the two annular opening ends of the ring outer body (2) are respectively provided with an inner concave plate body (21) and an outer concave plate body (22), inner ratchets (23) and outer ratchets (24) are respectively and uniformly arranged on the inner concave plate body (21) and the outer concave plate body (22), and the inner ratchets (23) are matched with the outer ratchets (24).
8. The post-prophylaxis tension ring of claim 1, 2, 4, 5 or 6, wherein: the annular outer body (2) is characterized in that two annular opening ends are respectively provided with an inner concave plate body (21) and an outer concave plate body (22), grooves (25) and protruding blocks (26) are uniformly formed in the inner concave plate body (21) and the outer concave plate body (22), and the grooves (25) are matched with the protruding blocks (26).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311608264.0A CN117357332A (en) | 2023-11-28 | 2023-11-28 | Tension ring for preventing post-failure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311608264.0A CN117357332A (en) | 2023-11-28 | 2023-11-28 | Tension ring for preventing post-failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117357332A true CN117357332A (en) | 2024-01-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311608264.0A Pending CN117357332A (en) | 2023-11-28 | 2023-11-28 | Tension ring for preventing post-failure |
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| Country | Link |
|---|---|
| CN (1) | CN117357332A (en) |
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2023
- 2023-11-28 CN CN202311608264.0A patent/CN117357332A/en active Pending
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