CN117330306A - Imbibition abnormality monitoring method, device and analysis system based on pressure and time - Google Patents
Imbibition abnormality monitoring method, device and analysis system based on pressure and time Download PDFInfo
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- G01—MEASURING; TESTING
- G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
- G01M13/00—Testing of machine parts
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
- G01L11/00—Measuring steady or quasi-steady pressure of a fluid or a fluent solid material by means not provided for in group G01L7/00 or G01L9/00
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Abstract
The application relates to a method, a device and an analysis system for monitoring abnormal liquid absorption based on pressure and time, which belong to the technical field of biochemical analysis systems; monitoring actual pressure data and actual imbibition time of imbibition when the analysis system carries out actual imbibition; and comparing the preset pressure data with the actual pressure data or comparing the preset imbibition time with the actual imbibition time, and judging whether an abnormality exists when the analysis system imbibes. According to the liquid absorption anomaly monitoring method, device and analysis system based on pressure and time, whether the analysis system is abnormal during liquid absorption can be timely and accurately judged by comparing the preset pressure data with the actual pressure data or comparing the preset liquid absorption time with the actual liquid absorption time, the abnormal liquid sample is timely abandoned, and the accuracy of the inspection and analysis results of the liquid sample is improved.
Description
Technical Field
The application relates to the technical field of biochemical analysis systems, in particular to a liquid absorption abnormality monitoring method, device and analysis system based on pressure and time.
Background
Pipetting is an important operation in the field of biological, chemical, and medical detection and analysis, which is the removal of liquid from an original container to another container over a range of ranges. In the prior art, pipetting is usually used with disposable plastic TIP heads (also called TIPs), and the important task of pipetting is to aspirate samples into the TIP heads. Chinese patent publication No. CN116008577a discloses a TIP sampling abnormality detection method and detection device based on pressure detection, which determine the operation state (normal state and abnormal state) of a sampling needle based on pressure detection.
However, the pipetting operation is affected by the quality of the liquid sample, and when the pipetting operation is actually performed, complicated and various abnormal conditions such as blockage, bubble suction, empty suction, even no suction of the sample may occur, any abnormal condition may cause inaccurate detection results of the sample, and some abnormal conditions are difficult to judge through simple pressure detection or weighing and human identification after the pipetting operation is finished, so that a high-precision pipetting abnormality monitoring method is needed to monitor whether the pipetting process is abnormal.
Disclosure of Invention
Based on the above, it is necessary to provide a method, a device and an analysis system for monitoring abnormal pipetting based on pressure and time, so as to solve the technical problem in the prior art that it is difficult to determine whether the pipetting operation is abnormal during pipetting.
To this end, according to one aspect of the present application, there is provided a method for monitoring imbibition abnormality based on pressure and time, applied to an analysis system, the method comprising the steps of:
setting preset pressure data and preset imbibition time of imbibition;
monitoring actual pressure data and actual imbibition time of imbibition when the analysis system carries out actual imbibition;
and comparing the preset pressure data with the actual pressure data or comparing the preset imbibition time with the actual imbibition time, and judging whether the imbibition is abnormal or not.
Optionally, in the process of setting preset pressure data and preset imbibition time of imbibition, performing normal imbibition simulation and drawing a standard time pressure curve, wherein the preset pressure data is obtained based on the standard time pressure curve, and comprises a maximum preset pressure threshold value, a minimum preset pressure threshold value and a preset pressure difference value, and the preset pressure difference value is the difference value between the maximum preset pressure threshold value and the minimum preset pressure threshold value; the actual pressure data includes a maximum actual pressure value, a minimum actual pressure value, and an actual pressure difference value, which is a difference value between the maximum actual pressure value and the minimum actual pressure value.
Optionally, in the process of performing normal liquid absorption simulation, the pressure value before liquid absorption is the maximum preset pressure threshold value, the pressure value in the liquid absorption process is gradually reduced from the maximum preset pressure threshold value to the minimum preset pressure threshold value, and then the pressure value is gradually increased from the minimum preset pressure threshold value to the maximum preset pressure threshold value.
Optionally, if the actual pressure difference is greater than the preset pressure difference, it is determined that a blockage occurs during imbibition.
Optionally, a first judgment pressure value is set between a maximum preset pressure threshold and a minimum preset pressure threshold, and if the pressure value of the actual liquid suction is always between the maximum preset pressure threshold and the first judgment pressure value, the liquid suction is judged not to be carried out.
Optionally, a second judgment pressure value is set between a maximum preset pressure threshold value and a minimum preset pressure threshold value, the preset imbibition time is the time from the first time to the second time of reaching the second judgment pressure value of the standard time pressure curve, the actual imbibition time is the time from the first time to the second judgment pressure value of the actual imbibition, and if the actual imbibition time is smaller than the preset imbibition time, air is inhaled during imbibition judgment.
Optionally, when the actual imbibition is performed, in the process that the pressure value is reduced from the maximum actual pressure value to the minimum actual pressure value, if the pressure value is increased and changed to be larger than the first preset fluctuation difference value, the imbibition of bubbles is judged; or in the process that the pressure value rises from the minimum actual pressure value to the maximum actual pressure value, if the pressure value is larger than the descending change of the second preset fluctuation difference value, the suction of bubbles during the liquid suction is judged.
According to another aspect of the present application, there is provided a liquid suction abnormality monitoring apparatus, for use in an analysis system, the liquid suction abnormality monitoring apparatus including:
the pressure detection module is used for detecting the pressure value in the pump body of the analysis system;
the control processing module is respectively connected with the pressure detection module and the pump body in a communication mode and is used for controlling the start and stop of the pump body according to detection data of the pressure detection module.
According to another aspect of the present application, there is provided an analysis system comprising a memory, a processor and a computer program stored in the memory and executable on the processor, the processor implementing a method of monitoring for imbibition anomalies based on pressure and time as described above when the computer program is executed by the processor.
According to another aspect of the present application, there is provided a computer readable storage medium storing a computer program which when executed by a processor implements a method for monitoring imbibition abnormality based on pressure and time as described above.
Compared with the prior art, the beneficial effects that this application exists are: the method and the device have the advantages that the preset pressure data and the preset imbibition time are set in advance, the actual pressure data and the actual imbibition time of imbibition are monitored when the analysis system performs actual imbibition, the preset pressure data and the actual pressure data are compared, or the preset imbibition time and the actual imbibition time are compared, whether the analysis system imbibition is abnormal or not can be judged more timely and accurately through the comparison of the pressure data and the time data parameters, abnormal liquid samples (such as insufficient liquid amount, clot in a blood sample, foam in a urine sample and the like) can be abandoned in time, and the accuracy of the inspection analysis result of the liquid samples is improved.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic flow chart of a method for monitoring abnormal liquid absorption based on pressure and time according to an embodiment of the present application;
fig. 2 is a schematic structural diagram of a device for monitoring abnormal liquid absorption and liquid absorption provided in an embodiment of the present application;
FIG. 3 is a graph of time versus pressure for an analysis system provided in an embodiment of the present application when operating normally and when there is an anomaly.
Reference numerals illustrate:
10. a pressure detection module; 20. a control processing module; 30. an external embedded master.
Detailed Description
In order to make the above objects, features and advantages of the present application more comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application. This application is, however, susceptible of embodiment in many other forms than those described herein and similar modifications can be made by those skilled in the art without departing from the spirit of the application, and therefore the application is not to be limited to the specific embodiments disclosed below.
In the description of the present application, it should be understood that the terms "center," "longitudinal," "transverse," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," etc. indicate orientations or positional relationships based on the orientation or positional relationships shown in the drawings, are merely for convenience in describing the present application and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be configured and operated in a particular orientation, and therefore should not be construed as limiting the present application.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present application, the meaning of "plurality" is at least two, such as two, three, etc., unless explicitly defined otherwise.
In this application, unless specifically stated and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the terms in this application will be understood by those of ordinary skill in the art as the case may be.
In this application, unless expressly stated or limited otherwise, a first feature "up" or "down" a second feature may be the first and second features in direct contact, or the first and second features in indirect contact via an intervening medium. Moreover, a first feature being "above," "over" and "on" a second feature may be a first feature being directly above or obliquely above the second feature, or simply indicating that the first feature is level higher than the second feature. The first feature being "under", "below" and "beneath" the second feature may be the first feature being directly under or obliquely below the second feature, or simply indicating that the first feature is less level than the second feature.
It will be understood that when an element is referred to as being "fixed" or "disposed" on another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like are used herein for illustrative purposes only and are not meant to be the only embodiment.
As described in the background art, the TIP head is affected by its own mass and sample mass, and may have abnormal conditions such as blocking, air suction, or even non-suction of a sample, and any abnormal condition may result in inaccurate detection results of the sample, and some abnormal conditions are difficult to judge by weighing or human recognition after the liquid suction is finished, so a high-precision liquid suction abnormality monitoring method based on pressure and time is needed to monitor whether an abnormality occurs in the liquid suction process.
In particular, the TIP head may be deformed occasionally due to the influence of the processing level, and the properties of the sample may be different depending on the human body, for example, the aged may have a blood sticky and clotted, and the urine may have foam. These factors can cause anomalies such as blockage of the TIP head, aspiration of bubbles, aspiration of air or even non-aspiration of sample.
In order to solve the above-mentioned problems, referring to fig. 1 to 3 together, an embodiment of the present application provides a method for monitoring imbibition abnormality based on pressure and time, which is applied to an analysis system, and includes the following steps:
step S1: setting preset pressure data and preset imbibition time of imbibition;
step S2: monitoring actual pressure data and actual imbibition time of imbibition when the analysis system carries out actual imbibition;
step S3: and comparing the preset pressure data with the actual pressure data or comparing the preset imbibition time with the actual imbibition time, and judging whether the imbibition is abnormal or not.
In this embodiment of the application, preset pressure data and preset imbibition time are set in advance, still when the analysis system carries out actual imbibition, actual pressure data and actual imbibition time of monitoring imbibition, preset pressure data and actual pressure data or preset imbibition time and actual imbibition time are compared, whether the analysis system imbibition is abnormal or not can be judged more timely and accurately through the comparison of two data parameters of pressure and time, abnormal liquid samples (such as insufficient liquid amount, clot in blood samples, foam in urine samples and the like) can be timely abandoned, and further accuracy of inspection analysis results of the liquid samples is improved.
In one embodiment, referring to fig. 1 and fig. 3 together, in the process of setting the preset pressure data and the preset imbibition time of imbibition, the analysis system performs normal imbibition simulation and draws a standard time pressure curve, the preset pressure data is obtained based on the standard time pressure curve, the preset pressure data comprises a maximum preset pressure threshold value, a minimum preset pressure threshold value and a preset pressure difference value, and the preset pressure difference value is the difference value between the maximum preset pressure threshold value and the minimum preset pressure threshold value; the actual pressure data includes a maximum actual pressure value, a minimum actual pressure value, and an actual pressure difference value, which is a difference value between the maximum actual pressure value and the minimum actual pressure value.
It will be appreciated that the analysis system may be affected by environmental factors when actually pipetting, the actual pipetting environment may not be exactly the same as the simulated pipetting environment, and thus the result may be inaccurate by directly comparing the maximum preset pressure threshold value with the maximum actual pressure value, or by comparing the minimum preset pressure threshold value with the minimum actual pressure value. In the method, whether the abnormality occurs or not is judged by comparing the preset pressure difference value with the actual pressure difference value, compared with the comparison of the maximum value, the difference value is not easily affected by environmental factors, and the abnormality can be judged more accurately.
The derivation of the preset pressure data is explained below:
after the analysis system finishes the first normal liquid absorption simulation, we can inquire the maximum value P in the liquid absorption simulation process through the built-in inquiry function max1 And a minimum value P min1 And can calculate the pressure difference delta P of the liquid suction process 1 The method comprises the steps of carrying out a first treatment on the surface of the The analysis system is completedAfter the second normal liquid absorption simulation, we can inquire the maximum value P in the liquid absorption simulation process through the built-in inquiry function max2 And a minimum value P min2 And can calculate the pressure difference delta P of the liquid suction process 2 The method comprises the steps of carrying out a first treatment on the surface of the Repeating the test for a plurality of times; after the analysis system finishes the n-th normal liquid absorption simulation, the maximum value P in the liquid absorption simulation process can be queried through a built-in query function maxn And a minimum value P minn And can calculate the pressure difference delta P of the liquid suction process n The method comprises the steps of carrying out a first treatment on the surface of the The maximum preset pressure thresholdMinimum preset pressure thresholdPreset pressure difference ∈>。
It can be understood that according to the method for solving the maximum preset pressure threshold and the minimum preset pressure threshold, the average pressure value of each time point when the analysis system performs normal liquid absorption simulation can be obtained, and then the standard time pressure curve can be drawn according to the average pressure value of each time point.
The following explains the derivation of the preset pipetting time:
referring to fig. 3, in the time-pressure graph, two intersections T1 and T2 of the standard time pressure curve and the second judgment pressure value described below can be obtained, and the time difference between T1 and T2 is the preset imbibition time, which is denoted as Δt, Δt=t2-T1.
In other embodiments, considering that the analysis system may be affected by environmental factors when actually absorbing liquid, an error range value x% may be set for the preset pressure difference, and values of x% and y% may be set for the preset liquid absorption time according to the actual environment, which is not limited herein.
In one embodiment, referring to fig. 1 and fig. 3 together, in the process of performing normal liquid absorption simulation by the analysis system, the pressure value before liquid absorption by the analysis system is a maximum preset pressure threshold, the pressure value in the analysis system is gradually reduced from the maximum preset pressure threshold to a minimum preset pressure threshold, and then gradually increased from the minimum preset pressure threshold to the maximum preset pressure threshold.
Specifically, in the process of normal liquid absorption simulation of the analysis system, the analysis system absorbs liquid according to the set liquid absorption parameters and the liquid absorption amount, after liquid absorption starts, the pressure in the analysis system gradually decreases, so that negative pressure is formed between the inside of the analysis system and the outside, the purpose of continuously sucking liquid into the analysis system is achieved, and after the pressure in the analysis system gradually decreases to the minimum preset pressure threshold value, the pressure in the analysis system gradually increases to a level basically equal to the pressure before liquid absorption.
In one embodiment, referring to fig. 1 and fig. 3 together, in step S3, the method further includes the following steps:
step S310: if the actual pressure difference is larger than the preset pressure difference, the system is judged to be blocked when the liquid is actually absorbed by the analysis system.
Specifically, when the analysis system performs actual imbibition, the difference value obtained by subtracting the minimum actual pressure value from the maximum actual pressure value in the imbibition process is recorded as delta Px, if delta Px is greater than delta P, it is proved that the actual pressure difference value of the imbibition exceeds the normal imbibition pressure difference value, and blockage is likely to occur, so that the analysis system is judged to have blockage when the actual imbibition is performed.
Referring to fig. 3, a time-pressure curve of an analysis system in which clogging occurs is shown in fig. 3, because the actual pressure difference of the actual suction exceeds the normal suction pressure difference, and the initial pressure is the same (i.e., the maximum actual pressure value is equal to the maximum preset pressure threshold), the minimum actual pressure of the actual suction is less than the minimum preset pressure threshold.
In one embodiment, referring to fig. 1 and fig. 3 together, in step S3, the method further includes the following steps:
step S320: setting a first judgment pressure value between a maximum preset pressure threshold value and a minimum preset pressure threshold value, and judging that liquid is not sucked when the analysis system sucks liquid if the pressure value in the analysis system is always between the maximum preset pressure threshold value and the first judgment pressure value.
For example, the first judgment pressure value is recorded as a preset pressure difference value obtained by subtracting 20% from a maximum preset pressure threshold value, the difference value obtained by subtracting the minimum actual pressure value from the maximum actual pressure value in the liquid suction process is recorded as Δpx, if Δpx is smaller than Δp×20%, that is, the pressure value in the analysis system always fluctuates within 20% of the preset pressure difference value from the beginning of liquid suction, and the pressure change is too small, so that it is judged that no liquid is sucked when the analysis system sucks liquid.
It is to be understood that the specific value of the first judgment pressure value is set according to actual needs, and is not limited only herein.
In one embodiment, referring to fig. 1 and fig. 3 together, in step S3, the method further includes the following steps:
step S330: setting a second judgment pressure value between a maximum preset pressure threshold value and a minimum preset pressure threshold value, wherein the preset liquid suction time is the time from the first time to the second time of reaching the second judgment pressure value of the standard time pressure curve, the actual liquid suction time is the time from the first time to the second time of reaching the second judgment pressure value of the analysis system in the actual liquid suction process, and if the actual liquid suction time is smaller than the preset liquid suction time, the air is sucked when the analysis system is judged to be actually sucked.
Specifically, referring to fig. 3, the time-pressure curve of the analysis system with sucked air is shown in fig. 3, two intersections of the time-pressure curve with the second judgment pressure value of the sucked air are T3 and T4, respectively, and the actual suction time Δtx=t4-T3, if Δtx is less than Δt, it is proved that a large section of air may be sucked suddenly in the actual suction process, so that the pressure is restored to the pressure level before suction when the pressure has not reached the maximum, and the suction time is too short and is far less than the normal suction time, so that it is judged that the analysis system has suction in the actual suction process and a large amount of air is sucked.
It is to be understood that the specific value of the second judgment pressure value is set according to actual needs, and is not limited only herein.
In one embodiment, referring to fig. 1 and fig. 3 together, in step S3, the method further includes the following steps:
step S340: when the analysis system performs actual imbibition, in the process that the pressure value in the analysis system is reduced from the maximum actual pressure value to the minimum actual pressure value, if the pressure value in the analysis system is increased and changed to be larger than a first preset fluctuation difference value, the suction bubbles are judged when the analysis system performs actual imbibition; or in the process that the pressure value in the analysis system is increased from the minimum actual pressure value to the maximum actual pressure value, if the pressure value in the analysis system is decreased and changed to be larger than the second preset fluctuation difference value, the suction of bubbles is judged when the analysis system actually sucks liquid.
For example, referring to fig. 3, a time-pressure curve of an analysis system having a suction bubble is shown in fig. 3, for example, in a process that a pressure value in the analysis system is reduced from a maximum actual pressure value to a minimum actual pressure value, a rising change Δ1 occurs in the pressure value in the analysis system, where Δ1 is greater than a first preset fluctuation difference value, so that it is determined that the analysis system sucks the bubble when it actually sucks the suction bubble.
Or judging whether continuous pressure data become larger and then smaller fluctuation exists in the liquid suction process, assuming that the time of one group of pressure data is Pn at the front and P (n-1) at the back, if the continuous multiple groups of pressure data Pn-P (n-1) > 0 and then Pn-P (n-1) < 0 immediately appear, judging that the pressure fluctuation exists in the liquid suction process, the pressure of the bubbles is reduced immediately after the bubbles are completely sucked, and starting to suck the water pressure and then starting to rise suddenly again, and judging that the analysis system sucks the bubbles in the actual liquid suction process.
In other embodiments, after the liquid absorption is determined to be abnormal, whether the liquid sample is abnormal or the analysis system is abnormal may be deduced approximately reversely according to the type of the abnormality; for example, when an analysis system is blocked, the analysis system usually has a problem of quality of the TIP itself or a viscous clot in a liquid sample, the analysis system usually has no liquid sucked in, which is caused by a pump failure of the analysis system or a problem of quality of the TIP itself, the analysis system sucks a large amount of air, which is caused by a problem of quality of the TIP itself, and the analysis system sucks bubbles, which is caused by a foam in the liquid sample.
Therefore, the problem source of abnormality is probably reversely deduced according to the abnormality type, so that the liquid sample is replaced or the analysis system is maintained in time, and the liquid absorption efficiency and the liquid sample analysis efficiency are improved.
According to another aspect of the present application, there is provided a device for monitoring abnormal liquid absorption, for use in an analysis system, referring to fig. 2, the device comprising:
a pressure detection module 10 for detecting a pressure value in a pump body of the analysis system;
the control processing module 20 is respectively connected to the pressure detection module 10 and the pump body in a communication manner, and the control processing module 20 is used for controlling the start and stop of the pump body according to the detection data of the pressure detection module 10.
In one embodiment, the device for monitoring abnormal liquid absorption further includes an external embedded main control 30, where the external embedded main control 30 is communicatively connected to the control processing module 20, and the external embedded main control 30 is capable of receiving external control instructions and transmitting the control instructions related to the control processing module 20.
Specifically, the pump body mainly comprises a pump cavity, a connecting rod and a pump driving assembly, wherein the pump cavity is mainly used for storing gas entering from a TIP end and replacing the gas with liquid, and the pump driving assembly is mainly used for driving a piston in the pump cavity to move; the pressure detection module 10 comprises a pressure sensor and a circuit, and is mainly used for detecting the pressure of the pump cavity in the imbibition process; the control processing module 20 is mainly used for controlling the motor operation of the pump driving assembly, the signal processing of the pressure sensor and the signal alarming.
It will be apparent to those skilled in the art that, for convenience and brevity of description, only the above-described division of the functional units and modules is illustrated, and in practical application, the above-described functional distribution may be performed by different functional units and modules according to needs, i.e. the internal structure of the apparatus is divided into different functional units or modules to perform all or part of the above-described functions. The functional units and modules in the embodiment may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit, where the integrated units may be implemented in a form of hardware or a form of a software functional unit. In addition, specific names of the functional units and modules are only for convenience of distinguishing from each other, and are not used for limiting the protection scope of the present application. The specific working process of the units and modules in the above system may refer to the corresponding process in the foregoing method embodiment, which is not described herein again.
According to another aspect of the present application, there is provided an analysis system comprising a memory, a processor and a computer program stored in the memory and executable on the processor, the processor implementing a method of monitoring for imbibition anomalies based on pressure and time as described above when the computer program is executed by the processor.
According to another aspect of the present application, there is provided a computer readable storage medium storing a computer program which when executed by a processor implements a method for monitoring imbibition abnormality based on pressure and time as described above.
In the above embodiments of the present application, preset pressure data and preset imbibition time are set in advance, and when the analysis system performs actual imbibition, the actual pressure data and the actual imbibition time of imbibition are monitored, the preset pressure data and the actual pressure data are compared, or the preset imbibition time and the actual imbibition time are compared, and by comparing the pressure and the time two data parameters, whether an abnormality exists when the analysis system imbibites can be more timely and accurately judged, so that an abnormal liquid sample (such as insufficient liquid amount, clot in a blood sample, foam in a urine sample, etc.) can be timely abandoned, and further the accuracy of the inspection analysis result of the liquid sample is improved.
Specifically, when the pump body of the analysis system of the application sucks the liquid sample, whether the liquid sample is blocked due to the defect of a sample clot or TIP (TIP) can be judged through pressure change and time change; or sucking a section of liquid in the liquid sucking process, and homogenizing air in the second half section; or the liquid suction is inaccurate due to the existence of bubbles in the liquid suction process; or the analysis system does not suck liquid and the like, so that the possibility of error results in the final test can be reduced, the liquid suction can be known to be wrong in advance, the liquid suction can be timely restarted, the time is saved, and the efficiency is improved.
In the foregoing embodiments, the descriptions of the embodiments are emphasized, and in part, not described or illustrated in any particular embodiment, reference is made to the related descriptions of other embodiments.
Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware, or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the solution. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.
In the embodiments provided in the present application, it should be understood that the disclosed apparatus/terminal and method may be implemented in other manners. For example, the apparatus/terminal embodiments described above are merely illustrative, e.g., the division of the modules or units described above is merely a logical functional division, and there may be additional divisions when actually implemented, e.g., multiple units or components may be combined or integrated into another system, or some features may be omitted or not performed. Alternatively, the coupling or direct coupling or communication connection shown or discussed may be an indirect coupling or communication connection via interfaces, devices or units, which may be in electrical, mechanical or other forms.
The units described above as separate components may or may not be physically separate, and components shown as units may or may not be physical units, may be located in one place, or may be distributed over a plurality of network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.
In addition, each functional unit in each embodiment of the present application may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit. The integrated units may be implemented in hardware or in software functional units.
The integrated modules/units described above, if implemented in the form of software functional units and sold or used as stand-alone products, may be stored in a computer readable storage medium. Based on such understanding, the present application may implement all or part of the flow of the method of the above embodiment, or may be implemented by a computer program to instruct related hardware, where the above computer program may be stored in a computer readable storage medium, and when the computer program is executed by a processor, the computer program may implement the steps of each method embodiment described above. The computer program comprises computer program code, and the computer program code can be in a source code form, an object code form, an executable file or some intermediate form and the like. The computer readable medium may include: any entity or device capable of carrying the computer program code described above, a recording medium, a U disk, a removable hard disk, a magnetic disk, an optical disk, a computer Memory, a Read-Only Memory (ROM), a random access Memory (RandomAccess Memory, RAM), an electrical carrier wave signal, a telecommunications signal, a software distribution medium, and so forth. It should be noted that the content of the computer readable medium described above can be appropriately increased or decreased according to the requirements of the jurisdiction's legislation and the patent practice, for example, in some jurisdictions, the computer readable medium does not include electrical carrier signals and telecommunication signals according to the legislation and the patent practice.
The above embodiments are only for illustrating the technical solution of the present application, and are not limiting thereof; although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present application, and are intended to be included in the scope of the present application.
Claims (10)
1. The method for monitoring the abnormal liquid absorption based on the pressure and the time is characterized by being applied to an analysis system, and comprises the following steps of:
setting preset pressure data and preset imbibition time of imbibition;
monitoring actual pressure data and actual imbibition time of imbibition when the analysis system carries out actual imbibition;
and comparing the preset pressure data with the actual pressure data or comparing the preset liquid suction time with the actual liquid suction time, and judging whether the liquid suction is abnormal or not.
2. The method for monitoring abnormal liquid suction based on pressure and time according to claim 1, wherein in the process of setting preset pressure data and preset liquid suction time of liquid suction, normal liquid suction simulation is performed and a standard time pressure curve is drawn, wherein the preset pressure data is obtained based on the standard time pressure curve, the preset pressure data comprises a maximum preset pressure threshold value, a minimum preset pressure threshold value and a preset pressure difference value, and the preset pressure difference value is the difference value between the maximum preset pressure threshold value and the minimum preset pressure threshold value; the actual pressure data includes a maximum actual pressure value, a minimum actual pressure value, and an actual pressure difference value, which is a difference value between the maximum actual pressure value and the minimum actual pressure value.
3. The method for monitoring abnormal liquid suction based on pressure and time according to claim 2, wherein in the process of performing normal liquid suction simulation, the pressure value before liquid suction is the maximum preset pressure threshold value, the pressure value in the liquid suction process is gradually reduced from the maximum preset pressure threshold value to the minimum preset pressure threshold value, and then gradually increased from the minimum preset pressure threshold value to the maximum preset pressure threshold value.
4. The method for monitoring abnormal liquid suction based on pressure and time according to claim 3, wherein if the actual pressure difference is greater than the preset pressure difference, it is determined that clogging occurs during actual liquid suction.
5. A method of monitoring abnormal liquid suction based on pressure and time according to claim 3, wherein a first judgment pressure value is set between the maximum preset pressure threshold and the minimum preset pressure threshold, and if the pressure value of the actual liquid suction is always between the maximum preset pressure threshold and the first judgment pressure value, it is judged that the liquid is not sucked during the actual liquid suction.
6. A method of monitoring abnormal liquid suction based on pressure and time according to claim 3, wherein a second judgment pressure value is set between the maximum preset pressure threshold and the minimum preset pressure threshold, the preset liquid suction time is the time from the first time to the second time when the standard time pressure curve reaches the second judgment pressure value, the actual liquid suction time is the time from the first time to the second time when the actual liquid suction reaches the second judgment pressure value, and if the actual liquid suction time is smaller than the preset liquid suction time, air suction is judged when the actual liquid suction is performed.
7. The abnormal monitoring method for imbibition based on pressure and time according to claim 3, wherein when actual imbibition is performed, if the pressure value is increased and changed to be larger than a first preset fluctuation difference value in the process that the pressure value is reduced from the maximum actual pressure value to the minimum actual pressure value, the imbibition bubble is judged when the actual imbibition is performed; or in the process that the pressure value rises from the minimum actual pressure value to the maximum actual pressure value, if the pressure value is larger than the descending change of the second preset fluctuation difference value, the air bubble is sucked in during actual liquid suction.
8. A liquid suction abnormality monitoring device, characterized by being applied to an analysis system, comprising:
the pressure detection module is used for detecting a pressure value in a pump body of the analysis system;
the control processing module is respectively connected with the pressure detection module and the pump body in a communication mode, and the control processing module is used for controlling the start and stop of the pump body according to the detection data of the pressure detection module.
9. An analysis system comprising a memory, a processor and a computer program stored in the memory and executable on the processor, wherein the processor, when executing the computer program, implements a pressure and time based fluid absorption anomaly monitoring method as claimed in any one of claims 1 to 7.
10. A computer readable storage medium storing a computer program, wherein the computer program when executed by a processor implements the pressure and time based fluid intake anomaly monitoring method of any one of claims 1-7.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311591576.5A CN117330306A (en) | 2023-11-27 | 2023-11-27 | Imbibition abnormality monitoring method, device and analysis system based on pressure and time |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202311591576.5A CN117330306A (en) | 2023-11-27 | 2023-11-27 | Imbibition abnormality monitoring method, device and analysis system based on pressure and time |
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| CN202311591576.5A Pending CN117330306A (en) | 2023-11-27 | 2023-11-27 | Imbibition abnormality monitoring method, device and analysis system based on pressure and time |
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| CN (1) | CN117330306A (en) |
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